1     M         1.799   1.855   1.964   2.151   2.241   2.419   1.981   2.073   2.259
2     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     A         0.033   0.071   0.000   0.075   0.131  -0.031  -0.157  -0.102  -0.232
5     P        -0.677  -0.620  -0.580  -0.711  -0.625  -0.584  -0.768  -0.694  -0.640
6     S        -0.161  -0.112  -0.047  -0.277  -0.218  -0.089  -0.462  -0.396  -0.310
7     M        -0.677  -0.652  -0.604  -0.561  -0.508  -0.504  -0.768  -0.733  -0.668
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    I        -0.677  -0.604  -0.575  -0.690  -0.589  -0.530  -0.768  -0.673  -0.634
11    P        -0.161  -0.166  -0.069  -0.530  -0.540  -0.395  -0.462  -0.464  -0.339
12    F        -0.161  -0.135  -0.054  -0.002   0.055   0.180  -0.462  -0.424  -0.318
13    T        -1.192  -1.171  -1.048  -0.993  -0.958  -0.776  -1.073  -1.041  -0.896
14    I        -1.101  -1.091  -1.025  -1.196  -1.182  -1.115  -0.988  -0.971  -0.874
15    K         0.511   0.551   0.668   0.185   0.257   0.431   0.072   0.127   0.290
16    L         1.799   1.855   1.964   1.564   1.638   1.822   1.981   2.073   2.259
17    K         0.961   0.857   0.862   0.883   0.743   0.737   0.921   0.725   0.685
18    T         0.187   0.068   0.051   0.430   0.239   0.181   0.072  -0.110  -0.155
19    C        -0.672  -0.572  -0.573  -0.526  -0.378  -0.401  -0.776  -0.662  -0.637
20    L         1.799   1.855   1.964   1.564   1.638   1.822   1.981   2.073   2.259
21    K         1.799   1.855   1.964   1.680   1.774   1.940   1.981   2.073   2.259
22    M         0.754   0.668   0.709   0.908   0.713   0.673   0.549   0.364   0.375
23    C         0.126   0.257   0.079   0.161   0.338   0.113  -0.047   0.145  -0.120
24    I         0.432   0.322   0.154   0.612   0.444   0.183   0.430   0.260   0.003
25    Q        -0.534  -0.509  -0.535  -0.456  -0.431  -0.445  -0.644  -0.603  -0.598
26    R         0.754   0.851   0.821   0.733   0.901   0.798   0.549   0.713   0.604
27    L         1.099   0.950   0.921   0.945   0.747   0.693   1.146   0.891   0.798
28    R         0.432   0.320   0.168   0.621   0.431   0.157   0.430   0.257   0.024
29    Y        -0.978  -1.043  -0.996  -0.636  -0.725  -0.689  -0.882  -0.930  -0.849
30    A        -0.656  -0.713  -0.596  -0.878  -1.000  -0.814  -0.763  -0.805  -0.663
31    Q         1.099   0.950   0.921   1.393   1.196   1.147   1.146   0.891   0.798
32    E        -0.656  -0.666  -0.581  -0.896  -0.898  -0.771  -0.763  -0.764  -0.650
33    K         1.099   1.100   0.942   1.067   1.107   0.862   1.146   1.146   0.839
34    Q        -0.656  -0.663  -0.588  -0.850  -0.894  -0.797  -0.763  -0.761  -0.655
35    Q        -0.212  -0.214  -0.092  -0.309  -0.372  -0.184  -0.524  -0.526  -0.370
36    A         1.799   1.855   1.964   1.779   1.853   2.041   1.981   2.073   2.259
37    I         0.754   0.855   0.777   0.437   0.599   0.445   0.549   0.720   0.516
38    A         0.754   0.851   0.821   0.685   0.825   0.783   0.549   0.713   0.604
39    K         1.799   1.855   1.964   1.693   1.805   1.953   1.981   2.073   2.259
40    Q        -0.196  -0.123  -0.405   0.165   0.278  -0.159  -0.166  -0.067  -0.425
41    S        -0.455  -0.491  -0.526  -0.270  -0.338  -0.388  -0.524  -0.554  -0.582
42    R         1.799   1.855   1.964   1.944   2.026   2.209   1.981   2.073   2.259
43    R         1.799   1.855   1.964   1.944   2.026   2.209   1.981   2.073   2.259
44    Q        -0.978  -1.028  -0.971  -0.925  -1.006  -0.945  -0.882  -0.918  -0.828
