1     M         1.261   1.276   1.363   1.486   1.504   1.620   1.346   1.367   1.502
2     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     T         0.097   0.084   0.206  -0.035  -0.067   0.113  -0.264  -0.299  -0.127
5     R        -1.673  -1.719  -1.623  -1.352  -1.439  -1.366  -1.338  -1.372  -1.217
6     P        -0.421  -0.394  -0.424  -0.426  -0.399  -0.498  -0.617  -0.599  -0.614
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    K        -0.873  -0.954  -0.904  -0.931  -1.009  -0.878  -0.908  -1.000  -0.901
16    T        -0.568  -0.524  -0.454  -0.727  -0.668  -0.590  -0.801  -0.743  -0.650
17    F         0.097   0.100   0.209   0.015   0.015   0.173  -0.264  -0.268  -0.121
18    F         1.261   1.276   1.363   1.315   1.332   1.461   1.346   1.367   1.502
19    D        -0.033  -0.185  -0.329  -0.008  -0.231  -0.504  -0.049  -0.262  -0.474
20    I         0.598   0.566   0.378   0.741   0.702   0.419   0.595   0.543   0.197
21    S        -0.033  -0.118  -0.323   0.154   0.040  -0.308  -0.049  -0.166  -0.467
22    I        -0.033   0.077  -0.293   0.184   0.327  -0.191  -0.049   0.100  -0.423
23    G        -0.323  -0.316  -0.390  -0.387  -0.398  -0.500  -0.479  -0.484  -0.568
24    G         1.261   1.276   1.363   1.220   1.234   1.372   1.346   1.367   1.502
25    K         0.598   0.670   0.394   0.441   0.535   0.180   0.595   0.699   0.225
26    P        -0.628  -0.806  -0.867  -0.354  -0.619  -0.764  -0.586  -0.800  -0.855
27    Q        -1.063  -1.076  -0.932  -1.313  -1.302  -1.061  -1.123  -1.127  -0.931
28    G         0.598   0.475   0.375   0.654   0.495   0.355   0.595   0.399   0.191
29    R        -0.033  -0.185  -0.329   0.247   0.027  -0.262  -0.049  -0.262  -0.474
30    I         0.272   0.347   0.302   0.272   0.392   0.285   0.058   0.184   0.056
31    V         0.272   0.190   0.238   0.275   0.145   0.196   0.058  -0.097  -0.066
32    F         1.261   1.276   1.363   1.315   1.332   1.461   1.346   1.367   1.502
33    E         0.598   0.646   0.391   0.590   0.656   0.253   0.595   0.664   0.220
34    L         1.261   1.276   1.363   1.195   1.216   1.349   1.346   1.367   1.502
35    Y         0.272   0.190   0.238   0.360   0.213   0.244   0.058  -0.097  -0.066
36    N        -1.368  -1.319  -1.276  -1.392  -1.338  -1.296  -1.231  -1.185  -1.072
37    D         0.598   0.475   0.375   0.623   0.469   0.316   0.595   0.399   0.191
38    I        -0.323  -0.340  -0.389  -0.336  -0.357  -0.486  -0.479  -0.496  -0.567
39    V         1.261   1.276   1.363   1.283   1.304   1.431   1.346   1.367   1.502
40    P         1.261   1.276   1.363   1.367   1.385   1.509   1.346   1.367   1.502
41    K         1.261   1.276   1.363   1.015   1.040   1.181   1.346   1.367   1.502
42    T         1.261   1.276   1.363   1.305   1.323   1.451   1.346   1.367   1.502
43    A         0.598   0.475   0.375   0.555   0.391   0.248   0.595   0.399   0.191
44    E        -0.033  -0.114  -0.310  -0.010  -0.139  -0.487  -0.049  -0.168  -0.448
45    N         1.261   1.276   1.363   1.317   1.334   1.462   1.346   1.367   1.502
46    F         1.261   1.276   1.363   1.315   1.332   1.461   1.346   1.367   1.502
47    L        -0.453  -0.493  -0.416  -0.502  -0.532  -0.448  -0.694  -0.713  -0.602
48    K        -0.643  -0.632  -0.471  -1.081  -1.036  -0.768  -0.908  -0.889  -0.674
49    L         1.261   1.276   1.363   1.195   1.216   1.349   1.346   1.367   1.502
50    C         1.261   1.276   1.363   1.502   1.519   1.635   1.346   1.367   1.502
51    E        -0.453  -0.493  -0.416  -0.565  -0.582  -0.472  -0.694  -0.713  -0.602
52    G         1.261   1.276   1.363   1.220   1.234   1.372   1.346   1.367   1.502
53    N        -1.368  -1.332  -1.284  -1.403  -1.329  -1.300  -1.231  -1.183  -1.077
54    A        -0.873  -0.846  -0.888  -1.092  -1.044  -1.101  -0.908  -0.867  -0.881
55    G         1.261   1.276   1.363   1.216   1.227   1.368   1.346   1.367   1.502
56    M        -1.815  -1.801  -1.637  -1.526  -1.518  -1.331  -1.458  -1.437  -1.228
