1     M         1.658   1.690   1.768   1.794   1.839   1.969   1.822   1.868   1.997
2     I        -0.231  -0.309  -0.216  -0.355  -0.468  -0.339  -0.452  -0.542  -0.420
3     L        -0.825  -0.829  -0.756  -1.006  -0.992  -0.897  -0.865  -0.858  -0.751
4     V        -1.257  -1.265  -1.198  -1.187  -1.252  -1.120  -1.072  -1.069  -0.968
5     Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     I        -0.830  -0.836  -0.776  -0.975  -1.004  -0.915  -0.857  -0.856  -0.769
9     R        -0.825  -0.730  -0.750  -0.980  -0.849  -0.858  -0.865  -0.759  -0.746
10    S        -1.257  -1.177  -1.183  -1.171  -1.050  -1.086  -1.072  -0.981  -0.954
11    -        -0.284  -0.195  -0.198  -0.236  -0.096  -0.107  -0.503  -0.372  -0.386
12    -        -0.931  -0.902  -0.805  -0.906  -0.868  -0.717  -0.968  -0.926  -0.799
13    I        -1.257  -1.255  -1.197  -1.155  -1.136  -1.065  -1.072  -1.060  -0.967
14    I        -0.663  -0.643  -0.696  -0.660  -0.667  -0.734  -0.658  -0.639  -0.679
15    S        -1.688  -1.640  -1.557  -1.397  -1.305  -1.205  -1.278  -1.224  -1.110
16    S        -0.825  -0.791  -0.756  -0.841  -0.794  -0.709  -0.865  -0.817  -0.751
17    S        -1.257  -1.269  -1.193  -1.227  -1.269  -1.117  -1.072  -1.072  -0.964
18    L        -0.312  -0.312  -0.232  -0.524  -0.520  -0.401  -0.559  -0.547  -0.439
19    G        -1.348  -1.303  -1.219  -1.309  -1.242  -1.118  -1.154  -1.099  -0.986
20    R         0.469   0.496   0.505   0.213   0.253   0.221   0.168   0.207   0.179
21    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
22    I        -0.663  -0.503  -0.666  -0.630  -0.371  -0.654  -0.658  -0.455  -0.643
23    H        -1.257  -1.101  -1.160  -1.082  -0.839  -0.940  -1.072  -0.902  -0.933
24    V        -0.663  -0.600  -0.710  -0.589  -0.492  -0.702  -0.658  -0.577  -0.695
25    R         1.658   1.690   1.768   1.613   1.657   1.789   1.822   1.868   1.997
26    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
27    Y        -0.727  -0.723  -0.731  -0.588  -0.641  -0.605  -0.760  -0.756  -0.727
28    N        -0.867  -0.857  -0.772  -1.070  -1.059  -0.920  -0.911  -0.884  -0.769
29    S        -0.497  -0.601  -0.668  -0.468  -0.616  -0.727  -0.456  -0.581  -0.645
30    N        -1.237  -1.265  -1.178  -1.242  -1.273  -1.145  -1.063  -1.070  -0.952
31    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
32    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
33    S        -0.727  -0.799  -0.737  -0.803  -0.890  -0.781  -0.760  -0.824  -0.732
34    Q        -1.237  -1.303  -1.182  -1.243  -1.353  -1.176  -1.063  -1.100  -0.956
35    N        -1.237  -1.239  -1.180  -1.293  -1.296  -1.217  -1.063  -1.047  -0.954
36    R         0.171   0.065  -0.077   0.202   0.043  -0.215   0.152   0.004  -0.210
37    W         0.892   0.835   0.699   1.257   1.193   1.000   0.911   0.813   0.552
38    L        -0.497  -0.680  -0.688  -0.482  -0.744  -0.764  -0.456  -0.671  -0.668
39    N        -0.867  -0.883  -0.772  -0.912  -0.917  -0.754  -0.911  -0.908  -0.768
40    R         0.171   0.065  -0.077   0.202   0.044  -0.215   0.152   0.004  -0.210
41    Q         0.171   0.065  -0.077   0.415   0.270   0.031   0.152   0.004  -0.210
42    L        -0.727  -0.740  -0.725  -0.939  -0.948  -0.923  -0.760  -0.775  -0.720
43    K        -0.127  -0.066  -0.170  -0.266  -0.178  -0.302  -0.304  -0.224  -0.356
44    D         1.658   1.690   1.768   1.620   1.668   1.796   1.822   1.868   1.997
45    P        -1.606  -1.553  -1.514  -1.358  -1.309  -1.225  -1.215  -1.160  -1.078
46    Y        -0.127  -0.061  -0.145   0.077   0.161   0.054  -0.304  -0.232  -0.321