45    V        -0.133  -0.073  -0.034  -0.221  -0.096  -0.079  -0.405  -0.319  -0.284
46    A         1.099   1.209   0.966   1.148   1.288   0.977   1.146   1.319   0.885
47    Q        -1.299  -1.277  -1.303  -1.164  -1.175  -1.259  -1.001  -0.976  -0.956
48    L         1.099   0.950   0.921   0.972   0.791   0.756   1.146   0.891   0.798
49    L         1.799   1.855   1.964   1.581   1.667   1.839   1.981   2.073   2.259
50    L        -1.743  -1.736  -1.646  -1.688  -1.726  -1.587  -1.240  -1.222  -1.099
51    T        -1.743  -1.736  -1.665  -1.459  -1.461  -1.366  -1.240  -1.221  -1.112
52    N        -0.196  -0.254  -0.427   0.252   0.178  -0.077  -0.166  -0.247  -0.452
53    K         1.099   0.950   0.921   1.062   0.890   0.816   1.146   0.891   0.798
54    E         1.099   0.950   0.921   1.059   0.840   0.819   1.146   0.891   0.798
55    Q        -0.656  -0.663  -0.588  -0.690  -0.736  -0.621  -0.763  -0.761  -0.655
56    K        -0.012  -0.089  -0.005  -0.284  -0.393  -0.311  -0.286  -0.360  -0.254
57    A         1.099   1.209   0.966   1.148   1.288   0.977   1.146   1.319   0.885
58    H        -0.212  -0.157  -0.068  -0.386  -0.308  -0.164  -0.524  -0.451  -0.337
59    Y        -0.012  -0.089  -0.005  -0.019  -0.132  -0.005  -0.286  -0.360  -0.254
60    R         1.799   1.855   1.964   1.944   2.026   2.209   1.981   2.073   2.259
61    V         0.432   0.336   0.167   0.668   0.526   0.249   0.430   0.279   0.023
62    E         1.799   1.855   1.964   1.685   1.744   1.945   1.981   2.073   2.259
63    T        -0.455  -0.495  -0.526  -0.243  -0.293  -0.338  -0.524  -0.557  -0.581
64    L         0.511   0.551   0.668   0.043   0.096   0.271   0.072   0.127   0.291
65    I         1.799   1.855   1.964   1.879   1.971   2.142   1.981   2.073   2.259
66    H        -0.455  -0.486  -0.526  -0.162  -0.180  -0.211  -0.524  -0.551  -0.582
67    D        -0.196  -0.332  -0.465   0.042  -0.157  -0.339  -0.166  -0.342  -0.501
68    D         1.799   1.855   1.964   1.856   1.936   2.119   1.981   2.073   2.259
69    I         1.099   1.196   0.962   1.202   1.350   0.974   1.146   1.299   0.876
70    H        -0.534  -0.509  -0.535  -0.210  -0.162  -0.186  -0.644  -0.603  -0.598
71    I         0.432   0.458   0.178   0.655   0.710   0.310   0.430   0.471   0.040
72    E         1.799   1.855   1.964   1.685   1.744   1.945   1.981   2.073   2.259
73    L         1.799   1.855   1.964   1.581   1.667   1.839   1.981   2.073   2.259
74    L         1.099   1.100   0.942   0.986   1.006   0.817   1.146   1.146   0.839
75    E         1.799   1.855   1.964   1.685   1.744   1.945   1.981   2.073   2.259
76    I         0.126   0.113   0.047   0.072   0.002  -0.100  -0.047  -0.091  -0.179
77    L         1.799   1.855   1.964   1.581   1.667   1.839   1.981   2.073   2.259
78    E         1.099   0.950   0.921   1.070   0.857   0.845   1.146   0.891   0.798
79    L         1.099   0.950   0.921   0.955   0.762   0.717   1.146   0.891   0.798
80    Y         1.099   0.950   0.921   1.459   1.250   1.197   1.146   0.891   0.798
81    C         1.099   0.950   0.921   1.543   1.355   1.295   1.146   0.891   0.798
82    E         1.799   1.855   1.964   1.685   1.744   1.945   1.981   2.073   2.259
83    L         1.099   0.950   0.921   0.945   0.747   0.693   1.146   0.891   0.798
84    L         1.799   1.855   1.964   1.581   1.667   1.839   1.981   2.073   2.259
85    L         0.126   0.055   0.058  -0.061  -0.170  -0.151  -0.047  -0.127  -0.152
