1     M         1.963   1.972   2.015   2.303   2.318   2.386   2.170   2.182   2.248
2     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
19    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
20    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
21    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
22    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
23    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
24    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
25    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
26    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
27    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
28    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
29    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
30    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
31    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
32    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
33    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
34    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
35    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
36    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
37    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
38    D        -0.482  -0.494  -0.510  -0.511  -0.530  -0.565  -0.518  -0.533  -0.545
39    F        -0.482  -0.493  -0.506  -0.181  -0.194  -0.197  -0.518  -0.531  -0.539
40    Y        -1.297  -1.295  -1.265  -0.961  -0.956  -0.906  -1.055  -1.050  -1.000
41    K        -0.482  -0.464  -0.495  -0.751  -0.704  -0.806  -0.518  -0.493  -0.525
42    L        -1.297  -1.295  -1.265  -0.872  -0.866  -0.816  -1.055  -1.050  -1.000
43    D        -1.297  -1.295  -1.265  -1.301  -1.292  -1.249  -1.055  -1.050  -1.000
44    E        -0.482  -0.526  -0.505  -0.688  -0.754  -0.741  -0.518  -0.573  -0.537
45    K         1.963   1.972   2.015   1.479   1.488   1.554   2.170   2.182   2.248
46    L         1.963   1.972   2.015   2.030   2.045   2.110   2.170   2.182   2.248
47    K         0.641   0.585   0.551   0.223   0.143   0.097   0.557   0.464   0.396
48    E        -1.297  -1.295  -1.265  -1.224  -1.208  -1.172  -1.055  -1.050  -1.000
49    L         1.963   1.972   2.015   2.030   2.045   2.110   2.170   2.182   2.248
50    K         0.641   0.631   0.572   0.223   0.209   0.128   0.557   0.541   0.433
51    R         0.333   0.336   0.376  -0.144  -0.130  -0.072   0.020   0.025   0.083
52    K        -0.482  -0.466  -0.493  -0.880  -0.857  -0.883  -0.518  -0.494  -0.522
53    R        -0.482  -0.429  -0.490  -0.761  -0.700  -0.750  -0.518  -0.446  -0.519
54    V         0.333   0.336   0.376   0.371   0.376   0.436   0.020   0.025   0.084
55    D         0.333   0.340   0.376   0.054   0.064   0.117   0.020   0.032   0.083
56    V         0.466   0.463   0.449   0.685   0.682   0.654   0.259   0.253   0.217
57    S         0.466   0.463   0.449   0.134   0.125   0.055   0.259   0.253   0.217
58    I         1.963   1.972   2.015   2.187   2.201   2.269   2.170   2.182   2.248
59    K         0.466   0.480   0.454   0.235   0.265   0.165   0.259   0.283   0.224
60    S         0.333   0.336   0.376   0.098   0.100   0.163   0.020   0.025   0.083
61    R        -0.482  -0.526  -0.505  -0.647  -0.738  -0.727  -0.518  -0.573  -0.537
