1     M         2.006   2.027   2.155   2.243   2.274   2.477   2.282   2.317   2.546
2     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     -         0.550   0.544   0.396   0.589   0.586   0.365   0.483   0.473   0.216
4     -         0.550   0.531   0.398   0.497   0.470   0.234   0.483   0.453   0.219
5     V        -0.329  -0.317  -0.305  -0.448  -0.437  -0.429  -0.498  -0.490  -0.455
6     R        -1.479  -1.511  -1.429  -1.327  -1.376  -1.268  -1.098  -1.117  -1.009
7     V        -0.409  -0.386  -0.342  -0.546  -0.515  -0.429  -0.597  -0.567  -0.500
8     V        -0.726  -0.776  -0.725  -0.565  -0.645  -0.579  -0.723  -0.765  -0.689
9     I         0.978   0.976   0.968   0.906   0.903   0.839   0.780   0.768   0.679
10    E         0.043  -0.028  -0.143   0.239   0.130  -0.068   0.029  -0.068  -0.226
11    S         1.317   1.295   1.206   1.324   1.301   1.176   1.406   1.365   1.170
12    E        -0.726  -0.710  -0.710  -0.892  -0.885  -0.870  -0.723  -0.710  -0.675
13    L         0.043   0.063  -0.148   0.152   0.183  -0.116   0.029   0.057  -0.232
14    V        -0.726  -0.751  -0.731  -0.638  -0.691  -0.644  -0.723  -0.749  -0.696
15    R         0.224   0.173   0.238   0.053  -0.006   0.093  -0.097  -0.161  -0.070
16    T        -0.409  -0.423  -0.357  -0.556  -0.576  -0.468  -0.597  -0.615  -0.519
17    E         0.978   0.965   0.994   0.760   0.730   0.762   0.780   0.744   0.735
18    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
19    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
20    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
21    K         0.360   0.308   0.280   0.345   0.245   0.198   0.154   0.059   0.010
22    E         0.043  -0.057  -0.169   0.268   0.120  -0.033   0.029  -0.107  -0.261
23    L        -0.212  -0.265  -0.271  -0.212  -0.296  -0.316  -0.347  -0.417  -0.413
24    P        -1.043  -1.083  -1.067  -0.949  -0.999  -0.993  -0.848  -0.884  -0.839
25    N         0.661   0.561   0.443   0.846   0.715   0.525   0.655   0.500   0.293
26    S        -0.290  -0.278  -0.275  -0.378  -0.362  -0.345  -0.472  -0.452  -0.424
27    L        -0.212  -0.265  -0.271  -0.010  -0.105  -0.132  -0.347  -0.417  -0.413
28    K        -0.726  -0.681  -0.703  -0.710  -0.644  -0.686  -0.723  -0.678  -0.667
29    L        -0.409  -0.399  -0.340  -0.548  -0.530  -0.428  -0.597  -0.581  -0.498
30    R        -1.479  -1.446  -1.404  -1.416  -1.372  -1.305  -1.098  -1.068  -0.989
31    Q        -0.409  -0.378  -0.334  -0.440  -0.400  -0.323  -0.597  -0.554  -0.489
32    F         0.661   0.601   0.453   0.739   0.668   0.463   0.655   0.560   0.310
33    K         0.043   0.015  -0.137   0.173   0.135  -0.094   0.029  -0.009  -0.217
34    D        -0.726  -0.747  -0.718  -0.706  -0.752  -0.717  -0.723  -0.742  -0.681
35    R         0.360   0.297   0.280   0.314   0.213   0.185   0.154   0.049   0.009
36    L         0.661   0.647   0.469   0.756   0.743   0.515   0.655   0.633   0.336
37    Y        -0.212  -0.252  -0.274  -0.300  -0.360  -0.371  -0.347  -0.407  -0.415
38    H        -1.163  -1.176  -1.110  -1.093  -1.085  -1.009  -0.973  -0.979  -0.882
39    V        -0.212  -0.265  -0.271  -0.208  -0.294  -0.313  -0.347  -0.417  -0.413
40    T         0.661   0.635   0.464   0.848   0.815   0.553   0.655   0.615   0.328
41    G         2.006   2.027   2.155   1.958   1.985   2.186   2.282   2.317   2.546
42    V         0.224   0.221   0.238   0.069   0.050   0.101  -0.097  -0.109  -0.070
