1     M         1.890   1.929   2.011   2.121   2.181   2.311   2.089   2.154   2.293
2     S        -0.597  -0.503  -0.644  -0.593  -0.462  -0.656  -0.555  -0.434  -0.592
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     H        -0.191  -0.173  -0.162  -0.110  -0.082  -0.093  -0.389  -0.364  -0.352
6     Q        -1.332  -1.317  -1.254  -1.060  -1.045  -0.934  -1.083  -1.062  -0.975
7     M        -0.012  -0.068  -0.097   0.238   0.141   0.079  -0.131  -0.212  -0.259
8     A        -0.597  -0.660  -0.691  -0.480  -0.602  -0.659  -0.555  -0.628  -0.647
9     P         0.153   0.033  -0.053   0.269   0.081  -0.066   0.106  -0.067  -0.194
10    W         1.890   1.929   2.011   2.094   2.153   2.284   2.089   2.154   2.293
11    I        -0.135  -0.168  -0.124  -0.163  -0.208  -0.144  -0.334  -0.364  -0.308
12    P         0.153   0.112   0.003   0.300   0.229   0.078   0.106   0.043  -0.112
13    M        -0.772  -0.711  -0.742  -0.691  -0.629  -0.658  -0.775  -0.704  -0.710
14    F         0.988   0.895   0.831   1.044   0.916   0.800   0.988   0.827   0.690
15    I        -1.697  -1.678  -1.624  -1.677  -1.656  -1.564  -1.215  -1.192  -1.111
16    Q        -1.234  -1.255  -1.228  -1.157  -1.195  -1.175  -0.995  -1.009  -0.952
17    S        -0.597  -0.670  -0.701  -0.611  -0.742  -0.764  -0.555  -0.639  -0.659
18    C        -1.234  -1.255  -1.228  -0.979  -1.035  -0.999  -0.995  -1.009  -0.952
19    K         0.153   0.163  -0.001   0.191   0.212  -0.058   0.106   0.121  -0.118
20    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
21    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
22    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
23    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
24    -        -0.885  -0.867  -0.802  -0.979  -0.964  -0.851  -0.885  -0.860  -0.771
25    -        -0.885  -0.867  -0.802  -1.073  -1.055  -0.948  -0.885  -0.860  -0.771
26    N        -0.772  -0.790  -0.752  -0.823  -0.837  -0.784  -0.775  -0.786  -0.720
27    N        -0.597  -0.672  -0.700  -0.396  -0.506  -0.526  -0.555  -0.641  -0.657
28    T        -1.234  -1.245  -1.228  -1.261  -1.258  -1.245  -0.995  -1.000  -0.953
29    E        -1.234  -1.245  -1.228  -0.992  -0.987  -0.966  -0.995  -1.000  -0.953
30    P         0.988   1.049   0.869   1.098   1.179   0.938   0.988   1.085   0.759
31    F         0.153   0.033  -0.053   0.216   0.029  -0.137   0.106  -0.067  -0.194
32    V        -1.234  -1.237  -1.205  -1.023  -1.022  -0.978  -0.995  -0.993  -0.931
33    S        -0.191  -0.173  -0.162  -0.371  -0.347  -0.333  -0.389  -0.364  -0.352
34    F         1.890   1.929   2.011   1.888   1.954   2.074   2.089   2.154   2.293
35    Q         0.988   0.971   0.844   1.133   1.116   0.919   0.988   0.956   0.713
36    F         0.502   0.535   0.609   0.201   0.242   0.357   0.106   0.154   0.258
37    A         1.890   1.929   2.011   1.957   2.010   2.144   2.089   2.154   2.293
38    T         1.890   1.929   2.011   1.861   1.918   2.046   2.089   2.154   2.293
39    V         0.153   0.112   0.003   0.284   0.206   0.054   0.106   0.043  -0.112
40    D         0.153   0.097  -0.014   0.162   0.085  -0.077   0.106   0.022  -0.137
41    E        -0.772  -0.823  -0.767  -0.934  -0.998  -0.902  -0.775  -0.817  -0.736
42    L        -1.234  -1.205  -1.199  -1.151  -1.093  -1.109  -0.995  -0.962  -0.925
43    T        -0.191  -0.191  -0.162  -0.262  -0.269  -0.228  -0.389  -0.392  -0.352
44    N        -0.772  -0.793  -0.748  -0.805  -0.845  -0.784  -0.775  -0.789  -0.717
45    K        -1.697  -1.678  -1.624  -1.367  -1.328  -1.248  -1.215  -1.192  -1.111
