1     M         1.858   1.858   1.858   2.203   2.203   2.203   1.858   1.858   1.858
2     K        -0.537  -0.537  -0.537  -0.540  -0.540  -0.540  -0.537  -0.537  -0.537
3     H        -0.537  -0.537  -0.537  -0.688  -0.688  -0.688  -0.537  -0.537  -0.537
4     N         1.858   1.858   1.858   1.958   1.958   1.958   1.858   1.858   1.858
5     R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    A        -0.537  -0.537  -0.537  -0.389  -0.389  -0.389  -0.537  -0.537  -0.537
13    V        -0.537  -0.537  -0.537  -0.389  -0.389  -0.389  -0.537  -0.537  -0.537
14    S        -0.537  -0.537  -0.537  -0.428  -0.428  -0.428  -0.537  -0.537  -0.537
15    G        -0.537  -0.537  -0.537  -0.303  -0.303  -0.303  -0.537  -0.537  -0.537
16    F        -0.537  -0.537  -0.537  -0.919  -0.919  -0.919  -0.537  -0.537  -0.537
17    K        -0.537  -0.537  -0.537  -0.500  -0.500  -0.500  -0.537  -0.537  -0.537
18    Q        -0.537  -0.537  -0.537  -0.280  -0.280  -0.280  -0.537  -0.537  -0.537
19    I        -0.537  -0.537  -0.537  -0.638  -0.638  -0.638  -0.537  -0.537  -0.537
20    I         1.858   1.858   1.858   1.649   1.649   1.649   1.858   1.858   1.858
21    R         1.858   1.858   1.858   1.904   1.904   1.904   1.858   1.858   1.858
22    R        -0.537  -0.537  -0.537  -0.452  -0.452  -0.452  -0.537  -0.537  -0.537
23    L         1.858   1.858   1.858   1.268   1.268   1.268   1.858   1.858   1.858
24    L        -0.537  -0.537  -0.537  -0.755  -0.755  -0.755  -0.537  -0.537  -0.537
25    L        -0.537  -0.537  -0.537  -0.730  -0.730  -0.730  -0.537  -0.537  -0.537
26    L        -0.537  -0.537  -0.537  -0.696  -0.696  -0.696  -0.537  -0.537  -0.537
27    L        -0.537  -0.537  -0.537  -0.730  -0.730  -0.730  -0.537  -0.537  -0.537
28    N        -0.537  -0.537  -0.537  -0.211  -0.211  -0.211  -0.537  -0.537  -0.537
29    K        -0.537  -0.537  -0.537  -0.713  -0.713  -0.713  -0.537  -0.537  -0.537
30    K        -0.537  -0.537  -0.537  -0.452  -0.452  -0.452  -0.537  -0.537  -0.537
31    R        -0.537  -0.537  -0.537  -0.605  -0.605  -0.605  -0.537  -0.537  -0.537
32    R        -0.537  -0.537  -0.537  -0.249  -0.249  -0.249  -0.537  -0.537  -0.537
33    K        -0.537  -0.537  -0.537  -0.622  -0.622  -0.622  -0.537  -0.537  -0.537
34    Q        -0.537  -0.537  -0.537  -0.241  -0.241  -0.241  -0.537  -0.537  -0.537
35    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
36    V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
37    I        -0.537  -0.537  -0.537  -0.484  -0.484  -0.484  -0.537  -0.537  -0.537
38    I        -0.537  -0.537  -0.537  -1.089  -1.089  -1.089  -0.537  -0.537  -0.537
39    L        -0.537  -0.537  -0.537  -0.730  -0.730  -0.730  -0.537  -0.537  -0.537
40    K        -0.537  -0.537  -0.537  -0.622  -0.622  -0.622  -0.537  -0.537  -0.537
41    R         1.858   1.858   1.858   1.904   1.904   1.904   1.858   1.858   1.858
42    I         1.858   1.858   1.858   1.649   1.649   1.649   1.858   1.858   1.858
43    T        -0.537  -0.537  -0.537  -0.349  -0.349  -0.349  -0.537  -0.537  -0.537
44    Q        -0.537  -0.537  -0.537  -0.165  -0.165  -0.165  -0.537  -0.537  -0.537
45    V         1.858   1.858   1.858   1.893   1.893   1.893   1.858   1.858   1.858
46    Y        -0.537  -0.537  -0.537  -0.460  -0.460  -0.460  -0.537  -0.537  -0.537
47    G         1.858   1.858   1.858   2.066   2.066   2.066   1.858   1.858   1.858
48    I        -0.537  -0.537  -0.537  -0.614  -0.614  -0.614  -0.537  -0.537  -0.537
49    N         1.858   1.858   1.858   1.958   1.958   1.958   1.858   1.858   1.858
50    L        -0.537  -0.537  -0.537  -0.755  -0.755  -0.755  -0.537  -0.537  -0.537
51    V        -0.537  -0.537  -0.537  -0.460  -0.460  -0.460  -0.537  -0.537  -0.537
52    F        -0.537  -0.537  -0.537  -0.638  -0.638  -0.638  -0.537  -0.537  -0.537
53    Y        -0.537  -0.537  -0.537  -0.165  -0.165  -0.165  -0.537  -0.537  -0.537
