1     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
2     M         1.329   1.330   1.349   1.554   1.556   1.583   1.392   1.392   1.415
3     S        -0.159  -0.158  -0.205  -0.183  -0.181  -0.245  -0.282  -0.280  -0.352
4     R        -0.159  -0.158  -0.205  -0.143  -0.140  -0.239  -0.282  -0.280  -0.352
5     L        -1.240  -1.239  -1.207  -1.401  -1.391  -1.343  -1.119  -1.118  -1.063
6     A        -0.159  -0.145  -0.201  -0.426  -0.405  -0.475  -0.282  -0.260  -0.345
7     H         1.329   1.330   1.349   1.500   1.500   1.529   1.392   1.392   1.415
8     N        -0.292  -0.291  -0.264  -0.496  -0.496  -0.447  -0.491  -0.491  -0.444
9     K         1.329   1.330   1.349   1.266   1.267   1.298   1.392   1.392   1.415
10    A        -1.240  -1.239  -1.207  -1.164  -1.167  -1.108  -1.119  -1.118  -1.063
11    L         1.329   1.330   1.349   1.037   1.039   1.070   1.392   1.392   1.415
12    P        -1.240  -1.239  -1.207  -1.115  -1.114  -1.060  -1.119  -1.118  -1.063
13    Y        -1.240  -1.239  -1.207  -1.418  -1.420  -1.359  -1.119  -1.118  -1.063
14    K        -0.159  -0.158  -0.205  -0.244  -0.242  -0.308  -0.282  -0.280  -0.352
15    I        -0.159  -0.145  -0.201  -0.194  -0.169  -0.277  -0.282  -0.260  -0.345
16    I        -0.159  -0.158  -0.205  -0.220  -0.218  -0.286  -0.282  -0.280  -0.352
17    V         1.329   1.330   1.349   1.445   1.445   1.474   1.392   1.392   1.415
18    D        -0.159  -0.158  -0.205  -0.143  -0.141  -0.223  -0.282  -0.280  -0.352
19    L         1.329   1.330   1.349   1.037   1.039   1.070   1.392   1.392   1.415
20    S        -0.159  -0.145  -0.201  -0.143  -0.119  -0.227  -0.282  -0.260  -0.345
21    F        -0.159  -0.173  -0.206  -0.089  -0.112  -0.163  -0.282  -0.304  -0.352
22    H        -0.159  -0.173  -0.206  -0.075  -0.102  -0.172  -0.282  -0.304  -0.352
23    R        -0.159  -0.145  -0.201   0.005   0.029  -0.068  -0.282  -0.260  -0.345
24    T        -0.159  -0.173  -0.206  -0.103  -0.130  -0.200  -0.282  -0.304  -0.352
25    R        -1.240  -1.239  -1.207  -1.175  -1.175  -1.120  -1.119  -1.118  -1.063
26    L        -0.292  -0.291  -0.264  -0.677  -0.677  -0.626  -0.491  -0.491  -0.444
27    P        -0.292  -0.291  -0.264  -0.363  -0.363  -0.315  -0.491  -0.491  -0.444
28    S        -0.292  -0.291  -0.264  -0.544  -0.544  -0.495  -0.491  -0.491  -0.444
29    D        -0.292  -0.291  -0.264  -0.331  -0.330  -0.283  -0.491  -0.491  -0.444
30    V        -0.292  -0.291  -0.264  -0.273  -0.272  -0.226  -0.491  -0.491  -0.444
31    S        -1.240  -1.239  -1.207  -1.164  -1.162  -1.108  -1.119  -1.118  -1.063
32    S        -1.240  -1.239  -1.207  -1.265  -1.265  -1.208  -1.119  -1.118  -1.063
33    L        -1.240  -1.239  -1.207  -1.373  -1.365  -1.315  -1.119  -1.118  -1.063
34    I        -0.159  -0.145  -0.201  -0.149  -0.124  -0.233  -0.282  -0.260  -0.345
35    K        -1.240  -1.239  -1.207  -1.225  -1.222  -1.169  -1.119  -1.118  -1.063
36    F        -1.240  -1.239  -1.207  -1.019  -1.019  -0.965  -1.119  -1.118  -1.063
37    E        -1.240  -1.239  -1.207  -1.153  -1.151  -1.097  -1.119  -1.118  -1.063
38    Q        -1.240  -1.239  -1.207  -1.233  -1.240  -1.177  -1.119  -1.118  -1.063
39    R        -1.240  -1.239  -1.207  -1.138  -1.136  -1.082  -1.119  -1.118  -1.063
40    P         1.329   1.330   1.349   1.364   1.365   1.394   1.392   1.392   1.415
41    A         1.329   1.330   1.349   1.426   1.425   1.456   1.392   1.392   1.415
42    I         1.329   1.330   1.349   1.251   1.252   1.282   1.392   1.392   1.415
