1     M         1.915   1.918   1.995   2.209   2.214   2.334   2.133   2.137   2.257
2     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    N        -0.526  -0.503  -0.480  -0.431  -0.399  -0.353  -0.629  -0.605  -0.558
19    Y        -1.375  -1.369  -1.288  -1.194  -1.192  -1.064  -1.055  -1.049  -0.946
20    N        -0.102  -0.100  -0.017  -0.188  -0.184  -0.059  -0.417  -0.413  -0.305
21    L         0.071   0.070   0.087   0.034   0.034   0.075  -0.209  -0.209  -0.174
22    S         0.160   0.160   0.104   0.104   0.104   0.012  -0.053  -0.053  -0.136
23    K         0.817   0.796   0.791   0.556   0.512   0.441   0.572   0.530   0.471
24    Y         0.643   0.645   0.725   0.470   0.474   0.597   0.221   0.224   0.336
25    P         1.915   1.918   1.995   1.934   1.937   2.060   2.133   2.137   2.257
26    D        -1.294  -1.284  -1.240  -1.195  -1.181  -1.114  -0.989  -0.980  -0.909
27    D        -1.294  -1.306  -1.260  -1.003  -1.016  -0.964  -0.989  -0.998  -0.925
28    V        -0.430  -0.439  -0.444  -0.326  -0.335  -0.345  -0.521  -0.529  -0.518
29    S        -0.430  -0.439  -0.444  -0.376  -0.381  -0.382  -0.521  -0.529  -0.518
30    R        -0.430  -0.444  -0.445  -0.686  -0.711  -0.722  -0.521  -0.537  -0.520
31    L         1.915   1.918   1.995   1.982   1.988   2.108   2.133   2.137   2.257
32    F         1.915   1.918   1.995   2.123   2.128   2.249   2.133   2.137   2.257
33    K        -0.930  -0.939  -0.901  -0.870  -0.882  -0.816  -0.833  -0.839  -0.772
34    P        -0.793  -0.803  -0.832  -0.652  -0.668  -0.710  -0.677  -0.687  -0.700
35    R        -0.430  -0.438  -0.442  -0.682  -0.688  -0.659  -0.521  -0.527  -0.514
36    P         1.915   1.918   1.995   1.925   1.929   2.051   2.133   2.137   2.257
37    P         0.453   0.414   0.254   0.535   0.480   0.225   0.416   0.358   0.104
38    L         0.453   0.435   0.261   0.628   0.602   0.347   0.416   0.388   0.115
39    S        -0.430  -0.406  -0.427  -0.672  -0.648  -0.660  -0.521  -0.498  -0.497
40    Y         1.088   1.069   0.963   1.287   1.264   1.110   1.071   1.038   0.813
41    K        -0.430  -0.434  -0.438  -0.493  -0.498  -0.495  -0.521  -0.527  -0.510
42    R        -0.930  -0.930  -0.893  -1.174  -1.176  -1.092  -0.833  -0.832  -0.765
43    P         0.453   0.437   0.252   0.501   0.477   0.166   0.416   0.392   0.101
44    T        -1.294  -1.284  -1.240  -0.922  -0.901  -0.838  -0.989  -0.980  -0.909
45    D         0.453   0.437   0.252   0.601   0.576   0.263   0.416   0.392   0.101
46    Y         0.160   0.146   0.119   0.152   0.128   0.053  -0.053  -0.072  -0.117
47    P        -0.203  -0.238  -0.354  -0.143  -0.196  -0.402  -0.209  -0.253  -0.397
48    Y        -0.430  -0.416  -0.442  -0.503  -0.484  -0.530  -0.521  -0.505  -0.517
49    A        -0.203  -0.204  -0.363  -0.076  -0.081  -0.345  -0.209  -0.209  -0.409
50    K        -0.430  -0.421  -0.435  -0.486  -0.473  -0.489  -0.521  -0.515  -0.510
51    R         0.453   0.437   0.252   0.336   0.313   0.073   0.416   0.392   0.101
52    Q        -0.930  -0.911  -0.889  -1.079  -1.067  -0.993  -0.833  -0.816  -0.763
53    T         0.453   0.437   0.252   0.690   0.670   0.381   0.416   0.392   0.101
54    N        -1.294  -1.311  -1.245  -1.072  -1.098  -1.012  -0.989  -1.002  -0.913
55    P        -0.793  -0.794  -0.830  -0.735  -0.744  -0.807  -0.677  -0.678  -0.697
56    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
57    I         0.160   0.151   0.122   0.218   0.204   0.153  -0.053  -0.067  -0.111
58    T         0.661   0.671   0.735   0.440   0.460   0.554   0.260   0.278   0.356
59    G        -0.203  -0.189  -0.335  -0.124  -0.102  -0.341  -0.209  -0.190  -0.373
60    V         0.453   0.455   0.282   0.721   0.725   0.494   0.416   0.419   0.148
61    A         0.817   0.825   0.818   0.706   0.725   0.694   0.572   0.588   0.526
62    N        -0.930  -0.931  -0.896  -0.896  -0.890  -0.833  -0.833  -0.832  -0.769
