1     M         1.920   1.965   2.080   2.179   2.256   2.437   2.162   2.232   2.438
2     M        -1.530  -1.446  -1.439  -1.123  -1.064  -0.984  -1.175  -1.088  -1.038
3     S        -1.161  -1.111  -1.069  -1.246  -1.139  -1.139  -1.017  -0.955  -0.884
4     D        -1.161  -1.174  -1.111  -1.185  -1.162  -1.077  -1.017  -1.019  -0.924
5     Q        -1.617  -1.568  -1.494  -1.616  -1.521  -1.444  -1.244  -1.188  -1.083
6     E         1.031   1.110   0.942   0.789   0.897   0.657   1.026   1.156   0.822
7     N        -1.617  -1.568  -1.494  -1.238  -1.149  -1.058  -1.244  -1.188  -1.083
8     E        -0.132  -0.048  -0.056  -0.146   0.010  -0.054  -0.393  -0.267  -0.297
9     N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    A        -1.139  -1.132  -1.071  -0.966  -0.961  -0.881  -1.008  -0.984  -0.890
17    K        -1.139  -1.118  -1.080  -1.003  -0.925  -0.874  -1.008  -0.971  -0.897
18    A        -0.357  -0.379  -0.509   0.005  -0.020  -0.181  -0.341  -0.366  -0.519
19    F         0.034  -0.011   0.014   0.069   0.026   0.046  -0.174  -0.219  -0.200
20    L        -1.139  -1.041  -1.079  -1.333  -1.242  -1.252  -1.008  -0.896  -0.897
21    G        -0.992  -1.045  -1.032  -0.856  -0.965  -1.010  -0.841  -0.892  -0.847
22    L         1.920   1.965   2.080   1.872   1.937   2.123   2.162   2.232   2.438
23    A         0.348   0.293   0.149   0.628   0.560   0.374   0.327   0.241   0.017
24    K        -0.748  -0.756  -0.644  -1.238  -1.205  -1.067  -0.841  -0.829  -0.689
25    C        -0.601  -0.540  -0.591  -0.242  -0.214  -0.222  -0.674  -0.615  -0.631
26    E         1.920   1.965   2.080   1.586   1.632   1.830   2.162   2.232   2.438
27    E        -1.139  -1.118  -1.080  -1.249  -1.140  -1.141  -1.008  -0.971  -0.897
28    E         1.110   1.234   1.009   0.833   0.982   0.676   1.161   1.358   0.950
29    V        -0.210  -0.179  -0.089  -0.099  -0.068   0.066  -0.507  -0.467  -0.347
30    D        -1.139  -1.186  -1.079  -1.220  -1.310  -1.148  -1.008  -1.032  -0.897
31    A        -0.992  -0.937  -1.000  -0.993  -0.931  -1.007  -0.841  -0.776  -0.813
32    I        -0.062   0.023   0.003  -0.061   0.051   0.049  -0.341  -0.239  -0.233
33    E         1.920   1.965   2.080   1.586   1.632   1.830   2.162   2.232   2.438
34    R        -1.139  -1.101  -1.067  -0.914  -0.840  -0.805  -1.008  -0.959  -0.887
35    E         0.739   0.838   0.798   0.247   0.391   0.292   0.494   0.667   0.535
36    V        -0.062   0.032  -0.001  -0.096   0.033   0.014  -0.341  -0.222  -0.235
37    E        -0.992  -1.073  -1.066  -1.098  -1.224  -1.177  -0.841  -0.919  -0.881
38    L        -1.530  -1.536  -1.471  -1.237  -1.253  -1.134  -1.175  -1.165  -1.065
39    Y         0.348   0.153   0.106   0.628   0.361   0.257   0.327   0.037  -0.048
40    R         0.034   0.023  -0.012   0.178   0.141   0.078  -0.174  -0.221  -0.244
41    L        -0.601  -0.683  -0.597  -0.526  -0.594  -0.487  -0.674  -0.744  -0.632
42    N        -0.992  -1.044  -1.032  -0.934  -1.031  -0.975  -0.841  -0.891  -0.846
43    K        -0.062   0.034  -0.002  -0.281  -0.135  -0.140  -0.341  -0.217  -0.236
44    M        -0.601  -0.706  -0.623  -0.268  -0.418  -0.313  -0.674  -0.772  -0.664
45    K        -0.357  -0.321  -0.488  -0.007   0.052  -0.219  -0.341  -0.297  -0.493
46    P         1.110   1.183   1.000   1.323   1.429   1.184   1.161   1.276   0.933
47    V        -0.748  -0.682  -0.649  -0.615  -0.538  -0.468  -0.841  -0.756  -0.695
48    Y         0.034   0.098   0.033   0.172   0.250   0.166  -0.174  -0.102  -0.179
49    E        -0.357  -0.232  -0.468  -0.590  -0.418  -0.793  -0.341  -0.171  -0.468
50    K         0.348   0.341   0.180   0.369   0.378   0.175   0.327   0.308   0.065
51    R         1.920   1.965   2.080   2.066   2.133   2.321   2.162   2.232   2.438
52    D        -0.062  -0.102  -0.028  -0.295  -0.340  -0.248  -0.341  -0.371  -0.268
53    A        -1.530  -1.456  -1.441  -1.421  -1.349  -1.282  -1.175  -1.097  -1.041
54    Y        -0.357  -0.321  -0.488  -0.125  -0.064  -0.310  -0.341  -0.297  -0.493
55    I        -0.062  -0.102  -0.028  -0.179  -0.207  -0.102  -0.341  -0.371  -0.268
56    D        -0.992  -0.939  -1.003  -1.093  -0.981  -1.141  -0.841  -0.778  -0.816
57    E        -1.139  -1.099  -1.061  -1.116  -1.014  -0.979  -1.008  -0.957  -0.881
