1     M         1.771   1.795   1.970   2.004   2.039   2.299   1.978   2.015   2.304
2     T         0.098   0.127   0.258  -0.105  -0.068   0.082  -0.275  -0.235  -0.106
3     T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     V         0.128   0.010  -0.056   0.089  -0.067  -0.222   0.000  -0.146  -0.250
8     V        -0.113   0.018  -0.094  -0.274  -0.074  -0.237  -0.341  -0.156  -0.304
9     F         0.731   0.683   0.465   0.735   0.676   0.363   0.719   0.635   0.233
10    V         0.561   0.630   0.444   0.471   0.541   0.288   0.421   0.501   0.192
11    S         0.942   0.915   0.949   0.853   0.807   0.793   0.785   0.717   0.646
12    G         1.771   1.795   1.970   1.801   1.835   2.100   1.978   2.015   2.304
13    A         0.577   0.438   0.098   0.648   0.480   0.022   0.686   0.485  -0.014
14    T         0.810   0.815   0.914   0.629   0.629   0.722   0.520   0.509   0.567
15    G         1.771   1.795   1.970   1.801   1.835   2.100   1.978   2.015   2.304
16    F         1.771   1.795   1.970   1.817   1.850   2.115   1.978   2.015   2.304
17    I         0.810   0.920   0.982   0.647   0.833   0.868   0.520   0.726   0.719
18    A         1.365   1.255   1.194   1.297   1.182   1.119   1.514   1.338   1.164
19    L        -0.648  -0.651  -0.561  -0.779  -0.829  -0.700  -0.772  -0.792  -0.648
20    H         0.967   0.951   0.608   1.322   1.313   0.895   1.084   1.058   0.486
21    V         0.163   0.173   0.274   0.038   0.043   0.184  -0.209  -0.178  -0.083
22    V        -0.151  -0.208  -0.134  -0.351  -0.435  -0.371  -0.374  -0.428  -0.359
23    D        -0.362  -0.408  -0.479  -0.362  -0.480  -0.608  -0.441  -0.526  -0.564
24    D         0.561   0.541   0.426   0.709   0.689   0.467   0.421   0.390   0.157
25    L         1.771   1.795   1.970   1.657   1.695   1.959   1.978   2.015   2.304
26    L         1.365   1.347   1.199   1.338   1.330   1.165   1.514   1.486   1.174
27    K        -0.640  -0.697  -0.739  -0.784  -0.840  -0.851  -0.673  -0.718  -0.681
28    T        -0.848  -0.822  -0.995  -0.821  -0.826  -1.023  -0.706  -0.703  -0.788
29    G         0.967   1.022   0.606   1.163   1.228   0.721   1.084   1.157   0.484
30    Y         0.656   0.661   0.853   0.624   0.618   0.890   0.189   0.175   0.428
31    K        -1.281  -1.258  -1.104  -1.298  -1.249  -1.016  -1.103  -1.078  -0.880
32    V         1.771   1.795   1.970   1.687   1.714   1.988   1.978   2.015   2.304
33    I         0.191   0.097  -0.019   0.271   0.153  -0.026   0.089  -0.032  -0.198
34    G         1.365   1.307   1.191   1.479   1.421   1.281   1.514   1.422   1.158
35    S         1.365   1.354   1.197   1.412   1.413   1.228   1.514   1.496   1.169
36    G         0.440   0.487   0.403   0.299   0.383   0.257   0.189   0.284   0.103
37    R         1.771   1.795   1.970   1.940   1.971   2.236   1.978   2.015   2.304
38    S        -0.020   0.052  -0.313   0.223   0.321  -0.144   0.023   0.125  -0.345
39    Q        -1.157  -1.229  -1.106  -1.033  -1.110  -0.971  -1.004  -1.049  -0.879
40    E        -0.917  -0.823  -0.839  -0.893  -0.771  -0.821  -0.871  -0.779  -0.764
41    K         1.771   1.795   1.970   1.649   1.684   1.951   1.978   2.015   2.304
42    N         0.440   0.433   0.378   0.234   0.233   0.159   0.189   0.179   0.059
43    D        -0.859  -0.852  -0.829  -0.881  -0.894  -0.874  -0.838  -0.846  -0.761
44    G        -1.368  -1.444  -1.325  -1.062  -1.197  -1.080  -1.070  -1.122  -0.952
45    L         0.942   0.960   0.988   0.786   0.812   0.811   0.785   0.805   0.733
46    L        -1.587  -1.629  -1.520  -1.555  -1.601  -1.396  -1.170  -1.190  -1.013
47    K        -0.487  -0.492  -0.488  -0.657  -0.645  -0.602  -0.640  -0.638  -0.577
48    K        -0.226  -0.305  -0.417  -0.245  -0.362  -0.544  -0.242  -0.347  -0.480
49    F         0.080  -0.047  -0.054   0.091  -0.039  -0.071  -0.109  -0.240  -0.265
50    K        -0.552  -0.478  -0.486  -0.687  -0.556  -0.552  -0.706  -0.618  -0.573
