1     M         1.661   1.662   1.673   1.956   1.956   1.975   1.768   1.768   1.782
2     S        -0.040  -0.040  -0.095  -0.402  -0.399  -0.473  -0.120  -0.120  -0.205
3     S        -0.191  -0.191  -0.178  -0.646  -0.646  -0.623  -0.356  -0.356  -0.335
4     A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     C        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
19    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
20    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
21    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
22    F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
23    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
24    C        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
25    V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
26    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
27    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
28    F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
29    I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
30    H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
31    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
32    F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
33    T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
34    R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
35    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
36    R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
37    T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
38    R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
39    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
40    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
41    Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
42    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
43    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
44    D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
45    E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
46    R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
47    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
48    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
49    V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
50    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
51    Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
52    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
53    I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
54    V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
55    Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
56    V        -0.191  -0.191  -0.178  -0.132  -0.131  -0.110  -0.356  -0.356  -0.335
57    A         1.661   1.662   1.673   1.653   1.654   1.673   1.768   1.768   1.782
58    M        -0.191  -0.191  -0.178   0.048   0.049   0.070  -0.356  -0.356  -0.335
59    N        -0.191  -0.191  -0.178  -0.159  -0.159  -0.137  -0.356  -0.356  -0.335
60    K         1.661   1.662   1.673   1.691   1.692   1.711   1.768   1.768   1.782
61    S        -0.191  -0.191  -0.178  -0.428  -0.428  -0.405  -0.356  -0.356  -0.335
62    S        -0.191  -0.191  -0.178  -0.772  -0.772  -0.749  -0.356  -0.356  -0.335
63    K        -0.040  -0.040  -0.095  -0.252  -0.251  -0.373  -0.120  -0.120  -0.205
64    A        -0.040  -0.018  -0.085   0.242   0.279   0.163  -0.120  -0.086  -0.188
65    F         1.661   1.662   1.673   1.802   1.804   1.822   1.768   1.768   1.782
66    Q        -1.275  -1.274  -1.261  -0.876  -0.881  -0.853  -1.064  -1.063  -1.041
67    V        -0.040  -0.061  -0.081   0.090   0.050   0.016  -0.120  -0.152  -0.183
68    P        -1.275  -1.274  -1.261  -0.964  -0.965  -0.941  -1.064  -1.063  -1.041
69    N        -0.191  -0.191  -0.178  -0.173  -0.173  -0.151  -0.356  -0.356  -0.335
70    K        -0.191  -0.191  -0.178  -0.104  -0.104  -0.082  -0.356  -0.356  -0.335