62    K         0.641   0.683   0.566   0.173   0.232   0.055   0.557   0.628   0.423
63    L         0.641   0.631   0.572   0.799   0.790   0.704   0.557   0.541   0.433
64    A        -1.297  -1.295  -1.265  -0.984  -0.988  -0.929  -1.055  -1.050  -1.000
65    D         0.466   0.480   0.463  -0.082  -0.062  -0.089   0.259   0.283   0.242
66    R         0.466   0.480   0.463   0.450   0.474   0.439   0.259   0.283   0.242
67    E         1.963   1.972   2.015   1.859   1.872   1.938   2.170   2.182   2.248
68    I        -0.482  -0.494  -0.510  -0.160  -0.182  -0.206  -0.518  -0.533  -0.545
69    Q        -1.297  -1.295  -1.265  -0.939  -0.911  -0.884  -1.055  -1.050  -1.000
70    E         0.641   0.585   0.551   0.600   0.517   0.464   0.557   0.464   0.396
71    V        -1.297  -1.295  -1.265  -1.467  -1.453  -1.417  -1.055  -1.050  -1.000
72    S        -1.297  -1.295  -1.265  -1.426  -1.402  -1.375  -1.055  -1.050  -1.000
73    A         0.641   0.686   0.569   0.265   0.324   0.177   0.557   0.631   0.428
74    N        -0.482  -0.494  -0.510  -0.347  -0.374  -0.373  -0.518  -0.533  -0.545
75    R        -1.297  -1.295  -1.265  -1.109  -1.101  -1.056  -1.055  -1.050  -1.000
76    K         0.641   0.631   0.572   0.149   0.131   0.035   0.557   0.541   0.433
77    P        -0.482  -0.526  -0.505  -0.103  -0.176  -0.149  -0.518  -0.573  -0.537
78    R         0.641   0.585   0.551   0.614   0.509   0.415   0.557   0.464   0.396
79    V         0.641   0.585   0.551   0.876   0.789   0.721   0.557   0.464   0.396
80    Y         0.641   0.585   0.551   1.020   0.942   0.888   0.557   0.464   0.396
81    S         0.641   0.585   0.551   0.619   0.530   0.460   0.557   0.464   0.396
82    M         0.641   0.585   0.551   1.083   1.006   0.955   0.557   0.464   0.396
83    E        -1.297  -1.295  -1.265  -1.212  -1.237  -1.159  -1.055  -1.050  -1.000
84    D         0.641   0.585   0.551   0.505   0.401   0.307   0.557   0.464   0.396
85    V        -0.482  -0.493  -0.506  -0.288  -0.297  -0.307  -0.518  -0.531  -0.539
86    N        -0.482  -0.464  -0.495  -0.463  -0.433  -0.474  -0.518  -0.493  -0.525
87    D        -0.482  -0.526  -0.505  -0.488  -0.554  -0.530  -0.518  -0.573  -0.537
88    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
89    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
90    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
91    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
92    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
93    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
94    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
95    A        -0.621  -0.620  -0.584  -0.640  -0.640  -0.582  -0.697  -0.694  -0.640
96    D         0.641   0.585   0.551   0.692   0.612   0.555   0.557   0.464   0.396
97    E         0.641   0.631   0.572   0.408   0.388   0.256   0.557   0.541   0.433
98    -         0.466   0.473   0.463   0.021   0.030   0.031   0.259   0.270   0.242
99    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
100   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
101   S         0.333   0.336   0.376   0.200   0.207   0.264   0.020   0.025   0.083
102   V        -0.482  -0.493  -0.506  -0.294  -0.304  -0.313  -0.518  -0.531  -0.539
103   G        -1.297  -1.295  -1.265  -1.179  -1.191  -1.125  -1.055  -1.050  -1.000
