1     M         1.526   1.542   1.619   1.733   1.749   1.863   1.651   1.676   1.796
2     S         0.195   0.089  -0.107   0.310   0.170  -0.117   0.199   0.045  -0.247
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     Y        -1.177  -1.186  -1.127  -1.050  -1.080  -0.999  -1.030  -1.036  -0.933
5     R         0.844   0.893   0.637   1.058   1.112   0.775   0.869   0.941   0.493
6     G         0.195   0.116  -0.094   0.344   0.234  -0.052   0.199   0.081  -0.229
7     P        -0.668  -0.603  -0.683  -0.434  -0.350  -0.476  -0.694  -0.624  -0.687
8     I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     G        -0.879  -0.885  -0.769  -0.844  -0.851  -0.678  -0.930  -0.928  -0.778
10    N        -1.277  -1.295  -1.176  -1.039  -1.067  -0.910  -1.121  -1.125  -0.973
11    F        -0.668  -0.620  -0.697  -0.722  -0.656  -0.779  -0.694  -0.650  -0.702
12    G        -0.982  -1.036  -1.089  -0.692  -0.771  -0.820  -0.806  -0.867  -0.892
13    G        -1.277  -1.219  -1.153  -1.059  -0.971  -0.879  -1.121  -1.062  -0.953
14    M        -1.277  -1.146  -1.157  -1.166  -1.014  -1.000  -1.121  -0.995  -0.957
15    P         0.085   0.202  -0.092   0.360   0.518   0.050   0.046   0.209  -0.226
16    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
19    M        -0.721  -0.709  -0.716  -0.746  -0.745  -0.747  -0.732  -0.719  -0.716
20    S        -1.297  -1.272  -1.164  -1.234  -1.180  -1.040  -1.129  -1.100  -0.961
21    S        -1.277  -1.241  -1.155  -1.193  -1.143  -1.007  -1.121  -1.081  -0.955
22    S        -0.561  -0.571  -0.689  -0.449  -0.458  -0.642  -0.537  -0.553  -0.685
23    Q        -1.142  -1.180  -1.136  -0.831  -0.904  -0.868  -0.975  -1.011  -0.936
24    G         0.085   0.189  -0.125   0.398   0.537   0.058   0.046   0.190  -0.272
25    P        -0.784  -0.756  -0.746  -0.609  -0.565  -0.590  -0.829  -0.787  -0.754
26    Y        -1.297  -1.201  -1.155  -1.164  -1.031  -0.948  -1.129  -1.029  -0.953
27    S        -1.385  -1.356  -1.193  -1.169  -1.113  -0.900  -1.208  -1.174  -0.986
28    G        -0.784  -0.789  -0.744  -0.903  -0.898  -0.835  -0.829  -0.826  -0.751
29    G        -0.668  -0.730  -0.710  -0.675  -0.793  -0.755  -0.694  -0.763  -0.718
30    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
31    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
32    -         0.711   0.635   0.572   0.910   0.795   0.666   0.658   0.526   0.372
33    -        -0.879  -0.813  -0.755  -0.880  -0.738  -0.685  -0.930  -0.855  -0.765
34    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
35    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
36    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
37    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
38    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
39    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
40    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
41    A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
42    Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
43    F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
44    R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
45    S        -0.884  -0.824  -0.756  -0.849  -0.755  -0.656  -0.922  -0.855  -0.762
46    N        -0.884  -0.819  -0.756  -0.972  -0.870  -0.779  -0.922  -0.854  -0.763
47    Q        -0.884  -0.824  -0.756  -0.596  -0.521  -0.421  -0.922  -0.855  -0.762
48    N        -0.884  -0.911  -0.787  -0.947  -1.026  -0.861  -0.922  -0.953  -0.796