71    V        -0.040  -0.040  -0.095   0.153   0.150   0.065  -0.120  -0.120  -0.205
72    I         1.661   1.662   1.673   1.753   1.755   1.773   1.768   1.768   1.782
73    T         1.661   1.662   1.673   1.678   1.678   1.698   1.768   1.768   1.782
74    K        -1.275  -1.274  -1.261  -1.121  -1.119  -1.098  -1.064  -1.063  -1.041
75    E        -1.275  -1.274  -1.261  -0.934  -0.929  -0.911  -1.064  -1.063  -1.041
76    D        -0.040  -0.040  -0.095  -0.167  -0.167  -0.249  -0.120  -0.120  -0.205
77    I         1.661   1.662   1.673   1.753   1.755   1.773   1.768   1.768   1.782
78    T        -0.040  -0.061  -0.081  -0.187  -0.229  -0.279  -0.120  -0.152  -0.183
79    P         1.661   1.662   1.673   1.843   1.844   1.863   1.768   1.768   1.782
80    L         1.661   1.662   1.673   1.611   1.611   1.631   1.768   1.768   1.782
81    S        -1.275  -1.274  -1.261  -1.168  -1.148  -1.144  -1.064  -1.063  -1.041
82    R        -1.275  -1.274  -1.261  -1.014  -1.019  -0.990  -1.064  -1.063  -1.041
83    S        -0.040  -0.018  -0.085  -0.107  -0.060  -0.209  -0.120  -0.086  -0.188
84    H        -1.275  -1.274  -1.261  -1.024  -1.031  -1.001  -1.064  -1.063  -1.041
85    T        -1.275  -1.274  -1.261  -1.443  -1.442  -1.419  -1.064  -1.063  -1.041
86    K        -0.040  -0.061  -0.081   0.037   0.007  -0.019  -0.120  -0.152  -0.183
87    K        -1.275  -1.274  -1.261  -1.302  -1.295  -1.279  -1.064  -1.063  -1.041
88    A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
89    D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
90    T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
91    R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
92    G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
93    T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
94    A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
95    D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
96    G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
97    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
98    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
99    T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
100   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
101   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
102   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
103   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
104   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
105   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
106   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
107   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
108   P        -0.040  -0.040  -0.095  -0.029  -0.027  -0.157  -0.120  -0.120  -0.205
109   I        -1.275  -1.274  -1.261  -1.024  -1.024  -1.001  -1.064  -1.063  -1.041
110   I        -1.275  -1.274  -1.261  -1.275  -1.273  -1.251  -1.064  -1.063  -1.041
111   I        -1.275  -1.274  -1.261  -0.833  -0.829  -0.810  -1.064  -1.063  -1.041
112   T        -0.040  -0.061  -0.081   0.025  -0.009  -0.041  -0.120  -0.152  -0.183
113   T        -1.275  -1.274  -1.261  -1.184  -1.180  -1.160  -1.064  -1.063  -1.041
114   A        -0.040  -0.018  -0.085   0.063   0.098  -0.010  -0.120  -0.086  -0.188
115   R        -0.040  -0.018  -0.085  -0.297  -0.267  -0.341  -0.120  -0.086  -0.188
116   S        -1.275  -1.274  -1.261  -1.584  -1.572  -1.561  -1.064  -1.063  -1.041
117   I        -0.040  -0.061  -0.081   0.139   0.106   0.076  -0.120  -0.152  -0.183
118   D        -0.040  -0.061  -0.081  -0.385  -0.424  -0.473  -0.120  -0.152  -0.183
119   T        -1.275  -1.274  -1.261  -0.924  -0.919  -0.901  -1.064  -1.063  -1.041
120   A        -1.275  -1.274  -1.261  -0.999  -0.998  -0.975  -1.064  -1.063  -1.041
121   G        -0.040  -0.018  -0.085  -0.135  -0.102  -0.197  -0.120  -0.086  -0.188
122   S        -1.275  -1.274  -1.261  -1.363  -1.350  -1.340  -1.064  -1.063  -1.041
