1     M         1.168   1.170   1.183   1.435   1.437   1.454   1.215   1.216   1.231
2     S        -0.414  -0.412  -0.387  -0.435  -0.434  -0.390  -0.603  -0.600  -0.557
3     T        -0.414  -0.412  -0.387  -0.514  -0.513  -0.468  -0.603  -0.600  -0.557
4     I        -0.414  -0.412  -0.387  -0.740  -0.740  -0.690  -0.603  -0.600  -0.557
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     K        -1.339  -1.335  -1.306  -1.391  -1.387  -1.332  -1.209  -1.203  -1.153
7     V        -1.339  -1.335  -1.306  -1.305  -1.304  -1.248  -1.209  -1.203  -1.153
8     I        -0.284  -0.314  -0.343  -0.278  -0.314  -0.340  -0.401  -0.445  -0.488
9     E        -1.339  -1.335  -1.306  -1.254  -1.245  -1.198  -1.209  -1.203  -1.153
10    V        -1.339  -1.335  -1.306  -1.317  -1.314  -1.260  -1.209  -1.203  -1.153
11    Y         1.168   1.170   1.183   1.241   1.243   1.263   1.215   1.216   1.231
12    T        -1.339  -1.335  -1.306  -1.184  -1.172  -1.128  -1.209  -1.203  -1.153
13    Q         1.168   1.170   1.183   1.294   1.296   1.315   1.215   1.216   1.231
14    N        -0.284  -0.276  -0.338  -0.207  -0.192  -0.298  -0.401  -0.387  -0.480
15    G         1.168   1.170   1.183   1.270   1.273   1.291   1.215   1.216   1.231
16    L         1.168   1.170   1.183   0.990   0.992   1.015   1.215   1.216   1.231
17    R         1.168   1.170   1.183   1.208   1.211   1.230   1.215   1.216   1.231
18    K         1.168   1.170   1.183   1.075   1.077   1.099   1.215   1.216   1.231
19    V        -0.284  -0.256  -0.334  -0.398  -0.350  -0.473  -0.401  -0.357  -0.474
20    R        -1.339  -1.335  -1.306  -1.175  -1.167  -1.120  -1.209  -1.203  -1.153
21    P         1.168   1.170   1.183   1.159   1.160   1.182   1.215   1.216   1.231
22    Y         1.168   1.170   1.183   1.241   1.243   1.263   1.215   1.216   1.231
23    Y         1.168   1.170   1.183   1.241   1.243   1.263   1.215   1.216   1.231
24    N        -0.284  -0.276  -0.338  -0.172  -0.159  -0.256  -0.401  -0.387  -0.480
25    R        -1.339  -1.335  -1.306  -1.231  -1.220  -1.174  -1.209  -1.203  -1.153
26    R         1.168   1.170   1.183   1.208   1.211   1.230   1.215   1.216   1.231
27    S        -0.284  -0.276  -0.338  -0.264  -0.247  -0.360  -0.401  -0.387  -0.480
28    A        -0.284  -0.314  -0.343  -0.190  -0.237  -0.291  -0.401  -0.445  -0.488
29    F         1.168   1.170   1.183   1.308   1.310   1.329   1.215   1.216   1.231
30    V         1.168   1.170   1.183   1.183   1.189   1.206   1.215   1.216   1.231
31    K         1.168   1.170   1.183   1.075   1.077   1.099   1.215   1.216   1.231
32    G         1.168   1.170   1.183   1.270   1.273   1.291   1.215   1.216   1.231
33    R         1.168   1.170   1.183   1.208   1.211   1.230   1.215   1.216   1.231
34    W         1.168   1.170   1.183   1.417   1.419   1.436   1.215   1.216   1.231
35    L        -1.339  -1.335  -1.306  -1.246  -1.230  -1.189  -1.209  -1.203  -1.153
36    G        -0.284  -0.276  -0.338  -0.172  -0.158  -0.262  -0.401  -0.387  -0.480
37    K        -0.284  -0.276  -0.338  -0.368  -0.354  -0.448  -0.401  -0.387  -0.480
38    L        -1.339  -1.335  -1.306  -1.394  -1.378  -1.336  -1.209  -1.203  -1.153
39    L        -0.284  -0.276  -0.338  -0.458  -0.443  -0.534  -0.401  -0.387  -0.480
40    I        -1.339  -1.335  -1.306  -1.499  -1.487  -1.439  -1.209  -1.203  -1.153
41    D        -0.284  -0.314  -0.343  -0.238  -0.283  -0.325  -0.401  -0.445  -0.488
42    V        -0.284  -0.314  -0.343  -0.338  -0.388  -0.451  -0.401  -0.445  -0.488
43    L        -0.284  -0.314  -0.343  -0.398  -0.439  -0.468  -0.401  -0.445  -0.488
44    V        -0.284  -0.314  -0.343  -0.338  -0.388  -0.451  -0.401  -0.445  -0.488
45    S        -1.339  -1.335  -1.306  -1.327  -1.320  -1.269  -1.209  -1.203  -1.153
46    E         1.168   1.170   1.183   1.070   1.070   1.094   1.215   1.216   1.231
47    F         1.168   1.170   1.183   1.308   1.310   1.329   1.215   1.216   1.231
48    K        -0.414  -0.412  -0.387  -0.567  -0.565  -0.520  -0.603  -0.600  -0.557
49    L        -0.284  -0.256  -0.334  -0.291  -0.238  -0.397  -0.401  -0.357  -0.474
50    R        -0.284  -0.256  -0.334  -0.168  -0.120  -0.256  -0.401  -0.357  -0.474
51    P        -1.339  -1.335  -1.306  -1.290  -1.283  -1.233  -1.209  -1.203  -1.153
52    R        -1.339  -1.335  -1.306  -1.144  -1.134  -1.089  -1.209  -1.203  -1.153
53    A        -0.284  -0.256  -0.334  -0.345  -0.305  -0.413  -0.401  -0.357  -0.474
