1     M         2.210   2.226   2.270   2.582   2.606   2.678   2.449   2.473   2.539
2     V        -1.275  -1.265  -1.239  -0.991  -0.953  -0.930  -1.024  -1.009  -0.965
3     F        -1.275  -1.265  -1.239  -0.907  -0.903  -0.845  -1.024  -1.009  -0.965
4     G        -1.275  -1.265  -1.239  -1.192  -1.180  -1.133  -1.024  -1.009  -0.965
5     Q        -0.404  -0.425  -0.427  -0.202  -0.242  -0.268  -0.445  -0.471  -0.467
6     L         0.796   0.829   0.735   0.498   0.553   0.407   0.712   0.766   0.597
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     Y        -0.404  -0.362  -0.400  -0.563  -0.512  -0.542  -0.445  -0.387  -0.432
9     A        -1.275  -1.265  -1.239  -1.312  -1.299  -1.254  -1.024  -1.009  -0.965
10    L        -1.275  -1.265  -1.239  -1.362  -1.322  -1.304  -1.024  -1.009  -0.965
11    F        -0.404  -0.446  -0.437  -0.590  -0.684  -0.701  -0.445  -0.499  -0.481
12    I        -1.275  -1.265  -1.239  -1.174  -1.130  -1.115  -1.024  -1.009  -0.965
13    F        -1.275  -1.265  -1.239  -1.109  -1.104  -1.049  -1.024  -1.009  -0.965
14    T        -0.404  -0.337  -0.403  -0.681  -0.589  -0.672  -0.445  -0.354  -0.436
15    L         0.467   0.477   0.516   0.058   0.074   0.125   0.134   0.148   0.203
16    S        -0.404  -0.425  -0.427  -0.409  -0.436  -0.418  -0.445  -0.471  -0.467
17    C        -1.275  -1.265  -1.239  -0.595  -0.591  -0.531  -1.024  -1.009  -0.965
18    C        -0.404  -0.362  -0.400  -0.090  -0.041  -0.073  -0.445  -0.387  -0.432
19    I        -0.404  -0.362  -0.400  -0.703  -0.639  -0.692  -0.445  -0.387  -0.432
20    S        -0.404  -0.396  -0.414  -0.275  -0.247  -0.301  -0.445  -0.434  -0.450
21    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
22    T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
23    V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
24    Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
25    A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
26    D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
27    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
28    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
29    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
30    E        -0.404  -0.362  -0.400  -0.654  -0.587  -0.660  -0.445  -0.387  -0.432
31    S        -1.275  -1.265  -1.239  -1.071  -1.045  -1.010  -1.024  -1.009  -0.965
32    S        -0.404  -0.393  -0.405  -0.528  -0.514  -0.523  -0.445  -0.428  -0.439
33    S        -0.404  -0.446  -0.437  -0.438  -0.482  -0.462  -0.445  -0.499  -0.481
34    F         2.210   2.226   2.270   2.356   2.384   2.449   2.449   2.473   2.539
35    I        -0.404  -0.396  -0.414  -0.608  -0.580  -0.605  -0.445  -0.434  -0.450
36    S         0.796   0.793   0.730   0.654   0.654   0.556   0.712   0.704   0.587
37    F         0.610   0.626   0.599   0.671   0.700   0.643   0.391   0.415   0.356
38    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
39    D        -0.404  -0.425  -0.427  -0.605  -0.653  -0.654  -0.445  -0.471  -0.467
40    K        -0.404  -0.393  -0.405  -0.392  -0.385  -0.404  -0.445  -0.428  -0.439
41    E        -0.404  -0.425  -0.427  -0.140  -0.168  -0.146  -0.445  -0.471  -0.467
42    S        -0.404  -0.337  -0.403  -0.669  -0.562  -0.659  -0.445  -0.354  -0.436
43    N        -0.404  -0.425  -0.427  -0.283  -0.333  -0.322  -0.445  -0.471  -0.467
44    W        -1.275  -1.265  -1.239  -0.819  -0.816  -0.756  -1.024  -1.009  -0.965
45    D        -0.404  -0.425  -0.427  -0.472  -0.511  -0.504  -0.445  -0.471  -0.467
46    T        -1.275  -1.265  -1.239  -1.071  -1.067  -1.010  -1.024  -1.009  -0.965
47    I        -1.275  -1.265  -1.239  -1.225  -1.202  -1.166  -1.024  -1.009  -0.965
48    S        -0.404  -0.425  -0.427  -0.501  -0.515  -0.522  -0.445  -0.471  -0.467