43    I         1.329   1.330   1.349   1.251   1.252   1.282   1.392   1.392   1.415
44    N        -0.159  -0.173  -0.206  -0.137  -0.159  -0.206  -0.282  -0.304  -0.352
45    I        -0.159  -0.145  -0.201  -0.513  -0.488  -0.577  -0.282  -0.260  -0.345
46    H         1.329   1.330   1.349   1.500   1.500   1.529   1.392   1.392   1.415
47    G         1.329   1.330   1.349   1.439   1.439   1.468   1.392   1.392   1.415
48    L        -0.159  -0.173  -0.206  -0.417  -0.436  -0.470  -0.282  -0.304  -0.352
49    L        -0.159  -0.145  -0.201  -0.279  -0.250  -0.380  -0.282  -0.260  -0.345
50    G         1.329   1.330   1.349   1.439   1.439   1.468   1.392   1.392   1.415
51    S        -0.159  -0.173  -0.206  -0.218  -0.240  -0.287  -0.282  -0.304  -0.352
52    H        -0.159  -0.173  -0.206  -0.092  -0.120  -0.192  -0.282  -0.304  -0.352
53    V        -1.240  -1.239  -1.207  -1.168  -1.168  -1.112  -1.119  -1.118  -1.063
54    M        -0.159  -0.173  -0.206   0.079   0.056  -0.001  -0.282  -0.304  -0.352
55    F         1.329   1.330   1.349   1.389   1.390   1.419   1.392   1.392   1.415
56    H        -0.159  -0.173  -0.206  -0.092  -0.120  -0.192  -0.282  -0.304  -0.352
57    S        -0.159  -0.173  -0.206  -0.247  -0.270  -0.321  -0.282  -0.304  -0.352
58    L         1.329   1.330   1.349   1.037   1.039   1.070   1.392   1.392   1.415
59    N        -0.159  -0.173  -0.206  -0.160  -0.183  -0.233  -0.282  -0.304  -0.352
60    K        -0.159  -0.158  -0.205  -0.244  -0.242  -0.308  -0.282  -0.280  -0.352
61    L        -1.240  -1.239  -1.207  -1.336  -1.327  -1.279  -1.119  -1.118  -1.063
62    L         1.329   1.330   1.349   1.037   1.039   1.070   1.392   1.392   1.415
63    S        -1.240  -1.239  -1.207  -1.093  -1.090  -1.038  -1.119  -1.118  -1.063
64    R        -1.240  -1.239  -1.207  -1.284  -1.286  -1.227  -1.119  -1.118  -1.063
65    K        -1.240  -1.239  -1.207  -1.195  -1.192  -1.139  -1.119  -1.118  -1.063
66    L        -0.159  -0.158  -0.205  -0.444  -0.441  -0.503  -0.282  -0.280  -0.352
67    D        -1.240  -1.239  -1.207  -1.229  -1.232  -1.173  -1.119  -1.118  -1.063
68    A        -0.159  -0.145  -0.201  -0.025  -0.002  -0.098  -0.282  -0.260  -0.345
69    D         1.329   1.330   1.349   1.377   1.377   1.407   1.392   1.392   1.415
70    I         1.329   1.330   1.349   1.251   1.252   1.282   1.392   1.392   1.415
71    F        -0.159  -0.145  -0.201  -0.058  -0.034  -0.134  -0.282  -0.260  -0.345
72    S        -0.159  -0.158  -0.205  -0.264  -0.261  -0.341  -0.282  -0.280  -0.352
73    V         1.329   1.330   1.349   1.445   1.445   1.474   1.392   1.392   1.415
74    D         1.329   1.330   1.349   1.377   1.377   1.407   1.392   1.392   1.415
75    V        -0.159  -0.145  -0.201  -0.417  -0.395  -0.464  -0.282  -0.260  -0.345
76    R         1.329   1.330   1.349   1.445   1.447   1.474   1.392   1.392   1.415
77    N         1.329   1.330   1.349   1.327   1.328   1.357   1.392   1.392   1.415
78    H         1.329   1.330   1.349   1.500   1.500   1.529   1.392   1.392   1.415
79    G         1.329   1.330   1.349   1.439   1.439   1.468   1.392   1.392   1.415
80    I        -1.240  -1.239  -1.207  -1.272  -1.269  -1.216  -1.119  -1.118  -1.063
81    S         1.329   1.330   1.349   1.264   1.265   1.295   1.392   1.392   1.415
82    P         1.329   1.330   1.349   1.364   1.365   1.394   1.392   1.392   1.415
83    K        -1.240  -1.239  -1.207  -1.292  -1.291  -1.235  -1.119  -1.118  -1.063
84    A         1.329   1.330   1.349   1.426   1.425   1.456   1.392   1.392   1.415
