1     M         0.946   0.953   0.977   1.256   1.260   1.280   0.986   0.994   1.022
2     S         0.946   0.953   0.977   0.923   0.935   0.972   0.986   0.994   1.022
3     E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    S        -0.502  -0.541  -0.506  -0.390  -0.467  -0.442  -0.687  -0.746  -0.690
15    S         0.946   0.953   0.977   0.923   0.935   0.972   0.986   0.994   1.022
16    L         0.946   0.953   0.977   0.784   0.792   0.844   0.986   0.994   1.022
17    E         0.946   0.953   0.977   0.895   0.906   0.947   0.986   0.994   1.022
18    Q         0.946   0.953   0.977   1.191   1.200   1.220   0.986   0.994   1.022
19    L         0.946   0.953   0.977   0.784   0.792   0.844   0.986   0.994   1.022
20    K         0.946   0.953   0.977   0.774   0.781   0.835   0.986   0.994   1.022
21    K        -0.334  -0.421  -0.477  -0.616  -0.749  -0.845  -0.426  -0.556  -0.643
22    A        -0.631  -0.622  -0.525  -0.964  -0.943  -0.772  -0.896  -0.877  -0.721
23    G         0.946   0.953   0.977   1.045   1.052   1.085   0.986   0.994   1.022
24    T         0.946   0.953   0.977   0.995   1.005   1.040   0.986   0.994   1.022
25    H        -1.420  -1.415  -1.382  -1.190  -1.174  -1.115  -1.367  -1.355  -1.277
26    V         0.946   0.953   0.977   1.000   1.004   1.044   0.986   0.994   1.022
27    V         0.946   0.953   0.977   1.000   1.004   1.044   0.986   0.994   1.022
28    A        -2.209  -2.185  -2.029  -2.051  -2.030  -1.773  -1.837  -1.803  -1.593
29    D         0.946   0.953   0.977   0.977   0.987   1.023   0.986   0.994   1.022
30    S        -0.631  -0.614  -0.522  -0.790  -0.761  -0.606  -0.896  -0.863  -0.716
31    G         0.946   0.953   0.977   1.045   1.052   1.085   0.986   0.994   1.022
32    D        -0.334  -0.239  -0.459  -0.288  -0.144  -0.506  -0.426  -0.283  -0.615
33    F         0.946   0.953   0.977   1.090   1.099   1.126   0.986   0.994   1.022
34    E        -0.334  -0.329  -0.468  -0.436  -0.423  -0.698  -0.426  -0.416  -0.629
35    A        -1.420  -1.468  -1.389  -1.509  -1.600  -1.475  -1.367  -1.414  -1.285
36    I        -0.334  -0.329  -0.468  -0.226  -0.219  -0.386  -0.426  -0.416  -0.629
37    S        -0.334  -0.421  -0.477  -0.566  -0.685  -0.763  -0.426  -0.556  -0.643
38    K         0.946   0.953   0.977   0.774   0.781   0.835   0.986   0.994   1.022
39    Y         0.946   0.953   0.977   1.147   1.152   1.180   0.986   0.994   1.022
40    E        -0.334  -0.421  -0.477  -0.486  -0.626  -0.704  -0.426  -0.556  -0.643
41    P         0.946   0.953   0.977   1.160   1.168   1.192   0.986   0.994   1.022
42    Q         0.946   0.953   0.977   1.191   1.200   1.220   0.986   0.994   1.022
43    D         0.946   0.953   0.977   0.977   0.987   1.023   0.986   0.994   1.022
44    S        -0.334  -0.421  -0.477  -0.566  -0.685  -0.763  -0.426  -0.556  -0.643
45    T         0.946   0.953   0.977   0.995   1.005   1.040   0.986   0.994   1.022
46    T         0.946   0.953   0.977   0.995   1.005   1.040   0.986   0.994   1.022
47    N         0.946   0.953   0.977   1.143   1.149   1.175   0.986   0.994   1.022
48    P         0.946   0.953   0.977   1.160   1.168   1.192   0.986   0.994   1.022
49    S         0.946   0.953   0.977   0.923   0.935   0.972   0.986   0.994   1.022
50    L         0.946   0.953   0.977   0.784   0.792   0.844   0.986   0.994   1.022
51    I         0.946   0.953   0.977   0.918   0.929   0.968   0.986   0.994   1.022