57    A        -0.986  -1.056  -0.940  -1.098  -1.200  -1.005  -1.038  -1.097  -0.936
58    K        -0.411  -0.451  -0.452  -0.684  -0.738  -0.720  -0.578  -0.636  -0.647
59    T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
60    K        -0.033   0.003  -0.300  -0.102  -0.048  -0.428  -0.049  -0.004  -0.433
61    P        -1.368  -1.449  -1.315  -1.265  -1.404  -1.250  -1.231  -1.288  -1.104
62    D         0.097   0.179   0.246  -0.177  -0.027   0.054  -0.264  -0.119  -0.050
63    V        -1.063  -1.078  -0.930  -1.251  -1.235  -0.988  -1.123  -1.120  -0.927
64    P        -0.033  -0.081  -0.304   0.276   0.215  -0.080  -0.049  -0.126  -0.439
65    L         1.261   1.276   1.363   1.195   1.216   1.349   1.346   1.367   1.502
66    S        -0.453  -0.528  -0.421  -0.382  -0.466  -0.311  -0.694  -0.771  -0.614
67    Y         0.598   0.566   0.378   0.827   0.786   0.502   0.595   0.543   0.197
68    K         1.261   1.276   1.363   1.015   1.040   1.181   1.346   1.367   1.502
69    G         0.598   0.646   0.391   0.630   0.687   0.324   0.595   0.664   0.220
70    S         1.261   1.276   1.363   1.322   1.341   1.467   1.346   1.367   1.502
71    I        -0.628  -0.806  -0.867  -0.343  -0.584  -0.689  -0.586  -0.800  -0.855
72    F         1.261   1.276   1.363   1.315   1.332   1.461   1.346   1.367   1.502
73    H         1.261   1.276   1.363   1.489   1.507   1.623   1.346   1.367   1.502
74    R         1.261   1.276   1.363   1.433   1.446   1.571   1.346   1.367   1.502
75    V         0.598   0.683   0.396   0.710   0.817   0.428   0.595   0.718   0.229
76    I         1.261   1.276   1.363   1.318   1.337   1.464   1.346   1.367   1.502
77    K         1.261   1.276   1.363   1.015   1.040   1.181   1.346   1.367   1.502
78    D        -0.628  -0.715  -0.850  -0.465  -0.583  -0.761  -0.586  -0.698  -0.835
79    F         1.261   1.276   1.363   1.315   1.332   1.461   1.346   1.367   1.502
80    M         1.261   1.276   1.363   1.486   1.504   1.620   1.346   1.367   1.502
81    C        -0.873  -0.979  -0.897  -0.617  -0.788  -0.714  -0.908  -1.016  -0.893
82    Q         1.261   1.276   1.363   1.410   1.424   1.549   1.346   1.367   1.502
83    F         0.097   0.179   0.246  -0.113   0.023   0.116  -0.264  -0.119  -0.050
84    G         1.261   1.276   1.363   1.220   1.234   1.372   1.346   1.367   1.502
85    D         1.261   1.276   1.363   1.195   1.219   1.349   1.346   1.367   1.502
86    F         1.261   1.276   1.363   1.315   1.332   1.461   1.346   1.367   1.502
87    T         1.261   1.276   1.363   1.305   1.323   1.451   1.346   1.367   1.502
88    N        -0.948  -0.949  -0.905  -0.947  -0.952  -0.810  -1.016  -1.005  -0.901
89    F        -0.453  -0.366  -0.398  -0.558  -0.427  -0.431  -0.694  -0.567  -0.578
90    N        -0.323  -0.207  -0.350  -0.270  -0.095  -0.328  -0.479  -0.316  -0.506
91    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
92    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
93    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
94    G         1.261   1.276   1.363   1.220   1.234   1.372   1.346   1.367   1.502
95    T         0.598   0.683   0.396   0.732   0.835   0.447   0.595   0.718   0.229
96    G         1.261   1.276   1.363   1.220   1.234   1.372   1.346   1.367   1.502
97    G         1.261   1.276   1.363   1.220   1.234   1.372   1.346   1.367   1.502
98    E         1.261   1.276   1.363   1.206   1.226   1.359   1.346   1.367   1.502
99    S         1.261   1.276   1.363   1.322   1.341   1.467   1.346   1.367   1.502
100   I         1.261   1.276   1.363   1.318   1.337   1.464   1.346   1.367   1.502
101   Y         1.261   1.276   1.363   1.400   1.417   1.540   1.346   1.367   1.502
102   D         0.598   0.691   0.397   0.630   0.742   0.333   0.595   0.731   0.231
103   E         0.598   0.550   0.379   0.607   0.545   0.268   0.595   0.519   0.198
104   K         1.261   1.276   1.363   1.015   1.040   1.181   1.346   1.367   1.502
105   F         1.261   1.276   1.363   1.315   1.332   1.461   1.346   1.367   1.502