104   D         0.333   0.340   0.376  -0.232  -0.241  -0.178   0.020   0.032   0.083
105   T        -1.297  -1.295  -1.265  -0.996  -0.978  -0.941  -1.055  -1.050  -1.000
106   E         0.641   0.683   0.566   0.600   0.662   0.489   0.557   0.628   0.423
107   S        -0.482  -0.526  -0.505  -0.337  -0.397  -0.359  -0.518  -0.573  -0.537
108   P        -1.297  -1.295  -1.265  -0.916  -0.902  -0.861  -1.055  -1.050  -1.000
109   E        -0.482  -0.466  -0.493  -0.421  -0.402  -0.426  -0.518  -0.494  -0.522
110   K        -0.482  -0.464  -0.495  -0.434  -0.384  -0.467  -0.518  -0.493  -0.525
111   E        -1.297  -1.295  -1.265  -1.271  -1.294  -1.219  -1.055  -1.050  -1.000
112   K        -0.482  -0.494  -0.510  -0.891  -0.906  -0.914  -0.518  -0.533  -0.545
113   A        -0.482  -0.493  -0.506  -0.347  -0.372  -0.383  -0.518  -0.531  -0.539
114   F        -0.482  -0.526  -0.505   0.074   0.019   0.051  -0.518  -0.573  -0.537
115   H        -1.297  -1.295  -1.265  -0.988  -1.000  -0.933  -1.055  -1.050  -1.000
116   Y         0.641   0.585   0.551   1.079   1.007   0.964   0.557   0.464   0.396
117   T         0.641   0.631   0.572   0.943   0.934   0.826   0.557   0.541   0.433
118   V         0.333   0.340   0.376   0.466   0.481   0.534   0.020   0.032   0.083
119   Q        -0.482  -0.526  -0.505  -0.393  -0.472  -0.439  -0.518  -0.573  -0.537
120   E         0.333   0.336   0.376   0.054   0.063   0.121   0.020   0.025   0.084
121   Y        -0.482  -0.494  -0.510   0.096   0.088   0.075  -0.518  -0.533  -0.545
122   D        -0.482  -0.429  -0.490  -0.469  -0.391  -0.474  -0.518  -0.446  -0.519
123   A        -0.482  -0.429  -0.490  -0.818  -0.752  -0.812  -0.518  -0.446  -0.519
124   W         1.963   1.972   2.015   2.385   2.399   2.468   2.170   2.182   2.248
125   E         1.963   1.972   2.015   1.862   1.874   1.941   2.170   2.182   2.248
126   R        -0.482  -0.464  -0.495  -0.765  -0.741  -0.759  -0.518  -0.493  -0.525
127   R         0.333   0.340   0.376  -0.144  -0.158  -0.091   0.020   0.032   0.083
128   H        -0.482  -0.429  -0.490  -0.020   0.065  -0.025  -0.518  -0.446  -0.519
129   P        -0.482  -0.493  -0.506  -0.434  -0.485  -0.487  -0.518  -0.531  -0.539
130   Q        -0.482  -0.466  -0.493  -0.365  -0.342  -0.387  -0.518  -0.494  -0.522
131   G        -0.482  -0.464  -0.495  -0.790  -0.774  -0.786  -0.518  -0.493  -0.525
132   K        -0.482  -0.526  -0.505  -0.733  -0.770  -0.732  -0.518  -0.573  -0.537
133   T        -1.297  -1.295  -1.265  -1.054  -1.028  -1.000  -1.055  -1.050  -1.000
134   G        -0.482  -0.429  -0.490  -0.396  -0.323  -0.402  -0.518  -0.446  -0.519
135   Q         0.333   0.336   0.376  -0.144  -0.133  -0.072   0.020   0.025   0.083
136   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
137   S         0.466   0.463   0.449   0.305   0.299   0.255   0.259   0.253   0.217
138   Q        -0.621  -0.621  -0.584  -0.502  -0.499  -0.444  -0.697  -0.695  -0.640
139   R        -0.482  -0.464  -0.495  -0.702  -0.678  -0.690  -0.518  -0.493  -0.525
140   G         0.333   0.336   0.376   0.330   0.334   0.392   0.020   0.025   0.084
141   G         1.963   1.972   2.015   2.267   2.282   2.349   2.170   2.182   2.248
142   I        -0.621  -0.620  -0.584  -0.141  -0.135  -0.079  -0.697  -0.694  -0.640
143   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