52    L         0.946   0.953   0.977   0.784   0.792   0.844   0.986   0.994   1.022
53    A         0.946   0.953   0.977   0.684   0.708   0.752   0.986   0.994   1.022
54    A         0.946   0.953   0.977   0.684   0.708   0.752   0.986   0.994   1.022
55    S         0.946   0.953   0.977   0.923   0.935   0.972   0.986   0.994   1.022
56    K         0.946   0.953   0.977   0.774   0.781   0.835   0.986   0.994   1.022
57    L        -0.334  -0.421  -0.477  -0.523  -0.673  -0.765  -0.426  -0.556  -0.643
58    E        -0.334  -0.421  -0.477  -0.111  -0.257  -0.393  -0.426  -0.556  -0.643
59    K        -1.420  -1.448  -1.386  -1.406  -1.470  -1.338  -1.367  -1.392  -1.282
60    Y         0.946   0.953   0.977   1.147   1.152   1.180   0.986   0.994   1.022
61    A        -0.334  -0.329  -0.468  -0.523  -0.503  -0.683  -0.426  -0.416  -0.629
62    R        -1.420  -1.415  -1.382  -1.595  -1.549  -1.481  -1.367  -1.355  -1.277
63    F        -0.334  -0.421  -0.477  -0.411  -0.537  -0.591  -0.426  -0.556  -0.643
64    I        -1.420  -1.393  -1.378  -1.468  -1.426  -1.405  -1.367  -1.325  -1.273
65    D         0.946   0.953   0.977   0.977   0.987   1.023   0.986   0.994   1.022
66    A        -0.334  -0.239  -0.459  -0.575  -0.421  -0.749  -0.426  -0.283  -0.615
67    A         0.946   0.953   0.977   0.684   0.708   0.752   0.986   0.994   1.022
68    V        -0.334  -0.329  -0.468  -0.258  -0.256  -0.493  -0.426  -0.416  -0.629
69    E        -2.209  -2.185  -2.029  -2.299  -2.254  -2.002  -1.837  -1.803  -1.593
70    Y        -1.420  -1.356  -1.376  -1.151  -1.056  -1.105  -1.367  -1.282  -1.270
71    G        -0.334  -0.421  -0.477  -0.523  -0.637  -0.695  -0.426  -0.556  -0.643
72    R        -0.334  -0.421  -0.477  -0.389  -0.510  -0.548  -0.426  -0.556  -0.643
73    K        -1.420  -1.331  -1.371  -1.644  -1.498  -1.552  -1.367  -1.252  -1.265
74    H        -1.420  -1.468  -1.389  -1.356  -1.402  -1.239  -1.367  -1.414  -1.285
75    G        -1.420  -1.356  -1.376  -1.229  -1.126  -1.165  -1.367  -1.282  -1.270
76    K        -1.420  -1.415  -1.382  -1.394  -1.406  -1.368  -1.367  -1.355  -1.277
77    T        -1.420  -1.415  -1.382  -1.382  -1.373  -1.313  -1.367  -1.355  -1.277
78    D        -1.420  -1.448  -1.386  -1.211  -1.263  -1.199  -1.367  -1.392  -1.282
79    H        -2.209  -2.185  -2.029  -1.952  -1.886  -1.683  -1.837  -1.803  -1.593
80    E        -0.334  -0.294  -0.464  -0.359  -0.296  -0.568  -0.426  -0.363  -0.622
81    K        -0.631  -0.614  -0.522  -0.750  -0.748  -0.582  -0.896  -0.863  -0.716
82    I        -0.631  -0.618  -0.524  -0.790  -0.774  -0.609  -0.896  -0.871  -0.719
83    E        -1.420  -1.356  -1.376  -1.341  -1.253  -1.249  -1.367  -1.282  -1.270
84    N        -1.420  -1.468  -1.389  -1.446  -1.504  -1.397  -1.367  -1.414  -1.285
85    A         0.946   0.953   0.977   0.684   0.708   0.752   0.986   0.994   1.022
86    M        -1.420  -1.448  -1.386  -1.335  -1.356  -1.217  -1.367  -1.392  -1.282
87    D         0.946   0.953   0.977   0.977   0.987   1.023   0.986   0.994   1.022
88    K        -2.209  -2.185  -2.029  -1.841  -1.848  -1.580  -1.837  -1.803  -1.593
89    I        -0.334  -0.421  -0.477  -0.469  -0.607  -0.684  -0.426  -0.556  -0.643
90    L         0.946   0.953   0.977   0.784   0.792   0.844   0.986   0.994   1.022
91    V        -0.631  -0.614  -0.522  -0.790  -0.757  -0.600  -0.896  -0.863  -0.716
92    E        -0.334  -0.329  -0.468  -0.270  -0.261  -0.438  -0.426  -0.416  -0.629