49    T        -0.404  -0.446  -0.437  -0.250  -0.332  -0.314  -0.445  -0.499  -0.481
50    I        -0.552  -0.542  -0.511  -0.453  -0.435  -0.386  -0.638  -0.623  -0.576
51    S        -0.552  -0.542  -0.511  -0.491  -0.461  -0.425  -0.638  -0.623  -0.576
52    S        -0.404  -0.425  -0.427  -0.513  -0.538  -0.535  -0.445  -0.471  -0.467
53    T        -0.404  -0.337  -0.403  -0.352  -0.256  -0.349  -0.445  -0.354  -0.436
54    A        -0.404  -0.337  -0.403  -0.418  -0.326  -0.401  -0.445  -0.354  -0.436
55    D        -1.275  -1.265  -1.239  -1.354  -1.311  -1.296  -1.024  -1.009  -0.965
56    V        -0.404  -0.446  -0.437  -0.135  -0.196  -0.174  -0.445  -0.499  -0.481
57    -        -0.552  -0.546  -0.511  -0.764  -0.762  -0.701  -0.638  -0.627  -0.576
58    -         2.210   2.226   2.270   1.855   1.881   1.943   2.449   2.473   2.539
59    -         0.610   0.613   0.612   0.129   0.131   0.123   0.391   0.393   0.378
60    -        -0.552  -0.546  -0.511  -0.811  -0.801  -0.748  -0.638  -0.627  -0.576
61    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
62    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
63    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
64    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
65    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
66    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
67    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
68    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
69    I         0.467   0.477   0.516  -0.018  -0.002   0.056   0.134   0.148   0.203
70    S        -0.404  -0.446  -0.437  -0.256  -0.287  -0.255  -0.445  -0.499  -0.481
71    S        -0.404  -0.396  -0.414  -0.426  -0.408  -0.458  -0.445  -0.434  -0.450
72    V        -0.404  -0.362  -0.400  -0.472  -0.408  -0.482  -0.445  -0.387  -0.432
73    D        -0.404  -0.393  -0.405  -0.501  -0.485  -0.504  -0.445  -0.428  -0.439
74    S        -1.275  -1.265  -1.239  -1.277  -1.245  -1.219  -1.024  -1.009  -0.965
75    A        -1.275  -1.265  -1.239  -1.085  -1.089  -1.025  -1.024  -1.009  -0.965
76    I         0.796   0.876   0.752   0.466   0.591   0.394   0.712   0.843   0.625
77    A        -0.404  -0.362  -0.400  -0.239  -0.183  -0.233  -0.445  -0.387  -0.432
78    V        -0.404  -0.446  -0.437  -0.300  -0.379  -0.363  -0.445  -0.499  -0.481
79    F        -1.275  -1.265  -1.239  -1.247  -1.213  -1.189  -1.024  -1.009  -0.965
80    E        -0.404  -0.425  -0.427  -0.135  -0.158  -0.140  -0.445  -0.471  -0.467
81    F         0.467   0.482   0.519   0.400   0.422   0.481   0.134   0.157   0.209
82    D        -0.404  -0.446  -0.437  -0.525  -0.603  -0.580  -0.445  -0.499  -0.481
83    N         0.796   0.793   0.730   0.922   0.914   0.813   0.712   0.704   0.587
84    F         0.610   0.583   0.589   0.757   0.717   0.726   0.391   0.339   0.338
85    S        -0.552  -0.542  -0.511  -0.682  -0.653  -0.618  -0.638  -0.623  -0.576
86    L         0.610   0.583   0.589   0.114   0.071   0.089   0.391   0.339   0.338
87    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
88    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
89    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
90    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
91    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
92    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
93    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
94    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
95    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
96    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
97    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
98    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
99    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
100   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
