1     M         1.083   1.115   1.185   1.338   1.383   1.468   1.154   1.200   1.303
2     L        -0.374  -0.295  -0.126  -0.825  -0.693  -0.401  -0.782  -0.660  -0.402
3     R         1.083   1.115   1.185   0.926   0.984   1.111   1.154   1.200   1.303
4     R        -0.307  -0.251  -0.120  -0.692  -0.606  -0.384  -0.661  -0.579  -0.390
5     Q         0.291   0.075  -0.022   0.505   0.232   0.028   0.307  -0.025  -0.217
6     A         0.291   0.075  -0.022   0.434   0.135  -0.059   0.307  -0.025  -0.217
7     R         1.083   1.115   1.185   0.926   0.984   1.111   1.154   1.200   1.303
8     E         0.291   0.180  -0.010   0.344   0.217  -0.065   0.307   0.140  -0.197
9     R         1.083   1.115   1.185   0.926   0.984   1.111   1.154   1.200   1.303
10    R         1.083   1.115   1.185   0.926   0.984   1.111   1.154   1.200   1.303
11    E        -0.463  -0.769  -0.828  -0.333  -0.751  -0.859  -0.419  -0.819  -0.887
12    Y         0.291   0.075  -0.022   0.597   0.309   0.121   0.307  -0.025  -0.217
13    L         0.291   0.075  -0.022   0.128  -0.143  -0.268   0.307  -0.025  -0.217
14    Y         1.083   1.115   1.185   1.268   1.312   1.408   1.154   1.200   1.303
15    R         0.291   0.075  -0.022   0.234  -0.054  -0.212   0.307  -0.025  -0.217
16    K        -0.099  -0.236  -0.122  -0.247  -0.540  -0.377  -0.298  -0.553  -0.394
17    A        -0.809  -0.887  -0.842  -0.748  -0.837  -0.817  -0.903  -0.974  -0.908
18    Q        -0.374  -0.295  -0.126  -0.788  -0.650  -0.379  -0.782  -0.660  -0.402
19    E        -0.809  -0.795  -0.832  -0.879  -0.858  -0.959  -0.903  -0.856  -0.895
20    L         1.083   1.115   1.185   0.808   0.869   1.009   1.154   1.200   1.303
21    Q         0.291   0.180  -0.010   0.493   0.366   0.017   0.307   0.140  -0.197
22    D         0.291   0.443   0.013   0.327   0.521  -0.068   0.307   0.516  -0.157
23    S        -0.965  -0.792  -0.841  -1.086  -0.860  -0.859  -1.145  -0.951  -0.910
24    Q        -2.057  -2.072  -1.854  -1.917  -1.980  -1.684  -1.750  -1.714  -1.420
25    L        -0.463  -0.483  -0.790  -0.575  -0.603  -1.034  -0.419  -0.451  -0.838
26    Q        -2.057  -2.072  -1.854  -1.803  -1.822  -1.535  -1.750  -1.714  -1.420
27    Q        -0.374  -0.251  -0.107  -0.639  -0.443  -0.223  -0.782  -0.580  -0.367
28    K         1.083   1.115   1.185   1.047   1.098   1.216   1.154   1.200   1.303
29    R         1.083   1.115   1.185   0.926   0.984   1.111   1.154   1.200   1.303
30    Q        -0.463  -0.769  -0.828  -0.198  -0.647  -0.822  -0.419  -0.819  -0.887
31    I        -1.556  -1.640  -1.417  -1.470  -1.568  -1.273  -1.508  -1.530  -1.236
32    I        -0.307  -0.102  -0.064  -0.747  -0.414  -0.334  -0.661  -0.318  -0.290
33    K        -0.099  -0.236  -0.122  -0.247  -0.540  -0.377  -0.298  -0.553  -0.394
34    Q        -1.556  -1.640  -1.417  -1.494  -1.612  -1.313  -1.508  -1.530  -1.236
35    A         1.083   1.115   1.185   1.129   1.181   1.288   1.154   1.200   1.303
36    L         1.083   1.115   1.185   0.808   0.869   1.009   1.154   1.200   1.303
37    A         0.291   0.075  -0.022   0.433   0.133  -0.061   0.307  -0.025  -0.217