51    S        -1.330  -1.327  -1.124  -1.383  -1.376  -1.071  -1.141  -1.127  -0.894
52    -        -0.816  -0.876  -0.826  -0.974  -1.085  -0.983  -0.818  -0.867  -0.754
53    -        -0.662  -0.705  -0.573  -0.732  -0.811  -0.622  -0.795  -0.826  -0.658
54    -        -1.159  -1.097  -0.901  -1.417  -1.326  -1.075  -1.103  -1.048  -0.818
55    N        -0.266  -0.305  -0.418  -0.235  -0.289  -0.428  -0.374  -0.411  -0.496
56    P        -0.532  -0.672  -0.945  -0.105  -0.289  -0.707  -0.308  -0.467  -0.725
57    N        -0.015  -0.040  -0.096  -0.068  -0.087  -0.191  -0.176  -0.191  -0.306
58    L         0.133   0.100  -0.007   0.177   0.147  -0.027   0.056   0.023  -0.178
59    S        -1.434  -1.393  -1.295  -1.397  -1.357  -1.256  -1.137  -1.100  -0.935
60    M        -0.487  -0.543  -0.498  -0.513  -0.548  -0.447  -0.640  -0.674  -0.585
61    E         0.731   0.615   0.452   0.776   0.593   0.320   0.719   0.505   0.208
62    I         0.163   0.192   0.319  -0.075  -0.060   0.126  -0.209  -0.203  -0.038
63    V         0.716   0.795   0.915   0.363   0.500   0.636   0.321   0.467   0.570
64    E        -1.032  -1.011  -0.858  -1.214  -1.189  -0.967  -1.004  -0.984  -0.786
65    D         1.771   1.795   1.970   1.763   1.794   2.063   1.978   2.015   2.304
66    I         0.656   0.679   0.857   0.335   0.356   0.603   0.189   0.215   0.437
67    A        -0.698  -0.703  -0.563  -0.728  -0.760  -0.555  -0.838  -0.836  -0.651
68    A        -1.376  -1.347  -1.299  -1.401  -1.378  -1.288  -1.103  -1.065  -0.937
69    P        -1.012  -1.107  -1.052  -0.943  -1.071  -1.047  -0.871  -0.941  -0.834
70    N        -1.128  -1.008  -1.053  -1.100  -0.965  -0.999  -1.004  -0.916  -0.844
71    A         0.626   0.652   0.852   0.170   0.199   0.490   0.123   0.156   0.426
72    F         1.120   1.159   1.093   1.186   1.239   1.111   1.117   1.176   0.958
73    D        -0.113   0.055  -0.081  -0.236   0.007  -0.177  -0.341  -0.125  -0.291
74    K        -1.165  -1.200  -1.259  -1.108  -1.186  -1.229  -0.905  -0.947  -0.905
75    V         0.041   0.137   0.237  -0.318  -0.168  -0.061  -0.374  -0.234  -0.140
76    F         0.561   0.422   0.383   0.591   0.363   0.250   0.421   0.186   0.077
77    Q        -0.603  -0.569  -0.507  -0.739  -0.704  -0.608  -0.772  -0.737  -0.605
78    K         0.927   0.833   0.560   0.964   0.858   0.488   1.027   0.883   0.406
79    H         1.771   1.795   1.970   1.949   1.985   2.245   1.978   2.015   2.304
80    G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
81    K        -0.436  -0.462  -0.486  -0.395  -0.410  -0.516  -0.532  -0.544  -0.565
82    E         0.010   0.006  -0.054  -0.116  -0.116  -0.169  -0.242  -0.245  -0.275
83    I         0.080  -0.013  -0.053   0.015  -0.104  -0.209  -0.109  -0.210  -0.265
84    K        -1.012  -1.025  -1.041  -1.025  -1.060  -1.087  -0.871  -0.885  -0.824
85    V        -0.024  -0.084  -0.076  -0.076  -0.177  -0.145  -0.308  -0.360  -0.304
86    V         0.010  -0.005  -0.060  -0.142  -0.156  -0.191  -0.242  -0.245  -0.277
87    L         0.577   0.496   0.110   0.741   0.662   0.222   0.686   0.565   0.003
88    H         1.771   1.795   1.970   1.949   1.985   2.245   1.978   2.015   2.304
89    I         0.731   0.622   0.448   0.796   0.644   0.360   0.719   0.527   0.200
90    A         1.771   1.795   1.970   1.615   1.652   1.917   1.978   2.015   2.304
91    S         1.771   1.795   1.970   1.752   1.782   2.052   1.978   2.015   2.304
92    P         1.771   1.795   1.970   1.838   1.876   2.136   1.978   2.015   2.304
93    V         0.967   1.018   0.620   1.163   1.222   0.711   1.084   1.151   0.507
94    H        -0.487  -0.405  -0.227  -0.575  -0.451  -0.221  -0.772  -0.682  -0.472
95    F         0.191   0.153  -0.010   0.388   0.325   0.139   0.089   0.032  -0.200
96    N        -0.573  -0.622  -0.723  -0.386  -0.458  -0.675  -0.507  -0.557  -0.648
97    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