123   L         1.661   1.662   1.673   1.611   1.611   1.631   1.768   1.768   1.782
124   S        -1.275  -1.274  -1.261  -1.205  -1.188  -1.181  -1.064  -1.063  -1.041
125   E        -0.040  -0.040  -0.095  -0.147  -0.146  -0.271  -0.120  -0.120  -0.205
126   N        -0.191  -0.191  -0.178  -0.031  -0.031  -0.009  -0.356  -0.356  -0.335
127   A        -0.191  -0.191  -0.178  -0.186  -0.186  -0.164  -0.356  -0.356  -0.335
128   T        -0.191  -0.191  -0.178  -0.256  -0.256  -0.234  -0.356  -0.356  -0.335
129   E        -0.191  -0.191  -0.178  -0.554  -0.554  -0.532  -0.356  -0.356  -0.335
130   D         1.661   1.662   1.673   1.498   1.498   1.518   1.768   1.768   1.782
131   D        -0.191  -0.191  -0.178  -0.256  -0.256  -0.234  -0.356  -0.356  -0.335
132   G         1.661   1.662   1.673   1.748   1.749   1.768   1.768   1.768   1.782
133   T        -0.191  -0.191  -0.178  -0.631  -0.631  -0.608  -0.356  -0.356  -0.335
134   Q        -0.191  -0.191  -0.178   0.002   0.003   0.024  -0.356  -0.356  -0.335
135   N        -0.191  -0.191  -0.178  -0.298  -0.298  -0.276  -0.356  -0.356  -0.335
136   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
137   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
138   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
139   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
140   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
141   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
142   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
143   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
144   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
145   G         1.661   1.662   1.673   1.748   1.749   1.768   1.768   1.768   1.782
146   D        -0.040  -0.061  -0.081  -0.147  -0.177  -0.205  -0.120  -0.152  -0.183
147   L        -1.275  -1.274  -1.261  -1.009  -1.006  -0.985  -1.064  -1.063  -1.041
148   H        -0.040  -0.040  -0.095   0.209   0.206   0.112  -0.120  -0.120  -0.205
149   D        -0.040  -0.061  -0.081  -0.199  -0.232  -0.264  -0.120  -0.152  -0.183
150   D         1.661   1.662   1.673   1.475   1.476   1.495   1.768   1.768   1.782
151   D         1.661   1.662   1.673   1.498   1.498   1.518   1.768   1.768   1.782
152   D         1.661   1.662   1.673   1.498   1.498   1.518   1.768   1.768   1.782
153   D        -0.191  -0.191  -0.178  -0.384  -0.384  -0.362  -0.356  -0.356  -0.335
154   D        -0.191  -0.191  -0.178  -0.391  -0.391  -0.369  -0.356  -0.356  -0.335
155   D         1.661   1.662   1.673   1.498   1.498   1.518   1.768   1.768   1.782
156   L        -0.191  -0.191  -0.178  -0.193  -0.193  -0.171  -0.356  -0.356  -0.335
157   E         1.661   1.662   1.673   1.767   1.767   1.786   1.768   1.768   1.782
158   S        -0.191  -0.191  -0.178  -0.334  -0.334  -0.312  -0.356  -0.356  -0.335
159   T        -0.191  -0.191  -0.178  -0.263  -0.263  -0.241  -0.356  -0.356  -0.335
160   L        -0.191  -0.191  -0.178  -0.037  -0.037  -0.015  -0.356  -0.356  -0.335
161   G         1.661   1.662   1.673   1.748   1.749   1.768   1.768   1.768   1.782
162   Y        -0.191  -0.191  -0.178  -0.011  -0.011   0.011  -0.356  -0.356  -0.335
163   S         1.661   1.662   1.673   1.143   1.144   1.164   1.768   1.768   1.782
164   S        -0.191  -0.191  -0.178  -0.615  -0.615  -0.593  -0.356  -0.356  -0.335
165   E        -0.191  -0.191  -0.178  -0.031  -0.031  -0.009  -0.356  -0.356  -0.335
166   P        -0.191  -0.191  -0.178  -0.084  -0.084  -0.062  -0.356  -0.356  -0.335
167   D        -0.191  -0.191  -0.178  -0.242  -0.242  -0.220  -0.356  -0.356  -0.335
168   P        -0.191  -0.191  -0.178  -0.031  -0.031  -0.009  -0.356  -0.356  -0.335
169   L        -0.191  -0.191  -0.178  -0.037  -0.037  -0.015  -0.356  -0.356  -0.335
170   F        -1.275  -1.274  -1.261  -0.866  -0.861  -0.843  -1.064  -1.063  -1.041
171   S        -1.275  -1.274  -1.261  -1.443  -1.431  -1.419  -1.064  -1.063  -1.041
