1     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
2     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
19    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
20    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
21    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
22    M         1.295   1.297   1.324   1.583   1.584   1.623   1.373   1.374   1.410
23    N        -0.815  -0.814  -0.822  -0.719  -0.724  -0.723  -0.831  -0.831  -0.825
24    S        -1.518  -1.512  -1.447  -1.453  -1.445  -1.335  -1.272  -1.264  -1.171
25    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
26    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
27    Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
28    Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
29    Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
30    E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
31    Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
32    Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
33    P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
34    I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
35    V        -0.111  -0.109  -0.061  -0.420  -0.415  -0.328  -0.390  -0.386  -0.311
36    F         1.295   1.297   1.324   1.469   1.471   1.511   1.373   1.374   1.410
37    V        -0.111  -0.106  -0.060  -0.420  -0.404  -0.322  -0.390  -0.381  -0.308
38    T         1.295   1.297   1.324   1.252   1.253   1.300   1.373   1.374   1.410
39    G         1.295   1.297   1.324   1.334   1.335   1.380   1.373   1.374   1.410
40    T         1.295   1.297   1.324   1.252   1.253   1.300   1.373   1.374   1.410
41    D         0.154   0.121   0.037   0.254   0.198   0.048   0.050  -0.002  -0.145
42    T         1.295   1.297   1.324   1.252   1.253   1.300   1.373   1.374   1.410
43    D         1.295   1.297   1.324   1.414   1.416   1.458   1.373   1.374   1.410
44    V         1.295   1.297   1.324   1.303   1.301   1.349   1.373   1.374   1.410
45    G         1.295   1.297   1.324   1.334   1.335   1.380   1.373   1.374   1.410
46    K         1.295   1.297   1.324   1.365   1.368   1.410   1.373   1.374   1.410
47    T         1.295   1.297   1.324   1.252   1.253   1.300   1.373   1.374   1.410
48    F         1.295   1.297   1.324   1.469   1.471   1.511   1.373   1.374   1.410
49    V         0.154   0.132   0.040   0.030  -0.000  -0.156   0.050   0.015  -0.140
50    S         1.295   1.297   1.324   1.359   1.365   1.404   1.373   1.374   1.410
51    T         0.154   0.132   0.040   0.192   0.153  -0.016   0.050   0.015  -0.140
52    L         1.295   1.297   1.324   1.078   1.082   1.131   1.373   1.374   1.410
53    L         1.295   1.297   1.324   1.078   1.082   1.131   1.373   1.374   1.410
54    V         0.154   0.187   0.053   0.119   0.167  -0.058   0.050   0.102  -0.117
55    H        -0.111  -0.106  -0.060  -0.133  -0.119  -0.042  -0.390  -0.381  -0.308
56    K        -0.815  -0.848  -0.845  -0.714  -0.766  -0.754  -0.831  -0.871  -0.853
57    W         0.154   0.121   0.037   0.351   0.290   0.096   0.050  -0.002  -0.145
58    K        -0.815  -0.770  -0.831  -0.777  -0.706  -0.802  -0.831  -0.774  -0.836
59    A         0.154   0.189   0.050   0.226   0.281   0.051   0.050   0.106  -0.123
60    A        -0.815  -0.848  -0.845  -0.758  -0.814  -0.803  -0.831  -0.871  -0.853