93    F         0.946   0.953   0.977   1.090   1.099   1.126   0.986   0.994   1.022
94    G         0.946   0.953   0.977   1.045   1.052   1.085   0.986   0.994   1.022
95    T        -1.420  -1.356  -1.376  -1.438  -1.331  -1.390  -1.367  -1.282  -1.270
96    Q        -1.420  -1.415  -1.382  -1.458  -1.431  -1.353  -1.367  -1.355  -1.277
97    I         0.946   0.953   0.977   0.918   0.929   0.968   0.986   0.994   1.022
98    L         0.946   0.953   0.977   0.784   0.792   0.844   0.986   0.994   1.022
99    K        -1.420  -1.393  -1.378  -1.692  -1.637  -1.619  -1.367  -1.325  -1.273
100   V        -0.334  -0.421  -0.477  -0.311  -0.446  -0.533  -0.426  -0.556  -0.643
101   V         0.946   0.953   0.977   1.000   1.004   1.044   0.986   0.994   1.022
102   P         0.946   0.953   0.977   1.160   1.168   1.192   0.986   0.994   1.022
103   G         0.946   0.953   0.977   1.045   1.052   1.085   0.986   0.994   1.022
104   R        -0.334  -0.329  -0.468  -0.126  -0.124  -0.415  -0.426  -0.416  -0.629
105   V         0.946   0.953   0.977   1.000   1.004   1.044   0.986   0.994   1.022
106   S         0.946   0.953   0.977   0.923   0.935   0.972   0.986   0.994   1.022
107   T         0.946   0.953   0.977   0.995   1.005   1.040   0.986   0.994   1.022
108   E         0.946   0.953   0.977   0.895   0.906   0.947   0.986   0.994   1.022
109   V         0.946   0.953   0.977   1.000   1.004   1.044   0.986   0.994   1.022
110   D         0.946   0.953   0.977   0.977   0.987   1.023   0.986   0.994   1.022
111   A         0.946   0.953   0.977   0.684   0.708   0.752   0.986   0.994   1.022
112   R        -0.334  -0.329  -0.468  -0.153  -0.146  -0.458  -0.426  -0.416  -0.629
113   L        -0.334  -0.294  -0.464  -0.392  -0.339  -0.543  -0.426  -0.363  -0.622
114   S         0.946   0.953   0.977   0.923   0.935   0.972   0.986   0.994   1.022
115   F         0.946   0.953   0.977   1.090   1.099   1.126   0.986   0.994   1.022
116   D         0.946   0.953   0.977   0.977   0.987   1.023   0.986   0.994   1.022
117   K        -0.631  -0.622  -0.525  -0.898  -0.888  -0.710  -0.896  -0.877  -0.721
118   K        -1.420  -1.331  -1.371  -1.422  -1.300  -1.302  -1.367  -1.252  -1.265
119   A        -0.334  -0.294  -0.464  -0.541  -0.469  -0.703  -0.426  -0.363  -0.622
120   T        -0.334  -0.329  -0.468  -0.261  -0.253  -0.495  -0.426  -0.416  -0.629
121   V        -0.631  -0.614  -0.522  -0.790  -0.757  -0.600  -0.896  -0.863  -0.716
122   K        -1.420  -1.393  -1.378  -1.557  -1.514  -1.462  -1.367  -1.325  -1.273
123   K         0.946   0.953   0.977   0.774   0.781   0.835   0.986   0.994   1.022
124   A         0.946   0.953   0.977   0.684   0.708   0.752   0.986   0.994   1.022
125   L        -0.334  -0.294  -0.464  -0.380  -0.327  -0.525  -0.426  -0.363  -0.622
126   H        -0.334  -0.239  -0.459   0.084   0.211  -0.131  -0.426  -0.283  -0.615
127   I        -0.631  -0.614  -0.522  -0.950  -0.909  -0.745  -0.896  -0.863  -0.716
128   I         0.946   0.953   0.977   0.918   0.929   0.968   0.986   0.994   1.022
129   K        -0.334  -0.239  -0.459  -0.459  -0.324  -0.632  -0.426  -0.283  -0.615
130   L         0.946   0.953   0.977   0.784   0.792   0.844   0.986   0.994   1.022
131   Y         0.946   0.953   0.977   1.147   1.152   1.180   0.986   0.994   1.022
132   K        -0.631  -0.622  -0.525  -0.974  -0.962  -0.780  -0.896  -0.877  -0.721
133   D        -0.334  -0.421  -0.477  -0.547  -0.664  -0.732  -0.426  -0.556  -0.643