106   E         0.598   0.566   0.378   0.641   0.605   0.348   0.595   0.543   0.197
107   D         1.261   1.276   1.363   1.195   1.219   1.349   1.346   1.367   1.502
108   E         1.261   1.276   1.363   1.206   1.226   1.359   1.346   1.367   1.502
109   N         0.598   0.566   0.378   0.718   0.674   0.368   0.595   0.543   0.197
110   F         1.261   1.276   1.363   1.315   1.332   1.461   1.346   1.367   1.502
111   T        -1.483  -1.450  -1.309  -1.453  -1.398  -1.209  -1.338  -1.296  -1.100
112   V        -0.628  -0.537  -0.823  -0.474  -0.351  -0.740  -0.586  -0.478  -0.804
113   K        -0.628  -0.565  -0.831  -0.656  -0.566  -0.900  -0.586  -0.511  -0.813
114   H         1.261   1.276   1.363   1.489   1.507   1.623   1.346   1.367   1.502
115   D         0.598   0.646   0.391   0.623   0.688   0.342   0.595   0.664   0.220
116   K        -0.033  -0.118  -0.323  -0.082  -0.177  -0.418  -0.049  -0.166  -0.467
117   P         1.261   1.276   1.363   1.367   1.385   1.509   1.346   1.367   1.502
118   F         1.261   1.276   1.363   1.315   1.332   1.461   1.346   1.367   1.502
119   L         1.261   1.276   1.363   1.195   1.216   1.349   1.346   1.367   1.502
120   L         1.261   1.276   1.363   1.195   1.216   1.349   1.346   1.367   1.502
121   S         1.261   1.276   1.363   1.322   1.341   1.467   1.346   1.367   1.502
122   M         1.261   1.276   1.363   1.486   1.504   1.620   1.346   1.367   1.502
123   A         1.261   1.276   1.363   1.133   1.146   1.291   1.346   1.367   1.502
124   N         1.261   1.276   1.363   1.317   1.334   1.462   1.346   1.367   1.502
125   A         0.598   0.646   0.391   0.561   0.616   0.287   0.595   0.664   0.220
126   G         1.261   1.276   1.363   1.220   1.234   1.372   1.346   1.367   1.502
127   P         0.272   0.370   0.275   0.272   0.434   0.209   0.058   0.224   0.005
128   N         0.598   0.550   0.379   0.730   0.667   0.397   0.595   0.519   0.198
129   T         1.261   1.276   1.363   1.305   1.323   1.451   1.346   1.367   1.502
130   N         1.261   1.276   1.363   1.317   1.334   1.462   1.346   1.367   1.502
131   G         1.261   1.276   1.363   1.220   1.234   1.372   1.346   1.367   1.502
132   S         1.261   1.276   1.363   1.322   1.341   1.467   1.346   1.367   1.502
133   Q         1.261   1.276   1.363   1.410   1.424   1.549   1.346   1.367   1.502
134   A        -0.323  -0.177  -0.361  -0.283  -0.066  -0.320  -0.479  -0.274  -0.522
135   F         1.261   1.276   1.363   1.315   1.332   1.461   1.346   1.367   1.502
136   I         0.598   0.550   0.379   0.741   0.683   0.420   0.595   0.519   0.198
137   T         1.261   1.276   1.363   1.305   1.323   1.451   1.346   1.367   1.502
138   C         0.097   0.179   0.246   0.060   0.186   0.279  -0.264  -0.119  -0.050
139   V         0.598   0.566   0.378   0.708   0.673   0.395   0.595   0.543   0.197
140   P         0.598   0.566   0.378   0.778   0.737   0.437   0.595   0.543   0.197
141   T         1.261   1.276   1.363   1.305   1.323   1.451   1.346   1.367   1.502
142   P         1.261   1.276   1.363   1.367   1.385   1.509   1.346   1.367   1.502
143   H         1.261   1.276   1.363   1.489   1.507   1.623   1.346   1.367   1.502
144   L         1.261   1.276   1.363   1.195   1.216   1.349   1.346   1.367   1.502
145   D         0.598   0.683   0.396   0.623   0.731   0.349   0.595   0.718   0.229
146   G         0.598   0.566   0.378   0.647   0.604   0.343   0.595   0.543   0.197
147   K         1.261   1.276   1.363   1.015   1.040   1.181   1.346   1.367   1.502
148   H         1.261   1.276   1.363   1.489   1.507   1.623   1.346   1.367   1.502
149   V         1.261   1.276   1.363   1.283   1.304   1.431   1.346   1.367   1.502
150   V         1.261   1.276   1.363   1.283   1.304   1.431   1.346   1.367   1.502
151   F         1.261   1.276   1.363   1.315   1.332   1.461   1.346   1.367   1.502
152   G         1.261   1.276   1.363   1.220   1.234   1.372   1.346   1.367   1.502