38    Q        -0.965  -0.979  -0.844  -1.036  -1.001  -0.814  -1.145  -1.101  -0.909
39    G         0.291   0.075  -0.022   0.516   0.236   0.059   0.307  -0.025  -0.217
40    K         1.083   1.115   1.185   1.047   1.098   1.216   1.154   1.200   1.303
41    P        -0.463  -0.572  -0.795  -0.217  -0.403  -0.773  -0.419  -0.581  -0.845
42    L         1.083   1.115   1.185   0.808   0.869   1.009   1.154   1.200   1.303
43    P        -1.466  -1.594  -1.418  -1.327  -1.509  -1.285  -1.387  -1.479  -1.237
44    K         0.291   0.180  -0.010   0.372   0.237  -0.048   0.307   0.140  -0.197
45    E        -0.099  -0.158  -0.115  -0.230  -0.346  -0.298  -0.298  -0.415  -0.381
46    L        -0.809  -0.689  -0.831  -1.057  -0.889  -1.045  -0.903  -0.753  -0.896
47    A         0.291   0.075  -0.022   0.457   0.180   0.006   0.307  -0.025  -0.217
48    E        -0.463  -0.483  -0.790  -0.357  -0.393  -0.855  -0.419  -0.451  -0.838
49    D         1.083   1.115   1.185   1.073   1.122   1.238   1.154   1.200   1.303
50    E        -0.809  -0.980  -0.858  -0.887  -1.157  -0.983  -0.903  -1.103  -0.929
51    S        -1.556  -1.346  -1.385  -1.575  -1.288  -1.322  -1.508  -1.281  -1.207
52    L         1.083   1.115   1.185   0.808   0.869   1.009   1.154   1.200   1.303
53    Q        -0.099  -0.097  -0.102  -0.112  -0.115  -0.228  -0.298  -0.309  -0.359
54    K         0.291   0.413   0.014   0.338   0.497  -0.096   0.307   0.475  -0.156
55    D         0.291   0.407   0.009   0.390   0.536  -0.015   0.307   0.468  -0.164
56    F        -0.463  -0.577  -0.803  -0.126  -0.281  -0.632  -0.419  -0.586  -0.855
57    R        -2.559  -2.433  -2.201  -2.447  -2.299  -1.934  -1.992  -1.844  -1.537
58    Y         1.083   1.115   1.185   1.268   1.312   1.408   1.154   1.200   1.303
59    D         1.083   1.115   1.185   1.073   1.122   1.238   1.154   1.200   1.303
60    Q        -0.809  -0.744  -0.811  -0.839  -0.725  -0.851  -0.903  -0.785  -0.867
61    S         1.083   1.115   1.185   1.049   1.108   1.218   1.154   1.200   1.303
62    L        -2.559  -2.177  -2.182  -2.579  -2.076  -2.033  -1.992  -1.650  -1.524
63    K        -1.466  -1.453  -1.397  -1.309  -1.324  -1.267  -1.387  -1.365  -1.218
64    E        -2.195  -2.042  -1.839  -2.209  -1.985  -1.688  -1.871  -1.687  -1.409
65    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
66    E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
67    E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
68    A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
69    D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
70    D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
71    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
72    Q        -2.057  -2.009  -1.841  -1.903  -1.838  -1.578  -1.750  -1.664  -1.411
73    V        -0.809  -0.829  -0.822  -0.826  -0.868  -0.936  -0.903  -0.897  -0.881
74    D         1.083   1.115   1.185   1.073   1.122   1.238   1.154   1.200   1.303
75    D         1.083   1.115   1.185   1.073   1.122   1.238   1.154   1.200   1.303
76    E         1.083   1.115   1.185   1.016   1.070   1.189   1.154   1.200   1.303