172   P         1.661   1.662   1.673   1.843   1.844   1.863   1.768   1.768   1.782
173   C        -1.275  -1.274  -1.261  -0.725  -0.730  -0.702  -1.064  -1.063  -1.041
174   H         1.661   1.662   1.673   1.876   1.877   1.896   1.768   1.768   1.782
175   Q        -0.191  -0.191  -0.178  -0.057  -0.057  -0.035  -0.356  -0.356  -0.335
176   P        -0.191  -0.191  -0.178   0.090   0.090   0.112  -0.356  -0.356  -0.335
177   S        -0.191  -0.191  -0.178  -0.533  -0.533  -0.510  -0.356  -0.356  -0.335
178   F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
179   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
180   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
181   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
182   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
183   F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
184   S        -0.191  -0.191  -0.178  -0.568  -0.568  -0.546  -0.356  -0.356  -0.335
185   Y         1.661   1.662   1.673   1.962   1.963   1.982   1.768   1.768   1.782
186   S        -0.191  -0.191  -0.178  -0.489  -0.489  -0.466  -0.356  -0.356  -0.335
187   A        -0.191  -0.191  -0.178  -0.284  -0.284  -0.262  -0.356  -0.356  -0.335
188   D        -0.191  -0.191  -0.178  -0.419  -0.419  -0.397  -0.356  -0.356  -0.335
189   N        -0.191  -0.191  -0.178  -0.097  -0.097  -0.075  -0.356  -0.356  -0.335
190   E        -0.191  -0.191  -0.178  -0.309  -0.309  -0.287  -0.356  -0.356  -0.335
191   L         1.661   1.662   1.673   1.529   1.530   1.549   1.768   1.768   1.782
192   P         1.661   1.662   1.673   1.843   1.844   1.863   1.768   1.768   1.782
193   M        -1.275  -1.274  -1.261  -0.876  -0.881  -0.853  -1.064  -1.063  -1.041
194   E        -0.191  -0.191  -0.178  -0.554  -0.554  -0.532  -0.356  -0.356  -0.335
195   E         1.661   1.662   1.673   1.767   1.767   1.786   1.768   1.768   1.782
196   N        -0.191  -0.191  -0.178  -0.298  -0.298  -0.276  -0.356  -0.356  -0.335
197   H         1.661   1.662   1.673   1.924   1.925   1.944   1.768   1.768   1.782
198   N        -0.191  -0.191  -0.178  -0.173  -0.173  -0.151  -0.356  -0.356  -0.335
199   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
200   N        -0.191  -0.191  -0.178  -0.118  -0.118  -0.096  -0.356  -0.356  -0.335
201   N         1.661   1.662   1.673   1.767   1.767   1.786   1.768   1.768   1.782
202   F        -0.191  -0.191  -0.178  -0.186  -0.186  -0.164  -0.356  -0.356  -0.335
203   H        -0.191  -0.191  -0.178   0.061   0.062   0.083  -0.356  -0.356  -0.335
204   D        -0.191  -0.191  -0.178  -0.298  -0.298  -0.276  -0.356  -0.356  -0.335
205   S        -0.191  -0.191  -0.178  -0.592  -0.592  -0.570  -0.356  -0.356  -0.335
206   S        -0.191  -0.191  -0.178  -0.494  -0.494  -0.472  -0.356  -0.356  -0.335
207   E        -0.191  -0.191  -0.178   0.009   0.009   0.031  -0.356  -0.356  -0.335
208   S        -0.191  -0.191  -0.178  -0.646  -0.646  -0.623  -0.356  -0.356  -0.335
209   S        -0.191  -0.191  -0.178  -0.772  -0.772  -0.749  -0.356  -0.356  -0.335
210   I         1.661   1.662   1.673   1.720   1.720   1.739   1.768   1.768   1.782
211   F        -0.191  -0.191  -0.178  -0.554  -0.554  -0.532  -0.356  -0.356  -0.335
212   L        -0.191  -0.191  -0.178  -0.193  -0.193  -0.171  -0.356  -0.356  -0.335
213   P        -0.191  -0.191  -0.178  -0.472  -0.472  -0.450  -0.356  -0.356  -0.335
214   Q        -0.191  -0.191  -0.178   0.126   0.126   0.148  -0.356  -0.356  -0.335
215   I        -0.191  -0.191  -0.178  -0.221  -0.221  -0.199  -0.356  -0.356  -0.335
216   Q        -0.191  -0.191  -0.178  -0.071  -0.071  -0.049  -0.356  -0.356  -0.335
217   Q         1.661   1.662   1.673   1.933   1.934   1.953   1.768   1.768   1.782
218   S        -0.191  -0.191  -0.178  -0.569  -0.570  -0.547  -0.356  -0.356  -0.335
219   F        -0.191  -0.191  -0.178  -0.138  -0.138  -0.116  -0.356  -0.356  -0.335
