1     M         1.951   1.969   2.050   2.170   2.198   2.321   2.177   2.201   2.334
2     S         0.257   0.334   0.144   0.219   0.332   0.070   0.191   0.304   0.018
3     A        -0.651  -0.663  -0.644  -0.684  -0.714  -0.691  -0.683  -0.694  -0.658
4     A        -0.651  -0.637  -0.612  -0.747  -0.738  -0.703  -0.683  -0.664  -0.621
5     -        -0.080  -0.051  -0.037  -0.111  -0.067  -0.053  -0.306  -0.263  -0.251
6     -        -0.756  -0.745  -0.679  -0.872  -0.868  -0.756  -0.802  -0.784  -0.696
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -        -0.080  -0.097  -0.064  -0.259  -0.288  -0.256  -0.306  -0.331  -0.289
10    -        -0.080  -0.097  -0.064  -0.301  -0.341  -0.296  -0.306  -0.331  -0.289
11    -        -0.080  -0.097  -0.064   0.032   0.006   0.051  -0.306  -0.331  -0.289
12    -        -0.080  -0.051  -0.037  -0.159  -0.112  -0.106  -0.306  -0.263  -0.251
13    -        -0.080  -0.083  -0.044  -0.289  -0.300  -0.264  -0.306  -0.310  -0.261
14    -        -0.080  -0.035  -0.040  -0.035   0.052  -0.001  -0.306  -0.240  -0.255
15    -        -0.080  -0.070  -0.039  -0.299  -0.283  -0.244  -0.306  -0.291  -0.253
16    -        -0.756  -0.745  -0.679  -0.904  -0.882  -0.789  -0.802  -0.784  -0.696
17    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
19    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
20    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
21    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
22    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
23    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
24    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
25    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
26    I        -1.192  -1.177  -1.118  -1.241  -1.208  -1.129  -1.001  -0.980  -0.898
27    E        -0.651  -0.663  -0.644  -0.554  -0.589  -0.545  -0.683  -0.694  -0.658
28    K        -0.476  -0.531  -0.579  -0.555  -0.640  -0.686  -0.471  -0.537  -0.582
29    E         0.257   0.154   0.089   0.432   0.278   0.177   0.191   0.038  -0.064
30    T        -0.024   0.008  -0.019   0.016   0.063   0.032  -0.251  -0.207  -0.233
31    G         1.071   0.981   0.938   1.193   1.066   1.000   1.073   0.913   0.809
32    M        -0.476  -0.531  -0.579  -0.177  -0.274  -0.375  -0.471  -0.537  -0.582
33    L        -0.476  -0.531  -0.579  -0.436  -0.524  -0.582  -0.471  -0.537  -0.582
34    D         0.257   0.154   0.089   0.326   0.169   0.046   0.191   0.038  -0.064
35    V         0.708   0.723   0.742   0.620   0.641   0.654   0.411   0.433   0.429
36    G         1.951   1.969   2.050   1.997   2.020   2.146   2.177   2.201   2.334
37    K         0.708   0.756   0.762   0.369   0.445   0.443   0.411   0.496   0.469
38    H         0.257   0.272   0.103   0.561   0.587   0.324   0.191   0.213  -0.043
39    C         1.951   1.969   2.050   2.101   2.124   2.252   2.177   2.201   2.334
40    A        -0.476  -0.440  -0.509  -0.251  -0.193  -0.312  -0.471  -0.423  -0.499
41    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
42    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
43    Y         0.257   0.267   0.132   0.529   0.541   0.320   0.191   0.205   0.001
44    C         1.951   1.969   2.050   2.101   2.124   2.252   2.177   2.201   2.334
45    R        -0.024  -0.050  -0.040  -0.045  -0.088  -0.070  -0.251  -0.286  -0.267
46    Q         1.951   1.969   2.050   2.067   2.091   2.217   2.177   2.201   2.334
47    L         0.257   0.267   0.132   0.273   0.288   0.095   0.191   0.205   0.001
48    D         1.951   1.969   2.050   1.945   1.973   2.094   2.177   2.201   2.334
