1     M         1.824   1.851   1.908   2.159   2.203   2.291   2.019   2.058   2.147
2     V        -0.124  -0.099  -0.084  -0.286  -0.240  -0.240  -0.351  -0.313  -0.298
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
19    E        -0.504  -0.495  -0.567  -0.507  -0.494  -0.653  -0.509  -0.491  -0.571
20    E        -1.534  -1.521  -1.455  -1.450  -1.459  -1.326  -1.141  -1.121  -1.034
21    N        -0.668  -0.629  -0.638  -0.696  -0.645  -0.651  -0.719  -0.675  -0.659
22    S        -1.101  -1.116  -1.069  -0.892  -0.909  -0.856  -0.930  -0.938  -0.867
23    R         0.198   0.291   0.085   0.113   0.254  -0.072   0.123   0.260  -0.049
24    V        -0.504  -0.578  -0.597  -0.499  -0.623  -0.674  -0.509  -0.595  -0.606
25    L         0.631   0.642   0.662   0.188   0.198   0.214   0.334   0.345   0.350
26    I        -1.101  -1.110  -1.065  -1.061  -1.096  -1.001  -0.930  -0.933  -0.863
27    V        -0.504  -0.523  -0.570  -0.421  -0.463  -0.556  -0.509  -0.530  -0.574
28    L         0.631   0.642   0.662   0.354   0.372   0.409   0.334   0.345   0.350
29    P        -1.534  -1.521  -1.455  -1.481  -1.466  -1.357  -1.141  -1.121  -1.034
30    Y        -1.101  -1.072  -1.062  -1.009  -0.966  -0.936  -0.930  -0.894  -0.860
31    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
32    T        -0.071  -0.052  -0.068  -0.196  -0.171  -0.172  -0.298  -0.272  -0.283
33    P        -0.504  -0.558  -0.575  -0.315  -0.409  -0.428  -0.509  -0.571  -0.580
34    P         0.198   0.273   0.076   0.526   0.638   0.355   0.123   0.233  -0.062
35    S         0.198   0.257   0.082   0.178   0.263  -0.005   0.123   0.210  -0.053
36    A        -1.101  -1.116  -1.069  -0.956  -0.976  -0.887  -0.930  -0.938  -0.867
37    T        -1.101  -1.078  -1.076  -1.112  -1.075  -1.115  -0.930  -0.902  -0.874
38    L        -0.668  -0.614  -0.630  -0.770  -0.713  -0.716  -0.719  -0.658  -0.651
39    Q        -1.101  -1.035  -1.056  -1.167  -1.068  -1.095  -0.930  -0.857  -0.855
40    R        -1.101  -1.101  -1.066  -1.115  -1.133  -1.053  -0.930  -0.925  -0.864
41    I        -0.071  -0.090  -0.076  -0.351  -0.404  -0.395  -0.298  -0.326  -0.298
42    I        -0.504  -0.523  -0.570  -0.674  -0.687  -0.767  -0.509  -0.530  -0.574
43    G        -0.668  -0.658  -0.633  -0.609  -0.579  -0.538  -0.719  -0.702  -0.654
44    Q        -0.668  -0.704  -0.640  -0.668  -0.729  -0.625  -0.719  -0.748  -0.662
45    T        -0.668  -0.628  -0.635  -0.825  -0.783  -0.765  -0.719  -0.672  -0.656
46    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
47    I         0.525   0.551   0.612   0.008   0.063   0.158   0.123   0.164   0.249
48    P         0.043  -0.052  -0.048   0.324   0.182   0.178  -0.104  -0.244  -0.245
49    F        -0.153  -0.091  -0.106  -0.261  -0.181  -0.201  -0.408  -0.327  -0.336
50    L        -0.153  -0.091  -0.106  -0.507  -0.380  -0.420  -0.408  -0.327  -0.336
51    R         0.563   0.606   0.638   0.520   0.594   0.637   0.199   0.275   0.302
52    E        -0.673  -0.613  -0.629  -0.721  -0.625  -0.646  -0.711  -0.636  -0.644
53    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
54    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
55    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
56    C        -1.192  -1.183  -1.113  -0.959  -0.920  -0.834  -1.014  -0.998  -0.907
57    Q        -1.534  -1.521  -1.455  -1.485  -1.449  -1.361  -1.141  -1.121  -1.034
58    S         0.198   0.245   0.072   0.237   0.301   0.062   0.123   0.192  -0.068
59    Q        -1.534  -1.521  -1.455  -1.241  -1.182  -1.116  -1.141  -1.121  -1.034
60    L        -0.071  -0.135  -0.087  -0.523  -0.629  -0.551  -0.298  -0.376  -0.310
