1     M        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
2     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    M        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
19    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
20    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
21    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
22    H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
23    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
24    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
25    Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
26    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
27    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
28    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
29    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
30    W        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
31    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
32    V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
33    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
34    I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
35    T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
36    G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
37    Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
38    I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
39    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
40    M         0.269   0.387   0.147   0.635   0.827   0.430   0.193   0.372  -0.007
41    D         1.079   1.152   0.986   1.225   1.348   1.074   1.095   1.215   0.894
42    F        -0.911  -0.900  -0.948  -0.475  -0.436  -0.510  -0.760  -0.747  -0.779
43    D         0.792   0.719   0.761   0.702   0.500   0.527   0.566   0.400   0.440
44    N        -0.526  -0.500  -0.518  -0.824  -0.783  -0.802  -0.594  -0.549  -0.565
45    L         0.098   0.105   0.045  -0.122  -0.117  -0.188  -0.097  -0.109  -0.183
46    L         0.407   0.232   0.166   0.371   0.139   0.044   0.400   0.136   0.023
47    N        -0.287  -0.380  -0.454  -0.123  -0.278  -0.407  -0.263  -0.388  -0.472
48    L         1.954   2.002   2.075   1.775   1.843   1.962   2.223   2.304   2.440
49    E         1.954   2.002   2.075   1.704   1.757   1.890   2.223   2.304   2.440
50    E         1.157   1.233   1.041   0.964   1.056   0.800   1.229   1.352   1.000
51    Q        -0.526  -0.603  -0.546  -0.865  -0.976  -0.894  -0.594  -0.664  -0.592
52    Y        -0.526  -0.554  -0.533  -0.468  -0.541  -0.510  -0.594  -0.613  -0.582
53    Y         1.954   2.002   2.075   2.182   2.248   2.375   2.223   2.304   2.440
54    Q        -0.526  -0.580  -0.553  -0.716  -0.841  -0.790  -0.594  -0.653  -0.605
55    E        -0.287  -0.333  -0.450  -0.476  -0.539  -0.744  -0.263  -0.326  -0.467
56    G         1.954   2.002   2.075   2.016   2.082   2.207   2.223   2.304   2.440
57    F         0.792   0.884   0.824   0.906   1.055   0.932   0.566   0.728   0.571
58    L        -0.911  -0.963  -0.962  -1.184  -1.246  -1.288  -0.760  -0.815  -0.793
59    E         1.157   1.121   1.020   0.984   0.927   0.801   1.229   1.163   0.959
60    G         1.954   2.002   2.075   2.016   2.082   2.207   2.223   2.304   2.440
61    Q        -0.526  -0.614  -0.548  -0.520  -0.649  -0.577  -0.594  -0.679  -0.596
62    N        -0.911  -0.987  -0.993  -0.821  -0.970  -0.995  -0.760  -0.838  -0.825
63    E        -0.911  -0.987  -0.993  -1.032  -1.161  -1.127  -0.760  -0.838  -0.825
64    N         0.003   0.070   0.039  -0.102   0.001  -0.023  -0.263  -0.172  -0.195
65    I        -0.142  -0.111  -0.059  -0.321  -0.254  -0.218  -0.428  -0.387  -0.324
66    K         1.157   1.036   1.009   1.140   0.935   0.880   1.229   1.012   0.939
67    Q        -0.911  -0.853  -0.924  -0.612  -0.514  -0.615  -0.760  -0.691  -0.753
68    S        -0.672  -0.600  -0.600  -0.752  -0.642  -0.631  -0.760  -0.680  -0.656
69    F        -0.142  -0.088  -0.056  -0.288  -0.177  -0.170  -0.428  -0.353  -0.319