47    T        -0.497  -0.680  -0.688  -0.265  -0.557  -0.606  -0.456  -0.671  -0.668
48    K        -0.497  -0.601  -0.668  -0.507  -0.659  -0.765  -0.456  -0.581  -0.645
49    E        -0.727  -0.749  -0.733  -0.723  -0.780  -0.742  -0.760  -0.783  -0.728
50    A        -0.218  -0.245  -0.189  -0.467  -0.503  -0.407  -0.456  -0.474  -0.389
51    K         0.892   0.835   0.699   0.804   0.735   0.528   0.911   0.813   0.552
52    V        -1.606  -1.604  -1.528  -1.505  -1.497  -1.371  -1.215  -1.200  -1.089
53    Q        -0.218  -0.227  -0.189  -0.312  -0.326  -0.271  -0.456  -0.444  -0.387
54    N        -0.497  -0.572  -0.662  -0.289  -0.412  -0.550  -0.456  -0.550  -0.638
55    L         0.541   0.652   0.582   0.434   0.629   0.467   0.303   0.497   0.331
56    R         0.892   0.835   0.699   0.901   0.824   0.601   0.911   0.813   0.552
57    S         1.658   1.690   1.768   1.529   1.574   1.706   1.822   1.868   1.997
58    R         1.658   1.690   1.768   1.611   1.657   1.787   1.822   1.868   1.997
59    A         1.658   1.690   1.768   1.626   1.667   1.802   1.822   1.868   1.997
60    A         0.892   0.971   0.725   0.955   1.053   0.735   0.911   1.032   0.599
61    F         0.541   0.475   0.536   0.553   0.446   0.535   0.303   0.167   0.241
62    K         1.658   1.690   1.768   1.494   1.546   1.671   1.822   1.868   1.997
63    L         1.658   1.690   1.768   1.507   1.558   1.683   1.822   1.868   1.997
64    M        -0.867  -0.800  -0.767  -0.813  -0.711  -0.661  -0.911  -0.831  -0.763
65    Q        -0.127   0.038  -0.135  -0.057   0.192  -0.067  -0.304  -0.066  -0.301
66    I         0.382   0.391   0.484   0.040   0.038   0.180  -0.000   0.002   0.137
67    D         0.892   0.858   0.723   0.944   0.909   0.719   0.911   0.852   0.596
68    D         0.382   0.391   0.483   0.046   0.034   0.180  -0.000   0.002   0.134
69    K         0.171   0.118  -0.049   0.177   0.114  -0.112   0.152   0.071  -0.169
70    Y         0.892   0.783   0.715   1.147   1.008   0.900   0.911   0.727   0.581
71    R         0.892   0.971   0.725   0.960   1.062   0.760   0.911   1.032   0.599
72    L        -0.727  -0.722  -0.727  -0.825  -0.813  -0.803  -0.760  -0.742  -0.722
73    F         0.892   0.858   0.723   1.012   0.975   0.773   0.911   0.852   0.596
74    S        -1.237  -1.183  -1.166  -1.197  -1.111  -1.072  -1.063  -1.004  -0.942
75    K        -0.497  -0.449  -0.621  -0.447  -0.378  -0.605  -0.456  -0.401  -0.589
76    N        -1.606  -1.627  -1.539  -1.491  -1.509  -1.415  -1.215  -1.216  -1.097
77    R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
78    T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
79    D        -0.931  -0.902  -0.805  -1.015  -0.955  -0.825  -0.968  -0.925  -0.799
80    Q        -0.727  -0.817  -0.739  -0.686  -0.816  -0.718  -0.760  -0.841  -0.734
81    R        -1.237  -1.244  -1.174  -1.187  -1.162  -1.085  -1.063  -1.054  -0.949
82    I         0.382   0.393   0.486   0.148   0.158   0.306  -0.000   0.007   0.142
83    L        -0.218  -0.216  -0.185  -0.437  -0.399  -0.352  -0.456  -0.433  -0.381
84    D         1.658   1.690   1.768   1.620   1.668   1.796   1.822   1.868   1.997
85    L         0.892   0.858   0.723   0.829   0.793   0.604   0.911   0.852   0.596
86    G         1.658   1.690   1.768   1.724   1.766   1.900   1.822   1.868   1.997
87    Y         0.541   0.652   0.582   0.553   0.726   0.612   0.303   0.497   0.331
88    A         1.658   1.690   1.768   1.626   1.667   1.802   1.822   1.868   1.997
89    P         1.658   1.690   1.768   1.785   1.829   1.960   1.822   1.868   1.997
