1     M         2.057   2.066   2.132   2.338   2.353   2.460   2.337   2.351   2.462
2     S         0.926   0.924   0.796   0.688   0.684   0.507   0.932   0.928   0.691
3     E        -0.327  -0.317  -0.318  -0.541  -0.533  -0.506  -0.474  -0.460  -0.446
4     D        -0.327  -0.338  -0.322  -0.646  -0.670  -0.637  -0.474  -0.483  -0.450
5     K        -0.327  -0.303  -0.293  -0.333  -0.301  -0.272  -0.474  -0.444  -0.417
6     A        -0.953  -0.967  -0.938  -0.972  -0.994  -0.945  -0.825  -0.837  -0.788
7     K        -0.953  -0.977  -0.971  -0.739  -0.770  -0.757  -0.825  -0.848  -0.824
8     L        -0.953  -0.939  -0.974  -0.835  -0.813  -0.883  -0.825  -0.806  -0.827
9     G        -0.426  -0.421  -0.367  -0.346  -0.334  -0.252  -0.591  -0.583  -0.506
10    T        -0.426  -0.421  -0.367  -0.466  -0.465  -0.374  -0.591  -0.583  -0.506
11    T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    R         0.619   0.597   0.613   0.476   0.438   0.455   0.385   0.342   0.348
13    S         0.619   0.597   0.613   0.113   0.072   0.091   0.385   0.342   0.348
14    A        -0.327  -0.327  -0.306  -0.308  -0.311  -0.267  -0.474  -0.470  -0.430
15    T        -0.090  -0.104  -0.219   0.050   0.027  -0.177  -0.122  -0.140  -0.300
16    E         0.536   0.535   0.578   0.355   0.352   0.406   0.229   0.225   0.281
17    Y        -0.090  -0.104  -0.219   0.207   0.186  -0.050  -0.122  -0.140  -0.300
18    R        -0.090  -0.061  -0.167  -0.045   0.001  -0.152  -0.122  -0.079  -0.227
19    L        -0.090  -0.104  -0.219  -0.135  -0.156  -0.347  -0.122  -0.140  -0.300
20    S        -0.090  -0.104  -0.219  -0.282  -0.300  -0.449  -0.122  -0.140  -0.300
21    I        -1.580  -1.579  -1.529  -1.429  -1.439  -1.347  -1.176  -1.171  -1.100
22    G         0.926   0.946   0.803   0.699   0.725   0.534   0.932   0.964   0.703
23    S         0.536   0.535   0.578   0.143   0.143   0.217   0.229   0.225   0.281
24    A        -0.327  -0.317  -0.318  -0.524  -0.510  -0.493  -0.474  -0.460  -0.446
25    P        -0.327  -0.338  -0.322  -0.449  -0.465  -0.425  -0.474  -0.483  -0.450
26    T        -1.580  -1.579  -1.529  -1.303  -1.310  -1.220  -1.176  -1.171  -1.100
27    S         0.926   0.924   0.796   0.631   0.626   0.422   0.932   0.928   0.691
28    R         0.536   0.535   0.578   0.432   0.432   0.506   0.229   0.225   0.281
29    R         2.057   2.066   2.132   1.989   2.003   2.108   2.337   2.351   2.462
30    S         2.057   2.066   2.132   1.741   1.753   1.857   2.337   2.351   2.462
31    S         2.057   2.066   2.132   1.741   1.753   1.857   2.337   2.351   2.462
32    M        -0.327  -0.338  -0.322  -0.187  -0.205  -0.187  -0.474  -0.483  -0.450
33    G         0.619   0.585   0.622   0.659   0.597   0.650   0.385   0.320   0.366
34    E        -1.076  -1.072  -1.022  -0.864  -0.869  -0.776  -0.957  -0.949  -0.877
35    S        -0.293  -0.289  -0.273  -0.491  -0.499  -0.473  -0.408  -0.401  -0.377
36    S        -1.076  -1.072  -1.022  -1.209  -1.214  -1.125  -0.957  -0.949  -0.877
37    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
38    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
39    S        -0.426  -0.414  -0.367  -0.534  -0.561  -0.442  -0.591  -0.574  -0.506
40    L         0.619   0.568   0.610   0.140   0.038   0.110   0.385   0.287   0.342
41    M         0.619   0.568   0.610   0.584   0.526   0.578   0.385   0.287   0.342
42    K         2.057   2.066   2.132   2.115   2.120   2.235   2.337   2.351   2.462
43    F        -0.426  -0.414  -0.367  -0.236  -0.213  -0.141  -0.591  -0.574  -0.506
44    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
45    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
46    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
47    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
48    A        -0.953  -0.977  -0.971  -0.725  -0.764  -0.752  -0.825  -0.848  -0.824
49    D         2.057   2.066   2.132   2.181   2.197   2.302   2.337   2.351   2.462