70    L        -0.911  -0.958  -0.957  -1.063  -1.178  -1.150  -0.760  -0.810  -0.788
71    E         1.954   2.002   2.075   1.704   1.757   1.890   2.223   2.304   2.440
72    G         1.157   1.036   1.009   1.310   1.147   1.122   1.229   1.012   0.939
73    K         0.407   0.232   0.166   0.528   0.285   0.194   0.400   0.136   0.023
74    Q         0.098   0.050   0.074  -0.314  -0.408  -0.380  -0.097  -0.147  -0.133
75    Y         0.627   0.641   0.718   0.593   0.600   0.716   0.234   0.238   0.349
76    G         1.954   2.002   2.075   2.016   2.082   2.207   2.223   2.304   2.440
77    L         0.098   0.093   0.081  -0.077  -0.075  -0.084  -0.097  -0.091  -0.117
78    Q         1.157   1.036   1.009   1.231   1.045   0.972   1.229   1.012   0.939
79    V         0.003  -0.059   0.014   0.135   0.083   0.192  -0.263  -0.327  -0.231
80    G         1.157   1.036   1.009   1.310   1.147   1.122   1.229   1.012   0.939
81    F         0.792   0.719   0.761   0.878   0.743   0.794   0.566   0.400   0.440
82    Q         1.157   1.036   1.009   1.285   1.129   1.071   1.229   1.012   0.939
83    R         1.157   1.036   1.009   1.454   1.282   1.225   1.229   1.012   0.939
84    F         1.157   1.036   1.009   1.419   1.265   1.224   1.229   1.012   0.939
85    T        -0.287  -0.107  -0.396  -0.313  -0.060  -0.461  -0.263  -0.022  -0.398
86    L         0.098   0.093   0.081  -0.146  -0.135  -0.158  -0.097  -0.091  -0.117
87    L         0.098   0.030   0.063  -0.125  -0.198  -0.151  -0.097  -0.179  -0.145
88    G         1.954   2.002   2.075   2.016   2.082   2.207   2.223   2.304   2.440
89    Q        -1.056  -1.102  -1.043  -1.139  -1.276  -1.191  -0.926  -0.957  -0.877
90    M         0.098   0.133   0.091   0.132   0.195   0.101  -0.097  -0.025  -0.104
91    E        -0.672  -0.613  -0.593  -0.858  -0.744  -0.726  -0.760  -0.697  -0.652
92    G         1.157   1.223   1.052   1.225   1.317   1.045   1.229   1.335   1.021
93    L        -0.526  -0.474  -0.539  -0.580  -0.479  -0.545  -0.594  -0.548  -0.590
94    C        -0.526  -0.419  -0.494  -0.169  -0.015  -0.103  -0.594  -0.450  -0.530
95    D        -0.526  -0.624  -0.563  -0.415  -0.516  -0.439  -0.594  -0.691  -0.612
96    V         0.098   0.105   0.045   0.236   0.228   0.150  -0.097  -0.109  -0.183
97    -         1.954   2.002   2.075   2.305   2.379   2.500   2.223   2.304   2.440
98    -        -0.066  -0.027   0.007  -0.489  -0.482  -0.406  -0.315  -0.262  -0.224
99    -        -0.739  -0.711  -0.639  -0.976  -0.996  -0.834  -0.822  -0.787  -0.697
100   -        -0.739  -0.711  -0.639  -0.884  -0.887  -0.740  -0.822  -0.787  -0.697
101   I        -0.526  -0.614  -0.548  -0.743  -0.896  -0.813  -0.594  -0.679  -0.596
102   E        -1.056  -1.103  -1.007  -1.121  -1.165  -1.030  -0.926  -0.958  -0.845
103   S        -0.526  -0.512  -0.519  -0.439  -0.393  -0.438  -0.594  -0.567  -0.565
104   Y        -0.011  -0.072   0.002  -0.121  -0.245  -0.144  -0.258  -0.339  -0.243
105   G        -1.825  -1.796  -1.735  -1.601  -1.465  -1.469  -1.257  -1.225  -1.145
106   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
107   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
108   L        -1.077  -1.107  -1.050  -1.018  -1.012  -0.929  -0.935  -0.956  -0.881
109   H        -0.911  -0.774  -0.913  -0.847  -0.647  -0.859  -0.760  -0.599  -0.741
110   S        -1.056  -1.103  -1.007  -0.913  -0.968  -0.839  -0.926  -0.958  -0.845
111   P        -1.441  -1.365  -1.377  -1.164  -1.082  -1.056  -1.091  -1.015  -1.000
112   T        -0.526  -0.471  -0.534  -0.391  -0.373  -0.403  -0.594  -0.545  -0.585
113   L         0.407   0.232   0.166   0.390   0.157   0.076   0.400   0.136   0.023
114   E        -1.441  -1.432  -1.414  -1.136  -1.069  -1.121  -1.091  -1.078  -1.030
115   K        -0.526  -0.624  -0.563  -0.668  -0.805  -0.740  -0.594  -0.691  -0.612
116   N         0.003  -0.008   0.016   0.127   0.156   0.185  -0.263  -0.264  -0.227