43    E        -0.846  -0.838  -0.778  -0.997  -0.998  -0.895  -0.848  -0.837  -0.743
44    P         0.661   0.660   0.474   0.819   0.821   0.528   0.655   0.654   0.343
45    E        -0.529  -0.524  -0.634  -0.361  -0.366  -0.558  -0.472  -0.467  -0.579
46    D        -0.212  -0.141  -0.246  -0.299  -0.194  -0.333  -0.347  -0.259  -0.377
47    M         0.796   0.780   0.887   0.740   0.709   0.873   0.404   0.357   0.500
48    E        -0.529  -0.469  -0.619  -0.416  -0.343  -0.568  -0.472  -0.404  -0.562
49    I         0.796   0.807   0.893   0.509   0.527   0.637   0.404   0.415   0.514
50    V        -0.726  -0.675  -0.722  -0.562  -0.521  -0.531  -0.723  -0.678  -0.687
51    V        -0.846  -0.811  -0.774  -0.819  -0.794  -0.692  -0.848  -0.813  -0.740
52    K        -0.726  -0.760  -0.729  -0.619  -0.685  -0.643  -0.723  -0.756  -0.694
53    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
54    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
55    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
56    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
57    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
58    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
59    R        -0.726  -0.705  -0.712  -0.673  -0.648  -0.633  -0.723  -0.694  -0.676
60    Q        -1.479  -1.487  -1.414  -1.288  -1.298  -1.197  -1.098  -1.099  -0.997
61    Y        -1.163  -1.149  -1.110  -0.952  -0.928  -0.863  -0.973  -0.958  -0.881
62    D        -0.409  -0.370  -0.343  -0.551  -0.517  -0.437  -0.597  -0.562  -0.502
63    N        -0.726  -0.729  -0.724  -0.744  -0.741  -0.736  -0.723  -0.727  -0.689
64    K        -1.163  -1.197  -1.120  -1.114  -1.170  -1.073  -0.973  -0.994  -0.889
65    E        -0.104  -0.115  -0.205  -0.194  -0.214  -0.366  -0.171  -0.184  -0.309
66    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
67    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
68    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
69    I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
70    Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
71    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
72    T        -0.430  -0.382  -0.362  -0.429  -0.354  -0.336  -0.602  -0.546  -0.515
73    K        -0.430  -0.477  -0.385  -0.576  -0.658  -0.546  -0.602  -0.660  -0.544
74    K        -1.190  -1.169  -1.116  -1.072  -1.037  -0.958  -0.988  -0.966  -0.883
75    G        -1.190  -1.202  -1.125  -1.214  -1.250  -1.120  -0.988  -0.996  -0.892
76    G        -1.190  -1.153  -1.109  -1.290  -1.244  -1.168  -0.988  -0.953  -0.877
77    A         0.258   0.250   0.268   0.249   0.234   0.252  -0.007  -0.009  -0.007
78    Y        -0.466  -0.482  -0.375  -0.541  -0.560  -0.393  -0.661  -0.672  -0.537
79    S        -0.828  -0.867  -0.765  -1.083  -1.135  -0.991  -0.825  -0.856  -0.729
80    N        -0.329  -0.326  -0.296  -0.610  -0.584  -0.554  -0.498  -0.480  -0.437
81    E        -0.691  -0.622  -0.691  -0.839  -0.729  -0.857  -0.661  -0.583  -0.643
82    D        -0.466  -0.451  -0.372  -0.612  -0.581  -0.477  -0.661  -0.642  -0.535
83    E        -1.479  -1.459  -1.406  -1.549  -1.522  -1.458  -1.098  -1.078  -0.991
84    D         0.043   0.120  -0.123   0.186   0.289  -0.013   0.029   0.134  -0.198
85    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
86    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
87    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
88    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
89    A         0.043   0.005  -0.141   0.137   0.085  -0.129   0.029  -0.027  -0.222