77    Y         1.083   1.115   1.185   1.268   1.312   1.408   1.154   1.200   1.303
78    A        -1.173  -1.176  -1.360  -0.989  -1.004  -1.313  -1.024  -1.040  -1.178
79    A        -0.809  -0.941  -0.855  -0.830  -1.085  -0.990  -0.903  -1.066  -0.927
80    T        -1.466  -1.098  -1.364  -1.596  -1.090  -1.366  -1.387  -0.950  -1.182
81    S         1.083   1.115   1.185   1.036   1.083   1.207   1.154   1.200   1.303
82    G         1.083   1.115   1.185   1.185   1.237   1.336   1.154   1.200   1.303
83    I        -0.463  -0.769  -0.828  -0.249  -0.708  -0.865  -0.419  -0.819  -0.887
84    M        -2.923  -2.710  -2.495  -2.639  -2.426  -2.068  -2.113  -1.916  -1.619
85    D        -0.374  -0.295  -0.127  -0.723  -0.600  -0.318  -0.782  -0.660  -0.402
86    P         0.291   0.479   0.016   0.484   0.710   0.078   0.307   0.564  -0.152
87    R        -0.307  -0.225  -0.115  -0.649  -0.515  -0.360  -0.661  -0.532  -0.382
88    I        -0.307  -0.219  -0.113  -0.559  -0.414  -0.256  -0.661  -0.521  -0.378
89    I        -1.192  -1.000  -0.866  -1.591  -1.330  -1.105  -1.387  -1.128  -0.936
90    V        -0.099   0.034  -0.049  -0.204   0.002  -0.146  -0.298  -0.091  -0.265
91    T         1.083   1.115   1.185   1.114   1.160   1.274   1.154   1.200   1.303
92    T         1.083   1.115   1.185   1.114   1.160   1.274   1.154   1.200   1.303
93    S         1.083   1.115   1.185   1.049   1.108   1.218   1.154   1.200   1.303
94    R         1.083   1.115   1.185   0.926   0.984   1.111   1.154   1.200   1.303
95    D        -0.463  -0.590  -0.798  -0.282  -0.489  -0.785  -0.419  -0.601  -0.849
96    P         1.083   1.115   1.185   1.165   1.213   1.318   1.154   1.200   1.303
97    S         1.083   1.115   1.185   1.049   1.108   1.218   1.154   1.200   1.303
98    T        -1.192  -1.022  -0.862  -1.442  -1.177  -0.944  -1.387  -1.158  -0.932
99    R        -0.099   0.034  -0.049  -0.326  -0.117  -0.260  -0.298  -0.091  -0.265
100   L         1.083   1.115   1.185   0.808   0.869   1.009   1.154   1.200   1.303
101   S        -1.693  -1.655  -1.419  -1.883  -1.790  -1.438  -1.629  -1.545  -1.238
102   Q         1.083   1.115   1.185   1.185   1.253   1.336   1.154   1.200   1.303
103   F         1.083   1.115   1.185   1.200   1.260   1.349   1.154   1.200   1.303
104   A        -0.307  -0.251  -0.120  -0.510  -0.430  -0.242  -0.661  -0.579  -0.390
105   K         1.083   1.115   1.185   1.047   1.098   1.216   1.154   1.200   1.303
106   E         1.083   1.115   1.185   1.016   1.070   1.189   1.154   1.200   1.303
107   I        -0.099  -0.158  -0.115  -0.129  -0.255  -0.242  -0.298  -0.415  -0.381
108   K        -0.099  -0.236  -0.122  -0.247  -0.540  -0.377  -0.298  -0.553  -0.394
109   L         1.083   1.115   1.185   0.808   0.869   1.009   1.154   1.200   1.303
110   L        -0.099   0.034  -0.049  -0.340  -0.145  -0.218  -0.298  -0.091  -0.265
111   F        -0.463  -0.769  -0.828  -0.200  -0.656  -0.855  -0.419  -0.819  -0.887
112   P         1.083   1.115   1.185   1.165   1.213   1.318   1.154   1.200   1.303
113   N        -0.307  -0.228  -0.120  -0.407  -0.288  -0.152  -0.661  -0.538  -0.390