50    Q        -0.327  -0.328  -0.305  -0.243  -0.244  -0.204  -0.474  -0.472  -0.429
51    E        -0.090  -0.117  -0.179   0.156   0.123   0.039  -0.122  -0.158  -0.243
52    G        -0.953  -0.939  -0.974  -1.013  -0.978  -1.049  -0.825  -0.806  -0.827
53    L         0.786   0.789   0.740   0.780   0.784   0.719   0.690   0.693   0.589
54    T        -0.293  -0.304  -0.314  -0.338  -0.352  -0.382  -0.408  -0.422  -0.433
55    S        -1.076  -1.074  -1.022  -1.147  -1.151  -1.062  -0.957  -0.952  -0.877
56    S        -0.293  -0.292  -0.279  -0.403  -0.409  -0.402  -0.408  -0.406  -0.384
57    V        -1.076  -1.074  -1.022  -1.153  -1.147  -1.068  -0.957  -0.952  -0.877
58    G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
59    E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
60    Y        -0.426  -0.421  -0.367  -0.678  -0.690  -0.588  -0.591  -0.583  -0.506
61    N         0.619   0.638   0.622   0.431   0.468   0.427   0.385   0.420   0.366
62    E        -0.426  -0.421  -0.367  -0.516  -0.499  -0.424  -0.591  -0.583  -0.506
63    N        -0.426  -0.421  -0.367  -0.537  -0.523  -0.445  -0.591  -0.583  -0.506
64    T        -0.426  -0.421  -0.367  -0.260  -0.248  -0.166  -0.591  -0.583  -0.506
65    I         0.619   0.638   0.622   0.581   0.618   0.557   0.385   0.420   0.366
66    Q        -0.426  -0.421  -0.367  -0.495  -0.487  -0.403  -0.591  -0.583  -0.506
67    Q        -0.953  -0.939  -0.974  -0.781  -0.760  -0.804  -0.825  -0.806  -0.827
68    L        -0.953  -0.956  -0.963  -0.605  -0.606  -0.637  -0.825  -0.825  -0.815
69    L        -0.953  -0.977  -0.971  -0.894  -0.922  -0.903  -0.825  -0.848  -0.824
70    L        -0.090  -0.104  -0.219  -0.028  -0.046  -0.202  -0.122  -0.140  -0.300
71    P         0.536   0.535   0.578   0.402   0.397   0.461   0.229   0.225   0.281
72    K         0.536   0.544   0.590   0.483   0.499   0.567   0.229   0.242   0.303
73    I        -0.327  -0.338  -0.322  -0.204  -0.218  -0.204  -0.474  -0.483  -0.450
74    R        -1.580  -1.579  -1.529  -1.342  -1.331  -1.259  -1.176  -1.171  -1.100
75    E        -0.953  -0.942  -0.962  -1.003  -0.988  -1.045  -0.825  -0.809  -0.814
76    L         2.057   2.066   2.132   1.980   1.993   2.099   2.337   2.351   2.462
77    S        -0.090  -0.065  -0.161  -0.282  -0.247  -0.371  -0.122  -0.085  -0.218
78    D         0.926   0.919   0.808   1.111   1.104   0.936   0.932   0.919   0.713
79    S         0.926   0.924   0.796   0.688   0.684   0.507   0.932   0.928   0.691
80    I        -0.953  -0.928  -0.939  -0.613  -0.572  -0.593  -0.825  -0.793  -0.789
81    I        -0.327  -0.317  -0.318  -0.211  -0.196  -0.182  -0.474  -0.460  -0.446
82    T         0.926   0.924   0.796   1.115   1.112   0.920   0.932   0.928   0.691
83    L         2.057   2.066   2.132   1.980   1.993   2.099   2.337   2.351   2.462
84    D         2.057   2.066   2.132   2.181   2.197   2.302   2.337   2.351   2.462
85    S        -0.953  -0.977  -0.971  -1.098  -1.123  -1.088  -0.825  -0.848  -0.824
86    N         0.926   0.919   0.808   0.991   0.985   0.844   0.932   0.919   0.713
87    F         0.926   0.946   0.803   1.307   1.337   1.140   0.932   0.964   0.703
88    T         0.926   0.919   0.808   1.169   1.160   1.018   0.932   0.919   0.713
89    R        -0.953  -0.977  -0.971  -0.863  -0.889  -0.870  -0.825  -0.848  -0.824
90    L         0.926   0.902   0.813   0.962   0.931   0.820   0.932   0.891   0.722
91    N        -0.090  -0.104  -0.219   0.070   0.056  -0.080  -0.122  -0.140  -0.300
92    F        -0.090  -0.104  -0.219   0.260   0.242   0.052  -0.122  -0.140  -0.300
93    I         2.057   2.066   2.132   2.223   2.237   2.344   2.337   2.351   2.462
94    H         2.057   2.066   2.132   2.366   2.380   2.489   2.337   2.351   2.462
95    E         0.536   0.549   0.579   0.457   0.482   0.519   0.229   0.252   0.282
96    S        -0.953  -0.942  -0.962  -1.064  -1.042  -1.042  -0.825  -0.809  -0.814
