1     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
2     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
19    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
20    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
21    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
22    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
23    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
24    M         1.860   1.866   1.958   2.181   2.191   2.337   2.088   2.098   2.250
25    S         0.785   0.806   0.670   0.873   0.903   0.716   0.761   0.795   0.544
26    E        -1.001  -1.013  -0.996  -1.007  -1.017  -0.969  -0.897  -0.909  -0.863
27    F        -1.118  -1.116  -1.054  -0.822  -0.824  -0.717  -1.022  -1.018  -0.924
28    K         0.414   0.412   0.464  -0.132  -0.137  -0.052   0.098   0.092   0.158
29    I        -0.373  -0.368  -0.366  -0.419  -0.423  -0.443  -0.503  -0.496  -0.486
30    V        -0.181  -0.173  -0.285   0.110   0.120  -0.038  -0.234  -0.222  -0.373
31    S        -0.181  -0.173  -0.285  -0.049  -0.037  -0.190  -0.234  -0.222  -0.373
32    R         1.860   1.866   1.958   1.883   1.890   2.034   2.088   2.098   2.250
33    K        -1.001  -1.003  -1.007  -1.100  -1.088  -1.132  -0.897  -0.897  -0.874
34    D        -1.001  -0.977  -0.998  -1.135  -1.099  -1.116  -0.897  -0.869  -0.865
35    L         1.860   1.866   1.958   1.976   1.985   2.129   2.088   2.098   2.250
36    Y         0.414   0.406   0.469   0.517   0.501   0.594   0.098   0.080   0.166
37    N         0.414   0.412   0.464   0.350   0.341   0.407   0.098   0.092   0.158
38    E        -0.181  -0.177  -0.274  -0.164  -0.149  -0.327  -0.234  -0.228  -0.357
39    G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
40    E         0.785   0.754   0.657   0.661   0.622   0.486   0.761   0.709   0.521
41    G        -1.001  -1.003  -1.007  -0.773  -0.775  -0.752  -0.897  -0.897  -0.874
42    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
43    G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
44    E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
45    D        -0.406  -0.421  -0.375  -0.628  -0.647  -0.568  -0.566  -0.581  -0.505
46    Y        -0.181  -0.212  -0.283   0.144   0.096  -0.016  -0.234  -0.277  -0.370
47    D        -0.181  -0.212  -0.283  -0.006  -0.052  -0.143  -0.234  -0.277  -0.370
48    S        -0.181  -0.212  -0.283  -0.052  -0.097  -0.192  -0.234  -0.277  -0.370
49    N        -1.001  -1.026  -0.995  -0.877  -0.919  -0.882  -0.897  -0.922  -0.862
50    S        -1.597  -1.595  -1.539  -1.488  -1.487  -1.394  -1.229  -1.226  -1.135
51    S        -0.406  -0.408  -0.374  -0.459  -0.460  -0.392  -0.566  -0.566  -0.504
52    S        -0.500  -0.496  -0.429  -0.565  -0.557  -0.456  -0.676  -0.670  -0.571
53    K        -0.500  -0.496  -0.429  -0.751  -0.730  -0.645  -0.676  -0.670  -0.571
54    N        -0.500  -0.496  -0.429  -0.441  -0.439  -0.329  -0.676  -0.670  -0.571
55    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
56    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
57    E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
58    H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
59    V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
60    E        -0.500  -0.496  -0.429  -0.800  -0.788  -0.694  -0.676  -0.671  -0.571
61    V         0.493   0.478   0.520   0.589   0.564   0.628   0.245   0.217   0.265
62    L        -0.373  -0.350  -0.348  -0.195  -0.162  -0.154  -0.503  -0.470  -0.460
