1     M         1.723   1.725   1.742   2.042   2.047   2.072   1.837   1.840   1.861
2     A         0.119   0.151   0.094   0.145   0.191   0.116  -0.005   0.046  -0.045
3     A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     D        -0.024  -0.023  -0.008  -0.333  -0.331  -0.306  -0.236  -0.234  -0.209
7     N        -0.024  -0.023  -0.008  -0.132  -0.130  -0.105  -0.236  -0.234  -0.209
8     F        -0.024  -0.023  -0.008   0.215   0.217   0.242  -0.236  -0.234  -0.209
9     L         1.723   1.725   1.742   1.590   1.594   1.620   1.837   1.840   1.861
10    Q        -0.024  -0.023  -0.008  -0.044  -0.042  -0.017  -0.236  -0.234  -0.209
11    N        -0.024  -0.023  -0.008  -0.210  -0.208  -0.183  -0.236  -0.234  -0.209
12    I        -0.024  -0.023  -0.008   0.048   0.050   0.075  -0.236  -0.234  -0.209
13    E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
19    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
20    G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
21    Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
22    A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
23    M        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
24    D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
25    L         1.723   1.725   1.742   1.590   1.594   1.620   1.837   1.840   1.861
26    S         1.723   1.725   1.742   1.648   1.652   1.678   1.837   1.840   1.861
27    P         1.723   1.725   1.742   1.983   1.988   2.014   1.837   1.840   1.861
28    N        -0.024  -0.023  -0.008  -0.210  -0.208  -0.183  -0.236  -0.234  -0.209
29    R        -0.024  -0.023  -0.008   0.019   0.021   0.047  -0.236  -0.234  -0.209
30    S        -0.024  -0.023  -0.008  -0.050  -0.048  -0.022  -0.236  -0.234  -0.209
31    S        -0.024  -0.023  -0.008  -0.097  -0.094  -0.069  -0.236  -0.234  -0.209
32    S         1.723   1.725   1.742   1.648   1.652   1.678   1.837   1.840   1.861
33    E        -0.024  -0.023  -0.008  -0.376  -0.375  -0.349  -0.236  -0.234  -0.209
34    S         1.723   1.725   1.742   1.648   1.652   1.678   1.837   1.840   1.861
35    D         1.723   1.725   1.742   1.705   1.709   1.735   1.837   1.840   1.861
36    S         1.723   1.725   1.742   1.648   1.652   1.678   1.837   1.840   1.861
37    S         1.723   1.725   1.742   1.648   1.652   1.678   1.837   1.840   1.861
38    I         1.723   1.725   1.742   1.802   1.806   1.832   1.837   1.840   1.861
39    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
40    L        -0.024  -0.023  -0.008  -0.295  -0.293  -0.268  -0.236  -0.234  -0.209
41    M        -0.024  -0.023  -0.008  -0.050  -0.048  -0.022  -0.236  -0.234  -0.209
42    N         0.119   0.112   0.087   0.016   0.002  -0.049  -0.005  -0.016  -0.056
43    V        -1.046  -1.044  -1.031  -0.855  -0.853  -0.829  -0.927  -0.923  -0.900
44    N         0.119   0.151   0.094   0.081   0.130   0.039  -0.005   0.046  -0.045
45    D        -1.046  -1.044  -1.031  -0.880  -0.876  -0.854  -0.927  -0.923  -0.900
46    I         0.119   0.100   0.072   0.264   0.236   0.201  -0.005  -0.036  -0.080
47    K        -1.046  -1.044  -1.031  -1.005  -0.995  -0.979  -0.927  -0.923  -0.900
48    T         0.119   0.100   0.072   0.283   0.250   0.199  -0.005  -0.036  -0.080
49    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
50    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
51    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
52    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
53    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
54    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
55    L        -0.024  -0.023  -0.008  -0.085  -0.083  -0.058  -0.236  -0.234  -0.209
56    R         1.723   1.725   1.742   1.810   1.814   1.840   1.837   1.840   1.861
57    L        -0.024  -0.023  -0.008  -0.222  -0.220  -0.195  -0.236  -0.234  -0.209
58    D         1.723   1.725   1.742   1.705   1.709   1.735   1.837   1.840   1.861
59    V        -0.024  -0.023  -0.008  -0.021  -0.019   0.006  -0.236  -0.234  -0.209
60    A        -0.024  -0.023  -0.008   0.065   0.067   0.092  -0.236  -0.234  -0.209
61    P        -0.024  -0.023  -0.008  -0.009  -0.007   0.018  -0.236  -0.234  -0.209
62    E        -0.024  -0.023  -0.008  -0.295  -0.293  -0.268  -0.236  -0.234  -0.209