86    A         1.099   0.950   0.921   1.164   0.961   0.935   1.146   0.891   0.798
87    R         1.799   1.855   1.964   1.944   2.026   2.209   1.981   2.073   2.259
88    V        -0.978  -1.033  -0.989  -0.910  -0.945  -0.953  -0.882  -0.923  -0.844
89    Q        -1.743  -1.699  -1.654  -1.349  -1.282  -1.228  -1.240  -1.195  -1.105
90    V        -0.133  -0.160  -0.072  -0.376  -0.433  -0.328  -0.405  -0.449  -0.340
91    I         0.126   0.248   0.087  -0.101   0.077  -0.131  -0.047   0.129  -0.114
92    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
93    D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
94    I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
95    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
96    T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
97    E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
98    E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
99    Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
100   L         0.869   0.882   0.796   0.670   0.710   0.556   0.759   0.770   0.555
101   V        -1.421  -1.325  -1.336  -1.485  -1.369  -1.360  -1.121  -1.025  -0.986
102   K        -0.777  -0.741  -0.621  -1.181  -1.140  -0.964  -0.882  -0.835  -0.688
103   E        -1.421  -1.448  -1.365  -1.308  -1.333  -1.263  -1.121  -1.127  -1.009
104   H        -0.534  -0.588  -0.550  -0.353  -0.449  -0.414  -0.644  -0.688  -0.614
105   M        -0.978  -0.982  -0.966  -0.499  -0.466  -0.449  -0.882  -0.873  -0.823
106   D         0.432   0.348   0.177   0.585   0.463   0.194   0.430   0.294   0.039
107   D        -0.012   0.068   0.015  -0.150  -0.031  -0.116  -0.286  -0.187  -0.231
108   G         0.432   0.348   0.177   0.822   0.698   0.456   0.430   0.294   0.039
109   I        -0.012  -0.089  -0.005  -0.320  -0.369  -0.237  -0.286  -0.360  -0.254
110   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
111   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
112   N        -0.656  -0.626  -0.590  -0.810  -0.822  -0.747  -0.763  -0.734  -0.658
113   E         1.099   0.950   0.921   1.054   0.830   0.808   1.146   0.891   0.798
114   A         1.099   0.950   0.921   1.148   0.937   0.901   1.146   0.891   0.798
115   I        -0.196  -0.242  -0.424  -0.006  -0.118  -0.434  -0.166  -0.234  -0.449
116   R        -1.299  -1.336  -1.340  -0.869  -0.917  -0.893  -1.001  -1.028  -0.988
117   S        -0.455  -0.497  -0.505  -0.346  -0.371  -0.379  -0.524  -0.559  -0.556
118   L        -0.133  -0.128  -0.056  -0.376  -0.359  -0.291  -0.405  -0.405  -0.318
119   I         0.126   0.055   0.058   0.214   0.163   0.144  -0.047  -0.127  -0.152
120   Y         1.099   0.950   0.921   1.448   1.233   1.174   1.146   0.891   0.798
121   A         0.126   0.248   0.117   0.110   0.281   0.136  -0.047   0.135  -0.061
122   I         0.432   0.551   0.210   0.545   0.701   0.243   0.430   0.605   0.089
123   L        -0.455  -0.300  -0.472  -0.470  -0.203  -0.493  -0.524  -0.326  -0.516
124   F        -2.065  -2.029  -1.928  -1.600  -1.548  -1.392  -1.359  -1.320  -1.191
125   V        -0.777  -0.782  -0.930  -0.508  -0.562  -0.841  -0.644  -0.651  -0.780
126   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
127   E         1.099   0.950   0.921   1.070   0.857   0.845   1.146   0.891   0.798
128   V        -0.133  -0.032   0.002  -0.376  -0.182  -0.178  -0.405  -0.257  -0.230
129   K         1.099   1.196   0.962   1.067   1.229   0.893   1.146   1.299   0.876
