1     M         1.819   1.834   1.932   2.011   2.030   2.184   2.041   2.064   2.226
2     F        -0.340  -0.381  -0.351  -0.393  -0.454  -0.401  -0.496  -0.535  -0.479
3     K        -0.865  -0.882  -0.813  -1.077  -1.129  -1.028  -0.830  -0.846  -0.753
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    E        -0.377  -0.425  -0.386  -0.310  -0.377  -0.308  -0.520  -0.575  -0.514
12    E         0.092   0.081   0.119   0.013  -0.006   0.051  -0.219  -0.227  -0.171
13    D         0.271   0.286   0.198   0.514   0.542   0.407   0.080   0.108  -0.041
14    S         0.271   0.227   0.175   0.430   0.341   0.227   0.080   0.004  -0.081
15    L         1.171   1.100   1.011   1.114   1.026   0.918   1.234   1.109   0.914
16    R        -0.267  -0.317  -0.341  -0.224  -0.283  -0.350  -0.381  -0.434  -0.460
17    K         0.450   0.342   0.244   0.546   0.384   0.202   0.384   0.217   0.045
18    G         0.176   0.104   0.131   0.088  -0.018   0.025  -0.068  -0.171  -0.147
19    Q        -0.863  -0.834  -0.804  -0.784  -0.731  -0.683  -0.842  -0.815  -0.749
20    N        -1.161  -1.156  -1.112  -0.817  -0.806  -0.742  -0.958  -0.951  -0.873
21    V         0.554   0.530   0.321   0.682   0.646   0.318   0.542   0.505   0.166
22    A         0.450   0.494   0.281   0.390   0.455   0.117   0.384   0.449   0.103
23    A        -1.187  -1.214  -1.150  -1.005  -1.069  -0.980  -0.972  -0.992  -0.902
24    W        -0.452  -0.453  -0.405  -0.444  -0.437  -0.370  -0.612  -0.610  -0.539
25    K        -0.750  -0.797  -0.775  -0.441  -0.492  -0.450  -0.727  -0.769  -0.719
26    T        -0.750  -0.773  -0.754  -0.860  -0.874  -0.846  -0.727  -0.739  -0.695
27    L        -0.267  -0.296  -0.347  -0.387  -0.443  -0.484  -0.381  -0.426  -0.468
28    L        -0.452  -0.418  -0.397  -0.735  -0.684  -0.653  -0.612  -0.563  -0.528
29    A         1.171   1.160   1.021   1.225   1.214   1.056   1.234   1.213   0.933
30    G         1.819   1.834   1.932   1.734   1.755   1.904   2.041   2.064   2.226
31    A         0.031  -0.001   0.057  -0.320  -0.387  -0.318  -0.266  -0.319  -0.250
32    V        -0.452  -0.437  -0.401  -0.690  -0.656  -0.620  -0.612  -0.588  -0.533
33    S         0.681   0.699   0.759   0.321   0.351   0.418   0.311   0.338   0.397
34    G         1.171   1.100   1.011   1.138   1.040   0.897   1.234   1.109   0.914
35    L        -0.452  -0.442  -0.399  -0.680  -0.660  -0.574  -0.612  -0.595  -0.530
36    L        -0.267  -0.275  -0.328  -0.315  -0.325  -0.423  -0.381  -0.386  -0.442
37    A         0.144   0.098   0.142  -0.080  -0.124  -0.046  -0.150  -0.202  -0.141
38    R         1.819   1.834   1.932   1.870   1.895   2.042   2.041   2.064   2.226
39    S        -1.048  -0.962  -1.075  -0.907  -0.768  -0.988  -0.842  -0.754  -0.837
40    I        -1.161  -1.157  -1.108  -0.910  -0.892  -0.829  -0.958  -0.951  -0.870
41    T         0.681   0.712   0.765   0.420   0.475   0.530   0.311   0.366   0.410
42    A         1.819   1.834   1.932   1.763   1.782   1.933   2.041   2.064   2.226
43    P         1.819   1.834   1.932   1.979   2.000   2.152   2.041   2.064   2.226
44    M         0.271   0.216   0.188   0.170   0.095   0.066   0.080   0.006  -0.055
45    D         1.819   1.834   1.932   2.032   2.054   2.206   2.041   2.064   2.226
46    T         0.681   0.664   0.746   0.461   0.417   0.537   0.311   0.266   0.370
47    I         0.627   0.639   0.734   0.344   0.360   0.501   0.196   0.210   0.342
48    K         1.819   1.834   1.932   1.860   1.890   2.032   2.041   2.064   2.226
49    I         1.819   1.834   1.932   1.789   1.815   1.960   2.041   2.064   2.226
50    R         1.171   1.186   1.026   1.297   1.322   1.101   1.234   1.257   0.943
51    L         0.554   0.502   0.318   0.568   0.501   0.264   0.542   0.460   0.162
52    Q         1.819   1.834   1.932   1.999   2.018   2.172   2.041   2.064   2.226
53    L         0.554   0.490   0.320   0.514   0.422   0.171   0.542   0.442   0.166