134   A        -1.420  -1.415  -1.382  -1.635  -1.635  -1.603  -1.367  -1.355  -1.277
135   G         0.946   0.953   0.977   1.045   1.052   1.085   0.986   0.994   1.022
136   V        -0.334  -0.421  -0.477  -0.311  -0.446  -0.533  -0.426  -0.556  -0.643
137   P        -1.420  -1.448  -1.386  -1.281  -1.310  -1.200  -1.367  -1.392  -1.282
138   K        -1.420  -1.331  -1.371  -1.450  -1.324  -1.333  -1.367  -1.252  -1.265
139   E        -0.631  -0.618  -0.524  -0.823  -0.803  -0.639  -0.896  -0.871  -0.719
140   R         0.946   0.953   0.977   1.182   1.188   1.212   0.986   0.994   1.022
141   V        -0.631  -0.618  -0.524  -0.790  -0.767  -0.605  -0.896  -0.871  -0.719
142   L         0.946   0.953   0.977   0.784   0.792   0.844   0.986   0.994   1.022
143   I         0.946   0.953   0.977   0.918   0.929   0.968   0.986   0.994   1.022
144   K         0.946   0.953   0.977   0.774   0.781   0.835   0.986   0.994   1.022
145   I         0.946   0.953   0.977   0.918   0.929   0.968   0.986   0.994   1.022
146   A         0.946   0.953   0.977   0.684   0.708   0.752   0.986   0.994   1.022
147   S         0.946   0.953   0.977   0.923   0.935   0.972   0.986   0.994   1.022
148   T         0.946   0.953   0.977   0.995   1.005   1.040   0.986   0.994   1.022
149   W        -0.631  -0.614  -0.522  -0.397  -0.361  -0.235  -0.896  -0.863  -0.716
150   E         0.946   0.953   0.977   0.895   0.906   0.947   0.986   0.994   1.022
151   G         0.946   0.953   0.977   1.045   1.052   1.085   0.986   0.994   1.022
152   I         0.946   0.953   0.977   0.918   0.929   0.968   0.986   0.994   1.022
153   Q        -0.334  -0.329  -0.468  -0.118  -0.112  -0.408  -0.426  -0.416  -0.629
154   A         0.946   0.953   0.977   0.684   0.708   0.752   0.986   0.994   1.022
155   A         0.946   0.953   0.977   0.684   0.708   0.752   0.986   0.994   1.022
156   R        -1.420  -1.468  -1.389  -1.462  -1.514  -1.363  -1.367  -1.414  -1.285
157   E        -1.420  -1.393  -1.378  -1.345  -1.305  -1.256  -1.367  -1.325  -1.273
158   L         0.946   0.953   0.977   0.784   0.792   0.844   0.986   0.994   1.022
159   E        -0.334  -0.329  -0.468  -0.270  -0.261  -0.438  -0.426  -0.416  -0.629
160   V        -1.554  -1.537  -1.405  -1.432  -1.404  -1.202  -1.524  -1.494  -1.302
161   K        -1.420  -1.393  -1.378  -1.557  -1.514  -1.462  -1.367  -1.325  -1.273
162   H        -0.334  -0.294  -0.464  -0.006   0.052  -0.278  -0.426  -0.363  -0.622
163   G         0.946   0.953   0.977   1.045   1.052   1.085   0.986   0.994   1.022
164   I         0.946   0.953   0.977   0.918   0.929   0.968   0.986   0.994   1.022
165   H        -0.334  -0.329  -0.468   0.069   0.070  -0.170  -0.426  -0.416  -0.629
166   C         0.946   0.953   0.977   1.295   1.303   1.316   0.986   0.994   1.022
167   N         0.946   0.953   0.977   1.143   1.149   1.175   0.986   0.994   1.022
168   M        -0.334  -0.421  -0.477  -0.354  -0.470  -0.501  -0.426  -0.556  -0.643
169   T         0.946   0.953   0.977   0.995   1.005   1.040   0.986   0.994   1.022
170   L         0.946   0.953   0.977   0.784   0.792   0.844   0.986   0.994   1.022
171   L        -0.334  -0.329  -0.468  -0.354  -0.349  -0.491  -0.426  -0.416  -0.629
172   F         0.946   0.953   0.977   1.090   1.099   1.126   0.986   0.994   1.022
173   S         0.946   0.953   0.977   0.923   0.935   0.972   0.986   0.994   1.022
174   F        -0.334  -0.329  -0.468  -0.213  -0.207  -0.487  -0.426  -0.416  -0.629
