1     M         0.698   0.708   0.736   0.946   0.956   0.964   0.726   0.740   0.777
2     S         0.698   0.708   0.736   0.848   0.861   0.884   0.726   0.740   0.777
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     E        -1.518  -1.469  -1.486  -1.648  -1.573  -1.560  -1.552  -1.487  -1.486
5     E         0.698   0.708   0.736   0.507   0.525   0.603   0.726   0.740   0.777
6     Q        -0.919  -0.874  -0.675  -0.946  -0.881  -0.592  -1.308  -1.239  -0.931
7     D         0.698   0.708   0.736   0.678   0.697   0.743   0.726   0.740   0.777
8     P         0.698   0.708   0.736   0.826   0.838   0.866   0.726   0.740   0.777
9     L         0.698   0.708   0.736   0.512   0.528   0.607   0.726   0.740   0.777
10    L         0.698   0.708   0.736   0.512   0.528   0.607   0.726   0.740   0.777
11    A        -1.325  -1.200  -1.482  -1.206  -1.038  -1.421  -1.308  -1.150  -1.481
12    G        -0.353  -0.314  -0.648  -0.342  -0.286  -0.837  -0.404  -0.350  -0.887
13    L        -0.353  -0.328  -0.650  -0.417  -0.384  -0.780  -0.404  -0.371  -0.890
14    G        -1.325  -1.274  -1.481  -1.117  -1.050  -1.529  -1.308  -1.241  -1.479
15    E        -1.661  -1.673  -1.494  -1.929  -1.917  -1.576  -1.760  -1.752  -1.494
16    T        -2.942  -2.879  -2.539  -2.814  -2.760  -2.253  -2.438  -2.363  -1.956
17    S        -3.056  -2.963  -2.539  -2.911  -2.803  -2.208  -2.529  -2.427  -1.957
18    G        -1.762  -1.736  -1.494  -1.803  -1.764  -1.386  -1.878  -1.831  -1.494
19    D        -1.762  -1.736  -1.494  -1.791  -1.753  -1.377  -1.878  -1.831  -1.494
20    N        -1.518  -1.409  -1.488  -1.393  -1.233  -1.476  -1.552  -1.412  -1.487
21    H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
22    T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
23    Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
24    Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
25    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
26    H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
27    E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
28    Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
29    Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
30    P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
31    E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
32    Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
33    P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
34    Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
35    E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
36    T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
37    E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
38    E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
39    H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
40    H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
41    E        -1.518  -1.462  -1.486  -1.609  -1.520  -1.619  -1.552  -1.481  -1.486
42    E        -1.518  -1.462  -1.486  -1.454  -1.370  -1.520  -1.552  -1.481  -1.486
43    E        -0.469  -0.493  -0.656  -0.610  -0.635  -0.845  -0.576  -0.615  -0.900
44    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
45    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
46    P        -1.661  -1.586  -1.495  -1.742  -1.630  -1.466  -1.760  -1.657  -1.495
47    S        -1.325  -1.385  -1.484  -1.361  -1.450  -1.535  -1.308  -1.385  -1.483
48    R        -1.325  -1.252  -1.478  -1.079  -0.983  -1.390  -1.308  -1.215  -1.476
49    V        -2.280  -2.187  -2.075  -2.230  -2.141  -1.964  -2.097  -2.007  -1.777
50    D         0.698   0.708   0.736   0.676   0.696   0.742   0.726   0.740   0.777
51    P        -1.018  -1.291  -1.470  -0.610  -0.968  -1.269  -0.927  -1.263  -1.467
52    E         0.698   0.708   0.736   0.534   0.559   0.625   0.726   0.740   0.777
53    Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
54    E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
55    A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
56    H        -1.806  -1.591  -2.055  -1.462  -1.201  -1.761  -1.562  -1.324  -1.759
57    N        -1.806  -1.987  -2.063  -1.628  -1.874  -1.915  -1.562  -1.759  -1.766
58    K        -2.131  -2.232  -2.072  -2.027  -2.108  -1.851  -1.944  -2.011  -1.774
59    A         0.698   0.708   0.736   0.684   0.704   0.748   0.726   0.740   0.777
60    L        -1.018  -0.902  -1.454  -1.005  -0.868  -1.557  -0.927  -0.785  -1.448
61    N        -3.344  -3.227  -2.904  -3.225  -3.098  -2.637  -2.580  -2.466  -2.067
62    Q        -2.383  -2.282  -2.078  -2.191  -2.083  -1.725  -2.198  -2.089  -1.780