63    A        -0.024  -0.023  -0.008   0.065   0.067   0.092  -0.236  -0.234  -0.209
64    K        -0.024  -0.023  -0.008  -0.156  -0.154  -0.129  -0.236  -0.234  -0.209
65    S         1.723   1.725   1.742   1.657   1.662   1.687   1.837   1.840   1.861
66    T         0.119   0.151   0.094   0.101   0.150   0.067  -0.005   0.046  -0.045
67    Q        -1.046  -1.044  -1.031  -0.781  -0.780  -0.754  -0.927  -0.923  -0.900
68    S         0.119   0.100   0.072  -0.076  -0.110  -0.169  -0.005  -0.036  -0.080
69    K        -1.046  -1.044  -1.031  -1.305  -1.296  -1.279  -0.927  -0.923  -0.900
70    K        -1.046  -1.044  -1.031  -0.964  -0.950  -0.938  -0.927  -0.923  -0.900
71    S        -1.046  -1.044  -1.031  -1.272  -1.272  -1.246  -0.927  -0.923  -0.900
72    L        -1.046  -1.044  -1.031  -1.009  -0.997  -0.983  -0.927  -0.923  -0.900
73    F        -1.046  -1.044  -1.031  -0.694  -0.694  -0.668  -0.927  -0.923  -0.900
74    Y         0.119   0.112   0.087   0.438   0.428   0.387  -0.005  -0.016  -0.056
75    E        -1.046  -1.044  -1.031  -0.998  -0.981  -0.972  -0.927  -0.923  -0.900
76    N        -1.046  -1.044  -1.031  -1.211  -1.213  -1.185  -0.927  -0.923  -0.900
77    S         0.119   0.100   0.072  -0.105  -0.140  -0.202  -0.005  -0.036  -0.080
78    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
79    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
80    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
81    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
82    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
83    D         1.723   1.725   1.742   1.724   1.723   1.754   1.837   1.840   1.861
84    D         1.723   1.725   1.742   1.724   1.723   1.754   1.837   1.840   1.861
85    A        -1.046  -1.044  -1.031  -1.032  -1.041  -1.006  -0.927  -0.923  -0.900
86    E         0.119   0.112   0.087  -0.041  -0.047  -0.078  -0.005  -0.016  -0.056
87    E        -1.046  -1.044  -1.031  -0.998  -0.977  -0.972  -0.927  -0.923  -0.900
88    G         0.119   0.112   0.087   0.341   0.330   0.281  -0.005  -0.016  -0.056
89    E        -1.046  -1.044  -1.031  -1.116  -1.105  -1.090  -0.927  -0.923  -0.900
90    I        -1.046  -1.044  -1.031  -1.163  -1.166  -1.137  -0.927  -0.923  -0.900
91    E        -1.046  -1.044  -1.031  -0.819  -0.796  -0.793  -0.927  -0.923  -0.900
92    E        -1.046  -1.044  -1.031  -1.187  -1.170  -1.161  -0.927  -0.923  -0.900
93    R         0.119   0.112   0.087   0.229   0.219   0.188  -0.005  -0.016  -0.056
94    T        -1.046  -1.044  -1.031  -0.898  -0.901  -0.872  -0.927  -0.923  -0.900
95    N         0.119   0.100   0.072   0.095   0.058   0.011  -0.005  -0.036  -0.080
96    K        -1.046  -1.044  -1.031  -1.372  -1.363  -1.347  -0.927  -0.923  -0.900
97    E         0.119   0.100   0.072  -0.152  -0.182  -0.226  -0.005  -0.036  -0.080
98    E        -1.046  -1.044  -1.031  -1.074  -1.059  -1.048  -0.927  -0.923  -0.900
99    G        -1.046  -1.044  -1.031  -0.920  -0.925  -0.894  -0.927  -0.923  -0.900
100   Q         0.119   0.112   0.087   0.191   0.179   0.129  -0.005  -0.016  -0.056
101   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
102   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
103   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
104   Y        -1.046  -1.044  -1.031  -0.891  -0.898  -0.865  -0.927  -0.923  -0.900
105   H        -1.046  -1.044  -1.031  -0.742  -0.748  -0.716  -0.927  -0.923  -0.900
106   H        -1.046  -1.044  -1.031  -0.691  -0.693  -0.664  -0.927  -0.923  -0.900
107   K        -1.046  -1.044  -1.031  -1.039  -1.031  -1.013  -0.927  -0.923  -0.900
108   G         0.119   0.151   0.094   0.200   0.242   0.168  -0.005   0.046  -0.045
109   S         0.119   0.112   0.087  -0.105  -0.115  -0.172  -0.005  -0.016  -0.056
110   K        -1.046  -1.044  -1.031  -0.809  -0.791  -0.782  -0.927  -0.923  -0.900
111   Q        -1.046  -1.044  -1.031  -0.920  -0.917  -0.894  -0.927  -0.923  -0.900
112   L        -1.046  -1.044  -1.031  -0.869  -0.853  -0.843  -0.927  -0.923  -0.900
113   R         0.119   0.100   0.072   0.095   0.058   0.011  -0.005  -0.036  -0.080
114   F         0.119   0.100   0.072   0.362   0.327   0.275  -0.005  -0.036  -0.080
115   E        -1.046  -1.044  -1.031  -0.987  -0.968  -0.961  -0.927  -0.923  -0.900
