1     M         2.141   2.195   2.233   2.460   2.558   2.622   2.419   2.501   2.569
2     A        -0.469  -0.402  -0.452  -0.532  -0.436  -0.495  -0.514  -0.413  -0.477
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
19    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
20    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
21    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
22    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
23    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
24    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
25    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
26    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
27    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
28    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
29    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
30    E        -1.339  -1.318  -1.298  -1.301  -1.226  -1.232  -1.100  -1.062  -1.026
31    T         0.729   0.759   0.670   0.827   0.876   0.720   0.659   0.705   0.542
32    S        -0.617  -0.603  -0.565  -0.729  -0.680  -0.646  -0.709  -0.681  -0.627
33    N        -0.617  -0.603  -0.565  -0.768  -0.764  -0.686  -0.709  -0.681  -0.627
34    D         0.543   0.529   0.549   0.231   0.194   0.213   0.333   0.300   0.322
35    P         0.543   0.529   0.549   0.654   0.613   0.632   0.333   0.300   0.322
36    F        -0.469  -0.485  -0.484  -0.378  -0.378  -0.421  -0.514  -0.531  -0.521
37    L        -1.339  -1.318  -1.298  -1.428  -1.386  -1.362  -1.100  -1.062  -1.026
38    S        -1.339  -1.318  -1.298  -1.184  -1.125  -1.112  -1.100  -1.062  -1.026
39    Y        -0.469  -0.485  -0.484  -0.116  -0.114  -0.117  -0.514  -0.531  -0.521
40    V        -0.469  -0.484  -0.488  -0.645  -0.662  -0.651  -0.514  -0.529  -0.525
41    L        -0.469  -0.402  -0.452  -0.508  -0.378  -0.493  -0.514  -0.413  -0.477
42    S         0.729   0.843   0.699   0.623   0.786   0.585   0.659   0.847   0.593
43    S         0.543   0.528   0.521   0.372   0.348   0.342   0.333   0.298   0.271
44    K         2.141   2.195   2.233   2.064   2.149   2.217   2.419   2.501   2.569
45    Q        -0.617  -0.603  -0.565  -0.926  -0.914  -0.847  -0.709  -0.681  -0.627
46    L         0.543   0.600   0.546   0.403   0.506   0.372   0.333   0.428   0.317
47    T         0.543   0.592   0.549   0.764   0.851   0.792   0.333   0.413   0.322
48    N         2.141   2.195   2.233   2.393   2.485   2.553   2.419   2.501   2.569
49    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
50    N         0.729   0.626   0.629   0.985   0.827   0.860   0.659   0.474   0.468
51    R        -1.339  -1.318  -1.298  -1.089  -1.024  -1.014  -1.100  -1.062  -1.026
52    L        -0.469  -0.342  -0.452  -0.324  -0.108  -0.293  -0.514  -0.331  -0.478
53    R         0.729   0.626   0.629   0.975   0.819   0.820   0.659   0.474   0.468
54    R        -0.469  -0.533  -0.513  -0.364  -0.471  -0.464  -0.514  -0.591  -0.559
55    K        -1.339  -1.318  -1.298  -1.432  -1.359  -1.366  -1.100  -1.062  -1.026
56    A         0.729   0.626   0.629   0.836   0.667   0.655   0.659   0.474   0.468