101   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
102   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
103   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
104   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
105   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
106   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
107   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
108   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
109   L         0.467   0.482   0.519   0.053   0.101   0.149   0.134   0.157   0.209
110   D         0.796   0.740   0.707   0.693   0.600   0.540   0.712   0.615   0.547
111   N        -1.275  -1.265  -1.239  -1.138  -1.139  -1.078  -1.024  -1.009  -0.965
112   L        -0.404  -0.393  -0.405  -0.563  -0.541  -0.547  -0.445  -0.428  -0.439
113   M        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
114   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
115   D         2.210   2.226   2.270   2.121   2.147   2.212   2.449   2.473   2.539
116   E        -0.404  -0.446  -0.437  -0.501  -0.572  -0.571  -0.445  -0.499  -0.481
117   E        -1.275  -1.265  -1.239  -1.025  -1.003  -0.965  -1.024  -1.009  -0.965
118   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
119   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
120   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
121   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
122   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
123   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
124   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
125   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
126   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
127   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
128   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
129   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
130   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
131   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
132   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
133   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
134   Y         0.796   0.740   0.707   1.216   1.133   1.087   0.712   0.615   0.547
135   P         2.210   2.226   2.270   2.523   2.545   2.618   2.449   2.473   2.539
136   F         0.610   0.574   0.589   0.627   0.559   0.581   0.391   0.323   0.338
137   F        -0.552  -0.541  -0.511  -0.952  -0.937  -0.890  -0.638  -0.621  -0.576
138   N        -0.404  -0.362  -0.400  -0.319  -0.256  -0.323  -0.445  -0.387  -0.432
139   R        -1.275  -1.265  -1.239  -0.749  -0.758  -0.686  -1.024  -1.009  -0.965
140   F        -1.275  -1.265  -1.239  -1.304  -1.282  -1.246  -1.024  -1.009  -0.965
141   F        -0.404  -0.446  -0.437  -0.297  -0.378  -0.361  -0.445  -0.499  -0.481
142   A        -0.404  -0.393  -0.405  -0.395  -0.378  -0.416  -0.445  -0.428  -0.439
143   N        -1.275  -1.265  -1.239  -1.145  -1.142  -1.086  -1.024  -1.009  -0.965
144   D        -0.404  -0.337  -0.403  -0.438  -0.310  -0.458  -0.445  -0.354  -0.436
145   V        -0.404  -0.393  -0.405  -0.461  -0.437  -0.482  -0.445  -0.428  -0.439
146   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
147   L        -0.404  -0.362  -0.400  -0.361  -0.274  -0.364  -0.445  -0.387  -0.432
148   T         0.796   0.740   0.707   0.929   0.827   0.760   0.712   0.615   0.547
149   V        -0.404  -0.446  -0.437  -0.490  -0.575  -0.583  -0.445  -0.499  -0.481
150   H        -0.404  -0.337  -0.403  -0.435  -0.337  -0.437  -0.445  -0.354  -0.436
151   D        -0.404  -0.393  -0.405  -0.501  -0.485  -0.504  -0.445  -0.428  -0.439
152   D        -0.404  -0.393  -0.405  -0.400  -0.383  -0.395  -0.445  -0.428  -0.439
153   S        -1.275  -1.265  -1.239  -1.174  -1.156  -1.115  -1.024  -1.009  -0.965