63    F        -0.181  -0.319  -0.629   0.175   0.010  -0.480  -0.164  -0.357  -0.855
64    K         0.698   0.708   0.736   0.634   0.651   0.707   0.726   0.740   0.777
65    R        -2.940  -2.950  -2.534  -2.958  -2.943  -2.340  -2.452  -2.418  -1.953
66    K        -1.018  -1.084  -1.460  -0.832  -0.913  -1.432  -0.927  -1.014  -1.455
67    L         0.698   0.708   0.736   0.472   0.482   0.575   0.726   0.740   0.777
68    L        -2.383  -2.282  -2.072  -2.560  -2.446  -2.070  -2.198  -2.086  -1.775
69    E        -0.181  -0.319  -0.629  -0.191  -0.347  -0.752  -0.164  -0.357  -0.855
70    H        -0.181  -0.343  -0.632   0.319   0.103  -0.429  -0.164  -0.393  -0.859
71    R         0.698   0.708   0.736   0.664   0.681   0.732   0.726   0.740   0.777
72    R        -1.826  -1.694  -1.490  -2.232  -2.026  -1.688  -1.944  -1.781  -1.490
73    Y        -0.919  -0.866  -0.674  -0.746  -0.666  -0.424  -1.308  -1.225  -0.930
74    D        -0.614  -0.669  -0.667  -0.756  -0.863  -0.923  -0.800  -0.894  -0.918
75    D        -2.230  -2.226  -2.074  -2.233  -2.208  -1.933  -2.071  -2.039  -1.776
76    Q        -2.383  -2.187  -2.071  -2.344  -2.074  -1.846  -2.198  -1.982  -1.773
77    L         0.698   0.708   0.736   0.472   0.482   0.575   0.726   0.740   0.777
78    K         0.698   0.708   0.736   0.634   0.651   0.707   0.726   0.740   0.777
79    Q        -2.230  -2.199  -2.071  -2.105  -2.057  -1.890  -2.071  -2.020  -1.774
80    R        -0.845  -0.750  -0.666  -1.308  -1.152  -0.980  -1.181  -1.027  -0.916
81    R         0.698   0.708   0.736   0.664   0.681   0.732   0.726   0.740   0.777
82    Q        -2.131  -2.096  -2.069  -2.154  -2.097  -1.997  -1.944  -1.884  -1.772
83    N        -2.940  -2.878  -2.533  -2.789  -2.746  -2.241  -2.452  -2.370  -1.953
84    I        -1.018  -1.291  -1.470  -0.894  -1.273  -1.575  -0.927  -1.263  -1.467
85    R        -0.181  -0.343  -0.632  -0.103  -0.317  -0.802  -0.164  -0.393  -0.859
86    D        -1.018  -1.106  -1.463  -0.834  -0.969  -1.510  -0.927  -1.043  -1.458
87    L         0.698   0.708   0.736   0.472   0.482   0.575   0.726   0.740   0.777
88    E        -2.131  -2.232  -2.072  -2.157  -2.253  -1.973  -1.944  -2.011  -1.774
89    K        -1.806  -1.596  -2.047  -1.588  -1.319  -1.958  -1.562  -1.330  -1.752
90    L        -2.940  -2.784  -2.528  -3.186  -2.966  -2.585  -2.452  -2.308  -1.949
91    Y        -0.181  -0.120  -0.623   0.239   0.303  -0.451  -0.164  -0.084  -0.845
92    D        -0.614  -0.496  -0.657  -0.756  -0.563  -0.899  -0.800  -0.620  -0.901
93    K        -1.018  -1.106  -1.463  -0.841  -0.954  -1.457  -0.927  -1.043  -1.458
94    T         0.698   0.708   0.736   0.805   0.827   0.848   0.726   0.740   0.777
95    E         0.698   0.708   0.736   0.534   0.559   0.625   0.726   0.740   0.777
96    N        -2.131  -2.201  -2.071  -1.888  -2.050  -1.885  -1.944  -2.007  -1.774
97    D        -0.181  -0.343  -0.632  -0.061  -0.258  -0.678  -0.164  -0.393  -0.859
98    I         0.698   0.708   0.736   0.618   0.640   0.694   0.726   0.740   0.777
99    K         0.698   0.708   0.736   0.634   0.651   0.707   0.726   0.740   0.777
100   A        -0.181  -0.319  -0.629  -0.053  -0.219  -0.685  -0.164  -0.357  -0.855
101   L         0.698   0.708   0.736   0.472   0.482   0.575   0.726   0.740   0.777
102   Q         0.698   0.708   0.736   0.922   0.929   0.944   0.726   0.740   0.777
103   S         0.698   0.708   0.736   0.843   0.852   0.880   0.726   0.740   0.777
104   I        -0.845  -0.750  -0.666  -1.066  -0.901  -0.807  -1.181  -1.027  -0.916
105   G         0.698   0.708   0.736   0.644   0.659   0.716   0.726   0.740   0.777
106   Q         0.698   0.708   0.736   0.922   0.929   0.944   0.726   0.740   0.777
107   L        -0.919  -0.866  -0.674  -1.461  -1.360  -1.012  -1.308  -1.225  -0.930
108   I         0.698   0.708   0.736   0.618   0.640   0.694   0.726   0.740   0.777
109   G         0.698   0.708   0.736   0.644   0.659   0.716   0.726   0.740   0.777
110   E         0.698   0.708   0.736   0.534   0.559   0.625   0.726   0.740   0.777
111   V         0.698   0.708   0.736   0.770   0.773   0.819   0.726   0.740   0.777
112   M        -0.845  -0.750  -0.666  -1.150  -1.017  -0.819  -1.181  -1.027  -0.916
113   K         0.698   0.708   0.736   0.634   0.651   0.707   0.726   0.740   0.777
114   E        -0.845  -0.750  -0.666  -0.974  -0.793  -0.750  -1.181  -1.027  -0.916
115   L         0.698   0.708   0.736   0.472   0.482   0.575   0.726   0.740   0.777
116   S        -0.845  -0.750  -0.666  -1.035  -0.881  -0.751  -1.181  -1.027  -0.916