61    D         0.980   0.887   0.842   1.127   0.990   0.906   0.966   0.802   0.697
62    I         0.198   0.105   0.039   0.151   0.022  -0.091   0.123  -0.014  -0.116
63    V        -0.071  -0.132  -0.076  -0.239  -0.305  -0.214  -0.298  -0.370  -0.298
64    I        -0.071  -0.100  -0.062  -0.416  -0.426  -0.379  -0.298  -0.320  -0.274
65    V        -1.101  -1.110  -1.065  -1.389  -1.401  -1.329  -0.930  -0.933  -0.863
66    P        -1.534  -1.521  -1.455  -1.127  -1.087  -1.002  -1.141  -1.121  -1.034
67    E        -1.534  -1.521  -1.455  -1.261  -1.242  -1.136  -1.141  -1.121  -1.034
68    F        -0.071  -0.135  -0.087  -0.144  -0.260  -0.192  -0.298  -0.376  -0.310
69    K        -1.101  -1.035  -1.056  -0.899  -0.775  -0.841  -0.930  -0.857  -0.855
70    T        -1.101  -1.107  -1.067  -1.112  -1.160  -1.073  -0.930  -0.930  -0.865
71    S         0.198   0.161   0.055   0.272   0.216   0.085   0.123   0.064  -0.094
72    F        -1.101  -1.078  -1.076  -0.861  -0.818  -0.810  -0.930  -0.902  -0.874
73    Q        -0.668  -0.701  -0.641  -0.502  -0.563  -0.466  -0.719  -0.745  -0.662
74    L         1.824   1.851   1.908   1.616   1.657   1.747   2.019   2.058   2.147
75    D        -0.071  -0.135  -0.087  -0.055  -0.142  -0.067  -0.298  -0.376  -0.310
76    S        -0.504  -0.530  -0.568  -0.524  -0.573  -0.625  -0.509  -0.539  -0.573
77    A        -1.101  -1.044  -1.055  -0.817  -0.722  -0.748  -0.930  -0.866  -0.854
78    L         1.824   1.851   1.908   1.616   1.657   1.747   2.019   2.058   2.147
79    G        -0.071  -0.085  -0.084  -0.037  -0.046  -0.048  -0.298  -0.323  -0.309
80    K        -1.101  -1.091  -1.063  -0.929  -0.937  -0.855  -0.930  -0.916  -0.861
81    M        -0.668  -0.658  -0.633  -0.853  -0.843  -0.759  -0.719  -0.702  -0.654
82    Y         1.824   1.851   1.908   2.034   2.079   2.166   2.019   2.058   2.147
83    S        -0.504  -0.578  -0.597  -0.563  -0.703  -0.721  -0.509  -0.595  -0.606
84    I        -1.101  -1.114  -1.077  -1.250  -1.298  -1.211  -0.930  -0.936  -0.875
85    T        -0.504  -0.495  -0.567  -0.654  -0.644  -0.790  -0.509  -0.491  -0.571
86    R         0.980   0.887   0.842   1.245   1.125   1.056   0.966   0.802   0.697
87    D        -0.504  -0.578  -0.597  -0.375  -0.495  -0.545  -0.509  -0.595  -0.606
88    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
89    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
90    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
91    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
92    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
93    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
94    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
95    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
96    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
97    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
98    V        -0.071  -0.085  -0.084  -0.174  -0.202  -0.196  -0.298  -0.323  -0.309
99    L        -0.504  -0.578  -0.597  -0.650  -0.754  -0.772  -0.509  -0.595  -0.606
100   L        -1.101  -1.078  -1.076  -1.302  -1.247  -1.278  -0.930  -0.902  -0.874
101   G        -1.101  -1.072  -1.062  -1.258  -1.216  -1.203  -0.930  -0.894  -0.860
102   Y        -1.101  -1.137  -1.084  -1.100  -1.168  -1.073  -0.930  -0.956  -0.881
103   G        -0.504  -0.544  -0.572  -0.423  -0.500  -0.547  -0.509  -0.555  -0.577
104   M        -0.504  -0.495  -0.567  -0.438  -0.420  -0.466  -0.509  -0.491  -0.571
105   I        -1.101  -1.078  -1.076  -1.074  -1.050  -1.056  -0.930  -0.902  -0.874