46    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
47    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
48    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
49    P         1.890   1.929   2.011   1.912   1.966   2.099   2.089   2.154   2.293
50    R        -0.597  -0.503  -0.644  -0.376  -0.240  -0.434  -0.555  -0.434  -0.592
51    C        -0.772  -0.760  -0.740  -0.605  -0.596  -0.558  -0.775  -0.754  -0.708
52    R         1.890   1.929   2.011   1.923   1.975   2.109   2.089   2.154   2.293
53    T         1.890   1.929   2.011   1.861   1.918   2.046   2.089   2.154   2.293
54    V        -0.135  -0.126  -0.126  -0.178  -0.153  -0.134  -0.334  -0.312  -0.307
55    V         0.988   0.895   0.831   1.098   0.968   0.878   0.988   0.827   0.690
56    F        -0.772  -0.823  -0.767  -0.566  -0.613  -0.525  -0.775  -0.817  -0.736
57    R         1.890   1.929   2.011   1.923   1.975   2.109   2.089   2.154   2.293
58    D         0.616   0.691   0.690   0.500   0.633   0.596   0.327   0.457   0.420
59    F         0.616   0.641   0.654   0.573   0.616   0.629   0.327   0.362   0.349
60    L         0.988   0.895   0.831   0.983   0.845   0.757   0.988   0.827   0.690
61    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
62    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
63    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
64    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
65    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
66    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
67    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
68    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
69    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
70    F         0.988   0.895   0.831   1.036   0.910   0.785   0.988   0.827   0.690
71    H         0.153   0.200   0.009   0.192   0.260   0.001   0.106   0.173  -0.103
72    D        -1.234  -1.257  -1.208  -1.317  -1.346  -1.280  -0.995  -1.010  -0.934
73    K        -0.135  -0.163  -0.114  -0.234  -0.273  -0.207  -0.334  -0.356  -0.294
74    R        -1.234  -1.205  -1.199  -1.151  -1.097  -1.097  -0.995  -0.962  -0.925
75    T         0.616   0.680   0.688   0.388   0.495   0.481   0.327   0.435   0.417
76    N        -0.597  -0.660  -0.691  -0.545  -0.652  -0.716  -0.555  -0.628  -0.647
77    V         0.988   0.895   0.831   1.068   0.927   0.824   0.988   0.827   0.690
78    L         0.988   1.052   0.865   0.994   1.074   0.830   0.988   1.090   0.752
79    T         0.153   0.033  -0.053   0.221   0.035  -0.110   0.106  -0.067  -0.194
80    F         0.988   1.052   0.865   1.105   1.201   0.959   0.988   1.090   0.752
81    N        -1.234  -1.255  -1.228  -1.154  -1.213  -1.149  -0.995  -1.009  -0.952
82    T         1.890   1.929   2.011   1.861   1.918   2.046   2.089   2.154   2.293
83    D         1.890   1.929   2.011   1.763   1.829   1.946   2.089   2.154   2.293
84    M        -1.234  -1.245  -1.228  -1.049  -1.067  -1.015  -0.995  -1.000  -0.953
85    R         0.988   0.895   0.831   1.108   0.977   0.888   0.988   0.827   0.690
86    S        -0.135  -0.093  -0.130  -0.205  -0.151  -0.179  -0.334  -0.281  -0.318
87    S        -0.772  -0.822  -0.742  -0.850  -0.893  -0.787  -0.775  -0.816  -0.712
88    K         1.890   1.929   2.011   1.843   1.906   2.028   2.089   2.154   2.293
89    I        -1.234  -1.245  -1.228  -0.932  -0.957  -0.930  -0.995  -1.000  -0.953
90    T        -1.234  -1.245  -1.228  -1.238  -1.253  -1.239  -0.995  -1.000  -0.953
91    E         0.988   0.971   0.844   0.973   0.955   0.776   0.988   0.956   0.713