117   E        -1.574  -1.633  -1.486  -1.832  -1.877  -1.584  -1.690  -1.726  -1.486
118   E         0.698   0.708   0.736   0.534   0.559   0.625   0.726   0.740   0.777
119   K        -0.845  -0.750  -0.666  -1.152  -0.981  -0.869  -1.181  -1.027  -0.916
120   Y        -0.919  -0.859  -0.673  -0.896  -0.809  -0.550  -1.308  -1.214  -0.929
121   I         0.698   0.708   0.736   0.618   0.640   0.694   0.726   0.740   0.777
122   V         0.698   0.708   0.736   0.770   0.773   0.819   0.726   0.740   0.777
123   K         0.698   0.708   0.736   0.634   0.651   0.707   0.726   0.740   0.777
124   A        -0.181  -0.058  -0.617  -0.059   0.093  -0.683  -0.164  -0.003  -0.836
125   S         0.698   0.708   0.736   0.843   0.852   0.880   0.726   0.740   0.777
126   S        -0.181  -0.120  -0.623   0.112   0.178  -0.543  -0.164  -0.084  -0.845
127   G         0.698   0.708   0.736   0.644   0.659   0.716   0.726   0.740   0.777
128   P         0.698   0.708   0.736   0.838   0.853   0.875   0.726   0.740   0.777
129   R         0.698   0.708   0.736   0.664   0.681   0.732   0.726   0.740   0.777
130   Y         0.698   0.708   0.736   0.971   0.976   0.985   0.726   0.740   0.777
131   I        -0.614  -0.755  -0.668  -0.730  -0.971  -0.828  -0.800  -1.035  -0.921
132   V         0.698   0.708   0.736   0.770   0.773   0.819   0.726   0.740   0.777
133   G         0.698   0.708   0.736   0.644   0.659   0.716   0.726   0.740   0.777
134   V        -0.845  -0.750  -0.666  -0.712  -0.552  -0.522  -1.181  -1.027  -0.916
135   R         0.698   0.708   0.736   0.664   0.681   0.732   0.726   0.740   0.777
136   N        -0.614  -0.669  -0.667  -0.447  -0.547  -0.613  -0.800  -0.894  -0.918
137   S        -2.131  -2.232  -2.072  -1.855  -1.992  -1.820  -1.944  -2.011  -1.774
138   V        -0.845  -0.735  -0.661  -1.066  -0.873  -0.797  -1.181  -1.003  -0.909
139   D        -0.845  -0.735  -0.661  -1.147  -0.948  -0.856  -1.181  -1.003  -0.909
140   R        -1.574  -1.603  -1.485  -1.736  -1.730  -1.495  -1.690  -1.683  -1.484
141   S        -1.574  -1.611  -1.484  -1.691  -1.696  -1.541  -1.690  -1.689  -1.484
142   K        -1.806  -1.720  -2.055  -1.467  -1.364  -1.731  -1.562  -1.477  -1.759
143   L         0.698   0.708   0.736   0.472   0.482   0.575   0.726   0.740   0.777
144   K        -1.018  -1.095  -1.463  -0.898  -1.007  -1.608  -0.927  -1.026  -1.459
145   K        -1.826  -1.694  -1.490  -1.867  -1.651  -1.367  -1.944  -1.781  -1.490
146   G         0.698   0.708   0.736   0.644   0.659   0.716   0.726   0.740   0.777
147   V        -0.181  -0.343  -0.632   0.027  -0.189  -0.647  -0.164  -0.393  -0.859
148   R         0.698   0.708   0.736   0.664   0.681   0.732   0.726   0.740   0.777
149   V         0.698   0.708   0.736   0.770   0.773   0.819   0.726   0.740   0.777
150   T        -1.574  -1.620  -1.486  -1.527  -1.568  -1.407  -1.690  -1.701  -1.485
151   L         0.698   0.708   0.736   0.472   0.482   0.575   0.726   0.740   0.777
152   D         0.698   0.708   0.736   0.670   0.687   0.737   0.726   0.740   0.777
153   I        -0.845  -0.750  -0.666  -0.909  -0.732  -0.690  -1.181  -1.027  -0.916
154   T         0.698   0.708   0.736   0.805   0.827   0.848   0.726   0.740   0.777
155   T         0.698   0.708   0.736   0.805   0.827   0.848   0.726   0.740   0.777
156   L         0.698   0.708   0.736   0.472   0.482   0.575   0.726   0.740   0.777
157   T         0.698   0.708   0.736   0.805   0.827   0.848   0.726   0.740   0.777
158   I         0.698   0.708   0.736   0.618   0.640   0.694   0.726   0.740   0.777
159   M         0.698   0.708   0.736   0.946   0.956   0.964   0.726   0.740   0.777
160   R         0.698   0.708   0.736   0.664   0.681   0.732   0.726   0.740   0.777
161   I        -0.181  -0.343  -0.632  -0.103  -0.293  -0.685  -0.164  -0.393  -0.859
162   L         0.698   0.708   0.736   0.472   0.482   0.575   0.726   0.740   0.777
163   P         0.698   0.708   0.736   0.838   0.853   0.875   0.726   0.740   0.777
164   R         0.698   0.708   0.736   0.664   0.681   0.732   0.726   0.740   0.777
165   E         0.698   0.708   0.736   0.534   0.559   0.625   0.726   0.740   0.777
166   T        -0.845  -0.750  -0.666  -0.968  -0.815  -0.707  -1.181  -1.027  -0.916
167   D         0.698   0.708   0.736   0.670   0.687   0.737   0.726   0.740   0.777
168   P         0.698   0.708   0.736   0.838   0.853   0.875   0.726   0.740   0.777
169   L         0.698   0.708   0.736   0.472   0.482   0.575   0.726   0.740   0.777
170   V         0.698   0.708   0.736   0.770   0.773   0.819   0.726   0.740   0.777
171   Y         0.698   0.708   0.736   0.971   0.976   0.985   0.726   0.740   0.777