90    G         1.658   1.690   1.768   1.724   1.766   1.900   1.822   1.868   1.997
91    A         0.892   0.858   0.723   0.922   0.873   0.670   0.911   0.852   0.596
92    W         1.658   1.690   1.768   1.915   1.964   2.089   1.822   1.868   1.997
93    S         0.541   0.559   0.529   0.372   0.399   0.348   0.303   0.327   0.226
94    Q         1.658   1.690   1.768   1.773   1.823   1.948   1.822   1.868   1.997
95    V         0.892   0.835   0.699   1.006   0.931   0.739   0.911   0.813   0.552
96    A         1.658   1.690   1.768   1.626   1.667   1.802   1.822   1.868   1.997
97    R        -1.097  -1.187  -1.158  -1.043  -1.204  -1.169  -0.911  -0.994  -0.931
98    Q        -0.727  -0.718  -0.716  -0.719  -0.690  -0.655  -0.760  -0.745  -0.710
99    R         0.892   0.858   0.723   0.903   0.860   0.648   0.911   0.852   0.596
100   S        -1.237  -1.150  -1.172  -1.186  -1.065  -1.112  -1.063  -0.972  -0.948
101   S        -1.606  -1.570  -1.522  -1.423  -1.369  -1.312  -1.215  -1.173  -1.084
102   P        -0.727  -0.751  -0.724  -0.654  -0.653  -0.646  -0.760  -0.761  -0.717
103   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
104   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
105   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
106   N        -1.237  -1.241  -1.173  -1.212  -1.229  -1.140  -1.063  -1.048  -0.948
107   S        -0.727  -0.665  -0.718  -0.692  -0.568  -0.656  -0.760  -0.671  -0.709
108   M        -1.237  -1.257  -1.175  -1.134  -1.181  -1.065  -1.063  -1.063  -0.949
109   I         0.382   0.391   0.484   0.148   0.154   0.301  -0.000   0.002   0.137
110   L        -0.218  -0.134  -0.187  -0.434  -0.321  -0.349  -0.456  -0.357  -0.386
111   G         1.658   1.690   1.768   1.724   1.766   1.900   1.822   1.868   1.997
112   V         0.541   0.497   0.517   0.462   0.371   0.377   0.303   0.210   0.203
113   D         1.658   1.690   1.768   1.620   1.668   1.796   1.822   1.868   1.997
114   I         0.541   0.660   0.572   0.366   0.575   0.380   0.303   0.511   0.310
115   L        -0.497  -0.526  -0.663  -0.452  -0.481  -0.679  -0.456  -0.489  -0.639
116   P        -1.097  -1.061  -1.131  -0.812  -0.764  -0.890  -0.911  -0.867  -0.906
117   C         0.171   0.065  -0.077   0.519   0.371   0.120   0.152   0.004  -0.210
118   E        -1.606  -1.562  -1.519  -1.418  -1.356  -1.309  -1.215  -1.166  -1.082
119   P         1.658   1.690   1.768   1.785   1.829   1.960   1.822   1.868   1.997
120   P         0.892   0.835   0.699   1.105   1.030   0.831   0.911   0.813   0.552
121   H        -1.237  -1.200  -1.165  -1.116  -1.068  -0.983  -1.063  -1.020  -0.942
122   G         1.658   1.690   1.768   1.724   1.766   1.900   1.822   1.868   1.997
123   V         0.171   0.189  -0.064   0.369   0.398   0.049   0.152   0.174  -0.191
124   N        -1.097  -1.044  -1.127  -0.977  -0.910  -0.999  -0.911  -0.851  -0.902
125   S        -0.497  -0.526  -0.663  -0.379  -0.412  -0.580  -0.456  -0.489  -0.639
126   I        -0.127  -0.049  -0.170  -0.161  -0.050  -0.232  -0.304  -0.210  -0.358
127   Q         0.892   0.858   0.723   1.117   1.086   0.904   0.911   0.852   0.596
128   A         0.382   0.464   0.509   0.193   0.339   0.395  -0.000   0.147   0.188
129   N         0.541   0.497   0.517   0.476   0.394   0.387   0.303   0.210   0.203
130   I         0.892   0.783   0.715   0.954   0.817   0.715   0.911   0.727   0.581
131   L         0.171   0.065  -0.077   0.175   0.040  -0.168   0.152   0.004  -0.210
132   A        -0.497  -0.506  -0.648  -0.470  -0.487  -0.699  -0.456  -0.467  -0.622
133   K         0.892   0.858   0.723   0.834   0.802   0.627   0.911   0.852   0.596