57    V        -1.339  -1.318  -1.298  -1.340  -1.362  -1.272  -1.100  -1.062  -1.026
58    T        -1.339  -1.318  -1.298  -1.218  -1.191  -1.146  -1.100  -1.062  -1.026
59    K        -0.469  -0.402  -0.452  -0.407  -0.270  -0.389  -0.514  -0.413  -0.477
60    Q        -0.617  -0.603  -0.565  -0.621  -0.604  -0.535  -0.709  -0.681  -0.627
61    L         0.543   0.529   0.549   0.118   0.085   0.120   0.333   0.300   0.322
62    G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
63    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
64    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
65    D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
66    D         0.729   0.626   0.629   0.682   0.519   0.534   0.659   0.474   0.468
67    N        -0.469  -0.342  -0.452  -0.460  -0.278  -0.422  -0.514  -0.331  -0.478
68    K        -1.339  -1.318  -1.298  -1.100  -1.071  -1.026  -1.100  -1.062  -1.026
69    V        -0.469  -0.533  -0.513  -0.304  -0.383  -0.374  -0.514  -0.591  -0.559
70    S         0.729   0.843   0.699   0.580   0.752   0.532   0.659   0.847   0.593
71    E        -1.339  -1.318  -1.298  -1.337  -1.294  -1.268  -1.100  -1.062  -1.026
72    E        -0.617  -0.603  -0.565  -0.664  -0.645  -0.579  -0.709  -0.681  -0.627
73    F        -0.617  -0.603  -0.565  -0.825  -0.827  -0.743  -0.709  -0.681  -0.627
74    L        -0.617  -0.603  -0.565  -0.988  -0.946  -0.911  -0.709  -0.681  -0.627
75    R         0.543   0.529   0.549   0.468   0.424   0.434   0.333   0.300   0.322
76    Y         0.729   0.626   0.629   0.962   0.804   0.808   0.659   0.474   0.468
77    Q        -0.469  -0.485  -0.484  -0.463  -0.486  -0.501  -0.514  -0.531  -0.521
78    H        -1.339  -1.318  -1.298  -1.015  -0.963  -0.938  -1.100  -1.062  -1.026
79    T        -1.339  -1.318  -1.298  -1.177  -1.163  -1.104  -1.100  -1.062  -1.026
80    Y        -0.469  -0.533  -0.513  -0.192  -0.274  -0.251  -0.514  -0.591  -0.559
81    Q        -0.469  -0.484  -0.488  -0.544  -0.568  -0.557  -0.514  -0.529  -0.525
82    R         0.401   0.431   0.471   0.255   0.300   0.358   0.073   0.118   0.177
83    E        -0.469  -0.402  -0.452  -0.520  -0.403  -0.506  -0.514  -0.413  -0.477
84    A        -1.339  -1.318  -1.298  -1.244  -1.167  -1.173  -1.100  -1.062  -1.026
85    F        -0.469  -0.533  -0.513  -0.301  -0.391  -0.385  -0.514  -0.591  -0.559
86    E        -0.469  -0.533  -0.513  -0.624  -0.745  -0.730  -0.514  -0.591  -0.559
87    Y         0.401   0.443   0.479   0.395   0.473   0.524   0.073   0.141   0.194
88    L        -0.469  -0.342  -0.452  -0.831  -0.612  -0.822  -0.514  -0.331  -0.478
89    Q        -0.469  -0.484  -0.488  -0.608  -0.631  -0.632  -0.514  -0.529  -0.525
90    T        -0.469  -0.402  -0.452  -0.511  -0.412  -0.479  -0.514  -0.413  -0.477
91    K        -1.339  -1.318  -1.298  -1.210  -1.199  -1.138  -1.100  -1.062  -1.026
92    H        -1.339  -1.318  -1.298  -1.068  -1.091  -0.992  -1.100  -1.062  -1.026
93    D        -0.469  -0.484  -0.488  -0.831  -0.902  -0.892  -0.514  -0.529  -0.525
94    A        -0.469  -0.402  -0.452  -0.743  -0.655  -0.714  -0.514  -0.413  -0.477