106   N        -1.101  -1.078  -1.076  -0.963  -0.917  -0.946  -0.930  -0.902  -0.874
107   S        -1.101  -1.091  -1.063  -1.023  -1.017  -0.949  -0.930  -0.916  -0.861
108   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
109   G        -0.668  -0.629  -0.638  -0.628  -0.568  -0.567  -0.719  -0.675  -0.659
110   I         0.980   0.887   0.842   0.926   0.790   0.728   0.966   0.802   0.697
111   N         0.198   0.116   0.047   0.311   0.169   0.055   0.123   0.002  -0.105
112   I         0.631   0.649   0.653   0.414   0.442   0.412   0.334   0.359   0.332
113   I         0.631   0.656   0.657   0.188   0.225   0.204   0.334   0.371   0.339
114   F         1.824   1.851   1.908   2.023   2.065   2.154   2.019   2.058   2.147
115   N         0.198   0.179   0.057   0.318   0.274   0.084   0.123   0.088  -0.090
116   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
117   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
118   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
119   N        -0.673  -0.624  -0.629  -0.659  -0.572  -0.595  -0.711  -0.647  -0.644
120   I        -0.153  -0.115  -0.105  -0.483  -0.434  -0.411  -0.408  -0.359  -0.334
121   H        -1.192  -1.184  -1.113  -0.977  -0.961  -0.852  -1.014  -0.998  -0.907
122   -        -0.124  -0.087  -0.084  -0.436  -0.382  -0.371  -0.351  -0.295  -0.297
123   -        -0.774  -0.765  -0.694  -0.810  -0.794  -0.684  -0.825  -0.808  -0.716
124   -        -0.124  -0.081  -0.090  -0.174  -0.113  -0.106  -0.351  -0.286  -0.306
125   F        -0.504  -0.509  -0.569  -0.707  -0.729  -0.808  -0.509  -0.514  -0.574
126   V        -1.101  -1.078  -1.076  -0.810  -0.775  -0.791  -0.930  -0.902  -0.874
127   E        -0.504  -0.530  -0.568  -0.517  -0.564  -0.627  -0.509  -0.539  -0.573
128   S        -0.668  -0.625  -0.628  -0.744  -0.689  -0.674  -0.719  -0.669  -0.650
129   N         0.770   0.835   0.739   0.800   0.890   0.736   0.597   0.708   0.501
130   L        -0.071  -0.037  -0.069  -0.169  -0.107  -0.118  -0.298  -0.268  -0.289
131   Q        -1.101  -1.028  -1.056  -1.185  -1.038  -1.132  -0.930  -0.850  -0.856
132   W        -1.101  -1.123  -1.079  -0.686  -0.741  -0.663  -0.930  -0.944  -0.877
133   K        -1.101  -1.035  -1.056  -1.098  -0.980  -1.031  -0.930  -0.857  -0.855
134   V        -0.071  -0.041  -0.053  -0.007   0.058   0.037  -0.298  -0.249  -0.261
135   V        -0.668  -0.616  -0.629  -0.815  -0.705  -0.758  -0.719  -0.660  -0.650
136   L        -1.101  -1.116  -1.069  -1.082  -1.116  -1.034  -0.930  -0.938  -0.867
137   L        -1.101  -1.028  -1.056  -1.018  -0.914  -0.940  -0.930  -0.850  -0.856
138   P        -1.534  -1.521  -1.455  -1.276  -1.250  -1.152  -1.141  -1.121  -1.034
139   Q        -0.504  -0.567  -0.580  -0.382  -0.464  -0.471  -0.509  -0.582  -0.587
140   E        -1.101  -1.091  -1.063  -1.157  -1.149  -1.099  -0.930  -0.916  -0.861
141   S        -0.235  -0.215  -0.151  -0.340  -0.314  -0.217  -0.509  -0.479  -0.393
142   T        -1.101  -1.114  -1.077  -0.909  -0.918  -0.867  -0.930  -0.936  -0.875
143   F        -0.071  -0.038  -0.058  -0.323  -0.276  -0.286  -0.298  -0.249  -0.272
144   E        -0.673  -0.667  -0.640  -0.743  -0.768  -0.707  -0.711  -0.701  -0.656
145   T         0.043   0.142   0.014   0.111   0.260   0.056  -0.104   0.041  -0.155
146   W        -0.673  -0.716  -0.661  -0.613  -0.736  -0.629  -0.711  -0.756  -0.680
147   K         0.043  -0.055  -0.048   0.050  -0.106  -0.103  -0.104  -0.249  -0.245
148   L        -1.192  -1.174  -1.113  -1.078  -1.056  -0.953  -1.014  -0.990  -0.907
149   E        -0.153  -0.162  -0.107  -0.482  -0.502  -0.422  -0.408  -0.412  -0.336