54    Y        -0.284  -0.314  -0.343  -0.278  -0.333  -0.393  -0.401  -0.445  -0.488
55    Y        -0.284  -0.314  -0.343  -0.190  -0.236  -0.285  -0.401  -0.445  -0.488
56    L        -1.339  -1.335  -1.306  -1.269  -1.254  -1.212  -1.209  -1.203  -1.153
57    D        -1.339  -1.335  -1.306  -1.330  -1.332  -1.272  -1.209  -1.203  -1.153
58    Q        -0.284  -0.314  -0.343  -0.227  -0.281  -0.346  -0.401  -0.445  -0.488
59    I         1.168   1.170   1.183   1.055   1.059   1.080   1.215   1.216   1.231
60    R        -1.339  -1.335  -1.306  -1.281  -1.273  -1.224  -1.209  -1.203  -1.153
61    K        -1.339  -1.335  -1.306  -1.373  -1.370  -1.314  -1.209  -1.203  -1.153
62    G         1.168   1.170   1.183   1.270   1.273   1.291   1.215   1.216   1.231
63    T        -1.339  -1.335  -1.306  -1.284  -1.270  -1.227  -1.209  -1.203  -1.153
64    Y        -0.284  -0.314  -0.343  -0.284  -0.338  -0.402  -0.401  -0.445  -0.488
65    R        -0.284  -0.256  -0.334  -0.368  -0.323  -0.442  -0.401  -0.357  -0.474
66    L         1.168   1.170   1.183   0.990   0.992   1.015   1.215   1.216   1.231
67    I        -0.284  -0.314  -0.343  -0.488  -0.541  -0.599  -0.401  -0.445  -0.488
68    R         1.168   1.170   1.183   1.208   1.211   1.230   1.215   1.216   1.231
69    D        -0.284  -0.314  -0.343  -0.341  -0.395  -0.451  -0.401  -0.445  -0.488
70    G         1.168   1.170   1.183   1.270   1.273   1.291   1.215   1.216   1.231
71    V        -1.339  -1.335  -1.306  -1.272  -1.269  -1.215  -1.209  -1.203  -1.153
72    P        -1.339  -1.335  -1.306  -1.187  -1.178  -1.131  -1.209  -1.203  -1.153
73    L         1.168   1.170   1.183   0.990   0.992   1.015   1.215   1.216   1.231
74    V        -1.339  -1.335  -1.306  -1.351  -1.349  -1.293  -1.209  -1.203  -1.153
75    P        -1.339  -1.335  -1.306  -1.199  -1.190  -1.143  -1.209  -1.203  -1.153
76    D        -0.414  -0.412  -0.387  -0.635  -0.633  -0.587  -0.603  -0.600  -0.557
77    H        -0.414  -0.412  -0.387  -0.420  -0.418  -0.375  -0.603  -0.600  -0.557
78    L        -0.414  -0.412  -0.387  -0.672  -0.670  -0.624  -0.603  -0.600  -0.557
79    M        -0.414  -0.412  -0.387  -0.445  -0.442  -0.400  -0.603  -0.600  -0.557
80    T        -0.284  -0.256  -0.334  -0.305  -0.257  -0.390  -0.401  -0.357  -0.474
81    T        -0.284  -0.314  -0.343  -0.322  -0.370  -0.422  -0.401  -0.445  -0.488
82    I        -0.284  -0.276  -0.338  -0.409  -0.395  -0.492  -0.401  -0.387  -0.480
83    I         1.168   1.170   1.183   1.055   1.059   1.080   1.215   1.216   1.231
84    K         1.168   1.170   1.183   1.075   1.077   1.099   1.215   1.216   1.231
85    N         1.168   1.170   1.183   1.246   1.248   1.268   1.215   1.216   1.231
86    H        -1.339  -1.335  -1.306  -1.234  -1.236  -1.177  -1.209  -1.203  -1.153
87    D         1.168   1.170   1.183   1.174   1.175   1.196   1.215   1.216   1.231
88    V        -1.339  -1.335  -1.306  -1.423  -1.418  -1.363  -1.209  -1.203  -1.153
89    L         1.168   1.170   1.183   0.990   0.992   1.015   1.215   1.216   1.231
90    E        -0.284  -0.314  -0.343  -0.474  -0.530  -0.586  -0.401  -0.445  -0.488
91    T        -0.284  -0.276  -0.338  -0.296  -0.279  -0.380  -0.401  -0.387  -0.480
92    T        -0.284  -0.314  -0.343  -0.284  -0.329  -0.375  -0.401  -0.445  -0.488
93    T        -1.339  -1.335  -1.306  -1.228  -1.214  -1.171  -1.209  -1.203  -1.153
94    H         1.168   1.170   1.183   1.294   1.297   1.315   1.215   1.216   1.231
95    K        -0.284  -0.314  -0.343  -0.350  -0.394  -0.434  -0.401  -0.445  -0.488
96    H         1.168   1.170   1.183   1.294   1.297   1.315   1.215   1.216   1.231
97    E         1.168   1.170   1.183   1.070   1.070   1.094   1.215   1.216   1.231
98    P         1.168   1.170   1.183   1.159   1.160   1.182   1.215   1.216   1.231
99    P         1.168   1.170   1.183   1.159   1.160   1.182   1.215   1.216   1.231
100   V         1.168   1.170   1.183   1.183   1.189   1.206   1.215   1.216   1.231
101   K        -0.284  -0.276  -0.338  -0.469  -0.454  -0.571  -0.401  -0.387  -0.480
102   Q        -0.284  -0.314  -0.343  -0.151  -0.199  -0.251  -0.401  -0.445  -0.488
103   W         1.168   1.170   1.183   1.417   1.419   1.436   1.215   1.216   1.231
104   C        -0.284  -0.314  -0.343  -0.034  -0.083  -0.141  -0.401  -0.445  -0.488
105   S        -0.284  -0.314  -0.343  -0.300  -0.352  -0.414  -0.401  -0.445  -0.488
106   Q        -1.339  -1.335  -1.306  -1.184  -1.184  -1.128  -1.209  -1.203  -1.153