98    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
99    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
100   T        -0.909  -0.883  -0.797  -1.085  -1.047  -0.942  -0.905  -0.871  -0.732
101   T        -0.028   0.026   0.212  -0.447  -0.352  -0.110  -0.474  -0.402  -0.182
102   D         0.731   0.828   0.573   0.831   0.954   0.630   0.719   0.865   0.428
103   F        -0.151  -0.177  -0.139  -0.172  -0.217  -0.190  -0.374  -0.412  -0.366
104   E        -0.015  -0.067  -0.117  -0.086  -0.187  -0.300  -0.176  -0.260  -0.332
105   K        -0.168  -0.302  -0.401  -0.170  -0.316  -0.492  -0.209  -0.339  -0.464
106   D        -0.113  -0.156  -0.077  -0.183  -0.226  -0.131  -0.341  -0.383  -0.299
107   L         0.129   0.226   0.341   0.006   0.118   0.303  -0.275  -0.135   0.004
108   L         0.967   0.871   0.589   1.012   0.911   0.536   1.084   0.943   0.455
109   I        -1.070  -1.050  -0.892  -1.154  -1.154  -0.943  -1.037  -1.019  -0.812
110   P         1.771   1.795   1.970   1.838   1.876   2.136   1.978   2.015   2.304
111   A         1.771   1.795   1.970   1.615   1.652   1.917   1.978   2.015   2.304
112   V        -0.015   0.082  -0.016  -0.094   0.042  -0.126  -0.176  -0.041  -0.200
113   N        -1.157  -1.102  -1.067  -1.037  -1.009  -0.907  -1.004  -0.969  -0.851
114   G         1.771   1.795   1.970   1.801   1.835   2.100   1.978   2.015   2.304
115   T         1.771   1.795   1.970   1.734   1.773   2.034   1.978   2.015   2.304
116   K        -0.698  -0.660  -0.550  -0.936  -0.888  -0.715  -0.838  -0.799  -0.641
117   S        -0.793  -0.798  -0.600  -1.016  -1.010  -0.764  -0.905  -0.904  -0.681
118   I         0.810   0.736   0.872   0.596   0.439   0.617   0.520   0.341   0.472
119   L         1.771   1.795   1.970   1.657   1.695   1.959   1.978   2.015   2.304
120   E         0.013   0.022   0.209  -0.308  -0.300  -0.034  -0.408  -0.406  -0.186
121   A        -0.695  -0.493  -0.718  -0.716  -0.449  -0.708  -0.673  -0.451  -0.646
122   I        -0.334  -0.314  -0.205  -0.648  -0.622  -0.480  -0.606  -0.586  -0.448
123   K        -0.323  -0.370  -0.435  -0.362  -0.406  -0.458  -0.474  -0.518  -0.522
124   N        -1.740  -1.733  -1.542  -1.690  -1.645  -1.393  -1.269  -1.252  -1.027
125   Y        -0.533  -0.595  -0.509  -0.384  -0.453  -0.352  -0.684  -0.726  -0.595
126   A         0.293   0.226   0.348  -0.028  -0.091   0.094  -0.109  -0.169  -0.003
127   A        -0.695  -0.724  -0.783  -0.594  -0.670  -0.760  -0.673  -0.716  -0.715
128   D        -0.168  -0.337  -0.420   0.029  -0.181  -0.325  -0.209  -0.395  -0.494
129   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
130   V         0.942   0.866   0.928   0.816   0.676   0.726   0.785   0.616   0.600
131   E        -0.599  -0.608  -0.727  -0.555  -0.555  -0.660  -0.606  -0.611  -0.663
132   K         0.344   0.309   0.358   0.274   0.201   0.280   0.123   0.025   0.038
133   V         0.561   0.613   0.432   0.509   0.549   0.319   0.421   0.469   0.164
134   V         1.365   1.432   1.210   1.368   1.439   1.210   1.514   1.612   1.194
135   I         0.440   0.503   0.400   0.342   0.444   0.262   0.189   0.294   0.103
136   T         1.771   1.795   1.970   1.734   1.773   2.034   1.978   2.015   2.304
137   S         1.771   1.795   1.970   1.752   1.782   2.052   1.978   2.015   2.304
138   S         1.771   1.795   1.970   1.752   1.782   2.052   1.978   2.015   2.304
139   V        -1.004  -0.923  -0.833  -1.007  -0.880  -0.785  -0.971  -0.884  -0.762
140   A         1.365   1.397   1.198   1.288   1.332   1.100   1.514   1.560   1.172
141   A         0.942   0.992   0.953   0.735   0.812   0.692   0.785   0.868   0.655
142   L        -0.323  -0.366  -0.417  -0.202  -0.258  -0.301  -0.474  -0.500  -0.501
143   A        -0.917  -0.980  -0.990  -0.740  -0.814  -0.817  -0.805  -0.836  -0.787
144   S        -0.909  -0.862  -0.826  -0.880  -0.847  -0.735  -0.905  -0.869  -0.759