49    Q        -0.884  -0.909  -0.790  -0.784  -0.840  -0.685  -0.922  -0.951  -0.799
50    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
51    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
52    S         0.195   0.021  -0.118   0.289   0.056  -0.178   0.199  -0.046  -0.264
53    T        -0.236  -0.158  -0.200  -0.343  -0.215  -0.258  -0.471  -0.364  -0.395
54    S        -1.177  -1.194  -1.136  -1.024  -1.050  -0.949  -1.030  -1.043  -0.940
55    G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
56    I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
57    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
58    K        -1.177  -1.139  -1.131  -1.002  -0.975  -0.925  -1.030  -0.997  -0.936
59    Q        -1.177  -1.167  -1.132  -1.036  -1.036  -0.947  -1.030  -1.021  -0.937
60    W        -1.922  -1.886  -1.758  -1.546  -1.517  -1.347  -1.365  -1.331  -1.171
61    K        -1.177  -1.128  -1.126  -1.199  -1.113  -1.129  -1.030  -0.976  -0.930
62    H        -1.490  -1.427  -1.442  -0.949  -0.887  -0.882  -1.141  -1.083  -1.049
63    S        -1.608  -1.577  -1.475  -1.442  -1.391  -1.291  -1.253  -1.219  -1.077
64    F        -0.416  -0.433  -0.638  -0.342  -0.375  -0.698  -0.359  -0.381  -0.626
65    E        -0.416  -0.566  -0.680  -0.018  -0.243  -0.446  -0.359  -0.545  -0.675
66    K        -1.177  -1.218  -1.141  -0.884  -0.930  -0.809  -1.030  -1.057  -0.942
67    F        -0.668  -0.749  -0.726  -0.693  -0.807  -0.747  -0.694  -0.782  -0.735
68    A        -0.103  -0.073  -0.187  -0.061  -0.040  -0.209  -0.248  -0.225  -0.370
69    S        -1.177  -1.231  -1.134  -0.923  -0.961  -0.822  -1.030  -1.069  -0.938
70    R        -0.103  -0.139  -0.170   0.021  -0.008  -0.064  -0.248  -0.279  -0.343
71    I        -0.236  -0.309  -0.222  -0.509  -0.609  -0.470  -0.471  -0.546  -0.427
72    E         0.844   0.724   0.613   1.151   1.002   0.843   0.869   0.676   0.449
73    G        -0.416  -0.508  -0.649  -0.071  -0.204  -0.447  -0.359  -0.480  -0.639
74    L        -0.982  -1.069  -1.110  -0.995  -1.115  -1.127  -0.806  -0.900  -0.911
75    T        -0.863  -0.901  -0.777  -1.085  -1.147  -0.974  -0.918  -0.943  -0.788
76    D        -0.103  -0.105  -0.190   0.112   0.095  -0.029  -0.248  -0.268  -0.379
77    N        -1.922  -1.894  -1.767  -1.365  -1.353  -1.186  -1.365  -1.336  -1.177
78    A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
79    V        -1.177  -1.093  -1.131  -1.210  -1.096  -1.210  -1.030  -0.957  -0.936
80    V        -1.177  -1.178  -1.150  -1.174  -1.164  -1.101  -1.030  -1.031  -0.952
81    Y        -1.922  -1.845  -1.749  -1.591  -1.485  -1.355  -1.365  -1.298  -1.165
82    K        -0.668  -0.541  -0.682  -0.431  -0.238  -0.464  -0.694  -0.536  -0.682
83    L        -0.745  -0.831  -0.728  -1.104  -1.209  -1.051  -0.806  -0.876  -0.738
84    K        -0.416  -0.447  -0.636  -0.151  -0.201  -0.487  -0.359  -0.405  -0.624
85    P         1.526   1.542   1.619   1.705   1.722   1.836   1.651   1.676   1.796
86    Y         0.844   0.785   0.620   1.063   1.001   0.785   0.869   0.775   0.462
87    I        -1.177  -1.171  -1.135  -1.305  -1.298  -1.216  -1.030  -1.025  -0.939
88    P         1.526   1.542   1.619   1.705   1.722   1.836   1.651   1.676   1.796
89    S        -1.177  -1.229  -1.137  -1.223  -1.326  -1.192  -1.030  -1.069  -0.940
90    L         0.329   0.315   0.411  -0.096  -0.147  -0.016  -0.024  -0.063   0.063
91    S        -0.103   0.006  -0.163  -0.144   0.027  -0.233  -0.248  -0.092  -0.332
