1     M         1.353   1.357   1.436   1.571   1.577   1.694   1.473   1.479   1.602
2     L         1.353   1.357   1.436   1.217   1.224   1.353   1.473   1.479   1.602
3     H        -0.973  -0.984  -1.097  -0.652  -0.678  -0.886  -0.840  -0.852  -0.941
4     L         0.409   0.449   0.404   0.198   0.264   0.175   0.212   0.282   0.155
5     Q        -0.863  -0.874  -0.789  -0.968  -0.986  -0.856  -0.945  -0.953  -0.826
6     P        -0.754  -0.714  -0.768  -0.636  -0.588  -0.627  -0.840  -0.801  -0.806
7     Q        -0.754  -0.748  -0.751  -0.697  -0.689  -0.671  -0.840  -0.833  -0.788
8     N         1.353   1.357   1.436   1.454   1.464   1.581   1.473   1.479   1.602
9     L         0.119   0.049  -0.178   0.092  -0.001  -0.350   0.107   0.009  -0.332
10    L         0.721   0.675   0.500   0.653   0.595   0.342   0.737   0.664   0.336
11    I         0.119   0.120  -0.161   0.207   0.210  -0.243   0.107   0.108  -0.307
12    Q         0.119   0.100  -0.162   0.303   0.278  -0.114   0.107   0.079  -0.308
13    K        -0.973  -0.984  -1.097  -0.828  -0.848  -1.038  -0.840  -0.852  -0.941
14    T        -0.158  -0.199  -0.260  -0.200  -0.264  -0.403  -0.314  -0.366  -0.457
15    L         1.353   1.357   1.436   1.217   1.224   1.353   1.473   1.479   1.602
16    N        -0.448  -0.402  -0.667  -0.265  -0.200  -0.606  -0.419  -0.361  -0.681
17    E         0.721   0.761   0.511   0.759   0.809   0.459   0.737   0.798   0.356
18    A         0.243   0.248   0.328   0.034   0.038   0.158  -0.104  -0.096   0.004
19    I        -0.392  -0.401  -0.328  -0.685  -0.701  -0.589  -0.629  -0.644  -0.549
20    E        -1.264  -1.285  -1.163  -1.354  -1.382  -1.194  -1.155  -1.167  -1.006
21    A         0.207   0.215   0.314   0.062   0.072   0.222  -0.174  -0.160  -0.024
22    L        -0.882  -0.894  -0.796  -0.986  -1.010  -0.884  -0.949  -0.961  -0.831
23    R        -0.882  -0.869  -0.814  -0.830  -0.808  -0.755  -0.949  -0.932  -0.850
24    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
25    K        -1.555  -1.572  -1.463  -1.475  -1.491  -1.323  -1.260  -1.270  -1.119
26    G        -1.154  -1.150  -1.145  -1.013  -1.012  -1.036  -1.050  -1.044  -0.990
27    S        -0.682  -0.674  -0.720  -0.632  -0.611  -0.674  -0.734  -0.717  -0.750
28    P         0.409   0.449   0.404   0.393   0.462   0.336   0.212   0.282   0.155
29    L        -0.682  -0.713  -0.741  -0.838  -0.872  -0.919  -0.734  -0.759  -0.770
30    T        -0.754  -0.753  -0.767  -0.766  -0.763  -0.735  -0.840  -0.837  -0.804
31    M        -0.282  -0.284  -0.289  -0.503  -0.507  -0.448  -0.524  -0.530  -0.503
32    D         1.353   1.357   1.436   1.352   1.360   1.483   1.473   1.479   1.602
33    R         0.243   0.232   0.320   0.051   0.028   0.161  -0.104  -0.126  -0.012
34    I        -0.158  -0.192  -0.264  -0.198  -0.251  -0.378  -0.314  -0.361  -0.464
35    V         0.409   0.414   0.390   0.312   0.318   0.252   0.212   0.218   0.127
36    S         0.721   0.675   0.500   0.781   0.725   0.468   0.737   0.664   0.336
37    D         1.353   1.357   1.436   1.352   1.360   1.483   1.473   1.479   1.602
38    F         1.353   1.357   1.436   1.354   1.360   1.484   1.473   1.479   1.602
39    D         1.353   1.357   1.436   1.352   1.360   1.483   1.473   1.479   1.602
40    Y        -0.863  -0.848  -0.799  -0.804  -0.778  -0.699  -0.945  -0.930  -0.837
41    T         0.243   0.232   0.320   0.043   0.017   0.143  -0.104  -0.126  -0.012
42    T         0.721   0.695   0.504   0.819   0.785   0.499   0.737   0.697   0.343
43    Y        -0.158  -0.157  -0.251  -0.180  -0.174  -0.345  -0.314  -0.305  -0.447
44    H         1.353   1.357   1.436   1.521   1.527   1.646   1.473   1.479   1.602
45    I         0.119   0.171  -0.149   0.207   0.278  -0.221   0.107   0.179  -0.289