107   E        -0.284  -0.314  -0.343  -0.444  -0.497  -0.549  -0.401  -0.445  -0.488
108   V        -1.339  -1.335  -1.306  -1.087  -1.071  -1.033  -1.209  -1.203  -1.153
109   E        -0.414  -0.412  -0.387  -0.622  -0.622  -0.575  -0.603  -0.600  -0.557
110   A        -0.414  -0.412  -0.387  -0.525  -0.519  -0.478  -0.603  -0.600  -0.557
111   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
112   D        -0.414  -0.412  -0.387  -0.445  -0.442  -0.400  -0.603  -0.600  -0.557
113   L        -0.414  -0.412  -0.387  -0.753  -0.751  -0.703  -0.603  -0.600  -0.557
114   P         1.168   1.170   1.183   1.182   1.184   1.204   1.215   1.216   1.231
115   G         1.168   1.170   1.183   1.272   1.274   1.293   1.215   1.216   1.231
116   -         1.168   1.170   1.183   1.070   1.078   1.094   1.215   1.216   1.231
117   R        -1.339  -1.335  -1.306  -1.257  -1.246  -1.201  -1.209  -1.203  -1.153
118   I         1.168   1.170   1.183   1.055   1.059   1.080   1.215   1.216   1.231
119   A        -0.284  -0.314  -0.343  -0.091  -0.131  -0.170  -0.401  -0.445  -0.488
120   G         1.168   1.170   1.183   1.270   1.273   1.291   1.215   1.216   1.231
121   F        -0.284  -0.256  -0.334  -0.338  -0.296  -0.402  -0.401  -0.357  -0.474
122   N        -1.339  -1.335  -1.306  -1.257  -1.256  -1.201  -1.209  -1.203  -1.153
123   I         1.168   1.170   1.183   1.055   1.059   1.080   1.215   1.216   1.231
124   V         1.168   1.170   1.183   1.183   1.189   1.206   1.215   1.216   1.231
125   F        -1.339  -1.335  -1.306  -1.098  -1.093  -1.044  -1.209  -1.203  -1.153
126   E        -0.284  -0.314  -0.343  -0.331  -0.376  -0.410  -0.401  -0.445  -0.488
127   D         1.168   1.170   1.183   1.174   1.175   1.196   1.215   1.216   1.231
128   E         1.168   1.170   1.183   1.070   1.070   1.094   1.215   1.216   1.231
129   S        -1.339  -1.335  -1.306  -1.150  -1.140  -1.094  -1.209  -1.203  -1.153
130   I        -0.284  -0.256  -0.334  -0.519  -0.471  -0.602  -0.401  -0.357  -0.474
131   L         1.168   1.170   1.183   0.990   0.992   1.015   1.215   1.216   1.231
132   V         1.168   1.170   1.183   1.183   1.189   1.206   1.215   1.216   1.231
133   I         1.168   1.170   1.183   1.055   1.059   1.080   1.215   1.216   1.231
134   D        -0.284  -0.256  -0.334  -0.227  -0.180  -0.315  -0.401  -0.357  -0.474
135   K         1.168   1.170   1.183   1.075   1.077   1.099   1.215   1.216   1.231
136   P         1.168   1.170   1.183   1.159   1.160   1.182   1.215   1.216   1.231
137   S        -1.339  -1.335  -1.306  -1.079  -1.072  -1.024  -1.209  -1.203  -1.153
138   G         1.168   1.170   1.183   1.270   1.273   1.291   1.215   1.216   1.231
139   I         1.168   1.170   1.183   1.055   1.059   1.080   1.215   1.216   1.231
140   P         1.168   1.170   1.183   1.159   1.160   1.182   1.215   1.216   1.231
141   V        -0.284  -0.276  -0.338  -0.338  -0.320  -0.441  -0.401  -0.387  -0.480
142   H         1.168   1.170   1.183   1.294   1.297   1.315   1.215   1.216   1.231
143   P         1.168   1.170   1.183   1.159   1.160   1.182   1.215   1.216   1.231
144   T         1.168   1.170   1.183   1.149   1.153   1.172   1.215   1.216   1.231
145   G        -0.284  -0.314  -0.343  -0.164  -0.210  -0.261  -0.401  -0.445  -0.488
146   Q        -1.339  -1.335  -1.306  -1.287  -1.281  -1.230  -1.209  -1.203  -1.153
147   F        -0.284  -0.276  -0.338  -0.140  -0.126  -0.233  -0.401  -0.387  -0.480
148   Y         1.168   1.170   1.183   1.241   1.243   1.263   1.215   1.216   1.231
149   Q        -1.339  -1.335  -1.306  -1.219  -1.221  -1.163  -1.209  -1.203  -1.153
150   N         1.168   1.170   1.183   1.246   1.248   1.268   1.215   1.216   1.231
151   T         1.168   1.170   1.183   1.149   1.153   1.172   1.215   1.216   1.231
152   I        -0.284  -0.256  -0.334  -0.519  -0.471  -0.602  -0.401  -0.357  -0.474
153   T         1.168   1.170   1.183   1.149   1.153   1.172   1.215   1.216   1.231
154   E         1.168   1.170   1.183   1.070   1.070   1.094   1.215   1.216   1.231
155   L        -0.284  -0.276  -0.338  -0.519  -0.504  -0.608  -0.401  -0.387  -0.480
156   L         1.168   1.170   1.183   0.990   0.992   1.015   1.215   1.216   1.231
157   K         1.168   1.170   1.183   1.075   1.077   1.099   1.215   1.216   1.231
158   L        -1.339  -1.335  -1.306  -1.401  -1.387  -1.342  -1.209  -1.203  -1.153