92    R         1.526   1.542   1.619   1.638   1.652   1.773   1.651   1.676   1.796
93    F         0.509   0.588   0.523   0.379   0.498   0.387   0.311   0.445   0.281
94    F         0.329   0.305   0.411  -0.098  -0.179  -0.019  -0.024  -0.083   0.062
95    I         0.844   0.911   0.637   0.808   0.899   0.478   0.869   0.968   0.492
96    V         1.526   1.542   1.619   1.427   1.445   1.572   1.651   1.676   1.796
97    A         0.509   0.484   0.471   0.456   0.399   0.336   0.311   0.259   0.182
98    T         1.526   1.542   1.619   1.568   1.587   1.706   1.651   1.676   1.796
99    F         0.844   0.724   0.613   0.859   0.709   0.555   0.869   0.676   0.449
100   Y        -0.416  -0.566  -0.680  -0.221  -0.462  -0.731  -0.359  -0.545  -0.675
101   E         1.526   1.542   1.619   1.715   1.734   1.846   1.651   1.676   1.796
102   D         1.526   1.542   1.619   1.670   1.691   1.804   1.651   1.676   1.796
103   S        -0.236  -0.199  -0.226  -0.365  -0.321  -0.315  -0.471  -0.438  -0.433
104   F        -0.103  -0.145  -0.169  -0.426  -0.468  -0.520  -0.248  -0.288  -0.340
105   R         1.526   1.542   1.619   1.638   1.652   1.773   1.651   1.676   1.796
106   I         1.526   1.542   1.619   1.440   1.465   1.584   1.651   1.676   1.796
107   L        -1.177  -1.162  -1.126  -1.303  -1.295  -1.215  -1.030  -1.010  -0.931
108   S         0.195   0.323  -0.066   0.388   0.550   0.001   0.199   0.373  -0.188
109   Q         1.526   1.542   1.619   1.678   1.700   1.811   1.651   1.676   1.796
110   W         1.526   1.542   1.619   1.779   1.800   1.907   1.651   1.676   1.796
111   S        -0.103  -0.172  -0.192  -0.070  -0.140  -0.171  -0.248  -0.329  -0.378
112   D         0.329   0.336   0.421   0.356   0.362   0.478  -0.024  -0.021   0.083
113   Q         1.526   1.542   1.619   1.678   1.700   1.811   1.651   1.676   1.796
114   I         0.195   0.282  -0.064   0.188   0.301  -0.236   0.199   0.317  -0.185
115   F        -0.745  -0.792  -0.741  -0.854  -0.905  -0.863  -0.806  -0.841  -0.751
116   Y         1.526   1.542   1.619   1.617   1.643   1.753   1.651   1.676   1.796
117   L         0.195   0.021  -0.118   0.090  -0.127  -0.317   0.199  -0.046  -0.264
118   N        -1.490  -1.482  -1.440  -0.894  -0.904  -0.854  -1.141  -1.133  -1.048
119   K        -0.355  -0.342  -0.258  -0.301  -0.276  -0.172  -0.583  -0.570  -0.464
120   W        -0.103  -0.095  -0.159   0.064   0.084  -0.032  -0.248  -0.221  -0.326
121   K         0.329   0.354   0.428   0.258   0.292   0.388  -0.024   0.014   0.096
122   H         0.844   0.724   0.613   1.211   1.055   0.879   0.869   0.676   0.449
123   Y        -0.863  -0.838  -0.766  -1.027  -1.009  -0.929  -0.918  -0.897  -0.779
124   P        -0.103  -0.145  -0.179   0.179   0.129   0.070  -0.248  -0.288  -0.354
125   Y        -1.177  -1.241  -1.159  -0.948  -1.046  -0.933  -1.030  -1.076  -0.958
126   F        -1.295  -1.233  -1.157  -1.208  -1.137  -1.027  -1.141  -1.080  -0.958
127   F        -1.177  -1.246  -1.133  -1.393  -1.485  -1.342  -1.030  -1.081  -0.938
128   V        -0.236  -0.286  -0.223  -0.371  -0.416  -0.316  -0.471  -0.510  -0.422
129   V         0.195   0.089  -0.107   0.326   0.191  -0.030   0.199   0.045  -0.247
130   V        -0.668  -0.620  -0.683  -0.986  -0.895  -1.002  -0.694  -0.624  -0.686
131   F         0.844   0.724   0.613   0.806   0.633   0.432   0.869   0.676   0.449
132   L         1.526   1.542   1.619   1.246   1.273   1.400   1.651   1.676   1.796
133   V        -0.863  -0.792  -0.747  -1.291  -1.186  -1.094  -0.918  -0.846  -0.757