114   A        -0.307  -0.102  -0.064  -0.538  -0.190  -0.153  -0.661  -0.318  -0.290
115   V        -1.466  -1.453  -1.399  -1.462  -1.417  -1.377  -1.387  -1.347  -1.219
116   R        -0.099   0.034  -0.049  -0.326  -0.117  -0.260  -0.298  -0.091  -0.265
117   L         1.083   1.115   1.185   0.808   0.869   1.009   1.154   1.200   1.303
118   N         1.083   1.115   1.185   1.208   1.258   1.356   1.154   1.200   1.303
119   R         1.083   1.115   1.185   0.926   0.984   1.111   1.154   1.200   1.303
120   G         1.083   1.115   1.185   1.185   1.237   1.336   1.154   1.200   1.303
121   N         0.291   0.407   0.009   0.535   0.681   0.120   0.307   0.468  -0.164
122   Y        -1.173  -1.361  -1.395  -0.798  -1.147  -1.279  -1.024  -1.239  -1.213
123   V        -0.099   0.102  -0.067  -0.204   0.102  -0.178  -0.298   0.017  -0.297
124   M        -1.693  -1.687  -1.424  -1.693  -1.760  -1.397  -1.629  -1.572  -1.242
125   P        -2.422  -2.352  -2.193  -2.080  -2.045  -1.842  -1.871  -1.784  -1.531
126   N        -1.102  -0.982  -0.865  -1.217  -1.071  -0.891  -1.266  -1.113  -0.937
127   L         1.083   1.115   1.185   0.808   0.869   1.009   1.154   1.200   1.303
128   V         1.083   1.115   1.185   1.021   1.079   1.193   1.154   1.200   1.303
129   D        -2.057  -2.055  -1.835  -1.975  -1.980  -1.653  -1.750  -1.697  -1.406
130   A        -0.099   0.034  -0.049  -0.107   0.093  -0.072  -0.298  -0.091  -0.265
131   C        -0.099  -0.236  -0.122   0.173  -0.120  -0.009  -0.298  -0.553  -0.394
132   K        -1.466  -1.418  -1.388  -1.404  -1.369  -1.300  -1.387  -1.305  -1.208
133   K        -1.831  -1.621  -1.427  -2.028  -1.687  -1.421  -1.750  -1.505  -1.245
134   S        -1.466  -1.594  -1.418  -1.418  -1.561  -1.318  -1.387  -1.479  -1.237
135   G        -2.057  -2.072  -1.854  -1.782  -1.821  -1.527  -1.750  -1.714  -1.420
136   T        -2.057  -1.961  -1.836  -2.010  -1.927  -1.761  -1.750  -1.630  -1.407
137   T        -0.374  -0.271  -0.118  -0.668  -0.490  -0.249  -0.782  -0.616  -0.386
138   D         1.083   1.115   1.185   1.073   1.122   1.238   1.154   1.200   1.303
139   L        -1.173  -1.357  -1.390  -1.167  -1.444  -1.392  -1.024  -1.235  -1.208
140   V        -0.374  -0.275  -0.120  -0.671  -0.514  -0.267  -0.782  -0.622  -0.391
141   V        -1.102  -1.100  -0.893  -1.398  -1.424  -1.112  -1.266  -1.255  -0.970
142   L         1.083   1.115   1.185   0.808   0.869   1.009   1.154   1.200   1.303
143   H         1.083   1.115   1.185   1.248   1.295   1.391   1.154   1.200   1.303
144   E         1.083   1.115   1.185   1.016   1.070   1.189   1.154   1.200   1.303
145   H         1.083   1.115   1.185   1.248   1.295   1.391   1.154   1.200   1.303
146   R         1.083   1.115   1.185   0.926   0.984   1.111   1.154   1.200   1.303
147   G         1.083   1.115   1.185   1.185   1.237   1.336   1.154   1.200   1.303
148   V        -0.099  -0.164  -0.112  -0.204  -0.318  -0.254  -0.298  -0.424  -0.376
149   P         1.083   1.115   1.185   1.165   1.213   1.318   1.154   1.200   1.303