220   F        -0.191  -0.191  -0.178  -0.138  -0.138  -0.116  -0.356  -0.356  -0.335
221   F        -0.191  -0.191  -0.178   0.016   0.016   0.037  -0.356  -0.356  -0.335
222   G        -0.191  -0.191  -0.178  -0.044  -0.044  -0.022  -0.356  -0.356  -0.335
223   D         1.661   1.662   1.673   1.498   1.498   1.518   1.768   1.768   1.782
224   N        -0.191  -0.191  -0.178  -0.173  -0.173  -0.151  -0.356  -0.356  -0.335
225   S        -0.191  -0.191  -0.178  -0.631  -0.631  -0.608  -0.356  -0.356  -0.335
226   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
227   S        -0.191  -0.191  -0.178  -0.772  -0.772  -0.749  -0.356  -0.356  -0.335
228   D         1.661   1.662   1.673   1.475   1.476   1.495   1.768   1.768   1.782
229   A        -1.275  -1.274  -1.261  -1.319  -1.329  -1.295  -1.064  -1.063  -1.041
230   N        -1.275  -1.274  -1.261  -1.313  -1.322  -1.290  -1.064  -1.063  -1.041
231   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
232   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
233   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
234   N        -0.040  -0.061  -0.081   0.131   0.100   0.066  -0.120  -0.152  -0.183
235   T        -1.275  -1.274  -1.261  -1.369  -1.377  -1.345  -1.064  -1.063  -1.041
236   D         1.661   1.662   1.673   1.475   1.476   1.495   1.768   1.768   1.782
237   F         1.661   1.662   1.673   1.802   1.804   1.822   1.768   1.768   1.782
238   W         1.661   1.662   1.673   2.035   2.036   2.054   1.768   1.768   1.782
239   K        -0.040  -0.061  -0.081  -0.002  -0.033  -0.062  -0.120  -0.152  -0.183
240   E        -0.040  -0.040  -0.095  -0.033  -0.033  -0.139  -0.120  -0.120  -0.205
241   V         1.661   1.662   1.673   1.786   1.783   1.806   1.768   1.768   1.782
242   N        -1.275  -1.274  -1.261  -1.226  -1.228  -1.203  -1.064  -1.063  -1.041
243   G        -1.275  -1.274  -1.261  -1.352  -1.362  -1.329  -1.064  -1.063  -1.041
244   T        -0.040  -0.040  -0.095  -0.187  -0.187  -0.310  -0.120  -0.120  -0.205
245   A        -1.275  -1.274  -1.261  -0.915  -0.913  -0.892  -1.064  -1.063  -1.041
246   E        -0.040  -0.018  -0.085   0.048   0.082  -0.022  -0.120  -0.086  -0.188
247   E         1.661   1.662   1.673   1.720   1.720   1.740   1.768   1.768   1.782
248   A         1.661   1.662   1.673   1.687   1.687   1.707   1.768   1.768   1.782
249   I        -1.275  -1.274  -1.261  -0.915  -0.910  -0.892  -1.064  -1.063  -1.041
250   C        -1.275  -1.274  -1.261  -0.881  -0.887  -0.858  -1.064  -1.063  -1.041
251   L        -1.275  -1.274  -1.261  -1.280  -1.278  -1.257  -1.064  -1.063  -1.041
252   -        -0.191  -0.191  -0.178  -0.305  -0.305  -0.283  -0.356  -0.356  -0.335
253   -        -0.191  -0.191  -0.178  -0.371  -0.371  -0.349  -0.356  -0.356  -0.335
254   -        -0.191  -0.191  -0.178  -0.267  -0.267  -0.245  -0.356  -0.356  -0.335
255   -        -0.191  -0.191  -0.178  -0.391  -0.391  -0.368  -0.356  -0.356  -0.335
256   -        -0.191  -0.191  -0.178  -0.410  -0.410  -0.388  -0.356  -0.356  -0.335
257   -        -0.191  -0.191  -0.178  -0.498  -0.498  -0.476  -0.356  -0.356  -0.335
258   -         1.661   1.662   1.673   1.648   1.649   1.668   1.768   1.768   1.782
259   -        -0.191  -0.191  -0.178  -0.410  -0.410  -0.388  -0.356  -0.356  -0.335
260   -        -0.191  -0.191  -0.178  -0.193  -0.193  -0.171  -0.356  -0.356  -0.335
261   -        -0.191  -0.191  -0.178  -0.681  -0.681  -0.658  -0.356  -0.356  -0.335
262   Q        -1.275  -1.274  -1.261  -0.984  -0.991  -0.961  -1.064  -1.063  -1.041
263   E        -0.040  -0.040  -0.095  -0.147  -0.146  -0.271  -0.120  -0.120  -0.205
264   T        -1.275  -1.274  -1.261  -1.110  -1.112  -1.087  -1.064  -1.063  -1.041
265   R        -0.040  -0.040  -0.095   0.220   0.221   0.123  -0.120  -0.120  -0.205
266   Q        -0.040  -0.040  -0.095   0.275   0.275   0.182  -0.120  -0.120  -0.205