54    T         0.681   0.671   0.748   0.606   0.566   0.668   0.311   0.279   0.372
55    P        -0.565  -0.599  -0.707  -0.186  -0.231  -0.397  -0.496  -0.537  -0.641
56    A        -1.459  -1.440  -1.396  -1.093  -1.083  -1.014  -1.073  -1.055  -0.978
57    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
58    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
59    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
60    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
61    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
62    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
63    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
64    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
65    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
66    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
67    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
68    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
69    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
70    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
71    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
72    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
73    N         0.327   0.293   0.201   0.350   0.299   0.179   0.196   0.141  -0.023
74    G        -0.865  -0.818  -0.804  -0.910  -0.855  -0.818  -0.830  -0.780  -0.743
75    L        -0.865  -0.873  -0.810  -0.710  -0.733  -0.651  -0.830  -0.836  -0.750
76    K        -0.865  -0.828  -0.818  -0.758  -0.704  -0.688  -0.830  -0.790  -0.758
77    P         0.327   0.353   0.225   0.499   0.536   0.335   0.196   0.230   0.015
78    F         0.327   0.273   0.209   0.413   0.341   0.215   0.196   0.109  -0.012
79    G         1.044   1.120   0.959   0.964   1.069   0.810   1.016   1.144   0.812
80    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
81    Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
82    V        -1.161  -1.163  -1.113  -1.172  -1.191  -1.108  -0.958  -0.956  -0.874
83    M        -1.459  -1.451  -1.406  -1.408  -1.393  -1.331  -1.073  -1.064  -0.986
84    E        -1.459  -1.409  -1.399  -1.120  -1.030  -1.038  -1.073  -1.029  -0.980
85    V         0.144   0.186   0.150  -0.017   0.025  -0.003  -0.150  -0.110  -0.132
86    A        -1.161  -1.169  -1.113  -1.101  -1.115  -1.038  -0.958  -0.959  -0.874
87    R        -0.750  -0.726  -0.750  -0.653  -0.616  -0.648  -0.727  -0.703  -0.696
88    S        -1.161  -1.188  -1.113  -0.930  -0.953  -0.840  -0.958  -0.975  -0.874
89    M        -0.027  -0.043  -0.224   0.080   0.060  -0.226  -0.035  -0.060  -0.297
90    I        -0.750  -0.723  -0.749  -0.749  -0.732  -0.708  -0.727  -0.705  -0.694
91    K        -0.267  -0.285  -0.332  -0.164  -0.189  -0.239  -0.381  -0.409  -0.447
92    N        -1.048  -1.097  -1.094  -0.670  -0.747  -0.752  -0.842  -0.887  -0.853
93    E         1.819   1.834   1.932   1.952   1.975   2.125   2.041   2.064   2.226
94    G         1.819   1.834   1.932   1.734   1.755   1.904   2.041   2.064   2.226
95    I        -0.042  -0.031   0.044  -0.362  -0.347  -0.251  -0.381  -0.367  -0.271
96    R        -0.267  -0.181  -0.321  -0.251  -0.135  -0.345  -0.381  -0.286  -0.433
97    S         0.271   0.268   0.191   0.115   0.105  -0.051   0.080   0.074  -0.056
98    F         0.852   0.860   0.845   0.645   0.653   0.612   0.657   0.666   0.579
99    W         1.819   1.834   1.932   2.094   2.116   2.268   2.041   2.064   2.226
100   K         1.171   1.100   1.011   1.288   1.204   1.070   1.234   1.109   0.914
101   G         1.819   1.834   1.932   1.734   1.755   1.904   2.041   2.064   2.226
102   N         1.819   1.834   1.932   1.999   2.024   2.172   2.041   2.064   2.226
103   I         0.627   0.639   0.734   0.344   0.359   0.500   0.196   0.211   0.343
104   P         1.171   1.100   1.011   1.404   1.310   1.183   1.234   1.109   0.914