58    I         1.920   1.965   2.080   1.919   2.000   2.171   2.162   2.232   2.438
59    A         0.348   0.344   0.179   0.669   0.669   0.451   0.327   0.312   0.064
60    E        -1.139  -1.041  -1.079  -1.154  -0.938  -1.023  -1.008  -0.896  -0.897
61    F         1.920   1.965   2.080   1.965   2.028   2.218   2.162   2.232   2.438
62    W         1.920   1.965   2.080   2.158   2.230   2.415   2.162   2.232   2.438
63    K        -1.139  -1.178  -1.098  -0.968  -0.969  -0.861  -1.008  -1.026  -0.914
64    I         0.348   0.153   0.106   0.515   0.256   0.161   0.327   0.037  -0.048
65    V         1.110   1.204   0.998   1.291   1.420   1.158   1.161   1.310   0.928
66    L         1.110   1.015   0.967   1.168   1.047   0.985   1.161   0.992   0.870
67    S        -0.748  -0.673  -0.652  -0.910  -0.871  -0.771  -0.841  -0.749  -0.696
68    Q         0.034  -0.007   0.018   0.034  -0.014  -0.015  -0.174  -0.214  -0.194
69    H        -0.210  -0.201  -0.106  -0.041  -0.048   0.090  -0.507  -0.496  -0.371
70    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
71    V        -0.992  -0.905  -1.022  -0.880  -0.760  -0.885  -0.841  -0.743  -0.836
72    S         0.034   0.036   0.056  -0.275  -0.276  -0.274  -0.174  -0.144  -0.133
73    F         0.739   0.658   0.740   0.703   0.546   0.653   0.494   0.314   0.414
74    A        -0.601  -0.644  -0.598  -0.541  -0.634  -0.556  -0.674  -0.717  -0.639
75    N        -0.601  -0.691  -0.602  -0.712  -0.855  -0.714  -0.674  -0.753  -0.640
76    Y         1.110   1.234   1.009   1.342   1.515   1.224   1.161   1.358   0.950
77    I         0.739   0.821   0.793   0.687   0.830   0.750   0.494   0.636   0.524
78    R        -0.601  -0.706  -0.623  -0.368  -0.491  -0.376  -0.674  -0.772  -0.664
79    A        -0.062   0.007  -0.006  -0.000   0.111   0.121  -0.341  -0.240  -0.238
80    S        -0.601  -0.706  -0.623  -0.748  -0.915  -0.816  -0.674  -0.772  -0.664
81    D         1.920   1.965   2.080   1.694   1.760   1.940   2.162   2.232   2.438
82    F        -0.210  -0.201  -0.106  -0.350  -0.350  -0.217  -0.507  -0.496  -0.371
83    K         0.348   0.153   0.106   0.334   0.093   0.011   0.327   0.037  -0.048
84    Y         0.739   0.658   0.740   0.763   0.601   0.699   0.494   0.314   0.414
85    I         0.572   0.586   0.698   0.324   0.336   0.494   0.160   0.166   0.326
86    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
87    D         0.034   0.032   0.044  -0.407  -0.391  -0.390  -0.174  -0.150  -0.151
88    T        -1.530  -1.508  -1.469  -1.237  -1.233  -1.172  -1.175  -1.144  -1.063
89    I         0.739   0.658   0.740   0.641   0.490   0.585   0.494   0.314   0.414
90    D        -0.992  -1.063  -1.047  -1.104  -1.238  -1.219  -0.841  -0.909  -0.862
91    K        -0.601  -0.706  -0.623  -0.829  -0.927  -0.832  -0.674  -0.772  -0.664
92    I         0.348   0.337   0.165   0.533   0.527   0.285   0.327   0.301   0.041
93    K        -0.601  -0.575  -0.588  -0.549  -0.458  -0.515  -0.674  -0.624  -0.622
94    V         1.920   1.965   2.080   1.993   2.062   2.246   2.162   2.232   2.438
95    E        -1.530  -1.474  -1.443  -1.601  -1.514  -1.464  -1.175  -1.111  -1.042
96    W        -1.139  -1.178  -1.098  -0.632  -0.653  -0.541  -1.008  -1.026  -0.914
97    L        -0.601  -0.569  -0.612  -0.599  -0.555  -0.615  -0.674  -0.643  -0.654
98    A        -0.705  -0.740  -0.641  -0.746  -0.842  -0.676  -0.790  -0.815  -0.684
99    L        -0.705  -0.661  -0.624  -0.691  -0.610  -0.557  -0.790  -0.728  -0.665
100   E         0.664   0.709   0.757   0.123   0.185   0.224   0.345   0.416   0.449
101   S        -0.532  -0.564  -0.576  -0.561  -0.590  -0.594  -0.563  -0.606  -0.602
102   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
103   E        -0.992  -1.046  -1.032  -1.082  -1.123  -1.118  -0.841  -0.893  -0.847
104   M        -1.139  -1.028  -1.053  -1.097  -0.995  -0.942  -1.008  -0.896  -0.875
105   Y        -1.530  -1.546  -1.477  -1.337  -1.377  -1.308  -1.175  -1.173  -1.070
106   D        -1.530  -1.472  -1.439  -1.398  -1.376  -1.253  -1.175  -1.110  -1.039
107   T        -0.992  -0.794  -0.991  -0.585  -0.302  -0.579  -0.841  -0.610  -0.804
108   R         0.348   0.490   0.202   0.639   0.837   0.422   0.327   0.537   0.099