134   V        -1.490  -1.405  -1.427  -1.389  -1.288  -1.310  -1.141  -1.059  -1.037
135   V        -0.236  -0.286  -0.223  -0.256  -0.273  -0.171  -0.471  -0.510  -0.422
136   T        -0.103   0.010  -0.141  -0.138   0.017  -0.157  -0.248  -0.087  -0.300
137   V        -0.236  -0.162  -0.195  -0.550  -0.433  -0.486  -0.471  -0.377  -0.391
138   S        -1.295  -1.291  -1.169  -1.363  -1.378  -1.155  -1.141  -1.125  -0.968
139   M         1.526   1.542   1.619   1.733   1.749   1.863   1.651   1.676   1.796
140   L        -0.982  -0.948  -1.071  -1.084  -1.037  -1.215  -0.806  -0.769  -0.874
141   I        -1.608  -1.548  -1.468  -1.622  -1.534  -1.411  -1.253  -1.197  -1.072
142   G        -0.103  -0.031  -0.155  -0.064   0.051  -0.101  -0.248  -0.139  -0.320
143   A         0.329   0.392   0.452   0.104   0.214   0.292  -0.024   0.087   0.144
144   S         0.195   0.211  -0.078   0.368   0.382  -0.058   0.199   0.215  -0.205
145   L         0.844   0.785   0.620   0.685   0.624   0.431   0.869   0.775   0.462
146   L         0.272   0.304   0.414  -0.266  -0.195  -0.017  -0.136  -0.085   0.068
147   V        -0.236  -0.273  -0.220  -0.478  -0.524  -0.419  -0.471  -0.509  -0.424
148   L        -0.668  -0.749  -0.726  -0.916  -1.032  -0.977  -0.694  -0.782  -0.735
149   R         0.509   0.416   0.450   0.578   0.408   0.432   0.311   0.132   0.139
150   K         1.526   1.542   1.619   1.580   1.603   1.718   1.651   1.676   1.796
151   Q        -1.295  -1.237  -1.163  -1.006  -0.927  -0.796  -1.141  -1.079  -0.963
152   T        -1.490  -1.518  -1.480  -1.161  -1.213  -1.157  -1.141  -1.163  -1.079
153   N        -0.745  -0.766  -0.722  -0.573  -0.593  -0.544  -0.806  -0.818  -0.733
154   Y        -0.103  -0.055  -0.191  -0.067  -0.004  -0.255  -0.248  -0.193  -0.377
155   A         0.844   0.785   0.620   0.965   0.885   0.641   0.869   0.775   0.462
156   T        -0.416  -0.566  -0.680  -0.164  -0.379  -0.568  -0.359  -0.545  -0.675
157   G        -0.416  -0.272  -0.621  -0.303  -0.095  -0.650  -0.359  -0.180  -0.605
158   V        -1.177  -1.241  -1.144  -1.236  -1.355  -1.235  -1.030  -1.076  -0.945
159   L         1.526   1.542   1.619   1.246   1.273   1.400   1.651   1.676   1.796
160   C        -0.863  -0.894  -0.752  -0.979  -1.054  -0.845  -0.918  -0.935  -0.762
161   A        -1.177  -1.133  -1.114  -1.020  -0.980  -0.943  -1.030  -0.981  -0.920
162   C        -0.668  -0.532  -0.683  -0.599  -0.421  -0.614  -0.694  -0.528  -0.682
163   V        -0.103  -0.214  -0.203  -0.221  -0.385  -0.385  -0.248  -0.394  -0.396
164   I        -0.416  -0.522  -0.657  -0.378  -0.564  -0.799  -0.359  -0.496  -0.649
165   S        -1.177  -1.079  -1.109  -1.301  -1.168  -1.165  -1.030  -0.940  -0.915
166   Q         1.526   1.542   1.619   1.678   1.700   1.811   1.651   1.676   1.796
167   A         0.329   0.392   0.439   0.147   0.258   0.303  -0.024   0.087   0.118
168   L         0.195   0.132  -0.095   0.036  -0.053  -0.394   0.199   0.102  -0.230
169   V        -0.432  -0.388  -0.283  -0.686  -0.608  -0.445  -0.694  -0.636  -0.499
170   Y         1.526   1.542   1.619   1.617   1.643   1.753   1.651   1.676   1.796
171   G         1.526   1.542   1.619   1.495   1.520   1.636   1.651   1.676   1.796
172   L         1.526   1.542   1.619   1.246   1.273   1.400   1.651   1.676   1.796
173   F        -0.236  -0.150  -0.201  -0.540  -0.391  -0.484  -0.471  -0.354  -0.393
174   T        -0.236  -0.199  -0.219  -0.410  -0.360  -0.360  -0.471  -0.428  -0.424