116   V         0.119   0.151   0.094   0.355   0.406   0.317  -0.005   0.046  -0.045
117   G        -1.046  -1.044  -1.031  -0.570  -0.566  -0.543  -0.927  -0.923  -0.900
118   K        -1.046  -1.044  -1.031  -0.976  -0.961  -0.949  -0.927  -0.923  -0.900
119   E        -1.046  -1.044  -1.031  -1.013  -0.998  -0.987  -0.927  -0.923  -0.900
120   S        -1.046  -1.044  -1.031  -1.081  -1.075  -1.055  -0.927  -0.923  -0.900
121   T        -0.024  -0.023  -0.008   0.019   0.021   0.047  -0.236  -0.234  -0.209
122   G        -0.024  -0.023  -0.008  -0.120  -0.118  -0.093  -0.236  -0.234  -0.209
123   K        -0.024  -0.023  -0.008  -0.252  -0.250  -0.225  -0.236  -0.234  -0.209
124   L        -0.024  -0.023  -0.008  -0.103  -0.100  -0.075  -0.236  -0.234  -0.209
125   Q        -0.024  -0.023  -0.008   0.031   0.033   0.058  -0.236  -0.234  -0.209
126   S        -0.024  -0.023  -0.008  -0.033  -0.030  -0.005  -0.236  -0.234  -0.209
127   H        -0.024  -0.023  -0.008   0.231   0.233   0.259  -0.236  -0.234  -0.209
128   L        -0.024  -0.023  -0.008  -0.228  -0.226  -0.201  -0.236  -0.234  -0.209
129   S        -1.046  -1.044  -1.031  -0.920  -0.911  -0.894  -0.927  -0.923  -0.900
130   D         0.119   0.100   0.072  -0.041  -0.082  -0.141  -0.005  -0.036  -0.080
131   G        -1.046  -1.044  -1.031  -1.028  -1.035  -1.002  -0.927  -0.923  -0.900
132   S         0.119   0.100   0.072   0.139   0.115   0.080  -0.005  -0.036  -0.080
133   A        -1.046  -1.044  -1.031  -0.760  -0.758  -0.733  -0.927  -0.923  -0.900
134   T        -1.046  -1.044  -1.031  -0.990  -0.996  -0.964  -0.927  -0.923  -0.900
135   S        -1.046  -1.044  -1.031  -1.272  -1.272  -1.246  -0.927  -0.923  -0.900
136   G         0.119   0.151   0.094  -0.012   0.034  -0.038  -0.005   0.046  -0.045
137   E        -1.046  -1.044  -1.031  -1.036  -1.019  -1.010  -0.927  -0.923  -0.900
138   G        -1.046  -1.044  -1.031  -0.781  -0.784  -0.754  -0.927  -0.923  -0.900
139   N         0.119   0.112   0.087  -0.012  -0.026  -0.081  -0.005  -0.016  -0.056
140   V         0.119   0.112   0.087   0.172   0.160   0.099  -0.005  -0.016  -0.056
141   R        -1.046  -1.044  -1.031  -1.081  -1.081  -1.055  -0.927  -0.923  -0.900
142   P         1.723   1.725   1.742   1.996   2.000   2.026   1.837   1.840   1.861
143   W         1.723   1.725   1.742   2.144   2.149   2.175   1.837   1.840   1.861
144   E        -1.046  -1.044  -1.031  -1.116  -1.105  -1.090  -0.927  -0.923  -0.900
145   F         1.723   1.725   1.742   2.013   2.017   2.043   1.837   1.840   1.861
146   R        -1.046  -1.044  -1.031  -0.976  -0.974  -0.949  -0.927  -0.923  -0.900
147   K         0.119   0.100   0.072  -0.055  -0.086  -0.131  -0.005  -0.036  -0.080
148   V         0.119   0.151   0.094   0.016   0.062  -0.014  -0.005   0.046  -0.045
149   I         1.723   1.725   1.742   1.790   1.793   1.820   1.837   1.840   1.861
150   Q         0.119   0.151   0.094   0.172   0.221   0.135  -0.005   0.046  -0.045
151   A        -1.046  -1.044  -1.031  -0.961  -0.969  -0.935  -0.927  -0.923  -0.900
152   E         0.119   0.100   0.072  -0.009  -0.032  -0.062  -0.005  -0.036  -0.080
153   Y         0.119   0.112   0.087   0.479   0.470   0.432  -0.005  -0.016  -0.056
154   R         0.119   0.151   0.094  -0.055  -0.003  -0.095  -0.005   0.046  -0.045
155   E         0.119   0.112   0.087  -0.137  -0.145  -0.185  -0.005  -0.016  -0.056
156   R         0.119   0.100   0.072   0.172   0.141   0.101  -0.005  -0.036  -0.080
157   L         1.723   1.725   1.742   1.552   1.556   1.581   1.837   1.840   1.861
158   P         1.723   1.725   1.742   1.996   2.000   2.026   1.837   1.840   1.861
159   R        -1.046  -1.044  -1.031  -1.039  -1.041  -1.013  -0.927  -0.923  -0.900
160   N         0.119   0.100   0.072   0.189   0.159   0.120  -0.005  -0.036  -0.080
161   Y         1.723   1.725   1.742   2.019   2.023   2.049   1.837   1.840   1.861
162   E        -1.046  -1.044  -1.031  -1.097  -1.081  -1.071  -0.927  -0.923  -0.900
163   L         0.119   0.100   0.072  -0.061  -0.091  -0.133  -0.005  -0.036  -0.080
164   K         0.119   0.100   0.072  -0.055  -0.086  -0.131  -0.005  -0.036  -0.080
165   H        -1.046  -1.044  -1.031  -0.841  -0.846  -0.814  -0.927  -0.923  -0.900
166   W         1.723   1.725   1.742   2.144   2.149   2.175   1.837   1.840   1.861