134   R        -1.606  -1.614  -1.538  -1.507  -1.511  -1.408  -1.215  -1.207  -1.096
135   T         1.658   1.690   1.768   1.770   1.822   1.945   1.822   1.868   1.997
136   H         0.171   0.021  -0.062   0.484   0.274   0.118   0.152  -0.061  -0.189
137   D        -1.606  -1.540  -1.525  -1.326  -1.227  -1.207  -1.215  -1.147  -1.087
138   L        -0.727  -0.755  -0.736  -0.911  -0.954  -0.901  -0.760  -0.788  -0.731
139   I         0.541   0.475   0.536   0.366   0.230   0.304   0.303   0.167   0.241
140   R        -0.127  -0.176  -0.169  -0.272  -0.354  -0.347  -0.304  -0.369  -0.354
141   L        -1.237  -1.265  -1.178  -1.191  -1.209  -1.076  -1.063  -1.070  -0.952
142   F        -0.497  -0.556  -0.648  -0.244  -0.349  -0.459  -0.456  -0.529  -0.622
143   F         0.541   0.475   0.536   0.434   0.293   0.367   0.303   0.167   0.241
144   S        -0.830  -0.767  -0.757  -0.834  -0.738  -0.728  -0.857  -0.776  -0.748
145   K        -0.830  -0.802  -0.752  -0.938  -0.893  -0.820  -0.857  -0.820  -0.742
146   H        -0.312  -0.339  -0.231  -0.333  -0.391  -0.227  -0.559  -0.581  -0.438
147   F        -0.284  -0.269  -0.234  -0.365  -0.358  -0.304  -0.503  -0.487  -0.437
148   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
149   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
150   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
151   R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
152   H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
153   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
154   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
155   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
156   H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
157   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
158   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
159   H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
160   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
161   Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
162   F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
163   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
164   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
165   M        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
166   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
167   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
168   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
169   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
170   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
171   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
172   H        -0.284  -0.327  -0.244  -0.225  -0.303  -0.193  -0.503  -0.563  -0.451
173   V         0.608   0.684   0.616   0.412   0.539   0.417   0.427   0.555   0.396
174   K        -0.284  -0.327  -0.244  -0.543  -0.620  -0.498  -0.503  -0.563  -0.451
175   D        -0.284  -0.280  -0.217  -0.350  -0.340  -0.261  -0.503  -0.498  -0.413
176   T         0.608   0.552   0.587   0.654   0.560   0.598   0.427   0.314   0.340
177   E        -0.284  -0.327  -0.244  -0.354  -0.437  -0.314  -0.503  -0.563  -0.451
178   L        -0.284  -0.252  -0.218  -0.456  -0.396  -0.384  -0.503  -0.457  -0.415
179   Y         0.608   0.552   0.587   0.636   0.533   0.552   0.427   0.314   0.340
180   R        -0.931  -0.895  -0.805  -1.050  -0.974  -0.860  -0.968  -0.919  -0.799
181   E        -0.284  -0.327  -0.244  -0.364  -0.452  -0.326  -0.503  -0.563  -0.451
182   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
183   F         0.608   0.555   0.556   0.629   0.540   0.522   0.427   0.320   0.280