92    S        -0.135  -0.169  -0.136  -0.342  -0.380  -0.329  -0.334  -0.365  -0.321
93    F        -0.309  -0.278  -0.210  -0.492  -0.438  -0.332  -0.555  -0.512  -0.420
94    I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
95    T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
96    P        -0.772  -0.711  -0.742  -0.770  -0.702  -0.707  -0.775  -0.704  -0.710
97    N         0.988   0.895   0.831   1.070   0.947   0.852   0.988   0.827   0.690
98    S        -0.597  -0.591  -0.685  -0.592  -0.570  -0.721  -0.555  -0.548  -0.641
99    N        -0.135  -0.119  -0.122  -0.237  -0.196  -0.202  -0.334  -0.300  -0.302
100   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
101   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
102   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
103   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
104   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
105   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
106   R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
107   C        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
108   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
109   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
110   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
111   F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
112   F         0.988   1.067   0.876   1.105   1.221   0.975   0.988   1.115   0.772
113   E         1.890   1.929   2.011   1.784   1.841   1.968   2.089   2.154   2.293
114   A         0.988   0.895   0.831   1.175   1.055   0.980   0.988   0.827   0.690
115   C         0.502   0.528   0.605   0.439   0.477   0.598   0.106   0.140   0.251
116   F         0.988   0.895   0.831   1.078   0.961   0.861   0.988   0.827   0.690
117   Y         0.988   0.895   0.831   1.268   1.155   1.067   0.988   0.827   0.690
118   F         0.153   0.033  -0.053   0.208   0.018  -0.151   0.106  -0.067  -0.194
119   P        -0.597  -0.561  -0.646  -0.469  -0.420  -0.550  -0.555  -0.506  -0.595
120   E        -0.772  -0.752  -0.738  -0.848  -0.811  -0.772  -0.775  -0.746  -0.705
121   T        -0.135  -0.126  -0.126  -0.133  -0.106  -0.088  -0.334  -0.312  -0.307
122   W        -1.234  -1.255  -1.228  -0.798  -0.810  -0.780  -0.995  -1.009  -0.952
123   E        -0.772  -0.823  -0.767  -0.833  -0.884  -0.794  -0.775  -0.817  -0.736
124   Q         1.890   1.929   2.011   1.967   2.028   2.154   2.089   2.154   2.293
125   Y        -0.135  -0.169  -0.136  -0.098  -0.128  -0.081  -0.334  -0.365  -0.321
126   R         1.890   1.929   2.011   1.923   1.975   2.109   2.089   2.154   2.293
127   F        -0.135  -0.116  -0.139  -0.193  -0.169  -0.202  -0.334  -0.324  -0.332
128   S        -0.772  -0.763  -0.743  -0.835  -0.830  -0.785  -0.775  -0.758  -0.711
129   G         0.988   1.067   0.876   1.159   1.265   1.010   0.988   1.115   0.772
130   Q        -1.234  -1.196  -1.194  -0.992  -0.929  -0.926  -0.995  -0.950  -0.921
131   C        -0.135  -0.169  -0.136  -0.015  -0.058   0.001  -0.334  -0.365  -0.321
132   F        -0.772  -0.823  -0.767  -0.701  -0.750  -0.668  -0.775  -0.817  -0.736
133   T        -0.597  -0.469  -0.637  -0.537  -0.357  -0.592  -0.555  -0.393  -0.584
134   I        -0.012  -0.041  -0.107   0.087   0.038  -0.086  -0.131  -0.174  -0.272
135   S         0.543   0.571   0.636   0.118   0.154   0.248   0.186   0.226   0.314
136   K        -1.332  -1.317  -1.254  -1.419  -1.405  -1.301  -1.083  -1.062  -0.975
137   Q        -0.777  -0.781  -0.752  -0.807  -0.827  -0.795  -0.766  -0.767  -0.717