49    F         1.951   1.969   2.050   2.054   2.083   2.204   2.177   2.201   2.334
50    L         1.951   1.969   2.050   1.831   1.858   1.979   2.177   2.201   2.334
51    P         1.951   1.969   2.050   2.067   2.091   2.217   2.177   2.201   2.334
52    F         1.951   1.969   2.050   2.054   2.083   2.204   2.177   2.201   2.334
53    H         0.257   0.210   0.108   0.529   0.450   0.285   0.191   0.118  -0.036
54    C         1.951   1.969   2.050   2.101   2.124   2.252   2.177   2.201   2.334
55    S        -0.646  -0.657  -0.629  -0.782  -0.773  -0.756  -0.692  -0.698  -0.646
56    F        -1.097  -1.110  -1.070  -0.932  -0.969  -0.904  -0.913  -0.920  -0.855
57    C         1.951   1.969   2.050   2.101   2.124   2.252   2.177   2.201   2.334
58    N        -0.476  -0.480  -0.537  -0.423  -0.408  -0.524  -0.471  -0.477  -0.532
59    E        -0.646  -0.629  -0.616  -0.722  -0.710  -0.666  -0.692  -0.668  -0.632
60    D         0.597   0.616   0.690   0.399   0.434   0.541   0.191   0.219   0.323
61    F         1.071   1.054   0.947   1.289   1.273   1.134   1.073   1.040   0.827
62    C         1.951   1.969   2.050   2.101   2.124   2.252   2.177   2.201   2.334
63    S         0.257   0.205   0.110   0.146   0.063  -0.086   0.191   0.111  -0.032
64    N        -1.097  -1.108  -1.080  -1.042  -1.065  -1.017  -0.913  -0.917  -0.864
65    H         1.951   1.969   2.050   2.129   2.155   2.280   2.177   2.201   2.334
66    R         1.951   1.969   2.050   2.000   2.023   2.150   2.177   2.201   2.334
67    L        -0.646  -0.631  -0.617  -0.865  -0.839  -0.812  -0.692  -0.670  -0.633
68    K        -0.476  -0.531  -0.579  -0.595  -0.675  -0.740  -0.471  -0.537  -0.582
69    E         1.071   0.981   0.938   1.159   1.022   0.941   1.073   0.913   0.809
70    D        -0.024   0.033   0.005  -0.222  -0.136  -0.161  -0.251  -0.168  -0.199
71    H         1.951   1.969   2.050   2.129   2.155   2.280   2.177   2.201   2.334
72    H        -0.024  -0.080  -0.043   0.109   0.024   0.071  -0.251  -0.318  -0.267
73    C         1.951   1.969   2.050   2.101   2.124   2.252   2.177   2.201   2.334
74    R        -1.548  -1.531  -1.477  -1.355  -1.334  -1.245  -1.133  -1.111  -1.033
75    W        -0.646  -0.663  -0.634  -0.485  -0.518  -0.473  -0.692  -0.703  -0.650
76    L        -0.024  -0.080  -0.043  -0.342  -0.431  -0.381  -0.251  -0.318  -0.267
77    L        -0.651  -0.682  -0.644  -0.833  -0.868  -0.838  -0.683  -0.716  -0.658
78    E        -1.192  -1.173  -1.118  -1.185  -1.177  -1.072  -1.001  -0.976  -0.898
79    H        -0.651  -0.682  -0.644  -0.328  -0.365  -0.314  -0.683  -0.716  -0.658
80    E        -1.192  -1.173  -1.118  -1.100  -1.082  -0.987  -1.001  -0.976  -0.898
81    E        -0.024  -0.017  -0.020  -0.045  -0.020  -0.031  -0.251  -0.232  -0.237
82    V        -1.097  -1.081  -1.080  -0.898  -0.872  -0.886  -0.913  -0.891  -0.864
83    H        -0.646  -0.627  -0.612  -0.503  -0.478  -0.454  -0.692  -0.665  -0.628
84    K        -0.476  -0.485  -0.543  -0.617  -0.626  -0.719  -0.471  -0.482  -0.540
85    -        -0.651  -0.667  -0.624  -0.834  -0.857  -0.795  -0.683  -0.698  -0.636
86    -        -0.651  -0.660  -0.635  -0.607  -0.635  -0.600  -0.683  -0.689  -0.648
87    T        -1.097  -1.108  -1.080  -0.950  -0.963  -0.931  -0.913  -0.917  -0.864
88    E        -1.548  -1.531  -1.477  -1.513  -1.500  -1.404  -1.133  -1.111  -1.033
89    K        -1.097  -1.106  -1.070  -1.165  -1.173  -1.116  -0.913  -0.916  -0.854
90    S        -1.097  -1.114  -1.088  -0.986  -0.994  -0.933  -0.913  -0.923  -0.871
91    P         0.257   0.272   0.103   0.532   0.558   0.313   0.191   0.213  -0.043