172   N         0.698   0.708   0.736   0.887   0.902   0.916   0.726   0.740   0.777
173   M         0.698   0.708   0.736   0.946   0.956   0.964   0.726   0.740   0.777
174   T        -0.614  -0.755  -0.668  -0.526  -0.764  -0.668  -0.800  -1.035  -0.921
175   S        -2.131  -2.252  -2.070  -1.967  -2.174  -1.992  -1.944  -2.033  -1.772
176   F        -0.614  -0.755  -0.668  -0.536  -0.819  -0.776  -0.800  -1.035  -0.921
177   E        -0.614  -0.755  -0.668  -0.845  -1.086  -0.940  -0.800  -1.035  -0.921
178   Q        -0.845  -0.750  -0.666  -0.848  -0.696  -0.601  -1.181  -1.027  -0.916
179   G         0.698   0.708   0.736   0.644   0.659   0.716   0.726   0.740   0.777
180   E        -1.018  -1.291  -1.470  -0.940  -1.291  -1.526  -0.927  -1.263  -1.467
181   I        -1.018  -1.117  -1.466  -0.914  -1.050  -1.623  -0.927  -1.055  -1.462
182   T        -0.614  -0.530  -0.660  -0.502  -0.381  -0.648  -0.800  -0.674  -0.906
183   F         0.698   0.708   0.736   0.895   0.912   0.922   0.726   0.740   0.777
184   D        -3.344  -3.303  -2.908  -3.103  -3.080  -2.558  -2.580  -2.517  -2.069
185   G         0.698   0.708   0.736   0.644   0.659   0.716   0.726   0.740   0.777
186   I        -0.181  -0.319  -0.629  -0.130  -0.299  -0.766  -0.164  -0.357  -0.855
187   G         0.698   0.708   0.736   0.644   0.659   0.716   0.726   0.740   0.777
188   G         0.698   0.708   0.736   0.644   0.659   0.716   0.726   0.740   0.777
189   L         0.698   0.708   0.736   0.472   0.482   0.575   0.726   0.740   0.777
190   T        -0.845  -0.867  -0.675  -0.894  -0.935  -0.652  -1.181  -1.227  -0.931
191   E        -0.845  -0.812  -0.674  -1.250  -1.190  -0.947  -1.181  -1.132  -0.930
192   Q         0.698   0.708   0.736   0.922   0.929   0.944   0.726   0.740   0.777
193   I         0.698   0.708   0.736   0.618   0.640   0.694   0.726   0.740   0.777
194   R         0.698   0.708   0.736   0.664   0.681   0.732   0.726   0.740   0.777
195   E         0.698   0.708   0.736   0.534   0.559   0.625   0.726   0.740   0.777
196   L         0.698   0.708   0.736   0.472   0.482   0.575   0.726   0.740   0.777
197   R         0.698   0.708   0.736   0.664   0.681   0.732   0.726   0.740   0.777
198   E         0.698   0.708   0.736   0.534   0.559   0.625   0.726   0.740   0.777
199   V         0.698   0.708   0.736   0.770   0.773   0.819   0.726   0.740   0.777
200   I         0.698   0.708   0.736   0.618   0.640   0.694   0.726   0.740   0.777
201   E         0.698   0.708   0.736   0.534   0.559   0.625   0.726   0.740   0.777
202   L         0.698   0.708   0.736   0.472   0.482   0.575   0.726   0.740   0.777
203   P         0.698   0.708   0.736   0.838   0.853   0.875   0.726   0.740   0.777
204   L         0.698   0.708   0.736   0.472   0.482   0.575   0.726   0.740   0.777
205   K         0.698   0.708   0.736   0.634   0.651   0.707   0.726   0.740   0.777
206   N         0.698   0.708   0.736   0.887   0.902   0.916   0.726   0.740   0.777
207   P         0.698   0.708   0.736   0.838   0.853   0.875   0.726   0.740   0.777
208   E         0.698   0.708   0.736   0.534   0.559   0.625   0.726   0.740   0.777
209   I        -0.845  -0.750  -0.666  -1.333  -1.172  -1.006  -1.181  -1.027  -0.916
210   F         0.698   0.708   0.736   0.895   0.912   0.922   0.726   0.740   0.777
211   Q        -2.383  -2.187  -2.071  -2.500  -2.251  -2.035  -2.198  -1.982  -1.773
212   R         0.698   0.708   0.736   0.664   0.681   0.732   0.726   0.740   0.777
213   V         0.698   0.708   0.736   0.770   0.773   0.819   0.726   0.740   0.777
214   G         0.698   0.708   0.736   0.644   0.659   0.716   0.726   0.740   0.777
215   I         0.698   0.708   0.736   0.618   0.640   0.694   0.726   0.740   0.777
216   K         0.698   0.708   0.736   0.634   0.651   0.707   0.726   0.740   0.777
217   P        -0.181  -0.054  -0.619   0.100   0.248  -0.559  -0.164   0.003  -0.838
218   P         0.698   0.708   0.736   0.838   0.853   0.875   0.726   0.740   0.777
219   K         0.698   0.708   0.736   0.634   0.651   0.707   0.726   0.740   0.777
220   G         0.698   0.708   0.736   0.644   0.659   0.716   0.726   0.740   0.777
221   V         0.698   0.708   0.736   0.770   0.773   0.819   0.726   0.740   0.777
222   L         0.698   0.708   0.736   0.472   0.482   0.575   0.726   0.740   0.777
223   L         0.698   0.708   0.736   0.472   0.482   0.575   0.726   0.740   0.777
224   Y         0.698   0.708   0.736   0.971   0.976   0.985   0.726   0.740   0.777
225   G         0.698   0.708   0.736   0.644   0.659   0.716   0.726   0.740   0.777