117   I         0.003   0.067   0.040  -0.258  -0.188  -0.191  -0.263  -0.175  -0.196
118   H        -1.825  -1.796  -1.735  -1.599  -1.644  -1.467  -1.257  -1.225  -1.145
119   T        -0.526  -0.399  -0.495  -0.474  -0.267  -0.414  -0.594  -0.435  -0.539
120   I         0.003   0.079   0.029  -0.279  -0.188  -0.219  -0.263  -0.173  -0.213
121   R        -0.526  -0.416  -0.494  -0.580  -0.420  -0.547  -0.594  -0.446  -0.530
122   T        -1.056  -1.086  -1.007  -1.091  -1.109  -1.002  -0.926  -0.945  -0.845
123   L         1.157   1.223   1.052   1.039   1.133   0.896   1.229   1.335   1.021
124   M        -0.526  -0.549  -0.532  -0.433  -0.488  -0.446  -0.594  -0.609  -0.581
125   K        -1.441  -1.362  -1.373  -1.390  -1.294  -1.274  -1.091  -1.013  -0.997
126   G        -1.056  -0.976  -0.996  -1.070  -0.923  -0.992  -0.926  -0.845  -0.835
127   L        -0.526  -0.544  -0.528  -0.674  -0.751  -0.709  -0.594  -0.614  -0.579
128   K        -1.056  -0.980  -1.004  -1.021  -0.883  -0.932  -0.926  -0.848  -0.842
129   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
130   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
131   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
132   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
133   M        -0.672  -0.636  -0.597  -0.671  -0.613  -0.562  -0.760  -0.716  -0.655
134   N        -0.526  -0.514  -0.519  -0.383  -0.344  -0.355  -0.594  -0.569  -0.560
135   N         1.954   2.002   2.075   2.039   2.121   2.230   2.223   2.304   2.440
136   D        -1.056  -1.050  -1.020  -1.127  -1.161  -1.100  -0.926  -0.914  -0.856
137   D        -1.441  -1.448  -1.385  -1.333  -1.367  -1.273  -1.091  -1.090  -1.007
138   E         0.407   0.394   0.228   0.244   0.215  -0.025   0.400   0.380   0.119
139   S        -0.526  -0.471  -0.534  -0.750  -0.677  -0.727  -0.594  -0.518  -0.580
140   V         1.157   1.036   1.009   1.427   1.271   1.234   1.229   1.012   0.939
141   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
142   M        -1.056  -1.013  -0.997  -0.974  -0.881  -0.862  -0.926  -0.877  -0.836
143   E        -1.441  -1.453  -1.388  -1.515  -1.524  -1.416  -1.091  -1.094  -1.009
144   F         0.003   0.077   0.045  -0.006   0.104   0.048  -0.263  -0.177  -0.193
145   E         1.157   1.036   1.009   0.984   0.808   0.785   1.229   1.012   0.939
146   R        -0.287  -0.377  -0.451  -0.107  -0.238  -0.320  -0.263  -0.384  -0.469
147   V        -1.825  -1.796  -1.735  -1.259  -1.190  -1.121  -1.257  -1.225  -1.145
148   L        -0.526  -0.603  -0.546  -0.517  -0.546  -0.492  -0.594  -0.664  -0.592
149   I        -1.441  -1.389  -1.383  -1.263  -1.194  -1.168  -1.091  -1.040  -1.005
150   K         1.954   2.002   2.075   1.931   1.993   2.121   2.223   2.304   2.440
151   L        -0.672  -0.626  -0.594  -0.816  -0.719  -0.675  -0.760  -0.707  -0.651
152   K         0.003  -0.063   0.018  -0.030  -0.103   0.017  -0.263  -0.334  -0.227
153   N         0.792   0.719   0.761   0.805   0.680   0.735   0.566   0.400   0.440
154   K         1.954   2.002   2.075   1.931   1.993   2.121   2.223   2.304   2.440
155   F        -0.526  -0.624  -0.563  -0.517  -0.634  -0.551  -0.594  -0.691  -0.612
156   R         1.157   1.036   1.009   1.454   1.282   1.225   1.229   1.012   0.939
157   T        -0.142  -0.088  -0.056  -0.288  -0.177  -0.163  -0.428  -0.353  -0.319
158   I         0.098   0.023   0.035   0.064  -0.061  -0.073  -0.097  -0.210  -0.199
159   L         0.003  -0.059   0.014  -0.138  -0.192  -0.081  -0.263  -0.327  -0.231
160   I        -1.441  -1.358  -1.374  -1.154  -0.987  -1.060  -1.091  -1.008  -0.997
161   T        -0.526  -0.534  -0.536  -0.449  -0.487  -0.475  -0.594  -0.597  -0.580
162   L        -0.911  -0.851  -0.935  -0.816  -0.737  -0.813  -0.760  -0.688  -0.764
163   H        -0.672  -0.602  -0.599  -0.674  -0.593  -0.561  -0.760  -0.682  -0.655
164   R        -1.056  -1.102  -1.043  -1.068  -1.113  -1.019  -0.926  -0.957  -0.877
165   L        -1.056  -1.069  -1.011  -1.449  -1.481  -1.366  -0.926  -0.928  -0.849