92    S        -1.097  -1.053  -1.053  -1.061  -1.008  -0.983  -0.913  -0.862  -0.838
93    K        -0.024   0.039  -0.005  -0.289  -0.187  -0.282  -0.251  -0.159  -0.217
94    S        -0.080  -0.112  -0.073  -0.347  -0.402  -0.338  -0.306  -0.354  -0.304
95    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
96    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
97    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
98    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
99    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
100   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
101   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
102   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
103   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
104   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
105   R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
106   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
107   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
108   S        -0.080  -0.112  -0.073  -0.371  -0.399  -0.367  -0.306  -0.354  -0.304
109   S        -0.080  -0.097  -0.063  -0.479  -0.517  -0.476  -0.306  -0.334  -0.288
110   S         0.637   0.688   0.729   0.328   0.437   0.467   0.270   0.363   0.402
111   N         0.974   0.889   0.870   0.971   0.851   0.806   0.906   0.748   0.681
112   D         0.095   0.069   0.032   0.178   0.120   0.065  -0.048  -0.091  -0.149
113   E         0.095   0.069   0.032   0.239   0.197   0.146  -0.048  -0.091  -0.149
114   A        -0.651  -0.612  -0.613  -0.918  -0.864  -0.863  -0.683  -0.633  -0.623
115   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
116   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
117   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
118   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
119   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
120   Y        -1.097  -1.110  -1.079  -0.848  -0.861  -0.825  -0.913  -0.919  -0.863
121   F        -0.476  -0.531  -0.579  -0.303  -0.392  -0.498  -0.471  -0.537  -0.582
122   K        -0.646  -0.689  -0.623  -0.719  -0.777  -0.679  -0.692  -0.728  -0.639
123   S         1.951   1.969   2.050   1.755   1.786   1.901   2.177   2.201   2.334
124   L         1.951   1.969   2.050   1.831   1.858   1.979   2.177   2.201   2.334
125   L        -0.024  -0.080  -0.043  -0.123  -0.194  -0.133  -0.251  -0.318  -0.267
126   P         1.951   1.969   2.050   2.067   2.091   2.217   2.177   2.201   2.334
127   E        -0.646  -0.663  -0.634  -0.596  -0.626  -0.570  -0.692  -0.703  -0.650
128   R         0.257   0.218   0.109   0.367   0.308   0.114   0.191   0.128  -0.034
129   A        -0.476  -0.531  -0.579  -0.314  -0.401  -0.459  -0.471  -0.537  -0.582
130   S        -1.548  -1.531  -1.477  -1.354  -1.329  -1.243  -1.133  -1.111  -1.033
131   V        -0.476  -0.478  -0.543  -0.298  -0.297  -0.391  -0.471  -0.474  -0.539
132   R        -0.024  -0.080  -0.043  -0.242  -0.343  -0.313  -0.251  -0.318  -0.267
133   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
134   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
135   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
136   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
137   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
138   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
139   I        -0.646  -0.593  -0.616  -0.665  -0.601  -0.612  -0.692  -0.631  -0.631
140   Q         1.071   1.126   0.965   0.920   0.994   0.787   1.073   1.161   0.860
141   R        -1.097  -1.081  -1.080  -1.025  -0.979  -0.985  -0.913  -0.891  -0.864