154   P        -0.404  -0.396  -0.414  -0.239  -0.247  -0.252  -0.445  -0.434  -0.450
155   L        -0.404  -0.425  -0.427  -0.525  -0.533  -0.526  -0.445  -0.471  -0.467
156   N        -0.404  -0.396  -0.414  -0.438  -0.427  -0.446  -0.445  -0.434  -0.450
157   I        -0.404  -0.393  -0.405  -0.313  -0.301  -0.313  -0.445  -0.428  -0.439
158   S        -1.275  -1.265  -1.239  -1.506  -1.470  -1.450  -1.024  -1.009  -0.965
159   Q        -0.404  -0.337  -0.403  -0.275  -0.190  -0.265  -0.445  -0.354  -0.436
160   S        -0.404  -0.446  -0.437  -0.545  -0.604  -0.585  -0.445  -0.499  -0.481
161   L        -0.404  -0.393  -0.405  -0.590  -0.575  -0.576  -0.445  -0.428  -0.439
162   S        -0.404  -0.425  -0.427  -0.504  -0.526  -0.525  -0.445  -0.471  -0.467
163   P        -0.404  -0.393  -0.405  -0.226  -0.211  -0.246  -0.445  -0.428  -0.439
164   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
165   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
166   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
167   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
168   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
169   I         0.796   0.829   0.735   0.964   1.008   0.889   0.712   0.766   0.597
170   M        -1.275  -1.265  -1.239  -0.927  -0.933  -0.866  -1.024  -1.009  -0.965
171   E        -0.404  -0.337  -0.403  -0.122  -0.006  -0.131  -0.445  -0.354  -0.436
172   Q        -0.404  -0.425  -0.427  -0.185  -0.217  -0.250  -0.445  -0.471  -0.467
173   F        -1.275  -1.265  -1.239  -0.937  -0.938  -0.876  -1.024  -1.009  -0.965
174   T        -1.275  -1.265  -1.239  -0.832  -0.822  -0.769  -1.024  -1.009  -0.965
175   V        -1.275  -1.265  -1.239  -1.547  -1.555  -1.492  -1.024  -1.009  -0.965
176   D        -0.404  -0.396  -0.414  -0.367  -0.349  -0.392  -0.445  -0.434  -0.450
177   E         0.610   0.574   0.589   0.685   0.632   0.663   0.391   0.323   0.338
178   L        -0.552  -0.541  -0.511  -0.806  -0.781  -0.743  -0.638  -0.621  -0.576
179   P         0.796   0.793   0.730   1.009   0.997   0.862   0.712   0.704   0.587
180   E         0.796   0.829   0.735   0.851   0.900   0.760   0.712   0.766   0.597
181   S         0.796   0.793   0.730   0.654   0.654   0.556   0.712   0.704   0.587
182   A         0.467   0.482   0.519   0.414   0.426   0.492   0.134   0.157   0.209
183   S         0.796   0.740   0.707   0.719   0.649   0.606   0.712   0.615   0.547
184   D         0.796   0.793   0.730   0.814   0.809   0.729   0.712   0.704   0.587
185   L        -0.404  -0.446  -0.437  -0.569  -0.612  -0.586  -0.445  -0.499  -0.481
186   L         2.210   2.226   2.270   1.877   1.909   1.966   2.449   2.473   2.539
187   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
188   Y         0.610   0.574   0.589   0.818   0.740   0.762   0.391   0.323   0.338
189   E        -0.552  -0.541  -0.511  -0.415  -0.390  -0.349  -0.638  -0.621  -0.576
190   Y         0.610   0.643   0.619   0.822   0.878   0.826   0.391   0.446   0.392
191   S         0.610   0.574   0.589   0.328   0.269   0.289   0.391   0.323   0.338
192   L        -0.552  -0.541  -0.511  -1.049  -1.006  -0.988  -0.638  -0.621  -0.576
193   D         0.610   0.643   0.619   0.252   0.310   0.246   0.391   0.446   0.392
194   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
195   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
196   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
197   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
198   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
199   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
200   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
201   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
202   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
203   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