159   H        -1.339  -1.335  -1.306  -1.150  -1.145  -1.094  -1.209  -1.203  -1.153
160   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
161   G         1.168   1.170   1.183   1.270   1.273   1.291   1.215   1.216   1.231
162   V        -0.284  -0.314  -0.343  -0.253  -0.297  -0.346  -0.401  -0.445  -0.488
163   D        -1.339  -1.335  -1.306  -1.228  -1.224  -1.171  -1.209  -1.203  -1.153
164   A        -0.284  -0.314  -0.343  -0.205  -0.252  -0.310  -0.401  -0.445  -0.488
165   L        -0.284  -0.314  -0.343  -0.404  -0.446  -0.477  -0.401  -0.445  -0.488
166   P         1.168   1.170   1.183   1.159   1.160   1.182   1.215   1.216   1.231
167   C        -0.284  -0.276  -0.338  -0.036  -0.021  -0.134  -0.401  -0.387  -0.480
168   Y         1.168   1.170   1.183   1.241   1.243   1.263   1.215   1.216   1.231
169   R         1.168   1.170   1.183   1.208   1.211   1.230   1.215   1.216   1.231
170   L         1.168   1.170   1.183   0.990   0.992   1.015   1.215   1.216   1.231
171   D         1.168   1.170   1.183   1.174   1.175   1.196   1.215   1.216   1.231
172   K         1.168   1.170   1.183   1.075   1.077   1.099   1.215   1.216   1.231
173   I        -0.284  -0.276  -0.338  -0.398  -0.381  -0.479  -0.401  -0.387  -0.480
174   T         1.168   1.170   1.183   1.149   1.153   1.172   1.215   1.216   1.231
175   S         1.168   1.170   1.183   1.217   1.222   1.239   1.215   1.216   1.231
176   G         1.168   1.170   1.183   1.270   1.273   1.291   1.215   1.216   1.231
177   L         1.168   1.170   1.183   0.990   0.992   1.015   1.215   1.216   1.231
178   L         1.168   1.170   1.183   0.990   0.992   1.015   1.215   1.216   1.231
179   I         1.168   1.170   1.183   1.055   1.059   1.080   1.215   1.216   1.231
180   L         1.168   1.170   1.183   0.990   0.992   1.015   1.215   1.216   1.231
181   A        -0.284  -0.276  -0.338  -0.190  -0.174  -0.282  -0.401  -0.387  -0.480
182   K         1.168   1.170   1.183   1.075   1.077   1.099   1.215   1.216   1.231
183   N        -0.284  -0.276  -0.338  -0.227  -0.213  -0.322  -0.401  -0.387  -0.480
184   S        -1.339  -1.335  -1.306  -1.290  -1.284  -1.233  -1.209  -1.203  -1.153
185   Q        -1.339  -1.335  -1.306  -1.231  -1.232  -1.174  -1.209  -1.203  -1.153
186   S        -1.339  -1.335  -1.306  -1.281  -1.274  -1.224  -1.209  -1.203  -1.153
187   A         1.168   1.170   1.183   1.265   1.268   1.287   1.215   1.216   1.231
188   G        -1.339  -1.335  -1.306  -1.164  -1.157  -1.108  -1.209  -1.203  -1.153
189   E        -1.339  -1.335  -1.306  -1.173  -1.165  -1.117  -1.209  -1.203  -1.153
190   I        -0.284  -0.256  -0.334  -0.338  -0.285  -0.433  -0.401  -0.357  -0.474
191   Q         1.168   1.170   1.183   1.294   1.296   1.315   1.215   1.216   1.231
192   K        -0.284  -0.314  -0.343  -0.363  -0.408  -0.451  -0.401  -0.445  -0.488
193   S        -0.284  -0.256  -0.334  -0.363  -0.318  -0.436  -0.401  -0.357  -0.474
194   I         1.168   1.170   1.183   1.055   1.059   1.080   1.215   1.216   1.231
195   R         1.168   1.170   1.183   1.208   1.211   1.230   1.215   1.216   1.231
196   S        -0.284  -0.314  -0.343  -0.253  -0.301  -0.356  -0.401  -0.445  -0.488
197   R        -0.284  -0.276  -0.338  -0.207  -0.192  -0.288  -0.401  -0.387  -0.480
198   D        -0.284  -0.276  -0.338  -0.341  -0.327  -0.441  -0.401  -0.387  -0.480
199   M         1.168   1.170   1.183   1.435   1.437   1.454   1.215   1.216   1.231
200   I        -1.339  -1.335  -1.306  -1.351  -1.345  -1.293  -1.209  -1.203  -1.153
201   K         1.168   1.170   1.183   1.075   1.077   1.099   1.215   1.216   1.231
202   I        -1.339  -1.335  -1.306  -1.173  -1.162  -1.117  -1.209  -1.203  -1.153
203   Y         1.168   1.170   1.183   1.241   1.243   1.263   1.215   1.216   1.231
204   L         1.168   1.170   1.183   0.990   0.992   1.015   1.215   1.216   1.231
205   A         1.168   1.170   1.183   1.265   1.268   1.287   1.215   1.216   1.231
206   R         1.168   1.170   1.183   1.208   1.211   1.230   1.215   1.216   1.231
207   V         1.168   1.170   1.183   1.183   1.189   1.206   1.215   1.216   1.231
208   K        -0.284  -0.276  -0.338  -0.432  -0.419  -0.526  -0.401  -0.387  -0.480
209   G         1.168   1.170   1.183   1.270   1.273   1.291   1.215   1.216   1.231
210   R        -1.339  -1.335  -1.306  -1.275  -1.274  -1.218  -1.209  -1.203  -1.153
211   F         1.168   1.170   1.183   1.308   1.310   1.329   1.215   1.216   1.231