46    S         0.721   0.700   0.500   0.781   0.758   0.467   0.737   0.704   0.336
47    N         0.190   0.194   0.305   0.013   0.020   0.193  -0.209  -0.202  -0.041
48    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
49    T        -0.490  -0.482  -0.350  -0.831  -0.812  -0.603  -0.770  -0.757  -0.580
50    A         0.119   0.101  -0.168   0.370   0.348  -0.044   0.107   0.082  -0.317
51    E        -1.154  -1.122  -1.119  -1.132  -1.082  -1.063  -1.050  -1.013  -0.967
52    D        -0.863  -0.867  -0.786  -0.963  -0.967  -0.843  -0.945  -0.944  -0.824
53    K         0.721   0.761   0.511   0.783   0.836   0.480   0.737   0.798   0.356
54    S        -0.754  -0.714  -0.768  -0.795  -0.745  -0.780  -0.840  -0.801  -0.806
55    I        -1.264  -1.257  -1.171  -1.401  -1.378  -1.235  -1.155  -1.146  -1.012
56    L         0.190   0.194   0.305  -0.184  -0.175   0.004  -0.209  -0.202  -0.041
57    L         0.721   0.747   0.509   0.685   0.719   0.429   0.737   0.778   0.352
58    L        -0.463  -0.452  -0.338  -0.777  -0.758  -0.586  -0.734  -0.720  -0.565
59    S         1.353   1.357   1.436   1.340   1.349   1.472   1.473   1.479   1.602
60    V        -0.754  -0.749  -0.751  -0.903  -0.902  -0.846  -0.840  -0.832  -0.789
61    K        -1.264  -1.268  -1.162  -1.266  -1.272  -1.109  -1.155  -1.154  -1.005
62    T        -0.863  -0.875  -0.800  -0.983  -0.982  -0.856  -0.945  -0.950  -0.837
63    K         0.409   0.411   0.368   0.324   0.327   0.220   0.212   0.212   0.084
64    A         0.243   0.248   0.328   0.267   0.273   0.371  -0.104  -0.096   0.004
65    W        -0.682  -0.733  -0.751  -0.409  -0.486  -0.548  -0.734  -0.789  -0.784
66    V        -0.682  -0.661  -0.733  -0.606  -0.581  -0.695  -0.734  -0.714  -0.765
67    S        -0.282  -0.313  -0.292  -0.453  -0.491  -0.453  -0.524  -0.556  -0.507
68    V        -0.448  -0.442  -0.692  -0.400  -0.386  -0.731  -0.419  -0.411  -0.711
69    S        -0.448  -0.442  -0.692  -0.344  -0.331  -0.742  -0.419  -0.411  -0.711
70    E        -1.264  -1.259  -1.161  -1.282  -1.274  -1.119  -1.155  -1.148  -1.005
71    C        -1.154  -1.129  -1.127  -0.847  -0.816  -0.800  -1.050  -1.023  -0.975
72    Q         0.119   0.148  -0.151   0.402   0.441  -0.012   0.107   0.148  -0.293
73    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
74    D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
75    G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
76    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
77    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
78    T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
79    L        -0.863  -0.875  -0.800  -1.092  -1.104  -0.969  -0.945  -0.950  -0.837
80    L        -1.154  -1.136  -1.128  -1.286  -1.258  -1.229  -1.050  -1.031  -0.975
81    K        -1.445  -1.464  -1.424  -1.258  -1.288  -1.235  -1.155  -1.171  -1.087
82    F        -1.154  -1.168  -1.152  -1.141  -1.166  -1.166  -1.050  -1.057  -0.995
83    L         1.353   1.357   1.436   1.217   1.224   1.353   1.473   1.479   1.602
84    A        -1.555  -1.545  -1.458  -1.379  -1.371  -1.243  -1.260  -1.251  -1.116
85    D        -1.555  -1.553  -1.456  -1.424  -1.427  -1.261  -1.260  -1.256  -1.114
86    H        -0.682  -0.715  -0.747  -0.680  -0.728  -0.763  -0.734  -0.770  -0.779
87    Y         0.721   0.700   0.500   0.899   0.874   0.570   0.737   0.704   0.336
88    S        -1.264  -1.258  -1.155  -1.214  -1.205  -1.053  -1.155  -1.148  -1.000
89    S        -1.845  -1.853  -1.719  -1.649  -1.669  -1.492  -1.365  -1.368  -1.203
90    L        -1.154  -1.140  -1.125  -1.139  -1.125  -1.122  -1.050  -1.037  -0.973
91    G        -1.348  -1.342  -1.189  -1.236  -1.225  -1.009  -1.218  -1.210  -1.027
92    G         0.513   0.517   0.409   0.668   0.674   0.459   0.397   0.402   0.165