95    H        -1.339  -1.318  -1.298  -1.158  -1.099  -1.085  -1.100  -1.062  -1.026
96    K         0.401   0.443   0.479  -0.015   0.041   0.104   0.073   0.141   0.194
97    I        -1.339  -1.318  -1.298  -1.609  -1.619  -1.547  -1.100  -1.062  -1.026
98    M         0.401   0.443   0.479   0.185   0.201   0.271   0.073   0.141   0.194
99    E        -0.469  -0.533  -0.513  -0.514  -0.616  -0.595  -0.514  -0.591  -0.559
100   S        -1.339  -1.318  -1.298  -1.420  -1.351  -1.354  -1.100  -1.062  -1.026
101   Q        -0.469  -0.342  -0.452  -0.535  -0.321  -0.506  -0.514  -0.331  -0.478
102   Y         2.141   2.195   2.233   2.319   2.414   2.478   2.419   2.501   2.569
103   E        -0.617  -0.603  -0.565  -0.701  -0.687  -0.616  -0.709  -0.681  -0.627
104   Q        -1.339  -1.318  -1.298  -1.344  -1.316  -1.276  -1.100  -1.062  -1.026
105   Y         2.141   2.195   2.233   2.335   2.435   2.495   2.419   2.501   2.569
106   Q        -0.469  -0.485  -0.484  -0.425  -0.443  -0.457  -0.514  -0.531  -0.521
107   S        -0.469  -0.533  -0.513  -0.583  -0.679  -0.639  -0.514  -0.591  -0.559
108   S         0.729   0.626   0.629   0.545   0.361   0.365   0.659   0.474   0.468
109   S        -1.339  -1.318  -1.298  -1.412  -1.371  -1.345  -1.100  -1.062  -1.026
110   K         0.729   0.626   0.629   0.566   0.365   0.358   0.659   0.474   0.468
111   T        -1.339  -1.318  -1.298  -1.086  -1.080  -1.011  -1.100  -1.062  -1.026
112   R         2.141   2.195   2.233   2.348   2.451   2.508   2.419   2.501   2.569
113   R         0.729   0.626   0.629   0.935   0.772   0.764   0.659   0.474   0.468
114   Y         0.729   0.626   0.629   1.059   0.937   0.943   0.659   0.474   0.468
115   S         0.729   0.626   0.629   0.625   0.467   0.478   0.659   0.474   0.468
116   I        -1.339  -1.318  -1.298  -1.340  -1.325  -1.272  -1.100  -1.062  -1.026
117   D         0.729   0.626   0.629   0.582   0.396   0.393   0.659   0.474   0.468
118   L        -0.469  -0.484  -0.488  -0.399  -0.417  -0.451  -0.514  -0.529  -0.525
119   D         0.729   0.626   0.629   0.677   0.522   0.528   0.659   0.474   0.468
120   S        -1.339  -1.318  -1.298  -1.180  -1.117  -1.108  -1.100  -1.062  -1.026
121   V         0.729   0.845   0.688   0.903   1.083   0.848   0.659   0.851   0.574
122   D        -1.339  -1.318  -1.298  -0.901  -0.851  -0.822  -1.100  -1.062  -1.026
123   A        -1.339  -1.318  -1.298  -1.388  -1.405  -1.321  -1.100  -1.062  -1.026
124   V        -0.469  -0.485  -0.484  -0.378  -0.394  -0.411  -0.514  -0.531  -0.521
125   D        -0.469  -0.404  -0.448  -0.439  -0.330  -0.395  -0.514  -0.415  -0.472
126   T        -1.339  -1.318  -1.298  -1.233  -1.199  -1.162  -1.100  -1.062  -1.026
127   E        -1.339  -1.318  -1.298  -1.225  -1.148  -1.154  -1.100  -1.062  -1.026
128   S        -0.469  -0.533  -0.513  -0.630  -0.733  -0.695  -0.514  -0.591  -0.559
129   Q        -0.469  -0.342  -0.452  -0.502  -0.273  -0.476  -0.514  -0.331  -0.478
130   T        -0.469  -0.404  -0.448  -0.439  -0.321  -0.411  -0.514  -0.415  -0.472
131   E        -0.617  -0.603  -0.565  -0.702  -0.661  -0.618  -0.709  -0.681  -0.627