166   V        -0.634  -0.616  -0.614  -0.361  -0.328  -0.374  -0.700  -0.674  -0.668
167   K         0.982   0.993   0.886   0.978   0.997   0.817   0.924   0.933   0.697
168   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
169   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
170   R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
171   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
172   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
173   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
174   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
175   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
176   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
177   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
178   F        -1.056  -1.027  -1.012  -1.048  -0.999  -1.007  -0.926  -0.887  -0.848
179   E        -1.056  -1.102  -1.014  -1.250  -1.336  -1.177  -0.926  -0.957  -0.851
180   V        -1.056  -1.054  -1.006  -0.878  -0.831  -0.782  -0.926  -0.917  -0.844
181   F        -0.526  -0.562  -0.542  -0.544  -0.567  -0.548  -0.594  -0.626  -0.588
182   E         0.792   0.862   0.866   0.453   0.546   0.558   0.566   0.686   0.656
183   D        -0.526  -0.565  -0.538  -0.413  -0.479  -0.446  -0.594  -0.629  -0.588
184   V         0.407   0.368   0.220   0.340   0.274   0.071   0.400   0.328   0.107
185   S         0.108   0.133   0.026   0.311   0.357   0.178  -0.051  -0.015  -0.194
186   R         0.647   0.679   0.740   0.536   0.583   0.659   0.274   0.317   0.396
187   A         0.647   0.687   0.746   0.356   0.410   0.508   0.274   0.335   0.408
188   I         0.982   1.003   0.890   1.034   1.066   0.881   0.924   0.950   0.704
189   A         0.647   0.679   0.740   0.652   0.695   0.778   0.274   0.317   0.396
190   G         1.954   2.002   2.075   2.043   2.109   2.235   2.223   2.304   2.440
191   E        -0.634  -0.630  -0.609  -0.898  -0.889  -0.851  -0.700  -0.691  -0.662
192   I         0.717   0.788   0.803   0.386   0.491   0.503   0.419   0.539   0.527
193   R        -0.066   0.007  -0.013  -0.077   0.056   0.011  -0.315  -0.208  -0.253
194   G         1.954   2.002   2.075   2.052   2.102   2.244   2.223   2.304   2.440
195   F         0.607   0.653   0.724   0.564   0.647   0.754   0.193   0.264   0.362
196   V         0.607   0.653   0.724   0.528   0.601   0.710   0.193   0.264   0.362
197   E         1.954   2.002   2.075   1.776   1.824   1.963   2.223   2.304   2.440
198   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
199   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
200   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
201   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
202   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
203   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
204   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
205   K        -0.095  -0.084  -0.049  -0.433  -0.419  -0.405  -0.375  -0.359  -0.311
206   T         0.647   0.679   0.740   0.646   0.695   0.779   0.274   0.317   0.396
207   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
208   K        -1.441  -1.432  -1.414  -1.193  -1.206  -1.177  -1.091  -1.078  -1.030
209   Q         0.003  -0.059   0.014  -0.327  -0.407  -0.288  -0.263  -0.327  -0.231
210   N         0.792   0.888   0.845   0.771   0.937   0.839   0.566   0.734   0.614
211   Q        -0.459  -0.481  -0.546  -0.304  -0.344  -0.422  -0.484  -0.511  -0.587
212   A        -0.526  -0.487  -0.534  -0.398  -0.353  -0.428  -0.594  -0.530  -0.579
213   Q        -0.526  -0.538  -0.538  -0.425  -0.424  -0.433  -0.594  -0.593  -0.584
214   S        -1.441  -1.432  -1.414  -0.957  -0.950  -0.930  -1.091  -1.078  -1.030
215   W         0.407   0.232   0.166   0.825   0.533   0.401   0.400   0.136   0.023
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P53846
Output conservation file - output/P53846
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