142   V        -1.097  -1.081  -1.080  -0.768  -0.754  -0.726  -0.913  -0.891  -0.864
143   S        -1.097  -1.114  -1.088  -1.109  -1.142  -1.073  -0.913  -0.923  -0.871
144   E        -1.548  -1.531  -1.477  -1.438  -1.432  -1.328  -1.133  -1.111  -1.033
145   T        -1.097  -1.048  -1.059  -1.015  -0.921  -0.967  -0.913  -0.857  -0.844
146   R        -0.646  -0.597  -0.616  -0.729  -0.647  -0.683  -0.692  -0.637  -0.632
147   E        -1.097  -1.078  -1.061  -0.976  -0.923  -0.915  -0.913  -0.889  -0.846
148   P        -1.548  -1.531  -1.477  -1.360  -1.340  -1.250  -1.133  -1.111  -1.033
149   L        -1.548  -1.531  -1.477  -1.569  -1.490  -1.461  -1.133  -1.111  -1.033
150   R        -0.476  -0.478  -0.543  -0.265  -0.296  -0.388  -0.471  -0.474  -0.539
151   G        -1.097  -1.055  -1.060  -1.139  -1.085  -1.075  -0.913  -0.864  -0.845
152   S        -1.548  -1.531  -1.477  -1.488  -1.500  -1.379  -1.133  -1.111  -1.033
153   N        -1.097  -1.055  -1.060  -0.908  -0.841  -0.849  -0.913  -0.864  -0.845
154   T        -0.646  -0.657  -0.613  -0.692  -0.686  -0.644  -0.692  -0.697  -0.629
155   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
156   -         0.637   0.644   0.701   0.379   0.390   0.469   0.270   0.277   0.345
157   -         0.637   0.670   0.718   0.340   0.408   0.453   0.270   0.328   0.381
158   -        -0.651  -0.649  -0.634  -0.745  -0.753  -0.707  -0.683  -0.678  -0.647
159   -        -1.192  -1.180  -1.118  -1.317  -1.284  -1.206  -1.001  -0.982  -0.898
160   -        -0.756  -0.744  -0.679  -0.790  -0.777  -0.673  -0.802  -0.783  -0.696
161   -        -0.080  -0.076  -0.052  -0.073  -0.076  -0.048  -0.306  -0.301  -0.272
162   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
163   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
164   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
165   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
166   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
167   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
168   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
169   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
170   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
171   A        -0.080  -0.038  -0.032  -0.104  -0.058  -0.037  -0.306  -0.245  -0.243
172   K        -0.080  -0.115  -0.073  -0.359  -0.414  -0.342  -0.306  -0.357  -0.304
173   V        -0.080  -0.077  -0.052  -0.096  -0.109  -0.066  -0.306  -0.304  -0.273
174   S        -0.080  -0.077  -0.052  -0.207  -0.189  -0.149  -0.306  -0.304  -0.273
175   S        -0.080  -0.115  -0.073  -0.273  -0.315  -0.250  -0.306  -0.357  -0.304
176   T        -0.646  -0.689  -0.627  -0.733  -0.793  -0.699  -0.692  -0.728  -0.643
177   L        -0.646  -0.630  -0.620  -0.849  -0.833  -0.796  -0.692  -0.669  -0.635
178   N        -0.646  -0.689  -0.627  -0.778  -0.827  -0.732  -0.692  -0.728  -0.643
179   S        -1.097  -1.110  -1.070  -1.135  -1.174  -1.083  -0.913  -0.920  -0.855
180   K        -1.548  -1.531  -1.477  -1.589  -1.571  -1.481  -1.133  -1.111  -1.033
181   T         0.257   0.276   0.134   0.368   0.375   0.190   0.191   0.218   0.004
182   L         0.257   0.326   0.143   0.294   0.393   0.141   0.191   0.293   0.018
183   D        -1.097  -1.108  -1.080  -1.079  -1.092  -1.069  -0.913  -0.917  -0.864
184   K         1.071   0.981   0.938   0.906   0.787   0.725   1.073   0.913   0.809
185   I        -0.024   0.037  -0.014  -0.055   0.055  -0.035  -0.251  -0.162  -0.227
186   F        -1.548  -1.531  -1.477  -1.495  -1.502  -1.386  -1.133  -1.111  -1.033
187   K        -0.476  -0.485  -0.543  -0.584  -0.605  -0.675  -0.471  -0.482  -0.540