144   S        -1.297  -1.295  -1.265  -1.228  -1.228  -1.176  -1.055  -1.050  -1.000
145   Y        -0.482  -0.429  -0.490  -0.037   0.053  -0.049  -0.518  -0.446  -0.519
146   D        -0.482  -0.493  -0.506  -0.412  -0.436  -0.462  -0.518  -0.531  -0.539
147   Q        -1.297  -1.295  -1.265  -1.054  -1.083  -1.000  -1.055  -1.050  -1.000
148   L        -0.482  -0.526  -0.505  -0.178  -0.227  -0.192  -0.518  -0.573  -0.537
149   A         1.963   1.972   2.015   2.178   2.195   2.260   2.170   2.182   2.248
150   K         0.641   0.585   0.551   0.149   0.059  -0.001   0.557   0.464   0.396
151   L        -0.482  -0.493  -0.506  -0.440  -0.461  -0.473  -0.518  -0.531  -0.539
152   S        -0.482  -0.494  -0.510  -0.273  -0.285  -0.294  -0.518  -0.533  -0.545
153   Y         1.963   1.972   2.015   2.255   2.270   2.337   2.170   2.182   2.248
154   E        -1.297  -1.295  -1.265  -1.642  -1.646  -1.593  -1.055  -1.050  -1.000
155   K         1.963   1.972   2.015   1.479   1.488   1.554   2.170   2.182   2.248
156   T         0.641   0.686   0.569   0.664   0.726   0.574   0.557   0.631   0.428
157   L         0.641   0.631   0.572   0.801   0.792   0.707   0.557   0.541   0.433
158   R        -1.297  -1.295  -1.265  -1.105  -1.099  -1.052  -1.055  -1.050  -1.000
159   N         0.641   0.631   0.572   0.702   0.684   0.609   0.557   0.541   0.433
160   L         1.963   1.972   2.015   2.030   2.045   2.110   2.170   2.182   2.248
161   A        -0.482  -0.493  -0.506  -0.270  -0.315  -0.342  -0.518  -0.531  -0.539
162   T        -1.297  -1.295  -1.265  -1.162  -1.159  -1.109  -1.055  -1.050  -1.000
163   Q        -0.482  -0.429  -0.490  -0.285  -0.210  -0.284  -0.518  -0.446  -0.519
164   T        -1.297  -1.295  -1.265  -1.271  -1.295  -1.219  -1.055  -1.050  -1.000
165   Q        -1.297  -1.295  -1.265  -1.062  -1.075  -1.008  -1.055  -1.050  -1.000
166   N        -1.297  -1.295  -1.265  -1.130  -1.086  -1.076  -1.055  -1.050  -1.000
167   S        -0.621  -0.620  -0.584  -0.318  -0.310  -0.258  -0.697  -0.694  -0.640
168   S        -0.621  -0.620  -0.584  -1.036  -1.028  -0.982  -0.697  -0.694  -0.640
169   K        -0.621  -0.620  -0.584  -0.848  -0.842  -0.792  -0.697  -0.694  -0.640
170   Q         0.466   0.478   0.465   0.193   0.216   0.154   0.259   0.279   0.245
171   D        -0.621  -0.620  -0.584  -1.110  -1.119  -1.056  -0.697  -0.694  -0.640
172   S        -0.621  -0.620  -0.584  -0.535  -0.534  -0.476  -0.697  -0.694  -0.640
173   S        -0.621  -0.620  -0.584  -0.553  -0.544  -0.495  -0.697  -0.694  -0.640
174   A        -0.621  -0.620  -0.584  -0.217  -0.212  -0.156  -0.697  -0.694  -0.640
175   D        -0.621  -0.620  -0.584  -0.671  -0.670  -0.614  -0.697  -0.694  -0.640
176   E        -0.621  -0.620  -0.584  -0.916  -0.928  -0.861  -0.697  -0.694  -0.640
177   E         0.466   0.480   0.463   0.329   0.352   0.307   0.259   0.283   0.242
178   D         0.466   0.480   0.463  -0.082  -0.062  -0.089   0.259   0.283   0.242
179   N        -0.621  -0.620  -0.584  -0.723  -0.720  -0.666  -0.697  -0.694  -0.640
180   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
181   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
182   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
183   P         0.466   0.451   0.449   0.750   0.726   0.708   0.259   0.232   0.217