150   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
151   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
152   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
153   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
154   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
155   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
156   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
157   L        -0.124  -0.121  -0.090  -0.420  -0.411  -0.363  -0.351  -0.345  -0.307
158   G        -1.534  -1.521  -1.455  -1.552  -1.533  -1.428  -1.141  -1.121  -1.034
159   Q        -0.504  -0.443  -0.541  -0.618  -0.537  -0.656  -0.509  -0.428  -0.540
160   G        -1.101  -1.078  -1.076  -1.076  -1.029  -1.053  -0.930  -0.902  -0.874
161   Q        -0.504  -0.535  -0.566  -0.375  -0.432  -0.509  -0.509  -0.544  -0.570
162   Y        -0.668  -0.630  -0.636  -0.674  -0.644  -0.622  -0.719  -0.672  -0.656
163   H        -0.668  -0.660  -0.636  -0.560  -0.537  -0.519  -0.719  -0.701  -0.657
164   S        -1.101  -1.028  -1.056  -1.176  -1.033  -1.122  -0.930  -0.850  -0.856
165   I         0.770   0.825   0.767   0.544   0.633   0.525   0.597   0.689   0.554
166   E         0.770   0.825   0.767   0.659   0.742   0.632   0.597   0.689   0.554
167   H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
168   Y        -0.124  -0.150  -0.108  -0.434  -0.482  -0.413  -0.351  -0.386  -0.332
169   A        -0.124  -0.098  -0.084  -0.006   0.043   0.050  -0.351  -0.312  -0.297
170   L        -0.124  -0.150  -0.108  -0.329  -0.388  -0.340  -0.351  -0.386  -0.332
171   H        -0.124  -0.102  -0.083  -0.274  -0.231  -0.216  -0.351  -0.317  -0.297
172   D        -0.668  -0.639  -0.630  -0.846  -0.773  -0.768  -0.719  -0.683  -0.651
173   N        -1.101  -1.035  -1.056  -1.089  -0.996  -1.016  -0.930  -0.857  -0.855
174   I        -0.504  -0.578  -0.597  -0.584  -0.714  -0.730  -0.509  -0.595  -0.606
175   M        -1.101  -1.137  -1.084  -0.999  -1.058  -0.944  -0.930  -0.956  -0.881
176   E        -0.668  -0.671  -0.648  -0.655  -0.662  -0.596  -0.719  -0.717  -0.669
177   E        -0.504  -0.433  -0.537  -0.505  -0.397  -0.552  -0.509  -0.415  -0.535
178   I        -1.534  -1.521  -1.455  -1.378  -1.360  -1.253  -1.141  -1.121  -1.034
179   -        -1.192  -1.181  -1.113  -1.347  -1.330  -1.222  -1.014  -0.996  -0.907
180   -        -1.192  -1.181  -1.113  -1.002  -1.000  -0.877  -1.014  -0.996  -0.907
181   -        -1.192  -1.181  -1.113  -1.061  -1.066  -0.936  -1.014  -0.996  -0.907
182   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
183   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
184   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
185   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
186   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
187   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
188   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
189   E        -1.192  -1.186  -1.113  -1.187  -1.180  -1.062  -1.014  -1.000  -0.907
190   G        -1.192  -1.186  -1.113  -1.187  -1.175  -1.062  -1.014  -1.000  -0.907
191   P        -0.673  -0.678  -0.654  -0.449  -0.461  -0.428  -0.711  -0.712  -0.672
192   K        -0.673  -0.625  -0.653  -0.648  -0.558  -0.641  -0.711  -0.649  -0.671
193   D        -0.673  -0.682  -0.656  -0.647  -0.657  -0.633  -0.711  -0.716  -0.674
194   A        -0.673  -0.625  -0.653  -0.460  -0.377  -0.430  -0.711  -0.649  -0.671
195   N         0.563   0.561   0.619   0.465   0.450   0.547   0.199   0.184   0.262
196   K        -0.673  -0.661  -0.641  -0.601  -0.587  -0.563  -0.711  -0.692  -0.657