90    N        -1.479  -1.511  -1.429  -1.452  -1.493  -1.383  -1.098  -1.117  -1.009
91    F        -1.163  -1.193  -1.108  -1.216  -1.233  -1.125  -0.973  -0.991  -0.880
92    L        -0.409  -0.389  -0.339  -0.440  -0.410  -0.321  -0.597  -0.568  -0.496
93    K        -0.290  -0.290  -0.279  -0.382  -0.381  -0.362  -0.472  -0.465  -0.428
94    G        -0.409  -0.407  -0.351  -0.641  -0.648  -0.551  -0.597  -0.596  -0.511
95    E        -0.726  -0.715  -0.722  -0.688  -0.692  -0.676  -0.723  -0.715  -0.687
96    E        -0.726  -0.761  -0.719  -0.688  -0.743  -0.684  -0.723  -0.752  -0.684
97    E        -1.163  -1.175  -1.107  -1.094  -1.137  -1.014  -0.973  -0.978  -0.879
98    L        -1.163  -1.197  -1.120  -1.038  -1.078  -0.954  -0.973  -0.994  -0.889
99    I        -1.043  -1.105  -1.077  -0.872  -0.969  -0.944  -0.848  -0.905  -0.848
100   V        -0.212  -0.230  -0.251  -0.214  -0.226  -0.278  -0.347  -0.359  -0.385
101   V        -0.726  -0.755  -0.726  -0.541  -0.608  -0.566  -0.723  -0.752  -0.692
102   V         0.978   1.036   1.002   0.857   0.943   0.866   0.780   0.887   0.752
103   T        -0.726  -0.689  -0.706  -0.603  -0.545  -0.563  -0.723  -0.678  -0.668
104   D         2.006   2.027   2.155   1.908   1.942   2.135   2.282   2.317   2.546
105   S        -0.212  -0.153  -0.240  -0.185  -0.101  -0.244  -0.347  -0.278  -0.372
106   N        -0.212  -0.138  -0.246  -0.193  -0.077  -0.263  -0.347  -0.257  -0.377
107   A        -0.529  -0.612  -0.661  -0.354  -0.484  -0.596  -0.472  -0.568  -0.609
108   Q        -0.846  -0.862  -0.774  -0.889  -0.898  -0.778  -0.848  -0.856  -0.740
109   S         0.661   0.676   0.470   0.769   0.798   0.530   0.655   0.678   0.337
110   I        -1.043  -0.991  -1.052  -0.980  -0.897  -1.004  -0.848  -0.795  -0.824
111   S        -1.163  -1.176  -1.110  -1.145  -1.167  -1.067  -0.973  -0.979  -0.882
112   N        -1.043  -1.060  -1.067  -0.810  -0.829  -0.858  -0.848  -0.860  -0.839
113   Q        -0.529  -0.454  -0.628  -0.375  -0.261  -0.567  -0.472  -0.382  -0.572
114   L         0.978   0.997   0.992   0.867   0.898   0.873   0.780   0.810   0.731
115   A        -1.190  -1.226  -1.142  -1.049  -1.106  -0.983  -0.988  -1.015  -0.906
116   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
117   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
118   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
119   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
120   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
121   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
122   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
123   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
124   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
125   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
126   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
127   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
128   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
129   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
130   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
131   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
132   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
133   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
134   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
135   Q        -1.163  -1.196  -1.108  -1.118  -1.147  -1.012  -0.973  -0.994  -0.880
136   A        -1.043  -0.973  -1.036  -0.899  -0.789  -0.921  -0.848  -0.775  -0.809