63    V        -0.373  -0.378  -0.364  -0.157  -0.172  -0.137  -0.503  -0.509  -0.483
64    P         1.860   1.866   1.958   2.044   2.054   2.197   2.088   2.098   2.250
65    P        -0.373  -0.350  -0.348  -0.640  -0.609  -0.584  -0.503  -0.470  -0.460
66    T        -0.373  -0.350  -0.348  -0.246  -0.212  -0.203  -0.503  -0.470  -0.460
67    E         0.414   0.406   0.469   0.031   0.018   0.109   0.098   0.080   0.166
68    F         0.785   0.754   0.657   1.064   1.020   0.869   0.761   0.709   0.521
69    E         0.785   0.781   0.677   0.619   0.616   0.452   0.761   0.755   0.556
70    F        -0.181  -0.192  -0.260   0.139   0.123   0.021  -0.234  -0.249  -0.337
71    V         0.785   0.779   0.666   0.889   0.877   0.644   0.761   0.752   0.536
72    E        -0.181  -0.212  -0.283  -0.303  -0.347  -0.448  -0.234  -0.277  -0.370
73    V         1.860   1.866   1.958   2.020   2.027   2.173   2.088   2.098   2.250
74    E         0.785   0.754   0.657   0.649   0.611   0.468   0.761   0.709   0.521
75    R        -1.597  -1.595  -1.539  -1.413  -1.410  -1.318  -1.229  -1.226  -1.135
76    T        -1.001  -0.977  -0.998  -0.750  -0.712  -0.741  -0.897  -0.869  -0.865
77    D        -1.001  -1.013  -0.996  -0.947  -0.966  -0.942  -0.897  -0.909  -0.863
78    S        -0.181  -0.156  -0.268  -0.313  -0.273  -0.439  -0.234  -0.198  -0.348
79    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
80    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
81    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
82    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
83    D         0.493   0.490   0.520   0.204   0.193   0.198   0.245   0.239   0.265
84    L        -0.500  -0.498  -0.429  -0.450  -0.446  -0.338  -0.676  -0.672  -0.571
85    K        -0.500  -0.498  -0.429  -0.705  -0.693  -0.598  -0.676  -0.672  -0.571
86    E         0.652   0.622   0.591   0.321   0.268   0.157   0.533   0.480   0.398
87    S        -0.181  -0.192  -0.260  -0.115  -0.133  -0.239  -0.234  -0.249  -0.337
88    N        -0.181  -0.193  -0.282  -0.118  -0.137  -0.340  -0.234  -0.251  -0.368
89    N        -1.001  -1.014  -1.008  -1.020  -1.051  -1.074  -0.897  -0.910  -0.875
90    S        -1.001  -0.990  -0.988  -0.955  -0.937  -0.956  -0.897  -0.883  -0.854
91    A        -1.001  -0.990  -0.988  -0.712  -0.700  -0.690  -0.897  -0.884  -0.854
92    H        -1.597  -1.595  -1.539  -1.329  -1.344  -1.233  -1.229  -1.226  -1.135
93    E        -0.181  -0.214  -0.281  -0.315  -0.360  -0.461  -0.234  -0.279  -0.367
94    Q        -1.001  -0.977  -0.998  -0.930  -0.898  -0.926  -0.897  -0.869  -0.865
95    K        -1.597  -1.595  -1.539  -1.533  -1.515  -1.440  -1.229  -1.226  -1.135
96    E        -0.406  -0.406  -0.370  -0.518  -0.506  -0.441  -0.566  -0.564  -0.499
97    E        -0.406  -0.407  -0.377  -0.518  -0.508  -0.458  -0.566  -0.565  -0.508
98    K        -1.001  -0.976  -0.981  -1.102  -1.049  -1.084  -0.897  -0.868  -0.846
99    Q        -1.001  -1.003  -1.007  -0.804  -0.809  -0.795  -0.897  -0.897  -0.874
100   E        -0.181  -0.173  -0.285  -0.318  -0.305  -0.471  -0.234  -0.222  -0.373
101   E         1.860   1.866   1.958   1.646   1.659   1.793   2.088   2.098   2.250
102   F         0.785   0.781   0.677   1.092   1.089   0.944   0.761   0.755   0.556
103   E        -0.181  -0.192  -0.260  -0.318  -0.334  -0.433  -0.234  -0.249  -0.337
104   F         1.860   1.866   1.958   2.077   2.087   2.231   2.088   2.098   2.250