93    V        -0.242  -0.263  -0.286  -0.311  -0.347  -0.420  -0.411  -0.442  -0.489
94    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
95    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
96    T        -0.882  -0.868  -0.792  -0.994  -0.969  -0.872  -0.949  -0.932  -0.826
97    I        -0.242  -0.209  -0.289  -0.463  -0.412  -0.551  -0.411  -0.364  -0.493
98    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
99    P        -1.555  -1.521  -1.455  -1.549  -1.499  -1.400  -1.260  -1.232  -1.114
100   S        -1.845  -1.854  -1.718  -1.612  -1.623  -1.447  -1.365  -1.369  -1.201
101   E        -1.154  -1.152  -1.124  -1.149  -1.140  -1.088  -1.050  -1.042  -0.969
102   V        -0.754  -0.742  -0.759  -0.781  -0.760  -0.779  -0.840  -0.826  -0.797
103   E         1.353   1.357   1.436   1.323   1.328   1.455   1.473   1.479   1.602
104   P        -1.154  -1.153  -1.129  -0.984  -0.988  -0.946  -1.050  -1.051  -0.976
105   G         0.721   0.761   0.511   0.965   1.015   0.668   0.737   0.798   0.356
106   Y         0.721   0.751   0.510   0.899   0.940   0.587   0.737   0.784   0.353
107   D         0.409   0.404   0.368   0.362   0.356   0.276   0.212   0.200   0.085
108   Y        -0.282  -0.274  -0.286  -0.350  -0.353  -0.356  -0.524  -0.523  -0.502
109   T         0.243   0.248   0.328   0.031   0.039   0.155  -0.104  -0.096   0.004
110   L        -0.282  -0.265  -0.279  -0.503  -0.489  -0.438  -0.524  -0.513  -0.494
111   Q        -0.863  -0.866  -0.783  -1.023  -1.025  -0.901  -0.945  -0.942  -0.820
112   I        -0.463  -0.468  -0.353  -0.805  -0.807  -0.626  -0.734  -0.739  -0.584
113   T         0.119   0.145  -0.156   0.253   0.290  -0.139   0.107   0.144  -0.299
114   L         0.119   0.171  -0.149   0.101   0.171  -0.284   0.107   0.179  -0.289
115   A        -1.445  -1.456  -1.438  -1.273  -1.297  -1.271  -1.155  -1.164  -1.099
116   E        -1.445  -1.414  -1.415  -1.258  -1.208  -1.246  -1.155  -1.125  -1.080
117   L        -0.448  -0.425  -0.664  -0.412  -0.382  -0.710  -0.419  -0.390  -0.677
118   V        -1.264  -1.246  -1.161  -1.237  -1.206  -1.077  -1.155  -1.138  -1.004
119   Q        -1.445  -1.375  -1.421  -1.299  -1.192  -1.295  -1.155  -1.088  -1.085
120   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
121   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
122   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
123   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
124   -        -0.242  -0.290  -0.300  -0.311  -0.392  -0.438  -0.411  -0.482  -0.509
125   -        -0.882  -0.870  -0.794  -0.953  -0.933  -0.826  -0.949  -0.933  -0.829
126   -         0.513   0.535   0.412   0.451   0.482   0.265   0.397   0.432   0.169
127   -        -0.882  -0.902  -0.814  -0.972  -1.016  -0.882  -0.949  -0.970  -0.850
128   -         0.224   0.228   0.316  -0.045  -0.037   0.092  -0.142  -0.136  -0.019
129   -        -0.882  -0.874  -0.806  -1.040  -1.030  -0.943  -0.949  -0.939  -0.841
130   E        -0.282  -0.291  -0.278  -0.402  -0.408  -0.378  -0.524  -0.528  -0.491
131   S        -0.158  -0.143  -0.259  -0.328  -0.311  -0.479  -0.314  -0.299  -0.456
132   I        -0.158  -0.199  -0.260  -0.199  -0.258  -0.371  -0.314  -0.366  -0.457
133   L        -1.555  -1.534  -1.457  -1.419  -1.375  -1.304  -1.260  -1.241  -1.115
134   Q        -1.555  -1.535  -1.464  -1.518  -1.489  -1.396  -1.260  -1.243  -1.120
135   L        -0.754  -0.747  -0.761  -0.870  -0.858  -0.816  -0.840  -0.830  -0.798
136   S         0.409   0.409   0.383   0.327   0.327   0.258   0.212   0.209   0.114
137   V        -1.445  -1.418  -1.423  -1.370  -1.322  -1.320  -1.155  -1.129  -1.087
138   L         0.721   0.700   0.500   0.653   0.628   0.341   0.737   0.704   0.336
139   K         1.353   1.357   1.436   1.348   1.356   1.479   1.473   1.479   1.602