54    V        -0.537  -0.537  -0.537  -0.893  -0.893  -0.893  -0.537  -0.537  -0.537
55    K        -0.537  -0.537  -0.537  -1.107  -1.107  -1.107  -0.537  -0.537  -0.537
56    K         1.858   1.858   1.858   1.627   1.627   1.627   1.858   1.858   1.858
57    W        -0.537  -0.537  -0.537  -0.420  -0.420  -0.420  -0.537  -0.537  -0.537
58    K        -0.537  -0.537  -0.537  -0.436  -0.436  -0.436  -0.537  -0.537  -0.537
59    L        -0.537  -0.537  -0.537  -0.884  -0.884  -0.884  -0.537  -0.537  -0.537
60    K         1.858   1.858   1.858   1.627   1.627   1.627   1.858   1.858   1.858
61    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
62    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
63    Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
64    G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
65    E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
66    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
67    I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
68    Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
69    I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
70    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
71    D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
72    I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
73    M        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
74    P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
75    W        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
76    L         1.858   1.858   1.858   1.268   1.268   1.268   1.858   1.858   1.858
77    R        -0.537  -0.537  -0.537  -0.342  -0.342  -0.342  -0.537  -0.537  -0.537
78    E        -0.537  -0.537  -0.537  -0.143  -0.143  -0.143  -0.537  -0.537  -0.537
79    S         1.858   1.858   1.858   1.783   1.783   1.783   1.858   1.858   1.858
80    T        -0.537  -0.537  -0.537  -0.428  -0.428  -0.428  -0.537  -0.537  -0.537
81    I        -0.537  -0.537  -0.537  -1.089  -1.089  -1.089  -0.537  -0.537  -0.537
82    L        -0.537  -0.537  -0.537  -0.919  -0.919  -0.919  -0.537  -0.537  -0.537
83    V        -0.537  -0.537  -0.537  -0.257  -0.257  -0.257  -0.537  -0.537  -0.537
84    L        -0.537  -0.537  -0.537  -0.755  -0.755  -0.755  -0.537  -0.537  -0.537
85    L         1.858   1.858   1.858   1.268   1.268   1.268   1.858   1.858   1.858
86    N        -0.537  -0.537  -0.537  -0.211  -0.211  -0.211  -0.537  -0.537  -0.537
87    I         1.858   1.858   1.858   1.649   1.649   1.649   1.858   1.858   1.858
88    L        -0.537  -0.537  -0.537  -0.893  -0.893  -0.893  -0.537  -0.537  -0.537
89    Y        -0.537  -0.537  -0.537  -0.287  -0.287  -0.287  -0.537  -0.537  -0.537
90    P        -0.537  -0.537  -0.537  -0.135  -0.135  -0.135  -0.537  -0.537  -0.537
91    T        -0.537  -0.537  -0.537  -0.524  -0.524  -0.524  -0.537  -0.537  -0.537
92    L        -0.537  -0.537  -0.537  -0.696  -0.696  -0.696  -0.537  -0.537  -0.537
93    M        -0.537  -0.537  -0.537  -0.647  -0.647  -0.647  -0.537  -0.537  -0.537
94    K        -0.537  -0.537  -0.537  -1.107  -1.107  -1.107  -0.537  -0.537  -0.537
95    F        -0.537  -0.537  -0.537  -0.452  -0.452  -0.452  -0.537  -0.537  -0.537
96    P        -0.537  -0.537  -0.537  -0.249  -0.249  -0.249  -0.537  -0.537  -0.537
97    F        -0.537  -0.537  -0.537  -0.638  -0.638  -0.638  -0.537  -0.537  -0.537
98    L        -0.537  -0.537  -0.537  -1.089  -1.089  -1.089  -0.537  -0.537  -0.537
99    K        -0.537  -0.537  -0.537  -0.622  -0.622  -0.622  -0.537  -0.537  -0.537
100   N        -0.537  -0.537  -0.537  -0.241  -0.241  -0.241  -0.537  -0.537  -0.537
101   H        -0.537  -0.537  -0.537  -0.241  -0.241  -0.241  -0.537  -0.537  -0.537
102   Y        -0.537  -0.537  -0.537  -0.105  -0.105  -0.105  -0.537  -0.537  -0.537
103   I        -0.537  -0.537  -0.537  -0.484  -0.484  -0.484  -0.537  -0.537  -0.537