175   T        -0.631  -0.614  -0.522  -0.734  -0.707  -0.551  -0.896  -0.863  -0.716
176   Q         0.946   0.953   0.977   1.191   1.200   1.220   0.986   0.994   1.022
177   A         0.946   0.953   0.977   0.684   0.708   0.752   0.986   0.994   1.022
178   V        -0.334  -0.329  -0.468  -0.258  -0.256  -0.493  -0.426  -0.416  -0.629
179   A         0.946   0.953   0.977   0.684   0.708   0.752   0.986   0.994   1.022
180   C        -0.334  -0.329  -0.468  -0.043  -0.034  -0.365  -0.426  -0.416  -0.629
181   A         0.946   0.953   0.977   0.684   0.708   0.752   0.986   0.994   1.022
182   E         0.946   0.953   0.977   0.895   0.906   0.947   0.986   0.994   1.022
183   A         0.946   0.953   0.977   0.684   0.708   0.752   0.986   0.994   1.022
184   N        -1.420  -1.356  -1.376  -1.256  -1.143  -1.224  -1.367  -1.282  -1.270
185   V        -0.334  -0.329  -0.468  -0.332  -0.326  -0.610  -0.426  -0.416  -0.629
186   T        -0.334  -0.329  -0.468  -0.208  -0.200  -0.411  -0.426  -0.416  -0.629
187   L         0.946   0.953   0.977   0.784   0.792   0.844   0.986   0.994   1.022
188   I         0.946   0.953   0.977   0.918   0.929   0.968   0.986   0.994   1.022
189   S         0.946   0.953   0.977   0.923   0.935   0.972   0.986   0.994   1.022
190   P         0.946   0.953   0.977   1.160   1.168   1.192   0.986   0.994   1.022
191   F         0.946   0.953   0.977   1.090   1.099   1.126   0.986   0.994   1.022
192   V         0.946   0.953   0.977   1.000   1.004   1.044   0.986   0.994   1.022
193   G         0.946   0.953   0.977   1.045   1.052   1.085   0.986   0.994   1.022
194   R         0.946   0.953   0.977   1.182   1.188   1.212   0.986   0.994   1.022
195   I         0.946   0.953   0.977   0.918   0.929   0.968   0.986   0.994   1.022
196   M        -0.334  -0.421  -0.477  -0.354  -0.470  -0.501  -0.426  -0.556  -0.643
197   D         0.946   0.953   0.977   0.977   0.987   1.023   0.986   0.994   1.022
198   F        -0.631  -0.618  -0.524  -0.436  -0.426  -0.286  -0.896  -0.871  -0.719
199   Y        -1.420  -1.356  -1.376  -1.032  -0.950  -0.969  -1.367  -1.282  -1.270
200   K         0.946   0.953   0.977   0.774   0.781   0.835   0.986   0.994   1.022
201   A         0.946   0.953   0.977   0.684   0.708   0.752   0.986   0.994   1.022
202   L        -2.209  -2.185  -2.029  -2.271  -2.222  -1.977  -1.837  -1.803  -1.593
203   S        -1.420  -1.448  -1.386  -1.279  -1.333  -1.223  -1.367  -1.392  -1.282
204   G        -0.334  -0.294  -0.464  -0.143  -0.090  -0.338  -0.426  -0.363  -0.622
205   K        -0.334  -0.294  -0.464  -0.389  -0.337  -0.532  -0.426  -0.363  -0.622
206   D        -1.420  -1.356  -1.376  -1.264  -1.166  -1.184  -1.367  -1.282  -1.270
207   Y         0.946   0.953   0.977   1.147   1.152   1.180   0.986   0.994   1.022
208   T        -1.420  -1.356  -1.376  -1.350  -1.247  -1.289  -1.367  -1.282  -1.270
209   A        -0.334  -0.329  -0.468  -0.616  -0.596  -0.829  -0.426  -0.416  -0.629
210   E        -1.420  -1.331  -1.371  -1.444  -1.289  -1.360  -1.367  -1.252  -1.265
211   T        -0.334  -0.421  -0.477  -0.335  -0.468  -0.553  -0.426  -0.556  -0.643
212   D         0.946   0.953   0.977   0.977   0.987   1.023   0.986   0.994   1.022
213   P         0.946   0.953   0.977   1.160   1.168   1.192   0.986   0.994   1.022
214   G         0.946   0.953   0.977   1.045   1.052   1.085   0.986   0.994   1.022