175   G        -0.236  -0.286  -0.223  -0.263  -0.307  -0.231  -0.471  -0.510  -0.422
176   S        -1.177  -1.181  -1.143  -1.266  -1.282  -1.249  -1.030  -1.031  -0.946
177   S        -1.608  -1.632  -1.495  -1.329  -1.338  -1.157  -1.253  -1.258  -1.091
178   F         0.844   0.724   0.613   0.876   0.731   0.594   0.869   0.676   0.449
179   V        -0.355  -0.385  -0.288  -0.652  -0.720  -0.577  -0.583  -0.628  -0.506
180   L         0.844   0.724   0.613   0.640   0.484   0.316   0.869   0.676   0.449
181   R         1.526   1.542   1.619   1.638   1.652   1.773   1.651   1.676   1.796
182   N         1.526   1.542   1.619   1.646   1.674   1.780   1.651   1.676   1.796
183   F        -0.668  -0.662  -0.710  -0.902  -0.861  -0.913  -0.694  -0.682  -0.715
184   S         1.526   1.542   1.619   1.474   1.500   1.616   1.651   1.676   1.796
185   V         1.526   1.542   1.619   1.427   1.445   1.572   1.651   1.676   1.796
186   I        -0.103  -0.031  -0.155  -0.180  -0.060  -0.227  -0.248  -0.139  -0.320
187   G         1.526   1.542   1.619   1.495   1.520   1.636   1.651   1.676   1.796
188   G         1.526   1.542   1.619   1.495   1.520   1.636   1.651   1.676   1.796
189   L         1.526   1.542   1.619   1.246   1.273   1.400   1.651   1.676   1.796
190   L        -0.982  -1.032  -1.106  -1.054  -1.102  -1.215  -0.806  -0.864  -0.908
191   I        -0.236  -0.222  -0.221  -0.555  -0.537  -0.476  -0.471  -0.454  -0.426
192   A         0.509   0.450   0.464   0.456   0.336   0.320   0.311   0.196   0.167
193   F        -0.103  -0.225  -0.215  -0.286  -0.484  -0.502  -0.248  -0.412  -0.410
194   S         0.195   0.183  -0.090   0.312   0.306  -0.086   0.199   0.179  -0.223
195   D         1.526   1.542   1.619   1.670   1.691   1.804   1.651   1.676   1.796
196   S        -0.103  -0.185  -0.203  -0.128  -0.248  -0.280  -0.248  -0.363  -0.397
197   I        -0.668  -0.670  -0.725  -0.752  -0.782  -0.843  -0.694  -0.717  -0.734
198   V         0.844   0.724   0.613   0.822   0.658   0.486   0.869   0.676   0.449
199   Q        -0.982  -1.023  -1.089  -0.552  -0.615  -0.704  -0.806  -0.855  -0.891
200   N        -0.745  -0.792  -0.741  -0.552  -0.599  -0.523  -0.806  -0.841  -0.751
201   K        -0.103  -0.129  -0.197   0.000  -0.051  -0.148  -0.248  -0.297  -0.388
202   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
203   T        -1.608  -1.628  -1.497  -1.291  -1.319  -1.125  -1.253  -1.255  -1.093
204   T        -1.177  -1.241  -1.159  -1.046  -1.120  -1.003  -1.030  -1.076  -0.958
205   F        -0.103  -0.095  -0.172  -0.271  -0.227  -0.372  -0.248  -0.221  -0.345
206   G        -0.745  -0.659  -0.705  -0.758  -0.643  -0.671  -0.806  -0.718  -0.717
207   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
208   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
209   M         0.329   0.392   0.452   0.215   0.314   0.401  -0.024   0.087   0.144
210   L         1.526   1.542   1.619   1.246   1.273   1.400   1.651   1.676   1.796
211   P         1.526   1.542   1.619   1.705   1.722   1.836   1.651   1.676   1.796
212   E        -1.177  -1.241  -1.159  -0.837  -0.944  -0.850  -1.030  -1.076  -0.958
213   L        -0.103  -0.205  -0.202  -0.427  -0.574  -0.582  -0.248  -0.379  -0.393
214   N        -0.668  -0.750  -0.724  -0.426  -0.545  -0.511  -0.694  -0.784  -0.734
215   S        -0.863  -0.879  -0.776  -0.782  -0.771  -0.611  -0.918  -0.925  -0.787
216   K        -0.103  -0.145  -0.179   0.057   0.027  -0.021  -0.248  -0.288  -0.354