184   T        -0.284  -0.230  -0.217  -0.395  -0.318  -0.287  -0.503  -0.423  -0.413
185   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
186   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
187   D        -0.284  -0.296  -0.244  -0.498  -0.526  -0.463  -0.503  -0.521  -0.451
188   I        -0.284  -0.296  -0.244  -0.450  -0.497  -0.420  -0.503  -0.521  -0.451
189   Y        -0.931  -0.900  -0.805  -1.096  -1.071  -0.906  -0.968  -0.924  -0.799
190   E        -0.284  -0.291  -0.242  -0.241  -0.244  -0.182  -0.503  -0.513  -0.449
191   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
192   P        -0.284  -0.258  -0.214  -0.292  -0.262  -0.193  -0.503  -0.466  -0.410
193   N         0.723   0.784   0.633   0.750   0.849   0.589   0.631   0.728   0.427
194   T        -0.830  -0.805  -0.754  -0.818  -0.783  -0.728  -0.857  -0.821  -0.745
195   N         1.658   1.690   1.768   1.675   1.733   1.851   1.822   1.868   1.997
196   S        -0.312  -0.260  -0.225  -0.630  -0.546  -0.498  -0.559  -0.490  -0.431
197   T        -0.284  -0.194  -0.225  -0.418  -0.255  -0.345  -0.503  -0.371  -0.425
198   L        -0.931  -0.896  -0.805  -0.980  -0.907  -0.790  -0.968  -0.919  -0.799
199   I        -0.931  -0.896  -0.805  -1.020  -0.954  -0.830  -0.968  -0.919  -0.799
200   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
201   E        -1.237  -1.191  -1.168  -1.146  -1.101  -1.032  -1.063  -1.008  -0.944
202   R        -1.606  -1.570  -1.522  -1.341  -1.301  -1.207  -1.215  -1.173  -1.084
203   E        -0.127  -0.131  -0.168  -0.089  -0.137  -0.152  -0.304  -0.333  -0.354
204   K        -1.606  -1.557  -1.518  -1.353  -1.265  -1.230  -1.215  -1.163  -1.081
205   F        -0.867  -0.862  -0.772  -0.921  -0.900  -0.778  -0.911  -0.889  -0.769
206   P         0.171   0.065  -0.077   0.458   0.314   0.099   0.152   0.004  -0.210
207   V         0.892   0.835   0.699   0.974   0.893   0.674   0.911   0.813   0.552
208   D         0.892   0.971   0.725   0.944   1.053   0.721   0.911   1.032   0.599
209   V        -0.867  -0.856  -0.772  -1.043  -1.026  -0.899  -0.911  -0.883  -0.768
210   I         0.382   0.393   0.486   0.148   0.158   0.306  -0.000   0.007   0.142
211   I        -0.218  -0.243  -0.188  -0.434  -0.450  -0.352  -0.456  -0.472  -0.388
212   S         1.658   1.690   1.768   1.529   1.574   1.706   1.822   1.868   1.997
213   D         1.658   1.690   1.768   1.620   1.668   1.796   1.822   1.868   1.997
214   M         1.658   1.690   1.768   1.794   1.839   1.969   1.822   1.868   1.997
215   Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
216   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
217   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
218   W        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
219   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
220   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
221   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
222   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
223   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
224   F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
225   W        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
226   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
227   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
228   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
229   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
230   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
231   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