215   V         0.946   0.953   0.977   1.000   1.004   1.044   0.986   0.994   1.022
216   L        -2.209  -2.185  -2.029  -2.355  -2.328  -2.054  -1.837  -1.803  -1.593
217   S         0.946   0.953   0.977   0.923   0.935   0.972   0.986   0.994   1.022
218   V         0.946   0.953   0.977   1.000   1.004   1.044   0.986   0.994   1.022
219   K        -0.334  -0.294  -0.464  -0.477  -0.418  -0.668  -0.426  -0.363  -0.622
220   K        -1.420  -1.468  -1.389  -1.277  -1.384  -1.278  -1.367  -1.414  -1.285
221   I         0.946   0.953   0.977   0.918   0.929   0.968   0.986   0.994   1.022
222   Y        -0.334  -0.421  -0.477  -0.099  -0.229  -0.322  -0.426  -0.556  -0.643
223   S        -1.420  -1.415  -1.382  -1.224  -1.228  -1.200  -1.367  -1.355  -1.277
224   Y         0.946   0.953   0.977   1.147   1.152   1.180   0.986   0.994   1.022
225   Y         0.946   0.953   0.977   1.147   1.152   1.180   0.986   0.994   1.022
226   K         0.946   0.953   0.977   0.774   0.781   0.835   0.986   0.994   1.022
227   R        -0.334  -0.421  -0.477  -0.389  -0.510  -0.548  -0.426  -0.556  -0.643
228   H        -0.334  -0.421  -0.477  -0.060  -0.182  -0.260  -0.426  -0.556  -0.643
229   G        -0.334  -0.239  -0.459  -0.196  -0.059  -0.411  -0.426  -0.283  -0.615
230   Y         0.946   0.953   0.977   1.147   1.152   1.180   0.986   0.994   1.022
231   A        -0.334  -0.421  -0.477  -0.556  -0.706  -0.819  -0.426  -0.556  -0.643
232   T         0.946   0.953   0.977   0.995   1.005   1.040   0.986   0.994   1.022
233   E        -0.334  -0.421  -0.477  -0.345  -0.485  -0.588  -0.426  -0.556  -0.643
234   V         0.946   0.953   0.977   1.000   1.004   1.044   0.986   0.994   1.022
235   M         0.946   0.953   0.977   1.256   1.260   1.280   0.986   0.994   1.022
236   A        -0.334  -0.421  -0.477  -0.288  -0.443  -0.592  -0.426  -0.556  -0.643
237   A         0.946   0.953   0.977   0.684   0.708   0.752   0.986   0.994   1.022
238   S         0.946   0.953   0.977   0.923   0.935   0.972   0.986   0.994   1.022
239   F         0.946   0.953   0.977   1.090   1.099   1.126   0.986   0.994   1.022
240   R         0.946   0.953   0.977   1.182   1.188   1.212   0.986   0.994   1.022
241   N         0.946   0.953   0.977   1.143   1.149   1.175   0.986   0.994   1.022
242   L        -2.209  -2.185  -2.029  -2.171  -2.157  -1.885  -1.837  -1.803  -1.593
243   D        -0.334  -0.421  -0.477  -0.196  -0.337  -0.443  -0.426  -0.556  -0.643
244   E         0.946   0.953   0.977   0.895   0.906   0.947   0.986   0.994   1.022
245   L        -0.334  -0.421  -0.477  -0.381  -0.529  -0.646  -0.426  -0.556  -0.643
246   K        -0.334  -0.329  -0.468  -0.453  -0.447  -0.637  -0.426  -0.416  -0.629
247   A        -0.334  -0.421  -0.477  -0.436  -0.585  -0.717  -0.426  -0.556  -0.643
248   L         0.946   0.953   0.977   0.784   0.792   0.844   0.986   0.994   1.022
249   A         0.946   0.953   0.977   0.684   0.708   0.752   0.986   0.994   1.022
250   G         0.946   0.953   0.977   1.045   1.052   1.085   0.986   0.994   1.022
251   I        -1.420  -1.448  -1.386  -1.087  -1.152  -1.099  -1.367  -1.392  -1.282
252   D         0.946   0.953   0.977   0.977   0.987   1.023   0.986   0.994   1.022
253   N        -1.420  -1.468  -1.389  -1.107  -1.178  -1.056  -1.367  -1.414  -1.285
254   M        -0.334  -0.421  -0.477  -0.354  -0.470  -0.501  -0.426  -0.556  -0.643
255   T         0.946   0.953   0.977   0.995   1.005   1.040   0.986   0.994   1.022