105   P         1.860   1.866   1.958   2.048   2.058   2.202   2.088   2.098   2.250
106   L         1.860   1.866   1.958   1.976   1.985   2.129   2.088   2.098   2.250
107   F         1.860   1.866   1.958   2.077   2.087   2.231   2.088   2.098   2.250
108   S         0.414   0.420   0.473   0.258   0.265   0.343   0.098   0.107   0.176
109   F         0.414   0.420   0.473   0.443   0.451   0.524   0.098   0.107   0.176
110   G         0.652   0.630   0.589   0.848   0.814   0.743   0.533   0.493   0.395
111   V        -1.118  -1.116  -1.054  -0.851  -0.848  -0.746  -1.022  -1.018  -0.924
112   V        -1.118  -1.116  -1.054  -0.942  -0.945  -0.839  -1.022  -1.018  -0.924
113   E         0.371   0.375   0.454   0.095   0.110   0.231   0.015   0.021   0.137
114   A        -1.118  -1.116  -1.054  -1.163  -1.160  -1.063  -1.022  -1.018  -0.924
115   S         0.652   0.661   0.611   0.631   0.645   0.558   0.533   0.548   0.436
116   T         0.652   0.630   0.589   0.785   0.746   0.655   0.533   0.493   0.395
117   S        -0.500  -0.498  -0.429  -0.436  -0.429  -0.325  -0.676  -0.672  -0.571
118   P         0.493   0.490   0.520   0.584   0.580   0.614   0.245   0.239   0.265
119   A         0.493   0.490   0.520   0.491   0.484   0.523   0.245   0.239   0.265
120   Q        -0.500  -0.498  -0.429  -0.418  -0.415  -0.306  -0.676  -0.672  -0.571
121   E         0.493   0.487   0.518   0.185   0.174   0.207   0.245   0.233   0.261
122   E        -1.118  -1.116  -1.054  -1.180  -1.175  -1.081  -1.022  -1.018  -0.924
123   Q        -1.118  -1.116  -1.054  -1.197  -1.182  -1.099  -1.022  -1.018  -0.924
124   G        -1.118  -1.116  -1.054  -1.291  -1.289  -1.194  -1.022  -1.018  -0.924
125   S        -0.373  -0.355  -0.361  -0.352  -0.327  -0.324  -0.503  -0.478  -0.479
126   S        -0.373  -0.350  -0.348  -0.425  -0.380  -0.410  -0.503  -0.470  -0.460
127   T        -1.118  -1.116  -1.054  -1.120  -1.116  -1.020  -1.022  -1.018  -0.924
128   Q        -0.373  -0.386  -0.376  -0.319  -0.339  -0.317  -0.503  -0.520  -0.499
129   E        -0.373  -0.391  -0.363  -0.621  -0.649  -0.609  -0.503  -0.527  -0.482
130   K        -1.118  -1.116  -1.054  -1.341  -1.345  -1.245  -1.022  -1.018  -0.924
131   D        -1.118  -1.116  -1.054  -1.120  -1.115  -1.020  -1.022  -1.018  -0.924
132   T        -0.373  -0.364  -0.356  -0.397  -0.386  -0.374  -0.503  -0.489  -0.471
133   P        -0.373  -0.364  -0.356  -0.364  -0.348  -0.365  -0.503  -0.489  -0.471
134   Q        -1.001  -0.990  -0.988  -1.189  -1.178  -1.201  -0.897  -0.883  -0.854
135   T        -1.001  -1.026  -0.995  -1.054  -1.116  -1.092  -0.897  -0.922  -0.862
136   E        -1.001  -1.003  -1.007  -1.399  -1.392  -1.392  -0.897  -0.897  -0.874
137   V        -1.597  -1.595  -1.539  -1.472  -1.473  -1.378  -1.229  -1.226  -1.135
138   S        -1.001  -1.013  -0.996  -1.052  -1.065  -1.056  -0.897  -0.909  -0.863
139   L        -0.181  -0.173  -0.285   0.060   0.070  -0.089  -0.234  -0.222  -0.373
140   M         0.785   0.754   0.657   1.183   1.140   0.994   0.761   0.709   0.521
141   K         1.860   1.866   1.958   1.468   1.478   1.612   2.088   2.098   2.250
142   I         0.785   0.827   0.674   1.026   1.082   0.870   0.761   0.830   0.552
143   S         1.860   1.866   1.958   1.859   1.870   2.009   2.088   2.098   2.250
144   L         1.860   1.866   1.958   1.976   1.985   2.129   2.088   2.098   2.250