232   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
233   Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
234   F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
235   R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
236   M         0.892   0.858   0.723   1.086   1.041   0.825   0.911   0.852   0.596
237   A        -0.497  -0.548  -0.666  -0.347  -0.419  -0.600  -0.456  -0.514  -0.644
238   N         0.171   0.065  -0.077   0.309   0.163  -0.098   0.152   0.004  -0.210
239   T        -0.497  -0.680  -0.688  -0.178  -0.441  -0.463  -0.456  -0.671  -0.668
240   S         0.382   0.399   0.482   0.122   0.150   0.289  -0.000   0.018   0.133
241   G         1.658   1.690   1.768   1.724   1.766   1.900   1.822   1.868   1.997
242   V        -0.497  -0.419  -0.646  -0.368  -0.248  -0.601  -0.456  -0.359  -0.619
243   S        -1.976  -1.927  -1.843  -1.835  -1.752  -1.640  -1.367  -1.316  -1.199
244   I        -1.237  -1.212  -1.162  -1.274  -1.238  -1.151  -1.063  -1.029  -0.939
245   R        -0.727  -0.670  -0.716  -0.851  -0.744  -0.822  -0.760  -0.678  -0.707
246   D         1.658   1.690   1.768   1.620   1.668   1.796   1.822   1.868   1.997
247   H         1.658   1.690   1.768   1.844   1.893   2.019   1.822   1.868   1.997
248   Y        -0.727  -0.749  -0.739  -0.648  -0.714  -0.705  -0.760  -0.780  -0.734
249   Q        -1.606  -1.540  -1.525  -1.387  -1.319  -1.261  -1.215  -1.147  -1.087
250   S         0.892   0.835   0.699   0.854   0.784   0.594   0.911   0.813   0.552
251   I         0.382   0.408   0.493   0.252   0.289   0.416  -0.000   0.036   0.155
252   D         0.363   0.401   0.489   0.135   0.204   0.340  -0.038   0.022   0.147
253   L         1.658   1.690   1.768   1.496   1.545   1.673   1.822   1.868   1.997
254   C         1.658   1.690   1.768   1.881   1.930   2.056   1.822   1.868   1.997
255   D         0.038  -0.105  -0.144   0.095  -0.115  -0.182  -0.038  -0.243  -0.309
256   A         0.038   0.018  -0.110   0.101   0.057  -0.143  -0.038  -0.070  -0.259
257   A         1.658   1.690   1.768   1.650   1.696   1.826   1.822   1.868   1.997
258   L         1.658   1.690   1.768   1.496   1.545   1.673   1.822   1.868   1.997
259   V        -0.663  -0.718  -0.717  -0.501  -0.567  -0.556  -0.658  -0.722  -0.703
260   T        -0.394  -0.366  -0.267  -0.596  -0.560  -0.412  -0.658  -0.616  -0.485
261   A         1.658   1.690   1.768   1.650   1.696   1.826   1.822   1.868   1.997
262   I        -1.257  -1.273  -1.198  -1.251  -1.275  -1.171  -1.072  -1.075  -0.968
263   D        -0.663  -0.734  -0.736  -0.643  -0.762  -0.776  -0.658  -0.739  -0.724
264   L         0.038  -0.105  -0.144  -0.012  -0.215  -0.272  -0.038  -0.243  -0.309
265   L         1.658   1.690   1.768   1.496   1.545   1.673   1.822   1.868   1.997
266   R        -0.663  -0.519  -0.681  -0.735  -0.524  -0.758  -0.658  -0.475  -0.660
267   P         0.038   0.018  -0.110   0.191   0.155  -0.103  -0.038  -0.070  -0.259
268   L        -1.257  -1.198  -1.179  -1.179  -1.075  -1.072  -1.072  -1.003  -0.951
269   G         0.816   0.748   0.657   0.928   0.822   0.648   0.789   0.667   0.473
270   S         0.816   0.748   0.657   0.736   0.640   0.489   0.789   0.667   0.473
271   F         0.469   0.475   0.504   0.428   0.432   0.470   0.168   0.166   0.177
272   V        -0.231  -0.123  -0.174  -0.310  -0.146  -0.208  -0.452  -0.295  -0.359
273   C         0.038   0.026  -0.122   0.332   0.300   0.051  -0.038  -0.058  -0.276
274   K         1.658   1.690   1.768   1.482   1.525   1.659   1.822   1.868   1.997
275   L        -0.825  -0.821  -0.764  -0.892  -0.861  -0.767  -0.865  -0.846  -0.758