109   D         1.110   1.015   0.967   0.979   0.861   0.787   1.161   0.992   0.870
110   F         0.739   0.658   0.740   0.730   0.578   0.696   0.494   0.314   0.414
111   S        -1.139  -1.124  -1.064  -0.860  -0.839  -0.733  -1.008  -0.978  -0.884
112   I         1.110   1.015   0.967   1.214   1.109   1.031   1.161   0.992   0.870
113   T         0.348   0.153   0.106   0.673   0.409   0.330   0.327   0.037  -0.048
114   F        -0.748  -0.700  -0.642  -0.743  -0.679  -0.586  -0.841  -0.782  -0.688
115   H        -0.748  -0.699  -0.641  -0.706  -0.679  -0.572  -0.841  -0.778  -0.686
116   F         1.920   1.965   2.080   1.965   2.028   2.218   2.162   2.232   2.438
117   H        -1.530  -1.534  -1.466  -1.049  -1.051  -0.953  -1.175  -1.164  -1.061
118   G        -1.530  -1.456  -1.441  -1.680  -1.569  -1.549  -1.175  -1.097  -1.041
119   I        -0.062   0.007  -0.006  -0.107   0.033  -0.013  -0.341  -0.240  -0.238
120   E         0.207   0.372   0.145  -0.144   0.091  -0.285   0.118   0.364   0.011
121   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
122   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
123   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
124   G        -0.162  -0.105  -0.082  -0.209  -0.115  -0.123  -0.454  -0.377  -0.339
125   D        -0.062   0.007  -0.006  -0.240  -0.084  -0.107  -0.341  -0.240  -0.238
126   F        -0.601  -0.551  -0.579  -0.530  -0.472  -0.499  -0.674  -0.616  -0.618
127   K        -1.139  -1.168  -1.094  -1.096  -1.147  -1.021  -1.008  -1.018  -0.910
128   E        -0.601  -0.558  -0.600  -0.921  -0.899  -0.882  -0.674  -0.632  -0.641
129   Q         0.348   0.153   0.106   0.584   0.274   0.148   0.327   0.037  -0.048
130   Q        -1.530  -1.508  -1.469  -1.254  -1.227  -1.089  -1.175  -1.144  -1.063
131   V         0.034   0.009  -0.011   0.065  -0.015  -0.032  -0.174  -0.237  -0.243
132   T         0.034   0.018   0.033   0.069   0.045   0.025  -0.174  -0.173  -0.171
133   K         1.110   1.020   0.982   0.993   0.894   0.819   1.161   1.001   0.898
134   V         0.034   0.050   0.003   0.058   0.062  -0.005  -0.174  -0.164  -0.223
135   F         1.110   1.020   0.982   1.219   1.094   1.023   1.161   1.001   0.898
136   Q        -0.992  -1.044  -1.032  -0.862  -0.946  -0.880  -0.841  -0.891  -0.846
137   I        -0.601  -0.616  -0.588  -0.562  -0.574  -0.542  -0.674  -0.690  -0.628
138   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
139   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
140   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
141   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
142   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
143   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
144   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
145   -        -0.816  -0.783  -0.685  -0.717  -0.657  -0.524  -0.904  -0.856  -0.731
146   K         1.031   1.153   0.939   1.046   1.235   0.882   1.026   1.227   0.816
147   K         0.932   0.931   0.871   0.786   0.804   0.713   0.854   0.840   0.682
148   G        -0.132  -0.162  -0.086  -0.360  -0.503  -0.404  -0.393  -0.442  -0.342
149   -        -0.816  -0.787  -0.685  -1.048  -1.011  -0.863  -0.904  -0.861  -0.731
150   -        -0.132  -0.102  -0.038  -0.152  -0.109  -0.035  -0.393  -0.349  -0.269
151   -        -0.816  -0.787  -0.685  -0.700  -0.659  -0.507  -0.904  -0.861  -0.731
152   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
153   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
154   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
155   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
156   K        -0.816  -0.757  -0.685  -1.277  -1.089  -1.097  -0.904  -0.827  -0.731
157   D         0.552   0.604   0.710   0.118   0.225   0.371   0.118   0.204   0.352
158   D         0.034   0.019   0.031  -0.457  -0.478  -0.496  -0.174  -0.171  -0.173
159   Q        -1.530  -1.508  -1.469  -1.376  -1.363  -1.250  -1.175  -1.144  -1.063
160   E        -0.601  -0.572  -0.577  -0.764  -0.678  -0.759  -0.674  -0.620  -0.609
161   D        -1.139  -1.180  -1.072  -1.363  -1.358  -1.233  -1.008  -1.027  -0.891
162   G        -0.210  -0.186  -0.097  -0.470  -0.415  -0.278  -0.507  -0.476  -0.358
163   I        -1.139  -1.100  -1.070  -1.015  -0.958  -0.905  -1.008  -0.958  -0.889