150   T        -0.463  -0.572  -0.795  -0.258  -0.439  -0.790  -0.419  -0.581  -0.845
151   S        -0.809  -0.976  -0.860  -0.797  -1.031  -0.866  -0.903  -1.097  -0.932
152   L        -0.099  -0.097  -0.102  -0.340  -0.327  -0.280  -0.298  -0.309  -0.359
153   T         0.291   0.075  -0.022   0.418   0.115  -0.071   0.307  -0.025  -0.217
154   I        -0.374  -0.257  -0.111  -0.671  -0.453  -0.234  -0.782  -0.591  -0.375
155   S         1.083   1.115   1.185   1.049   1.108   1.218   1.154   1.200   1.303
156   H         1.083   1.115   1.185   1.248   1.295   1.391   1.154   1.200   1.303
157   F         0.291   0.075  -0.022   0.476   0.161  -0.084   0.307  -0.025  -0.217
158   P         1.083   1.115   1.185   1.165   1.213   1.318   1.154   1.200   1.303
159   H        -0.099  -0.132  -0.108   0.056  -0.013  -0.019  -0.298  -0.369  -0.370
160   G         1.083   1.115   1.185   1.185   1.237   1.336   1.154   1.200   1.303
161   P         1.083   1.115   1.185   1.165   1.213   1.318   1.154   1.200   1.303
162   T         0.291   0.393   0.012   0.422   0.551   0.001   0.307   0.448  -0.159
163   A        -0.809  -0.839  -0.856  -0.850  -1.036  -1.010  -0.903  -0.983  -0.928
164   Q        -2.559  -2.452  -2.201  -2.139  -2.011  -1.660  -1.992  -1.854  -1.537
165   F         0.291   0.180  -0.010   0.505   0.369   0.019   0.307   0.140  -0.197
166   S        -0.307  -0.149  -0.097  -0.547  -0.278  -0.219  -0.661  -0.398  -0.349
167   L         1.083   1.115   1.185   0.808   0.869   1.009   1.154   1.200   1.303
168   H         1.083   1.115   1.185   1.248   1.295   1.391   1.154   1.200   1.303
169   N         1.083   1.115   1.185   1.208   1.258   1.356   1.154   1.200   1.303
170   V         1.083   1.115   1.185   1.021   1.079   1.193   1.154   1.200   1.303
171   V        -0.099   0.034  -0.049  -0.233  -0.024  -0.186  -0.298  -0.091  -0.265
172   M         0.291   0.443   0.013   0.160   0.351  -0.135   0.307   0.516  -0.157
173   R         1.083   1.115   1.185   0.926   0.984   1.111   1.154   1.200   1.303
174   H         0.291   0.180  -0.010   0.567   0.424   0.098   0.307   0.140  -0.197
175   D         1.083   1.115   1.185   1.073   1.122   1.238   1.154   1.200   1.303
176   I        -0.307  -0.182  -0.103  -0.629  -0.394  -0.327  -0.661  -0.456  -0.361
177   I        -0.809  -0.482  -0.794  -0.816  -0.306  -0.824  -0.903  -0.458  -0.844
178   N        -1.173  -1.122  -1.356  -0.844  -0.801  -1.217  -1.024  -0.963  -1.173
179   A        -2.559  -2.266  -2.173  -2.528  -2.105  -2.011  -1.992  -1.724  -1.519
180   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
181   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
182   G         1.083   1.115   1.185   1.185   1.237   1.336   1.154   1.200   1.303
183   N        -0.099  -0.236  -0.122  -0.031  -0.305  -0.157  -0.298  -0.553  -0.394
184   Q        -1.693  -1.586  -1.417  -1.599  -1.441  -1.221  -1.629  -1.496  -1.236
185   S         1.083   1.115   1.185   1.049   1.108   1.218   1.154   1.200   1.303
186   E         1.083   1.115   1.185   1.016   1.070   1.189   1.154   1.200   1.303
187   V        -0.965  -1.042  -0.865  -1.156  -1.233  -0.955  -1.145  -1.192  -0.937