105   G         0.852   0.860   0.845   0.685   0.693   0.629   0.657   0.666   0.579
106   S         0.271   0.291   0.192   0.307   0.335   0.150   0.080   0.106  -0.049
107   L         0.144   0.189   0.155  -0.183  -0.110  -0.159  -0.150  -0.080  -0.118
108   L         0.852   0.874   0.843   0.685   0.715   0.665   0.657   0.694   0.576
109   Y         1.819   1.834   1.932   1.936   1.958   2.109   2.041   2.064   2.226
110   V         0.144   0.115   0.151  -0.044  -0.075  -0.036  -0.150  -0.170  -0.124
111   T        -1.161  -1.165  -1.120  -1.276  -1.266  -1.204  -0.958  -0.954  -0.878
112   Y         1.819   1.834   1.932   1.936   1.958   2.109   2.041   2.064   2.226
113   G         1.171   1.170   1.023   1.146   1.144   0.933   1.234   1.229   0.937
114   S         0.271   0.305   0.205   0.115   0.174  -0.022   0.080   0.138  -0.031
115   A        -0.340  -0.306  -0.341  -0.469  -0.433  -0.464  -0.496  -0.460  -0.468
116   Q         1.171   1.100   1.011   1.437   1.345   1.229   1.234   1.109   0.914
117   F         1.819   1.834   1.932   1.894   1.913   2.066   2.041   2.064   2.226
118   S        -0.452  -0.458  -0.412  -0.686  -0.699  -0.633  -0.612  -0.618  -0.546
119   S         0.271   0.196   0.171   0.100  -0.014  -0.078   0.080  -0.029  -0.083
120   Y         1.171   1.100   1.011   1.367   1.276   1.151   1.234   1.109   0.914
121   S        -0.027  -0.047  -0.232   0.051   0.031  -0.229  -0.035  -0.061  -0.307
122   L        -1.757  -1.743  -1.664  -1.518  -1.486  -1.381  -1.188  -1.175  -1.072
123   F        -0.452  -0.462  -0.403  -0.655  -0.675  -0.587  -0.612  -0.619  -0.535
124   N        -0.750  -0.767  -0.752  -0.695  -0.690  -0.703  -0.727  -0.733  -0.694
125   R        -1.161  -1.174  -1.132  -0.892  -0.887  -0.835  -0.958  -0.963  -0.888
126   Y        -1.161  -1.138  -1.108  -1.155  -1.134  -1.093  -0.958  -0.938  -0.870
127   L        -0.565  -0.577  -0.677  -0.524  -0.554  -0.679  -0.496  -0.512  -0.608
128   T        -1.048  -1.110  -1.094  -0.893  -0.965  -0.927  -0.842  -0.898  -0.853
129   P        -1.048  -1.020  -1.069  -0.874  -0.832  -0.893  -0.842  -0.815  -0.831
130   -        -1.262  -1.250  -1.166  -1.334  -1.313  -1.196  -1.035  -1.021  -0.915
131   -        -0.467  -0.484  -0.422  -0.456  -0.488  -0.400  -0.625  -0.638  -0.553
132   -        -0.949  -0.932  -0.851  -0.721  -0.686  -0.576  -0.912  -0.893  -0.789
133   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
134   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
135   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
136   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
137   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
138   F        -1.161  -1.136  -1.108  -1.057  -1.031  -0.962  -0.958  -0.933  -0.870
139   G        -1.459  -1.468  -1.400  -1.211  -1.238  -1.143  -1.073  -1.076  -0.982
140   L        -0.340  -0.368  -0.342  -0.510  -0.536  -0.478  -0.496  -0.522  -0.470
141   E        -0.027  -0.105  -0.244   0.088  -0.008  -0.187  -0.035  -0.140  -0.323
142   A        -1.161  -1.156  -1.112  -0.953  -0.941  -0.858  -0.958  -0.951  -0.873
143   R        -1.161  -1.169  -1.118  -1.057  -1.051  -0.995  -0.958  -0.961  -0.878
144   L        -1.161  -1.103  -1.118  -1.270  -1.202  -1.192  -0.958  -0.908  -0.878
145   H        -0.750  -0.796  -0.769  -0.399  -0.474  -0.428  -0.727  -0.769  -0.715
146   S         0.554   0.502   0.318   0.583   0.523   0.259   0.542   0.460   0.162
147   L         0.144   0.142   0.134  -0.040  -0.043  -0.001  -0.150  -0.160  -0.152
148   V        -0.267  -0.281  -0.339  -0.388  -0.431  -0.530  -0.381  -0.407  -0.460
149   V         0.144   0.098   0.137   0.031  -0.020   0.054  -0.150  -0.202  -0.149
150   G         1.819   1.834   1.932   1.734   1.755   1.904   2.041   2.064   2.226
151   A        -0.267  -0.249  -0.317  -0.411  -0.377  -0.507  -0.381  -0.354  -0.429
152   F        -0.863  -0.860  -0.812  -1.166  -1.158  -1.077  -0.842  -0.833  -0.755