167   K         0.119   0.112   0.087  -0.055  -0.065  -0.106  -0.005  -0.016  -0.056
168   K         0.119   0.100   0.072  -0.055  -0.086  -0.131  -0.005  -0.036  -0.080
169   P         1.723   1.725   1.742   1.996   2.000   2.026   1.837   1.840   1.861
170   S         1.723   1.725   1.742   1.657   1.662   1.687   1.837   1.840   1.861
171   K         0.119   0.112   0.087  -0.055  -0.065  -0.106  -0.005  -0.016  -0.056
172   I         0.119   0.100   0.072   0.128   0.092   0.044  -0.005  -0.036  -0.080
173   M         0.119   0.112   0.087   0.286   0.273   0.214  -0.005  -0.016  -0.056
174   I        -1.046  -1.044  -1.031  -0.998  -0.999  -0.972  -0.927  -0.923  -0.900
175   G        -1.046  -1.044  -1.031  -0.777  -0.779  -0.751  -0.927  -0.923  -0.900
176   S         0.119   0.100   0.072   0.019  -0.012  -0.059  -0.005  -0.036  -0.080
177   I        -1.046  -1.044  -1.031  -0.722  -0.713  -0.695  -0.927  -0.923  -0.900
178   L        -1.046  -1.044  -1.031  -0.939  -0.925  -0.912  -0.927  -0.923  -0.900
179   R        -1.046  -1.044  -1.031  -0.953  -0.953  -0.927  -0.927  -0.923  -0.900
180   L         1.723   1.725   1.742   1.552   1.556   1.581   1.837   1.840   1.861
181   L         0.119   0.100   0.072  -0.061  -0.091  -0.133  -0.005  -0.036  -0.080
182   E         1.723   1.725   1.742   1.489   1.496   1.519   1.837   1.840   1.861
183   T         0.119   0.100   0.072   0.267   0.233   0.180  -0.005  -0.036  -0.080
184   N         1.723   1.725   1.742   1.754   1.757   1.784   1.837   1.840   1.861
185   T        -1.046  -1.044  -1.031  -0.950  -0.951  -0.923  -0.927  -0.923  -0.900
186   V        -1.046  -1.044  -1.031  -0.891  -0.895  -0.865  -0.927  -0.923  -0.900
187   S        -1.046  -1.044  -1.031  -1.211  -1.209  -1.185  -0.927  -0.923  -0.900
188   A         0.119   0.112   0.087   0.310   0.298   0.244  -0.005  -0.016  -0.056
189   L        -1.046  -1.044  -1.031  -1.081  -1.071  -1.055  -0.927  -0.923  -0.900
190   D         0.119   0.100   0.072  -0.041  -0.082  -0.141  -0.005  -0.036  -0.080
191   S        -1.046  -1.044  -1.031  -1.227  -1.224  -1.201  -0.927  -0.923  -0.900
192   V         1.723   1.725   1.742   1.949   1.953   1.980   1.837   1.840   1.861
193   F         1.723   1.725   1.742   2.013   2.017   2.043   1.837   1.840   1.861
194   E         0.119   0.100   0.072  -0.223  -0.254  -0.309  -0.005  -0.036  -0.080
195   K         0.119   0.100   0.072   0.011  -0.017  -0.055  -0.005  -0.036  -0.080
196   Y         1.723   1.725   1.742   2.019   2.023   2.049   1.837   1.840   1.861
197   E        -1.046  -1.044  -1.031  -1.017  -0.998  -0.991  -0.927  -0.923  -0.900
198   K        -1.046  -1.044  -1.031  -1.062  -1.053  -1.036  -0.927  -0.923  -0.900
199   E         1.723   1.725   1.742   1.489   1.496   1.519   1.837   1.840   1.861
200   M         0.119   0.151   0.094   0.061   0.105   0.036  -0.005   0.046  -0.045
201   N         0.119   0.112   0.087   0.243   0.233   0.203  -0.005  -0.016  -0.056
202   Q         0.119   0.112   0.087   0.235   0.222   0.177  -0.005  -0.016  -0.056
203   M         0.119   0.151   0.094   0.061   0.105   0.036  -0.005   0.046  -0.045
204   T        -0.024  -0.023  -0.008  -0.199  -0.197  -0.172  -0.236  -0.234  -0.209
205   H        -1.046  -1.044  -1.031  -0.684  -0.682  -0.657  -0.927  -0.923  -0.900
206   G         0.119   0.100   0.072   0.448   0.419   0.375  -0.005  -0.036  -0.080
207   D         0.119   0.112   0.087  -0.001  -0.017  -0.064  -0.005  -0.016  -0.056
208   N        -1.046  -1.044  -1.031  -1.081  -1.081  -1.055  -0.927  -0.923  -0.900
209   N        -1.046  -1.044  -1.031  -1.097  -1.097  -1.071  -0.927  -0.923  -0.900
210   E         1.723   1.725   1.742   1.489   1.496   1.519   1.837   1.840   1.861
211   V        -1.046  -1.044  -1.031  -0.795  -0.794  -0.768  -0.927  -0.923  -0.900
212   K        -1.046  -1.044  -1.031  -1.124  -1.108  -1.098  -0.927  -0.923  -0.900
213   R        -1.046  -1.044  -1.031  -1.264  -1.266  -1.238  -0.927  -0.923  -0.900
214   I         0.119   0.100   0.072   0.050   0.012  -0.047  -0.005  -0.036  -0.080
215   Y         0.119   0.151   0.094   0.073   0.118   0.045  -0.005   0.046  -0.045
216   S        -1.046  -1.044  -1.031  -1.272  -1.268  -1.246  -0.927  -0.923  -0.900
217   K        -1.046  -1.044  -1.031  -1.215  -1.210  -1.189  -0.927  -0.923  -0.900