164   L         0.348   0.297   0.164   0.489   0.431   0.243   0.327   0.247   0.040
165   T        -0.062  -0.013  -0.001   0.024   0.093   0.141  -0.341  -0.276  -0.238
166   S         1.920   1.965   2.080   1.907   1.979   2.158   2.162   2.232   2.438
167   E         0.348   0.296   0.161   0.208   0.129  -0.030   0.327   0.245   0.036
168   P         1.110   1.184   0.998   1.323   1.431   1.181   1.161   1.278   0.929
169   V         1.920   1.965   2.080   1.993   2.062   2.246   2.162   2.232   2.438
170   P        -1.139  -1.052  -1.056  -1.131  -1.009  -1.012  -1.008  -0.916  -0.877
171   I         0.739   0.811   0.807   0.687   0.813   0.775   0.494   0.616   0.553
172   E        -0.992  -0.902  -1.009  -1.013  -0.834  -1.047  -0.841  -0.739  -0.823
173   W         1.920   1.965   2.080   2.158   2.230   2.415   2.162   2.232   2.438
174   P         1.031   0.881   0.896   1.177   0.945   0.933   1.026   0.749   0.732
175   Q         0.207   0.328   0.125   0.219   0.395   0.145   0.118   0.297  -0.020
176   S        -0.076  -0.158  -0.059  -0.335  -0.452  -0.321  -0.336  -0.436  -0.307
177   Y        -0.076  -0.158  -0.059  -0.131  -0.275  -0.156  -0.336  -0.436  -0.307
178   D         0.207   0.259   0.082   0.006   0.080  -0.224   0.118   0.196  -0.086
179   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
180   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
181   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
182   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
183   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
184   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
185   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
186   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
187   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
188   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
189   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
190   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
191   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
192   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
193   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
194   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
195   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
196   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
197   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
198   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
199   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
200   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
201   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
202   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
203   S        -1.161  -1.174  -1.111  -1.159  -1.153  -1.108  -1.017  -1.019  -0.924
204   I         1.031   0.881   0.896   1.111   0.917   0.920   1.026   0.749   0.732
205   N         1.031   0.881   0.896   1.228   1.000   0.984   1.026   0.749   0.732
206   P         1.031   0.881   0.896   1.237   1.031   1.049   1.026   0.749   0.732
207   D        -0.705  -0.628  -0.622  -0.996  -0.904  -0.883  -0.790  -0.697  -0.663
208   L         0.207   0.096   0.051   0.242   0.037  -0.038   0.118  -0.058  -0.134
209   I         1.031   0.881   0.896   1.107   0.910   0.914   1.026   0.749   0.732
210   K        -0.532  -0.548  -0.577  -0.684  -0.669  -0.779  -0.563  -0.587  -0.604
211   D         0.207   0.259   0.082   0.040   0.110  -0.170   0.118   0.196  -0.086
212   K         1.031   1.076   0.940   0.926   1.009   0.824   1.026   1.097   0.818
213   R        -1.617  -1.568  -1.494  -1.232  -1.149  -1.051  -1.244  -1.188  -1.083
214   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
215   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
216   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
217   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
218   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
219   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
220   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
221   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
222   S         0.207   0.117   0.048   0.259   0.091  -0.006   0.118  -0.029  -0.138
223   P        -1.139  -1.131  -1.074  -1.188  -1.225  -1.125  -1.008  -0.984  -0.892