138   F        -0.777  -0.692  -0.726  -0.492  -0.347  -0.409  -0.766  -0.664  -0.688
139   K        -0.772  -0.712  -0.734  -0.806  -0.713  -0.735  -0.775  -0.705  -0.703
140   K         0.153   0.269   0.016   0.291   0.454   0.085   0.106   0.274  -0.093
141   -        -0.885  -0.870  -0.802  -0.835  -0.809  -0.705  -0.885  -0.864  -0.771
142   I        -0.777  -0.798  -0.750  -0.613  -0.634  -0.568  -0.766  -0.786  -0.714
143   P        -0.777  -0.762  -0.772  -0.914  -0.891  -0.899  -0.766  -0.746  -0.739
144   A        -0.777  -0.762  -0.772  -0.685  -0.658  -0.656  -0.766  -0.746  -0.739
145   E        -0.777  -0.797  -0.772  -0.832  -0.853  -0.820  -0.766  -0.785  -0.739
146   I        -1.332  -1.317  -1.254  -1.300  -1.274  -1.179  -1.083  -1.062  -0.975
147   V        -0.777  -0.781  -0.752  -0.685  -0.691  -0.645  -0.766  -0.767  -0.717
148   T        -0.885  -0.866  -0.802  -1.013  -0.994  -0.886  -0.885  -0.860  -0.771
149   K        -0.885  -0.866  -0.802  -0.954  -0.929  -0.826  -0.885  -0.860  -0.771
150   Y         0.764   0.760   0.731   0.875   0.861   0.791   0.602   0.584   0.500
151   D        -0.191  -0.171  -0.152  -0.417  -0.392  -0.360  -0.389  -0.362  -0.337
152   I         0.764   0.736   0.720   0.849   0.801   0.763   0.602   0.540   0.479
153   F        -0.191  -0.106  -0.148  -0.191  -0.044  -0.137  -0.389  -0.267  -0.332
154   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
155   P         0.502   0.535   0.611   0.358   0.410   0.529   0.106   0.154   0.263
156   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
157   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
158   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
159   R        -0.777  -0.674  -0.732  -0.819  -0.663  -0.745  -0.766  -0.642  -0.695
160   F        -0.777  -0.737  -0.739  -0.785  -0.743  -0.732  -0.766  -0.721  -0.702
161   S        -0.012  -0.098  -0.097  -0.114  -0.250  -0.249  -0.131  -0.256  -0.259
162   E        -0.777  -0.821  -0.772  -0.985  -1.061  -0.998  -0.766  -0.811  -0.739
163   T        -1.332  -1.308  -1.254  -1.440  -1.383  -1.322  -1.083  -1.055  -0.975
164   N        -0.012  -0.008  -0.078  -0.077  -0.072  -0.224  -0.131  -0.125  -0.231
165   D        -0.777  -0.798  -0.750  -0.943  -0.969  -0.909  -0.766  -0.787  -0.714
166   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
167   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
168   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
169   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
170   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
171   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
172   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
173   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
174   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
175   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
176   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
177   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
178   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
179   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
180   D        -0.885  -0.866  -0.802  -1.158  -1.120  -1.034  -0.885  -0.860  -0.771
181   S         0.764   0.760   0.731   0.586   0.566   0.515   0.602   0.584   0.500
182   T         0.502   0.528   0.605   0.114   0.139   0.263   0.106   0.141   0.251
183   D        -0.191  -0.225  -0.184  -0.482  -0.545  -0.487  -0.389  -0.438  -0.383
184   E        -0.191  -0.225  -0.184  -0.400  -0.457  -0.403  -0.389  -0.438  -0.383