140   T        -0.158  -0.161  -0.254  -0.190  -0.191  -0.347  -0.314  -0.312  -0.447
141   I        -0.682  -0.651  -0.739  -0.631  -0.585  -0.721  -0.734  -0.699  -0.770
142   I        -1.154  -1.116  -1.124  -1.079  -1.036  -1.010  -1.050  -1.013  -0.972
143   L        -0.282  -0.265  -0.278  -0.337  -0.320  -0.333  -0.524  -0.507  -0.491
144   S         0.243   0.248   0.328   0.042   0.046   0.161  -0.104  -0.096   0.004
145   F        -0.158  -0.161  -0.254  -0.151  -0.153  -0.297  -0.314  -0.312  -0.447
146   P         1.353   1.357   1.436   1.461   1.467   1.588   1.473   1.479   1.602
147   F         1.353   1.357   1.436   1.354   1.360   1.484   1.473   1.479   1.602
148   E        -0.158  -0.186  -0.256  -0.140  -0.180  -0.266  -0.314  -0.353  -0.455
149   L        -0.682  -0.706  -0.735  -0.711  -0.755  -0.814  -0.734  -0.762  -0.765
150   A         1.353   1.357   1.436   1.380   1.382   1.510   1.473   1.479   1.602
151   I         0.119   0.097  -0.160   0.251   0.224  -0.151   0.107   0.076  -0.305
152   S        -1.845  -1.850  -1.715  -1.647  -1.648  -1.459  -1.365  -1.366  -1.199
153   K        -0.863  -0.860  -0.777  -1.003  -0.993  -0.863  -0.945  -0.936  -0.814
154   F        -1.154  -1.195  -1.138  -1.039  -1.090  -1.000  -1.050  -1.081  -0.982
155   I        -1.445  -1.482  -1.447  -1.217  -1.272  -1.214  -1.155  -1.187  -1.106
156   E        -0.392  -0.389  -0.335  -0.554  -0.556  -0.478  -0.629  -0.626  -0.560
157   L         1.353   1.357   1.436   1.217   1.224   1.353   1.473   1.479   1.602
158   S        -0.682  -0.691  -0.743  -0.678  -0.695  -0.763  -0.734  -0.746  -0.776
159   Q        -1.154  -1.153  -1.137  -1.126  -1.129  -1.091  -1.050  -1.049  -0.982
160   Q        -1.247  -1.214  -1.154  -1.394  -1.356  -1.240  -1.136  -1.105  -0.997
161   Q        -0.863  -0.853  -0.793  -0.864  -0.846  -0.744  -0.945  -0.926  -0.830
162   P        -1.154  -1.201  -1.148  -1.091  -1.165  -1.098  -1.050  -1.089  -0.991
163   A        -1.264  -1.235  -1.162  -1.298  -1.263  -1.133  -1.155  -1.130  -1.005
164   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
165   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
166   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
167   A        -0.882  -0.849  -0.791  -0.981  -0.926  -0.868  -0.949  -0.911  -0.826
168   E        -0.882  -0.925  -0.814  -0.824  -0.904  -0.736  -0.949  -0.997  -0.850
169   I        -0.732  -0.773  -0.766  -0.720  -0.804  -0.823  -0.770  -0.824  -0.798
170   T        -1.266  -1.284  -1.179  -1.182  -1.210  -1.078  -1.143  -1.161  -1.018
171   G        -1.266  -1.265  -1.162  -1.299  -1.282  -1.161  -1.143  -1.144  -1.003
172   G        -0.732  -0.773  -0.766  -0.677  -0.736  -0.714  -0.770  -0.824  -0.798
173   E        -0.682  -0.733  -0.751  -0.651  -0.721  -0.718  -0.734  -0.789  -0.784
174   V        -1.264  -1.266  -1.170  -1.275  -1.285  -1.129  -1.155  -1.153  -1.011
175   A        -0.973  -1.002  -1.106  -0.791  -0.841  -1.042  -0.840  -0.870  -0.950
176   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
177   A        -1.247  -1.259  -1.157  -1.305  -1.323  -1.160  -1.136  -1.142  -1.000
178   N        -1.845  -1.858  -1.730  -1.841  -1.855  -1.654  -1.365  -1.371  -1.210
179   G        -1.555  -1.549  -1.446  -1.498  -1.490  -1.331  -1.260  -1.253  -1.108
180   D        -1.264  -1.277  -1.158  -1.245  -1.258  -1.081  -1.155  -1.161  -1.001
181   N        -1.264  -1.277  -1.158  -1.203  -1.214  -1.025  -1.155  -1.161  -1.001
182   T        -1.445  -1.403  -1.441  -1.276  -1.221  -1.270  -1.155  -1.115  -1.102
183   L        -0.158  -0.196  -0.259  -0.263  -0.331  -0.454  -0.314  -0.370  -0.459
184   F        -1.445  -1.406  -1.417  -1.136  -1.072  -1.156  -1.155  -1.117  -1.082
185   T        -0.463  -0.450  -0.352  -0.681  -0.664  -0.511  -0.734  -0.717  -0.583