204   D         2.210   2.226   2.270   2.085   2.109   2.176   2.449   2.473   2.539
205   K         0.610   0.574   0.589   0.607   0.530   0.559   0.391   0.323   0.338
206   S        -1.275  -1.265  -1.239  -1.192  -1.175  -1.133  -1.024  -1.009  -0.965
207   I        -1.275  -1.265  -1.239  -1.362  -1.350  -1.304  -1.024  -1.009  -0.965
208   V         0.796   0.793   0.730   0.809   0.800   0.665   0.712   0.704   0.587
209   L        -0.404  -0.393  -0.405  -0.632  -0.613  -0.622  -0.445  -0.428  -0.439
210   F        -0.552  -0.545  -0.511  -0.542  -0.521  -0.476  -0.638  -0.626  -0.576
211   K         0.467   0.477   0.516   0.278   0.284   0.353   0.134   0.148   0.203
212   F        -0.404  -0.446  -0.437  -0.311  -0.371  -0.377  -0.445  -0.499  -0.481
213   T         0.796   0.740   0.707   1.019   0.929   0.878   0.712   0.615   0.547
214   S         0.467   0.479   0.517   0.133   0.154   0.217   0.134   0.151   0.207
215   D        -0.404  -0.425  -0.427  -0.438  -0.464  -0.465  -0.445  -0.471  -0.467
216   A        -0.404  -0.396  -0.414  -0.386  -0.393  -0.414  -0.445  -0.434  -0.450
217   Y        -0.404  -0.446  -0.437  -0.191  -0.286  -0.273  -0.445  -0.499  -0.481
218   D        -0.404  -0.446  -0.437  -0.519  -0.596  -0.573  -0.445  -0.499  -0.481
219   L        -1.275  -1.265  -1.239  -1.312  -1.268  -1.254  -1.024  -1.009  -0.965
220   K        -1.275  -1.265  -1.239  -0.878  -0.868  -0.815  -1.024  -1.009  -0.965
221   K        -1.275  -1.265  -1.239  -1.081  -1.080  -1.021  -1.024  -1.009  -0.965
222   L         0.610   0.574   0.589   0.122   0.059   0.066   0.391   0.323   0.338
223   D         2.210   2.226   2.270   2.121   2.147   2.212   2.449   2.473   2.539
224   E        -0.404  -0.362  -0.400  -0.369  -0.304  -0.354  -0.445  -0.387  -0.432
225   F        -0.404  -0.446  -0.437  -0.297  -0.376  -0.361  -0.445  -0.499  -0.481
226   I        -0.404  -0.425  -0.427  -0.528  -0.558  -0.589  -0.445  -0.471  -0.467
227   D        -0.404  -0.425  -0.427  -0.355  -0.393  -0.373  -0.445  -0.471  -0.467
228   S        -1.275  -1.265  -1.239  -1.131  -1.091  -1.071  -1.024  -1.009  -0.965
229   C        -0.404  -0.337  -0.403  -0.090  -0.012  -0.069  -0.445  -0.354  -0.436
230   L        -1.275  -1.265  -1.239  -1.116  -1.072  -1.057  -1.024  -1.009  -0.965
231   S        -0.404  -0.362  -0.400  -0.395  -0.313  -0.405  -0.445  -0.387  -0.432
232   F        -0.404  -0.446  -0.437  -0.339  -0.420  -0.409  -0.445  -0.499  -0.481
233   L        -0.404  -0.425  -0.427  -0.548  -0.575  -0.553  -0.445  -0.471  -0.467
234   E         2.210   2.226   2.270   2.220   2.246   2.312   2.449   2.473   2.539
235   D        -0.404  -0.446  -0.437  -0.516  -0.584  -0.570  -0.445  -0.499  -0.481
236   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
237   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
238   K         0.796   0.793   0.730   0.990   0.978   0.899   0.712   0.704   0.587
239   S        -1.275  -1.265  -1.239  -1.327  -1.293  -1.269  -1.024  -1.009  -0.965
240   G        -0.404  -0.396  -0.414  -0.239  -0.238  -0.245  -0.445  -0.434  -0.450
241   D        -0.404  -0.446  -0.437  -0.718  -0.798  -0.804  -0.445  -0.499  -0.481
242   N        -0.404  -0.446  -0.437  -0.513  -0.605  -0.605  -0.445  -0.499  -0.481
243   L        -0.404  -0.337  -0.403  -0.484  -0.351  -0.504  -0.445  -0.354  -0.436
244   T        -0.552  -0.541  -0.511  -0.502  -0.494  -0.437  -0.638  -0.621  -0.576
245   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
246   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
247   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
248   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
249   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
250   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
251   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