153   E         0.272   0.190   0.238   0.077  -0.089  -0.070   0.058  -0.097  -0.066
154   V         0.598   0.566   0.378   0.693   0.655   0.358   0.595   0.543   0.197
155   I         0.272   0.229   0.246   0.244   0.163   0.135   0.058  -0.026  -0.051
156   Q        -0.568  -0.552  -0.457  -0.580  -0.557  -0.454  -0.801  -0.781  -0.654
157   G         1.261   1.276   1.363   1.220   1.234   1.372   1.346   1.367   1.502
158   K         1.261   1.276   1.363   1.015   1.040   1.181   1.346   1.367   1.502
159   R        -0.453  -0.427  -0.409  -0.433  -0.383  -0.363  -0.694  -0.636  -0.593
160   I        -0.873  -0.945  -0.888  -0.811  -0.890  -0.839  -0.908  -0.969  -0.880
161   V         1.261   1.276   1.363   1.283   1.304   1.431   1.346   1.367   1.502
162   R         1.261   1.276   1.363   1.433   1.446   1.571   1.346   1.367   1.502
163   L        -0.568  -0.526  -0.444  -0.591  -0.521  -0.440  -0.801  -0.744  -0.638
164   I         0.272   0.347   0.302   0.244   0.368   0.249   0.058   0.184   0.056
165   E         1.261   1.276   1.363   1.206   1.226   1.359   1.346   1.367   1.502
166   N        -0.453  -0.383  -0.404  -0.476  -0.377  -0.422  -0.694  -0.607  -0.589
167   Q        -1.788  -1.693  -1.618  -1.511  -1.413  -1.265  -1.445  -1.358  -1.214
168   Q        -1.368  -1.261  -1.277  -1.400  -1.247  -1.319  -1.231  -1.115  -1.071
169   C        -0.323  -0.188  -0.347  -0.335  -0.131  -0.355  -0.479  -0.294  -0.502
170   D        -0.519  -0.442  -0.446  -0.738  -0.610  -0.636  -0.753  -0.647  -0.641
171   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
172   E        -1.178  -1.232  -1.252  -1.112  -1.220  -1.280  -1.016  -1.074  -1.046
173   N        -1.178  -1.146  -1.245  -0.934  -0.892  -1.075  -1.016  -0.981  -1.040
174   N         0.598   0.691   0.397   0.623   0.741   0.351   0.595   0.731   0.231
175   K        -0.323  -0.423  -0.398  -0.511  -0.642  -0.584  -0.479  -0.605  -0.578
176   P         1.261   1.276   1.363   1.367   1.385   1.509   1.346   1.367   1.502
177   L        -1.673  -1.593  -1.598  -1.526  -1.410  -1.467  -1.338  -1.260  -1.198
178   R        -1.788  -1.765  -1.619  -1.700  -1.672  -1.392  -1.445  -1.415  -1.215
179   D        -0.323  -0.328  -0.399  -0.365  -0.391  -0.480  -0.479  -0.520  -0.581
180   V        -0.323  -0.308  -0.370  -0.223  -0.198  -0.307  -0.479  -0.442  -0.536
181   K        -0.873  -0.894  -0.901  -1.041  -1.068  -1.017  -0.908  -0.948  -0.897
182   I         0.598   0.670   0.394   0.741   0.831   0.445   0.595   0.699   0.225
183   D        -1.368  -1.292  -1.281  -1.431  -1.328  -1.293  -1.231  -1.158  -1.077
184   D        -0.033  -0.093  -0.306   0.026  -0.059  -0.391  -0.049  -0.141  -0.442
185   C         1.261   1.276   1.363   1.502   1.519   1.635   1.346   1.367   1.502
186   G         1.261   1.276   1.363   1.220   1.234   1.372   1.346   1.367   1.502
187   V        -0.873  -0.853  -0.888  -0.894  -0.844  -0.913  -0.908  -0.871  -0.881
188   L         0.598   0.475   0.375   0.651   0.506   0.381   0.595   0.399   0.191
189   P        -0.033  -0.198  -0.332   0.229   0.006  -0.220  -0.049  -0.279  -0.479
190   D        -1.483  -1.507  -1.314  -1.671  -1.735  -1.428  -1.338  -1.339  -1.104
191   D         0.598   0.646   0.391   0.623   0.688   0.342   0.595   0.664   0.220
192   Y        -0.628  -0.806  -0.867  -0.302  -0.560  -0.701  -0.586  -0.800  -0.855
193   Q        -1.466  -1.430  -1.302  -1.411  -1.369  -1.182  -1.318  -1.278  -1.094
194   V         0.209   0.262   0.270   0.158   0.244   0.230  -0.056   0.033  -0.005
195   P        -0.421  -0.457  -0.418  -0.372  -0.410  -0.383  -0.617  -0.652  -0.602
196   E        -0.769  -0.717  -0.856  -0.764  -0.703  -0.893  -0.757  -0.697  -0.842
197   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
198   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
199   E         0.381   0.305   0.285   0.313   0.193   0.120   0.247   0.110   0.024
200   A        -1.368  -1.320  -1.283  -1.350  -1.297  -1.189  -1.231  -1.179  -1.078
201   T        -1.673  -1.719  -1.623  -1.475  -1.563  -1.455  -1.338  -1.372  -1.217