226   P         0.698   0.708   0.736   0.838   0.853   0.875   0.726   0.740   0.777
227   P         0.698   0.708   0.736   0.838   0.853   0.875   0.726   0.740   0.777
228   G         0.698   0.708   0.736   0.644   0.659   0.716   0.726   0.740   0.777
229   T         0.698   0.708   0.736   0.805   0.827   0.848   0.726   0.740   0.777
230   G         0.698   0.708   0.736   0.644   0.659   0.716   0.726   0.740   0.777
231   K         0.698   0.708   0.736   0.634   0.651   0.707   0.726   0.740   0.777
232   T         0.698   0.708   0.736   0.805   0.827   0.848   0.726   0.740   0.777
233   L         0.698   0.708   0.736   0.472   0.482   0.575   0.726   0.740   0.777
234   L         0.698   0.708   0.736   0.472   0.482   0.575   0.726   0.740   0.777
235   A         0.698   0.708   0.736   0.684   0.704   0.748   0.726   0.740   0.777
236   K        -0.614  -0.755  -0.668  -0.749  -1.004  -0.877  -0.800  -1.035  -0.921
237   A         0.698   0.708   0.736   0.684   0.704   0.748   0.726   0.740   0.777
238   V         0.698   0.708   0.736   0.770   0.773   0.819   0.726   0.740   0.777
239   A         0.698   0.708   0.736   0.684   0.704   0.748   0.726   0.740   0.777
240   A        -0.181  -0.343  -0.632  -0.053  -0.252  -0.689  -0.164  -0.393  -0.859
241   T        -0.614  -0.755  -0.668  -0.526  -0.764  -0.668  -0.800  -1.035  -0.921
242   I        -0.614  -0.755  -0.668  -0.827  -1.109  -0.995  -0.800  -1.035  -0.921
243   G        -0.181  -0.343  -0.632  -0.138  -0.358  -0.863  -0.164  -0.393  -0.859
244   A        -1.018  -1.291  -1.470  -0.794  -1.155  -1.442  -0.927  -1.263  -1.467
245   N         0.698   0.708   0.736   0.887   0.902   0.916   0.726   0.740   0.777
246   F         0.698   0.708   0.736   0.895   0.912   0.922   0.726   0.740   0.777
247   I        -0.614  -0.755  -0.668  -0.827  -1.109  -0.995  -0.800  -1.035  -0.921
248   F        -0.614  -0.755  -0.668  -0.505  -0.778  -0.723  -0.800  -1.035  -0.921
249   S        -0.614  -0.755  -0.668  -0.513  -0.777  -0.684  -0.800  -1.035  -0.921
250   P        -0.614  -0.755  -0.668  -0.518  -0.776  -0.687  -0.800  -1.035  -0.921
251   A        -0.614  -0.755  -0.668  -0.642  -0.874  -0.745  -0.800  -1.035  -0.921
252   S         0.698   0.708   0.736   0.843   0.852   0.880   0.726   0.740   0.777
253   G        -0.845  -0.750  -0.666  -1.129  -0.956  -0.850  -1.181  -1.027  -0.916
254   I         0.698   0.708   0.736   0.618   0.640   0.694   0.726   0.740   0.777
255   V         0.698   0.708   0.736   0.770   0.773   0.819   0.726   0.740   0.777
256   D         0.698   0.708   0.736   0.670   0.687   0.737   0.726   0.740   0.777
257   K         0.698   0.708   0.736   0.634   0.651   0.707   0.726   0.740   0.777
258   Y         0.698   0.708   0.736   0.971   0.976   0.985   0.726   0.740   0.777
259   I         0.698   0.708   0.736   0.618   0.640   0.694   0.726   0.740   0.777
260   G         0.698   0.708   0.736   0.644   0.659   0.716   0.726   0.740   0.777
261   E         0.698   0.708   0.736   0.534   0.559   0.625   0.726   0.740   0.777
262   S         0.698   0.708   0.736   0.843   0.852   0.880   0.726   0.740   0.777
263   A         0.698   0.708   0.736   0.684   0.704   0.748   0.726   0.740   0.777
264   R         0.698   0.708   0.736   0.664   0.681   0.732   0.726   0.740   0.777
265   I        -0.919  -0.876  -0.675  -1.461  -1.393  -1.016  -1.308  -1.242  -0.931
266   I         0.698   0.708   0.736   0.618   0.640   0.694   0.726   0.740   0.777
267   R         0.698   0.708   0.736   0.664   0.681   0.732   0.726   0.740   0.777
268   E         0.698   0.708   0.736   0.534   0.559   0.625   0.726   0.740   0.777
269   M         0.698   0.708   0.736   0.946   0.956   0.964   0.726   0.740   0.777
270   F         0.698   0.708   0.736   0.895   0.912   0.922   0.726   0.740   0.777
271   A        -0.845  -0.867  -0.675  -1.129  -1.192  -0.871  -1.181  -1.227  -0.931
272   Y         0.698   0.708   0.736   0.971   0.976   0.985   0.726   0.740   0.777
273   A         0.698   0.708   0.736   0.684   0.704   0.748   0.726   0.740   0.777
274   K         0.698   0.708   0.736   0.634   0.651   0.707   0.726   0.740   0.777
275   E         0.698   0.708   0.736   0.534   0.559   0.625   0.726   0.740   0.777
276   H         0.698   0.708   0.736   1.059   1.065   1.057   0.726   0.740   0.777
277   E         0.698   0.708   0.736   0.534   0.559   0.625   0.726   0.740   0.777
278   P         0.698   0.708   0.736   0.838   0.853   0.875   0.726   0.740   0.777
279   C         0.698   0.708   0.736   1.085   1.090   1.078   0.726   0.740   0.777