85    I        -1.240  -1.239  -1.207  -1.225  -1.226  -1.169  -1.119  -1.118  -1.063
86    P         1.329   1.330   1.349   1.364   1.365   1.394   1.392   1.392   1.415
87    Y         1.329   1.330   1.349   1.457   1.458   1.486   1.392   1.392   1.415
88    D         1.329   1.330   1.349   1.377   1.377   1.407   1.392   1.392   1.415
89    Y         1.329   1.330   1.349   1.457   1.458   1.486   1.392   1.392   1.415
90    T        -1.240  -1.239  -1.207  -1.389  -1.390  -1.331  -1.119  -1.118  -1.063
91    T         1.329   1.330   1.349   1.476   1.476   1.504   1.392   1.392   1.415
92    L         1.329   1.330   1.349   1.037   1.039   1.070   1.392   1.392   1.415
93    T        -0.159  -0.145  -0.201  -0.194  -0.173  -0.252  -0.282  -0.260  -0.345
94    N        -0.159  -0.145  -0.201  -0.300  -0.277  -0.368  -0.282  -0.260  -0.345
95    D         1.329   1.330   1.349   1.377   1.377   1.407   1.392   1.392   1.415
96    L        -0.159  -0.145  -0.201  -0.411  -0.382  -0.505  -0.282  -0.260  -0.345
97    I        -0.159  -0.173  -0.206  -0.220  -0.242  -0.287  -0.282  -0.304  -0.352
98    Y        -1.240  -1.239  -1.207  -0.940  -0.939  -0.887  -1.119  -1.118  -1.063
99    F        -0.159  -0.158  -0.205  -0.044  -0.042  -0.109  -0.282  -0.280  -0.352
100   I         1.329   1.330   1.349   1.251   1.252   1.282   1.392   1.392   1.415
101   E        -1.240  -1.239  -1.207  -1.187  -1.190  -1.131  -1.119  -1.118  -1.063
102   T        -0.159  -0.158  -0.205  -0.047  -0.045  -0.132  -0.282  -0.280  -0.352
103   H        -1.240  -1.239  -1.207  -1.016  -1.013  -0.961  -1.119  -1.118  -1.063
104   I        -0.159  -0.173  -0.206  -0.220  -0.242  -0.287  -0.282  -0.304  -0.352
105   G        -0.159  -0.158  -0.205  -0.044  -0.043  -0.120  -0.282  -0.280  -0.352
106   L        -1.240  -1.239  -1.207  -1.296  -1.288  -1.239  -1.119  -1.118  -1.063
107   E         1.329   1.330   1.349   1.420   1.420   1.450   1.392   1.392   1.415
108   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
109   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
110   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
111   R         1.329   1.330   1.349   1.445   1.447   1.474   1.392   1.392   1.415
112   P         1.329   1.330   1.349   1.364   1.365   1.394   1.392   1.392   1.415
113   I        -0.159  -0.173  -0.206  -0.220  -0.242  -0.287  -0.282  -0.304  -0.352
114   Y        -0.159  -0.173  -0.206   0.014  -0.008  -0.056  -0.282  -0.304  -0.352
115   L        -0.159  -0.173  -0.206  -0.362  -0.379  -0.406  -0.282  -0.304  -0.352
116   L        -0.159  -0.145  -0.201  -0.411  -0.382  -0.505  -0.282  -0.260  -0.345
117   G         1.329   1.330   1.349   1.439   1.439   1.468   1.392   1.392   1.415
118   F         1.329   1.330   1.349   1.389   1.390   1.419   1.392   1.392   1.415
119   S         1.329   1.330   1.349   1.264   1.265   1.295   1.392   1.392   1.415
120   M        -0.159  -0.145  -0.201  -0.362  -0.342  -0.401  -0.282  -0.260  -0.345
121   G         1.329   1.330   1.349   1.439   1.439   1.468   1.392   1.392   1.415
122   G         1.329   1.330   1.349   1.439   1.439   1.468   1.392   1.392   1.415
123   K         1.329   1.330   1.349   1.226   1.225   1.257   1.392   1.392   1.415
124   I        -0.159  -0.145  -0.201  -0.131  -0.106  -0.217  -0.282  -0.260  -0.345
125   A        -0.159  -0.173  -0.206  -0.143  -0.170  -0.236  -0.282  -0.304  -0.352
126   L         1.329   1.330   1.349   1.037   1.039   1.070   1.392   1.392   1.415