61    Y         1.295   1.297   1.324   1.583   1.586   1.623   1.373   1.374   1.410
62    W         1.295   1.297   1.324   1.595   1.598   1.634   1.373   1.374   1.410
63    K         1.295   1.297   1.324   1.365   1.368   1.410   1.373   1.374   1.410
64    P         0.154   0.121   0.037   0.226   0.174   0.030   0.050  -0.002  -0.145
65    V        -0.111  -0.106  -0.060  -0.420  -0.404  -0.322  -0.390  -0.381  -0.308
66    Q         1.295   1.297   1.324   1.499   1.501   1.541   1.373   1.374   1.410
67    T         1.295   1.297   1.324   1.252   1.253   1.300   1.373   1.374   1.410
68    G         1.295   1.297   1.324   1.334   1.335   1.380   1.373   1.374   1.410
69    I         0.154   0.132   0.040  -0.121  -0.155  -0.315   0.050   0.015  -0.140
70    E         0.154   0.189   0.050   0.192   0.245   0.021   0.050   0.106  -0.123
71    S         0.154   0.121   0.037   0.293   0.249   0.133   0.050  -0.002  -0.145
72    D        -0.111  -0.106  -0.060  -0.030  -0.031   0.049  -0.390  -0.381  -0.308
73    Q         0.154   0.121   0.037   0.311   0.252   0.087   0.050  -0.002  -0.145
74    G         0.154   0.189   0.050   0.166   0.218  -0.013   0.050   0.106  -0.123
75    D         1.295   1.297   1.324   1.414   1.416   1.458   1.373   1.374   1.410
76    S         0.154   0.132   0.040   0.105   0.069  -0.078   0.050   0.015  -0.140
77    E        -0.815  -0.813  -0.822  -0.724  -0.721  -0.723  -0.831  -0.829  -0.824
78    T         1.295   1.297   1.324   1.252   1.253   1.300   1.373   1.374   1.410
79    L        -0.815  -0.848  -0.845  -1.040  -1.110  -1.127  -0.831  -0.871  -0.853
80    K        -0.815  -0.814  -0.822  -0.729  -0.733  -0.735  -0.831  -0.831  -0.825
81    N        -0.815  -0.806  -0.821  -0.690  -0.684  -0.688  -0.831  -0.820  -0.823
82    F        -0.815  -0.770  -0.831  -0.887  -0.795  -0.958  -0.831  -0.774  -0.836
83    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
84    I         0.154   0.132   0.040   0.051   0.014  -0.155   0.050   0.015  -0.140
85    A        -1.518  -1.512  -1.447  -1.463  -1.457  -1.345  -1.272  -1.264  -1.171
86    A         0.154   0.132   0.040  -0.058  -0.092  -0.225   0.050   0.015  -0.140
87    S         0.154   0.121   0.037   0.174   0.121  -0.039   0.050  -0.002  -0.145
88    T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
89    W        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
90    Q        -1.518  -1.512  -1.447  -1.353  -1.344  -1.237  -1.272  -1.264  -1.171
91    P        -0.815  -0.770  -0.831  -0.761  -0.688  -0.786  -0.831  -0.774  -0.836
92    P        -1.518  -1.512  -1.447  -1.275  -1.276  -1.162  -1.272  -1.264  -1.171
93    I        -0.815  -0.848  -0.845  -0.887  -0.960  -0.995  -0.831  -0.871  -0.853
94    F        -0.111  -0.106  -0.060  -0.191  -0.178  -0.099  -0.390  -0.381  -0.308
95    T        -0.815  -0.808  -0.819  -0.766  -0.762  -0.772  -0.831  -0.822  -0.821
96    P         1.295   1.297   1.324   1.371   1.375   1.416   1.373   1.374   1.410
97    T        -1.518  -1.512  -1.447  -1.266  -1.267  -1.152  -1.272  -1.264  -1.171
98    Y        -0.815  -0.848  -0.845  -0.787  -0.824  -0.787  -0.831  -0.871  -0.853
99    A        -0.815  -0.848  -0.845  -0.742  -0.795  -0.777  -0.831  -0.871  -0.853
100   L         0.154   0.121   0.037  -0.026  -0.074  -0.184   0.050  -0.002  -0.145
101   Q        -0.815  -0.814  -0.822  -0.670  -0.674  -0.695  -0.831  -0.831  -0.825