280   I        -0.181  -0.319  -0.629  -0.130  -0.299  -0.766  -0.164  -0.357  -0.855
281   I         0.698   0.708   0.736   0.618   0.640   0.694   0.726   0.740   0.777
282   F         0.698   0.708   0.736   0.895   0.912   0.922   0.726   0.740   0.777
283   M         0.698   0.708   0.736   0.946   0.956   0.964   0.726   0.740   0.777
284   D         0.698   0.708   0.736   0.670   0.687   0.737   0.726   0.740   0.777
285   E         0.698   0.708   0.736   0.534   0.559   0.625   0.726   0.740   0.777
286   V        -0.845  -0.866  -0.674  -1.066  -1.147  -0.834  -1.181  -1.225  -0.931
287   D         0.698   0.708   0.736   0.670   0.687   0.737   0.726   0.740   0.777
288   A         0.698   0.708   0.736   0.684   0.704   0.748   0.726   0.740   0.777
289   I         0.698   0.708   0.736   0.618   0.640   0.694   0.726   0.740   0.777
290   G         0.698   0.708   0.736   0.644   0.659   0.716   0.726   0.740   0.777
291   G         0.698   0.708   0.736   0.644   0.659   0.716   0.726   0.740   0.777
292   R         0.698   0.708   0.736   0.664   0.681   0.732   0.726   0.740   0.777
293   R         0.698   0.708   0.736   0.664   0.681   0.732   0.726   0.740   0.777
294   F         0.698   0.708   0.736   0.895   0.912   0.922   0.726   0.740   0.777
295   S         0.698   0.708   0.736   0.843   0.852   0.880   0.726   0.740   0.777
296   E         0.698   0.708   0.736   0.534   0.559   0.625   0.726   0.740   0.777
297   G         0.698   0.708   0.736   0.644   0.659   0.716   0.726   0.740   0.777
298   T         0.698   0.708   0.736   0.805   0.827   0.848   0.726   0.740   0.777
299   S         0.698   0.708   0.736   0.843   0.852   0.880   0.726   0.740   0.777
300   A        -0.181  -0.120  -0.623  -0.053   0.025  -0.675  -0.164  -0.084  -0.845
301   D         0.698   0.708   0.736   0.670   0.687   0.737   0.726   0.740   0.777
302   R         0.698   0.708   0.736   0.664   0.681   0.732   0.726   0.740   0.777
303   E         0.698   0.708   0.736   0.534   0.559   0.625   0.726   0.740   0.777
304   I         0.698   0.708   0.736   0.618   0.640   0.694   0.726   0.740   0.777
305   Q         0.698   0.708   0.736   0.922   0.929   0.944   0.726   0.740   0.777
306   R         0.698   0.708   0.736   0.664   0.681   0.732   0.726   0.740   0.777
307   T         0.698   0.708   0.736   0.805   0.827   0.848   0.726   0.740   0.777
308   L         0.698   0.708   0.736   0.472   0.482   0.575   0.726   0.740   0.777
309   M         0.698   0.708   0.736   0.946   0.956   0.964   0.726   0.740   0.777
310   E         0.698   0.708   0.736   0.534   0.559   0.625   0.726   0.740   0.777
311   L         0.698   0.708   0.736   0.472   0.482   0.575   0.726   0.740   0.777
312   L         0.698   0.708   0.736   0.472   0.482   0.575   0.726   0.740   0.777
313   T        -0.845  -0.750  -0.666  -0.866  -0.698  -0.631  -1.181  -1.027  -0.916
314   Q         0.698   0.708   0.736   0.922   0.929   0.944   0.726   0.740   0.777
315   M        -0.181  -0.343  -0.632   0.158  -0.077  -0.672  -0.164  -0.393  -0.859
316   D         0.698   0.708   0.736   0.670   0.687   0.737   0.726   0.740   0.777
317   G         0.698   0.708   0.736   0.644   0.659   0.716   0.726   0.740   0.777
318   F         0.698   0.708   0.736   0.895   0.912   0.922   0.726   0.740   0.777
319   D         0.698   0.708   0.736   0.670   0.687   0.737   0.726   0.740   0.777
320   N        -1.826  -1.694  -1.490  -1.707  -1.502  -1.255  -1.944  -1.781  -1.490
321   L         0.698   0.708   0.736   0.472   0.482   0.575   0.726   0.740   0.777
322   G         0.698   0.708   0.736   0.644   0.659   0.716   0.726   0.740   0.777
323   Q        -0.614  -0.669  -0.667  -0.480  -0.597  -0.702  -0.800  -0.894  -0.918
324   T         0.698   0.708   0.736   0.805   0.827   0.848   0.726   0.740   0.777
325   K         0.698   0.708   0.736   0.634   0.651   0.707   0.726   0.740   0.777
326   I        -0.845  -0.752  -0.670  -1.120  -0.966  -0.830  -1.181  -1.031  -0.923
327   I         0.698   0.708   0.736   0.618   0.640   0.694   0.726   0.740   0.777
328   M         0.698   0.708   0.736   0.946   0.956   0.964   0.726   0.740   0.777
329   A         0.698   0.708   0.736   0.684   0.704   0.748   0.726   0.740   0.777
330   T         0.698   0.708   0.736   0.805   0.827   0.848   0.726   0.740   0.777
331   N         0.698   0.708   0.736   0.887   0.902   0.916   0.726   0.740   0.777
332   R         0.698   0.708   0.736   0.664   0.681   0.732   0.726   0.740   0.777
333   P         0.698   0.708   0.736   0.838   0.853   0.875   0.726   0.740   0.777