127   L        -0.159  -0.173  -0.206  -0.513  -0.535  -0.585  -0.282  -0.304  -0.352
128   T        -0.159  -0.145  -0.201  -0.194  -0.173  -0.252  -0.282  -0.260  -0.345
129   T        -0.159  -0.158  -0.205  -0.098  -0.095  -0.192  -0.282  -0.280  -0.352
130   L         1.329   1.330   1.349   1.037   1.039   1.070   1.392   1.392   1.415
131   Y        -0.159  -0.145  -0.201  -0.203  -0.181  -0.262  -0.282  -0.260  -0.345
132   K        -1.240  -1.239  -1.207  -1.214  -1.211  -1.158  -1.119  -1.118  -1.063
133   N        -1.240  -1.239  -1.207  -1.063  -1.060  -1.008  -1.119  -1.118  -1.063
134   I        -0.159  -0.173  -0.206  -0.143  -0.162  -0.195  -0.282  -0.304  -0.352
135   N         1.329   1.330   1.349   1.327   1.328   1.357   1.392   1.392   1.415
136   I        -0.159  -0.158  -0.205  -0.220  -0.218  -0.286  -0.282  -0.280  -0.352
137   R        -0.159  -0.158  -0.205  -0.143  -0.140  -0.239  -0.282  -0.280  -0.352
138   K        -0.159  -0.173  -0.206  -0.247  -0.270  -0.312  -0.282  -0.304  -0.352
139   C         1.329   1.330   1.349   1.609   1.609   1.636   1.392   1.392   1.415
140   I        -0.159  -0.173  -0.206  -0.220  -0.242  -0.287  -0.282  -0.304  -0.352
141   S         1.329   1.330   1.349   1.264   1.265   1.295   1.392   1.392   1.415
142   I         1.329   1.330   1.349   1.251   1.252   1.282   1.392   1.392   1.415
143   D         1.329   1.330   1.349   1.377   1.377   1.407   1.392   1.392   1.415
144   L        -0.159  -0.173  -0.206  -0.513  -0.535  -0.585  -0.282  -0.304  -0.352
145   P         1.329   1.330   1.349   1.364   1.365   1.394   1.392   1.392   1.415
146   P         1.329   1.330   1.349   1.364   1.365   1.394   1.392   1.392   1.415
147   Y         1.329   1.330   1.349   1.457   1.458   1.486   1.392   1.392   1.415
148   E         1.329   1.330   1.349   1.420   1.420   1.450   1.392   1.392   1.415
149   T        -0.159  -0.158  -0.205  -0.197  -0.194  -0.312  -0.282  -0.280  -0.352
150   P        -0.159  -0.158  -0.205  -0.149  -0.146  -0.227  -0.282  -0.280  -0.352
151   E        -1.240  -1.239  -1.207  -1.187  -1.187  -1.131  -1.119  -1.118  -1.063
152   L        -0.159  -0.158  -0.205  -0.417  -0.414  -0.470  -0.282  -0.280  -0.352
153   D         1.329   1.330   1.349   1.377   1.377   1.407   1.392   1.392   1.415
154   P        -0.159  -0.158  -0.205  -0.149  -0.146  -0.227  -0.282  -0.280  -0.352
155   M        -0.159  -0.173  -0.206  -0.030  -0.057  -0.132  -0.282  -0.304  -0.352
156   I        -1.240  -1.239  -1.207  -1.447  -1.449  -1.388  -1.119  -1.118  -1.063
157   L        -0.159  -0.158  -0.205  -0.362  -0.359  -0.405  -0.282  -0.280  -0.352
158   Q        -0.159  -0.173  -0.206   0.038   0.014  -0.048  -0.282  -0.304  -0.352
159   N         1.329   1.330   1.349   1.327   1.328   1.357   1.392   1.392   1.415
160   Y        -0.159  -0.158  -0.205  -0.058  -0.056  -0.141  -0.282  -0.280  -0.352
161   D        -0.159  -0.158  -0.205  -0.117  -0.115  -0.193  -0.282  -0.280  -0.352
162   L        -0.159  -0.173  -0.206  -0.402  -0.420  -0.452  -0.282  -0.304  -0.352
163   I        -0.159  -0.158  -0.205  -0.411  -0.407  -0.514  -0.282  -0.280  -0.352
164   M        -1.240  -1.239  -1.207  -1.229  -1.236  -1.173  -1.119  -1.118  -1.063
165   R        -0.159  -0.145  -0.201  -0.244  -0.223  -0.302  -0.282  -0.260  -0.345
166   I         1.329   1.330   1.349   1.251   1.252   1.282   1.392   1.392   1.415
167   I        -0.159  -0.158  -0.205  -0.220  -0.218  -0.286  -0.282  -0.280  -0.352
168   R        -1.240  -1.239  -1.207  -1.245  -1.245  -1.188  -1.119  -1.118  -1.063