184   K        -0.621  -0.620  -0.584  -0.871  -0.862  -0.815  -0.697  -0.694  -0.640
185   K         0.466   0.451   0.449   0.107   0.092   0.109   0.259   0.232   0.217
186   G         0.466   0.451   0.449   0.610   0.583   0.561   0.259   0.232   0.217
187   R        -0.621  -0.620  -0.584  -0.776  -0.787  -0.719  -0.697  -0.694  -0.640
188   I         1.963   1.972   2.015   2.187   2.202   2.269   2.170   2.182   2.248
189   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
190   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
191   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
192   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
193   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
194   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
195   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
196   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
197   T        -0.482  -0.464  -0.495  -0.368  -0.341  -0.380  -0.518  -0.493  -0.525
198   G         0.641   0.585   0.551   0.930   0.842   0.774   0.557   0.464   0.396
199   K         1.963   1.972   2.015   1.479   1.488   1.554   2.170   2.182   2.248
200   I        -0.482  -0.493  -0.506  -0.043  -0.050  -0.064  -0.518  -0.531  -0.539
201   T        -1.297  -1.295  -1.265  -1.058  -1.061  -1.004  -1.055  -1.050  -1.000
202   I        -0.482  -0.526  -0.505  -0.097  -0.158  -0.125  -0.518  -0.573  -0.537
203   A        -0.482  -0.466  -0.493  -0.540  -0.495  -0.595  -0.518  -0.494  -0.522
204   D         1.963   1.972   2.015   1.957   1.973   2.037   2.170   2.182   2.248
205   D         0.466   0.480   0.454   0.411   0.436   0.375   0.259   0.283   0.224
206   D        -0.621  -0.621  -0.584  -0.808  -0.808  -0.751  -0.697  -0.695  -0.640
207   K         0.466   0.480   0.454   0.040   0.068  -0.027   0.259   0.283   0.224
208   L         1.963   1.972   2.015   2.015   2.027   2.095   2.170   2.182   2.248
209   V         0.641   0.585   0.551   0.972   0.898   0.847   0.557   0.464   0.396
210   N        -0.482  -0.466  -0.493  -0.514  -0.497  -0.535  -0.518  -0.494  -0.522
211   K         0.333   0.336   0.376  -0.144  -0.129  -0.070   0.020   0.025   0.084
212   L         0.641   0.631   0.572   0.840   0.832   0.755   0.557   0.541   0.433
213   A        -0.482  -0.429  -0.490  -0.205  -0.113  -0.220  -0.518  -0.446  -0.519
214   V        -1.297  -1.295  -1.265  -1.034  -1.036  -0.980  -1.055  -1.050  -1.000
215   S        -0.482  -0.464  -0.495  -0.524  -0.497  -0.550  -0.518  -0.493  -0.525
216   L         0.641   0.585   0.551   0.806   0.730   0.680   0.557   0.464   0.396
217   Q        -1.297  -1.295  -1.265  -1.568  -1.562  -1.518  -1.055  -1.050  -1.000
218   S         0.641   0.686   0.569   0.561   0.630   0.445   0.557   0.631   0.428
219   E        -1.297  -1.295  -1.265  -0.969  -0.952  -0.914  -1.055  -1.050  -1.000
220   S        -0.482  -0.494  -0.510  -0.415  -0.442  -0.455  -0.518  -0.533  -0.545
221   K         0.641   0.585   0.551   0.173   0.084   0.031   0.557   0.464   0.396
222   K        -0.482  -0.494  -0.510  -0.822  -0.835  -0.836  -0.518  -0.533  -0.545
223   R         1.963   1.972   2.015   2.065   2.081   2.146   2.170   2.182   2.248
224   Y         1.963   1.972   2.015   2.257   2.272   2.339   2.170   2.182   2.248
225   E        -0.482  -0.429  -0.490  -0.231  -0.127  -0.261  -0.518  -0.446  -0.519