63    L        -1.294  -1.280  -1.256  -1.012  -0.991  -0.956  -0.989  -0.976  -0.922
64    L        -0.793  -0.798  -0.834  -0.675  -0.670  -0.757  -0.677  -0.682  -0.702
65    S        -1.294  -1.306  -1.260  -1.109  -1.126  -1.084  -0.989  -0.998  -0.925
66    T        -1.294  -1.292  -1.253  -0.987  -0.983  -0.925  -0.989  -0.987  -0.919
67    S        -1.294  -1.284  -1.242  -0.983  -0.969  -0.904  -0.989  -0.980  -0.910
68    L        -1.294  -1.303  -1.250  -1.124  -1.135  -1.066  -0.989  -0.996  -0.917
69    K        -0.526  -0.522  -0.483  -0.645  -0.635  -0.582  -0.629  -0.625  -0.561
70    H         0.058   0.037   0.062   0.117   0.086   0.122  -0.204  -0.230  -0.198
71    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
72    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
73    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
74    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
75    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
76    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
77    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
78    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
79    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
80    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
81    Y        -0.066  -0.072   0.000  -0.233  -0.240  -0.130  -0.365  -0.373  -0.280
82    M        -1.658  -1.656  -1.570  -1.339  -1.342  -1.209  -1.146  -1.143  -1.038
83    E        -0.430  -0.443  -0.451  -0.316  -0.334  -0.331  -0.521  -0.536  -0.528
84    E        -1.294  -1.280  -1.256  -1.058  -1.032  -1.007  -0.989  -0.976  -0.922
85    F        -0.567  -0.554  -0.506  -0.432  -0.415  -0.341  -0.677  -0.665  -0.589
86    P         1.915   1.918   1.995   1.925   1.929   2.051   2.133   2.137   2.257
87    -        -0.531  -0.530  -0.504  -0.617  -0.632  -0.614  -0.621  -0.620  -0.580
88    E         1.088   1.094   0.971   1.169   1.177   0.981   1.071   1.080   0.828
89    G        -0.930  -0.921  -0.894  -0.869  -0.855  -0.802  -0.833  -0.824  -0.767
90    S        -0.793  -0.804  -0.828  -0.592  -0.598  -0.624  -0.677  -0.688  -0.696
91    P        -1.294  -1.290  -1.244  -1.178  -1.170  -1.107  -0.989  -0.985  -0.912
92    N        -1.294  -1.299  -1.252  -1.000  -1.005  -0.947  -0.989  -0.992  -0.918
93    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
94    N        -0.793  -0.775  -0.842  -0.750  -0.726  -0.838  -0.677  -0.657  -0.710
95    H         0.160   0.159   0.122   0.272   0.270   0.172  -0.053  -0.053  -0.112
96    L        -0.203  -0.196  -0.341  -0.032  -0.019  -0.250  -0.209  -0.199  -0.382
97    Q        -0.430  -0.436  -0.446  -0.706  -0.717  -0.709  -0.521  -0.525  -0.522
98    R        -0.930  -0.930  -0.896  -1.134  -1.137  -1.063  -0.833  -0.832  -0.768
99    Y        -0.930  -0.936  -0.895  -0.909  -0.914  -0.856  -0.833  -0.837  -0.768
100   E        -0.793  -0.777  -0.830  -0.663  -0.644  -0.748  -0.677  -0.659  -0.698
101   D        -0.793  -0.791  -0.826  -0.719  -0.711  -0.794  -0.677  -0.674  -0.693
102   I         0.006   0.036   0.050  -0.028   0.023   0.032  -0.258  -0.212  -0.206
103   K        -0.630  -0.625  -0.545  -0.590  -0.577  -0.461  -0.736  -0.730  -0.626
104   L         0.006   0.016   0.045  -0.085  -0.068  -0.037  -0.258  -0.243  -0.213
105   S        -0.203  -0.204  -0.363  -0.224  -0.226  -0.526  -0.209  -0.209  -0.409
106   K        -0.930  -0.935  -0.888  -1.085  -1.087  -1.023  -0.833  -0.836  -0.761
107   I        -1.658  -1.656  -1.570  -1.520  -1.526  -1.389  -1.146  -1.143  -1.038
108   K        -1.294  -1.299  -1.252  -1.294  -1.308  -1.234  -0.989  -0.992  -0.918
109   N        -0.930  -0.917  -0.904  -0.801  -0.777  -0.769  -0.833  -0.820  -0.776
110   A        -0.793  -0.798  -0.828  -0.708  -0.719  -0.800  -0.677  -0.681  -0.695
111   Q        -0.930  -0.940  -0.900  -1.032  -1.049  -0.988  -0.833  -0.840  -0.772