197   F         0.563   0.567   0.616   0.573   0.572   0.646   0.199   0.196   0.257
198   H        -1.101  -1.110  -1.065  -0.781  -0.772  -0.697  -0.930  -0.933  -0.863
199   V         0.980   0.985   0.857   1.061   1.075   0.883   0.966   0.971   0.723
200   T         0.525   0.541   0.607   0.249   0.269   0.378   0.123   0.145   0.238
201   A         1.824   1.851   1.908   2.061   2.101   2.192   2.019   2.058   2.147
202   L         0.631   0.689   0.682   0.367   0.484   0.425   0.334   0.437   0.390
203   G         1.824   1.851   1.908   1.898   1.944   2.029   2.019   2.058   2.147
204   G         1.824   1.851   1.908   1.898   1.944   2.029   2.019   2.058   2.147
205   T         1.824   1.851   1.908   1.922   1.961   2.053   2.019   2.058   2.147
206   F         1.824   1.851   1.908   2.023   2.065   2.154   2.019   2.058   2.147
207   D         1.824   1.851   1.908   1.946   1.989   2.077   2.019   2.058   2.147
208   H         1.824   1.851   1.908   2.075   2.119   2.207   2.019   2.058   2.147
209   I         0.631   0.680   0.675   0.188   0.271   0.240   0.334   0.418   0.375
210   H         1.824   1.851   1.908   2.075   2.119   2.207   2.019   2.058   2.147
211   D         0.980   0.887   0.842   1.137   1.005   0.924   0.966   0.802   0.697
212   G         1.824   1.851   1.908   1.898   1.944   2.029   2.019   2.058   2.147
213   H         1.824   1.851   1.908   2.075   2.119   2.207   2.019   2.058   2.147
214   K         1.824   1.851   1.908   1.828   1.865   1.959   2.019   2.058   2.147
215   I         0.980   0.887   0.842   0.913   0.773   0.705   0.966   0.802   0.697
216   L         1.824   1.851   1.908   1.616   1.657   1.747   2.019   2.058   2.147
217   L         1.824   1.851   1.908   1.616   1.657   1.747   2.019   2.058   2.147
218   S         0.980   0.887   0.842   0.973   0.839   0.773   0.966   0.802   0.697
219   V        -0.071  -0.092  -0.084  -0.249  -0.303  -0.266  -0.298  -0.330  -0.309
220   S         0.198   0.131   0.046   0.460   0.353   0.196   0.123   0.023  -0.107
221   T        -1.101  -1.137  -1.084  -1.119  -1.156  -1.081  -0.930  -0.956  -0.881
222   F         0.198   0.179   0.057   0.544   0.523   0.357   0.123   0.088  -0.090
223   I        -0.071  -0.116  -0.069  -0.442  -0.486  -0.413  -0.298  -0.346  -0.285
224   T         0.980   0.887   0.842   1.122   0.989   0.915   0.966   0.802   0.697
225   S         0.198   0.161   0.055   0.192   0.127  -0.031   0.123   0.064  -0.094
226   Q        -1.101  -1.123  -1.079  -0.931  -0.975  -0.911  -0.930  -0.944  -0.877
227   R        -0.668  -0.703  -0.642  -0.670  -0.733  -0.632  -0.719  -0.747  -0.663
228   L         0.631   0.602   0.639   0.254   0.200   0.253   0.334   0.267   0.304
229   I         1.824   1.851   1.908   1.720   1.754   1.851   2.019   2.058   2.147
230   C        -0.071  -0.060  -0.070  -0.239  -0.231  -0.206  -0.298  -0.286  -0.290
231   G         1.824   1.851   1.908   1.898   1.944   2.029   2.019   2.058   2.147
232   I        -0.071  -0.036  -0.066  -0.391  -0.340  -0.396  -0.298  -0.258  -0.283
233   T         0.980   0.887   0.842   1.096   0.954   0.872   0.966   0.802   0.697
234   C        -0.504  -0.394  -0.552  -0.301  -0.130  -0.361  -0.509  -0.366  -0.554
235   D        -1.101  -1.044  -1.055  -0.947  -0.850  -0.877  -0.930  -0.866  -0.854
236   E         0.198   0.199   0.054   0.218   0.218  -0.011   0.123   0.126  -0.095
237   L         1.824   1.851   1.908   1.616   1.657   1.747   2.019   2.058   2.147
238   L         1.824   1.851   1.908   1.616   1.657   1.747   2.019   2.058   2.147
239   Q        -1.101  -1.116  -1.069  -1.024  -1.066  -0.971  -0.930  -0.938  -0.867