153   A         0.852   0.938   0.883   0.677   0.819   0.691   0.657   0.815   0.657
154   G         1.819   1.834   1.932   1.734   1.755   1.904   2.041   2.064   2.226
155   I        -0.750  -0.725  -0.746  -0.768  -0.729  -0.786  -0.727  -0.698  -0.690
156   T        -0.750  -0.757  -0.766  -0.779  -0.792  -0.815  -0.727  -0.730  -0.712
157   S         0.681   0.664   0.746   0.321   0.281   0.392   0.311   0.266   0.370
158   S         0.681   0.695   0.761   0.383   0.403   0.477   0.311   0.331   0.401
159   I        -0.750  -0.713  -0.740  -0.905  -0.863  -0.885  -0.727  -0.690  -0.687
160   V        -0.267  -0.280  -0.324  -0.274  -0.314  -0.376  -0.381  -0.402  -0.440
161   S         0.627   0.640   0.734   0.249   0.266   0.403   0.196   0.214   0.344
162   Y         1.819   1.834   1.932   1.936   1.958   2.109   2.041   2.064   2.226
163   P         1.819   1.834   1.932   1.979   2.000   2.152   2.041   2.064   2.226
164   F         0.681   0.672   0.744   0.440   0.401   0.483   0.311   0.282   0.365
165   D         1.819   1.834   1.932   2.032   2.054   2.206   2.041   2.064   2.226
166   V         0.271   0.209   0.190   0.089  -0.003  -0.042   0.080  -0.005  -0.053
167   L         0.554   0.466   0.308   0.560   0.447   0.237   0.542   0.407   0.146
168   R         1.819   1.834   1.932   1.870   1.895   2.042   2.041   2.064   2.226
169   T         1.819   1.834   1.932   1.808   1.827   1.979   2.041   2.064   2.226
170   R         0.554   0.466   0.308   0.699   0.581   0.314   0.542   0.407   0.146
171   L         0.627   0.643   0.736   0.286   0.320   0.455   0.196   0.221   0.347
172   V         0.271   0.312   0.206   0.165   0.236   0.053   0.080   0.151  -0.029
173   A         1.171   1.100   1.011   1.167   1.068   0.926   1.234   1.109   0.914
174   N         0.271   0.196   0.171   0.481   0.375   0.330   0.080  -0.029  -0.083
175   N        -1.161  -1.155  -1.119  -1.226  -1.217  -1.147  -0.958  -0.949  -0.878
176   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
177   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
178   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
179   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
180   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
181   Q        -0.846  -0.829  -0.802  -0.648  -0.634  -0.585  -0.821  -0.803  -0.745
182   M        -1.187  -1.183  -1.128  -1.160  -1.148  -1.086  -0.972  -0.965  -0.883
183   H        -1.048  -1.072  -1.075  -0.631  -0.669  -0.694  -0.842  -0.864  -0.836
184   S        -1.161  -1.155  -1.119  -1.184  -1.174  -1.129  -0.958  -0.949  -0.878
185   M        -0.863  -0.851  -0.806  -0.904  -0.862  -0.792  -0.842  -0.826  -0.751
186   S         0.554   0.490   0.320   0.604   0.532   0.301   0.542   0.442   0.166
187   I        -0.340  -0.327  -0.350  -0.408  -0.402  -0.421  -0.496  -0.480  -0.478
188   T        -1.161  -1.161  -1.112  -1.242  -1.250  -1.166  -0.958  -0.953  -0.873
189   R        -1.459  -1.430  -1.406  -1.123  -1.062  -1.056  -1.073  -1.048  -0.985
190   E        -0.042  -0.049   0.039  -0.237  -0.258  -0.132  -0.381  -0.391  -0.278
191   V        -1.048  -1.103  -1.095  -0.910  -1.004  -0.984  -0.842  -0.892  -0.855
192   R         0.271   0.286   0.193   0.319   0.349   0.208   0.080   0.102  -0.049
193   D        -1.161  -1.180  -1.118  -1.063  -1.097  -0.997  -0.958  -0.968  -0.878
194   I         1.171   1.200   1.028   1.238   1.279   1.065   1.234   1.279   0.946
195   W         0.144   0.201   0.148   0.234   0.307   0.249  -0.150  -0.082  -0.130
196   K        -0.750  -0.716  -0.750  -0.804  -0.769  -0.825  -0.727  -0.698  -0.696
197   L        -1.459  -1.464  -1.402  -1.263  -1.273  -1.154  -1.073  -1.073  -0.983
198   E         0.554   0.544   0.324   0.830   0.805   0.510   0.542   0.520   0.172
199   G         1.819   1.834   1.932   1.734   1.755   1.904   2.041   2.064   2.226
200   L        -0.452  -0.459  -0.413  -0.642  -0.651  -0.573  -0.612  -0.615  -0.546