130   E         1.799   1.855   1.964   1.685   1.744   1.945   1.981   2.073   2.259
131   L         1.799   1.855   1.964   1.581   1.667   1.839   1.981   2.073   2.259
132   S        -1.099  -1.118  -1.005  -0.825  -0.838  -0.678  -1.001  -1.002  -0.860
133   Q        -0.455  -0.506  -0.512  -0.199  -0.242  -0.276  -0.524  -0.570  -0.566
134   L        -0.133  -0.144  -0.063  -0.376  -0.390  -0.306  -0.405  -0.430  -0.328
135   K        -0.012  -0.087   0.019  -0.137  -0.174  -0.045  -0.286  -0.356  -0.223
136   D         1.099   1.100   0.942   1.244   1.255   1.053   1.146   1.146   0.839
137   L        -0.656  -0.691  -0.576  -0.771  -0.771  -0.595  -0.763  -0.779  -0.643
138   M         0.432   0.536   0.213   0.412   0.558   0.175   0.430   0.584   0.093
139   A        -0.455  -0.350  -0.495  -0.371  -0.226  -0.440  -0.524  -0.399  -0.550
140   W        -1.299  -1.333  -1.311  -1.299  -1.395  -1.267  -1.001  -1.026  -0.963
141   K         1.099   0.950   0.921   1.014   0.815   0.706   1.146   0.891   0.798
142   I         0.126   0.112   0.045   0.444   0.405   0.305  -0.047  -0.095  -0.180
143   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
144   N         1.099   1.183   0.959   1.442   1.568   1.271   1.146   1.280   0.871
145   V        -1.421  -1.310  -1.325  -1.257  -1.123  -1.093  -1.121  -1.015  -0.979
146   E         1.099   1.180   0.954   1.046   1.136   0.845   1.146   1.274   0.861
147   F         1.799   1.855   1.964   2.124   2.216   2.392   1.981   2.073   2.259
148   V         0.126   0.236   0.104   0.101   0.261   0.093  -0.047   0.121  -0.082
149   N        -0.777  -0.848  -0.904  -0.758  -0.858  -0.955  -0.644  -0.722  -0.753
150   G        -1.817  -1.805  -1.678  -1.582  -1.561  -1.374  -1.291  -1.266  -1.121
151   V        -0.067  -0.022  -0.017  -0.279  -0.223  -0.184  -0.356  -0.296  -0.272
152   I        -0.534  -0.510  -0.521  -0.716  -0.688  -0.650  -0.644  -0.604  -0.582
153   A        -0.656  -0.616  -0.572  -0.934  -0.895  -0.802  -0.763  -0.717  -0.641
154   D        -0.012   0.041   0.006  -0.075  -0.029  -0.078  -0.286  -0.230  -0.245
155   H        -0.978  -0.970  -0.963  -1.028  -0.984  -0.971  -0.882  -0.871  -0.822
156   I        -0.455  -0.305  -0.472  -0.404  -0.180  -0.405  -0.524  -0.329  -0.516
157   D        -0.196  -0.266  -0.426   0.133  -0.011  -0.284  -0.166  -0.262  -0.451
158   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
159   -        -0.677  -0.650  -0.597  -0.930  -0.841  -0.837  -0.768  -0.737  -0.660
160   V         0.432   0.322   0.154   0.707   0.558   0.303   0.430   0.260   0.003
161   P         0.432   0.252   0.139   0.684   0.428   0.232   0.430   0.164  -0.020
162   E        -0.196  -0.259  -0.415  -0.114  -0.217  -0.394  -0.166  -0.253  -0.437
163   K         1.099   0.950   0.921   1.042   0.857   0.771   1.146   0.891   0.798
164   I         0.126   0.034   0.051   0.246   0.147   0.134  -0.047  -0.160  -0.168
165   I        -0.978  -0.994  -0.979  -0.904  -0.876  -0.857  -0.882  -0.885  -0.834
166   K        -0.133  -0.129  -0.059  -0.304  -0.270  -0.173  -0.405  -0.405  -0.322
167   K         0.126   0.046   0.067  -0.075  -0.191  -0.208  -0.047  -0.142  -0.136
168   C         0.569   0.563   0.668   0.493   0.413   0.529   0.192   0.151   0.291
169   S        -0.455  -0.500  -0.498  -0.328  -0.367  -0.368  -0.524  -0.562  -0.552
170   P        -0.212  -0.180  -0.074  -0.354  -0.290  -0.143  -0.524  -0.479  -0.345
171   S        -1.743  -1.736  -1.665  -1.522  -1.506  -1.350  -1.240  -1.221  -1.112