137   E        -1.163  -1.186  -1.104  -1.209  -1.262  -1.134  -0.973  -0.986  -0.876
138   G        -0.726  -0.710  -0.709  -0.767  -0.760  -0.748  -0.723  -0.704  -0.673
139   I        -1.479  -1.464  -1.415  -1.386  -1.378  -1.290  -1.098  -1.083  -0.998
140   P         0.043   0.104  -0.121   0.089   0.178  -0.158   0.029   0.106  -0.195
141   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
142   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
143   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
144   M        -1.163  -1.195  -1.121  -1.213  -1.228  -1.126  -0.973  -0.992  -0.890
145   E         0.224   0.180   0.238   0.231   0.167   0.247  -0.097  -0.148  -0.069
146   V        -0.726  -0.690  -0.706  -0.772  -0.729  -0.749  -0.723  -0.677  -0.669
147   I        -0.409  -0.422  -0.349  -0.325  -0.319  -0.227  -0.597  -0.602  -0.505
148   S         0.224   0.230   0.250   0.066   0.081   0.126  -0.097  -0.087  -0.051
149   E        -0.212  -0.225  -0.257  -0.280  -0.303  -0.313  -0.347  -0.365  -0.394
150   E         0.043   0.015  -0.137   0.021  -0.022  -0.255   0.029  -0.009  -0.217
151   D         0.105   0.145   0.175  -0.211  -0.140  -0.131  -0.222  -0.162  -0.144
152   Y         2.006   2.027   2.155   2.158   2.188   2.391   2.282   2.317   2.546
153   L         0.043   0.104  -0.121   0.028   0.098  -0.219   0.029   0.106  -0.195
154   R        -0.726  -0.699  -0.715  -0.676  -0.624  -0.658  -0.723  -0.689  -0.678
155   R         0.978   1.002   0.992   0.917   0.951   0.898   0.780   0.818   0.730
156   D        -0.726  -0.698  -0.720  -0.702  -0.686  -0.702  -0.723  -0.700  -0.685
157   Q         0.360   0.320   0.299   0.259   0.218   0.168   0.154   0.104   0.040
158   S         0.978   0.974   0.972   0.860   0.855   0.823   0.780   0.762   0.688
159   V         2.006   2.027   2.155   1.960   1.982   2.189   2.282   2.317   2.546
160   L         1.317   1.331   1.207   1.340   1.364   1.217   1.406   1.428   1.173
161   R        -1.163  -1.099  -1.105  -0.962  -0.892  -0.866  -0.973  -0.917  -0.878
162   W         2.006   2.027   2.155   2.261   2.294   2.496   2.282   2.317   2.546
163   K         2.006   2.027   2.155   1.977   2.010   2.206   2.282   2.317   2.546
164   M        -0.529  -0.558  -0.635  -0.346  -0.376  -0.494  -0.472  -0.508  -0.580
165   A        -1.479  -1.436  -1.404  -1.273  -1.209  -1.166  -1.098  -1.059  -0.989
166   H         0.043  -0.039  -0.154   0.280   0.173  -0.009   0.029  -0.084  -0.241
167   G         0.224   0.174   0.245   0.062  -0.007   0.101  -0.097  -0.159  -0.062
168   Y         1.317   1.249   1.194   1.340   1.261   1.199   1.406   1.286   1.148
169   G         2.006   2.027   2.155   1.958   1.985   2.186   2.282   2.317   2.546
170   R         1.317   1.322   1.210   1.423   1.430   1.284   1.406   1.412   1.179
171   F         2.006   2.027   2.155   2.148   2.182   2.380   2.282   2.317   2.546
172   N         0.796   0.787   0.887   0.504   0.490   0.626   0.404   0.372   0.499
173   A         0.661   0.561   0.443   0.857   0.725   0.544   0.655   0.500   0.293
174   A        -0.726  -0.717  -0.722  -0.808  -0.799  -0.787  -0.723  -0.712  -0.686
175   Q        -0.409  -0.427  -0.350  -0.306  -0.326  -0.210  -0.597  -0.606  -0.509
176   Q        -1.163  -1.168  -1.101  -1.148  -1.146  -1.045  -0.973  -0.971  -0.874
177   S        -0.212  -0.167  -0.241  -0.284  -0.223  -0.339  -0.347  -0.299  -0.374
178   Q        -1.479  -1.458  -1.406  -1.258  -1.216  -1.151  -1.098  -1.076  -0.991