169   R        -0.159  -0.173  -0.206  -0.047  -0.070  -0.126  -0.282  -0.304  -0.352
170   D        -0.159  -0.145  -0.201  -0.098  -0.074  -0.172  -0.282  -0.260  -0.345
171   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
172   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
173   V        -1.240  -1.239  -1.207  -1.149  -1.148  -1.093  -1.119  -1.118  -1.063
174   K        -0.159  -0.173  -0.206  -0.244  -0.267  -0.309  -0.282  -0.304  -0.352
175   I        -0.159  -0.158  -0.205  -0.220  -0.218  -0.286  -0.282  -0.280  -0.352
176   L        -1.240  -1.239  -1.207  -1.426  -1.421  -1.368  -1.119  -1.118  -1.063
177   R        -0.159  -0.173  -0.206  -0.143  -0.169  -0.240  -0.282  -0.304  -0.352
178   G        -0.159  -0.158  -0.205  -0.131  -0.129  -0.224  -0.282  -0.280  -0.352
179   S        -1.240  -1.239  -1.207  -1.063  -1.060  -1.008  -1.119  -1.118  -1.063
180   P        -0.159  -0.173  -0.206  -0.103  -0.126  -0.174  -0.282  -0.304  -0.352
181   S        -0.159  -0.173  -0.206  -0.264  -0.287  -0.342  -0.282  -0.304  -0.352
182   W         1.329   1.330   1.349   1.650   1.651   1.677   1.392   1.392   1.415
183   Q        -0.159  -0.145  -0.201  -0.194  -0.175  -0.244  -0.282  -0.260  -0.345
184   K        -1.240  -1.239  -1.207  -1.119  -1.115  -1.063  -1.119  -1.118  -1.063
185   K        -0.159  -0.158  -0.205  -0.276  -0.275  -0.346  -0.282  -0.280  -0.352
186   V        -0.159  -0.158  -0.205  -0.131  -0.129  -0.226  -0.282  -0.280  -0.352
187   L         1.329   1.330   1.349   1.037   1.039   1.070   1.392   1.392   1.415
188   E        -1.240  -1.239  -1.207  -1.108  -1.108  -1.052  -1.119  -1.118  -1.063
189   L        -1.240  -1.239  -1.207  -1.336  -1.331  -1.279  -1.119  -1.118  -1.063
190   F         1.329   1.330   1.349   1.389   1.390   1.419   1.392   1.392   1.415
191   K        -0.159  -0.158  -0.205  -0.244  -0.242  -0.308  -0.282  -0.280  -0.352
192   S        -1.240  -1.239  -1.207  -1.175  -1.173  -1.120  -1.119  -1.118  -1.063
193   L         1.329   1.330   1.349   0.983   0.984   1.017   1.392   1.392   1.415
194   E        -0.292  -0.291  -0.264  -0.350  -0.350  -0.303  -0.491  -0.491  -0.444
195   C        -0.292  -0.291  -0.264  -0.122  -0.121  -0.077  -0.491  -0.491  -0.444
196   N         1.329   1.330   1.349   1.327   1.328   1.357   1.392   1.392   1.415
197   K         1.329   1.330   1.349   1.226   1.225   1.257   1.392   1.392   1.415
198   -         1.329   1.330   1.349   1.605   1.606   1.633   1.392   1.392   1.415
199   R        -0.159  -0.145  -0.201  -0.151  -0.128  -0.215  -0.282  -0.260  -0.345
200   K        -1.240  -1.239  -1.207  -1.093  -1.086  -1.038  -1.119  -1.118  -1.063
201   C        -0.159  -0.145  -0.201  -0.075  -0.054  -0.126  -0.282  -0.260  -0.345
202   G         1.329   1.330   1.349   1.465   1.466   1.494   1.392   1.392   1.415
203   G        -1.240  -1.239  -1.207  -1.130  -1.130  -1.075  -1.119  -1.118  -1.063
204   A        -1.240  -1.239  -1.207  -1.126  -1.126  -1.071  -1.119  -1.118  -1.063
205   V        -0.159  -0.173  -0.206  -0.226  -0.256  -0.340  -0.282  -0.304  -0.352
206   A         1.329   1.330   1.349   1.426   1.425   1.456   1.392   1.392   1.415
207   L        -0.159  -0.173  -0.206  -0.417  -0.435  -0.470  -0.282  -0.304  -0.352
208   Y         1.329   1.330   1.349   1.457   1.458   1.486   1.392   1.392   1.415
209   F         1.329   1.330   1.349   1.389   1.390   1.419   1.392   1.392   1.415
210   A         1.329   1.330   1.349   1.426   1.425   1.456   1.392   1.392   1.415