186   I         1.353   1.357   1.436   1.354   1.360   1.484   1.473   1.479   1.602
187   K        -0.282  -0.260  -0.286  -0.317  -0.290  -0.290  -0.524  -0.505  -0.500
188   Y         1.353   1.357   1.436   1.463   1.471   1.590   1.473   1.479   1.602
189   R         1.353   1.357   1.436   1.348   1.353   1.479   1.473   1.479   1.602
190   D        -0.158  -0.149  -0.233  -0.142  -0.122  -0.257  -0.314  -0.292  -0.416
191   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
192   E         0.190   0.195   0.306  -0.107  -0.099   0.079  -0.209  -0.200  -0.039
193   E         1.353   1.357   1.436   1.323   1.328   1.455   1.473   1.479   1.602
194   N        -1.154  -1.167  -1.148  -0.995  -1.008  -0.975  -1.050  -1.056  -0.992
195   I         1.353   1.357   1.436   1.354   1.360   1.484   1.473   1.479   1.602
196   F        -0.158  -0.182  -0.242  -0.097  -0.124  -0.250  -0.314  -0.339  -0.429
197   I        -0.463  -0.464  -0.349  -0.777  -0.781  -0.610  -0.734  -0.735  -0.579
198   K         0.119   0.097  -0.164   0.276   0.254  -0.103   0.107   0.075  -0.312
199   P         0.409   0.411   0.360   0.444   0.444   0.316   0.212   0.213   0.068
200   S         0.119   0.101  -0.161   0.219   0.194  -0.204   0.107   0.080  -0.307
201   N        -1.154  -1.136  -1.138  -1.012  -0.986  -0.974  -1.050  -1.036  -0.983
202   D         1.353   1.357   1.436   1.352   1.360   1.483   1.473   1.479   1.602
203   R         1.353   1.357   1.436   1.348   1.353   1.479   1.473   1.479   1.602
204   V         0.721   0.700   0.500   0.769   0.743   0.450   0.737   0.704   0.336
205   T         1.353   1.357   1.436   1.385   1.391   1.515   1.473   1.479   1.602
206   I         0.721   0.727   0.506   0.769   0.778   0.461   0.737   0.746   0.348
207   I         0.721   0.675   0.500   0.787   0.727   0.463   0.737   0.664   0.336
208   F         1.353   1.357   1.436   1.354   1.360   1.484   1.473   1.479   1.602
209   E         0.243   0.248   0.328  -0.002   0.006   0.119  -0.104  -0.096   0.004
210   T         1.353   1.357   1.436   1.385   1.391   1.515   1.473   1.479   1.602
211   I         0.119   0.100  -0.162   0.228   0.202  -0.201   0.107   0.079  -0.308
212   F         1.353   1.357   1.436   1.354   1.360   1.484   1.473   1.479   1.602
213   Q        -0.392  -0.393  -0.329  -0.520  -0.528  -0.452  -0.629  -0.633  -0.551
214   D         0.409   0.370   0.369   0.320   0.250   0.214   0.212   0.137   0.087
215   E         1.353   1.357   1.436   1.323   1.328   1.455   1.473   1.479   1.602
216   T         1.353   1.357   1.436   1.385   1.391   1.515   1.473   1.479   1.602
217   D         1.353   1.357   1.436   1.352   1.360   1.483   1.473   1.479   1.602
218   K         0.243   0.232   0.320   0.017  -0.005   0.123  -0.104  -0.126  -0.012
219   I         0.409   0.383   0.353   0.325   0.278   0.188   0.212   0.162   0.055
220   F         0.721   0.751   0.510   0.770   0.811   0.442   0.737   0.784   0.353
221   G         1.353   1.357   1.436   1.515   1.521   1.640   1.473   1.479   1.602
222   K         1.353   1.357   1.436   1.348   1.356   1.479   1.473   1.479   1.602
223   V         1.353   1.357   1.436   1.333   1.339   1.465   1.473   1.479   1.602
224   F         1.353   1.357   1.436   1.354   1.360   1.484   1.473   1.479   1.602
225   L         0.721   0.695   0.504   0.653   0.622   0.348   0.737   0.697   0.343
226   Q         1.353   1.357   1.436   1.411   1.416   1.540   1.473   1.479   1.602
227   E         1.353   1.357   1.436   1.323   1.328   1.455   1.473   1.479   1.602
228   F         1.353   1.357   1.436   1.354   1.360   1.484   1.473   1.479   1.602
229   V         1.353   1.357   1.436   1.333   1.339   1.465   1.473   1.479   1.602
230   D         1.353   1.357   1.436   1.352   1.360   1.483   1.473   1.479   1.602