202   P        -1.368  -1.424  -1.308  -1.305  -1.419  -1.285  -1.231  -1.270  -1.099
203   T        -0.948  -1.025  -0.921  -1.015  -1.105  -0.955  -1.016  -1.074  -0.917
204   D         1.261   1.276   1.363   1.195   1.219   1.349   1.346   1.367   1.502
205   E        -1.063  -1.081  -0.932  -1.273  -1.285  -1.066  -1.123  -1.124  -0.929
206   Y        -0.453  -0.378  -0.411  -0.447  -0.345  -0.362  -0.694  -0.598  -0.601
207   G         1.261   1.276   1.363   1.220   1.234   1.372   1.346   1.367   1.502
208   D         1.261   1.276   1.363   1.195   1.219   1.349   1.346   1.367   1.502
209   N        -1.673  -1.719  -1.623  -1.435  -1.522  -1.406  -1.338  -1.372  -1.217
210   Y         0.598   0.475   0.375   0.810   0.642   0.457   0.595   0.399   0.191
211   E         1.261   1.276   1.363   1.206   1.226   1.359   1.346   1.367   1.502
212   D         0.097   0.106   0.207  -0.190  -0.177  -0.036  -0.264  -0.257  -0.125
213   V        -1.368  -1.204  -1.272  -1.213  -0.964  -1.067  -1.231  -1.057  -1.068
214   L        -0.873  -0.816  -0.888  -0.794  -0.741  -0.767  -0.908  -0.870  -0.883
215   K        -1.368  -1.389  -1.290  -1.577  -1.603  -1.443  -1.231  -1.238  -1.084
216   Q         0.598   0.691   0.397   0.637   0.752   0.382   0.595   0.731   0.231
217   D        -0.873  -0.990  -0.905  -0.863  -1.011  -0.887  -0.908  -1.028  -0.901
218   E        -1.063  -1.016  -0.934  -1.282  -1.225  -1.072  -1.123  -1.077  -0.932
219   K        -0.637  -0.637  -0.479  -0.966  -0.938  -0.675  -0.897  -0.896  -0.684
220   V        -0.421  -0.457  -0.418  -0.462  -0.507  -0.481  -0.617  -0.652  -0.602
221   D        -0.323  -0.333  -0.398  -0.401  -0.458  -0.519  -0.479  -0.529  -0.579
222   L        -1.788  -1.780  -1.624  -1.643  -1.626  -1.378  -1.445  -1.425  -1.218
223   K        -0.453  -0.479  -0.418  -0.660  -0.691  -0.572  -0.694  -0.715  -0.609
224   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
225   N        -1.063  -1.012  -0.928  -1.202  -1.115  -1.007  -1.123  -1.072  -0.926
226   F        -1.368  -1.378  -1.299  -1.251  -1.278  -1.186  -1.231  -1.227  -1.091
227   D        -2.093  -2.072  -1.881  -1.921  -1.892  -1.618  -1.553  -1.526  -1.297
228   T        -0.873  -0.942  -0.888  -0.856  -0.966  -0.947  -0.908  -0.965  -0.879
229   V         0.272   0.184   0.238   0.249   0.099   0.153   0.058  -0.110  -0.066
230   L        -0.453  -0.399  -0.405  -0.587  -0.518  -0.479  -0.694  -0.635  -0.593
231   K        -0.628  -0.565  -0.823  -0.724  -0.636  -1.012  -0.586  -0.511  -0.805
232   A         0.272   0.184   0.238   0.104  -0.048   0.033   0.058  -0.110  -0.066
233   I        -0.643  -0.645  -0.477  -0.852  -0.875  -0.618  -0.908  -0.906  -0.682
234   E        -0.568  -0.584  -0.467  -0.713  -0.736  -0.561  -0.801  -0.823  -0.668
235   T        -1.063  -1.027  -0.935  -1.311  -1.282  -1.146  -1.123  -1.091  -0.933
236   V        -0.948  -0.929  -0.901  -0.953  -0.908  -0.820  -1.016  -0.982  -0.896
237   K         1.261   1.276   1.363   1.015   1.040   1.181   1.346   1.367   1.502
238   N        -1.178  -1.181  -1.248  -1.053  -1.069  -1.173  -1.016  -1.024  -1.042
239   I         0.598   0.550   0.379   0.745   0.688   0.430   0.595   0.519   0.198
240   G         0.598   0.475   0.375   0.621   0.446   0.274   0.595   0.399   0.191
241   T         0.272   0.184   0.238   0.269   0.114   0.170   0.058  -0.110  -0.066
242   E         0.598   0.691   0.397   0.426   0.548   0.151   0.595   0.731   0.231
243   Q        -0.323  -0.364  -0.393  -0.240  -0.309  -0.416  -0.479  -0.530  -0.571
244   F         0.272   0.347   0.302   0.241   0.363   0.246   0.058   0.184   0.056
245   K         0.598   0.475   0.375   0.415   0.251   0.088   0.595   0.399   0.191
246   K        -1.178  -1.192  -1.245  -1.118  -1.131  -1.278  -1.016  -1.035  -1.040
247   Q        -0.453  -0.386  -0.416  -0.569  -0.478  -0.523  -0.694  -0.619  -0.607
248   N        -0.033  -0.045  -0.305   0.113   0.097  -0.356  -0.049  -0.068  -0.440
249   Y        -1.368  -1.252  -1.275  -1.306  -1.150  -1.178  -1.231  -1.106  -1.069