97    L         0.536   0.558   0.588   0.409   0.454   0.481   0.229   0.269   0.300
98    A        -0.327  -0.303  -0.318  -0.529  -0.502  -0.482  -0.474  -0.444  -0.445
99    D         0.926   0.919   0.808   1.075   1.068   0.885   0.932   0.919   0.713
100   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
101   L         0.536   0.535   0.578   0.401   0.400   0.473   0.229   0.225   0.281
102   N         2.057   2.066   2.132   2.002   2.018   2.121   2.337   2.351   2.462
103   E         2.057   2.066   2.132   2.147   2.162   2.268   2.337   2.351   2.462
104   S         0.926   0.902   0.813   0.688   0.654   0.533   0.932   0.891   0.722
105   L         0.536   0.536   0.585   0.499   0.495   0.562   0.229   0.227   0.294
106   G        -0.327  -0.338  -0.322  -0.367  -0.391  -0.387  -0.474  -0.483  -0.450
107   S         0.926   0.902   0.813   0.688   0.654   0.533   0.932   0.891   0.722
108   L         0.536   0.535   0.578   0.401   0.400   0.473   0.229   0.225   0.281
109   L         2.057   2.066   2.132   1.980   1.993   2.099   2.337   2.351   2.462
110   Y         2.057   2.066   2.132   2.403   2.418   2.526   2.337   2.351   2.462
111   G         2.057   2.066   2.132   2.235   2.250   2.357   2.337   2.351   2.462
112   I         0.926   0.946   0.803   0.932   0.959   0.762   0.932   0.964   0.703
113   M         0.536   0.535   0.578   0.380   0.370   0.412   0.229   0.225   0.281
114   S        -0.953  -0.956  -0.963  -0.581  -0.579  -0.618  -0.825  -0.825  -0.815
115   N         0.536   0.535   0.578   0.336   0.335   0.400   0.229   0.225   0.281
116   S         0.536   0.535   0.578   0.207   0.208   0.286   0.229   0.225   0.281
117   W         2.057   2.066   2.132   2.467   2.482   2.591   2.337   2.351   2.462
118   C         2.057   2.066   2.132   2.455   2.470   2.579   2.337   2.351   2.462
119   V         2.057   2.066   2.132   2.272   2.288   2.394   2.337   2.351   2.462
120   E         0.536   0.558   0.588   0.467   0.510   0.544   0.229   0.269   0.300
121   F         2.057   2.066   2.132   2.326   2.342   2.448   2.337   2.351   2.462
122   S         0.926   0.946   0.803   0.938   0.966   0.710   0.932   0.964   0.703
123   Q        -0.327  -0.317  -0.318  -0.330  -0.313  -0.303  -0.474  -0.460  -0.446
124   A        -0.327  -0.338  -0.322  -0.055  -0.063  -0.037  -0.474  -0.483  -0.450
125   P         0.926   0.902   0.813   0.938   0.896   0.730   0.932   0.891   0.722
126   H        -0.327  -0.303  -0.318  -0.431  -0.401  -0.391  -0.474  -0.444  -0.445
127   D         0.536   0.536   0.585   0.322   0.323   0.397   0.229   0.227   0.294
128   I        -1.580  -1.579  -1.529  -1.253  -1.254  -1.170  -1.176  -1.171  -1.100
129   Q        -0.090  -0.078  -0.168   0.160   0.178   0.036  -0.122  -0.104  -0.228
130   D        -0.953  -0.939  -0.974  -0.434  -0.401  -0.474  -0.825  -0.806  -0.827
131   D         0.926   0.946   0.803   1.086   1.116   0.907   0.932   0.964   0.703
132   L        -0.953  -0.942  -0.962  -0.870  -0.854  -0.866  -0.825  -0.809  -0.814
133   I        -0.953  -0.939  -0.974  -0.957  -0.931  -0.980  -0.825  -0.806  -0.827
134   A        -0.953  -0.956  -0.963  -0.870  -0.873  -0.867  -0.825  -0.825  -0.815
135   I        -0.953  -0.942  -0.962  -0.869  -0.858  -0.905  -0.825  -0.809  -0.814
136   K        -0.953  -0.950  -0.934  -0.758  -0.741  -0.723  -0.825  -0.818  -0.784
137   Q        -0.426  -0.421  -0.367  -0.495  -0.492  -0.403  -0.591  -0.583  -0.506
138   L         0.619   0.638   0.622   0.470   0.499   0.473   0.385   0.420   0.366
139   K        -0.090  -0.087  -0.170   0.025   0.032  -0.112  -0.122  -0.116  -0.232
140   S        -0.090  -0.083  -0.183  -0.019  -0.003  -0.190  -0.122  -0.110  -0.249
141   L         0.926   0.919   0.808   0.873   0.862   0.684   0.932   0.919   0.713
142   E        -0.953  -0.928  -0.939  -0.939  -0.881  -0.927  -0.825  -0.793  -0.789
143   D        -0.953  -0.953  -0.934  -0.699  -0.694  -0.663  -0.825  -0.821  -0.784