212   P         1.168   1.170   1.183   1.159   1.160   1.182   1.215   1.216   1.231
213   H        -0.284  -0.314  -0.343  -0.229  -0.284  -0.348  -0.401  -0.445  -0.488
214   S        -1.339  -1.335  -1.306  -1.275  -1.267  -1.218  -1.209  -1.203  -1.153
215   E        -0.414  -0.412  -0.387  -0.511  -0.508  -0.464  -0.603  -0.600  -0.557
216   L        -0.414  -0.412  -0.387  -0.704  -0.702  -0.655  -0.603  -0.600  -0.557
217   I        -0.414  -0.412  -0.387  -0.635  -0.633  -0.587  -0.603  -0.600  -0.557
218   L        -0.414  -0.412  -0.387  -0.646  -0.643  -0.598  -0.603  -0.600  -0.557
219   D        -0.414  -0.412  -0.387  -0.415  -0.413  -0.370  -0.603  -0.600  -0.557
220   N        -0.414  -0.412  -0.387  -0.557  -0.554  -0.510  -0.603  -0.600  -0.557
221   E         1.168   1.170   1.183   1.105   1.107   1.128   1.215   1.216   1.231
222   N        -0.414  -0.412  -0.387  -0.485  -0.483  -0.439  -0.603  -0.600  -0.557
223   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
224   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
225   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
226   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
227   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
228   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
229   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
230   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
231   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
232   A        -0.414  -0.412  -0.387  -0.557  -0.554  -0.510  -0.603  -0.600  -0.557
233   A        -0.414  -0.412  -0.387  -0.511  -0.508  -0.464  -0.603  -0.600  -0.557
234   E         1.168   1.170   1.183   1.105   1.107   1.128   1.215   1.216   1.231
235   T        -0.414  -0.412  -0.387  -0.455  -0.452  -0.410  -0.603  -0.600  -0.557
236   T        -0.414  -0.412  -0.387  -0.640  -0.638  -0.592  -0.603  -0.600  -0.557
237   F        -0.414  -0.412  -0.387  -0.506  -0.503  -0.459  -0.603  -0.600  -0.557
238   E        -0.414  -0.412  -0.387  -0.480  -0.478  -0.434  -0.603  -0.600  -0.557
239   D         1.168   1.170   1.183   1.196   1.198   1.218   1.215   1.216   1.231
240   T        -0.414  -0.412  -0.387  -0.485  -0.483  -0.439  -0.603  -0.600  -0.557
241   S         1.168   1.170   1.183   1.189   1.191   1.211   1.215   1.216   1.231
242   K        -0.414  -0.412  -0.387  -0.688  -0.686  -0.640  -0.603  -0.600  -0.557
243   V        -0.414  -0.412  -0.387  -0.672  -0.670  -0.624  -0.603  -0.600  -0.557
244   T        -0.284  -0.314  -0.343  -0.273  -0.316  -0.361  -0.401  -0.445  -0.488
245   V        -0.284  -0.276  -0.338  -0.338  -0.320  -0.441  -0.401  -0.387  -0.480
246   E        -0.284  -0.314  -0.343  -0.388  -0.438  -0.480  -0.401  -0.445  -0.488
247   M        -1.339  -1.335  -1.306  -1.190  -1.196  -1.134  -1.209  -1.203  -1.153
248   T        -0.284  -0.256  -0.334  -0.264  -0.214  -0.353  -0.401  -0.357  -0.474
249   P        -0.284  -0.276  -0.338  -0.307  -0.294  -0.396  -0.401  -0.387  -0.480
250   I        -0.284  -0.276  -0.338  -0.398  -0.381  -0.479  -0.401  -0.387  -0.480
251   Y         1.168   1.170   1.183   1.241   1.243   1.263   1.215   1.216   1.231
252   S        -0.284  -0.256  -0.334  -0.296  -0.248  -0.374  -0.401  -0.357  -0.474
253   I        -1.339  -1.335  -1.306  -1.210  -1.189  -1.154  -1.209  -1.203  -1.153
254   D        -0.284  -0.276  -0.338  -0.341  -0.327  -0.441  -0.401  -0.387  -0.480
255   P        -0.284  -0.314  -0.343  -0.391  -0.447  -0.509  -0.401  -0.445  -0.488
256   K         1.168   1.170   1.183   1.075   1.077   1.099   1.215   1.216   1.231
257   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
258   R        -0.284  -0.256  -0.334  -0.368  -0.323  -0.442  -0.401  -0.357  -0.474
259   Q        -0.284  -0.314  -0.343  -0.164  -0.212  -0.267  -0.401  -0.445  -0.488
260   F        -1.339  -1.335  -1.306  -1.231  -1.235  -1.174  -1.209  -1.203  -1.153
261   P         1.168   1.170   1.183   1.159   1.160   1.182   1.215   1.216   1.231
262   V        -0.414  -0.412  -0.387  -0.526  -0.523  -0.480  -0.603  -0.600  -0.557
263   G         1.168   1.170   1.183   1.272   1.274   1.293   1.215   1.216   1.231
264   L         1.168   1.170   1.183   0.990   0.992   1.015   1.215   1.216   1.231
265   S         1.168   1.170   1.183   1.217   1.222   1.239   1.215   1.216   1.231
266   T        -1.339  -1.335  -1.306  -1.311  -1.303  -1.254  -1.209  -1.203  -1.153
267   S        -1.339  -1.335  -1.306  -1.388  -1.390  -1.329  -1.209  -1.203  -1.153