172   V        -0.978  -0.996  -0.977  -1.060  -1.061  -1.071  -0.882  -0.886  -0.832
173   P         1.799   1.855   1.964   1.944   2.039   2.209   1.981   2.073   2.259
174   K        -0.534  -0.501  -0.526  -0.650  -0.597  -0.603  -0.644  -0.597  -0.588
175   E        -0.777  -0.784  -0.906  -0.823  -0.870  -1.053  -0.644  -0.654  -0.755
176   E         0.126   0.248   0.117   0.010   0.168   0.005  -0.047   0.135  -0.061
177   L         1.799   1.855   1.964   1.581   1.667   1.839   1.981   2.073   2.259
178   V         1.099   1.180   0.954   1.312   1.430   1.113   1.146   1.274   0.861
179   D        -0.978  -0.971  -0.961  -0.964  -1.007  -0.924  -0.882  -0.871  -0.820
180   L         0.432   0.252   0.139   0.332   0.072  -0.087   0.430   0.164  -0.020
181   Y         1.799   1.855   1.964   2.097   2.183   2.364   1.981   2.073   2.259
182   L         1.099   0.950   0.921   0.955   0.761   0.716   1.146   0.891   0.798
183   K        -0.455  -0.402  -0.497  -0.489  -0.396  -0.550  -0.524  -0.443  -0.545
184   E         1.799   1.855   1.964   1.685   1.744   1.945   1.981   2.073   2.259
185   I         1.099   0.950   0.921   1.202   0.982   0.895   1.146   0.891   0.798
186   A         1.099   0.950   0.921   1.144   0.932   0.890   1.146   0.891   0.798
187   K         0.754   0.790   0.750   0.733   0.790   0.641   0.549   0.599   0.460
188   T        -0.012   0.009   0.014  -0.047   0.016   0.020  -0.286  -0.240  -0.227
189   Y         1.799   1.855   1.964   2.097   2.183   2.364   1.981   2.073   2.259
190   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
191   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
192   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
193   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
194   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
195   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
196   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
197   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
198   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
199   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
200   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
201   D        -0.978  -0.905  -0.950  -0.849  -0.740  -0.794  -0.882  -0.792  -0.807
202   V         0.126   0.032   0.047   0.162   0.029   0.000  -0.047  -0.163  -0.171
203   P         1.099   1.100   0.942   1.328   1.351   1.131   1.146   1.146   0.839
204   Y        -0.455  -0.562  -0.525  -0.048  -0.194  -0.121  -0.524  -0.632  -0.584
205   S         1.099   1.100   0.942   1.286   1.298   1.078   1.146   1.146   0.839
206   K        -0.978  -1.012  -0.972  -1.055  -1.133  -1.157  -0.882  -0.908  -0.829
207   L        -0.196  -0.334  -0.439  -0.316  -0.551  -0.701  -0.166  -0.344  -0.468
208   E        -0.978  -0.990  -0.979  -1.128  -1.153  -1.082  -0.882  -0.882  -0.833
209   N        -0.574  -0.493  -0.515  -0.685  -0.552  -0.572  -0.668  -0.557  -0.571
210   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
211   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
212   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
213   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
214   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
215   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
216   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
217   S        -0.978  -1.028  -0.988  -1.015  -1.089  -0.981  -0.882  -0.918  -0.843