250   S        -1.178  -1.192  -1.245  -1.054  -1.085  -1.179  -1.016  -1.035  -1.040
251   V        -1.178  -1.213  -1.266  -1.062  -1.117  -1.290  -1.016  -1.055  -1.060
252   A         0.598   0.646   0.391   0.561   0.616   0.287   0.595   0.664   0.220
253   L        -0.323  -0.370  -0.374  -0.337  -0.387  -0.401  -0.479  -0.524  -0.541
254   E        -1.368  -1.378  -1.287  -1.522  -1.565  -1.429  -1.231  -1.234  -1.082
255   K         1.261   1.276   1.363   1.015   1.040   1.181   1.346   1.367   1.502
256   Y         0.598   0.475   0.375   0.861   0.714   0.577   0.595   0.399   0.191
257   V        -2.093  -1.952  -1.879  -1.900  -1.652  -1.632  -1.553  -1.436  -1.295
258   K         1.261   1.276   1.363   1.015   1.040   1.181   1.346   1.367   1.502
259   C        -0.873  -0.795  -0.879  -0.847  -0.750  -0.836  -0.908  -0.804  -0.870
260   D        -1.483  -1.435  -1.310  -1.510  -1.433  -1.231  -1.338  -1.281  -1.101
261   K        -1.788  -1.693  -1.618  -1.669  -1.484  -1.376  -1.445  -1.358  -1.214
262   F        -0.453  -0.337  -0.401  -0.388  -0.211  -0.269  -0.694  -0.535  -0.586
263   L         1.261   1.276   1.363   1.195   1.216   1.349   1.346   1.367   1.502
264   K        -0.948  -1.017  -0.918  -1.087  -1.123  -0.956  -1.016  -1.066  -0.914
265   E        -0.453  -0.373  -0.409  -0.634  -0.523  -0.512  -0.694  -0.597  -0.596
266   Y         0.598   0.550   0.379   0.810   0.748   0.464   0.595   0.519   0.198
267   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
268   F        -0.628  -0.806  -0.867  -0.388  -0.644  -0.771  -0.586  -0.800  -0.855
269   P         0.598   0.550   0.379   0.778   0.717   0.437   0.595   0.519   0.198
270   E        -1.368  -1.406  -1.288  -1.360  -1.416  -1.220  -1.231  -1.257  -1.083
271   D         0.598   0.646   0.391   0.609   0.674   0.310   0.595   0.664   0.220
272   L        -0.033  -0.198  -0.332   0.040  -0.186  -0.404  -0.049  -0.279  -0.479
273   E        -0.873  -0.758  -0.883  -0.782  -0.623  -0.801  -0.908  -0.779  -0.878
274   K        -0.568  -0.583  -0.462  -0.817  -0.852  -0.680  -0.801  -0.822  -0.661
275   E         0.598   0.550   0.379   0.607   0.545   0.268   0.595   0.519   0.198
276   Q        -0.873  -0.886  -0.877  -0.834  -0.852  -0.805  -0.908  -0.922  -0.870
277   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
278   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
279   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
280   I        -1.788  -1.773  -1.618  -1.598  -1.555  -1.327  -1.445  -1.421  -1.214
281   E        -1.368  -1.337  -1.286  -1.499  -1.447  -1.348  -1.231  -1.189  -1.079
282   K        -0.033  -0.114  -0.310  -0.141  -0.252  -0.524  -0.049  -0.168  -0.448
283   I        -0.948  -1.017  -0.918  -0.961  -1.030  -0.872  -1.016  -1.066  -0.914
284   N        -0.643  -0.618  -0.477  -0.686  -0.648  -0.463  -0.908  -0.874  -0.681
285   Q        -0.628  -0.469  -0.806  -0.572  -0.367  -0.828  -0.586  -0.392  -0.785
286   L         0.598   0.670   0.394   0.623   0.713   0.346   0.595   0.699   0.225
287   K         0.042   0.077   0.209  -0.264  -0.163   0.033  -0.372  -0.313  -0.122
288   V        -0.873  -0.944  -0.897  -0.813  -0.882  -0.830  -0.908  -0.970  -0.890
289   S         0.598   0.670   0.394   0.747   0.837   0.455   0.595   0.699   0.225
290   I        -1.063  -1.021  -0.934  -0.964  -0.914  -0.808  -1.123  -1.080  -0.933
291   P        -0.873  -0.795  -0.879  -0.653  -0.530  -0.671  -0.908  -0.804  -0.870
292   L        -0.033  -0.198  -0.332   0.031  -0.202  -0.425  -0.049  -0.279  -0.479
293   N         1.261   1.276   1.363   1.317   1.334   1.462   1.346   1.367   1.502
294   I        -0.948  -1.017  -0.918  -1.056  -1.153  -0.994  -1.016  -1.066  -0.914
295   A         1.261   1.276   1.363   1.133   1.146   1.291   1.346   1.367   1.502
296   I         0.272   0.367   0.315   0.165   0.314   0.216   0.058   0.219   0.080
297   C        -0.873  -0.793  -0.882  -0.701  -0.603  -0.697  -0.908  -0.835  -0.877