268   K        -0.284  -0.276  -0.338  -0.368  -0.354  -0.448  -0.401  -0.387  -0.480
269   D        -0.284  -0.276  -0.338  -0.273  -0.259  -0.359  -0.401  -0.387  -0.480
270   A         1.168   1.170   1.183   1.265   1.268   1.287   1.215   1.216   1.231
271   I        -1.339  -1.335  -1.306  -1.351  -1.335  -1.293  -1.209  -1.203  -1.153
272   T         1.168   1.170   1.183   1.149   1.153   1.172   1.215   1.216   1.231
273   K        -1.339  -1.335  -1.306  -1.496  -1.491  -1.436  -1.209  -1.203  -1.153
274   F         1.168   1.170   1.183   1.308   1.310   1.329   1.215   1.216   1.231
275   Y        -0.284  -0.314  -0.343  -0.278  -0.333  -0.393  -0.401  -0.445  -0.488
276   P        -0.284  -0.314  -0.343  -0.391  -0.447  -0.509  -0.401  -0.445  -0.488
277   I        -0.284  -0.314  -0.343  -0.278  -0.314  -0.340  -0.401  -0.445  -0.488
278   R        -1.339  -1.335  -1.306  -1.397  -1.397  -1.339  -1.209  -1.203  -1.153
279   Y         1.168   1.170   1.183   1.241   1.243   1.263   1.215   1.216   1.231
280   F        -0.284  -0.314  -0.343  -0.170  -0.221  -0.280  -0.401  -0.445  -0.488
281   S        -1.339  -1.335  -1.306  -1.219  -1.210  -1.163  -1.209  -1.203  -1.153
282   H        -0.284  -0.314  -0.343  -0.179  -0.227  -0.286  -0.401  -0.445  -0.488
283   A        -1.339  -1.335  -1.306  -1.311  -1.307  -1.254  -1.209  -1.203  -1.153
284   D        -0.284  -0.276  -0.338  -0.260  -0.247  -0.343  -0.401  -0.387  -0.480
285   E        -0.284  -0.314  -0.343  -0.331  -0.376  -0.410  -0.401  -0.445  -0.488
286   T        -0.284  -0.256  -0.334  -0.264  -0.214  -0.353  -0.401  -0.357  -0.474
287   V        -0.284  -0.256  -0.334  -0.398  -0.350  -0.473  -0.401  -0.357  -0.474
288   V         1.168   1.170   1.183   1.183   1.189   1.206   1.215   1.216   1.231
289   A        -0.284  -0.314  -0.343  -0.291  -0.347  -0.417  -0.401  -0.445  -0.488
290   C         1.168   1.170   1.183   1.412   1.414   1.431   1.215   1.216   1.231
291   K        -0.284  -0.276  -0.338  -0.368  -0.354  -0.448  -0.401  -0.387  -0.480
292   P         1.168   1.170   1.183   1.159   1.160   1.182   1.215   1.216   1.231
293   I        -0.284  -0.314  -0.343  -0.338  -0.379  -0.414  -0.401  -0.445  -0.488
294   T         1.168   1.170   1.183   1.149   1.153   1.172   1.215   1.216   1.231
295   G         1.168   1.170   1.183   1.270   1.273   1.291   1.215   1.216   1.231
296   R         1.168   1.170   1.183   1.208   1.211   1.230   1.215   1.216   1.231
297   T         1.168   1.170   1.183   1.149   1.153   1.172   1.215   1.216   1.231
298   H         1.168   1.170   1.183   1.294   1.297   1.315   1.215   1.216   1.231
299   Q         1.168   1.170   1.183   1.294   1.296   1.315   1.215   1.216   1.231
300   I         1.168   1.170   1.183   1.055   1.059   1.080   1.215   1.216   1.231
301   R         1.168   1.170   1.183   1.208   1.211   1.230   1.215   1.216   1.231
302   I         1.168   1.170   1.183   1.055   1.059   1.080   1.215   1.216   1.231
303   H         1.168   1.170   1.183   1.294   1.297   1.315   1.215   1.216   1.231
304   L         1.168   1.170   1.183   0.990   0.992   1.015   1.215   1.216   1.231
305   A         1.168   1.170   1.183   1.265   1.268   1.287   1.215   1.216   1.231
306   R         1.168   1.170   1.183   1.208   1.211   1.230   1.215   1.216   1.231
307   L        -0.284  -0.314  -0.343  -0.404  -0.446  -0.477  -0.401  -0.445  -0.488
308   G        -0.284  -0.276  -0.338  -0.172  -0.158  -0.262  -0.401  -0.387  -0.480
309   H         1.168   1.170   1.183   1.294   1.297   1.315   1.215   1.216   1.231
310   P         1.168   1.170   1.183   1.159   1.160   1.182   1.215   1.216   1.231
311   I         1.168   1.170   1.183   1.055   1.059   1.080   1.215   1.216   1.231
312   V        -0.284  -0.314  -0.343  -0.296  -0.341  -0.398  -0.401  -0.445  -0.488
313   N         1.168   1.170   1.183   1.246   1.248   1.268   1.215   1.216   1.231
314   D         1.168   1.170   1.183   1.174   1.175   1.196   1.215   1.216   1.231
315   S        -1.339  -1.335  -1.306  -1.290  -1.284  -1.233  -1.209  -1.203  -1.153
316   V        -1.339  -1.335  -1.306  -1.275  -1.261  -1.218  -1.209  -1.203  -1.153
317   Y         1.168   1.170   1.183   1.241   1.243   1.263   1.215   1.216   1.231
318   C        -1.339  -1.335  -1.306  -1.079  -1.076  -1.024  -1.209  -1.203  -1.153
319   S        -1.339  -1.335  -1.306  -1.302  -1.304  -1.245  -1.209  -1.203  -1.153