188   F         1.071   0.981   0.938   1.302   1.193   1.141   1.073   0.913   0.809
189   F        -0.024  -0.080  -0.043  -0.053  -0.132  -0.089  -0.251  -0.318  -0.267
190   Q        -1.097  -1.055  -1.060  -1.088  -1.043  -1.013  -0.913  -0.864  -0.845
191   R        -1.097  -1.114  -1.088  -1.077  -1.099  -1.095  -0.913  -0.923  -0.871
192   N        -0.646  -0.657  -0.629  -0.665  -0.693  -0.650  -0.692  -0.698  -0.646
193   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
194   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
195   R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
196   K         0.257   0.205   0.110   0.165   0.093  -0.029   0.191   0.111  -0.032
197   S        -0.646  -0.630  -0.620  -0.847  -0.798  -0.805  -0.692  -0.669  -0.635
198   N        -1.097  -1.110  -1.070  -1.206  -1.235  -1.186  -0.913  -0.920  -0.855
199   N        -0.476  -0.478  -0.543  -0.573  -0.587  -0.660  -0.471  -0.474  -0.539
200   K         1.071   0.981   0.938   0.906   0.787   0.725   1.073   0.913   0.809
201   S         1.071   1.131   0.960   0.961   1.048   0.812   1.073   1.169   0.851
202   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
203   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
204   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
205   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
206   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
207   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
208   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
209   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
210   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
211   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
212   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
213   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
214   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
215   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
216   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
217   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
218   K         1.071   1.116   0.966   0.904   0.967   0.764   1.073   1.144   0.862
219   K        -0.476  -0.490  -0.540  -0.598  -0.605  -0.689  -0.471  -0.489  -0.536
220   N        -0.024   0.015  -0.015  -0.440  -0.376  -0.425  -0.251  -0.198  -0.228
221   F        -0.646  -0.661  -0.616  -0.594  -0.604  -0.554  -0.692  -0.701  -0.631
222   G        -0.651  -0.614  -0.613  -0.679  -0.623  -0.611  -0.683  -0.636  -0.623
223   S        -0.024  -0.049  -0.028  -0.196  -0.218  -0.175  -0.251  -0.284  -0.250
224   S         0.708   0.668   0.715   0.392   0.313   0.382   0.411   0.324   0.375
225   S        -0.646  -0.630  -0.620  -0.789  -0.762  -0.728  -0.692  -0.669  -0.635
226   N         0.257   0.154   0.089   0.300   0.160   0.035   0.191   0.038  -0.064
227   K         0.708   0.694   0.725   0.373   0.348   0.391   0.411   0.375   0.394
228   I        -0.646  -0.595  -0.615  -0.653  -0.574  -0.584  -0.692  -0.633  -0.631
229   I         0.257   0.280   0.129   0.413   0.443   0.218   0.191   0.224  -0.004
230   Q        -0.646  -0.661  -0.616  -0.532  -0.568  -0.485  -0.692  -0.701  -0.631
231   L        -0.646  -0.630  -0.620  -0.612  -0.575  -0.538  -0.692  -0.669  -0.635
232   A        -0.476  -0.485  -0.543  -0.433  -0.465  -0.559  -0.471  -0.482  -0.540
233   N        -0.646  -0.634  -0.612  -0.719  -0.680  -0.672  -0.692  -0.673  -0.628
234   L         1.071   1.116   0.966   1.075   1.135   0.954   1.073   1.144   0.862
235   K         1.071   1.054   0.947   0.906   0.886   0.739   1.073   1.040   0.827
236   K         0.708   0.720   0.736   0.373   0.391   0.407   0.411   0.427   0.416