144   E         0.536   0.535   0.578   0.348   0.344   0.398   0.229   0.225   0.281
145   K        -0.327  -0.338  -0.322  -0.332  -0.344  -0.330  -0.474  -0.483  -0.450
146   N        -1.580  -1.579  -1.529  -1.660  -1.638  -1.581  -1.176  -1.171  -1.100
147   N        -1.580  -1.579  -1.529  -1.318  -1.306  -1.235  -1.176  -1.171  -1.100
148   L         2.057   2.066   2.132   1.980   1.993   2.099   2.337   2.351   2.462
149   V        -0.953  -0.964  -0.942  -0.682  -0.693  -0.652  -0.825  -0.834  -0.792
150   M        -1.580  -1.579  -1.529  -1.411  -1.393  -1.329  -1.176  -1.171  -1.100
151   E        -0.327  -0.317  -0.296  -0.442  -0.421  -0.386  -0.474  -0.459  -0.420
152   L         0.926   0.924   0.796   0.932   0.930   0.751   0.932   0.928   0.691
153   S        -1.076  -1.074  -1.022  -1.322  -1.325  -1.239  -0.957  -0.952  -0.877
154   N        -1.076  -1.074  -1.022  -1.354  -1.356  -1.272  -0.957  -0.952  -0.877
155   M        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
156   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
157   R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
158   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
159   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
160   K        -1.076  -1.074  -1.022  -0.919  -0.918  -0.832  -0.957  -0.952  -0.877
161   R        -0.293  -0.286  -0.271  -0.357  -0.345  -0.319  -0.408  -0.397  -0.373
162   K         0.926   0.924   0.796   1.069   1.072   0.876   0.932   0.928   0.691
163   K        -0.953  -0.956  -0.963  -0.888  -0.893  -0.908  -0.825  -0.825  -0.815
164   D        -0.090  -0.100  -0.179  -0.052  -0.062  -0.182  -0.122  -0.135  -0.243
165   E        -0.090  -0.065  -0.161   0.102   0.142  -0.001  -0.122  -0.085  -0.218
166   Q        -0.327  -0.338  -0.322  -0.428  -0.451  -0.424  -0.474  -0.483  -0.450
167   G        -0.327  -0.317  -0.318  -0.382  -0.372  -0.347  -0.474  -0.460  -0.446
168   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
169   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
170   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
171   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
172   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
173   K         2.057   2.066   2.132   2.139   2.156   2.259   2.337   2.351   2.462
174   A        -1.580  -1.579  -1.529  -1.318  -1.321  -1.235  -1.176  -1.171  -1.100
175   S        -0.327  -0.303  -0.318  -0.738  -0.706  -0.713  -0.474  -0.444  -0.445
176   Q        -0.953  -0.939  -0.974  -0.851  -0.829  -0.858  -0.825  -0.806  -0.827
177   N        -1.580  -1.579  -1.529  -1.713  -1.718  -1.634  -1.176  -1.171  -1.100
178   K        -0.953  -0.967  -0.938  -1.129  -1.143  -1.090  -0.825  -0.837  -0.788
179   Q        -1.580  -1.579  -1.529  -1.394  -1.398  -1.312  -1.176  -1.171  -1.100
180   F        -1.580  -1.579  -1.529  -1.310  -1.318  -1.227  -1.176  -1.171  -1.100
181   N        -1.580  -1.579  -1.529  -1.640  -1.620  -1.561  -1.176  -1.171  -1.100
182   Q         0.926   0.924   0.796   1.168   1.166   0.972   0.932   0.928   0.691
183   P         2.057   2.066   2.132   2.215   2.228   2.337   2.337   2.351   2.462
184   L         0.619   0.638   0.622   0.470   0.499   0.473   0.385   0.420   0.366
185   F         0.619   0.597   0.613   0.578   0.523   0.502   0.385   0.342   0.348
186   P        -1.580  -1.579  -1.529  -1.601  -1.607  -1.521  -1.176  -1.171  -1.100
187   S        -1.580  -1.579  -1.529  -1.495  -1.484  -1.414  -1.176  -1.171  -1.100
188   S        -0.953  -0.942  -0.962  -1.098  -1.082  -1.080  -0.825  -0.809  -0.814
189   Q        -0.090  -0.061  -0.167   0.119   0.169  -0.014  -0.122  -0.079  -0.227
190   V        -0.090  -0.121  -0.174   0.202   0.159   0.070  -0.122  -0.164  -0.237
191   R        -0.293  -0.274  -0.310  -0.373  -0.342  -0.394  -0.408  -0.380  -0.429
192   K        -1.076  -1.074  -1.022  -1.401  -1.395  -1.319  -0.957  -0.952  -0.877
193   Y        -1.076  -1.074  -1.022  -0.715  -0.706  -0.625  -0.957  -0.952  -0.877