145   P        -1.658  -1.603  -1.511  -1.527  -1.472  -1.307  -1.217  -1.173  -1.007
146   G        -1.556  -1.572  -1.335  -1.439  -1.441  -1.126  -1.217  -1.209  -0.961
147   D        -1.228  -1.169  -1.071  -1.209  -1.147  -0.965  -1.065  -1.014  -0.855
148   M        -2.110  -2.047  -1.877  -1.787  -1.709  -1.522  -1.369  -1.325  -1.110
149   K        -1.682  -1.696  -1.521  -1.489  -1.520  -1.275  -1.236  -1.232  -1.015
150   D         0.967   0.821   0.592   1.140   0.982   0.705   1.084   0.867   0.460
151   T        -0.020  -0.153  -0.379   0.258   0.095  -0.300   0.023  -0.138  -0.435
152   S        -0.188  -0.143  -0.122  -0.343  -0.271  -0.229  -0.474  -0.414  -0.359
153   F        -1.529  -1.537  -1.345  -1.393  -1.414  -1.207  -1.203  -1.191  -0.968
154   V        -0.276  -0.257  -0.155  -0.545  -0.512  -0.351  -0.573  -0.539  -0.397
155   V        -1.587  -1.536  -1.351  -1.523  -1.448  -1.171  -1.236  -1.193  -0.972
156   N        -0.151  -0.163  -0.128  -0.250  -0.248  -0.239  -0.374  -0.375  -0.354
157   E         1.771   1.795   1.970   1.734   1.771   2.034   1.978   2.015   2.304
158   E        -0.906  -0.874  -0.990  -0.834  -0.813  -0.984  -0.739  -0.712  -0.776
159   S        -0.235  -0.235  -0.147  -0.408  -0.409  -0.285  -0.507  -0.503  -0.387
160   W         1.771   1.795   1.970   2.004   2.040   2.299   1.978   2.015   2.304
161   N         1.771   1.795   1.970   1.795   1.829   2.093   1.978   2.015   2.304
162   K         0.197   0.139  -0.303   0.561   0.496  -0.118   0.321   0.246  -0.328
163   D        -0.276  -0.220  -0.122  -0.411  -0.341  -0.175  -0.573  -0.496  -0.357
164   T         0.731   0.744   0.495   0.801   0.811   0.462   0.719   0.718   0.286
165   W         0.133   0.061  -0.049   0.537   0.436   0.258   0.056  -0.052  -0.236
166   E         0.191   0.199  -0.026   0.245   0.253  -0.059   0.089   0.090  -0.221
167   S        -0.235  -0.268  -0.179  -0.276  -0.345  -0.248  -0.507  -0.553  -0.430
168   C         0.577   0.499   0.103   0.681   0.601   0.123   0.686   0.577  -0.007
169   Q        -0.573  -0.704  -0.767  -0.474  -0.658  -0.731  -0.507  -0.653  -0.693
170   A        -1.166  -1.286  -1.268  -0.910  -1.089  -1.137  -0.875  -0.973  -0.907
171   -         0.279   0.130   0.274   0.079  -0.167   0.013  -0.002  -0.232  -0.082
172   -         0.364   0.283   0.290   0.357   0.183   0.169   0.137  -0.035  -0.064
173   N         0.942   0.972   0.943   0.916   0.958   0.841   0.785   0.828   0.633
174   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
175   A        -0.695  -0.645  -0.765  -0.599  -0.559  -0.771  -0.673  -0.643  -0.703
176   V        -1.004  -0.992  -0.847  -1.108  -1.125  -0.897  -0.971  -0.963  -0.773
177   S        -0.947  -0.976  -0.856  -1.217  -1.261  -1.088  -0.938  -0.956  -0.784
178   A        -0.446  -0.326  -0.433  -0.597  -0.407  -0.549  -0.573  -0.412  -0.504
179   Y         1.771   1.795   1.970   1.957   1.989   2.253   1.978   2.015   2.304
180   C        -1.368  -1.354  -1.297  -1.059  -1.033  -0.915  -1.070  -1.070  -0.936
181   G         0.626   0.650   0.849   0.224   0.247   0.537   0.123   0.150   0.419
182   S         1.365   1.347   1.199   1.421   1.404   1.220   1.514   1.486   1.174
183   K         1.771   1.795   1.970   1.649   1.684   1.951   1.978   2.015   2.304
184   K        -0.446  -0.312  -0.443  -0.639  -0.475  -0.642  -0.573  -0.449  -0.527
185   F        -0.113  -0.111  -0.124  -0.053  -0.082  -0.064  -0.341  -0.344  -0.347
186   A         1.771   1.795   1.970   1.615   1.652   1.917   1.978   2.015   2.304
187   E         1.771   1.795   1.970   1.734   1.771   2.034   1.978   2.015   2.304
188   K         0.577   0.496   0.110   0.713   0.617   0.158   0.686   0.565   0.003
189   T         0.133   0.189   0.016   0.050   0.141  -0.146   0.056   0.139  -0.134
190   A         0.561   0.709   0.491   0.435   0.644   0.352   0.421   0.655   0.279
191   W        -0.020   0.038  -0.324   0.428   0.521  -0.015   0.023   0.100  -0.358