145   K         0.414   0.427   0.482  -0.007   0.019   0.072   0.098   0.120   0.191
146   E         0.785   0.781   0.677   0.652   0.650   0.502   0.761   0.755   0.556
147   P        -1.001  -1.001  -0.993  -0.837  -0.838  -0.839  -0.897  -0.895  -0.860
148   E         0.414   0.427   0.482   0.073   0.101   0.159   0.098   0.120   0.191
149   E        -0.181  -0.193  -0.282  -0.248  -0.262  -0.371  -0.234  -0.251  -0.368
150   E         0.785   0.754   0.657   0.619   0.577   0.420   0.761   0.709   0.521
151   I        -1.597  -1.595  -1.539  -1.327  -1.335  -1.230  -1.229  -1.226  -1.135
152   I        -0.406  -0.420  -0.373  -0.275  -0.297  -0.217  -0.566  -0.580  -0.503
153   N        -1.118  -1.116  -1.054  -1.130  -1.114  -1.030  -1.022  -1.018  -0.924
154   Q        -0.406  -0.421  -0.386  -0.276  -0.295  -0.230  -0.566  -0.581  -0.518
155   E         0.785   0.754   0.657   0.665   0.626   0.492   0.761   0.709   0.521
156   R         1.860   1.866   1.958   1.883   1.890   2.034   2.088   2.098   2.250
157   P         0.785   0.754   0.657   1.034   0.989   0.838   0.761   0.709   0.521
158   K        -1.001  -1.014  -1.008  -1.399  -1.420  -1.393  -0.897  -0.910  -0.875
159   D        -0.181  -0.177  -0.274  -0.087  -0.078  -0.225  -0.234  -0.228  -0.357
160   Y         0.785   0.779   0.666   1.103   1.097   0.935   0.761   0.752   0.536
161   Y         1.860   1.866   1.958   2.091   2.102   2.246   2.088   2.098   2.250
162   F        -1.001  -1.013  -0.996  -0.470  -0.483  -0.433  -0.897  -0.909  -0.863
163   A         0.785   0.781   0.677   0.964   0.958   0.808   0.761   0.755   0.556
164   S        -1.597  -1.595  -1.539  -1.598  -1.605  -1.506  -1.229  -1.226  -1.135
165   Y         0.785   0.781   0.677   1.078   1.075   0.916   0.761   0.755   0.556
166   S         0.414   0.420   0.473   0.308   0.317   0.398   0.098   0.107   0.176
167   A        -0.406  -0.384  -0.382  -0.647  -0.624  -0.600  -0.566  -0.540  -0.513
168   D        -1.001  -1.003  -1.007  -1.377  -1.374  -1.366  -0.897  -0.897  -0.874
169   Q        -0.406  -0.408  -0.374  -0.288  -0.290  -0.212  -0.566  -0.566  -0.504
170   K         0.414   0.405   0.462  -0.132  -0.146  -0.054   0.098   0.079   0.153
171   L        -1.597  -1.595  -1.539  -1.421  -1.413  -1.326  -1.229  -1.226  -1.135
172   Q        -0.181  -0.212  -0.283   0.064   0.018  -0.093  -0.234  -0.277  -0.370
173   F         0.785   0.781   0.677   1.064   1.060   0.902   0.761   0.755   0.556
174   Q        -0.406  -0.395  -0.378  -0.383  -0.370  -0.324  -0.566  -0.552  -0.508
175   Q        -1.001  -1.013  -0.996  -0.769  -0.790  -0.759  -0.897  -0.909  -0.863
176   S        -0.406  -0.408  -0.377  -0.341  -0.342  -0.262  -0.566  -0.567  -0.508
177   S         0.785   0.827   0.674   0.927   0.986   0.748   0.761   0.830   0.552
178   I        -0.181  -0.155  -0.266   0.087   0.122  -0.039  -0.234  -0.196  -0.346
179   D        -0.406  -0.384  -0.369  -0.407  -0.380  -0.348  -0.566  -0.540  -0.498
180   Y        -0.406  -0.408  -0.377  -0.318  -0.324  -0.276  -0.566  -0.567  -0.508
181   D         1.860   1.866   1.958   1.893   1.902   2.044   2.088   2.098   2.250
182   V         0.414   0.418   0.469   0.318   0.320   0.398   0.098   0.103   0.167
183   I         1.860   1.866   1.958   2.048   2.060   2.202   2.088   2.098   2.250
184   I        -1.001  -1.003  -1.007  -0.618  -0.622  -0.619  -0.897  -0.897  -0.874
185   Q        -1.001  -1.013  -0.996  -0.965  -0.995  -0.983  -0.897  -0.909  -0.863