240   N         0.980   0.887   0.842   1.099   0.959   0.883   0.966   0.802   0.697
241   K         1.824   1.851   1.908   1.828   1.865   1.959   2.019   2.058   2.147
242   K         0.198   0.161   0.055   0.275   0.208   0.060   0.123   0.064  -0.094
243   Y        -0.504  -0.544  -0.572  -0.148  -0.205  -0.240  -0.509  -0.555  -0.577
244   K         0.198   0.276   0.091   0.254   0.361   0.088   0.123   0.236  -0.040
245   E         0.198   0.245   0.072   0.241   0.303   0.052   0.123   0.192  -0.068
246   L        -0.668  -0.666  -0.638  -0.734  -0.706  -0.657  -0.719  -0.709  -0.659
247   I         0.980   1.017   0.863   0.780   0.836   0.591   0.966   1.024   0.735
248   E         0.980   0.985   0.857   1.023   1.033   0.857   0.966   0.971   0.723
249   P        -1.101  -1.114  -1.077  -0.893  -0.923  -0.875  -0.930  -0.936  -0.875
250   Y        -0.071  -0.129  -0.073  -0.001  -0.099  -0.017  -0.298  -0.366  -0.294
251   D        -1.101  -1.116  -1.069  -1.063  -1.069  -1.005  -0.930  -0.938  -0.867
252   T        -1.534  -1.521  -1.455  -1.367  -1.342  -1.243  -1.141  -1.121  -1.034
253   R         1.824   1.851   1.908   2.014   2.059   2.146   2.019   2.058   2.147
254   C        -0.668  -0.680  -0.649  -0.514  -0.542  -0.501  -0.719  -0.725  -0.670
255   R        -1.101  -1.110  -1.065  -1.026  -1.062  -0.974  -0.930  -0.933  -0.863
256   H        -1.534  -1.521  -1.455  -1.416  -1.407  -1.291  -1.141  -1.121  -1.034
257   V         1.824   1.851   1.908   1.856   1.899   1.987   2.019   2.058   2.147
258   H        -1.101  -1.078  -1.076  -1.159  -1.144  -1.107  -0.930  -0.902  -0.874
259   Q        -1.101  -1.086  -1.062  -0.977  -0.945  -0.928  -0.930  -0.910  -0.861
260   F         0.980   0.999   0.865   1.248   1.282   1.092   0.966   0.994   0.739
261   I         0.631   0.649   0.653   0.188   0.213   0.196   0.334   0.359   0.332
262   K        -0.668  -0.709  -0.643  -0.586  -0.628  -0.525  -0.719  -0.753  -0.664
263   L         0.198   0.116   0.047  -0.003  -0.137  -0.254   0.123   0.002  -0.105
264   L         0.198   0.116   0.047  -0.008  -0.144  -0.261   0.123   0.002  -0.105
265   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
266   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
267   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
268   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
269   K         0.198   0.199   0.054   0.269   0.268   0.049   0.123   0.126  -0.095
270   P        -0.504  -0.578  -0.597  -0.298  -0.434  -0.488  -0.509  -0.595  -0.606
271   D        -0.668  -0.660  -0.636  -0.749  -0.713  -0.683  -0.719  -0.701  -0.657
272   L         0.525   0.549   0.611  -0.017   0.026   0.124   0.123   0.161   0.246
273   S        -0.504  -0.567  -0.580  -0.452  -0.553  -0.573  -0.509  -0.582  -0.587
274   V        -1.101  -1.078  -1.076  -0.798  -0.748  -0.759  -0.930  -0.902  -0.874
275   E         0.980   0.887   0.842   1.025   0.899   0.837   0.966   0.802   0.697
276   L        -0.071  -0.060  -0.070  -0.391  -0.379  -0.404  -0.298  -0.286  -0.290
277   V        -0.504  -0.470  -0.561  -0.403  -0.338  -0.488  -0.509  -0.461  -0.564
278   P        -1.101  -1.137  -1.084  -0.802  -0.869  -0.783  -0.930  -0.956  -0.881
279   L         0.980   1.017   0.863   0.864   0.915   0.661   0.966   1.024   0.735
280   R        -0.071  -0.135  -0.087   0.021  -0.063   0.011  -0.298  -0.376  -0.310
281   D         1.824   1.851   1.908   1.946   1.989   2.077   2.019   2.058   2.147
282   V         0.980   0.887   0.842   1.089   0.969   0.905   0.966   0.802   0.697
283   C         0.980   0.887   0.842   1.351   1.225   1.154   0.966   0.802   0.697