112   L        -1.294  -1.285  -1.250  -1.283  -1.265  -1.231  -0.989  -0.980  -0.917
113   L        -0.793  -0.798  -0.834  -0.537  -0.545  -0.589  -0.677  -0.682  -0.702
114   D        -0.930  -0.925  -0.886  -0.880  -0.876  -0.813  -0.833  -0.828  -0.760
115   R        -1.294  -1.301  -1.243  -1.488  -1.496  -1.397  -0.989  -0.994  -0.911
116   R        -0.430  -0.435  -0.437  -0.526  -0.538  -0.544  -0.521  -0.526  -0.512
117   L         0.160   0.139   0.115   0.152   0.122   0.073  -0.053  -0.081  -0.123
118   Q        -0.930  -0.926  -0.893  -0.849  -0.846  -0.788  -0.833  -0.829  -0.766
119   N        -0.793  -0.811  -0.846  -0.567  -0.594  -0.638  -0.677  -0.696  -0.714
120   W         1.915   1.918   1.995   2.260   2.265   2.386   2.133   2.137   2.257
121   N         0.071   0.072   0.080   0.134   0.136   0.174  -0.209  -0.206  -0.182
122   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
123   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
124   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
125   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
126   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
127   P         0.453   0.486   0.268   0.579   0.624   0.316   0.416   0.465   0.126
128   N        -0.793  -0.796  -0.841  -0.673  -0.676  -0.740  -0.677  -0.680  -0.709
129   V        -1.294  -1.285  -1.250  -1.090  -1.078  -1.009  -0.989  -0.980  -0.917
130   D         0.817   0.837   0.830   0.793   0.827   0.792   0.572   0.610   0.551
131   P        -1.294  -1.293  -1.247  -1.318  -1.314  -1.218  -0.989  -0.987  -0.915
132   H        -0.430  -0.438  -0.442  -0.253  -0.260  -0.272  -0.521  -0.527  -0.514
133   I        -0.430  -0.434  -0.430  -0.215  -0.214  -0.195  -0.521  -0.522  -0.500
134   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
135   D        -0.930  -0.942  -0.907  -0.698  -0.715  -0.669  -0.833  -0.842  -0.778
136   T        -0.567  -0.566  -0.515  -0.713  -0.709  -0.631  -0.677  -0.675  -0.597
137   D         1.915   1.918   1.995   2.025   2.028   2.151   2.133   2.137   2.257
138   P         1.915   1.918   1.995   1.925   1.929   2.051   2.133   2.137   2.257
139   Y         0.661   0.664   0.734   0.604   0.610   0.715   0.260   0.264   0.354
140   R         0.661   0.666   0.732   0.190   0.202   0.282   0.260   0.269   0.350
141   T         1.915   1.918   1.995   2.062   2.068   2.188   2.133   2.137   2.257
142   I        -0.430  -0.427  -0.437  -0.305  -0.304  -0.299  -0.521  -0.520  -0.512
143   F         1.915   1.918   1.995   2.123   2.128   2.249   2.133   2.137   2.257
144   I         0.071   0.071   0.086   0.051   0.053   0.086  -0.209  -0.208  -0.174
145   G        -0.066  -0.064  -0.006  -0.280  -0.273  -0.189  -0.365  -0.362  -0.289
146   R         1.915   1.918   1.995   1.661   1.662   1.788   2.133   2.137   2.257
147   L         1.915   1.918   1.995   1.982   1.988   2.108   2.133   2.137   2.257
148   P        -0.930  -0.942  -0.907  -0.832  -0.847  -0.781  -0.833  -0.842  -0.778
149   Y         1.162   1.137   1.014   1.384   1.354   1.188   1.197   1.154   0.908
150   D        -0.203  -0.176  -0.340   0.049   0.089  -0.154  -0.209  -0.174  -0.380
151   L        -0.066  -0.076  -0.009  -0.163  -0.178  -0.077  -0.365  -0.379  -0.292
152   D         0.071   0.070   0.076   0.027   0.026   0.041  -0.209  -0.209  -0.186
153   E         1.915   1.918   1.995   1.971   1.975   2.097   2.133   2.137   2.257
154   I        -0.930  -0.934  -0.904  -0.813  -0.812  -0.763  -0.833  -0.836  -0.776
155   E         0.160   0.154   0.104   0.178   0.171   0.084  -0.053  -0.058  -0.137
156   L         0.661   0.668   0.744   0.509   0.524   0.636   0.260   0.273   0.374
157   Q        -0.066  -0.064   0.002  -0.244  -0.237  -0.148  -0.365  -0.361  -0.276
158   K         0.160   0.141   0.118  -0.092  -0.121  -0.187  -0.053  -0.077  -0.117
159   Y        -1.658  -1.656  -1.570  -1.285  -1.279  -1.155  -1.146  -1.143  -1.038