104   H        -0.537  -0.537  -0.537  -0.326  -0.326  -0.326  -0.537  -0.537  -0.537
105   W         1.858   1.858   1.858   2.171   2.171   2.171   1.858   1.858   1.858
106   S        -0.537  -0.537  -0.537  -0.540  -0.540  -0.540  -0.537  -0.537  -0.537
107   S        -0.537  -0.537  -0.537  -0.981  -0.981  -0.981  -0.537  -0.537  -0.537
108   I        -0.537  -0.537  -0.537  -0.484  -0.484  -0.484  -0.537  -0.537  -0.537
109   V        -0.537  -0.537  -0.537  -0.893  -0.893  -0.893  -0.537  -0.537  -0.537
110   G        -0.537  -0.537  -0.537  -0.226  -0.226  -0.226  -0.537  -0.537  -0.537
111   I         1.858   1.858   1.858   1.649   1.649   1.649   1.858   1.858   1.858
112   S        -0.537  -0.537  -0.537  -0.389  -0.389  -0.389  -0.537  -0.537  -0.537
113   L         1.858   1.858   1.858   1.268   1.268   1.268   1.858   1.858   1.858
114   M        -0.537  -0.537  -0.537  -0.287  -0.287  -0.287  -0.537  -0.537  -0.537
115   L        -0.537  -0.537  -0.537  -0.730  -0.730  -0.730  -0.537  -0.537  -0.537
116   T        -0.537  -0.537  -0.537  -0.798  -0.798  -0.798  -0.537  -0.537  -0.537
117   K         1.858   1.858   1.858   1.627   1.627   1.627   1.858   1.858   1.858
118   G        -0.537  -0.537  -0.537  -0.188  -0.188  -0.188  -0.537  -0.537  -0.537
119   E        -0.537  -0.537  -0.537  -0.452  -0.452  -0.452  -0.537  -0.537  -0.537
120   V        -0.537  -0.537  -0.537  -0.893  -0.893  -0.893  -0.537  -0.537  -0.537
121   P         1.858   1.858   1.858   2.140   2.140   2.140   1.858   1.858   1.858
122   S        -0.537  -0.537  -0.537  -0.326  -0.326  -0.326  -0.537  -0.537  -0.537
123   W         1.858   1.858   1.858   2.171   2.171   2.171   1.858   1.858   1.858
124   I         1.858   1.858   1.858   1.649   1.649   1.649   1.858   1.858   1.858
125   I        -0.537  -0.537  -0.537  -0.614  -0.614  -0.614  -0.537  -0.537  -0.537
126   A        -0.537  -0.537  -0.537  -0.389  -0.389  -0.389  -0.537  -0.537  -0.537
127   H        -0.537  -0.537  -0.537  -0.105  -0.105  -0.105  -0.537  -0.537  -0.537
128   F        -0.537  -0.537  -0.537  -0.257  -0.257  -0.257  -0.537  -0.537  -0.537
129   L        -0.537  -0.537  -0.537  -0.755  -0.755  -0.755  -0.537  -0.537  -0.537
130   V         1.858   1.858   1.858   1.893   1.893   1.893   1.858   1.858   1.858
131   E         1.858   1.858   1.858   2.129   2.129   2.129   1.858   1.858   1.858
132   A        -0.537  -0.537  -0.537  -0.389  -0.389  -0.389  -0.537  -0.537  -0.537
133   I        -0.537  -0.537  -0.537  -0.614  -0.614  -0.614  -0.537  -0.537  -0.537
134   A        -0.537  -0.537  -0.537  -0.310  -0.310  -0.310  -0.537  -0.537  -0.537
135   S        -0.537  -0.537  -0.537  -0.334  -0.334  -0.334  -0.537  -0.537  -0.537
136   K        -0.537  -0.537  -0.537  -0.476  -0.476  -0.476  -0.537  -0.537  -0.537
137   L        -0.537  -0.537  -0.537  -1.089  -1.089  -1.089  -0.537  -0.537  -0.537
138   K         1.858   1.858   1.858   1.627   1.627   1.627   1.858   1.858   1.858
139   I        -0.537  -0.537  -0.537  -1.089  -1.089  -1.089  -0.537  -0.537  -0.537
140   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
141   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
142   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
143   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
144   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
145   W         1.858   1.858   1.858   2.171   2.171   2.171   1.858   1.858   1.858
146   L        -0.537  -0.537  -0.537  -0.893  -0.893  -0.893  -0.537  -0.537  -0.537
147   K        -0.537  -0.537  -0.537  -0.444  -0.444  -0.444  -0.537  -0.537  -0.537
148   K        -0.537  -0.537  -0.537  -0.476  -0.476  -0.476  -0.537  -0.537  -0.537
149   K        -0.537  -0.537  -0.537  -0.713  -0.713  -0.713  -0.537  -0.537  -0.537
150   N        -0.537  -0.537  -0.537  -0.468  -0.468  -0.468  -0.537  -0.537  -0.537