320   H        -1.339  -1.335  -1.306  -1.278  -1.275  -1.221  -1.209  -1.203  -1.153
321   I        -0.284  -0.314  -0.343  -0.368  -0.411  -0.450  -0.401  -0.445  -0.488
322   T        -0.284  -0.314  -0.343  -0.296  -0.340  -0.389  -0.401  -0.445  -0.488
323   K        -1.339  -1.335  -1.306  -1.348  -1.338  -1.290  -1.209  -1.203  -1.153
324   Y         1.168   1.170   1.183   1.241   1.243   1.263   1.215   1.216   1.231
325   P         1.168   1.170   1.183   1.159   1.160   1.182   1.215   1.216   1.231
326   E        -0.284  -0.314  -0.343  -0.474  -0.530  -0.586  -0.401  -0.445  -0.488
327   R         1.168   1.170   1.183   1.208   1.211   1.230   1.215   1.216   1.231
328   L        -0.284  -0.314  -0.343  -0.441  -0.485  -0.522  -0.401  -0.445  -0.488
329   K        -1.339  -1.335  -1.306  -1.287  -1.277  -1.230  -1.209  -1.203  -1.153
330   F         1.168   1.170   1.183   1.308   1.310   1.329   1.215   1.216   1.231
331   I         1.168   1.170   1.183   1.055   1.059   1.080   1.215   1.216   1.231
332   T        -1.339  -1.335  -1.306  -1.360  -1.356  -1.302  -1.209  -1.203  -1.153
333   Q        -1.339  -1.335  -1.306  -1.254  -1.256  -1.198  -1.209  -1.203  -1.153
334   F        -1.339  -1.335  -1.306  -1.296  -1.292  -1.239  -1.209  -1.203  -1.153
335   P        -0.284  -0.276  -0.338  -0.264  -0.252  -0.345  -0.401  -0.387  -0.480
336   R        -1.339  -1.335  -1.306  -1.228  -1.223  -1.171  -1.209  -1.203  -1.153
337   W         1.168   1.170   1.183   1.417   1.419   1.436   1.215   1.216   1.231
338   E        -1.339  -1.335  -1.306  -1.345  -1.336  -1.287  -1.209  -1.203  -1.153
339   N        -1.339  -1.335  -1.306  -1.237  -1.229  -1.180  -1.209  -1.203  -1.153
340   Q        -0.414  -0.412  -0.387  -0.579  -0.573  -0.532  -0.603  -0.600  -0.557
341   Q        -1.339  -1.335  -1.306  -1.178  -1.176  -1.123  -1.209  -1.203  -1.153
342   D        -1.339  -1.335  -1.306  -1.308  -1.299  -1.251  -1.209  -1.203  -1.153
343   L        -0.284  -0.314  -0.343  -0.512  -0.563  -0.609  -0.401  -0.445  -0.488
344   D        -1.339  -1.335  -1.306  -1.287  -1.278  -1.230  -1.209  -1.203  -1.153
345   A        -1.339  -1.335  -1.306  -1.308  -1.309  -1.251  -1.209  -1.203  -1.153
346   E         1.168   1.170   1.183   1.070   1.070   1.094   1.215   1.216   1.231
347   E        -0.284  -0.314  -0.343  -0.434  -0.487  -0.537  -0.401  -0.445  -0.488
348   L         1.168   1.170   1.183   0.990   0.992   1.015   1.215   1.216   1.231
349   K        -1.339  -1.335  -1.306  -1.305  -1.293  -1.248  -1.209  -1.203  -1.153
350   V        -1.339  -1.335  -1.306  -1.413  -1.410  -1.354  -1.209  -1.203  -1.153
351   R        -0.284  -0.276  -0.338  -0.273  -0.257  -0.368  -0.401  -0.387  -0.480
352   F         1.168   1.170   1.183   1.308   1.310   1.329   1.215   1.216   1.231
353   Q        -0.284  -0.314  -0.343  -0.229  -0.284  -0.348  -0.401  -0.445  -0.488
354   K        -1.339  -1.335  -1.306  -1.423  -1.409  -1.363  -1.209  -1.203  -1.153
355   F        -0.284  -0.314  -0.343  -0.216  -0.272  -0.336  -0.401  -0.445  -0.488
356   V        -1.339  -1.335  -1.306  -1.477  -1.474  -1.417  -1.209  -1.203  -1.153
357   D        -0.284  -0.276  -0.338  -0.238  -0.225  -0.316  -0.401  -0.387  -0.480
358   E        -0.284  -0.314  -0.343  -0.388  -0.438  -0.480  -0.401  -0.445  -0.488
359   T        -1.339  -1.335  -1.306  -1.275  -1.264  -1.218  -1.209  -1.203  -1.153
360   K        -1.339  -1.335  -1.306  -1.263  -1.246  -1.206  -1.209  -1.203  -1.153
361   N        -1.339  -1.335  -1.306  -1.175  -1.173  -1.120  -1.209  -1.203  -1.153
362   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
363   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
364   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
365   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
366   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
367   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
368   N        -1.339  -1.335  -1.306  -1.121  -1.113  -1.066  -1.209  -1.203  -1.153
369   C        -1.339  -1.335  -1.306  -1.317  -1.326  -1.260  -1.209  -1.203  -1.153
370   R        -0.284  -0.256  -0.334  -0.211  -0.165  -0.297  -0.401  -0.357  -0.474
371   T        -1.339  -1.335  -1.306  -1.435  -1.432  -1.376  -1.209  -1.203  -1.153
372   M        -0.284  -0.256  -0.334  -0.108  -0.068  -0.173  -0.401  -0.357  -0.474
373   E        -1.339  -1.335  -1.306  -1.135  -1.125  -1.080  -1.209  -1.203  -1.153
374   T        -1.339  -1.335  -1.306  -1.382  -1.380  -1.323  -1.209  -1.203  -1.153