186   E        -0.406  -0.421  -0.386  -0.513  -0.523  -0.457  -0.566  -0.581  -0.518
187   S        -1.597  -1.595  -1.539  -1.449  -1.446  -1.354  -1.229  -1.226  -1.135
188   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
189   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
190   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
191   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
192   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
193   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
194   D        -1.001  -0.990  -0.988  -1.014  -0.995  -0.969  -0.897  -0.883  -0.854
195   L        -0.406  -0.408  -0.380  -0.231  -0.232  -0.166  -0.566  -0.566  -0.510
196   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
197   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
198   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
199   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
200   R        -0.181  -0.214  -0.281  -0.020  -0.070  -0.155  -0.234  -0.279  -0.367
201   I        -0.406  -0.384  -0.382  -0.333  -0.304  -0.277  -0.566  -0.540  -0.513
202   R        -1.001  -0.977  -0.998  -0.663  -0.623  -0.655  -0.897  -0.869  -0.865
203   D        -1.001  -0.990  -0.988  -0.953  -0.925  -0.953  -0.897  -0.884  -0.854
204   K        -0.406  -0.384  -0.382  -0.405  -0.365  -0.399  -0.566  -0.540  -0.513
205   W         1.860   1.866   1.958   2.260   2.270   2.417   2.088   2.098   2.250
206   P        -0.500  -0.497  -0.429  -0.755  -0.752  -0.649  -0.676  -0.672  -0.571
207   Y        -0.500  -0.497  -0.429  -0.648  -0.642  -0.539  -0.676  -0.672  -0.571
208   C         0.493   0.511   0.515   0.708   0.735   0.749   0.245   0.278   0.256
209   Q         0.493   0.511   0.515   0.432   0.460   0.458   0.245   0.278   0.256
210   G         1.860   1.866   1.958   2.020   2.029   2.174   2.088   2.098   2.250
211   R         0.785   0.827   0.674   0.437   0.496   0.267   0.761   0.830   0.552
212   I        -0.406  -0.384  -0.382  -0.110  -0.086  -0.062  -0.566  -0.540  -0.513
213   I         0.785   0.779   0.666   1.036   1.031   0.856   0.761   0.752   0.536
214   D         0.785   0.779   0.666   0.894   0.885   0.722   0.761   0.752   0.536
215   L         0.414   0.406   0.469   0.388   0.369   0.465   0.098   0.080   0.166
216   Y        -1.597  -1.595  -1.539  -1.308  -1.312  -1.211  -1.229  -1.226  -1.135
217   K        -0.406  -0.406  -0.370  -1.004  -0.995  -0.940  -0.566  -0.564  -0.499
218   H         0.414   0.418   0.469   0.592   0.598   0.681   0.098   0.103   0.167
219   N         1.860   1.866   1.958   2.015   2.024   2.168   2.088   2.098   2.250
220   A        -0.406  -0.395  -0.378  -0.422  -0.414  -0.368  -0.566  -0.552  -0.508
221   R        -1.001  -0.976  -0.981  -1.362  -1.324  -1.321  -0.897  -0.868  -0.846
222   I         0.414   0.412   0.464   0.449   0.443   0.515   0.098   0.092   0.158
223   E        -0.181  -0.212  -0.283  -0.233  -0.270  -0.354  -0.234  -0.277  -0.370
224   L        -1.597  -1.595  -1.539  -1.351  -1.351  -1.255  -1.229  -1.226  -1.135
225   E         0.785   0.781   0.677   0.651   0.649   0.500   0.761   0.755   0.556
226   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
227   Q        -0.181  -0.192  -0.260  -0.100  -0.119  -0.268  -0.234  -0.249  -0.337
228   Q        -1.597  -1.595  -1.539  -1.519  -1.525  -1.426  -1.229  -1.226  -1.135
229   K        -1.597  -1.595  -1.539  -1.411  -1.397  -1.316  -1.229  -1.226  -1.135