160   F         1.162   1.137   1.014   1.441   1.409   1.235   1.197   1.154   0.908
161   V        -0.930  -0.930  -0.891  -0.780  -0.773  -0.717  -0.833  -0.832  -0.764
162   K         0.817   0.819   0.817   0.556   0.561   0.503   0.572   0.575   0.524
163   F         0.817   0.813   0.796   0.878   0.873   0.826   0.572   0.564   0.482
164   G         1.915   1.918   1.995   1.922   1.924   2.048   2.133   2.137   2.257
165   E        -0.930  -0.917  -0.904  -0.828  -0.814  -0.762  -0.833  -0.820  -0.776
166   I         1.162   1.137   1.014   1.377   1.348   1.170   1.197   1.154   0.908
167   E         0.453   0.414   0.254   0.594   0.538   0.289   0.416   0.358   0.104
168   K        -0.430  -0.439  -0.445  -0.648  -0.662  -0.671  -0.521  -0.533  -0.521
169   I         0.160   0.143   0.105   0.294   0.266   0.223  -0.053  -0.081  -0.138
170   R         1.162   1.194   1.023   0.982   1.020   0.802   1.197   1.249   0.926
171   I         0.817   0.807   0.805   0.851   0.837   0.805   0.572   0.553   0.500
172   V         1.162   1.169   1.018   1.353   1.363   1.157   1.197   1.208   0.916
173   K         1.162   1.182   1.019   0.953   0.977   0.747   1.197   1.228   0.918
174   D         1.162   1.160   1.029   1.354   1.352   1.182   1.197   1.193   0.936
175   K         0.453   0.428   0.256   0.539   0.507   0.249   0.416   0.379   0.107
176   I         0.006   0.025   0.044  -0.072  -0.043  -0.015  -0.258  -0.229  -0.215
177   T        -0.930  -0.929  -0.888  -0.821  -0.819  -0.759  -0.833  -0.831  -0.762
178   Q         0.453   0.454   0.253   0.588   0.589   0.310   0.416   0.417   0.103
179   K         1.915   1.918   1.995   1.900   1.907   2.026   2.133   2.137   2.257
180   S         1.915   1.918   1.995   1.898   1.906   2.023   2.133   2.137   2.257
181   K        -0.203  -0.213  -0.333  -0.283  -0.294  -0.441  -0.209  -0.221  -0.371
182   G         1.915   1.918   1.995   1.922   1.924   2.048   2.133   2.137   2.257
183   Y         1.915   1.918   1.995   2.054   2.060   2.180   2.133   2.137   2.257
184   A         0.661   0.662   0.735   0.458   0.459   0.571   0.260   0.260   0.356
185   F         1.915   1.918   1.995   2.123   2.128   2.249   2.133   2.137   2.257
186   I         1.162   1.182   1.019   1.353   1.379   1.159   1.197   1.228   0.918
187   V        -0.203  -0.238  -0.354   0.015  -0.039  -0.229  -0.209  -0.253  -0.397
188   F         1.162   1.169   1.018   1.441   1.452   1.242   1.197   1.208   0.916
189   K        -0.430  -0.446  -0.456  -0.451  -0.474  -0.479  -0.521  -0.539  -0.531
190   D        -0.430  -0.429  -0.451  -0.725  -0.727  -0.730  -0.521  -0.523  -0.528
191   P        -1.294  -1.280  -1.256  -1.068  -1.046  -1.004  -0.989  -0.976  -0.922
192   I        -0.930  -0.922  -0.889  -0.921  -0.910  -0.862  -0.833  -0.824  -0.763
193   S         0.817   0.818   0.810   0.765   0.768   0.716   0.572   0.574   0.510
194   S        -0.430  -0.444  -0.440  -0.374  -0.387  -0.381  -0.521  -0.535  -0.513
195   K         0.160   0.149   0.112  -0.033  -0.065  -0.122  -0.053  -0.075  -0.128
196   M        -1.294  -1.284  -1.242  -1.023  -1.011  -0.945  -0.989  -0.980  -0.910
197   A         0.661   0.661   0.735   0.741   0.739   0.846   0.260   0.257   0.356
198   F        -0.793  -0.784  -0.822  -0.442  -0.427  -0.492  -0.677  -0.667  -0.689
199   K        -0.430  -0.446  -0.441  -0.629  -0.658  -0.631  -0.521  -0.540  -0.514
200   E         0.679   0.672   0.736   0.540   0.525   0.618   0.297   0.281   0.358
201   I         0.679   0.678   0.743   0.519   0.518   0.610   0.297   0.293   0.372
202   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
203   V        -0.430  -0.436  -0.449  -0.307  -0.310  -0.324  -0.521  -0.525  -0.524
204   H        -0.930  -0.930  -0.893  -0.982  -0.979  -0.935  -0.833  -0.832  -0.765
205   R        -0.930  -0.942  -0.907  -1.005  -1.021  -0.951  -0.833  -0.842  -0.778
206   G         1.915   1.918   1.995   1.922   1.924   2.048   2.133   2.137   2.257