201   P        -1.459  -1.472  -1.403  -1.298  -1.320  -1.225  -1.073  -1.079  -0.983
202   G         1.819   1.834   1.932   1.734   1.755   1.904   2.041   2.064   2.226
203   F         0.554   0.610   0.345   0.756   0.828   0.458   0.542   0.623   0.205
204   F         0.554   0.681   0.342   0.807   0.961   0.540   0.542   0.730   0.199
205   K        -1.161  -1.151  -1.117  -1.105  -1.073  -1.048  -0.958  -0.946  -0.877
206   G         1.819   1.834   1.932   1.734   1.755   1.904   2.041   2.064   2.226
207   S        -0.750  -0.742  -0.747  -0.857  -0.840  -0.832  -0.727  -0.710  -0.692
208   I        -1.161  -1.138  -1.108  -1.289  -1.253  -1.207  -0.958  -0.938  -0.870
209   A        -0.750  -0.788  -0.765  -0.694  -0.763  -0.749  -0.727  -0.762  -0.711
210   S         0.031   0.088   0.088  -0.320  -0.217  -0.259  -0.266  -0.179  -0.202
211   M        -0.267  -0.317  -0.341  -0.185  -0.257  -0.344  -0.381  -0.434  -0.460
212   T        -0.452  -0.419  -0.392  -0.728  -0.655  -0.633  -0.612  -0.565  -0.519
213   T        -0.452  -0.458  -0.418  -0.551  -0.549  -0.467  -0.612  -0.620  -0.552
214   I         0.681   0.735   0.774   0.445   0.540   0.575   0.311   0.413   0.430
215   T        -0.863  -0.835  -0.804  -1.103  -1.065  -1.025  -0.842  -0.816  -0.750
216   L        -0.042   0.000   0.059  -0.338  -0.253  -0.188  -0.381  -0.326  -0.250
217   T        -0.452  -0.411  -0.409  -0.525  -0.440  -0.460  -0.612  -0.557  -0.542
218   A         0.031  -0.002   0.060  -0.106  -0.173  -0.083  -0.266  -0.319  -0.245
219   S         0.271   0.282   0.192   0.098   0.116  -0.057   0.080   0.100  -0.050
220   I        -0.340  -0.384  -0.368  -0.508  -0.542  -0.502  -0.496  -0.537  -0.497
221   M         0.681   0.664   0.746   0.660   0.611   0.728   0.311   0.266   0.370
222   F         1.819   1.834   1.932   1.894   1.913   2.066   2.041   2.064   2.226
223   G        -1.161  -1.186  -1.133  -0.939  -0.983  -0.904  -0.958  -0.972  -0.889
224   T        -0.452  -0.490  -0.418  -0.657  -0.704  -0.591  -0.612  -0.646  -0.552
225   Y         1.819   1.834   1.932   1.936   1.958   2.109   2.041   2.064   2.226
226   E         0.554   0.466   0.308   0.793   0.673   0.416   0.542   0.407   0.146
227   T        -0.750  -0.772  -0.757  -0.904  -0.921  -0.920  -0.727  -0.738  -0.699
228   I        -0.863  -0.884  -0.810  -1.075  -1.111  -1.009  -0.842  -0.854  -0.754
229   R        -0.267  -0.313  -0.334  -0.159  -0.219  -0.245  -0.381  -0.437  -0.452
230   I        -0.750  -0.781  -0.774  -0.632  -0.673  -0.640  -0.727  -0.747  -0.716
231   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
232   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
233   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
234   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
235   Y        -0.750  -0.734  -0.749  -0.682  -0.666  -0.690  -0.727  -0.713  -0.695
236   C        -0.452  -0.458  -0.418  -0.617  -0.638  -0.563  -0.612  -0.620  -0.552
237   D        -0.452  -0.462  -0.418  -0.396  -0.427  -0.347  -0.612  -0.623  -0.553
238   E        -0.452  -0.496  -0.419  -0.337  -0.393  -0.281  -0.612  -0.654  -0.552
239   N        -0.863  -0.851  -0.806  -0.753  -0.751  -0.655  -0.842  -0.826  -0.751
240   E        -1.048  -1.028  -1.069  -0.752  -0.736  -0.798  -0.842  -0.823  -0.831
241   K        -0.377  -0.357  -0.385  -0.343  -0.313  -0.368  -0.520  -0.496  -0.512
242   T        -0.846  -0.852  -0.804  -0.896  -0.913  -0.824  -0.821  -0.821  -0.746
243   T        -1.262  -1.256  -1.166  -1.370  -1.367  -1.232  -1.035  -1.025  -0.915
244   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
245   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
246   H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
247   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
248   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
249   W        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