217   N         0.509   0.484   0.460   0.630   0.588   0.513   0.311   0.258   0.160
218   D        -1.295  -1.287  -1.170  -1.066  -1.051  -0.896  -1.141  -1.122  -0.968
219   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
220   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
221   K         0.195   0.021  -0.118   0.413   0.180  -0.049   0.199  -0.046  -0.264
222   G        -1.177  -1.178  -1.138  -0.978  -0.969  -0.889  -1.030  -1.020  -0.939
223   Y         1.526   1.542   1.619   1.617   1.643   1.753   1.651   1.676   1.796
224   L        -0.236  -0.244  -0.218  -0.627  -0.602  -0.565  -0.471  -0.459  -0.415
225   L         0.509   0.450   0.464   0.233   0.152   0.185   0.311   0.196   0.167
226   F         0.844   0.936   0.641   0.640   0.759   0.361   0.869   1.005   0.499
227   A         1.526   1.542   1.619   1.562   1.577   1.700   1.651   1.676   1.796
228   G         1.526   1.542   1.619   1.495   1.520   1.636   1.651   1.676   1.796
229   R         1.526   1.542   1.619   1.638   1.652   1.773   1.651   1.676   1.796
230   I        -0.668  -0.632  -0.698  -0.769  -0.742  -0.821  -0.694  -0.670  -0.703
231   L         1.526   1.542   1.619   1.246   1.273   1.400   1.651   1.676   1.796
232   I        -0.103   0.006  -0.163  -0.362  -0.198  -0.399  -0.248  -0.092  -0.332
233   V         0.509   0.450   0.464   0.328   0.217   0.211   0.311   0.196   0.167
234   L        -0.668  -0.719  -0.724  -0.983  -1.070  -1.062  -0.694  -0.761  -0.733
235   M         0.272   0.298   0.410  -0.027   0.043   0.206  -0.136  -0.095   0.061
236   F         1.526   1.542   1.619   1.438   1.458   1.582   1.651   1.676   1.796
237   I        -0.236  -0.273  -0.229  -0.593  -0.641  -0.553  -0.471  -0.509  -0.435
238   A        -0.668  -0.630  -0.702  -0.643  -0.578  -0.690  -0.694  -0.639  -0.704
239   F         0.844   0.724   0.613   0.806   0.633   0.432   0.869   0.676   0.449
240   T        -0.745  -0.832  -0.746  -0.909  -1.055  -0.942  -0.806  -0.877  -0.757
241   F         0.195   0.021  -0.118   0.220  -0.029  -0.280   0.199  -0.046  -0.264
242   S        -0.416  -0.532  -0.661  -0.233  -0.386  -0.573  -0.359  -0.507  -0.654
243   K        -1.490  -1.518  -1.480  -1.140  -1.164  -1.136  -1.141  -1.163  -1.079
244   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
245   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
246   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
247   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
248   S        -0.416  -0.418  -0.640  -0.200  -0.203  -0.486  -0.359  -0.364  -0.628
249   W         0.844   0.893   0.637   1.174   1.237   0.852   0.869   0.941   0.493
250   -         0.308   0.376   0.445   0.145   0.269   0.354  -0.065   0.055   0.129
251   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
252   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
253   -         1.526   1.542   1.619   1.628   1.644   1.763   1.651   1.676   1.796
254   -        -0.382  -0.323  -0.266  -0.826  -0.716  -0.659  -0.636  -0.563  -0.480
255   F        -0.863  -0.766  -0.744  -1.291  -1.138  -1.092  -0.918  -0.807  -0.755
256   T        -0.432  -0.371  -0.276  -0.707  -0.619  -0.477  -0.694  -0.614  -0.490
257   V        -0.863  -0.898  -0.766  -1.013  -1.019  -0.823  -0.918  -0.940  -0.777
258   V        -0.236  -0.181  -0.210  -0.668  -0.588  -0.590  -0.471  -0.420  -0.413
259   L        -0.863  -0.805  -0.759  -1.283  -1.197  -1.099  -0.918  -0.857  -0.771
260   T        -0.236  -0.286  -0.223  -0.363  -0.414  -0.324  -0.471  -0.510  -0.422