226   A        -1.297  -1.295  -1.265  -1.275  -1.298  -1.223  -1.055  -1.050  -1.000
227   R         1.963   1.972   2.015   2.067   2.080   2.147   2.170   2.182   2.248
228   K        -0.482  -0.494  -0.510  -0.891  -0.904  -0.914  -0.518  -0.533  -0.545
229   R         0.641   0.631   0.572   0.797   0.785   0.692   0.557   0.541   0.433
230   Q        -0.482  -0.493  -0.506  -0.891  -0.916  -0.909  -0.518  -0.531  -0.539
231   M        -1.297  -1.295  -1.265  -1.146  -1.183  -1.092  -1.055  -1.050  -1.000
232   Q        -0.482  -0.429  -0.490  -0.350  -0.268  -0.354  -0.518  -0.446  -0.519
233   N        -0.482  -0.526  -0.505  -0.733  -0.821  -0.803  -0.518  -0.573  -0.537
234   A        -1.297  -1.295  -1.265  -1.134  -1.137  -1.080  -1.055  -1.050  -1.000
235   K         0.333   0.340   0.376  -0.256  -0.230  -0.186   0.020   0.032   0.083
236   T        -1.297  -1.295  -1.265  -1.421  -1.426  -1.370  -1.055  -1.050  -1.000
237   L        -0.621  -0.621  -0.584  -0.311  -0.305  -0.250  -0.697  -0.695  -0.640
238   Y        -0.621  -0.621  -0.584  -0.334  -0.331  -0.274  -0.697  -0.695  -0.640
239   G        -0.621  -0.621  -0.584  -0.521  -0.521  -0.462  -0.697  -0.695  -0.640
240   V        -0.482  -0.466  -0.493  -0.264  -0.231  -0.290  -0.518  -0.494  -0.522
241   E        -1.297  -1.295  -1.265  -1.349  -1.343  -1.298  -1.055  -1.050  -1.000
242   S         0.333   0.336   0.376   0.330   0.335   0.393   0.020   0.025   0.083
243   F        -0.482  -0.494  -0.510  -0.068  -0.076  -0.119  -0.518  -0.533  -0.545
244   I         1.963   1.972   2.015   2.199   2.213   2.281   2.170   2.182   2.248
245   N         1.963   1.972   2.015   1.928   1.934   2.007   2.170   2.182   2.248
246   D         0.641   0.683   0.566   0.730   0.795   0.627   0.557   0.628   0.423
247   K         1.963   1.972   2.015   1.479   1.488   1.554   2.170   2.182   2.248
248   N         1.963   1.972   2.015   1.928   1.934   2.007   2.170   2.182   2.248
249   K         0.641   0.683   0.566   0.210   0.270   0.103   0.557   0.628   0.423
250   Q         0.641   0.631   0.572   0.797   0.783   0.692   0.557   0.541   0.433
251   F         1.963   1.972   2.015   2.310   2.325   2.392   2.170   2.182   2.248
252   N         1.963   1.972   2.015   1.928   1.934   2.007   2.170   2.182   2.248
253   E        -1.297  -1.295  -1.265  -1.426  -1.390  -1.375  -1.055  -1.050  -1.000
254   K         0.641   0.683   0.566   0.181   0.243   0.066   0.557   0.628   0.423
255   L         1.963   1.972   2.015   2.030   2.045   2.110   2.170   2.182   2.248
256   S        -0.482  -0.429  -0.490  -0.524  -0.440  -0.541  -0.518  -0.446  -0.519
257   R        -0.482  -0.466  -0.493  -0.403  -0.369  -0.428  -0.518  -0.494  -0.522
258   E        -0.482  -0.494  -0.510  -0.531  -0.545  -0.571  -0.518  -0.533  -0.545
259   S        -1.297  -1.295  -1.265  -0.698  -0.681  -0.640  -1.055  -1.050  -1.000
260   K        -0.621  -0.620  -0.584  -1.110  -1.101  -1.056  -0.697  -0.694  -0.640
261   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
262   S         0.466   0.480   0.463   0.281   0.306   0.267   0.259   0.283   0.242
263   E        -0.482  -0.493  -0.506  -0.985  -0.998  -1.015  -0.518  -0.531  -0.539
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P53277
Output conservation file - output/P53277
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