230   E        -0.406  -0.421  -0.386  -0.937  -0.949  -0.879  -0.566  -0.581  -0.518
231   L        -1.597  -1.595  -1.539  -1.195  -1.202  -1.096  -1.229  -1.226  -1.135
232   K         0.785   0.754   0.657   0.529   0.492   0.384   0.761   0.709   0.521
233   I        -1.597  -1.595  -1.539  -1.056  -1.056  -0.954  -1.229  -1.226  -1.135
234   K         0.414   0.405   0.462  -0.132  -0.146  -0.054   0.098   0.079   0.153
235   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
236   K         0.414   0.412   0.464  -0.132  -0.137  -0.052   0.098   0.092   0.158
237   R        -0.406  -0.421  -0.386  -0.563  -0.598  -0.568  -0.566  -0.581  -0.518
238   R         1.860   1.866   1.958   1.883   1.890   2.034   2.088   2.098   2.250
239   P         0.785   0.806   0.670   1.034   1.064   0.860   0.761   0.795   0.544
240   G         1.860   1.866   1.958   2.068   2.076   2.221   2.088   2.098   2.250
241   Q         0.785   0.827   0.674   0.472   0.530   0.320   0.761   0.830   0.552
242   K         0.785   0.754   0.657   0.437   0.393   0.239   0.761   0.709   0.521
243   Q         0.414   0.420   0.473   0.110   0.122   0.161   0.098   0.107   0.176
244   R         1.860   1.866   1.958   1.883   1.890   2.034   2.088   2.098   2.250
245   A        -1.597  -1.595  -1.539  -1.137  -1.129  -1.037  -1.229  -1.226  -1.135
246   A        -0.181  -0.173  -0.285   0.027   0.035  -0.129  -0.234  -0.222  -0.373
247   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
248   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
249   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
250   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
251   K         0.414   0.427   0.482  -0.007   0.019   0.072   0.098   0.120   0.191
252   K        -1.597  -1.595  -1.539  -1.470  -1.456  -1.375  -1.229  -1.226  -1.135
253   L        -0.406  -0.421  -0.386  -0.331  -0.349  -0.268  -0.566  -0.581  -0.518
254   A        -0.406  -0.384  -0.382  -0.639  -0.606  -0.581  -0.566  -0.540  -0.513
255   L        -0.181  -0.212  -0.283  -0.167  -0.229  -0.395  -0.234  -0.277  -0.370
256   E         0.785   0.781   0.677   0.510   0.507   0.287   0.761   0.755   0.556
257   R         0.785   0.779   0.666   0.752   0.739   0.507   0.761   0.752   0.536
258   T        -1.597  -1.595  -1.539  -1.651  -1.657  -1.560  -1.229  -1.226  -1.135
259   K         0.785   0.754   0.657   0.440   0.396   0.244   0.761   0.709   0.521
260   E        -1.001  -1.014  -1.008  -0.936  -0.950  -0.899  -0.897  -0.910  -0.875
261   R        -0.181  -0.173  -0.285  -0.248  -0.241  -0.471  -0.234  -0.222  -0.373
262   D        -0.181  -0.155  -0.266  -0.607  -0.568  -0.761  -0.234  -0.196  -0.346
263   T        -1.597  -1.595  -1.539  -1.651  -1.644  -1.560  -1.229  -1.226  -1.135
264   K        -1.001  -1.014  -1.008  -1.362  -1.382  -1.350  -0.897  -0.910  -0.875
265   A        -1.001  -0.977  -0.998  -0.967  -0.934  -0.969  -0.897  -0.869  -0.865
266   R        -1.001  -1.003  -0.991  -1.460  -1.465  -1.443  -0.897  -0.898  -0.857
267   E         0.785   0.779   0.666   0.510   0.504   0.265   0.761   0.752   0.536
268   I        -0.406  -0.396  -0.373  -0.231  -0.219  -0.159  -0.566  -0.553  -0.503
269   K         0.785   0.806   0.670   0.440   0.470   0.264   0.761   0.795   0.544
270   K         0.785   0.806   0.670   0.460   0.489   0.295   0.761   0.795   0.544
271   Q        -0.406  -0.395  -0.373  -0.499  -0.479  -0.476  -0.566  -0.552  -0.503