192   D         0.357   0.395   0.383   0.170   0.228   0.222   0.023   0.079   0.067
193   F         1.120   1.060   1.009   1.232   1.152   1.061   1.117   0.996   0.779
194   L        -0.515  -0.363  -0.683  -0.412  -0.222  -0.602  -0.474  -0.301  -0.612
195   E        -0.487  -0.426  -0.458  -0.640  -0.548  -0.539  -0.640  -0.568  -0.545
196   E        -1.223  -1.129  -1.082  -1.182  -1.087  -0.958  -1.070  -0.999  -0.866
197   N        -0.341  -0.448  -0.446  -0.398  -0.506  -0.484  -0.507  -0.590  -0.532
198   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
199   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
200   S         0.357   0.339   0.352   0.108   0.082   0.130   0.023  -0.009   0.011
201   I        -0.015  -0.062  -0.122   0.045  -0.028  -0.176  -0.176  -0.239  -0.339
202   K        -1.492  -1.390  -1.298  -1.366  -1.259  -1.078  -1.170  -1.092  -0.934
203   F         1.120   1.060   1.009   1.232   1.152   1.061   1.117   0.996   0.779
204   T        -1.215  -1.189  -1.093  -1.184  -1.187  -1.050  -1.037  -1.025  -0.869
205   L         0.810   0.840   0.932   0.567   0.611   0.707   0.520   0.562   0.608
206   S         0.350   0.147  -0.010   0.492   0.251  -0.014   0.355   0.080  -0.181
207   T         0.440   0.506   0.438   0.411   0.528   0.423   0.189   0.324   0.180
208   I         0.626   0.650   0.849   0.252   0.278   0.579   0.123   0.150   0.419
209   N         1.771   1.795   1.970   1.795   1.829   2.093   1.978   2.015   2.304
210   P         1.771   1.795   1.970   1.838   1.876   2.136   1.978   2.015   2.304
211   G        -0.974  -0.928  -0.847  -1.132  -1.046  -0.944  -0.971  -0.923  -0.779
212   F        -0.420  -0.450  -0.485  -0.181  -0.212  -0.352  -0.474  -0.505  -0.557
213   V         0.810   0.920   0.982   0.596   0.767   0.827   0.520   0.726   0.719
214   F         0.561   0.538   0.465   0.615   0.632   0.489   0.421   0.419   0.231
215   G         1.771   1.795   1.970   1.801   1.835   2.100   1.978   2.015   2.304
216   P         1.771   1.795   1.970   1.838   1.876   2.136   1.978   2.015   2.304
217   Q        -0.786  -0.862  -0.807  -0.608  -0.678  -0.606  -0.805  -0.852  -0.739
218   L        -0.859  -0.860  -0.806  -0.965  -0.981  -0.965  -0.838  -0.834  -0.738
219   F        -0.698  -0.666  -0.568  -0.825  -0.750  -0.619  -0.838  -0.807  -0.655
220   A        -1.039  -1.052  -0.877  -1.193  -1.187  -0.939  -1.004  -1.003  -0.798
221   D        -1.157  -1.199  -1.086  -1.117  -1.149  -0.977  -1.004  -1.025  -0.862
222   S        -0.573  -0.728  -0.767  -0.423  -0.658  -0.797  -0.507  -0.666  -0.690
223   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
224   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
225   R        -1.107  -1.050  -0.887  -1.133  -1.058  -0.842  -1.070  -1.023  -0.810
226   N        -1.339  -1.357  -1.278  -1.322  -1.341  -1.234  -1.070  -1.074  -0.923
227   G        -0.341  -0.340  -0.425  -0.501  -0.471  -0.523  -0.507  -0.489  -0.511
228   I         0.810   0.826   0.902   0.567   0.587   0.649   0.520   0.533   0.539
229   N         1.771   1.795   1.970   1.795   1.829   2.093   1.978   2.015   2.304
230   S         0.967   1.018   0.620   1.081   1.148   0.635   1.084   1.151   0.507
231   S         1.771   1.795   1.970   1.752   1.782   2.052   1.978   2.015   2.304
232   S         0.344   0.391   0.382   0.294   0.352   0.265   0.123   0.176   0.081
233   A        -0.446  -0.456  -0.475  -0.477  -0.478  -0.496  -0.573  -0.576  -0.558
234   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
235   I        -0.552  -0.513  -0.475  -0.685  -0.600  -0.530  -0.706  -0.646  -0.563
236   I         0.080   0.071  -0.030   0.046   0.059  -0.101  -0.109  -0.100  -0.229
237   A        -0.859  -0.851  -0.824  -0.876  -0.844  -0.859  -0.838  -0.825  -0.755
238   N        -1.434  -1.422  -1.293  -1.320  -1.327  -1.145  -1.137  -1.120  -0.935
239   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