188   N        -0.965  -0.729  -0.825  -0.835  -0.479  -0.605  -1.145  -0.816  -0.885
189   P         1.083   1.115   1.185   1.165   1.213   1.318   1.154   1.200   1.303
190   H         0.291   0.180  -0.010   0.539   0.385   0.022   0.307   0.140  -0.197
191   L         1.083   1.115   1.185   0.808   0.869   1.009   1.154   1.200   1.303
192   I         0.291   0.393   0.012   0.441   0.575   0.009   0.307   0.448  -0.159
193   F         1.083   1.115   1.185   1.200   1.260   1.349   1.154   1.200   1.303
194   D        -0.374  -0.251  -0.107  -0.723  -0.518  -0.284  -0.782  -0.580  -0.367
195   N         0.291   0.180  -0.010   0.535   0.399   0.087   0.307   0.140  -0.197
196   F         0.291   0.075  -0.022   0.476   0.161  -0.084   0.307  -0.025  -0.217
197   T        -0.463  -0.478  -0.784  -0.239  -0.275  -0.728  -0.419  -0.445  -0.831
198   T        -0.307  -0.276  -0.125  -0.524  -0.500  -0.265  -0.661  -0.625  -0.399
199   A        -2.195  -1.924  -1.837  -2.162  -1.801  -1.664  -1.871  -1.590  -1.408
200   L         1.083   1.115   1.185   0.808   0.869   1.009   1.154   1.200   1.303
201   G         1.083   1.115   1.185   1.185   1.237   1.336   1.154   1.200   1.303
202   K        -0.463  -0.417  -0.779  -0.308  -0.275  -0.774  -0.419  -0.375  -0.825
203   R         1.083   1.115   1.185   0.926   0.984   1.111   1.154   1.200   1.303
204   V         1.083   1.115   1.185   1.021   1.079   1.193   1.154   1.200   1.303
205   V        -0.463  -0.491  -0.789  -0.361  -0.432  -0.872  -0.419  -0.490  -0.837
206   C        -1.556  -1.350  -1.393  -1.482  -1.240  -1.173  -1.508  -1.284  -1.215
207   I         0.291   0.075  -0.022   0.457   0.169  -0.010   0.307  -0.025  -0.217
208   L         0.291   0.393   0.012   0.160   0.297  -0.136   0.307   0.448  -0.159
209   K        -0.463  -0.572  -0.795  -0.306  -0.481  -0.795  -0.419  -0.581  -0.845
210   H        -0.463  -0.514  -0.793  -0.090  -0.201  -0.608  -0.419  -0.515  -0.843
211   L         1.083   1.115   1.185   0.808   0.869   1.009   1.154   1.200   1.303
212   F         1.083   1.115   1.185   1.200   1.260   1.349   1.154   1.200   1.303
213   N         0.291   0.443   0.013   0.496   0.679   0.101   0.307   0.516  -0.157
214   A         0.291   0.443   0.013   0.484   0.670   0.073   0.307   0.516  -0.157
215   G        -0.463  -0.769  -0.828  -0.207  -0.670  -0.845  -0.419  -0.819  -0.887
216   P        -0.965  -0.956  -0.855  -1.077  -1.039  -0.910  -1.145  -1.088  -0.926
217   K         0.291   0.180  -0.010   0.372   0.237  -0.048   0.307   0.140  -0.197
218   K        -0.463  -0.769  -0.828  -0.314  -0.756  -0.867  -0.419  -0.819  -0.887
219   D        -0.463  -0.769  -0.828  -0.270  -0.697  -0.802  -0.419  -0.819  -0.887
220   S        -1.173  -1.288  -1.383  -0.970  -1.183  -1.312  -1.024  -1.170  -1.201
221   E        -1.693  -1.504  -1.417  -1.744  -1.470  -1.340  -1.629  -1.420  -1.236
222   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
223   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
224   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
225   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