250   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
251   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
252   A        -0.846  -0.841  -0.803  -0.921  -0.936  -0.894  -0.821  -0.810  -0.745
253   T        -0.846  -0.847  -0.803  -0.928  -0.948  -0.866  -0.821  -0.816  -0.746
254   L        -1.048  -1.064  -1.075  -1.106  -1.143  -1.160  -0.842  -0.857  -0.836
255   N        -0.042  -0.031   0.051  -0.196  -0.187  -0.066  -0.381  -0.365  -0.260
256   H        -0.565  -0.577  -0.681  -0.426  -0.449  -0.593  -0.496  -0.511  -0.613
257   S        -1.161  -1.119  -1.114  -1.333  -1.282  -1.255  -0.958  -0.921  -0.874
258   A         0.031   0.063   0.095  -0.127  -0.100  -0.059  -0.266  -0.221  -0.193
259   G         1.819   1.834   1.932   1.734   1.755   1.904   2.041   2.064   2.226
260   T        -1.161  -1.152  -1.126  -1.096  -1.094  -1.058  -0.958  -0.944  -0.884
261   I         0.554   0.530   0.321   0.660   0.635   0.333   0.542   0.505   0.166
262   G         0.554   0.559   0.333   0.576   0.582   0.225   0.542   0.549   0.186
263   G         1.171   1.170   1.023   1.138   1.137   0.917   1.234   1.229   0.937
264   V        -0.452  -0.458  -0.413  -0.590  -0.606  -0.528  -0.612  -0.615  -0.547
265   I        -1.048  -1.103  -1.095  -0.949  -1.052  -1.044  -0.842  -0.892  -0.855
266   A         0.681   0.703   0.754   0.321   0.359   0.408   0.311   0.347   0.386
267   K         1.819   1.834   1.932   1.860   1.890   2.032   2.041   2.064   2.226
268   I        -0.863  -0.850  -0.807  -1.116  -1.095  -1.039  -0.842  -0.825  -0.752
269   I        -0.750  -0.733  -0.745  -0.869  -0.839  -0.862  -0.727  -0.704  -0.690
270   T         0.271   0.209   0.178   0.264   0.178   0.125   0.080  -0.006  -0.076
271   F         1.819   1.834   1.932   1.894   1.913   2.066   2.041   2.064   2.226
272   P         1.819   1.834   1.932   1.979   2.000   2.152   2.041   2.064   2.226
273   L         0.554   0.502   0.318   0.514   0.441   0.167   0.542   0.460   0.162
274   E         1.171   1.175   1.022   1.470   1.478   1.278   1.234   1.238   0.935
275   T         1.171   1.170   1.023   1.206   1.204   0.980   1.234   1.229   0.937
276   I        -0.042  -0.033   0.041  -0.390  -0.367  -0.267  -0.381  -0.368  -0.274
277   R         1.171   1.100   1.011   1.296   1.206   1.075   1.234   1.109   0.914
278   R         0.681   0.695   0.761   0.516   0.544   0.620   0.311   0.331   0.401
279   R         1.171   1.100   1.011   1.289   1.198   1.062   1.234   1.109   0.914
280   M        -0.452  -0.426  -0.403  -0.525  -0.522  -0.434  -0.612  -0.591  -0.535
281   Q         1.819   1.834   1.932   1.999   2.018   2.172   2.041   2.064   2.226
282   F        -0.863  -0.850  -0.807  -0.810  -0.813  -0.736  -0.842  -0.825  -0.752
283   M        -1.161  -1.134  -1.124  -0.833  -0.805  -0.782  -0.958  -0.934  -0.882
284   N        -0.452  -0.469  -0.413  -0.518  -0.518  -0.456  -0.612  -0.620  -0.545
285   S        -0.565  -0.494  -0.681  -0.481  -0.376  -0.645  -0.496  -0.413  -0.613
286   K        -0.472  -0.481  -0.428  -0.424  -0.438  -0.364  -0.616  -0.626  -0.557
287   H        -0.472  -0.470  -0.416  -0.341  -0.336  -0.244  -0.616  -0.614  -0.542
288   L        -0.949  -0.941  -0.851  -1.142  -1.132  -1.002  -0.912  -0.901  -0.789
289   E        -0.472  -0.472  -0.428  -0.463  -0.466  -0.421  -0.616  -0.615  -0.557
290   K        -0.472  -0.440  -0.426  -0.386  -0.338  -0.325  -0.616  -0.576  -0.555
291   F        -0.472  -0.481  -0.428  -0.404  -0.423  -0.345  -0.616  -0.626  -0.557
292   S        -0.949  -0.941  -0.851  -0.840  -0.820  -0.697  -0.912  -0.901  -0.789
293   R         0.005  -0.001   0.072  -0.210  -0.225  -0.125  -0.321  -0.328  -0.232
294   H        -0.949  -0.941  -0.851  -0.795  -0.789  -0.651  -0.912  -0.901  -0.789
295   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
296   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