151   F        -0.537  -0.537  -0.537  -0.638  -0.638  -0.638  -0.537  -0.537  -0.537
152   S         1.858   1.858   1.858   1.783   1.783   1.783   1.858   1.858   1.858
153   Q        -0.537  -0.537  -0.537  -0.120  -0.120  -0.120  -0.537  -0.537  -0.537
154   G        -0.537  -0.537  -0.537  -0.303  -0.303  -0.303  -0.537  -0.537  -0.537
155   T        -0.537  -0.537  -0.537  -0.342  -0.342  -0.342  -0.537  -0.537  -0.537
156   L        -0.537  -0.537  -0.537  -0.671  -0.671  -0.671  -0.537  -0.537  -0.537
157   I         1.858   1.858   1.858   1.649   1.649   1.649   1.858   1.858   1.858
158   K        -0.537  -0.537  -0.537  -1.107  -1.107  -1.107  -0.537  -0.537  -0.537
159   F        -0.537  -0.537  -0.537  -0.919  -0.919  -0.919  -0.537  -0.537  -0.537
160   Q        -0.537  -0.537  -0.537  -0.280  -0.280  -0.280  -0.537  -0.537  -0.537
161   Q         1.858   1.858   1.858   2.097   2.097   2.097   1.858   1.858   1.858
162   I        -0.537  -0.537  -0.537  -1.089  -1.089  -1.089  -0.537  -0.537  -0.537
163   L        -0.537  -0.537  -0.537  -0.755  -0.755  -0.755  -0.537  -0.537  -0.537
164   V        -0.537  -0.537  -0.537  -0.310  -0.310  -0.310  -0.537  -0.537  -0.537
165   C        -0.537  -0.537  -0.537  -0.218  -0.218  -0.218  -0.537  -0.537  -0.537
166   L         1.858   1.858   1.858   1.268   1.268   1.268   1.858   1.858   1.858
167   A        -0.537  -0.537  -0.537  -0.755  -0.755  -0.755  -0.537  -0.537  -0.537
168   I         1.858   1.858   1.858   1.649   1.649   1.649   1.858   1.858   1.858
169   I        -0.537  -0.537  -0.537  -0.428  -0.428  -0.428  -0.537  -0.537  -0.537
170   V        -0.537  -0.537  -0.537  -0.614  -0.614  -0.614  -0.537  -0.537  -0.537
171   L         1.858   1.858   1.858   1.268   1.268   1.268   1.858   1.858   1.858
172   F        -0.537  -0.537  -0.537  -0.310  -0.310  -0.310  -0.537  -0.537  -0.537
173   A        -0.537  -0.537  -0.537  -0.128  -0.128  -0.128  -0.537  -0.537  -0.537
174   K        -0.537  -0.537  -0.537  -0.622  -0.622  -0.622  -0.537  -0.537  -0.537
175   L        -0.537  -0.537  -0.537  -0.841  -0.841  -0.841  -0.537  -0.537  -0.537
176   D        -0.537  -0.537  -0.537  -0.113  -0.113  -0.113  -0.537  -0.537  -0.537
177   R        -0.537  -0.537  -0.537  -0.508  -0.508  -0.508  -0.537  -0.537  -0.537
178   S        -0.537  -0.537  -0.537  -0.713  -0.713  -0.713  -0.537  -0.537  -0.537
179   S        -0.537  -0.537  -0.537  -0.389  -0.389  -0.389  -0.537  -0.537  -0.537
180   L        -0.537  -0.537  -0.537  -0.884  -0.884  -0.884  -0.537  -0.537  -0.537
181   P        -0.537  -0.537  -0.537  -0.696  -0.696  -0.696  -0.537  -0.537  -0.537
182   F        -0.537  -0.537  -0.537  -0.310  -0.310  -0.310  -0.537  -0.537  -0.537
183   R         1.858   1.858   1.858   1.904   1.904   1.904   1.858   1.858   1.858
184   V        -0.537  -0.537  -0.537  -0.614  -0.614  -0.614  -0.537  -0.537  -0.537
185   L         1.858   1.858   1.858   1.268   1.268   1.268   1.858   1.858   1.858
186   F         1.858   1.858   1.858   1.860   1.860   1.860   1.858   1.858   1.858
187   D        -0.537  -0.537  -0.537  -0.091  -0.091  -0.091  -0.537  -0.537  -0.537
188   H        -0.537  -0.537  -0.537  -0.165  -0.165  -0.165  -0.537  -0.537  -0.537
189   R         1.858   1.858   1.858   1.904   1.904   1.904   1.858   1.858   1.858
190   P        -0.537  -0.537  -0.537  -0.444  -0.444  -0.444  -0.537  -0.537  -0.537
191   F        -0.537  -0.537  -0.537  -0.280  -0.280  -0.280  -0.537  -0.537  -0.537
192   L        -0.537  -0.537  -0.537  -0.671  -0.671  -0.671  -0.537  -0.537  -0.537
193   I        -0.537  -0.537  -0.537  -0.815  -0.815  -0.815  -0.537  -0.537  -0.537
194   D         1.858   1.858   1.858   2.140   2.140   2.140   1.858   1.858   1.858
195   F         1.858   1.858   1.858   1.860   1.860   1.860   1.858   1.858   1.858
196   F        -0.537  -0.537  -0.537  -0.919  -0.919  -0.919  -0.537  -0.537  -0.537