284   G         1.824   1.851   1.908   1.898   1.944   2.029   2.019   2.058   2.147
285   P         1.824   1.851   1.908   2.058   2.101   2.190   2.019   2.058   2.147
286   T         1.824   1.851   1.908   1.922   1.961   2.053   2.019   2.058   2.147
287   G         0.980   0.887   0.842   1.063   0.925   0.833   0.966   0.802   0.697
288   K        -0.071  -0.052  -0.068  -0.055  -0.026  -0.049  -0.298  -0.272  -0.283
289   V        -0.071  -0.135  -0.087  -0.255  -0.351  -0.278  -0.298  -0.376  -0.310
290   P        -0.504  -0.578  -0.597  -0.214  -0.326  -0.374  -0.509  -0.595  -0.606
291   E         0.525   0.542   0.607   0.292   0.313   0.418   0.123   0.146   0.239
292   I         1.824   1.851   1.908   1.720   1.754   1.851   2.019   2.058   2.147
293   E        -0.668  -0.630  -0.636  -0.669  -0.603  -0.596  -0.719  -0.672  -0.656
294   C        -0.668  -0.637  -0.635  -0.545  -0.529  -0.493  -0.719  -0.680  -0.656
295   L         1.824   1.851   1.908   1.616   1.657   1.747   2.019   2.058   2.147
296   V         0.198   0.226   0.075   0.184   0.223   0.013   0.123   0.166  -0.063
297   V         0.980   0.985   0.857   1.021   1.033   0.818   0.966   0.971   0.723
298   S         1.824   1.851   1.908   1.767   1.804   1.898   2.019   2.058   2.147
299   R        -0.071  -0.092  -0.084  -0.059  -0.110  -0.090  -0.298  -0.330  -0.309
300   E         1.824   1.851   1.908   1.801   1.838   1.932   2.019   2.058   2.147
301   T         0.980   0.999   0.865   1.096   1.125   0.912   0.966   0.994   0.739
302   V        -1.101  -1.028  -1.056  -1.328  -1.181  -1.278  -0.930  -0.850  -0.856
303   S        -0.668  -0.701  -0.641  -0.785  -0.831  -0.739  -0.719  -0.745  -0.662
304   G         1.824   1.851   1.908   1.898   1.944   2.029   2.019   2.058   2.147
305   A         0.631   0.608   0.638   0.610   0.572   0.614   0.334   0.278   0.301
306   E        -0.504  -0.535  -0.566  -0.496  -0.545  -0.597  -0.509  -0.544  -0.570
307   T        -1.101  -1.078  -1.076  -0.915  -0.857  -0.890  -0.930  -0.902  -0.874
308   V         1.824   1.851   1.908   1.856   1.899   1.987   2.019   2.058   2.147
309   N         0.980   0.887   0.842   1.134   1.006   0.942   0.966   0.802   0.697
310   K         0.980   0.887   0.842   1.009   0.867   0.792   0.966   0.802   0.697
311   T         0.198   0.105   0.039   0.357   0.208   0.107   0.123  -0.014  -0.116
312   R         1.824   1.851   1.908   2.014   2.059   2.146   2.019   2.058   2.147
313   I        -1.534  -1.521  -1.455  -1.528  -1.505  -1.404  -1.141  -1.121  -1.034
314   E        -0.668  -0.672  -0.633  -0.781  -0.792  -0.730  -0.719  -0.719  -0.654
315   K        -0.071  -0.085  -0.071  -0.075  -0.090  -0.048  -0.298  -0.317  -0.292
316   G         1.824   1.851   1.908   1.898   1.944   2.029   2.019   2.058   2.147
317   M        -0.668  -0.664  -0.636  -0.593  -0.605  -0.540  -0.719  -0.707  -0.657
318   S         0.198   0.105   0.039   0.222   0.090  -0.011   0.123  -0.014  -0.116
319   P        -0.504  -0.443  -0.541  -0.483  -0.396  -0.540  -0.509  -0.428  -0.540
320   L         1.824   1.851   1.908   1.616   1.657   1.747   2.019   2.058   2.147
321   A         0.198   0.131   0.046   0.382   0.270   0.141   0.123   0.023  -0.107
322   V         0.631   0.656   0.657   0.351   0.385   0.376   0.334   0.371   0.339
323   H        -0.668  -0.658  -0.633  -0.633  -0.608  -0.558  -0.719  -0.702  -0.654
324   V         0.198   0.105   0.039   0.301   0.175   0.059   0.123  -0.014  -0.116
325   V         0.525   0.549   0.611   0.165   0.193   0.295   0.123   0.161   0.246
326   N         0.198   0.105   0.039   0.336   0.193   0.080   0.123  -0.014  -0.116