102   K        -1.518  -1.512  -1.447  -1.467  -1.444  -1.348  -1.272  -1.264  -1.171
103   P         1.295   1.297   1.324   1.371   1.375   1.416   1.373   1.374   1.410
104   L         1.295   1.297   1.324   1.078   1.082   1.131   1.373   1.374   1.410
105   S         1.295   1.297   1.324   1.359   1.365   1.404   1.373   1.374   1.410
106   P         1.295   1.297   1.324   1.371   1.375   1.416   1.373   1.374   1.410
107   L        -0.815  -0.848  -0.845  -0.612  -0.675  -0.697  -0.831  -0.871  -0.853
108   Q        -0.815  -0.848  -0.845  -0.609  -0.666  -0.667  -0.831  -0.871  -0.853
109   A         1.295   1.297   1.324   1.377   1.379   1.422   1.373   1.374   1.410
110   M        -0.815  -0.770  -0.831  -0.597  -0.520  -0.646  -0.831  -0.774  -0.836
111   E        -0.111  -0.106  -0.060  -0.391  -0.372  -0.293  -0.390  -0.381  -0.308
112   Y        -1.518  -1.512  -1.447  -1.269  -1.252  -1.155  -1.272  -1.264  -1.171
113   E         1.295   1.297   1.324   1.340   1.342   1.386   1.373   1.374   1.410
114   P        -0.815  -0.848  -0.845  -0.785  -0.840  -0.835  -0.831  -0.871  -0.853
115   N        -1.518  -1.512  -1.447  -1.515  -1.506  -1.395  -1.272  -1.264  -1.171
116   V         0.004  -0.026  -0.019  -0.109  -0.156  -0.148  -0.195  -0.244  -0.239
117   D        -0.815  -0.770  -0.831  -0.688  -0.619  -0.711  -0.831  -0.774  -0.836
118   I         0.154   0.187   0.053   0.014   0.072  -0.156   0.050   0.102  -0.117
119   R        -0.815  -0.806  -0.821  -0.727  -0.710  -0.729  -0.831  -0.820  -0.823
120   L        -0.815  -0.770  -0.831  -1.143  -1.069  -1.156  -0.831  -0.774  -0.836
121   L        -1.518  -1.512  -1.447  -1.572  -1.572  -1.451  -1.272  -1.264  -1.171
122   D        -0.111  -0.106  -0.060  -0.231  -0.220  -0.139  -0.390  -0.381  -0.308
123   F         0.154   0.187   0.053   0.264   0.319   0.068   0.050   0.102  -0.117
124   V        -1.518  -1.512  -1.447  -1.340  -1.329  -1.224  -1.272  -1.264  -1.171
125   V         0.154   0.132   0.040   0.030  -0.000  -0.156   0.050   0.015  -0.140
126   P         1.295   1.297   1.324   1.371   1.375   1.416   1.373   1.374   1.410
127   E        -1.518  -1.512  -1.447  -1.372  -1.369  -1.256  -1.272  -1.264  -1.171
128   E        -1.518  -1.512  -1.447  -1.369  -1.366  -1.253  -1.272  -1.264  -1.171
129   W        -0.815  -0.848  -0.845  -0.579  -0.632  -0.620  -0.831  -0.871  -0.853
130   S        -1.518  -1.512  -1.447  -1.572  -1.552  -1.451  -1.272  -1.264  -1.171
131   A        -1.518  -1.512  -1.447  -1.512  -1.520  -1.392  -1.272  -1.264  -1.171
132   E        -0.815  -0.848  -0.845  -0.742  -0.793  -0.783  -0.831  -0.871  -0.853
133   N         0.154   0.187   0.053   0.214   0.265   0.046   0.050   0.102  -0.117
134   -         0.004  -0.050  -0.033   0.099  -0.001   0.019  -0.195  -0.284  -0.263
135   P         0.154   0.121   0.037   0.202   0.147  -0.004   0.050  -0.002  -0.145
136   L         1.295   1.297   1.324   1.078   1.082   1.131   1.373   1.374   1.410
137   V        -0.111  -0.109  -0.061  -0.420  -0.415  -0.328  -0.390  -0.386  -0.311
138   V        -0.815  -0.770  -0.831  -1.040  -0.954  -1.094  -0.831  -0.774  -0.836
139   E         1.295   1.297   1.324   1.340   1.342   1.386   1.373   1.374   1.410
140   G         1.295   1.297   1.324   1.334   1.335   1.380   1.373   1.374   1.410
141   A         1.295   1.297   1.324   1.377   1.379   1.422   1.373   1.374   1.410