197   T        -0.537  -0.537  -0.537  -0.798  -0.798  -0.798  -0.537  -0.537  -0.537
198   I        -0.537  -0.537  -0.537  -1.089  -1.089  -1.089  -0.537  -0.537  -0.537
199   N        -0.537  -0.537  -0.537  -0.412  -0.412  -0.412  -0.537  -0.537  -0.537
200   A        -0.537  -0.537  -0.537  -0.310  -0.310  -0.310  -0.537  -0.537  -0.537
201   I        -0.537  -0.537  -0.537  -0.484  -0.484  -0.484  -0.537  -0.537  -0.537
202   F        -0.537  -0.537  -0.537  -0.257  -0.257  -0.257  -0.537  -0.537  -0.537
203   T        -0.537  -0.537  -0.537  -0.303  -0.303  -0.303  -0.537  -0.537  -0.537
204   V         1.858   1.858   1.858   1.893   1.893   1.893   1.858   1.858   1.858
205   L        -0.537  -0.537  -0.537  -0.893  -0.893  -0.893  -0.537  -0.537  -0.537
206   A        -0.537  -0.537  -0.537  -0.500  -0.500  -0.500  -0.537  -0.537  -0.537
207   V        -0.537  -0.537  -0.537  -0.349  -0.349  -0.349  -0.537  -0.537  -0.537
208   Y         1.858   1.858   1.858   2.097   2.097   2.097   1.858   1.858   1.858
209   H        -0.537  -0.537  -0.537  -0.436  -0.436  -0.436  -0.537  -0.537  -0.537
210   R        -0.537  -0.537  -0.537  -0.381  -0.381  -0.381  -0.537  -0.537  -0.537
211   T        -0.537  -0.537  -0.537  -0.349  -0.349  -0.349  -0.537  -0.537  -0.537
212   L        -0.537  -0.537  -0.537  -1.107  -1.107  -1.107  -0.537  -0.537  -0.537
213   K        -0.537  -0.537  -0.537  -0.713  -0.713  -0.713  -0.537  -0.537  -0.537
214   F        -0.537  -0.537  -0.537  -0.638  -0.638  -0.638  -0.537  -0.537  -0.537
215   F        -0.537  -0.537  -0.537  -0.919  -0.919  -0.919  -0.537  -0.537  -0.537
216   F        -0.537  -0.537  -0.537  -0.919  -0.919  -0.919  -0.537  -0.537  -0.537
217   T        -0.537  -0.537  -0.537  -0.540  -0.540  -0.540  -0.537  -0.537  -0.537
218   S        -0.537  -0.537  -0.537  -0.342  -0.342  -0.342  -0.537  -0.537  -0.537
219   G        -0.537  -0.537  -0.537  -0.500  -0.500  -0.500  -0.537  -0.537  -0.537
220   T        -0.537  -0.537  -0.537  -0.798  -0.798  -0.798  -0.537  -0.537  -0.537
221   K         1.858   1.858   1.858   1.627   1.627   1.627   1.858   1.858   1.858
222   S        -0.537  -0.537  -0.537  -0.713  -0.713  -0.713  -0.537  -0.537  -0.537
223   N         1.858   1.858   1.858   1.958   1.958   1.958   1.858   1.858   1.858
224   K         1.858   1.858   1.858   1.627   1.627   1.627   1.858   1.858   1.858
225   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
226   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
227   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
228   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
229   H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
230   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
231   V         1.858   1.858   1.858   1.893   1.893   1.893   1.858   1.858   1.858
232   R        -0.537  -0.537  -0.537  -0.381  -0.381  -0.381  -0.537  -0.537  -0.537
233   N        -0.537  -0.537  -0.537  -0.303  -0.303  -0.303  -0.537  -0.537  -0.537
234   F        -0.537  -0.537  -0.537  -0.540  -0.540  -0.540  -0.537  -0.537  -0.537
235   S         1.858   1.858   1.858   1.783   1.783   1.783   1.858   1.858   1.858
236   Q        -0.537  -0.537  -0.537  -0.068  -0.068  -0.068  -0.537  -0.537  -0.537
237   Y        -0.537  -0.537  -0.537  -0.203  -0.203  -0.203  -0.537  -0.537  -0.537
238   L        -0.537  -0.537  -0.537  -0.919  -0.919  -0.919  -0.537  -0.537  -0.537
239   G        -0.537  -0.537  -0.537  -0.135  -0.135  -0.135  -0.537  -0.537  -0.537
240   V        -0.537  -0.537  -0.537  -0.516  -0.516  -0.516  -0.537  -0.537  -0.537
241   K        -0.537  -0.537  -0.537  -0.452  -0.452  -0.452  -0.537  -0.537  -0.537
242   N        -0.537  -0.537  -0.537  -0.264  -0.264  -0.264  -0.537  -0.537  -0.537
243   H        -0.537  -0.537  -0.537  -0.436  -0.436  -0.436  -0.537  -0.537  -0.537
244   N        -0.537  -0.537  -0.537  -0.218  -0.218  -0.218  -0.537  -0.537  -0.537