185   E        -0.191  -0.152  -0.149  -0.323  -0.260  -0.286  -0.389  -0.335  -0.333
186   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
187   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
188   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
189   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
190   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
191   I        -0.012   0.075  -0.092   0.005   0.132  -0.117  -0.131  -0.005  -0.250
192   D        -0.222  -0.242  -0.189  -0.526  -0.559  -0.490  -0.449  -0.469  -0.394
193   T        -0.191  -0.167  -0.156  -0.417  -0.389  -0.371  -0.389  -0.358  -0.343
194   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
195   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
196   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
197   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
198   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
199   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
200   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
201   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
202   D        -0.191  -0.225  -0.184  -0.402  -0.452  -0.388  -0.389  -0.438  -0.383
203   K        -0.885  -0.866  -0.802  -1.118  -1.100  -0.993  -0.885  -0.860  -0.771
204   N        -0.885  -0.866  -0.802  -0.836  -0.810  -0.705  -0.885  -0.860  -0.771
205   N        -0.191  -0.186  -0.160  -0.167  -0.167  -0.113  -0.389  -0.384  -0.349
206   D         0.764   0.736   0.720   0.548   0.498   0.453   0.602   0.540   0.479
207   A        -0.191  -0.106  -0.148  -0.448  -0.322  -0.393  -0.389  -0.267  -0.332
208   D        -0.885  -0.866  -0.802  -1.054  -1.026  -0.928  -0.885  -0.860  -0.771
209   N        -0.885  -0.866  -0.802  -0.904  -0.864  -0.775  -0.885  -0.860  -0.771
210   N        -0.885  -0.866  -0.802  -0.907  -0.863  -0.778  -0.885  -0.860  -0.771
211   D        -0.191  -0.225  -0.184  -0.413  -0.466  -0.401  -0.389  -0.438  -0.383
212   I        -0.191  -0.225  -0.184  -0.122  -0.174  -0.119  -0.389  -0.438  -0.383
213   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
214   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
215   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
216   N        -0.191  -0.135  -0.141  -0.302  -0.213  -0.221  -0.389  -0.309  -0.322
217   K         0.502   0.528   0.605   0.131   0.169   0.282   0.106   0.141   0.250
218   L         0.764   0.800   0.760   0.672   0.718   0.659   0.602   0.658   0.556
219   I        -0.191  -0.156  -0.143  -0.268  -0.213  -0.212  -0.389  -0.339  -0.325
220   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
221   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
222   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
223   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
224   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
225   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
226   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
227   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
228   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
229   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
230   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
231   E        -0.191  -0.182  -0.162  -0.453  -0.449  -0.433  -0.389  -0.378  -0.352
232   S         0.764   0.809   0.756   0.575   0.638   0.545   0.602   0.675   0.548
233   I        -0.885  -0.871  -0.802  -1.134  -1.115  -1.010  -0.885  -0.864  -0.771
234   E         0.764   0.809   0.756   0.654   0.721   0.630   0.602   0.675   0.548
235   N        -0.191  -0.194  -0.160  -0.271  -0.280  -0.232  -0.389  -0.394  -0.349