261   I        -0.863  -0.819  -0.758  -1.238  -1.171  -1.081  -0.918  -0.874  -0.771
262   I        -0.863  -0.822  -0.757  -0.996  -0.946  -0.828  -0.918  -0.882  -0.770
263   G        -0.863  -0.761  -0.750  -0.880  -0.713  -0.672  -0.918  -0.796  -0.758
264   T         0.329   0.392   0.452   0.393   0.508   0.564  -0.024   0.087   0.144
265   I        -1.177  -1.138  -1.123  -1.221  -1.173  -1.143  -1.030  -0.996  -0.929
266   C        -0.432  -0.371  -0.276  -0.330  -0.233  -0.118  -0.694  -0.614  -0.490
267   F        -0.432  -0.371  -0.276  -0.800  -0.699  -0.556  -0.694  -0.614  -0.491
268   A         0.329   0.392   0.452   0.063   0.163   0.254  -0.024   0.087   0.144
269   I         0.272   0.293   0.408  -0.120  -0.088   0.099  -0.136  -0.106   0.057
270   G         1.526   1.542   1.619   1.495   1.520   1.636   1.651   1.676   1.796
271   Y         0.329   0.305   0.411   0.166   0.095   0.244  -0.024  -0.083   0.062
272   K         1.526   1.542   1.619   1.580   1.603   1.718   1.651   1.676   1.796
273   T         0.509   0.416   0.450   0.505   0.337   0.365   0.311   0.132   0.139
274   K         0.844   0.785   0.620   1.004   0.934   0.703   0.869   0.775   0.462
275   F         0.844   0.785   0.620   0.831   0.753   0.504   0.869   0.775   0.462
276   A        -0.236  -0.310  -0.228  -0.373  -0.483  -0.361  -0.471  -0.549  -0.435
277   S         0.272   0.298   0.411   0.005   0.052   0.228  -0.136  -0.095   0.064
278   I        -0.863  -0.860  -0.773  -1.021  -1.017  -0.863  -0.918  -0.912  -0.785
279   M        -1.295  -1.287  -1.170  -1.435  -1.456  -1.269  -1.141  -1.122  -0.968
280   L         0.844   0.911   0.637   0.685   0.769   0.454   0.869   0.968   0.492
281   G        -1.177  -1.157  -1.149  -1.176  -1.146  -1.130  -1.030  -1.013  -0.951
282   L        -0.863  -0.817  -0.759  -1.294  -1.222  -1.113  -0.918  -0.865  -0.771
283   I         0.195   0.311  -0.078   0.199   0.361  -0.253   0.199   0.357  -0.205
284   L         1.526   1.542   1.619   1.246   1.273   1.400   1.651   1.676   1.796
285   T        -0.863  -0.817  -0.763  -1.002  -0.946  -0.837  -0.918  -0.869  -0.773
286   F        -1.177  -1.178  -1.150  -1.357  -1.373  -1.361  -1.030  -1.031  -0.952
287   Y        -0.103  -0.225  -0.215  -0.041  -0.229  -0.253  -0.248  -0.412  -0.410
288   N         1.526   1.542   1.619   1.646   1.674   1.780   1.651   1.676   1.796
289   I        -0.745  -0.792  -0.724  -1.009  -1.075  -0.988  -0.806  -0.841  -0.735
290   T        -0.668  -0.703  -0.709  -0.713  -0.759  -0.836  -0.694  -0.721  -0.712
291   L        -1.177  -1.215  -1.124  -1.360  -1.410  -1.251  -1.030  -1.054  -0.927
292   N         1.526   1.542   1.619   1.646   1.674   1.780   1.651   1.676   1.796
293   N        -0.355  -0.360  -0.273  -0.341  -0.372  -0.260  -0.583  -0.597  -0.486
294   Y         0.272   0.294   0.408   0.021   0.053   0.231  -0.136  -0.104   0.057
295   W         1.526   1.542   1.619   1.779   1.800   1.907   1.651   1.676   1.796
296   F        -1.177  -1.198  -1.147  -1.121  -1.164  -1.044  -1.030  -1.045  -0.949
297   Y        -0.416  -0.566  -0.680  -0.223  -0.460  -0.736  -0.359  -0.545  -0.675
298   -        -0.884  -0.770  -0.760  -0.715  -0.534  -0.553  -0.922  -0.788  -0.767
299   -        -0.884  -0.906  -0.791  -0.842  -0.876  -0.694  -0.922  -0.945  -0.800
300   N        -1.922  -1.889  -1.758  -1.356  -1.316  -1.158  -1.365  -1.332  -1.171
301   N        -0.863  -0.785  -0.731  -0.774  -0.660  -0.556  -0.918  -0.820  -0.737