179   R        -1.163  -1.147  -1.107  -1.035  -1.004  -0.968  -0.973  -0.956  -0.879
180   A        -0.212  -0.167  -0.229  -0.226  -0.152  -0.267  -0.347  -0.282  -0.355
181   A        -0.329  -0.321  -0.298  -0.452  -0.446  -0.420  -0.498  -0.491  -0.446
182   L        -1.270  -1.261  -1.163  -1.300  -1.290  -1.142  -1.056  -1.043  -0.923
183   A        -0.848  -0.841  -0.786  -0.905  -0.896  -0.815  -0.834  -0.823  -0.745
184   K        -1.479  -1.446  -1.404  -1.486  -1.450  -1.369  -1.098  -1.068  -0.989
185   Q        -1.043  -0.991  -1.041  -0.848  -0.781  -0.862  -0.848  -0.792  -0.814
186   D        -1.479  -1.484  -1.409  -1.240  -1.262  -1.119  -1.098  -1.098  -0.994
187   E         0.043   0.049  -0.125   0.050   0.055  -0.192   0.029   0.038  -0.201
188   A        -1.479  -1.486  -1.413  -1.501  -1.515  -1.396  -1.098  -1.099  -0.996
189   Y        -0.726  -0.734  -0.725  -0.790  -0.801  -0.753  -0.723  -0.732  -0.688
190   A        -0.726  -0.647  -0.715  -0.632  -0.520  -0.607  -0.723  -0.634  -0.679
191   R        -0.329  -0.346  -0.298  -0.576  -0.597  -0.527  -0.498  -0.503  -0.440
192   E        -1.190  -1.190  -1.125  -1.251  -1.272  -1.160  -0.988  -0.985  -0.891
193   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
194   L        -0.409  -0.369  -0.336  -0.647  -0.575  -0.535  -0.597  -0.544  -0.493
195   T        -0.409  -0.362  -0.345  -0.498  -0.431  -0.406  -0.597  -0.547  -0.503
196   A        -0.846  -0.834  -0.773  -0.864  -0.853  -0.732  -0.848  -0.835  -0.739
197   A        -1.479  -1.481  -1.412  -1.204  -1.204  -1.125  -1.098  -1.095  -0.996
198   I         0.027   0.037   0.136  -0.300  -0.286  -0.142  -0.347  -0.334  -0.207
199   G         1.317   1.331   1.207   1.351   1.371   1.218   1.406   1.428   1.173
200   R        -0.846  -0.807  -0.773  -1.090  -1.033  -0.983  -0.848  -0.811  -0.739
201   H         1.317   1.249   1.194   1.461   1.380   1.331   1.406   1.286   1.148
202   C         2.006   2.027   2.155   2.282   2.314   2.517   2.282   2.317   2.546
203   R         0.043   0.022  -0.137   0.265   0.235   0.011   0.029   0.001  -0.217
204   V        -0.212  -0.119  -0.231  -0.255  -0.120  -0.282  -0.347  -0.224  -0.359
205   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
206   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
207   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
208   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
209   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
210   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
211   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
212   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
213   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
214   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
215   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
216   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
217   S        -1.163  -1.154  -1.111  -1.200  -1.194  -1.137  -0.973  -0.961  -0.882
218   A        -1.043  -1.060  -1.057  -0.946  -0.977  -0.977  -0.848  -0.864  -0.829
219   P         0.043  -0.004  -0.154   0.050  -0.018  -0.237   0.029  -0.036  -0.241
220   R         1.317   1.339   1.209   1.423   1.452   1.283   1.406   1.441   1.177
221   E         0.661   0.594   0.453   0.819   0.719   0.519   0.655   0.550   0.310
222   A         1.317   1.249   1.194   1.355   1.267   1.206   1.406   1.286   1.148
223   I        -0.846  -0.813  -0.775  -0.727  -0.681  -0.609  -0.848  -0.817  -0.740