132   Y        -0.617  -0.603  -0.565  -0.521  -0.494  -0.432  -0.709  -0.681  -0.627
133   P         0.543   0.587   0.578   0.476   0.549   0.543   0.333   0.405   0.377
134   N        -0.617  -0.603  -0.565  -0.713  -0.703  -0.629  -0.709  -0.681  -0.627
135   E        -0.617  -0.603  -0.565  -0.642  -0.616  -0.557  -0.709  -0.681  -0.627
136   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
137   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
138   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
139   E         0.543   0.604   0.582   0.390   0.498   0.441   0.333   0.434   0.384
140   F        -0.617  -0.603  -0.565  -0.469  -0.442  -0.379  -0.709  -0.681  -0.627
141   I        -0.469  -0.404  -0.448  -0.562  -0.447  -0.536  -0.514  -0.415  -0.472
142   D        -0.469  -0.342  -0.452  -0.587  -0.352  -0.568  -0.514  -0.331  -0.478
143   R        -1.339  -1.318  -1.298  -1.301  -1.314  -1.232  -1.100  -1.062  -1.026
144   N         0.729   0.759   0.670   0.877   0.905   0.781   0.659   0.705   0.542
145   E        -1.339  -1.318  -1.298  -1.240  -1.230  -1.169  -1.100  -1.062  -1.026
146   D         0.729   0.843   0.699   0.634   0.816   0.587   0.659   0.847   0.593
147   S        -1.339  -1.318  -1.298  -1.404  -1.357  -1.337  -1.100  -1.062  -1.026
148   E         0.729   0.759   0.670   0.702   0.762   0.595   0.659   0.705   0.542
149   A        -0.469  -0.484  -0.488  -0.526  -0.556  -0.536  -0.514  -0.529  -0.525
150   V         0.401   0.443   0.479   0.048   0.075   0.143   0.073   0.141   0.194
151   M        -1.339  -1.318  -1.298  -1.057  -1.018  -0.982  -1.100  -1.062  -1.026
152   E         0.729   0.626   0.629   0.684   0.507   0.494   0.659   0.474   0.468
153   L         2.141   2.195   2.233   1.853   1.924   2.000   2.419   2.501   2.569
154   R         2.141   2.195   2.233   2.348   2.451   2.508   2.419   2.501   2.569
155   K         0.729   0.759   0.670   0.691   0.747   0.603   0.659   0.705   0.542
156   R         2.141   2.195   2.233   2.348   2.451   2.508   2.419   2.501   2.569
157   L         2.141   2.195   2.233   1.853   1.924   2.000   2.419   2.501   2.569
158   L         0.729   0.759   0.670   0.557   0.596   0.494   0.659   0.705   0.542
159   G         0.729   0.626   0.629   0.849   0.667   0.656   0.659   0.474   0.468
160   K        -0.469  -0.485  -0.484  -0.410  -0.421  -0.413  -0.514  -0.531  -0.521
161   G        -0.469  -0.404  -0.448  -0.396  -0.256  -0.367  -0.514  -0.415  -0.472
162   Q        -1.339  -1.318  -1.298  -1.188  -1.118  -1.115  -1.100  -1.062  -1.026
163   N        -0.469  -0.484  -0.488  -0.367  -0.363  -0.363  -0.514  -0.529  -0.525
164   K        -0.469  -0.533  -0.513  -0.587  -0.684  -0.664  -0.514  -0.591  -0.559
165   G        -0.469  -0.484  -0.488  -0.390  -0.440  -0.429  -0.514  -0.529  -0.525
166   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
167   G        -0.617  -0.591  -0.565  -0.692  -0.639  -0.608  -0.709  -0.665  -0.627
168   Y        -0.469  -0.342  -0.452  -0.475  -0.275  -0.438  -0.514  -0.331  -0.478
169   E        -0.469  -0.342  -0.452  -0.439  -0.211  -0.419  -0.514  -0.331  -0.478
170   T        -0.469  -0.404  -0.448  -0.341  -0.226  -0.304  -0.514  -0.415  -0.472