194   R         0.619   0.565   0.613   0.287   0.166   0.229   0.385   0.282   0.348
195   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
196   S         0.619   0.663   0.650   0.169   0.254   0.207   0.385   0.465   0.420
197   Y        -1.076  -1.060  -1.022  -0.785  -0.749  -0.697  -0.957  -0.937  -0.877
198   D        -1.076  -1.060  -1.022  -0.929  -0.900  -0.842  -0.957  -0.937  -0.877
199   N         0.786   0.803   0.735   0.677   0.707   0.580   0.690   0.719   0.579
200   R        -0.327  -0.331  -0.301  -0.378  -0.379  -0.331  -0.474  -0.475  -0.425
201   D        -0.953  -0.956  -0.963  -0.835  -0.837  -0.855  -0.825  -0.825  -0.815
202   K        -0.327  -0.317  -0.318  -0.460  -0.444  -0.437  -0.474  -0.460  -0.446
203   R        -1.580  -1.579  -1.529  -1.361  -1.346  -1.279  -1.176  -1.171  -1.100
204   K        -0.090  -0.100  -0.179   0.265   0.250   0.115  -0.122  -0.135  -0.243
205   P        -1.076  -1.060  -1.022  -1.044  -1.041  -0.958  -0.957  -0.937  -0.877
206   S        -0.293  -0.311  -0.300  -0.379  -0.385  -0.351  -0.408  -0.437  -0.415
207   K        -1.076  -1.060  -1.022  -1.129  -1.109  -1.044  -0.957  -0.937  -0.877
208   I        -1.076  -1.060  -1.022  -0.934  -0.893  -0.847  -0.957  -0.937  -0.877
209   G        -0.293  -0.236  -0.271  -0.357  -0.251  -0.341  -0.408  -0.328  -0.373
210   N        -0.293  -0.345  -0.310  -0.541  -0.614  -0.597  -0.408  -0.480  -0.429
211   N        -0.327  -0.303  -0.318  -0.378  -0.342  -0.361  -0.474  -0.444  -0.445
212   L        -0.090  -0.100  -0.179   0.025   0.012  -0.114  -0.122  -0.135  -0.243
213   Q        -0.953  -0.939  -0.974  -0.720  -0.703  -0.750  -0.825  -0.806  -0.827
214   V        -0.953  -0.939  -0.974  -0.720  -0.705  -0.710  -0.825  -0.806  -0.827
215   E        -0.327  -0.317  -0.318  -0.237  -0.219  -0.216  -0.474  -0.460  -0.446
216   N        -0.953  -0.928  -0.939  -0.714  -0.668  -0.691  -0.825  -0.793  -0.789
217   E        -0.953  -0.964  -0.942  -0.834  -0.847  -0.817  -0.825  -0.834  -0.792
218   E        -0.293  -0.286  -0.271  -0.296  -0.284  -0.265  -0.408  -0.397  -0.373
219   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
220   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
221   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
222   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
223   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
224   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
225   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
226   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
227   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
228   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
229   D        -1.076  -1.074  -1.022  -1.138  -1.133  -1.053  -0.957  -0.952  -0.877
230   Y        -1.076  -1.074  -1.022  -0.981  -0.970  -0.894  -0.957  -0.952  -0.877
231   E         0.926   0.946   0.803   1.111   1.142   0.927   0.932   0.964   0.703
232   D        -0.953  -0.942  -0.962  -0.901  -0.882  -0.934  -0.825  -0.809  -0.814
233   D        -0.953  -0.977  -0.971  -0.621  -0.651  -0.630  -0.825  -0.848  -0.824
234   T        -0.953  -0.977  -0.971  -0.818  -0.857  -0.857  -0.825  -0.848  -0.824
235   S        -0.327  -0.317  -0.318  -0.543  -0.523  -0.556  -0.474  -0.460  -0.446
236   S        -0.327  -0.338  -0.322  -0.709  -0.713  -0.681  -0.474  -0.483  -0.450
237   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
238   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
239   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
240   E        -0.090  -0.121  -0.174  -0.033  -0.082  -0.191  -0.122  -0.164  -0.237
241   A         0.536   0.535   0.578   0.527   0.524   0.589   0.229   0.225   0.281
242   S         0.926   0.919   0.808   0.684   0.675   0.520   0.932   0.919   0.713
243   F         2.057   2.066   2.132   2.326   2.342   2.448   2.337   2.351   2.462