267   R        -0.040  -0.018  -0.085   0.059   0.090   0.002  -0.120  -0.086  -0.188
268   K        -0.040  -0.018  -0.085  -0.440  -0.405  -0.502  -0.120  -0.086  -0.188
269   C        -1.275  -1.274  -1.261  -1.024  -1.023  -1.001  -1.064  -1.063  -1.041
270   S        -0.040  -0.040  -0.095  -0.372  -0.370  -0.439  -0.120  -0.120  -0.205
271   L        -0.040  -0.040  -0.095  -0.252  -0.251  -0.373  -0.120  -0.120  -0.205
272   V        -0.040  -0.061  -0.081  -0.084  -0.129  -0.179  -0.120  -0.152  -0.183
273   A        -1.275  -1.274  -1.261  -1.034  -1.032  -1.011  -1.064  -1.063  -1.041
274   L        -0.040  -0.018  -0.085   0.052   0.089  -0.026  -0.120  -0.086  -0.188
275   H        -0.040  -0.040  -0.095   0.120   0.118   0.008  -0.120  -0.120  -0.205
276   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
277   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
278   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
279   P        -0.040  -0.018  -0.085   0.282   0.314   0.213  -0.120  -0.086  -0.188
280   G        -1.275  -1.274  -1.261  -1.014  -1.013  -0.990  -1.064  -1.063  -1.041
281   D        -1.275  -1.274  -1.261  -1.064  -1.056  -1.041  -1.064  -1.063  -1.041
282   A        -0.040  -0.040  -0.095   0.063   0.064  -0.021  -0.120  -0.120  -0.205
283   T        -1.275  -1.274  -1.261  -1.105  -1.101  -1.082  -1.064  -1.063  -1.041
284   T        -1.275  -1.274  -1.261  -1.064  -1.064  -1.041  -1.064  -1.063  -1.041
285   S        -0.040  -0.061  -0.081  -0.301  -0.324  -0.342  -0.120  -0.152  -0.183
286   S        -1.275  -1.274  -1.261  -1.308  -1.294  -1.284  -1.064  -1.063  -1.041
287   N        -1.275  -1.274  -1.261  -0.876  -0.874  -0.853  -1.064  -1.063  -1.041
288   D        -1.275  -1.274  -1.261  -1.460  -1.465  -1.436  -1.064  -1.063  -1.041
289   T        -1.275  -1.274  -1.261  -1.536  -1.538  -1.513  -1.064  -1.063  -1.041
290   L        -1.275  -1.274  -1.261  -1.126  -1.125  -1.103  -1.064  -1.063  -1.041
291   G        -1.275  -1.274  -1.261  -1.352  -1.362  -1.329  -1.064  -1.063  -1.041
292   I        -1.275  -1.274  -1.261  -1.039  -1.043  -1.016  -1.064  -1.063  -1.041
293   E         1.661   1.662   1.673   1.720   1.720   1.740   1.768   1.768   1.782
294   D         1.661   1.662   1.673   1.475   1.476   1.495   1.768   1.768   1.782
295   F         1.661   1.662   1.673   1.802   1.804   1.822   1.768   1.768   1.782
296   I        -0.040  -0.061  -0.081   0.059   0.025  -0.013  -0.120  -0.152  -0.183
297   K        -0.040  -0.061  -0.081  -0.002  -0.033  -0.062  -0.120  -0.152  -0.183
298   D        -1.275  -1.274  -1.261  -1.105  -1.097  -1.082  -1.064  -1.063  -1.041
299   D        -0.040  -0.061  -0.081  -0.147  -0.177  -0.205  -0.120  -0.152  -0.183
300   I        -1.275  -1.274  -1.261  -1.189  -1.193  -1.166  -1.064  -1.063  -1.041
301   N        -1.275  -1.274  -1.261  -1.386  -1.386  -1.362  -1.064  -1.063  -1.041
302   S        -1.275  -1.274  -1.261  -1.483  -1.473  -1.460  -1.064  -1.063  -1.041
303   A        -1.275  -1.274  -1.261  -1.335  -1.330  -1.312  -1.064  -1.063  -1.041
304   E        -1.275  -1.274  -1.261  -1.079  -1.085  -1.056  -1.064  -1.063  -1.041
305   A        -1.275  -1.274  -1.261  -1.341  -1.336  -1.317  -1.064  -1.063  -1.041
306   M        -0.191  -0.191  -0.178   0.059   0.059   0.081  -0.356  -0.356  -0.335
307   E        -0.191  -0.191  -0.178  -0.259  -0.259  -0.237  -0.356  -0.356  -0.335
308   P         1.661   1.662   1.673   1.843   1.844   1.863   1.768   1.768   1.782
309   S        -0.191  -0.191  -0.178  -0.595  -0.595  -0.573  -0.356  -0.356  -0.335
310   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
311   S        -0.191  -0.191  -0.178  -0.646  -0.646  -0.623  -0.356  -0.356  -0.335
312   S         1.661   1.662   1.673   1.143   1.144   1.164   1.768   1.768   1.782
313   S        -0.191  -0.191  -0.178  -0.631  -0.631  -0.608  -0.356  -0.356  -0.335