171   T        -0.469  -0.484  -0.488  -0.248  -0.277  -0.271  -0.514  -0.529  -0.525
172   K        -1.339  -1.318  -1.298  -1.248  -1.191  -1.177  -1.100  -1.062  -1.026
173   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
174   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
175   S         2.141   2.195   2.233   1.988   2.065   2.138   2.419   2.501   2.569
176   V        -0.469  -0.533  -0.513  -0.301  -0.411  -0.370  -0.514  -0.591  -0.559
177   D         0.729   0.843   0.699   0.634   0.816   0.587   0.659   0.847   0.593
178   R        -0.469  -0.342  -0.452  -0.428  -0.236  -0.389  -0.514  -0.331  -0.478
179   Q         0.729   0.626   0.629   0.862   0.725   0.708   0.659   0.474   0.468
180   I        -0.469  -0.533  -0.513  -0.298  -0.401  -0.336  -0.514  -0.591  -0.559
181   E        -0.469  -0.484  -0.488  -0.370  -0.378  -0.398  -0.514  -0.529  -0.525
182   D        -1.339  -1.318  -1.298  -1.199  -1.148  -1.127  -1.100  -1.062  -1.026
183   Q         0.401   0.431   0.471   0.499   0.579   0.627   0.073   0.118   0.177
184   D         0.401   0.431   0.471   0.084   0.143   0.196   0.073   0.118   0.177
185   T        -0.469  -0.484  -0.488  -0.611  -0.667  -0.645  -0.514  -0.529  -0.525
186   L        -0.469  -0.485  -0.484  -0.614  -0.663  -0.611  -0.514  -0.531  -0.521
187   Q         2.141   2.195   2.233   2.235   2.343   2.392   2.419   2.501   2.569
188   Q        -0.469  -0.533  -0.513  -0.463  -0.558  -0.556  -0.514  -0.591  -0.559
189   D        -0.469  -0.404  -0.448  -0.535  -0.438  -0.498  -0.514  -0.415  -0.472
190   L         0.729   0.626   0.629   0.452   0.273   0.290   0.659   0.474   0.468
191   I        -1.339  -1.318  -1.298  -1.305  -1.321  -1.236  -1.100  -1.062  -1.026
192   Q        -0.469  -0.484  -0.488  -0.538  -0.577  -0.578  -0.514  -0.529  -0.525
193   D         0.729   0.626   0.629   0.634   0.472   0.467   0.659   0.474   0.468
194   M         0.729   0.626   0.629   0.950   0.751   0.738   0.659   0.474   0.468
195   S         0.729   0.626   0.629   0.623   0.461   0.475   0.659   0.474   0.468
196   K        -0.469  -0.533  -0.513  -0.460  -0.530  -0.510  -0.514  -0.591  -0.559
197   L         0.729   0.626   0.629   0.515   0.363   0.379   0.659   0.474   0.468
198   V         0.729   0.626   0.629   0.907   0.756   0.752   0.659   0.474   0.468
199   G        -0.469  -0.533  -0.513  -0.372  -0.472  -0.466  -0.514  -0.591  -0.559
200   S         0.729   0.759   0.670   0.637   0.681   0.557   0.659   0.705   0.542
201   L         2.141   2.195   2.233   1.853   1.924   2.000   2.419   2.501   2.569
202   K         0.729   0.759   0.670   0.728   0.783   0.652   0.659   0.705   0.542
203   Q         2.141   2.195   2.233   2.235   2.343   2.392   2.419   2.501   2.569
204   G         0.729   0.626   0.629   0.849   0.667   0.656   0.659   0.474   0.468
205   A         2.141   2.195   2.233   2.275   2.374   2.433   2.419   2.501   2.569
206   V         0.729   0.759   0.670   0.866   0.925   0.769   0.659   0.705   0.542
207   A         0.729   0.626   0.629   0.901   0.749   0.746   0.659   0.474   0.468