218   K         0.119   0.100   0.072  -0.152  -0.186  -0.242  -0.005  -0.036  -0.080
219   E         1.723   1.725   1.742   1.489   1.496   1.519   1.837   1.840   1.861
220   R        -1.046  -1.044  -1.031  -1.132  -1.131  -1.106  -0.927  -0.923  -0.900
221   L        -1.046  -1.044  -1.031  -1.070  -1.060  -1.044  -0.927  -0.923  -0.900
222   L         0.119   0.100   0.072   0.016  -0.010  -0.044  -0.005  -0.036  -0.080
223   E        -1.046  -1.044  -1.031  -0.859  -0.837  -0.832  -0.927  -0.923  -0.900
224   I         0.119   0.151   0.094   0.098   0.146   0.057  -0.005   0.046  -0.045
225   I         0.119   0.100   0.072   0.221   0.192   0.151  -0.005  -0.036  -0.080
226   L         0.119   0.100   0.072   0.005  -0.022  -0.057  -0.005  -0.036  -0.080
227   T        -1.046  -1.044  -1.031  -0.674  -0.668  -0.647  -0.927  -0.923  -0.900
228   K        -1.046  -1.044  -1.031  -1.132  -1.123  -1.106  -0.927  -0.923  -0.900
229   I         1.723   1.725   1.742   1.790   1.793   1.820   1.837   1.840   1.861
230   K         0.119   0.112   0.087  -0.181  -0.192  -0.247  -0.005  -0.016  -0.056
231   K         1.723   1.725   1.742   1.577   1.582   1.606   1.837   1.840   1.861
232   K         0.119   0.100   0.072  -0.055  -0.086  -0.131  -0.005  -0.036  -0.080
233   L         1.723   1.725   1.742   1.552   1.556   1.581   1.837   1.840   1.861
234   R         0.119   0.100   0.072   0.028  -0.009  -0.067  -0.005  -0.036  -0.080
235   Q        -1.046  -1.044  -1.031  -0.777  -0.777  -0.751  -0.927  -0.923  -0.900
236   A        -1.046  -1.044  -1.031  -0.809  -0.809  -0.782  -0.927  -0.923  -0.900
237   K         1.723   1.725   1.742   1.577   1.582   1.606   1.837   1.840   1.861
238   F         0.119   0.100   0.072   0.433   0.401   0.356  -0.005  -0.036  -0.080
239   P         1.723   1.725   1.742   1.996   2.000   2.026   1.837   1.840   1.861
240   S         1.723   1.725   1.742   1.657   1.662   1.687   1.837   1.840   1.861
241   R         0.119   0.100   0.072   0.028  -0.009  -0.067  -0.005  -0.036  -0.080
242   I         0.119   0.112   0.087   0.050   0.037  -0.016  -0.005  -0.016  -0.056
243   S        -1.046  -1.044  -1.031  -0.732  -0.714  -0.705  -0.927  -0.923  -0.900
244   E         0.119   0.100   0.072  -0.041  -0.064  -0.098  -0.005  -0.036  -0.080
245   R        -1.046  -1.044  -1.031  -1.039  -1.041  -1.013  -0.927  -0.923  -0.900
246   D         0.119   0.100   0.072   0.081   0.044   0.001  -0.005  -0.036  -0.080
247   L         1.723   1.725   1.742   1.552   1.556   1.581   1.837   1.840   1.861
248   D         0.119   0.151   0.094   0.095   0.147   0.051  -0.005   0.046  -0.045
249   I         0.119   0.100   0.072   0.275   0.248   0.213  -0.005  -0.036  -0.080
250   E         1.723   1.725   1.742   1.489   1.496   1.519   1.837   1.840   1.861
251   Y         1.723   1.725   1.742   2.019   2.023   2.049   1.837   1.840   1.861
252   I         1.723   1.725   1.742   1.790   1.793   1.820   1.837   1.840   1.861
253   Y         1.723   1.725   1.742   2.019   2.023   2.049   1.837   1.840   1.861
254   S        -1.046  -1.044  -1.031  -1.074  -1.060  -1.048  -0.927  -0.923  -0.900
255   K         1.723   1.725   1.742   1.577   1.582   1.606   1.837   1.840   1.861
256   R         0.119   0.100   0.072   0.227   0.199   0.163  -0.005  -0.036  -0.080
257   Q        -1.046  -1.044  -1.031  -1.097  -1.103  -1.071  -0.927  -0.923  -0.900
258   F         0.119   0.100   0.072   0.304   0.267   0.208  -0.005  -0.036  -0.080
259   I         0.119   0.112   0.087   0.050   0.037  -0.016  -0.005  -0.016  -0.056
260   Q         0.119   0.100   0.072   0.156   0.118   0.057  -0.005  -0.036  -0.080
261   N        -1.046  -1.044  -1.031  -1.305  -1.306  -1.279  -0.927  -0.923  -0.900
262   R         1.723   1.725   1.742   1.754   1.757   1.784   1.837   1.840   1.861
263   Y         1.723   1.725   1.742   2.019   2.023   2.049   1.837   1.840   1.861
264   S        -1.046  -1.044  -1.031  -1.066  -1.060  -1.040  -0.927  -0.923  -0.900
265   Q         0.119   0.100   0.072   0.191   0.156   0.099  -0.005  -0.036  -0.080
266   E         1.723   1.725   1.742   1.489   1.496   1.519   1.837   1.840   1.861
267   L         1.723   1.725   1.742   1.552   1.556   1.581   1.837   1.840   1.861
268   Q        -1.046  -1.044  -1.031  -0.953  -0.958  -0.927  -0.927  -0.923  -0.900