236   D        -0.191  -0.202  -0.184  -0.226  -0.244  -0.244  -0.389  -0.406  -0.384
237   E        -0.777  -0.805  -0.772  -0.953  -1.005  -0.948  -0.766  -0.794  -0.739
238   H        -0.222  -0.175  -0.164  -0.158  -0.084  -0.052  -0.449  -0.390  -0.362
239   H        -1.234  -1.255  -1.228  -1.094  -1.157  -1.136  -0.995  -1.009  -0.952
240   E        -0.772  -0.742  -0.731  -0.743  -0.687  -0.674  -0.775  -0.738  -0.700
241   D        -1.234  -1.244  -1.208  -1.200  -1.210  -1.165  -0.995  -0.999  -0.934
242   E        -0.772  -0.700  -0.742  -0.903  -0.808  -0.878  -0.775  -0.695  -0.710
243   D        -0.012  -0.098  -0.097  -0.125  -0.252  -0.273  -0.131  -0.256  -0.259
244   D        -0.777  -0.722  -0.729  -0.793  -0.698  -0.732  -0.766  -0.700  -0.691
245   Y        -0.777  -0.737  -0.739  -0.812  -0.772  -0.742  -0.766  -0.721  -0.702
246   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
247   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
248   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
249   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
250   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
251   Y        -1.332  -1.308  -1.254  -1.232  -1.211  -1.110  -1.083  -1.055  -0.975
252   P         1.890   1.929   2.011   1.909   1.961   2.095   2.089   2.154   2.293
253   Q        -0.777  -0.779  -0.746  -0.876  -0.906  -0.840  -0.766  -0.767  -0.710
254   P        -0.777  -0.692  -0.726  -0.974  -0.837  -0.906  -0.766  -0.664  -0.688
255   Q        -0.222  -0.254  -0.167  -0.287  -0.317  -0.190  -0.449  -0.483  -0.366
256   E         0.888   0.804   0.806   0.770   0.632   0.618   0.820   0.665   0.643
257   W         1.890   1.929   2.011   2.091   2.150   2.281   2.089   2.154   2.293
258   E        -0.012   0.034  -0.051  -0.064   0.005  -0.122  -0.131  -0.065  -0.192
259   A        -1.332  -1.308  -1.254  -1.280  -1.265  -1.159  -1.083  -1.055  -0.975
260   E         1.890   1.929   2.011   1.784   1.841   1.968   2.089   2.154   2.293
261   L        -1.234  -1.263  -1.210  -0.988  -1.026  -0.920  -0.995  -1.015  -0.936
262   L        -1.697  -1.678  -1.624  -1.355  -1.315  -1.235  -1.215  -1.192  -1.111
263   R         1.890   1.929   2.011   1.923   1.975   2.109   2.089   2.154   2.293
264   Q        -0.597  -0.670  -0.701  -0.405  -0.517  -0.578  -0.555  -0.639  -0.659
265   W         1.890   1.929   2.011   2.094   2.153   2.284   2.089   2.154   2.293
266   S        -0.772  -0.789  -0.739  -1.008  -1.028  -0.953  -0.775  -0.785  -0.708
267   S        -0.772  -0.793  -0.748  -0.923  -0.967  -0.890  -0.775  -0.789  -0.717
268   L         0.988   0.895   0.831   1.022   0.897   0.827   0.988   0.827   0.690
269   S         1.890   1.929   2.011   1.748   1.801   1.931   2.089   2.154   2.293
270   R        -0.309  -0.278  -0.210  -0.475  -0.428  -0.321  -0.555  -0.512  -0.420
271   H        -1.697  -1.678  -1.624  -1.501  -1.501  -1.384  -1.215  -1.192  -1.111
272   T         0.502   0.529   0.605   0.180   0.207   0.331   0.106   0.142   0.251
273   K         0.988   0.895   0.831   1.023   0.900   0.798   0.988   0.827   0.690
274   S        -0.135  -0.176  -0.131  -0.339  -0.387  -0.317  -0.334  -0.375  -0.314
275   L         0.153   0.269   0.016   0.110   0.271  -0.101   0.106   0.274  -0.093
276   Y         0.616   0.691   0.690   0.556   0.681   0.666   0.327   0.457   0.420
277   R        -0.135  -0.176  -0.117  -0.250  -0.317  -0.233  -0.334  -0.376  -0.299
278   K         0.988   0.895   0.831   1.010   0.885   0.776   0.988   0.827   0.690