237   I        -0.476  -0.435  -0.535  -0.301  -0.234  -0.397  -0.471  -0.418  -0.530
238   A         1.951   1.969   2.050   1.929   1.935   2.078   2.177   2.201   2.334
239   K         1.951   1.969   2.050   1.697   1.724   1.843   2.177   2.201   2.334
240   G         1.951   1.969   2.050   1.997   2.020   2.146   2.177   2.201   2.334
241   D         1.951   1.969   2.050   1.945   1.973   2.094   2.177   2.201   2.334
242   P        -1.097  -1.048  -1.059  -1.003  -0.911  -0.948  -0.913  -0.857  -0.844
243   K         1.071   1.116   0.966   0.855   0.921   0.687   1.073   1.144   0.862
244   I         1.071   1.054   0.947   1.192   1.174   1.017   1.073   1.040   0.827
245   P         0.257   0.272   0.103   0.507   0.529   0.276   0.191   0.213  -0.043
246   M        -0.646  -0.689  -0.623  -0.436  -0.491  -0.390  -0.692  -0.728  -0.639
247   Q        -1.097  -1.114  -1.088  -0.866  -0.898  -0.864  -0.913  -0.923  -0.871
248   N        -0.024  -0.080  -0.043  -0.210  -0.299  -0.263  -0.251  -0.318  -0.267
249   R         1.071   1.054   0.947   1.148   1.121   0.940   1.073   1.040   0.827
250   I         1.951   1.969   2.050   1.990   2.020   2.140   2.177   2.201   2.334
251   Y         1.951   1.969   2.050   2.145   2.172   2.296   2.177   2.201   2.334
252   I        -0.024  -0.021  -0.028  -0.126  -0.148  -0.148  -0.251  -0.256  -0.251
253   W         0.708   0.694   0.725   0.903   0.875   0.911   0.411   0.375   0.394
254   C         1.071   0.981   0.938   1.301   1.172   1.109   1.073   0.913   0.809
255   Y        -0.651  -0.660  -0.636  -0.465  -0.492  -0.462  -0.683  -0.689  -0.648
256   L        -0.109  -0.078  -0.072  -0.104  -0.052  -0.060  -0.365  -0.325  -0.307
257   V         0.637   0.637   0.694   0.489   0.480   0.559   0.270   0.262   0.331
258   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
259   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
260   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
261   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
262   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
263   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
264   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
265   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
266   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
267   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
268   D        -0.476  -0.385  -0.533  -0.348  -0.207  -0.456  -0.471  -0.354  -0.527
269   G        -1.548  -1.531  -1.477  -1.440  -1.418  -1.330  -1.133  -1.111  -1.033
270   D        -0.476  -0.531  -0.579  -0.289  -0.371  -0.433  -0.471  -0.537  -0.582
271   E        -1.097  -1.114  -1.088  -1.060  -1.099  -1.075  -0.913  -0.923  -0.871
272   T        -1.097  -1.114  -1.088  -1.139  -1.161  -1.166  -0.913  -0.923  -0.871
273   D        -1.548  -1.531  -1.477  -1.340  -1.301  -1.229  -1.133  -1.111  -1.033
274   I         0.257   0.218   0.109   0.406   0.343   0.177   0.191   0.128  -0.034
275   A        -1.097  -1.108  -1.080  -1.148  -1.200  -1.145  -0.913  -0.917  -0.864
276   K        -1.192  -1.177  -1.118  -1.287  -1.263  -1.175  -1.001  -0.980  -0.898
277   E        -0.651  -0.650  -0.635  -0.702  -0.721  -0.697  -0.683  -0.678  -0.648
278   D        -1.192  -1.177  -1.118  -1.168  -1.117  -1.055  -1.001  -0.980  -0.898
279   T        -0.651  -0.663  -0.644  -0.524  -0.538  -0.516  -0.683  -0.694  -0.658
280   R         0.974   1.009   0.919   0.764   0.816   0.686   0.906   0.963   0.774
281   M        -1.097  -1.081  -1.080  -1.068  -1.043  -1.008  -0.913  -0.891  -0.864
282   P        -0.024  -0.051  -0.028   0.031  -0.026   0.018  -0.251  -0.288  -0.251