269   N        -1.046  -1.044  -1.031  -1.132  -1.131  -1.106  -0.927  -0.923  -0.900
270   N         0.119   0.151   0.094   0.352   0.409   0.304  -0.005   0.046  -0.045
271   E         1.723   1.725   1.742   1.489   1.496   1.519   1.837   1.840   1.861
272   R        -1.046  -1.044  -1.031  -0.834  -0.825  -0.807  -0.927  -0.923  -0.900
273   L         0.119   0.100   0.072  -0.061  -0.091  -0.133  -0.005  -0.036  -0.080
274   E         1.723   1.725   1.742   1.489   1.496   1.519   1.837   1.840   1.861
275   A        -1.046  -1.044  -1.031  -0.774  -0.778  -0.747  -0.927  -0.923  -0.900
276   I        -1.046  -1.044  -1.031  -1.074  -1.069  -1.048  -0.927  -0.923  -0.900
277   L         0.119   0.112   0.087  -0.061  -0.071  -0.109  -0.005  -0.016  -0.056
278   S        -1.046  -1.044  -1.031  -0.891  -0.881  -0.865  -0.927  -0.923  -0.900
279   R         0.119   0.112   0.087   0.028   0.015  -0.037  -0.005  -0.016  -0.056
280   E         1.723   1.725   1.742   1.489   1.496   1.519   1.837   1.840   1.861
281   Q        -1.046  -1.044  -1.031  -1.097  -1.103  -1.071  -0.927  -0.923  -0.900
282   N        -1.046  -1.044  -1.031  -1.305  -1.308  -1.279  -0.927  -0.923  -0.900
283   L         0.119   0.100   0.072   0.061   0.038   0.008  -0.005  -0.036  -0.080
284   L         1.723   1.725   1.742   1.552   1.556   1.581   1.837   1.840   1.861
285   E        -1.046  -1.044  -1.031  -1.211  -1.199  -1.185  -0.927  -0.923  -0.900
286   E        -1.046  -1.044  -1.031  -1.272  -1.262  -1.246  -0.927  -0.923  -0.900
287   T        -1.046  -1.044  -1.031  -0.869  -0.873  -0.843  -0.927  -0.923  -0.900
288   R        -1.046  -1.044  -1.031  -1.043  -1.038  -1.017  -0.927  -0.923  -0.900
289   K         0.119   0.151   0.094  -0.223  -0.164  -0.270  -0.005   0.046  -0.045
290   L         0.119   0.100   0.072  -0.164  -0.198  -0.251  -0.005  -0.036  -0.080
291   C        -1.046  -1.044  -1.031  -0.514  -0.515  -0.487  -0.927  -0.923  -0.900
292   M         0.119   0.151   0.094   0.005   0.050  -0.020  -0.005   0.046  -0.045
293   N         0.119   0.100   0.072   0.189   0.159   0.120  -0.005  -0.036  -0.080
294   L        -1.046  -1.044  -1.031  -1.036  -1.023  -1.010  -0.927  -0.923  -0.900
295   K        -1.046  -1.044  -1.031  -0.877  -0.860  -0.850  -0.927  -0.923  -0.900
296   T        -1.046  -1.044  -1.031  -0.935  -0.938  -0.909  -0.927  -0.923  -0.900
297   N        -1.046  -1.044  -1.031  -1.020  -1.019  -0.994  -0.927  -0.923  -0.900
298   N         0.119   0.100   0.072   0.109   0.074   0.028  -0.005  -0.036  -0.080
299   K         0.119   0.112   0.087  -0.070  -0.082  -0.122  -0.005  -0.016  -0.056
300   K         0.119   0.100   0.072   0.011  -0.017  -0.055  -0.005  -0.036  -0.080
301   R         0.119   0.100   0.072   0.200   0.170   0.132  -0.005  -0.036  -0.080
302   L         1.723   1.725   1.742   1.552   1.556   1.581   1.837   1.840   1.861
303   T         0.119   0.100   0.072   0.224   0.189   0.130  -0.005  -0.036  -0.080
304   E        -1.046  -1.044  -1.031  -1.326  -1.318  -1.300  -0.927  -0.923  -0.900
305   K         0.119   0.100   0.072  -0.181  -0.216  -0.277  -0.005  -0.036  -0.080
306   L         1.723   1.725   1.742   1.552   1.556   1.581   1.837   1.840   1.861
307   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
308   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
309   I        -1.046  -1.044  -1.031  -0.998  -0.999  -0.972  -0.927  -0.923  -0.900
310   Q        -1.046  -1.044  -1.031  -0.994  -0.997  -0.968  -0.927  -0.923  -0.900
311   K         0.119   0.112   0.087  -0.055  -0.066  -0.106  -0.005  -0.016  -0.056
312   D        -1.046  -1.044  -1.031  -1.093  -1.087  -1.067  -0.927  -0.923  -0.900
313   L        -1.046  -1.044  -1.031  -0.939  -0.921  -0.912  -0.927  -0.923  -0.900
314   H         1.723   1.725   1.742   2.042   2.048   2.072   1.837   1.840   1.861
315   P         1.723   1.725   1.742   1.996   2.000   2.026   1.837   1.840   1.861
316   V         0.119   0.100   0.072   0.246   0.210   0.151  -0.005  -0.036  -0.080
317   L         0.119   0.112   0.087   0.061   0.054   0.027  -0.005  -0.016  -0.056
318   N        -1.046  -1.044  -1.031  -1.211  -1.211  -1.185  -0.927  -0.923  -0.900
319   K        -1.046  -1.044  -1.031  -0.920  -0.905  -0.894  -0.927  -0.923  -0.900