302   T        -0.745  -0.638  -0.717  -0.667  -0.504  -0.599  -0.806  -0.693  -0.728
303   K        -1.490  -1.518  -1.480  -1.123  -1.179  -1.112  -1.141  -1.163  -1.079
304   R         0.844   0.862   0.632   1.053   1.070   0.756   0.869   0.894   0.484
305   D         1.526   1.542   1.619   1.670   1.691   1.804   1.651   1.676   1.796
306   F         0.844   0.785   0.620   0.859   0.789   0.566   0.869   0.775   0.462
307   L         0.195   0.089  -0.107   0.090  -0.042  -0.300   0.199   0.045  -0.247
308   K         0.509   0.472   0.459   0.541   0.478   0.432   0.311   0.237   0.158
309   Y         1.526   1.542   1.619   1.617   1.643   1.753   1.651   1.676   1.796
310   E         0.509   0.450   0.464   0.680   0.579   0.567   0.311   0.196   0.167
311   F         0.844   0.785   0.620   0.885   0.819   0.624   0.869   0.775   0.462
312   Y         0.329   0.392   0.452   0.103   0.207   0.293  -0.024   0.087   0.144
313   Q         1.526   1.542   1.619   1.678   1.700   1.811   1.651   1.676   1.796
314   N        -0.745  -0.684  -0.717  -0.704  -0.616  -0.676  -0.806  -0.736  -0.725
315   L         1.526   1.542   1.619   1.246   1.273   1.400   1.651   1.676   1.796
316   S         1.526   1.542   1.619   1.474   1.500   1.616   1.651   1.676   1.796
317   I         1.526   1.542   1.619   1.440   1.465   1.584   1.651   1.676   1.796
318   I         0.272   0.294   0.408  -0.120  -0.087   0.099  -0.136  -0.104   0.057
319   G         1.526   1.542   1.619   1.495   1.520   1.636   1.651   1.676   1.796
320   G         1.526   1.542   1.619   1.495   1.520   1.636   1.651   1.676   1.796
321   L         1.526   1.542   1.619   1.246   1.273   1.400   1.651   1.676   1.796
322   L         0.844   0.917   0.638   0.685   0.776   0.455   0.869   0.978   0.494
323   L         0.195   0.138  -0.093   0.068   0.002  -0.324   0.199   0.110  -0.227
324   V        -0.355  -0.344  -0.271  -0.738  -0.746  -0.646  -0.583  -0.573  -0.482
325   T        -0.236  -0.165  -0.211  -0.415  -0.316  -0.350  -0.471  -0.376  -0.410
326   N         1.526   1.542   1.619   1.646   1.674   1.780   1.651   1.676   1.796
327   T         0.509   0.588   0.523   0.505   0.624   0.502   0.311   0.445   0.281
328   G         1.526   1.542   1.619   1.495   1.520   1.636   1.651   1.676   1.796
329   A         0.509   0.450   0.464   0.545   0.445   0.459   0.311   0.196   0.167
330   G         1.526   1.542   1.619   1.495   1.520   1.636   1.651   1.676   1.796
331   E        -0.355  -0.380  -0.290  -0.240  -0.303  -0.182  -0.583  -0.624  -0.509
332   L        -0.236  -0.277  -0.225  -0.666  -0.707  -0.605  -0.471  -0.515  -0.432
333   S         1.526   1.542   1.619   1.474   1.500   1.616   1.651   1.676   1.796
334   V        -0.236  -0.183  -0.207  -0.547  -0.472  -0.506  -0.471  -0.413  -0.407
335   D         1.526   1.542   1.619   1.670   1.691   1.804   1.651   1.676   1.796
336   E         0.844   0.893   0.637   1.115   1.176   0.803   0.869   0.941   0.493
337   K         1.526   1.542   1.619   1.580   1.603   1.718   1.651   1.676   1.796
338   K         1.526   1.542   1.619   1.580   1.603   1.718   1.651   1.676   1.796
339   K         0.844   0.893   0.637   1.004   1.064   0.729   0.869   0.941   0.493
340   I         0.509   0.484   0.471   0.337   0.290   0.231   0.311   0.259   0.182
341   Y         1.526   1.542   1.619   1.617   1.643   1.753   1.651   1.676   1.796
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P53337
Output conservation file - output/P53337
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