218   L        -1.743  -1.742  -1.645  -1.609  -1.528  -1.440  -1.240  -1.225  -1.099
219   S        -1.099  -1.032  -1.003  -1.349  -1.297  -1.196  -1.001  -0.927  -0.857
220   S        -1.299  -1.319  -1.309  -1.053  -1.079  -1.079  -1.001  -1.013  -0.962
221   S        -0.978  -1.045  -0.965  -0.949  -1.132  -0.994  -0.882  -0.932  -0.820
222   S        -1.421  -1.353  -1.337  -1.426  -1.364  -1.298  -1.121  -1.050  -0.988
223   S        -0.978  -0.908  -0.932  -0.831  -0.720  -0.765  -0.882  -0.797  -0.790
224   N        -1.421  -1.328  -1.333  -1.343  -1.218  -1.207  -1.121  -1.033  -0.985
225   I        -0.777  -0.847  -0.919  -0.668  -0.814  -0.946  -0.644  -0.721  -0.768
226   S        -1.099  -1.064  -1.000  -0.924  -0.855  -0.734  -1.001  -0.957  -0.856
227   S        -1.099  -1.121  -1.012  -1.328  -1.352  -1.199  -1.001  -1.004  -0.865
228   D        -0.455  -0.422  -0.514  -0.550  -0.585  -0.694  -0.524  -0.512  -0.574
229   F        -0.455  -0.495  -0.526  -0.447  -0.492  -0.519  -0.524  -0.557  -0.581
230   S        -0.656  -0.663  -0.587  -0.775  -0.794  -0.683  -0.763  -0.761  -0.655
231   D        -1.421  -1.450  -1.351  -1.379  -1.404  -1.297  -1.121  -1.128  -0.999
232   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
233   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
234   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
235   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
236   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
237   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
238   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
239   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
240   P        -0.574  -0.507  -0.538  -0.630  -0.525  -0.591  -0.668  -0.583  -0.595
241   S        -0.067  -0.021  -0.011  -0.173  -0.110  -0.054  -0.356  -0.296  -0.264
242   G        -0.574  -0.547  -0.540  -0.593  -0.528  -0.545  -0.668  -0.623  -0.598
243   D        -0.978  -0.918  -0.964  -0.794  -0.714  -0.804  -0.882  -0.823  -0.822
244   I        -1.421  -1.332  -1.331  -1.395  -1.303  -1.259  -1.121  -1.035  -0.984
245   E        -0.978  -0.907  -0.943  -1.204  -1.082  -1.133  -0.882  -0.796  -0.798
246   D        -0.978  -0.901  -0.939  -0.991  -0.909  -0.889  -0.882  -0.791  -0.797
247   N        -1.449  -1.412  -1.363  -1.453  -1.436  -1.303  -1.135  -1.095  -1.007
248   D        -1.081  -1.001  -0.991  -1.116  -0.946  -0.993  -0.979  -0.890  -0.845
249   E        -1.081  -1.073  -1.009  -1.296  -1.270  -1.181  -0.979  -0.961  -0.862
250   E        -0.942  -0.939  -0.945  -0.951  -0.969  -0.938  -0.824  -0.820  -0.796
251   K        -0.455  -0.382  -0.493  -0.666  -0.554  -0.709  -0.524  -0.422  -0.542
252   P         1.799   1.855   1.964   1.942   2.038   2.206   1.981   2.073   2.259
253   I        -0.067  -0.036  -0.027  -0.419  -0.374  -0.346  -0.356  -0.312  -0.285
254   L         0.033  -0.025  -0.023  -0.283  -0.387  -0.423  -0.157  -0.246  -0.267
255   A         1.799   1.855   1.964   1.793   1.880   2.055   1.981   2.073   2.259
256   L        -0.677  -0.692  -0.608  -0.852  -0.905  -0.800  -0.768  -0.780  -0.673
257   D         0.033   0.068   0.024   0.050   0.096   0.021  -0.157  -0.107  -0.196
258   N        -0.510  -0.588  -0.568  -0.366  -0.518  -0.514  -0.564  -0.659  -0.627
259   D        -0.510  -0.439  -0.509  -0.450  -0.360  -0.466  -0.564  -0.470  -0.555
260   D         0.187   0.237   0.113   0.031   0.083  -0.113   0.072   0.146  -0.059
261   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