334   D         0.698   0.708   0.736   0.670   0.687   0.737   0.726   0.740   0.777
335   T         0.698   0.708   0.736   0.805   0.827   0.848   0.726   0.740   0.777
336   L         0.698   0.708   0.736   0.472   0.482   0.575   0.726   0.740   0.777
337   D         0.698   0.708   0.736   0.670   0.687   0.737   0.726   0.740   0.777
338   P         0.698   0.708   0.736   0.838   0.853   0.875   0.726   0.740   0.777
339   A         0.698   0.708   0.736   0.684   0.704   0.748   0.726   0.740   0.777
340   L         0.698   0.708   0.736   0.472   0.482   0.575   0.726   0.740   0.777
341   L         0.698   0.708   0.736   0.472   0.482   0.575   0.726   0.740   0.777
342   R         0.698   0.708   0.736   0.664   0.681   0.732   0.726   0.740   0.777
343   P        -0.919  -0.876  -0.675  -1.142  -1.070  -0.753  -1.308  -1.242  -0.931
344   G         0.698   0.708   0.736   0.644   0.659   0.716   0.726   0.740   0.777
345   R         0.698   0.708   0.736   0.664   0.681   0.732   0.726   0.740   0.777
346   L         0.698   0.708   0.736   0.472   0.482   0.575   0.726   0.740   0.777
347   D         0.698   0.708   0.736   0.670   0.687   0.737   0.726   0.740   0.777
348   R         0.698   0.708   0.736   0.664   0.681   0.732   0.726   0.740   0.777
349   K         0.698   0.708   0.736   0.634   0.651   0.707   0.726   0.740   0.777
350   V        -0.181  -0.105  -0.620  -0.130  -0.032  -0.750  -0.164  -0.063  -0.839
351   E         0.698   0.708   0.736   0.534   0.559   0.625   0.726   0.740   0.777
352   I         0.698   0.708   0.736   0.618   0.640   0.694   0.726   0.740   0.777
353   P        -1.402  -1.212  -1.464  -1.247  -0.959  -1.376  -1.435  -1.186  -1.459
354   L         0.698   0.708   0.736   0.472   0.482   0.575   0.726   0.740   0.777
355   P         0.698   0.708   0.736   0.838   0.853   0.875   0.726   0.740   0.777
356   N         0.698   0.708   0.736   0.887   0.902   0.916   0.726   0.740   0.777
357   E         0.698   0.708   0.736   0.534   0.559   0.625   0.726   0.740   0.777
358   A        -0.614  -0.755  -0.668  -0.667  -0.911  -0.786  -0.800  -1.035  -0.921
359   G         0.698   0.708   0.736   0.644   0.659   0.716   0.726   0.740   0.777
360   R         0.698   0.708   0.736   0.664   0.681   0.732   0.726   0.740   0.777
361   L        -0.181  -0.319  -0.629  -0.248  -0.417  -0.783  -0.164  -0.357  -0.855
362   E         0.698   0.708   0.736   0.534   0.559   0.625   0.726   0.740   0.777
363   I        -0.181  -0.120  -0.623  -0.130  -0.051  -0.756  -0.164  -0.084  -0.845
364   F        -0.614  -0.755  -0.668  -0.555  -0.853  -0.809  -0.800  -1.035  -0.921
365   K         0.698   0.708   0.736   0.634   0.651   0.707   0.726   0.740   0.777
366   I         0.698   0.708   0.736   0.618   0.640   0.694   0.726   0.740   0.777
367   H         0.698   0.708   0.736   1.059   1.065   1.057   0.726   0.740   0.777
368   T        -1.402  -1.551  -1.485  -1.332  -1.585  -1.579  -1.435  -1.609  -1.485
369   A        -2.131  -2.078  -2.063  -1.949  -1.893  -1.930  -1.944  -1.875  -1.766
370   K        -1.402  -1.388  -1.480  -1.431  -1.450  -1.514  -1.435  -1.437  -1.479
371   V         0.698   0.708   0.736   0.770   0.773   0.819   0.726   0.740   0.777
372   K        -2.787  -2.826  -2.534  -2.616  -2.655  -2.195  -2.325  -2.324  -1.953
373   K        -0.181  -0.343  -0.632  -0.136  -0.349  -0.831  -0.164  -0.393  -0.859
374   T        -2.535  -2.461  -2.524  -2.022  -1.972  -2.172  -2.071  -1.997  -1.946
375   G         0.698   0.708   0.736   0.644   0.659   0.716   0.726   0.740   0.777
376   E        -0.181  -0.343  -0.632  -0.229  -0.431  -0.878  -0.164  -0.393  -0.859
377   F        -0.845  -0.867  -0.675  -0.955  -1.039  -0.758  -1.181  -1.227  -0.931
378   D         0.698   0.708   0.736   0.670   0.687   0.737   0.726   0.740   0.777
379   F        -0.845  -0.867  -0.675  -0.773  -0.822  -0.551  -1.181  -1.227  -0.931
380   E        -0.181  -0.063  -0.619  -0.229  -0.076  -0.856  -0.164  -0.009  -0.838
381   A        -0.181  -0.343  -0.632  -0.053  -0.252  -0.689  -0.164  -0.393  -0.859
382   A        -1.727  -1.746  -1.498  -1.960  -2.029  -1.642  -1.817  -1.835  -1.499
383   V         0.698   0.708   0.736   0.770   0.773   0.819   0.726   0.740   0.777
384   K         0.698   0.708   0.736   0.634   0.651   0.707   0.726   0.740   0.777
385   M        -0.181  -0.319  -0.629   0.158  -0.040  -0.665  -0.164  -0.357  -0.855
386   S        -0.181  -0.319  -0.629   0.100  -0.078  -0.591  -0.164  -0.357  -0.855
387   D         0.698   0.708   0.736   0.670   0.687   0.737   0.726   0.740   0.777
388   G         0.698   0.708   0.736   0.644   0.659   0.716   0.726   0.740   0.777