207   I         0.071   0.056   0.071  -0.005  -0.020   0.002  -0.209  -0.225  -0.193
208   Q        -0.930  -0.942  -0.907  -0.815  -0.824  -0.753  -0.833  -0.842  -0.778
209   I         0.817   0.819   0.817   0.832   0.840   0.804   0.572   0.575   0.524
210   K        -0.930  -0.917  -0.886  -0.816  -0.790  -0.743  -0.833  -0.820  -0.760
211   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
212   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
213   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
214   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
215   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
216   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
217   D        -0.203  -0.161  -0.330  -0.037   0.021  -0.214  -0.209  -0.154  -0.368
218   R         1.915   1.918   1.995   1.661   1.662   1.788   2.133   2.137   2.257
219   I        -0.930  -0.931  -0.891  -1.075  -1.086  -1.013  -0.833  -0.833  -0.764
220   C        -0.430  -0.446  -0.456  -0.217  -0.236  -0.255  -0.521  -0.539  -0.531
221   I        -0.066  -0.064   0.002  -0.143  -0.136  -0.044  -0.365  -0.361  -0.276
222   V         1.915   1.918   1.995   2.033   2.036   2.159   2.133   2.137   2.257
223   D         1.915   1.918   1.995   2.025   2.028   2.151   2.133   2.137   2.257
224   I         0.160   0.173   0.129   0.280   0.291   0.249  -0.053  -0.042  -0.098
225   E         1.915   1.918   1.995   1.971   1.975   2.097   2.133   2.137   2.257
226   R         1.915   1.918   1.995   1.661   1.662   1.788   2.133   2.137   2.257
227   G         1.162   1.169   1.018   1.215   1.224   1.002   1.197   1.208   0.916
228   R         1.915   1.918   1.995   1.661   1.662   1.788   2.133   2.137   2.257
229   T         0.453   0.486   0.268   0.700   0.748   0.423   0.416   0.465   0.126
230   V         0.453   0.443   0.264   0.677   0.663   0.398   0.416   0.401   0.120
231   K         0.453   0.457   0.272   0.449   0.460   0.135   0.416   0.421   0.132
232   Y        -0.567  -0.558  -0.514  -0.499  -0.490  -0.408  -0.677  -0.669  -0.596
233   F         0.661   0.662   0.732   0.769   0.772   0.868   0.260   0.261   0.349
234   K         0.160   0.154   0.122  -0.015  -0.027  -0.103  -0.053  -0.066  -0.108
235   P         1.915   1.918   1.995   1.925   1.929   2.051   2.133   2.137   2.257
236   R         1.915   1.918   1.995   1.661   1.662   1.788   2.133   2.137   2.257
237   R         1.162   1.160   1.029   0.953   0.948   0.762   1.197   1.193   0.936
238   L         1.915   1.918   1.995   1.982   1.988   2.108   2.133   2.137   2.257
239   G         1.915   1.918   1.995   1.922   1.924   2.048   2.133   2.137   2.257
240   G         1.915   1.918   1.995   1.922   1.924   2.048   2.133   2.137   2.257
241   G         1.915   1.918   1.995   1.922   1.924   2.048   2.133   2.137   2.257
242   L         0.453   0.435   0.261   0.592   0.567   0.292   0.416   0.388   0.115
243   G         1.915   1.918   1.995   1.922   1.924   2.048   2.133   2.137   2.257
244   G         1.915   1.918   1.995   1.922   1.924   2.048   2.133   2.137   2.257
245   R         1.915   1.918   1.995   1.661   1.662   1.788   2.133   2.137   2.257
246   G         0.661   0.663   0.739   0.539   0.540   0.660   0.260   0.261   0.363
247   Y         1.915   1.918   1.995   2.054   2.060   2.180   2.133   2.137   2.257
248   S        -0.430  -0.419  -0.448  -0.349  -0.333  -0.382  -0.521  -0.511  -0.523
249   N        -0.430  -0.422  -0.444  -0.668  -0.649  -0.690  -0.521  -0.510  -0.519
250   R        -0.793  -0.775  -0.842  -0.802  -0.768  -0.929  -0.677  -0.657  -0.710
251   D        -0.526  -0.527  -0.488  -0.571  -0.573  -0.503  -0.629  -0.629  -0.567
252   S        -0.950  -0.958  -0.914  -1.036  -1.042  -0.987  -0.842  -0.850  -0.782
253   R        -0.526  -0.516  -0.477  -0.715  -0.715  -0.632  -0.629  -0.619  -0.556
254   L         0.006  -0.007   0.043  -0.017  -0.041   0.036  -0.258  -0.278  -0.217