224   E        -0.357  -0.495  -0.534  -0.527  -0.732  -0.799  -0.341  -0.514  -0.551
225   G         0.034  -0.011   0.014  -0.015  -0.071  -0.100  -0.174  -0.219  -0.200
226   K         1.110   1.015   0.967   0.999   0.897   0.807   1.161   0.992   0.870
227   K         0.348   0.153   0.106   0.335   0.096   0.013   0.327   0.037  -0.048
228   K        -0.992  -1.014  -1.032  -0.729  -0.765  -0.847  -0.841  -0.862  -0.847
229   Y         0.348   0.153   0.106   0.582   0.286   0.172   0.327   0.037  -0.048
230   R         1.110   1.015   0.967   1.320   1.191   1.097   1.161   0.992   0.870
231   Q        -1.139  -1.178  -1.098  -0.979  -1.059  -0.930  -1.008  -1.026  -0.914
232   G         1.110   1.020   0.982   1.353   1.251   1.207   1.161   1.001   0.898
233   M         0.348   0.153   0.106   0.718   0.431   0.306   0.327   0.037  -0.048
234   K         1.110   1.015   0.967   1.022   0.928   0.853   1.161   0.992   0.870
235   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
236   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
237   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
238   T         0.034   0.023   0.046   0.105   0.121   0.150  -0.174  -0.165  -0.150
239   I         1.110   1.237   1.008   1.253   1.418   1.128   1.161   1.364   0.949
240   F         1.920   1.965   2.080   1.965   2.028   2.218   2.162   2.232   2.438
241   G        -0.748  -0.758  -0.648  -0.746  -0.771  -0.615  -0.841  -0.831  -0.693
242   W         1.110   1.020   0.982   1.465   1.363   1.315   1.161   1.001   0.898
243   F         1.920   1.965   2.080   1.965   2.028   2.218   2.162   2.232   2.438
244   R        -1.139  -1.167  -1.090  -0.926  -0.919  -0.815  -1.008  -1.017  -0.907
245   W         1.110   1.015   0.967   1.465   1.356   1.291   1.161   0.992   0.870
246   T         1.110   1.015   0.967   1.370   1.259   1.201   1.161   0.992   0.870
247   G         1.920   1.965   2.080   2.042   2.112   2.296   2.162   2.232   2.438
248   L        -1.139  -1.108  -1.075  -1.270  -1.231  -1.169  -1.008  -0.965  -0.893
249   K         0.348   0.153   0.106   0.268  -0.005  -0.113   0.327   0.037  -0.048
250   P         0.348   0.153   0.106   0.579   0.281   0.173   0.327   0.037  -0.048
251   G         0.348   0.153   0.106   0.585   0.295   0.182   0.327   0.037  -0.048
252   K         0.348   0.153   0.106   0.272   0.007  -0.104   0.327   0.037  -0.048
253   E         1.110   1.020   0.982   0.833   0.687   0.630   1.161   1.001   0.898
254   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
255   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
256   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
257   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
258   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
259   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
260   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
261   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
262   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
263   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
264   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
265   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
266   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
267   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
268   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
269   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
270   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
271   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
272   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
273   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
274   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
275   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
276   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
277   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
278   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
279   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
280   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
281   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
282   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
283   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