256   L        -0.334  -0.421  -0.477  -0.381  -0.529  -0.646  -0.426  -0.556  -0.643
257   P        -0.334  -0.421  -0.477  -0.254  -0.374  -0.444  -0.426  -0.556  -0.643
258   L        -0.334  -0.421  -0.477  -0.145  -0.300  -0.448  -0.426  -0.556  -0.643
259   N        -1.420  -1.331  -1.371  -1.292  -1.138  -1.257  -1.367  -1.252  -1.265
260   L         0.946   0.953   0.977   0.784   0.792   0.844   0.986   0.994   1.022
261   L         0.946   0.953   0.977   0.784   0.792   0.844   0.986   0.994   1.022
262   E         0.946   0.953   0.977   0.895   0.906   0.947   0.986   0.994   1.022
263   Q        -0.631  -0.618  -0.524  -0.665  -0.630  -0.485  -0.896  -0.871  -0.719
264   L         0.946   0.953   0.977   0.784   0.792   0.844   0.986   0.994   1.022
265   Y        -1.420  -1.448  -1.386  -1.360  -1.393  -1.246  -1.367  -1.392  -1.282
266   E        -0.334  -0.421  -0.477  -0.128  -0.276  -0.407  -0.426  -0.556  -0.643
267   S         0.946   0.953   0.977   0.923   0.935   0.972   0.986   0.994   1.022
268   T        -0.334  -0.329  -0.468  -0.244  -0.236  -0.467  -0.426  -0.416  -0.629
269   D        -0.334  -0.329  -0.468  -0.354  -0.343  -0.629  -0.426  -0.416  -0.629
270   P        -0.334  -0.294  -0.464  -0.175  -0.105  -0.466  -0.426  -0.363  -0.622
271   I        -0.334  -0.421  -0.477  -0.258  -0.404  -0.510  -0.426  -0.556  -0.643
272   E        -0.334  -0.421  -0.477  -0.111  -0.257  -0.393  -0.426  -0.556  -0.643
273   N        -1.420  -1.448  -1.386  -1.173  -1.215  -1.165  -1.367  -1.392  -1.282
274   K         0.946   0.953   0.977   0.774   0.781   0.835   0.986   0.994   1.022
275   L         0.946   0.953   0.977   0.784   0.792   0.844   0.986   0.994   1.022
276   N        -1.420  -1.331  -1.371  -1.155  -1.018  -1.100  -1.367  -1.252  -1.265
277   S        -0.334  -0.421  -0.477  -0.566  -0.685  -0.763  -0.426  -0.556  -0.643
278   E        -2.209  -2.185  -2.029  -2.299  -2.256  -2.002  -1.837  -1.803  -1.593
279   S        -1.420  -1.468  -1.389  -1.544  -1.616  -1.461  -1.367  -1.414  -1.285
280   A         0.946   0.953   0.977   0.684   0.708   0.752   0.986   0.994   1.022
281   K        -1.420  -1.393  -1.378  -1.679  -1.629  -1.604  -1.367  -1.325  -1.273
282   E        -0.334  -0.421  -0.477  -0.341  -0.479  -0.584  -0.426  -0.556  -0.643
283   E        -0.334  -0.421  -0.477  -0.477  -0.616  -0.697  -0.426  -0.556  -0.643
284   G        -2.209  -2.185  -2.029  -1.955  -1.918  -1.685  -1.837  -1.803  -1.593
285   V        -1.420  -1.448  -1.386  -1.468  -1.510  -1.420  -1.367  -1.392  -1.282
286   E         0.946   0.953   0.977   0.895   0.906   0.947   0.986   0.994   1.022
287   K         0.946   0.953   0.977   0.774   0.781   0.835   0.986   0.994   1.022
288   V        -0.631  -0.618  -0.524  -0.894  -0.868  -0.698  -0.896  -0.871  -0.719
289   S        -1.420  -1.356  -1.376  -1.509  -1.382  -1.450  -1.367  -1.282  -1.270
290   F        -0.334  -0.421  -0.477  -0.063  -0.200  -0.306  -0.426  -0.556  -0.643
291   I        -0.631  -0.614  -0.522  -0.950  -0.909  -0.745  -0.896  -0.863  -0.716
292   N        -1.420  -1.331  -1.371  -1.194  -1.050  -1.144  -1.367  -1.252  -1.265
293   D        -1.420  -1.356  -1.376  -1.402  -1.293  -1.343  -1.367  -1.282  -1.270
294   E         0.946   0.953   0.977   0.895   0.906   0.947   0.986   0.994   1.022
295   P         0.946   0.953   0.977   1.160   1.168   1.192   0.986   0.994   1.022
296   H        -2.209  -2.185  -2.029  -2.021  -1.951  -1.746  -1.837  -1.803  -1.593