375   F        -1.339  -1.335  -1.306  -1.184  -1.178  -1.128  -1.209  -1.203  -1.153
376   C         1.168   1.170   1.183   1.412   1.414   1.431   1.215   1.216   1.231
377   P        -0.284  -0.276  -0.338  -0.287  -0.273  -0.371  -0.401  -0.387  -0.480
378   E         1.168   1.170   1.183   1.070   1.070   1.094   1.215   1.216   1.231
379   C         1.168   1.170   1.183   1.412   1.414   1.431   1.215   1.216   1.231
380   H        -1.339  -1.335  -1.306  -1.161  -1.159  -1.106  -1.209  -1.203  -1.153
381   T        -1.339  -1.335  -1.306  -1.314  -1.312  -1.257  -1.209  -1.203  -1.153
382   V        -1.339  -1.335  -1.306  -1.467  -1.464  -1.407  -1.209  -1.203  -1.153
383   D        -1.339  -1.335  -1.306  -1.147  -1.130  -1.091  -1.209  -1.203  -1.153
384   L        -0.284  -0.314  -0.343  -0.469  -0.517  -0.557  -0.401  -0.445  -0.488
385   K        -0.284  -0.276  -0.338  -0.363  -0.349  -0.442  -0.401  -0.387  -0.480
386   D         1.168   1.170   1.183   1.174   1.175   1.196   1.215   1.216   1.231
387   P         1.168   1.170   1.183   1.159   1.160   1.182   1.215   1.216   1.231
388   V        -1.339  -1.335  -1.306  -1.302  -1.295  -1.245  -1.209  -1.203  -1.153
389   L        -0.284  -0.256  -0.334  -0.391  -0.341  -0.490  -0.401  -0.357  -0.474
390   S        -0.284  -0.256  -0.334  -0.368  -0.325  -0.441  -0.401  -0.357  -0.474
391   D        -0.284  -0.314  -0.343  -0.273  -0.320  -0.368  -0.401  -0.445  -0.488
392   L         1.168   1.170   1.183   0.990   0.992   1.015   1.215   1.216   1.231
393   E        -0.284  -0.276  -0.338  -0.368  -0.356  -0.446  -0.401  -0.387  -0.480
394   L        -0.284  -0.276  -0.338  -0.519  -0.504  -0.608  -0.401  -0.387  -0.480
395   W        -1.339  -1.335  -1.306  -1.104  -1.103  -1.049  -1.209  -1.203  -1.153
396   L         1.168   1.170   1.183   0.990   0.992   1.015   1.215   1.216   1.231
397   H         1.168   1.170   1.183   1.294   1.297   1.315   1.215   1.216   1.231
398   A         1.168   1.170   1.183   1.265   1.268   1.287   1.215   1.216   1.231
399   W         1.168   1.170   1.183   1.417   1.419   1.436   1.215   1.216   1.231
400   K        -0.284  -0.256  -0.334  -0.307  -0.256  -0.402  -0.401  -0.357  -0.474
401   Y         1.168   1.170   1.183   1.241   1.243   1.263   1.215   1.216   1.231
402   E        -1.339  -1.335  -1.306  -1.391  -1.386  -1.332  -1.209  -1.203  -1.153
403   E        -1.339  -1.335  -1.306  -1.296  -1.285  -1.239  -1.209  -1.203  -1.153
404   I        -1.339  -1.335  -1.306  -1.423  -1.420  -1.363  -1.209  -1.203  -1.153
405   N        -1.339  -1.335  -1.306  -1.311  -1.309  -1.254  -1.209  -1.203  -1.153
406   G        -0.414  -0.412  -0.387  -0.516  -0.513  -0.469  -0.603  -0.600  -0.557
407   K        -0.414  -0.412  -0.387  -0.614  -0.611  -0.566  -0.603  -0.600  -0.557
408   F        -0.284  -0.256  -0.334  -0.398  -0.358  -0.456  -0.401  -0.357  -0.474
409   K        -1.339  -1.335  -1.306  -1.373  -1.370  -1.314  -1.209  -1.203  -1.153
410   F         1.168   1.170   1.183   1.308   1.310   1.329   1.215   1.216   1.231
411   K        -0.284  -0.314  -0.343  -0.432  -0.484  -0.536  -0.401  -0.445  -0.488
412   T         1.168   1.170   1.183   1.149   1.153   1.172   1.215   1.216   1.231
413   D        -0.284  -0.276  -0.338  -0.341  -0.327  -0.441  -0.401  -0.387  -0.480
414   L        -0.284  -0.314  -0.343  -0.430  -0.474  -0.508  -0.401  -0.445  -0.488
415   P         1.168   1.170   1.183   1.159   1.160   1.182   1.215   1.216   1.231
416   K        -1.339  -1.335  -1.306  -1.237  -1.227  -1.180  -1.209  -1.203  -1.153
417   W         1.168   1.170   1.183   1.417   1.419   1.436   1.215   1.216   1.231
418   A        -0.284  -0.276  -0.338  -0.205  -0.188  -0.300  -0.401  -0.387  -0.480
419   Q        -1.339  -1.335  -1.306  -1.272  -1.272  -1.215  -1.209  -1.203  -1.153
420   L        -0.414  -0.412  -0.387  -0.590  -0.589  -0.542  -0.603  -0.600  -0.557
421   D        -0.414  -0.412  -0.387  -0.622  -0.622  -0.575  -0.603  -0.600  -0.557
422   N         1.168   1.170   1.183   1.246   1.248   1.268   1.215   1.216   1.231
423   S        -0.284  -0.256  -0.334  -0.368  -0.325  -0.441  -0.401  -0.357  -0.474
424   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
425   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
426   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P53294
Output conservation file - output/P53294
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