224   L         0.027   0.050   0.135  -0.282  -0.250  -0.132  -0.347  -0.315  -0.208
225   R         0.978   1.036   1.002   0.917   1.009   0.918   0.780   0.887   0.752
226   Y         1.317   1.415   1.218   1.562   1.683   1.455   1.406   1.566   1.194
227   V         0.796   0.834   0.909   0.533   0.591   0.691   0.404   0.472   0.549
228   G         2.006   2.027   2.155   1.958   1.985   2.186   2.282   2.317   2.546
229   P        -0.409  -0.418  -0.360  -0.639  -0.650  -0.576  -0.597  -0.609  -0.521
230   L         0.224   0.202   0.255   0.021   0.000   0.074  -0.097  -0.106  -0.041
231   P        -0.726  -0.706  -0.697  -0.574  -0.546  -0.541  -0.723  -0.687  -0.656
232   -        -0.104  -0.046  -0.199  -0.178  -0.098  -0.341  -0.171  -0.096  -0.301
233   L         0.738   0.754   0.871   0.408   0.437   0.603   0.279   0.300   0.465
234   D        -0.726  -0.729  -0.722  -0.744  -0.738  -0.721  -0.723  -0.723  -0.687
235   V        -0.691  -0.692  -0.709  -0.693  -0.698  -0.774  -0.661  -0.663  -0.663
236   M        -0.828  -0.866  -0.781  -0.866  -0.889  -0.775  -0.825  -0.855  -0.743
237   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
238   G        -0.290  -0.278  -0.275  -0.377  -0.363  -0.345  -0.472  -0.452  -0.424
239   T        -1.163  -1.147  -1.100  -1.167  -1.140  -1.063  -0.973  -0.956  -0.873
240   W         2.006   2.027   2.155   2.261   2.294   2.496   2.282   2.317   2.546
241   C         0.027   0.050   0.135  -0.060  -0.003   0.103  -0.347  -0.315  -0.208
242   G         2.006   2.027   2.155   1.958   1.985   2.186   2.282   2.317   2.546
243   V         0.796   0.849   0.926   0.533   0.621   0.724   0.404   0.505   0.587
244   E         1.317   1.344   1.207   1.269   1.302   1.158   1.406   1.450   1.173
245   F         0.978   1.002   0.992   1.005   1.045   0.978   0.780   0.818   0.730
246   P         1.317   1.249   1.194   1.302   1.223   1.150   1.406   1.286   1.148
247   E         1.317   1.295   1.206   1.228   1.198   1.081   1.406   1.365   1.170
248   A         0.978   0.926   0.968   0.987   0.895   0.938   0.780   0.666   0.678
249   A        -0.529  -0.612  -0.661  -0.490  -0.632  -0.737  -0.472  -0.568  -0.609
250   G         2.006   2.027   2.155   1.958   1.985   2.186   2.282   2.317   2.546
251   K         2.006   2.027   2.155   1.977   2.010   2.206   2.282   2.317   2.546
252   N         2.006   2.027   2.155   2.070   2.107   2.300   2.282   2.317   2.546
253   D         0.738   0.756   0.874   0.414   0.441   0.608   0.279   0.304   0.471
254   G         2.006   2.027   2.155   1.958   1.985   2.186   2.282   2.317   2.546
255   R        -0.726  -0.751  -0.723  -0.756  -0.790  -0.752  -0.723  -0.747  -0.687
256   I         0.105   0.099   0.170  -0.017  -0.024   0.063  -0.222  -0.234  -0.151
257   N        -1.479  -1.449  -1.403  -1.462  -1.392  -1.356  -1.098  -1.071  -0.988
258   G         1.317   1.295   1.206   1.320   1.287   1.157   1.406   1.365   1.170
259   V        -0.409  -0.424  -0.345  -0.465  -0.483  -0.360  -0.597  -0.609  -0.504
260   T         0.027   0.020   0.129  -0.189  -0.197  -0.037  -0.347  -0.358  -0.217
261   L         0.360   0.373   0.337   0.457   0.500   0.414   0.154   0.196   0.111
262   F         1.317   1.344   1.207   1.568   1.609   1.458   1.406   1.450   1.173
263   G        -0.212  -0.144  -0.224  -0.318  -0.190  -0.319  -0.347  -0.242  -0.343
264   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
265   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