272   L        -1.001  -1.001  -0.993  -0.702  -0.703  -0.675  -0.897  -0.895  -0.860
273   K         1.860   1.866   1.958   1.468   1.478   1.612   2.088   2.098   2.250
274   K         1.860   1.866   1.958   1.468   1.478   1.612   2.088   2.098   2.250
275   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
276   K         0.414   0.420   0.473   0.058   0.065   0.165   0.098   0.108   0.175
277   F         1.860   1.866   1.958   2.077   2.087   2.231   2.088   2.098   2.250
278   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
279   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
280   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
281   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
282   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
283   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
284   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
285   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
286   H         0.785   0.779   0.666   1.206   1.199   1.028   0.761   0.752   0.536
287   K         0.785   0.779   0.666   0.472   0.466   0.307   0.761   0.752   0.536
288   R         1.860   1.866   1.958   1.883   1.890   2.034   2.088   2.098   2.250
289   G         0.785   0.779   0.666   1.063   1.055   0.887   0.761   0.752   0.536
290   G         1.860   1.866   1.958   2.068   2.076   2.221   2.088   2.098   2.250
291   K         1.860   1.866   1.958   1.468   1.478   1.612   2.088   2.098   2.250
292   K         0.785   0.779   0.666   0.488   0.482   0.332   0.761   0.752   0.536
293   N        -0.181  -0.173  -0.285   0.106   0.113  -0.042  -0.234  -0.222  -0.373
294   K         1.860   1.866   1.958   1.468   1.478   1.612   2.088   2.098   2.250
295   K         0.785   0.779   0.666   0.482   0.477   0.324   0.761   0.752   0.536
296   K        -0.181  -0.173  -0.285  -0.426  -0.412  -0.546  -0.234  -0.222  -0.373
297   V         0.785   0.827   0.674   0.967   1.022   0.808   0.761   0.830   0.552
298   P        -1.118  -1.117  -1.054  -0.965  -0.967  -0.862  -1.022  -1.019  -0.924
299   L        -1.001  -0.977  -0.998  -0.672  -0.637  -0.660  -0.897  -0.869  -0.865
300   N        -1.001  -1.001  -0.993  -0.999  -1.004  -1.017  -0.897  -0.895  -0.860
301   P        -1.001  -1.001  -0.993  -0.906  -0.909  -0.916  -0.897  -0.895  -0.860
302   L        -0.373  -0.383  -0.361  -0.262  -0.279  -0.239  -0.503  -0.517  -0.479
303   A         0.371   0.375   0.452   0.310   0.315   0.435   0.015   0.020   0.134
304   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
305   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
306   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
307   S        -0.181  -0.214  -0.281  -0.066  -0.113  -0.207  -0.234  -0.279  -0.367
308   T        -0.181  -0.177  -0.274  -0.406  -0.400  -0.506  -0.234  -0.228  -0.357
309   P         0.785   0.754   0.657   1.008   0.963   0.797   0.761   0.709   0.521
310   K         1.860   1.866   1.958   1.468   1.478   1.612   2.088   2.098   2.250
311   F        -0.406  -0.421  -0.386  -0.206  -0.229  -0.168  -0.566  -0.581  -0.518
312   R         0.785   0.754   0.657   0.752   0.696   0.489   0.761   0.709   0.521
313   T         0.785   0.754   0.657   1.039   0.993   0.843   0.761   0.709   0.521
314   E         0.785   0.754   0.657   0.510   0.461   0.247   0.761   0.709   0.521
315   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P53952
Output conservation file - output/P53952
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