142   G         1.295   1.297   1.324   1.334   1.335   1.380   1.373   1.374   1.410
143   G         1.295   1.297   1.324   1.334   1.335   1.380   1.373   1.374   1.410
144   V         0.154   0.132   0.040  -0.084  -0.120  -0.262   0.050   0.015  -0.140
145   C        -0.815  -0.808  -0.819  -0.501  -0.493  -0.494  -0.831  -0.822  -0.821
146   V         1.295   1.297   1.324   1.303   1.301   1.349   1.373   1.374   1.410
147   P         1.295   1.297   1.324   1.371   1.375   1.416   1.373   1.374   1.410
148   I         1.295   1.297   1.324   1.195   1.205   1.244   1.373   1.374   1.410
149   T        -0.111  -0.106  -0.060  -0.331  -0.328  -0.242  -0.390  -0.381  -0.308
150   R        -0.815  -0.848  -0.845  -0.745  -0.797  -0.780  -0.831  -0.871  -0.853
151   K        -0.111  -0.106  -0.060  -0.331  -0.318  -0.236  -0.390  -0.381  -0.308
152   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
153   E         0.154   0.189   0.050   0.264   0.312   0.120   0.050   0.106  -0.123
154   I         1.295   1.297   1.324   1.195   1.205   1.244   1.373   1.374   1.410
155   T         1.295   1.297   1.324   1.252   1.253   1.300   1.373   1.374   1.410
156   T         1.295   1.297   1.324   1.252   1.253   1.300   1.373   1.374   1.410
157   D         1.295   1.297   1.324   1.414   1.416   1.458   1.373   1.374   1.410
158   L         1.295   1.297   1.324   1.078   1.082   1.131   1.373   1.374   1.410
159   I         1.295   1.297   1.324   1.195   1.205   1.244   1.373   1.374   1.410
160   K        -0.815  -0.808  -0.819  -0.787  -0.772  -0.822  -0.831  -0.822  -0.821
161   H        -0.815  -0.813  -0.822  -0.649  -0.651  -0.675  -0.831  -0.829  -0.824
162   L        -0.815  -0.814  -0.822  -0.884  -0.882  -0.851  -0.831  -0.831  -0.825
163   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
164   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
165   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
166   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
167   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
168   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
169   H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
170   P        -0.815  -0.848  -0.845  -0.750  -0.810  -0.809  -0.831  -0.871  -0.853
171   V        -0.815  -0.806  -0.821  -0.912  -0.901  -0.904  -0.831  -0.820  -0.823
172   Y        -0.815  -0.848  -0.845  -0.680  -0.730  -0.712  -0.831  -0.871  -0.853
173   V         0.154   0.121   0.037   0.101   0.042  -0.116   0.050  -0.002  -0.145
174   V        -0.111  -0.106  -0.060  -0.420  -0.404  -0.322  -0.390  -0.381  -0.308
175   V        -0.111  -0.106  -0.060  -0.506  -0.490  -0.403  -0.390  -0.381  -0.308
176   V         1.295   1.297   1.324   1.303   1.301   1.349   1.373   1.374   1.410
177   A         1.295   1.297   1.324   1.377   1.379   1.422   1.373   1.374   1.410
178   R         0.154   0.121   0.037   0.367   0.315   0.165   0.050  -0.002  -0.145
179   S         1.295   1.297   1.324   1.359   1.365   1.404   1.373   1.374   1.410
180   G         1.295   1.297   1.324   1.334   1.335   1.380   1.373   1.374   1.410
181   L         1.295   1.297   1.324   1.078   1.082   1.131   1.373   1.374   1.410
182   G         1.295   1.297   1.324   1.334   1.335   1.380   1.373   1.374   1.410
183   T         1.295   1.297   1.324   1.252   1.253   1.300   1.373   1.374   1.410