240   L        -0.235  -0.216  -0.146  -0.604  -0.591  -0.473  -0.507  -0.495  -0.385
241   V         0.350   0.270   0.008   0.409   0.279  -0.082   0.355   0.208  -0.160
242   S        -1.070  -1.016  -0.889  -1.208  -1.139  -0.931  -1.037  -0.990  -0.811
243   Y        -0.859  -0.905  -0.836  -0.876  -0.949  -0.857  -0.838  -0.884  -0.763
244   K         0.350   0.267   0.079   0.395   0.308   0.035   0.355   0.253  -0.042
245   L        -0.362  -0.397  -0.462  -0.274  -0.317  -0.458  -0.441  -0.481  -0.542
246   G        -0.362  -0.457  -0.488  -0.297  -0.447  -0.534  -0.441  -0.552  -0.568
247   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
248   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
249   D        -0.510  -0.456  -0.464  -0.489  -0.411  -0.421  -0.646  -0.570  -0.543
250   N        -1.454  -1.417  -1.319  -1.358  -1.294  -1.242  -1.141  -1.098  -0.950
251   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
252   F        -0.763  -0.859  -0.803  -0.690  -0.821  -0.778  -0.772  -0.844  -0.738
253   Y        -1.951  -1.874  -1.716  -1.799  -1.680  -1.504  -1.335  -1.280  -1.071
254   N        -1.434  -1.448  -1.314  -1.275  -1.288  -1.147  -1.137  -1.133  -0.946
255   Y        -1.682  -1.627  -1.522  -1.442  -1.386  -1.261  -1.236  -1.191  -1.015
256   S        -0.226  -0.324  -0.436  -0.233  -0.358  -0.548  -0.242  -0.362  -0.503
257   G        -0.379  -0.466  -0.697  -0.035  -0.144  -0.461  -0.275  -0.378  -0.614
258   P        -1.951  -1.897  -1.710  -1.571  -1.512  -1.266  -1.335  -1.293  -1.069
259   F        -0.487  -0.509  -0.451  -0.341  -0.338  -0.209  -0.640  -0.650  -0.539
260   I         0.344   0.348   0.367   0.280   0.247   0.268   0.123   0.097   0.056
261   D         1.771   1.795   1.970   1.763   1.794   2.063   1.978   2.015   2.304
262   V         1.771   1.795   1.970   1.687   1.714   1.988   1.978   2.015   2.304
263   R         1.771   1.795   1.970   1.940   1.971   2.236   1.978   2.015   2.304
264   D         1.365   1.389   1.202   1.445   1.476   1.274   1.514   1.549   1.179
265   V         0.810   0.920   0.982   0.681   0.836   0.924   0.520   0.726   0.719
266   S         1.365   1.354   1.197   1.293   1.291   1.112   1.514   1.496   1.169
267   K         0.010  -0.012  -0.056  -0.102  -0.134  -0.153  -0.242  -0.264  -0.277
268   A         0.731   0.816   0.567   0.666   0.785   0.453   0.719   0.848   0.417
269   H         1.771   1.795   1.970   1.949   1.985   2.245   1.978   2.015   2.304
270   L        -0.073  -0.084  -0.140  -0.146  -0.178  -0.334  -0.209  -0.234  -0.353
271   L        -1.157  -1.208  -1.092  -1.153  -1.178  -1.005  -1.004  -1.021  -0.870
272   A         1.120   1.200   1.160   1.011   1.120   1.076   1.117   1.246   1.095
273   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
274   F         0.196   0.214   0.276  -0.015   0.005   0.056  -0.109  -0.096  -0.074
275   E        -1.157  -0.945  -1.037  -1.132  -0.835  -0.948  -1.004  -0.810  -0.820
276   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
277   P        -1.012  -1.041  -1.046  -0.879  -0.923  -0.958  -0.871  -0.887  -0.829
278   E        -0.170  -0.138  -0.132  -0.408  -0.387  -0.349  -0.441  -0.421  -0.368
279   C        -0.610  -0.630  -0.547  -0.769  -0.793  -0.677  -0.739  -0.747  -0.633
280   A        -0.848  -1.015  -1.043  -0.667  -0.896  -1.000  -0.706  -0.848  -0.825
281   G        -0.170  -0.096  -0.096  -0.218  -0.141  -0.093  -0.441  -0.367  -0.328
282   Q        -0.575  -0.570  -0.492  -0.596  -0.586  -0.453  -0.739  -0.719  -0.586
283   R         1.771   1.795   1.970   1.940   1.971   2.236   1.978   2.015   2.304
284   L         0.967   0.839   0.590   1.037   0.909   0.614   1.084   0.892   0.457
285   F        -0.276  -0.241  -0.157  -0.402  -0.350  -0.177  -0.573  -0.522  -0.401
286   L         0.350   0.231   0.059   0.410   0.274   0.006   0.355   0.206  -0.071
287   C        -1.070  -1.042  -1.053  -0.749  -0.759  -0.833  -0.905  -0.897  -0.836