244   V         0.926   0.919   0.808   1.166   1.158   0.974   0.932   0.919   0.713
245   L        -0.953  -0.956  -0.963  -1.121  -1.122  -1.107  -0.825  -0.825  -0.815
246   N         2.057   2.066   2.132   2.002   2.018   2.121   2.337   2.351   2.462
247   P         2.057   2.066   2.132   2.115   2.108   2.235   2.337   2.351   2.462
248   T        -0.293  -0.311  -0.300  -0.382  -0.453  -0.423  -0.408  -0.437  -0.415
249   N        -0.293  -0.345  -0.310  -0.355  -0.433  -0.378  -0.408  -0.480  -0.429
250   I        -0.426  -0.414  -0.367  -0.580  -0.530  -0.489  -0.591  -0.574  -0.506
251   G        -0.426  -0.414  -0.367  -0.763  -0.711  -0.674  -0.591  -0.574  -0.506
252   M        -0.426  -0.414  -0.367  -0.211  -0.184  -0.116  -0.591  -0.574  -0.506
253   S        -0.090  -0.117  -0.179  -0.236  -0.269  -0.337  -0.122  -0.158  -0.243
254   K         0.536   0.535   0.578   0.341   0.338   0.391   0.229   0.225   0.281
255   S        -0.953  -0.939  -0.974  -0.885  -0.859  -0.949  -0.825  -0.806  -0.827
256   S        -0.953  -0.939  -0.974  -0.860  -0.839  -0.894  -0.825  -0.806  -0.827
257   Q         0.926   0.902   0.813   1.214   1.183   1.067   0.932   0.891   0.722
258   G        -0.953  -0.939  -0.974  -0.816  -0.790  -0.844  -0.825  -0.806  -0.827
259   H        -0.953  -0.928  -0.939  -0.886  -0.862  -0.831  -0.825  -0.793  -0.789
260   V        -1.580  -1.579  -1.529  -1.532  -1.542  -1.451  -1.176  -1.171  -1.100
261   T        -0.953  -0.953  -0.934  -0.921  -0.916  -0.902  -0.825  -0.821  -0.784
262   K        -0.953  -0.956  -0.963  -0.752  -0.754  -0.776  -0.825  -0.825  -0.815
263   T        -1.076  -1.060  -1.022  -1.176  -1.143  -1.092  -0.957  -0.937  -0.877
264   T        -0.293  -0.323  -0.301  -0.637  -0.688  -0.645  -0.408  -0.452  -0.416
265   R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
266   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
267   N         0.491   0.505   0.560   0.252   0.287   0.369   0.141   0.167   0.245
268   N        -0.293  -0.345  -0.310  -0.362  -0.434  -0.385  -0.408  -0.480  -0.429
269   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
270   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
271   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
272   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
273   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
274   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
275   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
276   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
277   N        -1.076  -1.060  -1.022  -1.273  -1.244  -1.189  -0.957  -0.937  -0.877
278   T        -0.293  -0.250  -0.275  -0.255  -0.207  -0.227  -0.408  -0.347  -0.379
279   N        -1.076  -1.060  -1.022  -1.291  -1.260  -1.208  -0.957  -0.937  -0.877
280   S         0.786   0.684   0.697   0.489   0.328   0.344   0.690   0.504   0.508
281   K        -0.293  -0.311  -0.300  -0.322  -0.362  -0.352  -0.408  -0.437  -0.415
282   L         0.926   0.924   0.796   0.902   0.898   0.707   0.932   0.928   0.691
283   R         0.536   0.535   0.578   0.278   0.273   0.338   0.229   0.225   0.281
284   R        -0.090  -0.104  -0.219  -0.187  -0.211  -0.422  -0.122  -0.140  -0.300
285   K        -0.953  -0.977  -0.971  -1.007  -1.049  -1.067  -0.825  -0.848  -0.824
286   S        -0.090  -0.104  -0.219  -0.353  -0.374  -0.545  -0.122  -0.140  -0.300
287   I        -0.090  -0.104  -0.219   0.082   0.061  -0.149  -0.122  -0.140  -0.300
288   L        -0.090  -0.104  -0.219   0.011  -0.006  -0.150  -0.122  -0.140  -0.300
289   H         0.926   0.919   0.808   1.303   1.294   1.130   0.932   0.919   0.713
290   T        -0.953  -0.977  -0.971  -0.892  -0.934  -0.943  -0.825  -0.848  -0.824
291   I         0.536   0.535   0.578   0.276   0.266   0.311   0.229   0.225   0.281
292   R        -0.090  -0.104  -0.219   0.009  -0.007  -0.157  -0.122  -0.140  -0.300
293   N        -0.090  -0.104  -0.219  -0.243  -0.266  -0.504  -0.122  -0.140  -0.300