255   P         0.006   0.005   0.050  -0.168  -0.169  -0.107  -0.258  -0.259  -0.206
256   G        -0.531  -0.531  -0.494  -0.476  -0.475  -0.439  -0.621  -0.621  -0.568
257   R        -1.040  -1.036  -0.954  -1.239  -1.220  -1.109  -0.927  -0.923  -0.818
258   F        -1.375  -1.369  -1.288  -1.123  -1.123  -0.994  -1.055  -1.049  -0.946
259   A        -0.950  -0.959  -0.922  -0.932  -0.944  -0.881  -0.842  -0.850  -0.789
260   S        -1.375  -1.369  -1.288  -1.141  -1.109  -1.011  -1.055  -1.049  -0.946
261   A         0.747   0.714   0.762   0.655   0.590   0.642   0.433   0.367   0.412
262   S        -0.102  -0.097  -0.015  -0.352  -0.339  -0.222  -0.417  -0.410  -0.302
263   T        -0.526  -0.558  -0.498  -0.599  -0.642  -0.549  -0.629  -0.661  -0.577
264   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
265   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
266   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
267   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
268   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
269   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
270   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
271   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
272   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
273   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
274   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
275   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
276   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
277   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
278   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
279   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
280   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
281   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
282   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
283   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
284   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
285   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
286   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
287   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
288   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
289   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
290   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
291   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
292   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
293   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
294   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
295   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
296   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
297   S        -0.203  -0.199  -0.342  -0.313  -0.309  -0.496  -0.209  -0.202  -0.382
298   N        -0.430  -0.437  -0.438  -0.348  -0.359  -0.342  -0.521  -0.530  -0.513
299   P        -0.930  -0.927  -0.900  -0.932  -0.941  -0.868  -0.833  -0.829  -0.772
300   A        -1.658  -1.656  -1.570  -1.459  -1.463  -1.329  -1.146  -1.143  -1.038
301   E         0.160   0.136   0.112   0.132   0.093   0.046  -0.053  -0.086  -0.129
302   R        -0.203  -0.176  -0.340  -0.255  -0.222  -0.413  -0.209  -0.174  -0.380
303   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
304   Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
305   A        -0.366  -0.342  -0.412  -0.425  -0.384  -0.526  -0.417  -0.385  -0.469
306   P        -0.930  -0.930  -0.909  -0.914  -0.913  -0.876  -0.833  -0.832  -0.780
307   R         0.453   0.486   0.268   0.323   0.365   0.076   0.416   0.465   0.126
308   L        -0.366  -0.383  -0.406  -0.574  -0.609  -0.635  -0.417  -0.439  -0.463
309   P         1.915   1.918   1.995   1.931   1.934   2.057   2.133   2.137   2.257
310   R        -0.950  -0.909  -0.899  -0.966  -0.891  -0.898  -0.842  -0.799  -0.767