226   R         1.083   1.115   1.185   0.926   0.984   1.111   1.154   1.200   1.303
227   V         1.083   1.115   1.185   1.021   1.079   1.193   1.154   1.200   1.303
228   I         0.291   0.075  -0.022   0.441   0.143  -0.053   0.307  -0.025  -0.217
229   T         1.083   1.115   1.185   1.114   1.160   1.274   1.154   1.200   1.303
230   F         1.083   1.115   1.185   1.200   1.260   1.349   1.154   1.200   1.303
231   A        -0.809  -0.735  -0.840  -0.772  -0.696  -0.858  -0.903  -0.818  -0.907
232   N         1.083   1.115   1.185   1.208   1.258   1.356   1.154   1.200   1.303
233   R        -0.965  -1.042  -0.865  -1.137  -1.200  -0.915  -1.145  -1.192  -0.937
234   G        -0.374  -0.251  -0.107  -0.598  -0.408  -0.183  -0.782  -0.580  -0.367
235   D         1.083   1.115   1.185   1.073   1.122   1.238   1.154   1.200   1.303
236   F        -0.809  -0.941  -0.855  -0.618  -0.820  -0.718  -0.903  -1.066  -0.927
237   I         1.083   1.115   1.185   1.137   1.189   1.294   1.154   1.200   1.303
238   S         0.291   0.180  -0.010   0.353   0.216  -0.105   0.307   0.140  -0.197
239   V         0.291   0.075  -0.022   0.351   0.083  -0.073   0.307  -0.025  -0.217
240   R         1.083   1.115   1.185   0.926   0.984   1.111   1.154   1.200   1.303
241   Q        -0.374  -0.251  -0.107  -0.473  -0.254  -0.059  -0.782  -0.580  -0.367
242   H         1.083   1.115   1.185   1.248   1.295   1.391   1.154   1.200   1.303
243   V        -0.463  -0.590  -0.798  -0.291  -0.474  -0.725  -0.419  -0.601  -0.849
244   Y         1.083   1.115   1.185   1.268   1.312   1.408   1.154   1.200   1.303
245   V         0.291   0.075  -0.022   0.341   0.062  -0.102   0.307  -0.025  -0.217
246   R        -0.307  -0.225  -0.115  -0.649  -0.515  -0.360  -0.661  -0.532  -0.382
247   T         1.083   1.115   1.185   1.114   1.160   1.274   1.154   1.200   1.303
248   R        -1.556  -1.643  -1.413  -1.708  -1.783  -1.433  -1.508  -1.534  -1.232
249   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
250   E        -0.965  -0.997  -0.847  -1.151  -1.162  -0.942  -1.145  -1.126  -0.914
251   G        -1.466  -1.526  -1.411  -1.304  -1.415  -1.264  -1.387  -1.431  -1.230
252   V         0.291   0.075  -0.022   0.342   0.064  -0.099   0.307  -0.025  -0.217
253   E         0.291   0.075  -0.022   0.337   0.055  -0.103   0.307  -0.025  -0.217
254   I        -0.463  -0.171  -0.755  -0.502  -0.146  -0.824  -0.419  -0.048  -0.793
255   A        -0.374  -0.251  -0.107  -0.656  -0.453  -0.230  -0.782  -0.580  -0.367
256   E         1.083   1.115   1.185   1.016   1.070   1.189   1.154   1.200   1.303
257   V        -0.463  -0.572  -0.795  -0.327  -0.488  -0.803  -0.419  -0.581  -0.845
258   G         1.083   1.115   1.185   1.185   1.237   1.336   1.154   1.200   1.303
259   P         1.083   1.115   1.185   1.165   1.213   1.318   1.154   1.200   1.303
260   R         1.083   1.115   1.185   0.926   0.984   1.111   1.154   1.200   1.303
261   F         1.083   1.115   1.185   1.200   1.260   1.349   1.154   1.200   1.303
262   E         0.291   0.180  -0.010   0.333   0.198  -0.093   0.307   0.140  -0.197