184   L        -0.111  -0.106  -0.060  -0.590  -0.579  -0.494  -0.390  -0.381  -0.308
185   N         1.295   1.297   1.324   1.365   1.367   1.410   1.373   1.374   1.410
186   H         1.295   1.297   1.324   1.524   1.525   1.564   1.373   1.374   1.410
187   T         1.295   1.297   1.324   1.252   1.253   1.300   1.373   1.374   1.410
188   L         0.154   0.121   0.037   0.014  -0.031  -0.126   0.050  -0.002  -0.145
189   L         1.295   1.297   1.324   1.078   1.082   1.131   1.373   1.374   1.410
190   T        -0.111  -0.106  -0.060  -0.335  -0.330  -0.246  -0.390  -0.381  -0.308
191   W        -1.518  -1.512  -1.447  -1.594  -1.567  -1.472  -1.272  -1.264  -1.171
192   N         0.154   0.132   0.040   0.192   0.156   0.003   0.050   0.015  -0.140
193   H         1.295   1.297   1.324   1.524   1.525   1.564   1.373   1.374   1.410
194   L         1.295   1.297   1.324   1.078   1.082   1.131   1.373   1.374   1.410
195   C        -1.518  -1.512  -1.447  -1.228  -1.220  -1.116  -1.272  -1.264  -1.171
196   D        -0.815  -0.806  -0.821  -0.766  -0.753  -0.773  -0.831  -0.820  -0.823
197   N        -0.815  -0.848  -0.845  -0.599  -0.654  -0.655  -0.831  -0.871  -0.853
198   G         0.154   0.189   0.050   0.186   0.238   0.015   0.050   0.106  -0.123
199   L        -0.111  -0.106  -0.060  -0.590  -0.579  -0.494  -0.390  -0.381  -0.308
200   R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
201   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
202   H        -0.815  -0.813  -0.822  -0.649  -0.651  -0.675  -0.831  -0.829  -0.824
203   L        -1.518  -1.512  -1.447  -1.634  -1.620  -1.511  -1.272  -1.264  -1.171
204   F        -1.518  -1.512  -1.447  -1.576  -1.555  -1.454  -1.272  -1.264  -1.171
205   G         0.154   0.187   0.053   0.258   0.302   0.119   0.050   0.102  -0.117
206   V        -0.815  -0.813  -0.822  -0.798  -0.788  -0.798  -0.831  -0.829  -0.824
207   I        -0.111  -0.106  -0.060  -0.420  -0.412  -0.328  -0.390  -0.381  -0.308
208   L         0.154   0.187   0.053   0.014   0.058  -0.104   0.050   0.102  -0.117
209   N         1.295   1.297   1.324   1.365   1.367   1.410   1.373   1.374   1.410
210   G         1.295   1.297   1.324   1.334   1.335   1.380   1.373   1.374   1.410
211   E        -0.815  -0.806  -0.821  -0.790  -0.778  -0.802  -0.831  -0.820  -0.823
212   P        -0.815  -0.806  -0.821  -1.057  -1.031  -1.068  -0.831  -0.820  -0.823
213   N         1.295   1.297   1.324   1.365   1.367   1.410   1.373   1.374   1.410
214   E        -1.518  -1.512  -1.447  -1.505  -1.496  -1.385  -1.272  -1.264  -1.171
215   G        -0.815  -0.848  -0.845  -0.827  -0.891  -0.903  -0.831  -0.871  -0.853
216   N         1.295   1.297   1.324   1.365   1.367   1.410   1.373   1.374   1.410
217   V         0.154   0.132   0.040   0.208   0.169   0.007   0.050   0.015  -0.140
218   Q        -1.518  -1.512  -1.447  -1.372  -1.363  -1.256  -1.272  -1.264  -1.171
219   A         0.154   0.121   0.037   0.192   0.135  -0.022   0.050  -0.002  -0.145
220   L        -0.111  -0.106  -0.060  -0.590  -0.579  -0.494  -0.390  -0.381  -0.308
221   K        -0.111  -0.109  -0.061  -0.146  -0.142  -0.062  -0.390  -0.386  -0.311
222   K        -1.518  -1.512  -1.447  -1.282  -1.282  -1.168  -1.272  -1.264  -1.171
223   F         1.295   1.297   1.324   1.469   1.471   1.511   1.373   1.374   1.410
224   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