245   D        -0.537  -0.537  -0.537  -0.334  -0.334  -0.334  -0.537  -0.537  -0.537
246   W        -0.537  -0.537  -0.537  -0.091  -0.091  -0.091  -0.537  -0.537  -0.537
247   P        -0.537  -0.537  -0.537  -0.173  -0.173  -0.173  -0.537  -0.537  -0.537
248   I        -0.537  -0.537  -0.537  -0.460  -0.460  -0.460  -0.537  -0.537  -0.537
249   S        -0.537  -0.537  -0.537  -0.326  -0.326  -0.326  -0.537  -0.537  -0.537
250   S        -0.537  -0.537  -0.537  -0.389  -0.389  -0.389  -0.537  -0.537  -0.537
251   S         1.858   1.858   1.858   1.783   1.783   1.783   1.858   1.858   1.858
252   N        -0.537  -0.537  -0.537  -0.165  -0.165  -0.165  -0.537  -0.537  -0.537
253   L        -0.537  -0.537  -0.537  -0.798  -0.798  -0.798  -0.537  -0.537  -0.537
254   K        -0.537  -0.537  -0.537  -0.622  -0.622  -0.622  -0.537  -0.537  -0.537
255   H        -0.537  -0.537  -0.537  -0.420  -0.420  -0.420  -0.537  -0.537  -0.537
256   V        -0.537  -0.537  -0.537  -0.893  -0.893  -0.893  -0.537  -0.537  -0.537
257   M         1.858   1.858   1.858   2.203   2.203   2.203   1.858   1.858   1.858
258   D        -0.537  -0.537  -0.537  -0.113  -0.113  -0.113  -0.537  -0.537  -0.537
259   R         1.858   1.858   1.858   1.904   1.904   1.904   1.858   1.858   1.858
260   L         1.858   1.858   1.858   1.268   1.268   1.268   1.858   1.858   1.858
261   N        -0.537  -0.537  -0.537  -0.218  -0.218  -0.218  -0.537  -0.537  -0.537
262   E         1.858   1.858   1.858   2.129   2.129   2.129   1.858   1.858   1.858
263   I        -0.537  -0.537  -0.537  -1.089  -1.089  -1.089  -0.537  -0.537  -0.537
264   H        -0.537  -0.537  -0.537  -0.203  -0.203  -0.203  -0.537  -0.537  -0.537
265   E         1.858   1.858   1.858   2.129   2.129   2.129   1.858   1.858   1.858
266   V        -0.537  -0.537  -0.537  -0.893  -0.893  -0.893  -0.537  -0.537  -0.537
267   T        -0.537  -0.537  -0.537  -0.428  -0.428  -0.428  -0.537  -0.537  -0.537
268   I        -0.537  -0.537  -0.537  -0.428  -0.428  -0.428  -0.537  -0.537  -0.537
269   D        -0.537  -0.537  -0.537  -0.444  -0.444  -0.444  -0.537  -0.537  -0.537
270   D        -0.537  -0.537  -0.537  -0.444  -0.444  -0.444  -0.537  -0.537  -0.537
271   N        -0.537  -0.537  -0.537  -0.468  -0.468  -0.468  -0.537  -0.537  -0.537
272   Y        -0.537  -0.537  -0.537  -0.365  -0.365  -0.365  -0.537  -0.537  -0.537
273   A        -0.537  -0.537  -0.537  -0.188  -0.188  -0.188  -0.537  -0.537  -0.537
274   N        -0.537  -0.537  -0.537  -0.468  -0.468  -0.468  -0.537  -0.537  -0.537
275   I        -0.537  -0.537  -0.537  -0.614  -0.614  -0.614  -0.537  -0.537  -0.537
276   N        -0.537  -0.537  -0.537  -0.581  -0.581  -0.581  -0.537  -0.537  -0.537
277   E         1.858   1.858   1.858   2.129   2.129   2.129   1.858   1.858   1.858
278   K        -0.537  -0.537  -0.537  -0.622  -0.622  -0.622  -0.537  -0.537  -0.537
279   I        -0.537  -0.537  -0.537  -0.614  -0.614  -0.614  -0.537  -0.537  -0.537
280   I        -0.537  -0.537  -0.537  -0.460  -0.460  -0.460  -0.537  -0.537  -0.537
281   N        -0.537  -0.537  -0.537  -0.264  -0.264  -0.264  -0.537  -0.537  -0.537
282   S        -0.537  -0.537  -0.537  -0.365  -0.365  -0.365  -0.537  -0.537  -0.537
283   Y        -0.537  -0.537  -0.537  -0.310  -0.310  -0.310  -0.537  -0.537  -0.537
284   F         1.858   1.858   1.858   1.860   1.860   1.860   1.858   1.858   1.858
285   T        -0.537  -0.537  -0.537  -0.428  -0.428  -0.428  -0.537  -0.537  -0.537
286   K        -0.537  -0.537  -0.537  -0.444  -0.444  -0.444  -0.537  -0.537  -0.537
287   G        -0.537  -0.537  -0.537  -0.264  -0.264  -0.264  -0.537  -0.537  -0.537
288   F         1.858   1.858   1.858   1.860   1.860   1.860   1.858   1.858   1.858
289   F        -0.537  -0.537  -0.537  -0.638  -0.638  -0.638  -0.537  -0.537  -0.537
290   P        -0.537  -0.537  -0.537  -0.444  -0.444  -0.444  -0.537  -0.537  -0.537