283   L        -0.024  -0.060  -0.018  -0.107  -0.140  -0.082  -0.251  -0.286  -0.231
284   Y        -0.024  -0.012  -0.003   0.175   0.206   0.233  -0.251  -0.222  -0.209
285   I         0.257   0.154   0.089   0.465   0.329   0.232   0.191   0.038  -0.064
286   N         0.708   0.723   0.742   0.440   0.472   0.456   0.411   0.433   0.429
287   K         1.951   1.969   2.050   1.697   1.724   1.843   2.177   2.201   2.334
288   M        -1.097  -1.108  -1.080  -0.736  -0.751  -0.721  -0.913  -0.917  -0.864
289   W         1.951   1.969   2.050   2.210   2.235   2.362   2.177   2.201   2.334
290   P        -0.024  -0.050  -0.040  -0.031  -0.084  -0.085  -0.251  -0.286  -0.267
291   V         1.071   1.116   0.966   1.177   1.235   1.034   1.073   1.144   0.862
292   G         1.951   1.969   2.050   1.997   2.020   2.146   2.177   2.201   2.334
293   R         1.951   1.969   2.050   2.000   2.023   2.150   2.177   2.201   2.334
294   A         0.257   0.210   0.108   0.311   0.224   0.065   0.191   0.118  -0.036
295   M         1.071   1.126   0.965   1.075   1.147   0.952   1.073   1.161   0.860
296   D         1.951   1.969   2.050   1.945   1.973   2.094   2.177   2.201   2.334
297   Y        -0.024  -0.060  -0.018  -0.145  -0.198  -0.126  -0.251  -0.286  -0.231
298   L        -0.024  -0.080  -0.043  -0.172  -0.252  -0.191  -0.251  -0.318  -0.267
299   S         0.708   0.760   0.770   0.474   0.553   0.550   0.411   0.505   0.485
300   I        -1.097  -1.081  -1.080  -0.960  -0.930  -0.933  -0.913  -0.891  -0.864
301   Q        -0.646  -0.663  -0.634  -0.570  -0.593  -0.543  -0.692  -0.703  -0.650
302   L         1.951   1.969   2.050   1.831   1.858   1.979   2.177   2.201   2.334
303   N        -0.024  -0.061  -0.018  -0.001  -0.038   0.030  -0.251  -0.288  -0.235
304   V         0.708   0.723   0.742   0.620   0.641   0.654   0.411   0.433   0.429
305   K        -0.646  -0.627  -0.616  -0.705  -0.659  -0.634  -0.692  -0.666  -0.632
306   S         1.071   1.126   0.965   1.053   1.140   0.882   1.073   1.161   0.860
307   S        -0.646  -0.593  -0.616  -0.825  -0.719  -0.775  -0.692  -0.631  -0.631
308   T         1.071   1.126   0.965   1.100   1.182   0.955   1.073   1.161   0.860
309   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
310   L         0.257   0.330   0.149   0.288   0.403   0.117   0.191   0.298   0.026
311   T        -1.097  -1.112  -1.064  -0.797  -0.818  -0.734  -0.913  -0.921  -0.849
312   N        -0.646  -0.597  -0.616  -0.765  -0.694  -0.722  -0.692  -0.637  -0.632
313   S        -1.097  -1.053  -1.053  -1.090  -1.017  -1.013  -0.913  -0.862  -0.838
314   S        -0.646  -0.657  -0.629  -0.811  -0.838  -0.791  -0.692  -0.698  -0.646
315   S        -0.476  -0.485  -0.543  -0.584  -0.585  -0.695  -0.471  -0.482  -0.540
316   N        -1.097  -1.078  -1.061  -1.028  -0.986  -0.978  -0.913  -0.889  -0.846
317   D         0.708   0.692   0.723   0.626   0.588   0.617   0.411   0.372   0.389
318   K         0.708   0.668   0.715   0.373   0.308   0.378   0.411   0.324   0.375
319   F         1.071   1.126   0.965   1.051   1.125   0.915   1.073   1.161   0.860
320   Q        -1.097  -1.110  -1.079  -0.782  -0.798  -0.750  -0.913  -0.919  -0.863
321   L        -0.024  -0.080  -0.043  -0.159  -0.231  -0.174  -0.251  -0.318  -0.267
322   C        -0.195  -0.180  -0.111  -0.080  -0.062   0.046  -0.471  -0.450  -0.357
323   K         1.071   0.981   0.938   0.934   0.822   0.771   1.073   0.913   0.809
324   L        -0.646  -0.596  -0.611  -0.618  -0.547  -0.543  -0.692  -0.634  -0.627
325   K        -0.646  -0.629  -0.616  -0.710  -0.674  -0.675  -0.692  -0.668  -0.632