288   E        -1.128  -1.187  -1.085  -1.186  -1.278  -1.153  -1.004  -1.034  -0.865
289   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
290   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
291   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
292   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
293   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
294   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
295   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
296   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
297   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
298   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
299   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
300   D        -0.209  -0.076  -0.143  -0.273  -0.059  -0.253  -0.408  -0.227  -0.359
301   M        -0.532  -0.710  -0.965  -0.231  -0.461  -0.805  -0.308  -0.511  -0.744
302   F         0.967   1.092   0.629   1.186   1.322   0.790   1.084   1.255   0.522
303   C        -0.599  -0.649  -0.539  -0.404  -0.523  -0.459  -0.673  -0.741  -0.618
304   S        -0.706  -0.663  -0.544  -0.842  -0.787  -0.664  -0.805  -0.763  -0.628
305   Q         0.350   0.231   0.059   0.658   0.531   0.249   0.355   0.206  -0.071
306   E        -0.573  -0.608  -0.749  -0.375  -0.430  -0.622  -0.507  -0.551  -0.675
307   A        -0.266  -0.258  -0.406  -0.241  -0.223  -0.410  -0.374  -0.358  -0.487
308   L        -0.362  -0.449  -0.448  -0.428  -0.503  -0.555  -0.441  -0.511  -0.518
309   D        -0.226  -0.305  -0.403  -0.051  -0.154  -0.343  -0.242  -0.320  -0.460
310   I         0.350   0.251  -0.003   0.531   0.384   0.005   0.355   0.206  -0.175
311   L        -0.698  -0.631  -0.546  -0.959  -0.884  -0.709  -0.838  -0.775  -0.634
312   N         1.120   0.997   1.002   1.207   1.038   1.022   1.117   0.877   0.764
313   E        -0.323  -0.252  -0.408  -0.426  -0.332  -0.440  -0.474  -0.390  -0.492
314   E        -0.453  -0.448  -0.253  -0.767  -0.763  -0.489  -0.733  -0.732  -0.502
315   F        -0.151   0.037  -0.074  -0.219   0.073  -0.129  -0.374  -0.119  -0.272
316   P         1.365   1.389   1.202   1.517   1.554   1.337   1.514   1.549   1.179
317   Q        -0.015  -0.086  -0.111  -0.003  -0.086  -0.150  -0.176  -0.257  -0.326
318   L        -0.226  -0.318  -0.412  -0.161  -0.265  -0.426  -0.242  -0.336  -0.468
319   K        -0.379  -0.433  -0.681  -0.172  -0.250  -0.560  -0.275  -0.344  -0.597
320   G         1.120   0.997   1.002   1.186   1.004   0.963   1.117   0.877   0.764
321   K         0.577   0.533   0.130   0.681   0.621   0.099   0.686   0.612   0.031
322   I         1.365   1.307   1.191   1.459   1.395   1.250   1.514   1.422   1.158
323   A         0.344   0.353   0.367   0.170   0.167   0.160   0.123   0.106   0.057
324   T        -0.821  -0.757  -0.568  -1.042  -0.951  -0.705  -0.938  -0.872  -0.656
325   G         0.577   0.493   0.112   0.852   0.754   0.265   0.686   0.560   0.007
326   E        -1.434  -1.385  -1.287  -1.345  -1.297  -1.161  -1.137  -1.095  -0.929
327   P         0.350   0.231   0.059   0.579   0.442   0.154   0.355   0.206  -0.071
328   G        -0.753  -0.739  -0.760  -0.694  -0.668  -0.779  -0.706  -0.687  -0.686
329   S        -1.281  -1.235  -1.086  -1.304  -1.234  -1.037  -1.103  -1.052  -0.863
330   G        -0.909  -0.933  -0.817  -0.820  -0.869  -0.723  -0.905  -0.909  -0.748
331   S        -1.070  -1.120  -1.081  -1.019  -1.119  -1.113  -0.905  -0.959  -0.860
332   T        -1.166  -1.208  -1.099  -1.287  -1.318  -1.124  -1.027  -1.044  -0.875
333   F        -1.260  -1.297  -1.294  -1.131  -1.218  -1.203  -0.989  -1.020  -0.931
334   L        -0.826  -0.888  -1.033  -0.694  -0.799  -1.057  -0.646  -0.725  -0.813
335   T        -1.392  -1.397  -1.275  -1.443  -1.443  -1.272  -1.103  -1.091  -0.920
336   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
337   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
338   N        -1.281  -1.226  -1.115  -1.295  -1.227  -1.036  -1.103  -1.065  -0.889