291   S        -0.537  -0.537  -0.537  -0.218  -0.218  -0.218  -0.537  -0.537  -0.537
292   L        -0.537  -0.537  -0.537  -0.893  -0.893  -0.893  -0.537  -0.537  -0.537
293   K         1.858   1.858   1.858   1.627   1.627   1.627   1.858   1.858   1.858
294   W         1.858   1.858   1.858   2.171   2.171   2.171   1.858   1.858   1.858
295   T         1.858   1.858   1.858   2.012   2.012   2.012   1.858   1.858   1.858
296   I        -0.537  -0.537  -0.537  -1.089  -1.089  -1.089  -0.537  -0.537  -0.537
297   L        -0.537  -0.537  -0.537  -0.671  -0.671  -0.671  -0.537  -0.537  -0.537
298   R         1.858   1.858   1.858   1.904   1.904   1.904   1.858   1.858   1.858
299   Q         1.858   1.858   1.858   2.097   2.097   2.097   1.858   1.858   1.858
300   C        -0.537  -0.537  -0.537  -0.143  -0.143  -0.143  -0.537  -0.537  -0.537
301   I        -0.537  -0.537  -0.537  -0.614  -0.614  -0.614  -0.537  -0.537  -0.537
302   E        -0.537  -0.537  -0.537  -0.046  -0.046  -0.046  -0.537  -0.537  -0.537
303   Y        -0.537  -0.537  -0.537  -0.730  -0.730  -0.730  -0.537  -0.537  -0.537
304   L        -0.537  -0.537  -0.537  -1.089  -1.089  -1.089  -0.537  -0.537  -0.537
305   F         1.858   1.858   1.858   1.860   1.860   1.860   1.858   1.858   1.858
306   V        -0.537  -0.537  -0.537  -0.389  -0.389  -0.389  -0.537  -0.537  -0.537
307   T        -0.537  -0.537  -0.537  -0.226  -0.226  -0.226  -0.537  -0.537  -0.537
308   K        -0.537  -0.537  -0.537  -0.476  -0.476  -0.476  -0.537  -0.537  -0.537
309   R        -0.537  -0.537  -0.537  -0.241  -0.241  -0.241  -0.537  -0.537  -0.537
310   R        -0.537  -0.537  -0.537  -0.508  -0.508  -0.508  -0.537  -0.537  -0.537
311   R        -0.537  -0.537  -0.537  -0.622  -0.622  -0.622  -0.537  -0.537  -0.537
312   L        -0.537  -0.537  -0.537  -0.573  -0.573  -0.573  -0.537  -0.537  -0.537
313   M        -0.537  -0.537  -0.537  -0.647  -0.647  -0.647  -0.537  -0.537  -0.537
314   G        -0.537  -0.537  -0.537  -0.500  -0.500  -0.500  -0.537  -0.537  -0.537
315   N        -0.537  -0.537  -0.537  -0.211  -0.211  -0.211  -0.537  -0.537  -0.537
316   K        -0.537  -0.537  -0.537  -1.107  -1.107  -1.107  -0.537  -0.537  -0.537
317   L        -0.537  -0.537  -0.537  -0.688  -0.688  -0.688  -0.537  -0.537  -0.537
318   R        -0.537  -0.537  -0.537  -0.622  -0.622  -0.622  -0.537  -0.537  -0.537
319   C        -0.537  -0.537  -0.537  -0.218  -0.218  -0.218  -0.537  -0.537  -0.537
320   I         1.858   1.858   1.858   1.649   1.649   1.649   1.858   1.858   1.858
321   V        -0.537  -0.537  -0.537  -0.614  -0.614  -0.614  -0.537  -0.537  -0.537
322   M        -0.537  -0.537  -0.537  -0.381  -0.381  -0.381  -0.537  -0.537  -0.537
323   L        -0.537  -0.537  -0.537  -0.647  -0.647  -0.647  -0.537  -0.537  -0.537
324   L         1.858   1.858   1.858   1.268   1.268   1.268   1.858   1.858   1.858
325   T        -0.537  -0.537  -0.537  -0.428  -0.428  -0.428  -0.537  -0.537  -0.537
326   F         1.858   1.858   1.858   1.860   1.860   1.860   1.858   1.858   1.858
327   T         1.858   1.858   1.858   2.012   2.012   2.012   1.858   1.858   1.858
328   F        -0.537  -0.537  -0.537  -0.919  -0.919  -0.919  -0.537  -0.537  -0.537
329   V        -0.537  -0.537  -0.537  -0.893  -0.893  -0.893  -0.537  -0.537  -0.537
330   D        -0.537  -0.537  -0.537  -0.334  -0.334  -0.334  -0.537  -0.537  -0.537
331   P        -0.537  -0.537  -0.537  -0.083  -0.083  -0.083  -0.537  -0.537  -0.537
332   T        -0.537  -0.537  -0.537  -0.173  -0.173  -0.173  -0.537  -0.537  -0.537
333   S        -0.537  -0.537  -0.537  -0.365  -0.365  -0.365  -0.537  -0.537  -0.537
334   K        -0.537  -0.537  -0.537  -0.436  -0.436  -0.436  -0.537  -0.537  -0.537
335   M        -0.537  -0.537  -0.537  -0.647  -0.647  -0.647  -0.537  -0.537  -0.537
336   K        -0.537  -0.537  -0.537  -0.444  -0.444  -0.444  -0.537  -0.537  -0.537