311   R        -0.950  -0.968  -0.913  -1.008  -1.031  -0.922  -0.842  -0.860  -0.781
312   E        -0.526  -0.500  -0.479  -0.617  -0.575  -0.559  -0.629  -0.603  -0.558
313   T        -0.950  -0.964  -0.903  -0.923  -0.971  -0.868  -0.842  -0.855  -0.771
314   S        -0.526  -0.526  -0.481  -0.720  -0.713  -0.658  -0.629  -0.627  -0.559
315   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
316   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
317   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
318   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
319   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
320   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
321   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
322   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
323   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
324   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
325   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
326   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
327   S         0.883   0.903   0.873   0.801   0.840   0.777   0.699   0.736   0.638
328   S        -0.366  -0.358  -0.415  -0.201  -0.186  -0.312  -0.417  -0.407  -0.473
329   A         0.322   0.362   0.205   0.109   0.165  -0.060   0.221   0.280   0.029
330   Y         0.058   0.058   0.074  -0.105  -0.106  -0.109  -0.204  -0.205  -0.179
331   S        -0.526  -0.518  -0.480  -0.847  -0.839  -0.763  -0.629  -0.620  -0.558
332   A         0.058   0.086   0.082  -0.130  -0.091  -0.088  -0.204  -0.170  -0.171
333   D        -0.366  -0.337  -0.422  -0.352  -0.307  -0.445  -0.417  -0.380  -0.482
334   R        -0.950  -0.965  -0.914  -1.214  -1.236  -1.140  -0.842  -0.855  -0.782
335   Y         0.058   0.089   0.065  -0.267  -0.231  -0.231  -0.204  -0.166  -0.194
336   G         1.088   1.060   0.976   1.128   1.090   0.968   1.071   1.022   0.837
337   S        -0.526  -0.506  -0.486  -0.545  -0.512  -0.469  -0.629  -0.608  -0.564
338   S         0.883   0.846   0.864   0.685   0.620   0.610   0.699   0.628   0.618
339   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
340   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
341   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
342   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
343   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
344   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
345   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
346   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
347   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
348   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
349   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
350   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
351   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
352   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
353   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
354   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
355   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
356   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
357   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
358   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
359   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
360   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
361   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
362   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
363   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
364   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
365   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
366   -        -0.022  -0.005   0.028  -0.439  -0.428  -0.359  -0.315  -0.294  -0.244
367   -        -0.022  -0.046   0.018  -0.354  -0.397  -0.291  -0.315  -0.344  -0.258
368   A        -0.430  -0.451  -0.445  -0.358  -0.394  -0.379  -0.521  -0.545  -0.521