298   A        -0.033  -0.011  -0.308  -0.001   0.021  -0.373  -0.049  -0.024  -0.444
299   L         0.598   0.550   0.379   0.648   0.597   0.380   0.595   0.519   0.198
300   K         1.261   1.276   1.363   1.015   1.040   1.181   1.346   1.367   1.502
301   L        -0.873  -0.935  -0.883  -0.841  -0.899  -0.822  -0.908  -0.959  -0.875
302   K        -0.323  -0.431  -0.414  -0.534  -0.682  -0.619  -0.479  -0.636  -0.601
303   D        -1.673  -1.719  -1.607  -1.535  -1.648  -1.447  -1.338  -1.372  -1.206
304   Y        -1.063  -1.074  -0.940  -0.938  -0.936  -0.731  -1.123  -1.123  -0.937
305   K        -1.178  -1.207  -1.255  -1.153  -1.190  -1.202  -1.016  -1.049  -1.049
306   Q        -2.093  -1.952  -1.879  -1.927  -1.721  -1.620  -1.553  -1.436  -1.295
307   V        -1.063  -1.003  -0.917  -1.150  -1.047  -0.887  -1.123  -1.038  -0.912
308   L        -0.323  -0.182  -0.371  -0.260  -0.044  -0.320  -0.479  -0.277  -0.537
309   V        -1.788  -1.693  -1.618  -1.649  -1.495  -1.434  -1.445  -1.358  -1.214
310   A        -0.033  -0.198  -0.332  -0.001  -0.224  -0.410  -0.049  -0.279  -0.479
311   S        -0.033   0.108  -0.291   0.032   0.199  -0.284  -0.049   0.141  -0.421
312   S        -1.063  -1.084  -0.935  -1.069  -1.099  -0.888  -1.123  -1.134  -0.933
313   E        -1.368  -1.449  -1.315  -1.310  -1.411  -1.211  -1.231  -1.288  -1.104
314   V         0.097   0.110   0.219  -0.207  -0.192  -0.018  -0.264  -0.250  -0.103
315   L         0.598   0.475   0.375   0.623   0.468   0.316   0.595   0.399   0.191
316   Y        -1.368  -1.333  -1.292  -1.273  -1.240  -1.158  -1.231  -1.182  -1.084
317   A        -0.453  -0.461  -0.422  -0.685  -0.689  -0.610  -0.694  -0.692  -0.614
318   E        -0.628  -0.715  -0.850  -0.535  -0.665  -0.902  -0.586  -0.698  -0.835
319   A        -1.063  -1.049  -0.935  -1.157  -1.134  -0.920  -1.123  -1.109  -0.933
320   A        -1.368  -1.373  -1.297  -1.304  -1.290  -1.184  -1.231  -1.222  -1.088
321   D        -0.628  -0.806  -0.867  -0.523  -0.775  -0.896  -0.586  -0.800  -0.855
322   E        -0.873  -0.871  -0.887  -0.951  -0.953  -0.983  -0.908  -0.911  -0.883
323   K         0.598   0.475   0.375   0.424   0.266   0.111   0.595   0.399   0.191
324   A        -1.063  -1.068  -0.930  -1.214  -1.222  -1.022  -1.123  -1.117  -0.927
325   K         0.598   0.550   0.379   0.461   0.412   0.203   0.595   0.519   0.198
326   A        -0.323  -0.370  -0.374  -0.409  -0.454  -0.448  -0.479  -0.524  -0.541
327   K         1.261   1.276   1.363   1.015   1.040   1.181   1.346   1.367   1.502
328   A         1.261   1.276   1.363   1.133   1.146   1.291   1.346   1.367   1.502
329   L         0.598   0.475   0.375   0.635   0.484   0.345   0.595   0.399   0.191
330   Y         0.598   0.566   0.378   0.827   0.786   0.502   0.595   0.543   0.197
331   R         1.261   1.276   1.363   1.433   1.446   1.571   1.346   1.367   1.502
332   R        -0.323  -0.370  -0.374  -0.271  -0.321  -0.409  -0.479  -0.524  -0.541
333   G         1.261   1.276   1.363   1.220   1.234   1.372   1.346   1.367   1.502
334   L        -1.368  -1.449  -1.315  -1.126  -1.196  -0.989  -1.231  -1.288  -1.104
335   A         0.097   0.129   0.223  -0.242  -0.195  -0.048  -0.264  -0.212  -0.094
336   Y         0.272   0.184   0.238   0.390   0.240   0.293   0.058  -0.110  -0.066
337   Y        -1.673  -1.719  -1.623  -1.417  -1.524  -1.436  -1.338  -1.372  -1.217
338   H        -1.368  -1.333  -1.292  -1.192  -1.154  -1.068  -1.231  -1.182  -1.084
339   V        -1.368  -1.324  -1.290  -1.342  -1.298  -1.238  -1.231  -1.193  -1.084
340   N         0.272   0.367   0.315  -0.011   0.139   0.059   0.058   0.219   0.080
341   D         0.097   0.087   0.204  -0.134  -0.152   0.028  -0.264  -0.294  -0.131
342   T        -0.873  -0.849  -0.885  -0.895  -0.843  -0.918  -0.908  -0.869  -0.877
343   D        -0.453  -0.456  -0.412  -0.657  -0.642  -0.557  -0.694  -0.684  -0.601
344   M        -1.368  -1.419  -1.307  -1.093  -1.193  -1.055  -1.231  -1.267  -1.098
345   A         0.598   0.475   0.375   0.561   0.399   0.262   0.595   0.399   0.191