231   A         1.353   1.357   1.436   1.380   1.382   1.510   1.473   1.479   1.602
232   R         1.353   1.357   1.436   1.348   1.353   1.479   1.473   1.479   1.602
233   K         0.243   0.232   0.320   0.017  -0.005   0.123  -0.104  -0.126  -0.012
234   R         1.353   1.357   1.436   1.348   1.353   1.479   1.473   1.479   1.602
235   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
236   R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
237   Q        -0.754  -0.732  -0.761  -0.780  -0.755  -0.746  -0.840  -0.817  -0.798
238   I         0.409   0.449   0.404   0.325   0.391   0.289   0.212   0.282   0.155
239   Q         1.353   1.357   1.436   1.411   1.416   1.540   1.473   1.479   1.602
240   S        -0.463  -0.464  -0.353  -0.626  -0.625  -0.457  -0.734  -0.735  -0.584
241   A         1.353   1.357   1.436   1.380   1.382   1.510   1.473   1.479   1.602
242   P         1.353   1.357   1.436   1.461   1.467   1.588   1.473   1.479   1.602
243   Q         1.353   1.357   1.436   1.411   1.416   1.540   1.473   1.479   1.602
244   V         1.353   1.357   1.436   1.333   1.339   1.465   1.473   1.479   1.602
245   L         1.353   1.357   1.436   1.217   1.224   1.353   1.473   1.479   1.602
246   Y         0.190   0.196   0.306  -0.004   0.004   0.177  -0.209  -0.198  -0.040
247   S         0.119   0.116  -0.164   0.224   0.222  -0.199   0.107   0.102  -0.312
248   H        -0.448  -0.491  -0.695  -0.099  -0.158  -0.480  -0.419  -0.473  -0.714
249   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
250   E        -0.158  -0.161  -0.251  -0.230  -0.252  -0.387  -0.314  -0.333  -0.444
251   P         1.353   1.357   1.436   1.461   1.467   1.588   1.473   1.479   1.602
252   P         1.353   1.357   1.436   1.461   1.467   1.588   1.473   1.479   1.602
253   L         1.353   1.357   1.436   1.217   1.224   1.353   1.473   1.479   1.602
254   E         0.409   0.449   0.404   0.302   0.366   0.270   0.212   0.282   0.155
255   L         0.409   0.398   0.355   0.288   0.266   0.132   0.212   0.189   0.059
256   K        -0.158  -0.166  -0.249  -0.145  -0.164  -0.309  -0.314  -0.329  -0.443
257   R        -1.264  -1.277  -1.158  -1.329  -1.340  -1.159  -1.155  -1.161  -1.002
258   L         0.119   0.078  -0.165   0.189   0.134  -0.261   0.107   0.049  -0.312
259   Y        -1.555  -1.567  -1.463  -1.428  -1.444  -1.278  -1.260  -1.266  -1.120
260   Q        -0.863  -0.847  -0.800  -0.862  -0.836  -0.764  -0.945  -0.929  -0.838
261   P        -1.555  -1.576  -1.450  -1.374  -1.408  -1.235  -1.260  -1.272  -1.110
262   P        -1.845  -1.829  -1.712  -1.567  -1.542  -1.383  -1.365  -1.350  -1.198
263   K        -1.154  -1.141  -1.117  -1.075  -1.059  -1.036  -1.050  -1.039  -0.965
264   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
265   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
266   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
267   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
268   V        -1.348  -1.326  -1.189  -1.326  -1.307  -1.096  -1.218  -1.197  -1.027
269   A        -0.732  -0.745  -0.757  -0.666  -0.684  -0.708  -0.770  -0.785  -0.787
270   E        -1.845  -1.837  -1.715  -1.628  -1.614  -1.440  -1.365  -1.357  -1.200
271   Q        -0.448  -0.488  -0.679  -0.275  -0.327  -0.611  -0.419  -0.468  -0.695
272   S        -1.154  -1.201  -1.148  -1.082  -1.150  -1.093  -1.050  -1.089  -0.991
273   R        -1.445  -1.438  -1.451  -1.244  -1.242  -1.253  -1.155  -1.147  -1.110
274   R         0.243   0.248   0.328   0.165   0.171   0.275  -0.104  -0.096   0.004
275   F         0.190   0.195   0.306  -0.004   0.003   0.177  -0.209  -0.201  -0.040
276   I         0.243   0.248   0.328   0.007   0.014   0.130  -0.104  -0.096   0.004