208   F         0.729   0.626   0.629   0.834   0.637   0.623   0.659   0.474   0.468
209   Q         0.729   0.626   0.629   0.770   0.600   0.579   0.659   0.474   0.468
210   S         0.401   0.431   0.472   0.150   0.163   0.250   0.073   0.118   0.179
211   A         0.729   0.626   0.629   0.836   0.667   0.655   0.659   0.474   0.468
212   L         0.729   0.759   0.670   0.452   0.483   0.358   0.659   0.705   0.542
213   D        -0.469  -0.484  -0.488  -0.683  -0.740  -0.748  -0.514  -0.529  -0.525
214   E        -0.469  -0.533  -0.513  -0.384  -0.485  -0.437  -0.514  -0.591  -0.559
215   D         2.141   2.195   2.233   2.043   2.130   2.196   2.419   2.501   2.569
216   K        -1.339  -1.318  -1.298  -1.337  -1.290  -1.268  -1.100  -1.062  -1.026
217   Q        -1.339  -1.318  -1.298  -1.248  -1.207  -1.177  -1.100  -1.062  -1.026
218   V         0.729   0.626   0.629   0.870   0.700   0.701   0.659   0.474   0.468
219   L         2.141   2.195   2.233   1.853   1.924   2.000   2.419   2.501   2.569
220   G        -0.469  -0.533  -0.513  -0.332  -0.442  -0.417  -0.514  -0.591  -0.559
221   A         0.729   0.626   0.629   0.836   0.667   0.655   0.659   0.474   0.468
222   A         0.729   0.626   0.629   0.901   0.749   0.746   0.659   0.474   0.468
223   E         0.729   0.626   0.629   0.790   0.650   0.644   0.659   0.474   0.468
224   I         0.729   0.626   0.629   0.715   0.526   0.532   0.659   0.474   0.468
225   G         0.729   0.626   0.629   0.943   0.783   0.789   0.659   0.474   0.468
226   I         0.401   0.443   0.479  -0.047  -0.020   0.055   0.073   0.141   0.194
227   Q        -0.469  -0.533  -0.513  -0.138  -0.187  -0.161  -0.514  -0.591  -0.559
228   V         0.729   0.626   0.629   0.842   0.668   0.661   0.659   0.474   0.468
229   A        -0.469  -0.533  -0.513  -0.281  -0.383  -0.344  -0.514  -0.591  -0.559
230   S         0.729   0.626   0.629   0.580   0.411   0.414   0.659   0.474   0.468
231   Q        -1.339  -1.318  -1.298  -1.144  -1.093  -1.070  -1.100  -1.062  -1.026
232   G        -0.469  -0.533  -0.513  -0.553  -0.717  -0.689  -0.514  -0.591  -0.559
233   L        -0.469  -0.485  -0.484  -0.614  -0.613  -0.611  -0.514  -0.531  -0.521
234   M        -1.339  -1.318  -1.298  -1.210  -1.208  -1.138  -1.100  -1.062  -1.026
235   D         0.401   0.443   0.479  -0.036   0.023   0.084   0.073   0.141   0.194
236   V        -0.469  -0.404  -0.448  -0.508  -0.396  -0.486  -0.514  -0.415  -0.472
237   S         0.401   0.443   0.479   0.170   0.269   0.322   0.073   0.141   0.194
238   G        -0.469  -0.533  -0.513  -0.367  -0.481  -0.459  -0.514  -0.591  -0.559
239   K        -0.469  -0.533  -0.513  -0.422  -0.511  -0.464  -0.514  -0.591  -0.559
240   L         2.141   2.195   2.233   1.853   1.924   2.000   2.419   2.501   2.569
241   R        -0.469  -0.484  -0.488  -0.422  -0.449  -0.431  -0.514  -0.529  -0.525
242   K        -0.469  -0.485  -0.484  -0.454  -0.487  -0.464  -0.514  -0.531  -0.521
243   Y         2.141   2.195   2.233   2.335   2.435   2.495   2.419   2.501   2.569
244   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
245   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