320   A         0.119   0.112   0.087   0.310   0.298   0.244  -0.005  -0.016  -0.056
321   M        -1.046  -1.044  -1.031  -0.939  -0.948  -0.912  -0.927  -0.923  -0.900
322   E         0.119   0.151   0.094  -0.105  -0.042  -0.158  -0.005   0.046  -0.045
323   Y        -1.046  -1.044  -1.031  -0.873  -0.882  -0.847  -0.927  -0.923  -0.900
324   T         0.119   0.112   0.087   0.224   0.213   0.160  -0.005  -0.016  -0.056
325   Y        -1.046  -1.044  -1.031  -0.816  -0.816  -0.790  -0.927  -0.923  -0.900
326   G         1.723   1.725   1.742   1.983   1.988   2.014   1.837   1.840   1.861
327   L         1.723   1.725   1.742   1.590   1.594   1.620   1.837   1.840   1.861
328   E        -0.024  -0.023  -0.008  -0.301  -0.300  -0.274  -0.236  -0.234  -0.209
329   S        -0.024  -0.023  -0.008  -0.376  -0.375  -0.349  -0.236  -0.234  -0.209
330   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
331   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
332   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
333   F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
334   M         0.119   0.151   0.094   0.216   0.258   0.186  -0.005   0.046  -0.045
335   H        -1.046  -1.044  -1.031  -0.917  -0.924  -0.890  -0.927  -0.923  -0.900
336   P        -1.046  -1.044  -1.031  -0.812  -0.817  -0.786  -0.927  -0.923  -0.900
337   D        -1.046  -1.044  -1.031  -0.756  -0.745  -0.730  -0.927  -0.923  -0.900
338   G        -1.046  -1.044  -1.031  -0.837  -0.841  -0.811  -0.927  -0.923  -0.900
339   P        -1.046  -1.044  -1.031  -0.976  -0.981  -0.949  -0.927  -0.923  -0.900
340   V        -1.046  -1.044  -1.031  -1.036  -1.043  -1.010  -0.927  -0.923  -0.900
341   T        -1.046  -1.044  -1.031  -0.732  -0.731  -0.705  -0.927  -0.923  -0.900
342   F         0.119   0.151   0.094   0.466   0.517   0.429  -0.005   0.046  -0.045
343   R         0.119   0.100   0.072   0.172   0.141   0.101  -0.005  -0.036  -0.080
344   N        -1.046  -1.044  -1.031  -0.935  -0.930  -0.909  -0.927  -0.923  -0.900
345   D         1.723   1.725   1.742   1.724   1.723   1.754   1.837   1.840   1.861
346   S        -1.046  -1.044  -1.031  -1.066  -1.060  -1.040  -0.927  -0.923  -0.900
347   H         0.119   0.151   0.094   0.275   0.322   0.244  -0.005   0.046  -0.045
348   E         0.119   0.100   0.072  -0.152  -0.182  -0.226  -0.005  -0.036  -0.080
349   L         0.119   0.100   0.072   0.047   0.022  -0.008  -0.005  -0.036  -0.080
350   N         1.723   1.725   1.742   1.754   1.757   1.784   1.837   1.840   1.861
351   L         1.723   1.725   1.742   1.552   1.556   1.581   1.837   1.840   1.861
352   M        -1.046  -1.044  -1.031  -1.108  -1.117  -1.083  -0.927  -0.923  -0.900
353   L        -0.024  -0.023  -0.008  -0.300  -0.298  -0.272  -0.236  -0.234  -0.209
354   N        -0.024  -0.023  -0.008  -0.206  -0.204  -0.179  -0.236  -0.234  -0.209
355   D        -0.024  -0.023  -0.008   0.062   0.065   0.090  -0.236  -0.234  -0.209
356   P        -0.024  -0.023  -0.008   0.136   0.138   0.164  -0.236  -0.234  -0.209
357   I         1.723   1.725   1.742   1.791   1.796   1.821   1.837   1.840   1.861
358   K        -0.024  -0.023  -0.008  -0.038  -0.036  -0.010  -0.236  -0.234  -0.209
359   S        -0.024  -0.023  -0.008  -0.134  -0.132  -0.107  -0.236  -0.234  -0.209
360   T         1.723   1.725   1.742   1.904   1.909   1.935   1.837   1.840   1.861
361   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
362   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
363   V        -0.024  -0.023  -0.008  -0.103  -0.100  -0.075  -0.236  -0.234  -0.209
364   R        -0.024  -0.023  -0.008  -0.252  -0.250  -0.225  -0.236  -0.234  -0.209
365   L        -0.024  -0.023  -0.008  -0.138  -0.136  -0.111  -0.236  -0.234  -0.209
366   D         1.723   1.725   1.742   1.705   1.709   1.735   1.837   1.840   1.861
367   K        -0.024  -0.023  -0.008  -0.103  -0.100  -0.075  -0.236  -0.234  -0.209
368   E        -0.024  -0.023  -0.008  -0.421  -0.419  -0.394  -0.236  -0.234  -0.209
369   E        -0.024  -0.023  -0.008  -0.498  -0.497  -0.471  -0.236  -0.234  -0.209
370   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
371   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
372   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
373   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