252   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
253   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
254   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
255   N        -0.552  -0.541  -0.511  -0.624  -0.627  -0.559  -0.638  -0.621  -0.576
256   S        -0.552  -0.541  -0.511  -0.576  -0.544  -0.511  -0.638  -0.621  -0.576
257   L         0.610   0.574   0.589   0.365   0.327   0.353   0.391   0.323   0.338
258   G        -0.552  -0.541  -0.511  -0.296  -0.283  -0.228  -0.638  -0.621  -0.576
259   W        -0.552  -0.541  -0.511  -0.477  -0.459  -0.411  -0.638  -0.621  -0.576
260   A        -0.552  -0.541  -0.511  -0.772  -0.747  -0.709  -0.638  -0.621  -0.576
261   F        -0.404  -0.425  -0.427  -0.311  -0.370  -0.358  -0.445  -0.471  -0.467
262   E        -0.404  -0.337  -0.403  -0.516  -0.413  -0.516  -0.445  -0.354  -0.436
263   D        -0.404  -0.425  -0.427  -0.525  -0.575  -0.563  -0.445  -0.471  -0.467
264   E        -0.404  -0.446  -0.437  -0.516  -0.600  -0.588  -0.445  -0.499  -0.481
265   D        -1.275  -1.265  -1.239  -1.225  -1.213  -1.166  -1.024  -1.009  -0.965
266   G        -0.404  -0.396  -0.414  -0.446  -0.439  -0.444  -0.445  -0.434  -0.450
267   D        -0.404  -0.425  -0.427  -0.435  -0.469  -0.462  -0.445  -0.471  -0.467
268   D         0.796   0.740   0.707   0.816   0.737   0.700   0.712   0.615   0.547
269   E        -1.275  -1.265  -1.239  -1.092  -1.076  -1.032  -1.024  -1.009  -0.965
270   Y        -0.552  -0.541  -0.511  -0.157  -0.142  -0.088  -0.638  -0.621  -0.576
271   A         0.610   0.643   0.619   0.654   0.708   0.660   0.391   0.446   0.392
272   T         0.610   0.651   0.624   0.435   0.495   0.455   0.391   0.461   0.401
273   E         0.610   0.651   0.624   0.365   0.430   0.379   0.391   0.461   0.401
274   E        -0.552  -0.541  -0.511  -0.466  -0.464  -0.400  -0.638  -0.621  -0.576
275   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
276   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
277   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
278   H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
279   H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
280   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
281   N        -0.404  -0.425  -0.427  -0.239  -0.267  -0.273  -0.445  -0.471  -0.467
282   N         0.467   0.479   0.517   0.524   0.543   0.609   0.134   0.151   0.207
283   K         0.467   0.477   0.516   0.278   0.284   0.353   0.134   0.148   0.203
284   G         0.610   0.598   0.599   0.824   0.798   0.795   0.391   0.366   0.356
285   K         2.210   2.226   2.270   2.290   2.312   2.382   2.449   2.473   2.539
286   E        -0.552  -0.545  -0.511  -0.580  -0.570  -0.515  -0.638  -0.626  -0.576
287   G         0.610   0.637   0.621   0.901   0.942   0.917   0.391   0.436   0.396
288   D        -0.404  -0.446  -0.437  -0.605  -0.675  -0.673  -0.445  -0.499  -0.481
289   D        -1.275  -1.265  -1.239  -1.726  -1.717  -1.672  -1.024  -1.009  -0.965
290   D        -0.404  -0.446  -0.437  -0.501  -0.567  -0.553  -0.445  -0.499  -0.481
291   I        -0.552  -0.541  -0.511  -0.477  -0.463  -0.411  -0.638  -0.621  -0.576
292   L         0.610   0.574   0.589   0.252   0.204   0.220   0.391   0.323   0.338
293   S         0.796   0.740   0.707   0.706   0.636   0.589   0.712   0.615   0.547
294   S         0.796   0.793   0.730   0.741   0.744   0.664   0.712   0.704   0.587
295   I        -0.404  -0.425  -0.427  -0.528  -0.558  -0.589  -0.445  -0.471  -0.467
296   W         0.796   0.740   0.707   1.253   1.163   1.101   0.712   0.615   0.547
297   T         2.210   2.226   2.270   2.394   2.419   2.488   2.449   2.473   2.539
298   E         0.796   0.740   0.707   0.900   0.819   0.778   0.712   0.615   0.547
299   G         2.210   2.226   2.270   2.495   2.518   2.590   2.449   2.473   2.539