246   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
247   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
248   D        -0.469  -0.533  -0.513  -0.496  -0.610  -0.546  -0.514  -0.591  -0.559
249   K        -0.469  -0.533  -0.513  -0.437  -0.523  -0.482  -0.514  -0.591  -0.559
250   S        -1.339  -1.318  -1.298  -1.255  -1.182  -1.185  -1.100  -1.062  -1.026
251   K         2.141   2.195   2.233   2.071   2.157   2.224   2.419   2.501   2.569
252   L         0.401   0.443   0.479  -0.047   0.032   0.100   0.073   0.141   0.194
253   S         0.401   0.431   0.472   0.170   0.203   0.270   0.073   0.118   0.179
254   Y         0.401   0.443   0.479   0.438   0.522   0.572   0.073   0.141   0.194
255   L         0.729   0.626   0.629   0.603   0.474   0.502   0.659   0.474   0.468
256   F         0.729   0.759   0.670   1.023   1.086   0.955   0.659   0.705   0.542
257   Y        -0.469  -0.533  -0.513  -0.499  -0.655  -0.627  -0.514  -0.591  -0.559
258   I         0.401   0.443   0.479  -0.047  -0.020   0.055   0.073   0.141   0.194
259   T        -1.339  -1.318  -1.298  -1.372  -1.335  -1.304  -1.100  -1.062  -1.026
260   V        -1.339  -1.318  -1.298  -1.340  -1.330  -1.272  -1.100  -1.062  -1.026
261   F         0.401   0.443   0.479   0.094   0.118   0.186   0.073   0.141   0.194
262   I        -0.469  -0.402  -0.452  -0.838  -0.754  -0.817  -0.514  -0.413  -0.477
263   F         0.729   0.626   0.629   0.964   0.814   0.808   0.659   0.474   0.468
264   M        -0.469  -0.533  -0.513  -0.295  -0.444  -0.409  -0.514  -0.591  -0.559
265   I         0.401   0.431   0.471   0.313   0.368   0.434   0.073   0.118   0.177
266   L        -0.469  -0.484  -0.488  -0.562  -0.577  -0.609  -0.514  -0.529  -0.525
267   G         0.729   0.626   0.629   0.808   0.611   0.598   0.659   0.474   0.468
268   L         0.729   0.626   0.629   0.515   0.363   0.379   0.659   0.474   0.468
269   V        -1.339  -1.318  -1.298  -1.068  -1.035  -0.992  -1.100  -1.062  -1.026
270   F        -0.469  -0.484  -0.488  -0.253  -0.269  -0.272  -0.514  -0.529  -0.525
271   T         0.729   0.626   0.629   0.960   0.819   0.830   0.659   0.474   0.468
272   F        -0.469  -0.533  -0.513  -0.203  -0.292  -0.266  -0.514  -0.591  -0.559
273   I        -0.469  -0.533  -0.513  -0.562  -0.673  -0.658  -0.514  -0.591  -0.559
274   I        -0.469  -0.533  -0.513  -0.562  -0.719  -0.658  -0.514  -0.591  -0.559
275   I         2.141   2.195   2.233   2.160   2.238   2.316   2.419   2.501   2.569
276   Q         0.729   0.845   0.688   0.691   0.874   0.632   0.659   0.851   0.574
277   L        -0.469  -0.402  -0.452  -0.562  -0.444  -0.543  -0.514  -0.413  -0.477
278   F         2.141   2.195   2.233   2.342   2.438   2.501   2.419   2.501   2.569
279   P         2.141   2.195   2.233   2.499   2.589   2.662   2.419   2.501   2.569
280   A        -0.469  -0.533  -0.513  -0.472  -0.593  -0.578  -0.514  -0.591  -0.559
281   L         0.401   0.431   0.471   0.185   0.255   0.317   0.073   0.118   0.177
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P53146
Output conservation file - output/P53146
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