263   M         1.083   1.115   1.185   1.338   1.383   1.468   1.154   1.200   1.303
264   R        -0.099  -0.236  -0.122  -0.326  -0.579  -0.388  -0.298  -0.553  -0.394
265   L         0.291   0.180  -0.010   0.133   0.009  -0.239   0.307   0.140  -0.197
266   F        -0.307  -0.182  -0.103  -0.334  -0.129  -0.043  -0.661  -0.456  -0.361
267   E        -0.463  -0.483  -0.790  -0.357  -0.393  -0.855  -0.419  -0.451  -0.838
268   L        -0.307  -0.295  -0.125  -0.747  -0.701  -0.393  -0.661  -0.659  -0.399
269   R        -0.809  -0.755  -0.852  -0.947  -0.942  -0.994  -0.903  -0.904  -0.923
270   L         0.291   0.180  -0.010   0.160   0.047  -0.167   0.307   0.140  -0.197
271   G         1.083   1.115   1.185   1.185   1.237   1.336   1.154   1.200   1.303
272   T        -0.099   0.034  -0.049  -0.218  -0.007  -0.215  -0.298  -0.091  -0.265
273   L        -0.463  -0.572  -0.795  -0.554  -0.722  -0.993  -0.419  -0.581  -0.845
274   E        -0.374  -0.251  -0.107  -0.723  -0.503  -0.274  -0.782  -0.580  -0.367
275   N         0.291   0.075  -0.022   0.557   0.288   0.128   0.307  -0.025  -0.217
276   K         0.291   0.075  -0.022   0.351   0.054  -0.125   0.307  -0.025  -0.217
277   D         1.083   1.115   1.185   1.073   1.122   1.238   1.154   1.200   1.303
278   A         0.291   0.393   0.012   0.438   0.571   0.013   0.307   0.448  -0.159
279   D         0.291   0.393   0.012   0.376   0.508  -0.045   0.307   0.448  -0.159
280   V         0.291   0.180  -0.010   0.338   0.207  -0.089   0.307   0.140  -0.197
281   E         1.083   1.115   1.185   1.016   1.070   1.189   1.154   1.200   1.303
282   W         1.083   1.115   1.185   1.414   1.455   1.534   1.154   1.200   1.303
283   Q        -1.173  -1.361  -1.395  -0.849  -1.140  -1.270  -1.024  -1.239  -1.213
284   L        -0.099   0.043  -0.073  -0.340  -0.133  -0.249  -0.298  -0.077  -0.308
285   R        -1.173  -1.361  -1.395  -1.081  -1.386  -1.387  -1.024  -1.239  -1.213
286   R        -1.173  -1.361  -1.395  -1.042  -1.306  -1.308  -1.024  -1.239  -1.213
287   F        -0.099  -0.236  -0.122   0.011  -0.224  -0.074  -0.298  -0.553  -0.394
288   I        -2.057  -2.038  -1.838  -1.846  -1.803  -1.514  -1.750  -1.683  -1.408
289   R         1.083   1.115   1.185   0.926   0.984   1.111   1.154   1.200   1.303
290   T         0.291   0.075  -0.022   0.451   0.171   0.019   0.307  -0.025  -0.217
291   A        -1.173  -1.372  -1.391  -0.893  -1.228  -1.275  -1.024  -1.249  -1.209
292   N        -0.809  -0.755  -0.852  -0.748  -0.814  -0.918  -0.903  -0.904  -0.923
293   K        -0.965  -1.042  -0.855  -1.249  -1.331  -1.020  -1.145  -1.191  -0.926
294   K         0.291   0.075  -0.022   0.351   0.054  -0.125   0.307  -0.025  -0.217
295   D        -0.965  -1.042  -0.865  -1.079  -1.209  -0.954  -1.145  -1.192  -0.937
296   Y         0.291   0.075  -0.022   0.587   0.289   0.093   0.307  -0.025  -0.217
297   L        -0.463  -0.769  -0.828  -0.549  -0.967  -1.025  -0.419  -0.819  -0.887
298   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P53941
Output conservation file - output/P53941
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