300   L         0.796   0.740   0.707   0.466   0.384   0.322   0.712   0.615   0.547
301   L         0.796   0.740   0.707   0.608   0.545   0.507   0.712   0.615   0.547
302   M         0.796   0.829   0.735   1.081   1.135   0.956   0.712   0.766   0.597
303   C         2.210   2.226   2.270   2.668   2.697   2.764   2.449   2.473   2.539
304   L         2.210   2.226   2.270   1.877   1.909   1.966   2.449   2.473   2.539
305   I         0.796   0.740   0.707   0.870   0.780   0.727   0.712   0.615   0.547
306   V         0.796   0.740   0.707   0.929   0.833   0.775   0.712   0.615   0.547
307   S         2.210   2.226   2.270   2.020   2.053   2.111   2.449   2.473   2.539
308   A         0.796   0.876   0.752   1.115   1.232   1.046   0.712   0.843   0.625
309   L        -0.404  -0.446  -0.437  -0.700  -0.751  -0.735  -0.445  -0.499  -0.481
310   L         2.210   2.226   2.270   1.877   1.909   1.966   2.449   2.473   2.539
311   L         0.796   0.740   0.707   0.498   0.420   0.364   0.712   0.615   0.547
312   F        -1.275  -1.265  -1.239  -1.229  -1.236  -1.170  -1.024  -1.009  -0.965
313   I         2.210   2.226   2.270   2.259   2.283   2.351   2.449   2.473   2.539
314   L         2.210   2.226   2.270   1.877   1.909   1.966   2.449   2.473   2.539
315   I        -0.404  -0.425  -0.427  -0.242  -0.270  -0.266  -0.445  -0.471  -0.467
316   V         0.467   0.482   0.519   0.330   0.346   0.407   0.134   0.157   0.209
317   A        -0.404  -0.446  -0.437  -0.319  -0.395  -0.396  -0.445  -0.499  -0.481
318   L        -0.404  -0.425  -0.427  -0.590  -0.601  -0.599  -0.445  -0.471  -0.467
319   S         2.210   2.226   2.270   2.020   2.053   2.111   2.449   2.473   2.539
320   W         2.210   2.226   2.270   2.656   2.685   2.752   2.449   2.473   2.539
321   I        -0.404  -0.396  -0.414  -0.590  -0.562  -0.585  -0.445  -0.434  -0.450
322   S        -0.404  -0.425  -0.427  -0.487  -0.512  -0.505  -0.445  -0.471  -0.467
323   N        -0.404  -0.362  -0.400  -0.651  -0.587  -0.648  -0.445  -0.387  -0.432
324   L         2.210   2.226   2.270   1.877   1.909   1.966   2.449   2.473   2.539
325   D        -0.404  -0.446  -0.437  -0.654  -0.730  -0.729  -0.445  -0.499  -0.481
326   I         2.210   2.226   2.270   2.259   2.283   2.351   2.449   2.473   2.539
327   T         0.796   0.876   0.752   0.654   0.775   0.590   0.712   0.843   0.625
328   Y         2.210   2.226   2.270   2.545   2.572   2.640   2.449   2.473   2.539
329   G         0.796   0.740   0.707   1.087   0.989   0.936   0.712   0.615   0.547
330   A         2.210   2.226   2.270   2.407   2.433   2.501   2.449   2.473   2.539
331   L         0.796   0.740   0.707   0.501   0.424   0.367   0.712   0.615   0.547
332   E         0.796   0.740   0.707   0.758   0.660   0.593   0.712   0.615   0.547
333   K         0.796   0.793   0.730   1.023   1.011   0.940   0.712   0.704   0.587
334   S        -0.404  -0.446  -0.437  -0.339  -0.380  -0.349  -0.445  -0.499  -0.481
335   T        -1.275  -1.265  -1.239  -0.995  -0.989  -0.934  -1.024  -1.009  -0.965
336   N         0.796   0.740   0.707   0.860   0.761   0.693   0.712   0.615   0.547
337   P        -0.404  -0.446  -0.437   0.018  -0.060  -0.033  -0.445  -0.499  -0.481
338   I        -1.275  -1.265  -1.239  -1.389  -1.368  -1.332  -1.024  -1.009  -0.965
339   K         2.210   2.226   2.270   2.317   2.335   2.410   2.449   2.473   2.539
340   K         2.210   2.226   2.270   2.317   2.335   2.410   2.449   2.473   2.539
341   N         0.467   0.482   0.519   0.410   0.433   0.493   0.134   0.157   0.209
342   N         0.796   0.740   0.707   0.891   0.797   0.734   0.712   0.615   0.547
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P53262
Output conservation file - output/P53262
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