294   S        -0.327  -0.338  -0.322  -0.599  -0.602  -0.594  -0.474  -0.483  -0.450
295   I        -0.327  -0.338  -0.322  -0.285  -0.302  -0.263  -0.474  -0.483  -0.450
296   A         0.536   0.535   0.578   0.396   0.390   0.445   0.229   0.225   0.281
297   -         0.619   0.568   0.610   0.480   0.396   0.467   0.385   0.288   0.342
298   -         0.619   0.568   0.610   0.530   0.447   0.512   0.385   0.288   0.342
299   -         0.619   0.568   0.610   0.650   0.554   0.616   0.385   0.288   0.342
300   -         0.619   0.568   0.610   0.459   0.390   0.447   0.385   0.288   0.342
301   -         2.057   2.066   2.132   1.951   1.975   2.069   2.337   2.351   2.462
302   -         0.619   0.568   0.610   0.391   0.302   0.354   0.385   0.288   0.342
303   -         0.619   0.568   0.610   0.816   0.716   0.775   0.385   0.288   0.342
304   -         0.619   0.568   0.610   0.690   0.577   0.633   0.385   0.288   0.342
305   S        -0.327  -0.338  -0.322  -0.719  -0.725  -0.691  -0.474  -0.483  -0.450
306   G         0.926   0.974   0.817   1.173   1.241   1.015   0.932   1.010   0.728
307   A        -0.426  -0.421  -0.367  -0.678  -0.663  -0.588  -0.591  -0.583  -0.506
308   D         0.619   0.597   0.613   0.615   0.578   0.593   0.385   0.342   0.348
309   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
310   L        -0.426  -0.421  -0.367  -0.358  -0.348  -0.264  -0.591  -0.583  -0.506
311   P        -0.426  -0.421  -0.367  -0.438  -0.430  -0.345  -0.591  -0.583  -0.506
312   I         0.619   0.640   0.622   0.507   0.541   0.508   0.385   0.423   0.365
313   E         0.619   0.640   0.622   0.560   0.602   0.549   0.385   0.423   0.365
314   N        -0.426  -0.421  -0.367  -0.661  -0.650  -0.571  -0.591  -0.583  -0.506
315   D        -0.426  -0.421  -0.367  -0.665  -0.675  -0.575  -0.591  -0.583  -0.506
316   N        -0.426  -0.421  -0.367  -0.604  -0.602  -0.514  -0.591  -0.583  -0.506
317   V        -0.426  -0.421  -0.367  -0.334  -0.329  -0.240  -0.591  -0.583  -0.506
318   V         0.619   0.638   0.622   0.726   0.761   0.721   0.385   0.420   0.366
319   N        -0.426  -0.421  -0.367  -0.776  -0.784  -0.688  -0.591  -0.583  -0.506
320   L        -0.426  -0.421  -0.367  -0.438  -0.431  -0.345  -0.591  -0.583  -0.506
321   G         0.619   0.597   0.613   0.661   0.621   0.629   0.385   0.342   0.348
322   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
323   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
324   H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
325   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
326   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
327   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
328   R         2.057   2.066   2.132   2.020   2.033   2.139   2.337   2.351   2.462
329   I         0.619   0.638   0.622   0.708   0.742   0.707   0.385   0.420   0.366
330   S         0.619   0.597   0.613   0.212   0.178   0.211   0.385   0.342   0.348
331   L         0.619   0.597   0.613   0.470   0.432   0.457   0.385   0.342   0.348
332   G         0.619   0.597   0.613   0.594   0.547   0.548   0.385   0.342   0.348
333   S        -0.426  -0.421  -0.367  -0.669  -0.656  -0.579  -0.591  -0.583  -0.506
334   G         2.057   2.066   2.132   2.235   2.250   2.357   2.337   2.351   2.462
335   A         0.619   0.597   0.613   0.409   0.351   0.338   0.385   0.342   0.348
336   A         0.619   0.597   0.613   0.409   0.351   0.338   0.385   0.342   0.348
337   R         0.619   0.597   0.613   0.492   0.453   0.475   0.385   0.342   0.348
338   V        -0.327  -0.338  -0.322  -0.338  -0.357  -0.315  -0.474  -0.483  -0.450
339   V        -0.327  -0.338  -0.322  -0.100  -0.110  -0.083  -0.474  -0.483  -0.450
340   N        -0.953  -0.939  -0.974  -0.941  -0.899  -1.005  -0.825  -0.806  -0.827
341   G         0.536   0.531   0.571   0.288   0.265   0.298   0.229   0.216   0.267
342   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