326   E        -0.109  -0.136  -0.076  -0.186  -0.221  -0.130  -0.365  -0.393  -0.312
327   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
328   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
329   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
330   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
331   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
332   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
333   K        -0.080  -0.115  -0.073  -0.331  -0.381  -0.309  -0.306  -0.357  -0.304
334   Q        -0.651  -0.609  -0.635  -0.627  -0.566  -0.605  -0.683  -0.629  -0.648
335   V        -1.192  -1.181  -1.118  -1.216  -1.197  -1.103  -1.001  -0.983  -0.898
336   S        -0.651  -0.649  -0.618  -0.690  -0.688  -0.661  -0.683  -0.677  -0.628
337   F        -0.651  -0.609  -0.635  -0.364  -0.300  -0.333  -0.683  -0.629  -0.648
338   Y        -1.192  -1.181  -1.118  -1.011  -0.999  -0.896  -1.001  -0.983  -0.898
339   N        -0.646  -0.592  -0.611  -0.567  -0.461  -0.504  -0.692  -0.630  -0.627
340   I        -0.024  -0.051  -0.028  -0.114  -0.165  -0.132  -0.251  -0.288  -0.251
341   G        -0.476  -0.391  -0.505  -0.311  -0.183  -0.362  -0.471  -0.362  -0.494
342   A        -0.476  -0.488  -0.534  -0.344  -0.358  -0.450  -0.471  -0.486  -0.529
343   S         0.257   0.154   0.089   0.162   0.011  -0.097   0.191   0.038  -0.064
344   L        -1.097  -1.110  -1.070  -1.029  -1.051  -0.978  -0.913  -0.920  -0.855
345   R         0.708   0.691   0.724   0.515   0.465   0.477   0.411   0.370   0.391
346   V         0.095  -0.002  -0.003   0.199   0.054   0.058  -0.048  -0.192  -0.201
347   T        -0.646  -0.659  -0.629  -0.780  -0.785  -0.733  -0.692  -0.700  -0.645
348   N        -1.097  -1.017  -1.058  -1.176  -1.070  -1.106  -0.913  -0.825  -0.843
349   E        -1.548  -1.531  -1.477  -1.341  -1.326  -1.231  -1.133  -1.111  -1.033
350   I        -0.646  -0.593  -0.616  -0.646  -0.582  -0.590  -0.692  -0.631  -0.631
351   K         0.257   0.205   0.110   0.161   0.086  -0.035   0.191   0.111  -0.032
352   D        -0.646  -0.599  -0.619  -0.647  -0.578  -0.593  -0.692  -0.637  -0.634
353   L        -0.024  -0.012  -0.003  -0.121  -0.092  -0.080  -0.251  -0.222  -0.209
354   D         1.071   0.981   0.938   1.132   1.008   0.932   1.073   0.913   0.809
355   T         1.071   1.054   0.947   1.192   1.172   1.017   1.073   1.040   0.827
356   L         0.597   0.616   0.690   0.317   0.358   0.463   0.191   0.219   0.323
357   Y         1.071   0.981   0.938   1.344   1.219   1.151   1.073   0.913   0.809
358   L         1.951   1.969   2.050   1.831   1.858   1.979   2.177   2.201   2.334
359   V         1.071   0.981   0.938   1.145   1.011   0.937   1.073   0.913   0.809
360   H         1.071   1.126   0.965   1.233   1.302   1.103   1.073   1.161   0.860
361   N         1.071   1.126   0.965   1.183   1.258   1.027   1.073   1.161   0.860
362   N        -1.548  -1.531  -1.477  -1.445  -1.415  -1.335  -1.133  -1.111  -1.033
363   A        -0.024  -0.004  -0.017  -0.034  -0.017  -0.023  -0.251  -0.232  -0.234
364   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
365   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
366   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
367   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
368   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
369   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
370   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
371   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P53899
Output conservation file - output/P53899
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