262   D        -0.677  -0.663  -0.597  -0.730  -0.715  -0.595  -0.768  -0.749  -0.660
263   N        -1.101  -1.013  -0.988  -0.855  -0.718  -0.684  -0.988  -0.888  -0.839
264   A        -0.510  -0.455  -0.514  -0.377  -0.291  -0.450  -0.564  -0.489  -0.561
265   D        -0.510  -0.588  -0.568  -0.495  -0.640  -0.630  -0.564  -0.659  -0.627
266   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
267   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
268   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
269   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
270   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
271   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
272   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
273   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
274   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
275   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
276   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
277   A        -1.101  -1.056  -1.019  -1.213  -1.193  -1.135  -0.988  -0.938  -0.868
278   K        -0.081  -0.037  -0.020  -0.496  -0.432  -0.433  -0.352  -0.313  -0.275
279   H        -0.081  -0.151  -0.046   0.045  -0.075   0.077  -0.352  -0.440  -0.307
280   P         0.961   0.846   0.865   1.118   0.944   0.952   0.921   0.703   0.691
281   I         0.187   0.062   0.058   0.200  -0.008  -0.080   0.072  -0.118  -0.144
282   T        -1.101  -1.025  -0.991  -1.129  -0.989  -0.953  -0.988  -0.900  -0.842
283   V        -0.081  -0.147  -0.026  -0.168  -0.260  -0.087  -0.352  -0.434  -0.281
284   K        -1.101  -1.111  -1.025  -1.230  -1.243  -1.100  -0.988  -0.989  -0.875
285   K        -0.081  -0.151  -0.046  -0.398  -0.512  -0.368  -0.352  -0.440  -0.307
286   P         1.799   1.855   1.964   1.941   2.031   2.206   1.981   2.073   2.259
287   R        -0.510  -0.588  -0.568  -0.398  -0.523  -0.522  -0.564  -0.659  -0.627
288   Q        -0.672  -0.674  -0.595  -0.656  -0.641  -0.558  -0.776  -0.770  -0.661
289   N        -0.455  -0.402  -0.497  -0.207  -0.122  -0.263  -0.524  -0.443  -0.545
290   S        -0.012  -0.025   0.006   0.035   0.032   0.104  -0.286  -0.300  -0.244
291   E        -0.656  -0.624  -0.578  -0.887  -0.864  -0.747  -0.763  -0.731  -0.647
292   N        -0.212  -0.160  -0.060  -0.272  -0.184  -0.040  -0.524  -0.455  -0.326
293   I        -0.978  -1.005  -0.962  -1.115  -1.124  -1.038  -0.882  -0.902  -0.820
294   K        -0.777  -0.851  -0.909  -0.677  -0.784  -0.839  -0.644  -0.725  -0.759
295   N        -0.656  -0.609  -0.582  -0.589  -0.538  -0.466  -0.763  -0.714  -0.651
296   E        -0.196  -0.309  -0.433  -0.208  -0.407  -0.588  -0.166  -0.316  -0.460
297   L         0.432   0.485   0.203   0.374   0.450   0.092   0.430   0.508   0.078
298   K        -0.196  -0.334  -0.439  -0.159  -0.319  -0.516  -0.166  -0.344  -0.468
299   I        -0.978  -1.006  -0.991  -1.039  -1.099  -1.050  -0.882  -0.904  -0.846
300   P        -0.777  -0.852  -0.921  -0.467  -0.593  -0.693  -0.644  -0.726  -0.771
301   K        -0.978  -1.043  -0.996  -0.924  -0.961  -0.849  -0.882  -0.930  -0.849
302   D        -1.099  -1.110  -1.019  -0.995  -0.972  -0.857  -1.001  -0.996  -0.871
303   I        -0.510  -0.555  -0.531  -0.512  -0.624  -0.588  -0.564  -0.622  -0.582
304   K        -0.574  -0.545  -0.543  -0.809  -0.737  -0.765  -0.668  -0.642  -0.606
305   K        -1.449  -1.458  -1.369  -1.444  -1.418  -1.297  -1.135  -1.131  -1.011