225   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
226   G         0.154   0.189   0.050   0.202   0.253   0.037   0.050   0.106  -0.123
227   V        -0.111  -0.106  -0.060  -0.420  -0.404  -0.322  -0.390  -0.381  -0.308
228   N        -0.815  -0.770  -0.831  -0.782  -0.710  -0.809  -0.831  -0.774  -0.836
229   I         1.295   1.297   1.324   1.195   1.205   1.244   1.373   1.374   1.410
230   M        -0.815  -0.848  -0.845  -0.957  -1.007  -0.990  -0.831  -0.871  -0.853
231   A        -0.815  -0.813  -0.822  -0.898  -0.890  -0.928  -0.831  -0.829  -0.824
232   Q        -0.815  -0.814  -0.822  -0.680  -0.685  -0.707  -0.831  -0.831  -0.825
233   V        -0.111  -0.109  -0.061  -0.420  -0.415  -0.328  -0.390  -0.386  -0.311
234   A        -0.815  -0.848  -0.845  -0.785  -0.842  -0.837  -0.831  -0.871  -0.853
235   Q        -1.518  -1.512  -1.447  -1.222  -1.212  -1.110  -1.272  -1.264  -1.171
236   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
237   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
238   C        -0.815  -0.770  -0.831  -0.685  -0.598  -0.758  -0.831  -0.774  -0.836
239   T        -1.518  -1.512  -1.447  -1.508  -1.507  -1.388  -1.272  -1.264  -1.171
240   T        -0.815  -0.770  -0.831  -1.011  -0.932  -1.047  -0.831  -0.774  -0.836
241   A        -0.815  -0.806  -0.821  -0.827  -0.814  -0.843  -0.831  -0.820  -0.823
242   H        -1.518  -1.512  -1.447  -1.443  -1.419  -1.325  -1.272  -1.264  -1.171
243   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
244   Q        -0.815  -0.848  -0.845  -0.996  -1.049  -1.038  -0.831  -0.871  -0.853
245   D        -0.815  -0.814  -0.822  -0.753  -0.756  -0.772  -0.831  -0.831  -0.825
246   M        -0.815  -0.848  -0.845  -0.637  -0.680  -0.656  -0.831  -0.871  -0.853
247   E        -0.815  -0.848  -0.845  -1.040  -1.088  -1.052  -0.831  -0.871  -0.853
248   L         0.154   0.187   0.053  -0.026   0.021  -0.159   0.050   0.102  -0.117
249   H        -1.518  -1.512  -1.447  -1.353  -1.341  -1.237  -1.272  -1.264  -1.171
250   E        -1.518  -1.512  -1.447  -1.484  -1.475  -1.365  -1.272  -1.264  -1.171
251   L        -0.815  -0.848  -0.845  -0.863  -0.921  -0.910  -0.831  -0.871  -0.853
252   P         1.295   1.297   1.324   1.371   1.375   1.416   1.373   1.374   1.410
253   S        -0.815  -0.813  -0.822  -0.769  -0.765  -0.777  -0.831  -0.829  -0.824
254   V        -0.111  -0.106  -0.060  -0.506  -0.490  -0.403  -0.390  -0.381  -0.308
255   E        -0.815  -0.814  -0.822  -0.716  -0.717  -0.715  -0.831  -0.831  -0.825
256   S        -0.815  -0.813  -0.822  -0.740  -0.740  -0.744  -0.831  -0.829  -0.824
257   L         0.154   0.187   0.053  -0.121  -0.065  -0.290   0.050   0.102  -0.117
258   M         0.004   0.028  -0.008   0.255   0.297   0.228  -0.195  -0.153  -0.220
259   T        -0.934  -0.929  -0.872  -1.044  -1.021  -0.936  -0.978  -0.970  -0.884
260   Q        -0.934  -0.929  -0.872  -0.880  -0.878  -0.776  -0.978  -0.970  -0.884
261   Q        -0.815  -0.808  -0.819  -0.737  -0.726  -0.739  -0.831  -0.822  -0.821
262   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
263   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
264   E        -0.815  -0.806  -0.821  -0.701  -0.696  -0.700  -0.831  -0.820  -0.823
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P53630
Output conservation file - output/P53630
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