327   V         0.980   0.887   0.842   1.001   0.855   0.758   0.966   0.802   0.697
328   L         0.631   0.642   0.662   0.188   0.198   0.214   0.334   0.345   0.350
329   G         0.980   0.887   0.842   1.126   1.007   0.937   0.966   0.802   0.697
330   G         0.198   0.116   0.047   0.378   0.271   0.162   0.123   0.002  -0.105
331   R        -0.504  -0.567  -0.580  -0.207  -0.295  -0.318  -0.509  -0.582  -0.587
332   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
333   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
334   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
335   E         0.980   0.887   0.842   1.023   0.896   0.834   0.966   0.802   0.697
336   E        -0.071  -0.022  -0.041  -0.157  -0.075  -0.091  -0.298  -0.218  -0.244
337   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
338   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
339   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
340   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
341   D         0.631   0.642   0.662   0.586   0.601   0.616   0.334   0.345   0.350
342   G        -0.071  -0.092  -0.084  -0.161  -0.201  -0.193  -0.298  -0.330  -0.309
343   W         0.980   0.887   0.842   1.367   1.234   1.155   0.966   0.802   0.697
344   S        -0.071  -0.081  -0.073  -0.348  -0.385  -0.380  -0.298  -0.316  -0.294
345   E        -0.071  -0.135  -0.087  -0.295  -0.409  -0.341  -0.298  -0.376  -0.310
346   K         1.824   1.851   1.908   1.828   1.865   1.959   2.019   2.058   2.147
347   L        -0.504  -0.484  -0.562  -0.640  -0.617  -0.711  -0.509  -0.485  -0.565
348   S         1.824   1.851   1.908   1.767   1.804   1.898   2.019   2.058   2.147
349   S         1.824   1.851   1.908   1.767   1.804   1.898   2.019   2.058   2.147
350   T         1.824   1.851   1.908   1.922   1.961   2.053   2.019   2.058   2.147
351   E        -0.071  -0.116  -0.069  -0.100  -0.145  -0.081  -0.298  -0.346  -0.285
352   I         0.980   1.053   0.866   0.864   0.968   0.666   0.966   1.083   0.740
353   R         1.824   1.851   1.908   2.014   2.059   2.146   2.019   2.058   2.147
354   R        -0.071  -0.028  -0.050  -0.221  -0.151  -0.172  -0.298  -0.232  -0.259
355   L        -0.668  -0.693  -0.651  -0.650  -0.694  -0.652  -0.719  -0.738  -0.672
356   L        -0.071  -0.027  -0.064  -0.377  -0.323  -0.334  -0.298  -0.242  -0.278
357   K        -0.668  -0.629  -0.638  -0.541  -0.476  -0.505  -0.719  -0.675  -0.659
358   S        -0.668  -0.664  -0.636  -0.848  -0.840  -0.787  -0.719  -0.707  -0.657
359   S        -0.668  -0.709  -0.643  -0.876  -0.955  -0.832  -0.719  -0.753  -0.664
360   A        -0.153  -0.128  -0.102  -0.269  -0.218  -0.167  -0.408  -0.373  -0.331
361   S        -0.153  -0.132  -0.106  -0.349  -0.302  -0.278  -0.408  -0.378  -0.336
362   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
363   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
364   C        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
365   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
366   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
367   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
368   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
369   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
370   C        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
371   V        -0.504  -0.443  -0.541  -0.428  -0.334  -0.480  -0.509  -0.428  -0.540
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P53332
Output conservation file - output/P53332
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