314   P        -0.191  -0.191  -0.178   0.009   0.009   0.031  -0.356  -0.356  -0.335
315   S        -0.191  -0.191  -0.178  -0.569  -0.570  -0.547  -0.356  -0.356  -0.335
316   S         1.661   1.662   1.673   1.143   1.144   1.164   1.768   1.768   1.782
317   S        -0.191  -0.191  -0.178  -0.772  -0.772  -0.749  -0.356  -0.356  -0.335
318   L        -0.191  -0.191  -0.178  -0.152  -0.152  -0.130  -0.356  -0.356  -0.335
319   L        -0.191  -0.191  -0.178  -0.077  -0.077  -0.055  -0.356  -0.356  -0.335
320   D        -0.191  -0.191  -0.178  -0.772  -0.772  -0.749  -0.356  -0.356  -0.335
321   N        -0.191  -0.191  -0.178   0.016   0.016   0.037  -0.356  -0.356  -0.335
322   L        -0.191  -0.191  -0.178  -0.193  -0.193  -0.171  -0.356  -0.356  -0.335
323   D        -0.191  -0.191  -0.178  -0.138  -0.138  -0.116  -0.356  -0.356  -0.335
324   Y        -0.040  -0.061  -0.081   0.435   0.403   0.371  -0.120  -0.152  -0.183
325   N        -1.275  -1.274  -1.261  -0.934  -0.934  -0.911  -1.064  -1.063  -1.041
326   I        -0.040  -0.061  -0.081   0.139   0.106   0.076  -0.120  -0.152  -0.183
327   K         1.661   1.662   1.673   1.611   1.611   1.631   1.768   1.768   1.782
328   L        -0.040  -0.040  -0.095  -0.072  -0.073  -0.164  -0.120  -0.120  -0.205
329   L         1.661   1.662   1.673   1.611   1.611   1.631   1.768   1.768   1.782
330   C        -0.040  -0.040  -0.095   0.131   0.132  -0.002  -0.120  -0.120  -0.205
331   Y        -1.275  -1.274  -1.261  -0.866  -0.873  -0.843  -1.064  -1.063  -1.041
332   R         1.661   1.662   1.673   1.892   1.893   1.911   1.768   1.768   1.782
333   D         1.661   1.662   1.673   1.475   1.476   1.495   1.768   1.768   1.782
334   N        -1.275  -1.274  -1.261  -1.335  -1.344  -1.312  -1.064  -1.063  -1.041
335   E        -1.275  -1.274  -1.261  -1.074  -1.076  -1.051  -1.064  -1.063  -1.041
336   G         1.661   1.662   1.673   1.745   1.745   1.765   1.768   1.768   1.782
337   K         1.661   1.662   1.673   1.611   1.611   1.631   1.768   1.768   1.782
338   F        -0.040  -0.040  -0.095   0.105   0.105   0.006  -0.120  -0.120  -0.205
339   T        -0.040  -0.040  -0.095   0.025   0.024  -0.064  -0.120  -0.120  -0.205
340   L         1.661   1.662   1.673   1.611   1.611   1.631   1.768   1.768   1.782
341   K        -0.191  -0.191  -0.178  -0.355  -0.355  -0.333  -0.356  -0.356  -0.335
342   K        -0.191  -0.191  -0.178  -0.084  -0.084  -0.062  -0.356  -0.356  -0.335
343   R        -0.191  -0.191  -0.178   0.068   0.068   0.090  -0.356  -0.356  -0.335
344   K        -0.191  -0.191  -0.178  -0.118  -0.118  -0.096  -0.356  -0.356  -0.335
345   F        -0.191  -0.191  -0.178  -0.554  -0.554  -0.532  -0.356  -0.356  -0.335
346   L        -0.191  -0.191  -0.178  -0.654  -0.654  -0.631  -0.356  -0.356  -0.335
347   K        -0.040  -0.040  -0.095   0.010   0.007  -0.070  -0.120  -0.120  -0.205
348   N        -1.275  -1.274  -1.261  -1.184  -1.184  -1.160  -1.064  -1.063  -1.041
349   S        -0.040  -0.061  -0.081  -0.406  -0.433  -0.459  -0.120  -0.152  -0.183
350   L        -1.275  -1.274  -1.261  -0.999  -0.997  -0.975  -1.064  -1.063  -1.041
351   R        -0.040  -0.040  -0.095   0.220   0.221   0.123  -0.120  -0.120  -0.205
352   S         1.661   1.662   1.673   1.219   1.222   1.239   1.768   1.768   1.782
353   S        -1.275  -1.274  -1.261  -1.443  -1.432  -1.419  -1.064  -1.063  -1.041
354   S         1.661   1.662   1.673   1.143   1.144   1.164   1.768   1.768   1.782
355   A        -0.191  -0.191  -0.178  -0.221  -0.221  -0.199  -0.356  -0.356  -0.335
356   I        -0.191  -0.191  -0.178  -0.592  -0.592  -0.570  -0.356  -0.356  -0.335
357   S        -0.191  -0.191  -0.178  -0.554  -0.554  -0.532  -0.356  -0.356  -0.335
358   K        -0.191  -0.191  -0.178  -0.615  -0.615  -0.593  -0.356  -0.356  -0.335
359   K        -0.191  -0.191  -0.178  -0.159  -0.159  -0.137  -0.356  -0.356  -0.335