337   I         1.858   1.858   1.858   1.649   1.649   1.649   1.858   1.858   1.858
338   S        -0.537  -0.537  -0.537  -0.468  -0.468  -0.468  -0.537  -0.537  -0.537
339   P        -0.537  -0.537  -0.537  -0.061  -0.061  -0.061  -0.537  -0.537  -0.537
340   F        -0.537  -0.537  -0.537  -0.287  -0.287  -0.287  -0.537  -0.537  -0.537
341   F        -0.537  -0.537  -0.537  -0.919  -0.919  -0.919  -0.537  -0.537  -0.537
342   A        -0.537  -0.537  -0.537  -0.755  -0.755  -0.755  -0.537  -0.537  -0.537
343   K         1.858   1.858   1.858   1.627   1.627   1.627   1.858   1.858   1.858
344   F        -0.537  -0.537  -0.537  -0.310  -0.310  -0.310  -0.537  -0.537  -0.537
345   F        -0.537  -0.537  -0.537  -0.919  -0.919  -0.919  -0.537  -0.537  -0.537
346   A        -0.537  -0.537  -0.537  -0.188  -0.188  -0.188  -0.537  -0.537  -0.537
347   K        -0.537  -0.537  -0.537  -0.622  -0.622  -0.622  -0.537  -0.537  -0.537
348   S         1.858   1.858   1.858   1.783   1.783   1.783   1.858   1.858   1.858
349   L        -0.537  -0.537  -0.537  -0.798  -0.798  -0.798  -0.537  -0.537  -0.537
350   V        -0.537  -0.537  -0.537  -0.893  -0.893  -0.893  -0.537  -0.537  -0.537
351   N        -0.537  -0.537  -0.537  -0.468  -0.468  -0.468  -0.537  -0.537  -0.537
352   V        -0.537  -0.537  -0.537  -0.287  -0.287  -0.287  -0.537  -0.537  -0.537
353   Y        -0.537  -0.537  -0.537  -0.120  -0.120  -0.120  -0.537  -0.537  -0.537
354   L         1.858   1.858   1.858   1.268   1.268   1.268   1.858   1.858   1.858
355   K        -0.537  -0.537  -0.537  -0.500  -0.500  -0.500  -0.537  -0.537  -0.537
356   K        -0.537  -0.537  -0.537  -0.622  -0.622  -0.622  -0.537  -0.537  -0.537
357   Y        -0.537  -0.537  -0.537  -0.460  -0.460  -0.460  -0.537  -0.537  -0.537
358   W        -0.537  -0.537  -0.537  -0.061  -0.061  -0.061  -0.537  -0.537  -0.537
359   H         1.858   1.858   1.858   2.150   2.150   2.150   1.858   1.858   1.858
360   C        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
361   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
362   F        -0.537  -0.537  -0.537  -0.310  -0.310  -0.310  -0.537  -0.537  -0.537
363   G        -0.537  -0.537  -0.537  -0.165  -0.165  -0.165  -0.537  -0.537  -0.537
364   K         1.858   1.858   1.858   1.627   1.627   1.627   1.858   1.858   1.858
365   Y        -0.537  -0.537  -0.537  -0.113  -0.113  -0.113  -0.537  -0.537  -0.537
366   I         1.858   1.858   1.858   1.649   1.649   1.649   1.858   1.858   1.858
367   L        -0.537  -0.537  -0.537  -1.089  -1.089  -1.089  -0.537  -0.537  -0.537
368   F         1.858   1.858   1.858   1.860   1.860   1.860   1.858   1.858   1.858
369   F        -0.537  -0.537  -0.537  -0.334  -0.334  -0.334  -0.537  -0.537  -0.537
370   L        -0.537  -0.537  -0.537  -0.755  -0.755  -0.755  -0.537  -0.537  -0.537
371   F        -0.537  -0.537  -0.537  -0.919  -0.919  -0.919  -0.537  -0.537  -0.537
372   Q        -0.537  -0.537  -0.537  -0.365  -0.365  -0.365  -0.537  -0.537  -0.537
373   L         1.858   1.858   1.858   1.268   1.268   1.268   1.858   1.858   1.858
374   S         1.858   1.858   1.858   1.783   1.783   1.783   1.858   1.858   1.858
375   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
376   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
377   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
378   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
379   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
380   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
381   I         1.858   1.858   1.858   1.649   1.649   1.649   1.858   1.858   1.858
382   M        -0.537  -0.537  -0.537  -0.091  -0.091  -0.091  -0.537  -0.537  -0.537
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P53293
Output conservation file - output/P53293
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