339   C        -1.650  -1.641  -1.653  -1.293  -1.278  -1.324  -1.103  -1.098  -1.029
340   C        -0.859  -0.727  -0.793  -0.787  -0.615  -0.709  -0.838  -0.711  -0.726
341   K        -0.974  -0.876  -0.814  -0.949  -0.855  -0.738  -0.971  -0.877  -0.748
342   C        -1.339  -1.342  -1.150  -1.047  -1.077  -0.833  -1.137  -1.128  -0.912
343   D         0.350   0.407   0.097   0.547   0.620   0.224   0.355   0.438  -0.016
344   N         0.197   0.353  -0.250   0.532   0.705  -0.037   0.321   0.512  -0.262
345   R        -0.648  -0.644  -0.552  -0.786  -0.783  -0.656  -0.772  -0.762  -0.639
346   K        -1.836  -1.771  -1.678  -1.755  -1.698  -1.532  -1.269  -1.223  -1.051
347   T         0.942   0.903   0.921   0.853   0.785   0.737   0.785   0.691   0.584
348   K        -0.786  -0.713  -0.744  -0.763  -0.675  -0.695  -0.805  -0.738  -0.686
349   N        -0.859  -0.950  -0.830  -0.883  -1.003  -0.839  -0.838  -0.916  -0.760
350   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
351   L         0.520   0.563   0.109   0.614   0.669   0.057   0.609   0.660   0.002
352   L         0.731   0.828   0.573   0.725   0.857   0.534   0.719   0.865   0.428
353   G        -0.736  -0.661  -0.546  -0.906  -0.795  -0.636  -0.871  -0.793  -0.633
354   F        -0.399  -0.307  -0.206  -0.556  -0.420  -0.275  -0.673  -0.563  -0.444
355   Q        -0.793  -0.751  -0.565  -0.974  -0.918  -0.675  -0.905  -0.863  -0.652
356   F        -0.188  -0.188  -0.155  -0.106  -0.117  -0.048  -0.474  -0.479  -0.395
357   N        -0.362  -0.450  -0.475  -0.193  -0.302  -0.342  -0.441  -0.536  -0.552
358   K        -0.698  -0.672  -0.542  -0.827  -0.799  -0.608  -0.838  -0.807  -0.629
359   F         0.191   0.053  -0.022   0.166   0.006  -0.141   0.089  -0.071  -0.218
360   R        -0.226  -0.059  -0.398  -0.052   0.157  -0.283  -0.242  -0.045  -0.457
361   D        -0.698  -0.681  -0.563  -0.817  -0.795  -0.594  -0.838  -0.826  -0.652
362   C        -0.446  -0.554  -0.496  -0.410  -0.515  -0.415  -0.573  -0.675  -0.584
363   I         0.357   0.280   0.369   0.160   0.080   0.228   0.023  -0.061   0.034
364   V        -0.947  -0.828  -0.819  -0.999  -0.835  -0.814  -0.938  -0.815  -0.749
365   D         1.771   1.795   1.970   1.763   1.794   2.063   1.978   2.015   2.304
366   T         0.163   0.192   0.319  -0.047  -0.042   0.129  -0.209  -0.203  -0.038
367   A         0.098   0.114   0.236  -0.299  -0.292  -0.143  -0.275  -0.268  -0.144
368   S        -0.420  -0.368  -0.492  -0.502  -0.425  -0.685  -0.474  -0.407  -0.567
369   Q         0.577   0.438   0.098   0.938   0.771   0.281   0.686   0.485  -0.014
370   L        -0.399  -0.410  -0.232  -0.391  -0.465  -0.228  -0.673  -0.695  -0.482
371   L        -0.726  -0.791  -0.976  -0.512  -0.598  -0.855  -0.540  -0.613  -0.757
372   E        -0.695  -0.580  -0.729  -0.668  -0.500  -0.751  -0.673  -0.545  -0.657
373   V        -1.682  -1.648  -1.516  -1.435  -1.403  -1.202  -1.236  -1.205  -1.012
374   Q        -1.494  -1.531  -1.332  -1.388  -1.433  -1.148  -1.179  -1.188  -0.960
375   S        -1.039  -1.024  -0.856  -1.186  -1.155  -0.884  -1.004  -0.980  -0.779
376   K        -0.594  -0.559  -0.515  -0.635  -0.563  -0.540  -0.691  -0.634  -0.585
377   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
378   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
379   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
380   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
381   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
382   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
383   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
384   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
385   S        -1.645  -1.598  -1.508  -1.609  -1.578  -1.465  -1.203  -1.159  -1.005
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P53183
Output conservation file - output/P53183
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