279   P         1.890   1.929   2.011   1.912   1.966   2.099   2.089   2.154   2.293
280   A        -0.772  -0.760  -0.740  -0.700  -0.684  -0.643  -0.775  -0.754  -0.708
281   P         0.988   0.895   0.831   1.057   0.914   0.804   0.988   0.827   0.690
282   G        -1.234  -1.255  -1.228  -1.000  -1.019  -0.990  -0.995  -1.009  -0.952
283   Q        -0.597  -0.483  -0.643  -0.631  -0.464  -0.702  -0.555  -0.410  -0.591
284   K        -0.772  -0.756  -0.733  -0.816  -0.802  -0.753  -0.775  -0.751  -0.703
285   L        -0.772  -0.772  -0.740  -0.542  -0.525  -0.484  -0.775  -0.770  -0.709
286   T        -0.772  -0.790  -0.752  -0.872  -0.892  -0.825  -0.775  -0.786  -0.720
287   S        -1.234  -1.212  -1.206  -1.290  -1.234  -1.246  -0.995  -0.969  -0.932
288   E         0.616   0.577   0.621   0.323   0.235   0.277   0.327   0.238   0.283
289   T        -1.234  -1.245  -1.228  -1.050  -1.070  -1.026  -0.995  -1.000  -0.953
290   S        -0.597  -0.469  -0.637  -0.522  -0.323  -0.583  -0.555  -0.393  -0.584
291   K         1.890   1.929   2.011   1.825   1.884   2.009   2.089   2.154   2.293
292   Q        -0.222  -0.193  -0.174  -0.350  -0.307  -0.272  -0.449  -0.411  -0.373
293   L        -0.135  -0.190  -0.143  -0.188  -0.271  -0.211  -0.334  -0.397  -0.335
294   D         0.616   0.608   0.639   0.296   0.272   0.289   0.327   0.298   0.320
295   K        -0.135  -0.176  -0.131  -0.325  -0.372  -0.311  -0.334  -0.375  -0.314
296   L        -0.135  -0.160  -0.141  -0.194  -0.244  -0.221  -0.334  -0.367  -0.334
297   H        -1.234  -1.263  -1.210  -0.958  -1.014  -0.935  -0.995  -1.015  -0.936
298   R         0.988   0.895   0.831   1.068   0.924   0.814   0.988   0.827   0.690
299   G         0.988   0.895   0.831   1.140   1.005   0.904   0.988   0.827   0.690
300   V         0.988   0.895   0.831   1.068   0.927   0.824   0.988   0.827   0.690
301   D         0.988   0.895   0.831   0.930   0.810   0.697   0.988   0.827   0.690
302   G         1.890   1.929   2.011   1.974   2.028   2.161   2.089   2.154   2.293
303   A        -0.777  -0.762  -0.772  -0.884  -0.873  -0.891  -0.766  -0.746  -0.739
304   K         0.153   0.176   0.006   0.269   0.314   0.072   0.106   0.140  -0.107
305   E        -0.597  -0.503  -0.644  -0.573  -0.431  -0.641  -0.555  -0.434  -0.592
306   D         0.988   1.052   0.865   0.915   1.015   0.725   0.988   1.090   0.752
307   A        -0.777  -0.779  -0.749  -0.628  -0.642  -0.599  -0.766  -0.768  -0.714
308   G         1.890   1.929   2.011   1.982   2.039   2.169   2.089   2.154   2.293
309   L         0.988   0.895   0.831   0.983   0.845   0.757   0.988   0.827   0.690
310   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
311   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
312   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
313   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
314   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
315   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
316   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
317   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
318   E        -1.234  -1.245  -1.228  -1.272  -1.276  -1.279  -0.995  -1.000  -0.953
319   N         0.988   0.895   0.831   1.061   0.934   0.836   0.988   0.827   0.690
320   F         1.890   1.929   2.011   1.888   1.954   2.074   2.089   2.154   2.293
321   G        -0.597  -0.642  -0.694  -0.429  -0.530  -0.594  -0.555  -0.608  -0.651
322   I        -0.309  -0.287  -0.211  -0.471  -0.454  -0.330  -0.555  -0.525  -0.421
323   V         1.890   1.929   2.011   1.912   1.966   2.099   2.089   2.154   2.293