297   F         0.946   0.953   0.977   1.090   1.099   1.126   0.986   0.994   1.022
298   R         0.946   0.953   0.977   1.182   1.188   1.212   0.986   0.994   1.022
299   Y        -1.420  -1.415  -1.382  -1.091  -1.090  -1.028  -1.367  -1.355  -1.277
300   V        -0.334  -0.421  -0.477  -0.254  -0.391  -0.485  -0.426  -0.556  -0.643
301   L        -0.334  -0.421  -0.477  -0.213  -0.366  -0.506  -0.426  -0.556  -0.643
302   N         0.946   0.953   0.977   1.143   1.149   1.175   0.986   0.994   1.022
303   E        -0.334  -0.294  -0.464  -0.286  -0.230  -0.457  -0.426  -0.363  -0.622
304   D         0.946   0.953   0.977   0.977   0.987   1.023   0.986   0.994   1.022
305   Q        -0.334  -0.294  -0.464  -0.081  -0.018  -0.341  -0.426  -0.363  -0.622
306   M         0.946   0.953   0.977   1.256   1.260   1.280   0.986   0.994   1.022
307   A         0.946   0.953   0.977   0.684   0.708   0.752   0.986   0.994   1.022
308   T        -0.631  -0.622  -0.525  -0.734  -0.722  -0.557  -0.896  -0.877  -0.721
309   E        -0.334  -0.294  -0.464  -0.333  -0.275  -0.529  -0.426  -0.363  -0.622
310   K         0.946   0.953   0.977   0.774   0.781   0.835   0.986   0.994   1.022
311   L         0.946   0.953   0.977   0.784   0.792   0.844   0.986   0.994   1.022
312   S        -0.334  -0.329  -0.468  -0.247  -0.237  -0.421  -0.426  -0.416  -0.629
313   D        -1.420  -1.393  -1.378  -1.370  -1.325  -1.310  -1.367  -1.325  -1.273
314   G         0.946   0.953   0.977   1.045   1.052   1.085   0.986   0.994   1.022
315   I         0.946   0.953   0.977   0.918   0.929   0.968   0.986   0.994   1.022
316   R        -1.420  -1.393  -1.378  -1.310  -1.252  -1.305  -1.367  -1.325  -1.273
317   K        -0.334  -0.294  -0.464  -0.556  -0.489  -0.792  -0.426  -0.363  -0.622
318   F         0.946   0.953   0.977   1.090   1.099   1.126   0.986   0.994   1.022
319   S        -0.334  -0.421  -0.477  -0.566  -0.685  -0.763  -0.426  -0.556  -0.643
320   A        -0.334  -0.294  -0.464  -0.616  -0.540  -0.821  -0.426  -0.363  -0.622
321   D         0.946   0.953   0.977   0.977   0.987   1.023   0.986   0.994   1.022
322   I        -0.334  -0.421  -0.477  -0.567  -0.688  -0.765  -0.426  -0.556  -0.643
323   E        -1.420  -1.448  -1.386  -1.358  -1.417  -1.318  -1.367  -1.392  -1.282
324   A        -0.334  -0.421  -0.477  -0.336  -0.488  -0.633  -0.426  -0.556  -0.643
325   L         0.946   0.953   0.977   0.784   0.792   0.844   0.986   0.994   1.022
326   Y        -2.209  -2.185  -2.029  -1.984  -1.939  -1.712  -1.837  -1.803  -1.593
327   K        -1.420  -1.393  -1.378  -1.548  -1.508  -1.453  -1.367  -1.325  -1.273
328   L        -0.631  -0.622  -0.525  -0.950  -0.936  -0.758  -0.896  -0.877  -0.721
329   V        -1.420  -1.448  -1.386  -1.468  -1.510  -1.420  -1.367  -1.392  -1.282
330   E        -0.631  -0.622  -0.525  -0.974  -0.958  -0.778  -0.896  -0.877  -0.721
331   E        -2.209  -2.185  -2.029  -2.127  -2.082  -1.844  -1.837  -1.803  -1.593
332   K         0.946   0.953   0.977   0.774   0.781   0.835   0.986   0.994   1.022
333   M        -0.334  -0.421  -0.477  -0.354  -0.470  -0.501  -0.426  -0.556  -0.643
334   -        -1.554  -1.542  -1.405  -1.825  -1.812  -1.565  -1.524  -1.499  -1.302
335   -        -0.502  -0.518  -0.509  -0.855  -0.881  -0.828  -0.687  -0.708  -0.694
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P53228
Output conservation file - output/P53228
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