277   T         1.353   1.357   1.436   1.385   1.391   1.515   1.473   1.479   1.602
278   F         1.353   1.357   1.436   1.354   1.360   1.484   1.473   1.479   1.602
279   V         1.353   1.357   1.436   1.333   1.339   1.465   1.473   1.479   1.602
280   L         1.353   1.357   1.436   1.217   1.224   1.353   1.473   1.479   1.602
281   F         1.353   1.357   1.436   1.354   1.360   1.484   1.473   1.479   1.602
282   P         0.721   0.675   0.500   0.893   0.832   0.559   0.737   0.664   0.336
283   R         1.353   1.357   1.436   1.348   1.353   1.479   1.473   1.479   1.602
284   H         1.353   1.357   1.436   1.521   1.527   1.646   1.473   1.479   1.602
285   F        -0.282  -0.299  -0.288  -0.527  -0.545  -0.487  -0.524  -0.543  -0.504
286   Q        -1.264  -1.252  -1.165  -1.299  -1.283  -1.153  -1.155  -1.143  -1.008
287   T        -1.555  -1.526  -1.465  -1.484  -1.436  -1.378  -1.260  -1.236  -1.121
288   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
289   K        -1.555  -1.521  -1.455  -1.480  -1.427  -1.339  -1.260  -1.232  -1.114
290   E        -0.754  -0.763  -0.765  -0.846  -0.855  -0.827  -0.840  -0.846  -0.802
291   L        -0.282  -0.298  -0.288  -0.479  -0.497  -0.430  -0.524  -0.540  -0.501
292   Q        -1.154  -1.154  -1.130  -1.061  -1.057  -0.995  -1.050  -1.046  -0.975
293   F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
294   H        -0.863  -0.872  -0.797  -0.860  -0.879  -0.749  -0.945  -0.955  -0.835
295   S        -0.282  -0.298  -0.288  -0.234  -0.255  -0.245  -0.524  -0.540  -0.501
296   I         0.409   0.414   0.390   0.325   0.332   0.261   0.212   0.218   0.127
297   C         0.721   0.727   0.506   0.815   0.826   0.553   0.737   0.746   0.348
298   Q         0.243   0.248   0.328   0.202   0.209   0.314  -0.104  -0.096   0.004
299   L         0.243   0.248   0.328  -0.047  -0.039   0.068  -0.104  -0.096   0.004
300   T        -0.682  -0.668  -0.741  -0.634  -0.611  -0.735  -0.734  -0.714  -0.771
301   L        -0.973  -0.984  -1.097  -0.976  -0.994  -1.173  -0.840  -0.852  -0.941
302   F         1.353   1.357   1.436   1.354   1.360   1.484   1.473   1.479   1.602
303   R         1.353   1.357   1.436   1.348   1.353   1.479   1.473   1.479   1.602
304   N        -0.158  -0.136  -0.240  -0.105  -0.073  -0.254  -0.314  -0.288  -0.427
305   Y         0.721   0.675   0.500   0.903   0.846   0.581   0.737   0.664   0.336
306   F         0.721   0.675   0.500   0.770   0.709   0.425   0.737   0.664   0.336
307   H         1.353   1.357   1.436   1.521   1.527   1.646   1.473   1.479   1.602
308   Y         0.721   0.675   0.500   0.899   0.841   0.571   0.737   0.664   0.336
309   H         1.353   1.357   1.436   1.521   1.527   1.646   1.473   1.479   1.602
310   I         1.353   1.357   1.436   1.354   1.360   1.484   1.473   1.479   1.602
311   K         1.353   1.357   1.436   1.348   1.356   1.479   1.473   1.479   1.602
312   C         0.409   0.370   0.369   0.590   0.518   0.466   0.212   0.137   0.087
313   S         0.721   0.700   0.500   0.780   0.756   0.465   0.737   0.704   0.336
314   K         1.353   1.357   1.436   1.348   1.356   1.479   1.473   1.479   1.602
315   A         1.353   1.357   1.436   1.380   1.382   1.510   1.473   1.479   1.602
316   Y         1.353   1.357   1.436   1.463   1.471   1.590   1.473   1.479   1.602
317   M         0.721   0.695   0.504   1.007   0.973   0.677   0.737   0.697   0.343
318   H         1.353   1.357   1.436   1.521   1.527   1.646   1.473   1.479   1.602
319   S         0.721   0.675   0.500   0.785   0.729   0.476   0.737   0.664   0.336
320   R         1.353   1.357   1.436   1.348   1.353   1.479   1.473   1.479   1.602
321   M         1.353   1.357   1.436   1.571   1.577   1.694   1.473   1.479   1.602
322   R         1.353   1.357   1.436   1.348   1.353   1.479   1.473   1.479   1.602