211   N        -0.159  -0.173  -0.206  -0.160  -0.183  -0.233  -0.282  -0.304  -0.352
212   G         1.329   1.330   1.349   1.439   1.439   1.468   1.392   1.392   1.415
213   F         1.329   1.330   1.349   1.389   1.390   1.419   1.392   1.392   1.415
214   L        -0.159  -0.173  -0.206  -0.417  -0.436  -0.470  -0.282  -0.304  -0.352
215   S        -1.240  -1.239  -1.207  -1.063  -1.057  -1.008  -1.119  -1.118  -1.063
216   V        -1.240  -1.239  -1.207  -1.104  -1.105  -1.049  -1.119  -1.118  -1.063
217   K        -0.159  -0.173  -0.206  -0.282  -0.306  -0.354  -0.282  -0.304  -0.352
218   S        -1.240  -1.239  -1.207  -1.198  -1.195  -1.142  -1.119  -1.118  -1.063
219   N         1.329   1.330   1.349   1.327   1.328   1.357   1.392   1.392   1.415
220   N         1.329   1.330   1.349   1.312   1.313   1.343   1.392   1.392   1.415
221   V        -0.292  -0.291  -0.264  -0.260  -0.259  -0.213  -0.491  -0.491  -0.444
222   H        -0.292  -0.291  -0.264  -0.357  -0.356  -0.309  -0.491  -0.491  -0.444
223   Q        -0.292  -0.291  -0.264  -0.350  -0.350  -0.303  -0.491  -0.491  -0.444
224   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
225   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
226   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
227   H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
228   Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
229   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
230   Q        -1.240  -1.239  -1.207  -1.052  -1.051  -0.997  -1.119  -1.118  -1.063
231   Q        -1.240  -1.239  -1.207  -1.089  -1.092  -1.034  -1.119  -1.118  -1.063
232   Q        -1.240  -1.239  -1.207  -1.218  -1.217  -1.161  -1.119  -1.118  -1.063
233   H        -1.240  -1.239  -1.207  -1.153  -1.158  -1.097  -1.119  -1.118  -1.063
234   D        -0.159  -0.158  -0.205  -0.160  -0.157  -0.244  -0.282  -0.280  -0.352
235   P        -1.240  -1.239  -1.207  -1.145  -1.144  -1.090  -1.119  -1.118  -1.063
236   Y        -0.159  -0.173  -0.206  -0.058  -0.083  -0.142  -0.282  -0.304  -0.352
237   I        -0.159  -0.145  -0.201  -0.513  -0.488  -0.577  -0.282  -0.260  -0.345
238   N        -1.240  -1.239  -1.207  -1.063  -1.060  -1.008  -1.119  -1.118  -1.063
239   Y        -0.159  -0.173  -0.206  -0.058  -0.083  -0.142  -0.282  -0.304  -0.352
240   S        -1.240  -1.239  -1.207  -1.296  -1.298  -1.239  -1.119  -1.118  -1.063
241   M        -1.240  -1.239  -1.207  -0.916  -0.914  -0.862  -1.119  -1.118  -1.063
242   P         1.329   1.330   1.349   1.364   1.365   1.394   1.392   1.392   1.415
243   L         1.329   1.330   1.349   1.037   1.039   1.070   1.392   1.392   1.415
244   S        -1.240  -1.239  -1.207  -1.300  -1.301  -1.243  -1.119  -1.118  -1.063
245   S        -1.240  -1.239  -1.207  -1.393  -1.395  -1.335  -1.119  -1.118  -1.063
246   M         1.329   1.330   1.349   1.554   1.556   1.583   1.392   1.392   1.415
247   P         1.329   1.330   1.349   1.364   1.365   1.394   1.392   1.392   1.415
248   N        -0.159  -0.145  -0.201  -0.160  -0.135  -0.236  -0.282  -0.260  -0.345
249   L        -0.159  -0.158  -0.205  -0.513  -0.509  -0.584  -0.282  -0.280  -0.352
250   L        -0.159  -0.158  -0.205  -0.513  -0.509  -0.584  -0.282  -0.280  -0.352
251   D        -0.159  -0.158  -0.205  -0.114  -0.113  -0.189  -0.282  -0.280  -0.352
252   E         1.329   1.330   1.349   1.420   1.420   1.450   1.392   1.392   1.415
253   V        -1.240  -1.239  -1.207  -1.410  -1.415  -1.351  -1.119  -1.118  -1.063