306   E        -0.942  -0.951  -0.947  -0.902  -0.914  -0.965  -0.824  -0.831  -0.797
307   V        -0.574  -0.604  -0.562  -0.533  -0.571  -0.529  -0.668  -0.697  -0.627
308   I        -0.677  -0.630  -0.568  -0.580  -0.487  -0.426  -0.768  -0.706  -0.626
309   E        -0.677  -0.645  -0.583  -1.009  -1.023  -0.884  -0.768  -0.727  -0.644
310   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
311   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
312   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
313   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
314   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
315   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
316   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
317   K         0.869   0.988   0.835   0.689   0.896   0.620   0.759   0.958   0.633
318   T        -0.161  -0.084  -0.058  -0.274  -0.179  -0.124  -0.462  -0.357  -0.324
319   T        -1.192  -1.158  -1.048  -1.223  -1.206  -1.010  -1.073  -1.030  -0.896
320   K         0.033  -0.062  -0.023  -0.208  -0.344  -0.318  -0.157  -0.302  -0.267
321   R        -0.677  -0.543  -0.587  -0.733  -0.531  -0.594  -0.768  -0.598  -0.648
322   K         0.869   0.832   0.816   0.725   0.700   0.646   0.759   0.678   0.594
323   T        -0.677  -0.636  -0.585  -0.665  -0.603  -0.516  -0.768  -0.716  -0.647
324   K        -1.449  -1.384  -1.341  -1.335  -1.196  -1.195  -1.135  -1.065  -0.988
325   K        -1.421  -1.440  -1.339  -1.427  -1.378  -1.271  -1.121  -1.122  -0.990
326   E        -1.743  -1.742  -1.662  -1.752  -1.739  -1.612  -1.240  -1.226  -1.111
327   Q        -1.081  -1.104  -0.996  -1.039  -1.046  -0.895  -0.979  -0.988  -0.851
328   E        -0.067  -0.043   0.004  -0.442  -0.392  -0.298  -0.356  -0.316  -0.244
329   N        -1.449  -1.438  -1.354  -1.405  -1.431  -1.271  -1.135  -1.115  -0.999
330   D        -0.455  -0.435  -0.515  -0.382  -0.386  -0.458  -0.524  -0.525  -0.576
331   E        -0.212  -0.207  -0.090  -0.564  -0.573  -0.376  -0.524  -0.517  -0.366
332   L        -0.012   0.014   0.019  -0.092   0.003  -0.005  -0.286  -0.231  -0.218
333   D         0.754   0.708   0.723   0.644   0.517   0.492   0.549   0.441   0.406
334   E        -0.012   0.071   0.040  -0.354  -0.252  -0.255  -0.286  -0.165  -0.197
335   L         1.799   1.855   1.964   1.581   1.667   1.839   1.981   2.073   2.259
336   K        -0.455  -0.433  -0.520  -0.599  -0.596  -0.681  -0.524  -0.523  -0.581
337   K         0.569   0.579   0.681   0.163   0.175   0.308   0.192   0.185   0.319
338   R         1.799   1.855   1.964   1.944   2.026   2.209   1.981   2.073   2.259
339   F         0.754   0.701   0.719   0.875   0.743   0.673   0.549   0.429   0.397
340   D        -0.012   0.074   0.034  -0.256  -0.141  -0.188  -0.286  -0.176  -0.201
341   A         1.099   0.950   0.921   1.153   0.945   0.912   1.146   0.891   0.798
342   L         1.799   1.855   1.964   1.581   1.667   1.839   1.981   2.073   2.259
343   R         0.569   0.644   0.700   0.255   0.396   0.449   0.192   0.316   0.358
344   R        -0.677  -0.711  -0.611  -0.415  -0.446  -0.320  -0.768  -0.803  -0.677
345   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
346   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
347   K        -0.455  -0.477  -0.490  -0.624  -0.668  -0.696  -0.524  -0.538  -0.537
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P53843
Output conservation file - output/P53843
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