360   W        -0.191  -0.191  -0.178   0.094   0.094   0.116  -0.356  -0.356  -0.335
361   K        -0.191  -0.191  -0.178  -0.159  -0.159  -0.137  -0.356  -0.356  -0.335
362   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
363   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
364   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
365   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
366   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
367   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
368   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
369   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
370   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
371   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
372   P        -0.040  -0.018  -0.085   0.037   0.067  -0.024  -0.120  -0.086  -0.188
373   L        -1.275  -1.274  -1.261  -1.386  -1.379  -1.362  -1.064  -1.063  -1.041
374   S        -1.275  -1.274  -1.261  -1.397  -1.386  -1.373  -1.064  -1.063  -1.041
375   K        -0.040  -0.061  -0.081   0.010  -0.024  -0.049  -0.120  -0.152  -0.183
376   R        -0.040  -0.061  -0.081   0.187   0.151   0.111  -0.120  -0.152  -0.183
377   D        -0.040  -0.018  -0.085  -0.135  -0.097  -0.217  -0.120  -0.086  -0.188
378   K        -1.275  -1.274  -1.261  -1.386  -1.379  -1.362  -1.064  -1.063  -1.041
379   L        -0.040  -0.018  -0.085  -0.072  -0.037  -0.146  -0.120  -0.086  -0.188
380   L        -1.275  -1.274  -1.261  -1.116  -1.115  -1.092  -1.064  -1.063  -1.041
381   K        -0.040  -0.061  -0.081  -0.002  -0.033  -0.062  -0.120  -0.152  -0.183
382   R        -0.040  -0.018  -0.085   0.059   0.089   0.002  -0.120  -0.086  -0.188
383   A        -1.275  -1.274  -1.261  -0.994  -0.992  -0.970  -1.064  -1.063  -1.041
384   I        -1.275  -1.274  -1.261  -1.391  -1.391  -1.368  -1.064  -1.063  -1.041
385   R         1.661   1.662   1.673   1.892   1.893   1.911   1.768   1.768   1.782
386   R        -0.040  -0.040  -0.095   0.017   0.019  -0.112  -0.120  -0.120  -0.205
387   K         1.661   1.662   1.673   1.611   1.611   1.631   1.768   1.768   1.782
388   S        -0.040  -0.040  -0.095  -0.343  -0.340  -0.405  -0.120  -0.120  -0.205
389   G         1.661   1.662   1.673   1.745   1.745   1.765   1.768   1.768   1.782
390   V        -0.040  -0.040  -0.095   0.282   0.278   0.213  -0.120  -0.120  -0.205
391   C         1.661   1.662   1.673   2.011   2.012   2.031   1.768   1.768   1.782
392   Q        -1.275  -1.274  -1.261  -0.934  -0.938  -0.911  -1.064  -1.063  -1.041
393   T        -0.040  -0.018  -0.085   0.275   0.312   0.194  -0.120  -0.086  -0.188
394   L        -1.275  -1.274  -1.261  -1.039  -1.037  -1.016  -1.064  -1.063  -1.041
395   S         1.661   1.662   1.673   1.219   1.222   1.239   1.768   1.768   1.782
396   A        -0.040  -0.018  -0.085   0.025   0.059  -0.046  -0.120  -0.086  -0.188
397   G         1.661   1.662   1.673   1.745   1.745   1.765   1.768   1.768   1.782
398   F        -0.040  -0.018  -0.085   0.146   0.181   0.079  -0.120  -0.086  -0.188
399   G         1.661   1.662   1.673   1.745   1.745   1.765   1.768   1.768   1.782
400   I         1.661   1.662   1.673   1.753   1.755   1.773   1.768   1.768   1.782
401   G        -0.040  -0.061  -0.081   0.120   0.088   0.056  -0.120  -0.152  -0.183
402   E         1.661   1.662   1.673   1.720   1.720   1.740   1.768   1.768   1.782
403   F         1.661   1.662   1.673   1.802   1.804   1.822   1.768   1.768   1.782
404   M         1.661   1.662   1.673   1.956   1.956   1.975   1.768   1.768   1.782
405   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
406   L         1.661   1.662   1.673   1.611   1.611   1.631   1.768   1.768   1.782
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P53249
Output conservation file - output/P53249
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