254   K         1.329   1.330   1.349   1.226   1.225   1.257   1.392   1.392   1.415
255   K        -0.159  -0.173  -0.206  -0.253  -0.277  -0.319  -0.282  -0.304  -0.352
256   W         1.329   1.330   1.349   1.650   1.651   1.677   1.392   1.392   1.415
257   P         1.329   1.330   1.349   1.364   1.365   1.394   1.392   1.392   1.415
258   D        -0.159  -0.158  -0.205  -0.189  -0.186  -0.278  -0.282  -0.280  -0.352
259   L        -1.240  -1.239  -1.207  -1.439  -1.436  -1.380  -1.119  -1.118  -1.063
260   S        -1.240  -1.239  -1.207  -1.145  -1.142  -1.090  -1.119  -1.118  -1.063
261   N        -1.240  -1.239  -1.207  -1.233  -1.231  -1.177  -1.119  -1.118  -1.063
262   Q        -1.240  -1.239  -1.207  -1.253  -1.253  -1.196  -1.119  -1.118  -1.063
263   R        -1.240  -1.239  -1.207  -1.115  -1.113  -1.060  -1.119  -1.118  -1.063
264   D        -1.240  -1.239  -1.207  -1.141  -1.141  -1.086  -1.119  -1.118  -1.063
265   F        -1.240  -1.239  -1.207  -1.078  -1.077  -1.023  -1.119  -1.118  -1.063
266   F        -1.240  -1.239  -1.207  -1.012  -1.011  -0.958  -1.119  -1.118  -1.063
267   Q        -1.240  -1.239  -1.207  -1.005  -1.006  -0.951  -1.119  -1.118  -1.063
268   K        -1.240  -1.239  -1.207  -1.210  -1.208  -1.154  -1.119  -1.118  -1.063
269   G        -1.240  -1.239  -1.207  -1.019  -1.019  -0.965  -1.119  -1.118  -1.063
270   T        -1.240  -1.239  -1.207  -1.089  -1.087  -1.034  -1.119  -1.118  -1.063
271   A        -1.240  -1.239  -1.207  -1.141  -1.140  -1.086  -1.119  -1.118  -1.063
272   S        -0.159  -0.145  -0.201  -0.030  -0.003  -0.121  -0.282  -0.260  -0.345
273   R        -1.240  -1.239  -1.207  -1.426  -1.428  -1.368  -1.119  -1.118  -1.063
274   K        -0.159  -0.145  -0.201  -0.218  -0.192  -0.301  -0.282  -0.260  -0.345
275   V        -0.159  -0.158  -0.205  -0.030  -0.029  -0.105  -0.282  -0.280  -0.352
276   L         1.329   1.330   1.349   1.037   1.039   1.070   1.392   1.392   1.415
277   F         1.329   1.330   1.349   1.389   1.390   1.419   1.392   1.392   1.415
278   M        -0.159  -0.173  -0.206   0.127   0.106   0.056  -0.282  -0.304  -0.352
279   K         1.329   1.330   1.349   1.226   1.225   1.257   1.392   1.392   1.415
280   G        -0.159  -0.173  -0.206  -0.058  -0.083  -0.138  -0.282  -0.304  -0.352
281   L         1.329   1.330   1.349   1.037   1.039   1.070   1.392   1.392   1.415
282   Q        -1.240  -1.239  -1.207  -1.074  -1.079  -1.019  -1.119  -1.118  -1.063
283   S         1.329   1.330   1.349   1.264   1.265   1.295   1.392   1.392   1.415
284   N        -1.240  -1.239  -1.207  -1.272  -1.270  -1.216  -1.119  -1.118  -1.063
285   F         1.329   1.330   1.349   1.389   1.390   1.419   1.392   1.392   1.415
286   I         1.329   1.330   1.349   1.251   1.252   1.282   1.392   1.392   1.415
287   N        -1.240  -1.239  -1.207  -1.360  -1.360  -1.303  -1.119  -1.118  -1.063
288   N        -0.159  -0.173  -0.206  -0.235  -0.259  -0.322  -0.282  -0.304  -0.352
289   D         1.329   1.330   1.349   1.377   1.377   1.407   1.392   1.392   1.415
290   Y         1.329   1.330   1.349   1.457   1.458   1.486   1.392   1.392   1.415
291   S         1.329   1.330   1.349   1.264   1.265   1.295   1.392   1.392   1.415
292   L         1.329   1.330   1.349   1.037   1.039   1.070   1.392   1.392   1.415
293   L         1.329   1.330   1.349   1.037   1.039   1.070   1.392   1.392   1.415
294   R        -1.240  -1.239  -1.207  -1.284  -1.286  -1.227  -1.119  -1.118  -1.063
295   Y        -1.240  -1.239  -1.207  -1.145  -1.149  -1.090  -1.119  -1.118  -1.063