266   V        -0.290  -0.268  -0.289  -0.212  -0.207  -0.205  -0.472  -0.441  -0.441
267   A        -0.529  -0.555  -0.635  -0.382  -0.424  -0.545  -0.472  -0.504  -0.580
268   P        -1.479  -1.465  -1.407  -1.402  -1.369  -1.312  -1.098  -1.081  -0.992
269   G         0.224   0.180   0.238   0.079   0.023   0.099  -0.097  -0.148  -0.069
270   H         0.661   0.667   0.475   1.063   1.079   0.827   0.655   0.665   0.346
271   G         2.006   2.027   2.155   1.958   1.985   2.186   2.282   2.317   2.546
272   S         0.360   0.357   0.316   0.231   0.216   0.145   0.154   0.139   0.070
273   F         2.006   2.027   2.155   2.148   2.182   2.380   2.282   2.317   2.546
274   V         1.317   1.331   1.207   1.334   1.348   1.184   1.406   1.428   1.173
275   R         0.978   1.033   0.998   0.917   1.004   0.911   0.780   0.880   0.744
276   P         1.317   1.331   1.207   1.451   1.477   1.304   1.406   1.428   1.173
277   R        -1.163  -1.133  -1.096  -1.098  -1.055  -1.003  -0.973  -0.944  -0.870
278   A        -1.163  -1.125  -1.095  -1.109  -1.060  -1.019  -0.973  -0.938  -0.869
279   V         2.006   2.027   2.155   1.960   1.982   2.189   2.282   2.317   2.546
280   E         2.006   2.027   2.155   1.849   1.874   2.074   2.282   2.317   2.546
281   I         0.661   0.561   0.443   0.756   0.617   0.456   0.655   0.500   0.293
282   L         1.317   1.249   1.194   1.332   1.240   1.161   1.406   1.286   1.148
283   S         1.182   1.084   1.096   1.118   0.977   0.965   1.169   0.980   0.949
284   K         1.182   1.084   1.096   1.351   1.207   1.205   1.169   0.980   0.949
285   D         0.661   0.561   0.443   0.849   0.715   0.530   0.655   0.500   0.293
286   E        -0.212  -0.215  -0.251  -0.321  -0.332  -0.362  -0.347  -0.356  -0.383
287   E        -0.828  -0.828  -0.765  -0.963  -0.964  -0.853  -0.825  -0.818  -0.728
288   S        -0.104  -0.172  -0.233  -0.095  -0.195  -0.293  -0.171  -0.263  -0.347
289   A        -0.104  -0.168  -0.231   0.061  -0.035  -0.158  -0.171  -0.257  -0.345
290   E         0.170   0.142   0.218  -0.018  -0.064   0.044  -0.171  -0.200  -0.096
291   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
292   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
293   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
294   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
295   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
296   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
297   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
298   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
299   H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
300   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
301   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
302   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
303   E        -0.329  -0.306  -0.295  -0.657  -0.602  -0.609  -0.498  -0.455  -0.435
304   S        -0.104  -0.160  -0.209  -0.094  -0.174  -0.250  -0.171  -0.247  -0.315
305   D         0.550   0.524   0.403   0.553   0.523   0.349   0.483   0.441   0.228
306   D         0.796   0.835   0.907   0.384   0.458   0.526   0.404   0.475   0.544
307   E         1.317   1.331   1.207   1.226   1.242   1.078   1.406   1.428   1.173
308   I         0.796   0.828   0.906   0.546   0.611   0.691   0.404   0.461   0.543
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P53904
Output conservation file - output/P53904
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