374   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
375   P         1.723   1.725   1.742   1.983   1.988   2.014   1.837   1.840   1.861
376   S        -0.024  -0.023  -0.008  -0.345  -0.343  -0.318  -0.236  -0.234  -0.209
377   L        -0.024  -0.023  -0.008  -0.228  -0.226  -0.201  -0.236  -0.234  -0.209
378   K        -0.024  -0.023  -0.008  -0.376  -0.375  -0.349  -0.236  -0.234  -0.209
379   E         1.723   1.725   1.742   1.489   1.493   1.519   1.837   1.840   1.861
380   Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
381   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
382   K         1.723   1.725   1.742   1.548   1.552   1.578   1.837   1.840   1.861
383   K        -0.024  -0.023  -0.008  -0.498  -0.497  -0.471  -0.236  -0.234  -0.209
384   S        -1.046  -1.044  -1.031  -1.136  -1.130  -1.110  -0.927  -0.923  -0.900
385   K        -1.046  -1.044  -1.031  -0.946  -0.933  -0.920  -0.927  -0.923  -0.900
386   E         0.119   0.151   0.094  -0.105  -0.042  -0.158  -0.005   0.046  -0.045
387   L         0.119   0.112   0.087  -0.061  -0.071  -0.109  -0.005  -0.016  -0.056
388   K        -1.046  -1.044  -1.031  -1.132  -1.123  -1.106  -0.927  -0.923  -0.900
389   E        -1.046  -1.044  -1.031  -1.020  -1.001  -0.994  -0.927  -0.923  -0.900
390   T        -1.046  -1.044  -1.031  -0.884  -0.887  -0.858  -0.927  -0.923  -0.900
391   M        -1.046  -1.044  -1.031  -0.718  -0.718  -0.692  -0.927  -0.923  -0.900
392   G        -1.046  -1.044  -1.031  -0.704  -0.706  -0.678  -0.927  -0.923  -0.900
393   Q         0.119   0.100   0.072   0.355   0.326   0.287  -0.005  -0.036  -0.080
394   M         0.119   0.112   0.087   0.286   0.273   0.214  -0.005  -0.016  -0.056
395   I         1.723   1.725   1.742   1.791   1.796   1.821   1.837   1.840   1.861
396   S        -0.024  -0.023  -0.008  -0.206  -0.204  -0.179  -0.236  -0.234  -0.209
397   D         0.119   0.112   0.087  -0.041  -0.057  -0.109  -0.005  -0.016  -0.056
398   S        -1.046  -1.044  -1.031  -0.972  -0.963  -0.946  -0.927  -0.923  -0.900
399   H         0.119   0.151   0.094   0.243   0.289   0.213  -0.005   0.046  -0.045
400   E        -0.024  -0.023  -0.008  -0.295  -0.293  -0.268  -0.236  -0.234  -0.209
401   E         1.723   1.725   1.742   1.489   1.493   1.519   1.837   1.840   1.861
402   E        -1.046  -1.044  -1.031  -1.227  -1.217  -1.201  -0.927  -0.923  -0.900
403   I        -1.046  -1.044  -1.031  -0.998  -0.993  -0.972  -0.927  -0.923  -0.900
404   K        -1.046  -1.044  -1.031  -1.020  -1.010  -0.994  -0.927  -0.923  -0.900
405   E         0.119   0.112   0.087  -0.184  -0.192  -0.238  -0.005  -0.016  -0.056
406   V         0.119   0.100   0.072   0.304   0.270   0.219  -0.005  -0.036  -0.080
407   F         1.723   1.725   1.742   2.013   2.017   2.043   1.837   1.840   1.861
408   V        -1.046  -1.044  -1.031  -0.746  -0.743  -0.719  -0.927  -0.923  -0.900
409   P        -1.046  -1.044  -1.031  -0.994  -1.005  -0.968  -0.927  -0.923  -0.900
410   H        -1.046  -1.044  -1.031  -0.739  -0.741  -0.712  -0.927  -0.923  -0.900
411   H        -1.046  -1.044  -1.031  -0.898  -0.905  -0.872  -0.927  -0.923  -0.900
412   E        -1.046  -1.044  -1.031  -1.013  -0.994  -0.987  -0.927  -0.923  -0.900
413   S         0.119   0.151   0.094  -0.125  -0.070  -0.169  -0.005   0.046  -0.045
414   H         0.119   0.100   0.072   0.286   0.249   0.181  -0.005  -0.036  -0.080
415   Q         1.723   1.725   1.742   1.937   1.941   1.967   1.837   1.840   1.861
416   D        -0.024  -0.023  -0.008  -0.009  -0.007   0.018  -0.236  -0.234  -0.209
417   K         1.723   1.725   1.742   1.577   1.582   1.606   1.837   1.840   1.861
418   T        -1.046  -1.044  -1.031  -1.148  -1.154  -1.122  -0.927  -0.923  -0.900
419   E         0.119   0.100   0.072  -0.137  -0.165  -0.209  -0.005  -0.036  -0.080
420   E        -1.046  -1.044  -1.031  -1.372  -1.360  -1.347  -0.927  -0.923  -0.900
421   D        -1.046  -1.044  -1.031  -0.859  -0.854  -0.832  -0.927  -0.923  -0.900
422   I         1.723   1.725   1.742   1.791   1.796   1.821   1.837   1.840   1.861
423   H        -1.046  -1.044  -1.031  -1.124  -1.134  -1.098  -0.927  -0.923  -0.900
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P53298
Output conservation file - output/P53298
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