296   N        -0.159  -0.145  -0.201  -0.003   0.023  -0.088  -0.282  -0.260  -0.345
297   F        -0.159  -0.145  -0.201  -0.058  -0.034  -0.134  -0.282  -0.260  -0.345
298   P         1.329   1.330   1.349   1.364   1.365   1.394   1.392   1.392   1.415
299   C        -1.240  -1.239  -1.207  -0.951  -0.954  -0.897  -1.119  -1.118  -1.063
300   A        -1.240  -1.239  -1.207  -1.059  -1.056  -1.005  -1.119  -1.118  -1.063
301   D        -1.240  -1.239  -1.207  -1.172  -1.169  -1.116  -1.119  -1.118  -1.063
302   V         1.329   1.330   1.349   1.445   1.445   1.474   1.392   1.392   1.415
303   R        -1.240  -1.239  -1.207  -1.300  -1.298  -1.243  -1.119  -1.118  -1.063
304   E         1.329   1.330   1.349   1.420   1.420   1.450   1.392   1.392   1.415
305   F         1.329   1.330   1.349   1.389   1.390   1.419   1.392   1.392   1.415
306   N        -0.159  -0.158  -0.205  -0.183  -0.180  -0.259  -0.282  -0.280  -0.352
307   T        -0.159  -0.158  -0.205   0.057   0.059  -0.008  -0.282  -0.280  -0.352
308   G        -0.159  -0.173  -0.206  -0.131  -0.158  -0.225  -0.282  -0.304  -0.352
309   H         1.329   1.330   1.349   1.500   1.500   1.529   1.392   1.392   1.415
310   N        -0.159  -0.158  -0.205  -0.137  -0.134  -0.205  -0.282  -0.280  -0.352
311   L        -0.159  -0.145  -0.201  -0.411  -0.382  -0.505  -0.282  -0.260  -0.345
312   L        -0.159  -0.173  -0.206  -0.426  -0.446  -0.481  -0.282  -0.304  -0.352
313   L        -1.240  -1.239  -1.207  -1.179  -1.170  -1.123  -1.119  -1.118  -1.063
314   E        -0.159  -0.158  -0.205  -0.098  -0.096  -0.179  -0.282  -0.280  -0.352
315   N        -1.240  -1.239  -1.207  -1.115  -1.113  -1.060  -1.119  -1.118  -1.063
316   P        -0.159  -0.173  -0.206  -0.126  -0.150  -0.201  -0.282  -0.304  -0.352
317   E        -1.240  -1.239  -1.207  -1.229  -1.230  -1.173  -1.119  -1.118  -1.063
318   D        -1.240  -1.239  -1.207  -1.096  -1.094  -1.041  -1.119  -1.118  -1.063
319   S        -0.159  -0.173  -0.206  -0.235  -0.258  -0.307  -0.282  -0.304  -0.352
320   F        -1.240  -1.239  -1.207  -1.048  -1.047  -0.994  -1.119  -1.118  -1.063
321   K        -0.159  -0.145  -0.201  -0.166  -0.141  -0.252  -0.282  -0.260  -0.345
322   C        -1.240  -1.239  -1.207  -1.059  -1.065  -1.005  -1.119  -1.118  -1.063
323   I         1.329   1.330   1.349   1.251   1.252   1.282   1.392   1.392   1.415
324   L        -1.240  -1.239  -1.207  -1.389  -1.380  -1.331  -1.119  -1.118  -1.063
325   N        -1.240  -1.239  -1.207  -1.360  -1.360  -1.303  -1.119  -1.118  -1.063
326   F         1.329   1.330   1.349   1.389   1.390   1.419   1.392   1.392   1.415
327   F        -0.159  -0.158  -0.205  -0.279  -0.276  -0.389  -0.282  -0.280  -0.352
328   A        -1.240  -1.239  -1.207  -1.296  -1.300  -1.239  -1.119  -1.118  -1.063
329   E        -0.292  -0.291  -0.264  -0.376  -0.376  -0.328  -0.491  -0.491  -0.444
330   E        -0.292  -0.291  -0.264  -0.376  -0.376  -0.328  -0.491  -0.491  -0.444
331   T        -0.292  -0.291  -0.264  -0.370  -0.369  -0.322  -0.491  -0.491  -0.444
332   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
333   D        -0.159  -0.145  -0.201  -0.075  -0.050  -0.151  -0.282  -0.260  -0.345
334   F        -1.240  -1.239  -1.207  -0.976  -0.972  -0.922  -1.119  -1.118  -1.063
335   E        -0.159  -0.158  -0.205  -0.019  -0.017  -0.087  -0.282  -0.280  -0.352
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P53208
Output conservation file - output/P53208
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