297   S        -0.865  -0.860  -0.804  -0.818  -0.812  -0.751  -0.830  -0.822  -0.744
298   S        -0.865  -0.859  -0.810  -0.800  -0.794  -0.751  -0.830  -0.821  -0.750
299   V         0.790   0.821   0.806   0.683   0.732   0.662   0.535   0.589   0.497
300   Y        -0.165  -0.107  -0.287   0.162   0.235   0.008  -0.219  -0.143  -0.380
301   G        -1.187  -1.191  -1.132  -0.971  -0.977  -0.866  -0.972  -0.972  -0.887
302   S        -0.472  -0.472  -0.428  -0.732  -0.744  -0.683  -0.616  -0.615  -0.557
303   Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
304   K        -0.505  -0.512  -0.432  -0.457  -0.456  -0.332  -0.671  -0.672  -0.567
305   G        -0.846  -0.808  -0.793  -0.836  -0.782  -0.740  -0.821  -0.783  -0.737
306   Y        -0.377  -0.343  -0.365  -0.345  -0.304  -0.340  -0.520  -0.488  -0.490
307   G        -1.161  -1.114  -1.105  -1.209  -1.142  -1.114  -0.958  -0.917  -0.868
308   F        -0.750  -0.724  -0.751  -0.670  -0.609  -0.649  -0.727  -0.688  -0.692
309   A        -1.757  -1.743  -1.664  -1.803  -1.761  -1.669  -1.188  -1.175  -1.072
310   R        -1.757  -1.743  -1.664  -1.391  -1.379  -1.254  -1.188  -1.175  -1.072
311   I        -1.048  -1.072  -1.083  -0.873  -0.886  -0.920  -0.842  -0.864  -0.844
312   G        -1.161  -1.139  -1.114  -1.087  -1.075  -1.004  -0.958  -0.937  -0.875
313   L        -1.459  -1.411  -1.392  -1.460  -1.398  -1.358  -1.073  -1.031  -0.976
314   Q        -0.750  -0.766  -0.765  -0.766  -0.801  -0.780  -0.727  -0.744  -0.711
315   I         1.171   1.186   1.026   1.238   1.263   1.063   1.234   1.257   0.943
316   L        -0.267  -0.337  -0.345  -0.399  -0.497  -0.505  -0.381  -0.462  -0.466
317   K        -0.340  -0.340  -0.349  -0.324  -0.315  -0.308  -0.496  -0.490  -0.476
318   Q        -0.340  -0.353  -0.362  -0.188  -0.207  -0.219  -0.496  -0.506  -0.491
319   E         1.171   1.100   1.011   1.357   1.261   1.115   1.234   1.109   0.914
320   G         1.819   1.834   1.932   1.734   1.755   1.904   2.041   2.064   2.226
321   V        -0.267  -0.284  -0.324  -0.175  -0.203  -0.238  -0.381  -0.403  -0.440
322   S        -0.863  -0.878  -0.816  -0.981  -0.998  -0.923  -0.842  -0.849  -0.759
323   S         0.271   0.291   0.192   0.087   0.113  -0.066   0.080   0.106  -0.049
324   L         1.171   1.246   1.031   1.098   1.190   0.917   1.234   1.354   0.953
325   Y         1.819   1.834   1.932   1.936   1.958   2.109   2.041   2.064   2.226
326   R         0.681   0.721   0.770   0.520   0.596   0.642   0.311   0.385   0.421
327   G         1.819   1.834   1.932   1.734   1.755   1.904   2.041   2.064   2.226
328   I        -0.340  -0.332  -0.349  -0.497  -0.500  -0.509  -0.496  -0.483  -0.476
329   L        -0.452  -0.421  -0.407  -0.777  -0.743  -0.735  -0.612  -0.583  -0.541
330   V         0.031   0.097   0.106  -0.055   0.054   0.054  -0.266  -0.166  -0.175
331   A         0.554   0.572   0.329   0.529   0.558   0.179   0.542   0.568   0.179
332   L        -0.027   0.016  -0.218  -0.008   0.051  -0.278  -0.035   0.017  -0.289
333   S        -0.750  -0.752  -0.761  -0.845  -0.850  -0.835  -0.727  -0.726  -0.707
334   K         1.819   1.834   1.932   1.860   1.890   2.032   2.041   2.064   2.226
335   T        -0.267  -0.309  -0.322  -0.411  -0.464  -0.501  -0.381  -0.423  -0.435
336   I         0.271   0.282   0.192   0.178   0.193   0.042   0.080   0.100  -0.050
337   P         1.819   1.834   1.932   1.979   2.000   2.152   2.041   2.064   2.226
338   T        -0.027  -0.096  -0.241   0.041  -0.072  -0.333  -0.035  -0.128  -0.319
339   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
340   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
341   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
342   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
343   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
344   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