369   R        -1.294  -1.306  -1.260  -1.369  -1.380  -1.332  -0.989  -0.998  -0.925
370   Y         1.162   1.160   1.029   1.384   1.385   1.211   1.197   1.193   0.936
371   R        -0.066  -0.061   0.005  -0.504  -0.496  -0.387  -0.365  -0.358  -0.273
372   G        -0.930  -0.934  -0.904  -1.025  -1.026  -0.981  -0.833  -0.836  -0.776
373   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
374   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
375   N        -0.531  -0.529  -0.496  -0.486  -0.488  -0.449  -0.621  -0.618  -0.571
376   R        -1.040  -1.038  -0.954  -1.382  -1.367  -1.251  -0.927  -0.924  -0.818
377   P         0.170   0.148   0.108  -0.023  -0.071  -0.188  -0.009  -0.043  -0.118
378   L        -1.040  -1.038  -0.954  -1.175  -1.180  -1.045  -0.927  -0.924  -0.818
379   L        -0.531  -0.529  -0.496  -0.788  -0.784  -0.759  -0.621  -0.618  -0.571
380   S        -0.531  -0.545  -0.499  -0.645  -0.675  -0.604  -0.621  -0.637  -0.574
381   A        -0.531  -0.529  -0.496  -0.613  -0.611  -0.565  -0.621  -0.618  -0.571
382   A        -0.022  -0.020   0.022  -0.343  -0.350  -0.260  -0.315  -0.312  -0.253
383   T        -0.950  -0.944  -0.918  -0.901  -0.891  -0.845  -0.842  -0.835  -0.785
384   P        -0.366  -0.403  -0.417  -0.308  -0.367  -0.390  -0.417  -0.463  -0.475
385   T        -0.430  -0.427  -0.435  -0.232  -0.230  -0.226  -0.521  -0.521  -0.510
386   A        -0.930  -0.930  -0.909  -0.973  -0.983  -0.924  -0.833  -0.832  -0.780
387   -        -0.531  -0.522  -0.482  -0.635  -0.623  -0.570  -0.621  -0.611  -0.554
388   A        -0.526  -0.533  -0.487  -0.591  -0.600  -0.521  -0.629  -0.635  -0.565
389   V        -1.375  -1.373  -1.288  -1.081  -1.075  -0.952  -1.055  -1.052  -0.946
390   T        -0.366  -0.358  -0.416  -0.471  -0.462  -0.575  -0.417  -0.407  -0.474
391   S         0.322   0.314   0.194   0.305   0.298   0.097   0.221   0.209   0.012
392   V        -0.366  -0.368  -0.406  -0.345  -0.346  -0.402  -0.417  -0.420  -0.463
393   Y         1.915   1.918   1.995   2.045   2.051   2.171   2.133   2.137   2.257
394   K         0.322   0.366   0.222   0.051   0.117  -0.113   0.221   0.287   0.055
395   S         0.817   0.803   0.820   0.653   0.630   0.632   0.572   0.543   0.531
396   R         0.160   0.166   0.115  -0.174  -0.169  -0.228  -0.053  -0.044  -0.122
397   N        -1.294  -1.303  -1.247  -1.313  -1.320  -1.213  -0.989  -0.996  -0.915
398   S        -0.567  -0.572  -0.507  -0.603  -0.605  -0.504  -0.677  -0.681  -0.589
399   R         0.160   0.176   0.128  -0.186  -0.162  -0.220  -0.053  -0.028  -0.100
400   T        -0.930  -0.931  -0.887  -0.967  -0.967  -0.891  -0.833  -0.833  -0.761
401   R        -0.793  -0.790  -0.848  -0.972  -0.974  -1.043  -0.677  -0.673  -0.716
402   E        -0.567  -0.567  -0.507  -0.642  -0.644  -0.563  -0.677  -0.676  -0.590
403   S        -0.203  -0.204  -0.363  -0.374  -0.377  -0.614  -0.209  -0.209  -0.409
404   -         0.006  -0.025   0.023  -0.187  -0.239  -0.169  -0.258  -0.305  -0.247
405   Q        -0.531  -0.553  -0.509  -0.574  -0.612  -0.566  -0.621  -0.647  -0.586
406   P         0.170   0.175   0.116  -0.047  -0.044  -0.131  -0.009  -0.001  -0.106
407   A        -1.040  -1.036  -0.954  -1.044  -1.032  -0.914  -0.927  -0.922  -0.818
408   P        -0.022  -0.017   0.028  -0.209  -0.201  -0.143  -0.315  -0.308  -0.244
409   K        -0.022  -0.018   0.028  -0.339  -0.320  -0.250  -0.315  -0.309  -0.244
410   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
411   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
412   P        -1.294  -1.293  -1.247  -1.432  -1.432  -1.341  -0.989  -0.987  -0.915
413   D        -0.930  -0.917  -0.904  -0.867  -0.839  -0.838  -0.833  -0.820  -0.776
414   Y        -0.203  -0.178  -0.326   0.066   0.106  -0.121  -0.209  -0.176  -0.363
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q00916
Output conservation file - output/Q00916
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