346   L        -0.421  -0.328  -0.398  -0.475  -0.341  -0.432  -0.617  -0.491  -0.575
347   N        -0.986  -0.908  -0.920  -1.225  -1.112  -1.086  -1.038  -0.958  -0.916
348   D        -0.421  -0.414  -0.424  -0.516  -0.509  -0.506  -0.617  -0.616  -0.613
349   L         1.261   1.276   1.363   1.190   1.210   1.345   1.346   1.367   1.502
350   E         0.598   0.566   0.378   0.633   0.596   0.330   0.595   0.543   0.197
351   M        -1.368  -1.373  -1.297  -1.355  -1.400  -1.312  -1.231  -1.222  -1.088
352   A         1.261   1.276   1.363   1.133   1.146   1.291   1.346   1.367   1.502
353   T        -0.453  -0.439  -0.411  -0.656  -0.618  -0.603  -0.694  -0.649  -0.596
354   T        -1.368  -1.409  -1.307  -1.371  -1.480  -1.324  -1.231  -1.260  -1.098
355   F        -0.873  -0.849  -0.885  -0.906  -0.886  -0.931  -0.908  -0.869  -0.877
356   Q        -1.063  -1.027  -0.941  -1.111  -1.115  -0.959  -1.123  -1.091  -0.938
357   P         0.598   0.475   0.375   0.780   0.614   0.436   0.595   0.399   0.191
358   N        -0.873  -0.837  -0.883  -0.799  -0.761  -0.820  -0.908  -0.866  -0.877
359   D         1.261   1.276   1.363   1.195   1.219   1.349   1.346   1.367   1.502
360   A        -0.948  -0.952  -0.900  -1.081  -1.072  -0.948  -1.016  -1.010  -0.897
361   A         1.261   1.276   1.363   1.133   1.146   1.291   1.346   1.367   1.502
362   I         1.261   1.276   1.363   1.318   1.337   1.464   1.346   1.367   1.502
363   L        -2.093  -2.077  -1.885  -1.958  -1.940  -1.687  -1.553  -1.528  -1.299
364   K         0.272   0.229   0.246  -0.011  -0.075  -0.050   0.058  -0.026  -0.051
365   A        -1.063  -1.074  -0.940  -1.423  -1.463  -1.236  -1.123  -1.123  -0.937
366   I         0.097   0.138   0.222  -0.133  -0.062   0.057  -0.264  -0.195  -0.096
367   H        -1.368  -1.320  -1.291  -1.198  -1.200  -1.098  -1.231  -1.189  -1.085
368   N        -0.948  -0.901  -0.893  -1.101  -1.029  -0.993  -1.016  -0.957  -0.891
369   T        -1.063  -1.058  -0.921  -1.161  -1.121  -0.943  -1.123  -1.096  -0.917
370   K        -0.033  -0.093  -0.306  -0.098  -0.166  -0.429  -0.049  -0.141  -0.442
371   L        -1.368  -1.271  -1.281  -1.374  -1.227  -1.183  -1.231  -1.147  -1.077
372   K        -0.948  -0.865  -0.892  -1.249  -1.143  -1.091  -1.016  -0.931  -0.890
373   R        -1.178  -1.136  -0.953  -1.392  -1.369  -1.083  -1.231  -1.179  -0.949
374   K        -0.033  -0.118  -0.323  -0.135  -0.241  -0.531  -0.049  -0.166  -0.467
375   Q        -1.788  -1.775  -1.622  -1.685  -1.682  -1.463  -1.445  -1.422  -1.217
376   Q        -1.178  -1.108  -1.255  -0.792  -0.700  -0.957  -1.016  -0.947  -1.050
377   N        -1.673  -1.640  -1.607  -1.302  -1.294  -1.266  -1.338  -1.307  -1.205
378   E        -1.063  -1.089  -0.931  -1.363  -1.412  -1.186  -1.123  -1.132  -0.928
379   K        -0.033  -0.185  -0.329  -0.131  -0.323  -0.530  -0.049  -0.262  -0.474
380   A        -0.323  -0.290  -0.388  -0.236  -0.221  -0.402  -0.479  -0.460  -0.564
381   K         0.598   0.475   0.375   0.457   0.312   0.189   0.595   0.399   0.191
382   K         0.598   0.550   0.379   0.415   0.358   0.095   0.595   0.519   0.198
383   S        -0.453  -0.427  -0.409  -0.698  -0.653  -0.639  -0.694  -0.636  -0.593
384   L        -0.643  -0.574  -0.454  -0.696  -0.568  -0.391  -0.908  -0.814  -0.651
385   S        -0.453  -0.486  -0.420  -0.657  -0.733  -0.642  -0.694  -0.728  -0.613
386   K         0.598   0.566   0.378   0.428   0.393   0.125   0.595   0.543   0.197
387   M         0.042   0.063   0.201  -0.016   0.016   0.219  -0.372  -0.339  -0.137
388   F         1.261   1.276   1.363   1.315   1.332   1.461   1.346   1.367   1.502
389   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
390   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
391   S        -0.628  -0.714  -0.839  -0.419  -0.545  -0.788  -0.586  -0.696  -0.823
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P53691
Output conservation file - output/P53691
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