284   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
285   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
286   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
287   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
288   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
289   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
290   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
291   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
292   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
293   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
294   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
295   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
296   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
297   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
298   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
299   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
300   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
301   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
302   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
303   F         1.920   1.965   2.080   1.965   2.028   2.218   2.162   2.232   2.438
304   P         0.664   0.709   0.757   0.697   0.766   0.826   0.345   0.416   0.449
305   H        -0.748  -0.681  -0.647  -0.665  -0.624  -0.537  -0.841  -0.755  -0.692
306   G         1.920   1.965   2.080   2.042   2.112   2.296   2.162   2.232   2.438
307   D         0.348   0.297   0.164   0.231   0.165  -0.066   0.327   0.247   0.040
308   S        -0.992  -0.969  -1.018  -0.903  -0.853  -0.990  -0.841  -0.809  -0.833
309   L         1.920   1.965   2.080   1.872   1.937   2.123   2.162   2.232   2.438
310   A         0.739   0.724   0.766   0.776   0.745   0.798   0.494   0.446   0.468
311   S        -1.530  -1.528  -1.458  -1.122  -1.137  -1.022  -1.175  -1.159  -1.054
312   L         0.348   0.153   0.106   0.486   0.218   0.149   0.327   0.037  -0.048
313   F        -0.062   0.007  -0.006  -0.163  -0.067  -0.067  -0.341  -0.240  -0.238
314   S        -0.357  -0.360  -0.478  -0.122  -0.119  -0.283  -0.341  -0.343  -0.480
315   E         0.739   0.721   0.749   0.247   0.180   0.194   0.494   0.441   0.434
316   E         0.739   0.852   0.826   0.312   0.503   0.403   0.494   0.694   0.592
317   I         0.739   0.869   0.844   0.614   0.825   0.763   0.494   0.727   0.629
318   Y         0.034  -0.069  -0.012   0.208   0.075   0.150  -0.174  -0.314  -0.244
319   P         1.110   1.184   0.998   1.318   1.425   1.171   1.161   1.278   0.929
320   F        -0.601  -0.615  -0.588  -0.332  -0.344  -0.298  -0.674  -0.690  -0.628
321   C         0.572   0.656   0.736   0.595   0.719   0.841   0.160   0.311   0.406
322   V         0.348   0.293   0.149   0.573   0.502   0.274   0.327   0.241   0.017
323   K         1.920   1.965   2.080   1.713   1.797   1.960   2.162   2.232   2.438
324   Y         1.920   1.965   2.080   2.048   2.125   2.302   2.162   2.232   2.438
325   Y         0.739   0.658   0.740   0.798   0.646   0.751   0.494   0.314   0.414
326   A         0.348   0.493   0.202   0.660   0.861   0.461   0.327   0.541   0.099
327   E         0.348   0.293   0.149   0.210   0.130  -0.043   0.327   0.241   0.017
328   A         1.920   1.965   2.080   1.987   2.052   2.240   2.162   2.232   2.438
329   Q         0.034  -0.007   0.018   0.200   0.171   0.196  -0.174  -0.214  -0.194
330   R        -0.992  -1.073  -1.066  -0.676  -0.845  -0.837  -0.841  -0.919  -0.881
331   D        -0.992  -1.073  -1.066  -0.971  -1.115  -1.057  -0.841  -0.919  -0.881
332   L        -0.748  -0.673  -0.652  -1.152  -1.096  -1.013  -0.841  -0.749  -0.696
333   E        -0.992  -1.063  -1.047  -0.964  -1.076  -0.975  -0.841  -0.909  -0.862
334   D        -0.357  -0.497  -0.536  -0.381  -0.577  -0.641  -0.341  -0.515  -0.553
335   E        -0.062  -0.102  -0.028  -0.589  -0.626  -0.511  -0.341  -0.371  -0.268
336   E        -0.062   0.002  -0.013  -0.589  -0.517  -0.501  -0.341  -0.260  -0.252
337   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
338   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
339   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
340   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
341   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