343   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
344   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
345   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
346   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
347   R        -0.293  -0.274  -0.310  -0.430  -0.400  -0.462  -0.408  -0.380  -0.429
348   N         2.057   2.066   2.132   1.991   2.004   2.110   2.337   2.351   2.462
349   S        -1.076  -1.074  -1.022  -1.132  -1.132  -1.047  -0.957  -0.952  -0.877
350   M        -1.076  -1.074  -1.022  -0.897  -0.885  -0.810  -0.957  -0.952  -0.877
351   F        -1.076  -1.074  -1.022  -0.950  -0.942  -0.863  -0.957  -0.952  -0.877
352   S        -0.953  -0.939  -0.974  -0.855  -0.831  -0.905  -0.825  -0.806  -0.827
353   G        -0.953  -0.928  -0.939  -1.058  -1.031  -1.015  -0.825  -0.793  -0.789
354   R        -0.327  -0.329  -0.304  -0.792  -0.802  -0.765  -0.474  -0.473  -0.428
355   A        -0.953  -0.942  -0.962  -0.682  -0.662  -0.688  -0.825  -0.809  -0.814
356   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
357   R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
358   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
359   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
360   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
361   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
362   S        -0.090  -0.061  -0.167  -0.348  -0.307  -0.461  -0.122  -0.079  -0.227
363   R         0.926   0.902   0.813   0.931   0.899   0.772   0.932   0.891   0.722
364   H        -0.953  -0.977  -0.971  -0.787  -0.835  -0.858  -0.825  -0.848  -0.824
365   S        -0.327  -0.338  -0.322  -0.604  -0.604  -0.579  -0.474  -0.483  -0.450
366   V        -1.580  -1.579  -1.529  -1.329  -1.326  -1.246  -1.176  -1.171  -1.100
367   A        -0.953  -0.928  -0.939  -0.730  -0.694  -0.698  -0.825  -0.793  -0.789
368   K        -0.953  -0.931  -0.936  -0.682  -0.645  -0.650  -0.825  -0.796  -0.786
369   K        -1.580  -1.579  -1.529  -1.337  -1.336  -1.255  -1.176  -1.171  -1.100
370   T        -0.090  -0.087  -0.170   0.003   0.006  -0.127  -0.122  -0.116  -0.232
371   E        -0.090  -0.087  -0.170  -0.111  -0.104  -0.243  -0.122  -0.116  -0.232
372   K        -0.090  -0.087  -0.170  -0.206  -0.202  -0.357  -0.122  -0.116  -0.232
373   K        -0.090  -0.083  -0.183   0.214   0.229   0.069  -0.122  -0.110  -0.249
374   I        -0.953  -0.956  -0.963  -0.670  -0.673  -0.689  -0.825  -0.825  -0.815
375   N        -0.327  -0.338  -0.294  -0.490  -0.504  -0.439  -0.474  -0.484  -0.417
376   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
377   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
378   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
379   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
380   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
381   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
382   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
383   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
384   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
385   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
386   -         0.619   0.661   0.645   0.449   0.509   0.487   0.385   0.462   0.410
387   -        -0.426  -0.415  -0.367  -0.401  -0.389  -0.308  -0.591  -0.574  -0.506
388   T        -1.580  -1.579  -1.529  -1.551  -1.556  -1.470  -1.176  -1.171  -1.100
389   R         2.057   2.066   2.132   1.989   2.003   2.108   2.337   2.351   2.462
390   P         2.057   2.066   2.132   2.105   2.116   2.225   2.337   2.351   2.462
391   P         2.057   2.066   2.132   2.105   2.116   2.225   2.337   2.351   2.462
392   F         2.057   2.066   2.132   2.326   2.342   2.448   2.337   2.351   2.462
393   R         0.926   0.974   0.817   0.920   0.988   0.761   0.932   1.010   0.728
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P53267
Output conservation file - output/P53267
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