345   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
346   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
347   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
348   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
349   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
350   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
351   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
352   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
353   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
354   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
355   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
356   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
357   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
358   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
359   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
360   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
361   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
362   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
363   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
364   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
365   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
366   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
367   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
368   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
369   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
370   T         0.144   0.096   0.136  -0.114  -0.170  -0.108  -0.150  -0.205  -0.148
371   F         1.171   1.175   1.022   1.194   1.199   0.997   1.234   1.238   0.935
372   V         0.852   0.851   0.821   0.751   0.748   0.664   0.657   0.648   0.528
373   S         0.681   0.664   0.746   0.346   0.309   0.423   0.311   0.266   0.370
374   F         0.144   0.134   0.134  -0.010  -0.013   0.011  -0.150  -0.169  -0.153
375   W        -0.340  -0.387  -0.355  -0.199  -0.264  -0.214  -0.496  -0.539  -0.483
376   G        -1.048  -1.047  -1.077  -0.966  -0.984  -1.036  -0.842  -0.840  -0.838
377   Y         1.171   1.160   1.021   1.367   1.356   1.167   1.234   1.213   0.933
378   E         1.819   1.834   1.932   1.952   1.975   2.125   2.041   2.064   2.226
379   T        -1.161  -1.189  -1.125  -1.027  -1.061  -0.985  -0.958  -0.974  -0.883
380   A        -0.452  -0.460  -0.417  -0.707  -0.723  -0.647  -0.612  -0.622  -0.552
381   I         0.271   0.282   0.192   0.149   0.164   0.037   0.080   0.100  -0.050
382   H        -1.048  -1.089  -1.094  -0.792  -0.834  -0.800  -0.842  -0.879  -0.854
383   Y        -1.459  -1.445  -1.398  -1.502  -1.493  -1.409  -1.073  -1.059  -0.980
384   L        -0.267  -0.208  -0.297  -0.405  -0.304  -0.426  -0.381  -0.292  -0.398
385   R        -0.165  -0.108  -0.262   0.012   0.098  -0.140  -0.219  -0.143  -0.347
386   M        -1.527  -1.512  -1.433  -1.096  -1.082  -0.955  -1.123  -1.107  -1.004
387   -        -0.865  -0.808  -0.808  -0.941  -0.866  -0.850  -0.830  -0.770  -0.748
388   -        -1.262  -1.245  -1.166  -1.279  -1.255  -1.140  -1.035  -1.017  -0.915
389   -        -0.467  -0.447  -0.413  -0.724  -0.695  -0.638  -0.625  -0.602  -0.544
390   -        -1.262  -1.245  -1.166  -1.060  -1.012  -0.919  -1.035  -1.017  -0.915
391   -         0.080   0.136   0.112  -0.013   0.049   0.056  -0.214  -0.145  -0.177
392   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
393   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
394   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
395   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
396   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
397   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
398   Y        -1.187  -1.149  -1.128  -1.215  -1.161  -1.131  -0.972  -0.934  -0.883
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P53257
Output conservation file - output/P53257
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