389   F        -1.018  -1.291  -1.470  -0.631  -1.026  -1.438  -0.927  -1.263  -1.467
390   N         0.698   0.708   0.736   0.887   0.902   0.916   0.726   0.740   0.777
391   G         0.698   0.708   0.736   0.644   0.659   0.716   0.726   0.740   0.777
392   A         0.698   0.708   0.736   0.684   0.704   0.748   0.726   0.740   0.777
393   D         0.698   0.708   0.736   0.670   0.687   0.737   0.726   0.740   0.777
394   I        -0.614  -0.755  -0.668  -0.827  -1.109  -0.995  -0.800  -1.035  -0.921
395   R         0.698   0.708   0.736   0.664   0.681   0.732   0.726   0.740   0.777
396   N         0.698   0.708   0.736   0.887   0.902   0.916   0.726   0.740   0.777
397   C        -0.845  -0.750  -0.666  -0.820  -0.693  -0.556  -1.181  -1.027  -0.916
398   A        -1.727  -1.554  -1.488  -1.859  -1.577  -1.546  -1.817  -1.595  -1.487
399   T         0.698   0.708   0.736   0.805   0.827   0.848   0.726   0.740   0.777
400   E         0.698   0.708   0.736   0.534   0.559   0.625   0.726   0.740   0.777
401   A         0.698   0.708   0.736   0.684   0.704   0.748   0.726   0.740   0.777
402   G         0.698   0.708   0.736   0.644   0.659   0.716   0.726   0.740   0.777
403   F        -0.181  -0.343  -0.632   0.106  -0.121  -0.709  -0.164  -0.393  -0.859
404   F        -0.181  -0.319  -0.629   0.126  -0.055  -0.638  -0.164  -0.357  -0.855
405   A         0.698   0.708   0.736   0.684   0.704   0.748   0.726   0.740   0.777
406   I         0.698   0.708   0.736   0.618   0.640   0.694   0.726   0.740   0.777
407   R        -0.614  -0.755  -0.668  -0.730  -0.990  -0.875  -0.800  -1.035  -0.921
408   D        -0.614  -0.624  -0.663  -0.756  -0.781  -0.914  -0.800  -0.821  -0.912
409   D        -1.018  -1.057  -1.461  -0.818  -0.863  -1.464  -0.927  -0.988  -1.455
410   R         0.698   0.708   0.736   0.664   0.681   0.732   0.726   0.740   0.777
411   D         0.698   0.708   0.736   0.670   0.687   0.737   0.726   0.740   0.777
412   H        -1.402  -1.438  -1.473  -1.000  -1.059  -1.195  -1.435  -1.452  -1.470
413   I        -0.181  -0.319  -0.629  -0.130  -0.299  -0.766  -0.164  -0.357  -0.855
414   N        -2.383  -2.261  -2.070  -2.447  -2.248  -1.997  -2.198  -2.063  -1.773
415   P        -0.614  -0.496  -0.645  -0.416  -0.247  -0.551  -0.800  -0.621  -0.881
416   D        -2.383  -2.389  -2.077  -2.371  -2.372  -1.942  -2.198  -2.173  -1.779
417   D         0.698   0.708   0.736   0.670   0.687   0.737   0.726   0.740   0.777
418   L        -0.181  -0.343  -0.632  -0.256  -0.459  -0.811  -0.164  -0.393  -0.859
419   M        -1.018  -1.117  -1.466  -0.567  -0.707  -1.360  -0.927  -1.055  -1.462
420   K        -0.181  -0.319  -0.629  -0.103  -0.272  -0.720  -0.164  -0.357  -0.855
421   A         0.698   0.708   0.736   0.684   0.704   0.748   0.726   0.740   0.777
422   V        -1.402  -1.361  -1.477  -1.249  -1.226  -1.330  -1.435  -1.394  -1.475
423   R         0.698   0.708   0.736   0.664   0.681   0.732   0.726   0.740   0.777
424   K         0.698   0.708   0.736   0.634   0.651   0.707   0.726   0.740   0.777
425   V         0.698   0.708   0.736   0.770   0.773   0.819   0.726   0.740   0.777
426   A        -0.181  -0.120  -0.623  -0.053   0.025  -0.675  -0.164  -0.084  -0.845
427   E        -0.845  -0.803  -0.669  -1.250  -1.174  -0.940  -1.181  -1.117  -0.921
428   V        -1.806  -1.999  -2.067  -1.481  -1.813  -1.968  -1.562  -1.770  -1.770
429   K         0.698   0.708   0.736   0.634   0.651   0.707   0.726   0.740   0.777
430   K         0.698   0.708   0.736   0.634   0.651   0.707   0.726   0.740   0.777
431   L         0.698   0.708   0.736   0.472   0.482   0.575   0.726   0.740   0.777
432   E         0.698   0.708   0.736   0.534   0.559   0.625   0.726   0.740   0.777
433   G         0.698   0.708   0.736   0.644   0.659   0.716   0.726   0.740   0.777
434   T        -0.845  -0.816  -0.671  -1.087  -1.039  -0.801  -1.181  -1.139  -0.925
435   I        -0.845  -0.814  -0.673  -1.333  -1.290  -1.016  -1.181  -1.136  -0.929
436   E        -0.845  -0.803  -0.669  -1.250  -1.174  -0.940  -1.181  -1.117  -0.921
437   Y         0.698   0.708   0.736   0.971   0.976   0.985   0.726   0.740   0.777
438   Q        -0.845  -0.735  -0.661  -0.974  -0.762  -0.737  -1.181  -1.003  -0.909
439   K         0.698   0.708   0.736   0.634   0.651   0.707   0.726   0.740   0.777
440   L         0.698   0.708   0.736   0.472   0.482   0.575   0.726   0.740   0.777
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P53549
Output conservation file - output/P53549
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