324   C        -0.772  -0.823  -0.767  -0.594  -0.681  -0.592  -0.775  -0.817  -0.736
325   L         0.988   0.895   0.831   1.023   0.900   0.829   0.988   0.827   0.690
326   C        -0.135  -0.176  -0.131  -0.059  -0.112  -0.062  -0.334  -0.375  -0.314
327   V        -0.597  -0.642  -0.694  -0.376  -0.450  -0.527  -0.555  -0.608  -0.651
328   D         0.616   0.577   0.621   0.359   0.288   0.338   0.327   0.238   0.283
329   S        -1.234  -1.245  -1.228  -1.082  -1.111  -1.110  -0.995  -1.000  -0.953
330   V         1.890   1.929   2.011   1.912   1.966   2.099   2.089   2.154   2.293
331   D         0.988   0.895   0.831   0.915   0.789   0.668   0.988   0.827   0.690
332   F        -0.135  -0.070  -0.113  -0.142  -0.038  -0.105  -0.334  -0.242  -0.293
333   L        -0.135  -0.126  -0.126  -0.126  -0.110  -0.079  -0.334  -0.312  -0.307
334   N        -0.597  -0.559  -0.672  -0.570  -0.502  -0.716  -0.555  -0.503  -0.625
335   L         0.988   0.971   0.844   0.983   0.952   0.778   0.988   0.956   0.713
336   K        -0.772  -0.783  -0.746  -0.948  -0.954  -0.911  -0.775  -0.779  -0.715
337   E        -0.772  -0.771  -0.747  -0.780  -0.772  -0.732  -0.775  -0.769  -0.715
338   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
339   R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
340   G        -0.191  -0.236  -0.184  -0.214  -0.306  -0.219  -0.389  -0.454  -0.383
341   G         0.616   0.680   0.688   0.500   0.611   0.593   0.327   0.435   0.417
342   E        -1.234  -1.182  -1.191  -1.086  -0.996  -1.010  -0.995  -0.937  -0.918
343   R         1.890   1.929   2.011   1.923   1.975   2.109   2.089   2.154   2.293
344   W        -1.234  -1.255  -1.228  -0.888  -0.932  -0.887  -0.995  -1.009  -0.952
345   I         0.988   0.895   0.831   1.123   0.989   0.878   0.988   0.827   0.690
346   F        -0.135  -0.176  -0.131  -0.061  -0.091  -0.022  -0.334  -0.375  -0.314
347   Q        -1.234  -1.263  -1.210  -1.084  -1.136  -1.055  -0.995  -1.015  -0.936
348   K        -0.135  -0.048  -0.108  -0.234  -0.093  -0.196  -0.334  -0.211  -0.286
349   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
350   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
351   D         1.890   1.929   2.011   1.791   1.858   1.975   2.089   2.154   2.293
352   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
353   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
354   D        -1.234  -1.204  -1.199  -1.200  -1.143  -1.166  -0.995  -0.961  -0.926
355   E        -0.772  -0.721  -0.727  -0.875  -0.800  -0.798  -0.775  -0.718  -0.697
356   D        -1.234  -1.225  -1.202  -1.159  -1.146  -1.095  -0.995  -0.981  -0.928
357   L        -0.772  -0.761  -0.732  -0.829  -0.806  -0.764  -0.775  -0.755  -0.702
358   W         1.890   1.929   2.011   2.094   2.153   2.284   2.089   2.154   2.293
359   E        -0.772  -0.752  -0.738  -0.941  -0.913  -0.873  -0.775  -0.746  -0.705
360   E         0.988   0.895   0.831   0.929   0.790   0.677   0.988   0.827   0.690
361   Q         0.153   0.099  -0.018   0.348   0.263   0.085   0.106   0.025  -0.143
362   E         0.988   0.895   0.831   0.964   0.836   0.740   0.988   0.827   0.690
363   V         1.890   1.929   2.011   1.912   1.966   2.099   2.089   2.154   2.293
364   C         0.988   0.895   0.831   1.276   1.150   1.041   0.988   0.827   0.690
365   P         0.988   0.895   0.831   1.089   0.956   0.862   0.988   0.827   0.690
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P53210
Output conservation file - output/P53210
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