323   F        -0.392  -0.414  -0.325  -0.520  -0.560  -0.430  -0.629  -0.661  -0.545
324   R         1.353   1.357   1.436   1.348   1.353   1.479   1.473   1.479   1.602
325   V         0.721   0.695   0.504   0.774   0.742   0.467   0.737   0.697   0.343
326   D        -0.863  -0.848  -0.799  -0.989  -0.968  -0.889  -0.945  -0.930  -0.837
327   S        -0.863  -0.872  -0.797  -1.007  -1.023  -0.901  -0.945  -0.955  -0.835
328   F         0.721   0.750   0.510   0.806   0.843   0.521   0.737   0.782   0.354
329   I        -0.682  -0.703  -0.750  -0.818  -0.848  -0.904  -0.734  -0.759  -0.783
330   K         0.721   0.695   0.504   0.792   0.762   0.489   0.737   0.697   0.343
331   V         0.721   0.750   0.510   0.769   0.807   0.467   0.737   0.782   0.354
332   L         1.353   1.357   1.436   1.217   1.224   1.353   1.473   1.479   1.602
333   N         0.721   0.695   0.504   0.889   0.860   0.567   0.737   0.697   0.343
334   R         1.353   1.357   1.436   1.348   1.353   1.479   1.473   1.479   1.602
335   A         1.353   1.357   1.436   1.380   1.382   1.510   1.473   1.479   1.602
336   K         0.721   0.695   0.504   0.783   0.753   0.469   0.737   0.697   0.343
337   V        -0.682  -0.670  -0.742  -0.628  -0.608  -0.752  -0.734  -0.716  -0.773
338   D         0.243   0.271   0.332   0.008   0.063   0.137  -0.104  -0.051   0.013
339   E        -0.754  -0.793  -0.772  -0.789  -0.841  -0.801  -0.840  -0.873  -0.809
340   D        -1.122  -1.077  -1.122  -1.153  -1.080  -1.196  -0.998  -0.950  -0.965
341   D         0.513   0.500   0.401   0.506   0.485   0.298   0.397   0.372   0.149
342   E         0.224   0.223   0.315  -0.009  -0.015   0.124  -0.142  -0.146  -0.021
343   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
344   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
345   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
346   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
347   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
348   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
349   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
350   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
351   R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
352   Q        -1.555  -1.537  -1.466  -1.550  -1.526  -1.419  -1.260  -1.244  -1.122
353   Q        -1.555  -1.565  -1.468  -1.594  -1.613  -1.474  -1.260  -1.264  -1.123
354   A        -0.754  -0.760  -0.763  -0.788  -0.799  -0.787  -0.840  -0.842  -0.800
355   R         0.409   0.409   0.383   0.324   0.322   0.250   0.212   0.209   0.114
356   R         0.243   0.248   0.328   0.017   0.025   0.139  -0.104  -0.096   0.004
357   T         1.353   1.357   1.436   1.385   1.391   1.515   1.473   1.479   1.602
358   F        -0.158  -0.152  -0.257  -0.172  -0.168  -0.341  -0.314  -0.306  -0.451
359   T         0.190   0.195   0.306  -0.070  -0.060   0.116  -0.209  -0.201  -0.040
360   G         1.353   1.357   1.436   1.515   1.521   1.640   1.473   1.479   1.602
361   R         1.353   1.357   1.436   1.348   1.353   1.479   1.473   1.479   1.602
362   K        -0.863  -0.875  -0.800  -0.989  -1.000  -0.889  -0.945  -0.950  -0.837
363   I        -0.158  -0.152  -0.257  -0.113  -0.105  -0.255  -0.314  -0.306  -0.451
364   V        -0.392  -0.368  -0.314  -0.586  -0.544  -0.481  -0.629  -0.595  -0.529
365   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
366   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
367   -        -0.242  -0.238  -0.291  -0.244  -0.240  -0.317  -0.411  -0.405  -0.496
368   Y        -0.754  -0.716  -0.759  -0.726  -0.681  -0.718  -0.840  -0.802  -0.796
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P53731
Output conservation file - output/P53731
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