342   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
343   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
344   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
345   G        -1.161  -1.183  -1.105  -1.125  -1.176  -1.102  -1.017  -1.027  -0.918
346   D         1.031   1.054   0.949   0.898   0.936   0.805   1.026   1.059   0.834
347   S        -0.705  -0.757  -0.641  -0.882  -0.950  -0.789  -0.790  -0.829  -0.684
348   E         1.031   1.161   0.973   0.753   0.911   0.676   1.026   1.240   0.881
349   D         0.572   0.604   0.704  -0.075  -0.048   0.106   0.160   0.205   0.340
350   D         1.920   1.965   2.080   1.694   1.760   1.940   2.162   2.232   2.438
351   D        -1.139  -1.111  -1.063  -1.212  -1.231  -1.101  -1.008  -0.969  -0.883
352   G        -1.139  -1.107  -1.063  -1.222  -1.238  -1.113  -1.008  -0.964  -0.884
353   S        -0.601  -0.575  -0.588  -0.904  -0.902  -0.887  -0.674  -0.624  -0.622
354   L        -1.139  -1.104  -1.073  -1.230  -1.240  -1.158  -1.008  -0.963  -0.891
355   G        -0.992  -1.031  -1.039  -1.128  -1.224  -1.188  -0.841  -0.879  -0.854
356   E         0.034   0.096   0.022  -0.372  -0.332  -0.396  -0.174  -0.106  -0.196
357   V         0.034   0.048  -0.001  -0.159  -0.244  -0.259  -0.174  -0.194  -0.227
358   D         1.920   1.965   2.080   1.694   1.760   1.940   2.162   2.232   2.438
359   L        -0.357  -0.497  -0.536  -0.344  -0.616  -0.711  -0.341  -0.515  -0.553
360   P         0.034   0.163   0.060  -0.266  -0.108  -0.206  -0.174   0.010  -0.130
361   L        -0.992  -0.915  -0.988  -1.128  -1.026  -1.121  -0.841  -0.753  -0.801
362   S        -0.601  -0.446  -0.558  -0.936  -0.695  -0.863  -0.674  -0.479  -0.591
363   -        -0.532  -0.517  -0.551  -0.722  -0.725  -0.775  -0.563  -0.538  -0.572
364   -        -0.705  -0.687  -0.622  -1.095  -1.079  -0.958  -0.790  -0.759  -0.664
365   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
366   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
367   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
368   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
369   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
370   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
371   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
372   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
373   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
374   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
375   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
376   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
377   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
378   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
379   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
380   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
381   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
382   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
383   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
384   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
385   D        -0.601  -0.595  -0.557  -0.777  -0.769  -0.706  -0.674  -0.648  -0.588
386   E        -0.992  -1.063  -1.047  -1.173  -1.251  -1.259  -0.841  -0.909  -0.862
387   E        -0.601  -0.612  -0.589  -0.589  -0.610  -0.501  -0.674  -0.671  -0.628
388   P        -0.357  -0.190  -0.439  -0.046   0.199  -0.175  -0.341  -0.117  -0.431
389   S        -1.530  -1.528  -1.453  -1.227  -1.198  -1.108  -1.175  -1.159  -1.050
390   S         0.739   0.747   0.769   0.457   0.482   0.474   0.494   0.491   0.475
391   K         1.920   1.965   2.080   1.713   1.797   1.960   2.162   2.232   2.438
392   K        -0.601  -0.534  -0.562  -0.613  -0.509  -0.527  -0.674  -0.596  -0.599
393   R         0.034   0.036   0.056  -0.103  -0.071  -0.059  -0.174  -0.144  -0.133
394   K         0.810   0.884   0.817   0.553   0.671   0.533   0.629   0.754   0.573
395   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
396   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
397   V        -1.257  -1.210  -1.130  -0.978  -0.904  -0.792  -1.108  -1.051  -0.942
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P53853
Output conservation file - output/P53853
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