276   Y         0.038   0.010  -0.124   0.346   0.317   0.112  -0.038  -0.079  -0.279
277   T        -0.825  -0.814  -0.756  -0.844  -0.827  -0.734  -0.865  -0.841  -0.751
278   G         1.658   1.690   1.768   1.745   1.792   1.920   1.822   1.868   1.997
279   E        -1.257  -1.204  -1.176  -1.363  -1.287  -1.245  -1.072  -1.009  -0.948
280   E         1.658   1.690   1.768   1.725   1.772   1.900   1.822   1.868   1.997
281   E        -0.663  -0.627  -0.705  -0.629  -0.594  -0.705  -0.658  -0.611  -0.688
282   N        -1.257  -1.255  -1.186  -1.323  -1.342  -1.214  -1.072  -1.059  -0.957
283   L         0.816   0.738   0.671   0.705   0.595   0.484   0.789   0.650   0.500
284   F         0.363   0.389   0.482   0.033   0.071   0.219  -0.038  -0.001   0.133
285   K        -0.231  -0.242  -0.195  -0.340  -0.321  -0.273  -0.452  -0.447  -0.388
286   K        -0.663  -0.734  -0.736  -0.693  -0.795  -0.777  -0.658  -0.739  -0.724
287   R         0.038   0.018  -0.110   0.001  -0.036  -0.284  -0.038  -0.070  -0.259
288   M         0.363   0.389   0.482   0.110   0.147   0.295  -0.038  -0.001   0.133
289   Q        -0.231  -0.235  -0.197  -0.409  -0.408  -0.341  -0.452  -0.438  -0.391
290   A        -0.663  -0.718  -0.717  -0.810  -0.919  -0.913  -0.658  -0.722  -0.703
291   V        -0.231  -0.285  -0.218  -0.160  -0.224  -0.115  -0.452  -0.515  -0.422
292   F         1.658   1.690   1.768   1.701   1.748   1.877   1.822   1.868   1.997
293   T        -1.257  -1.204  -1.176  -1.248  -1.191  -1.111  -1.072  -1.009  -0.948
294   N        -0.663  -0.633  -0.693  -0.743  -0.702  -0.786  -0.658  -0.620  -0.674
295   V         1.658   1.690   1.768   1.708   1.756   1.883   1.822   1.868   1.997
296   H        -1.688  -1.650  -1.557  -1.417  -1.364  -1.225  -1.278  -1.232  -1.110
297   K        -1.257  -1.272  -1.193  -1.264  -1.253  -1.145  -1.072  -1.074  -0.964
298   F        -0.825  -0.821  -0.764  -0.723  -0.713  -0.625  -0.865  -0.846  -0.758
299   K         1.658   1.690   1.768   1.482   1.525   1.659   1.822   1.868   1.997
300   P         1.658   1.690   1.768   1.805   1.857   1.980   1.822   1.868   1.997
301   D        -0.825  -0.818  -0.753  -1.049  -1.048  -0.938  -0.865  -0.846  -0.748
302   A         1.658   1.690   1.768   1.650   1.696   1.826   1.822   1.868   1.997
303   S         0.816   0.899   0.687   0.792   0.903   0.639   0.789   0.919   0.529
304   R        -0.497  -0.680  -0.688  -0.454  -0.750  -0.799  -0.456  -0.671  -0.668
305   D        -0.497  -0.556  -0.648  -0.435  -0.548  -0.703  -0.456  -0.529  -0.622
306   E         0.892   0.835   0.699   1.037   0.963   0.753   0.911   0.813   0.552
307   S         0.171   0.143  -0.043   0.162   0.124  -0.157   0.152   0.104  -0.161
308   K        -0.218  -0.231  -0.196  -0.525  -0.517  -0.477  -0.456  -0.451  -0.396
309   E         0.892   0.783   0.715   1.018   0.864   0.743   0.911   0.727   0.581
310   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
311   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
312   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
313   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
314   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
315   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
316   T        -1.237  -1.109  -1.166  -1.223  -1.061  -1.094  -1.063  -0.939  -0.943
317   Y         0.892   0.783   0.715   1.120   0.970   0.847   0.911   0.727   0.581
318   Y        -0.127  -0.092  -0.149  -0.020   0.053  -0.030  -0.304  -0.229  -0.323
319   I        -0.218  -0.264  -0.186  -0.350  -0.400  -0.281  -0.456  -0.491  -0.383
320   G        -0.497  -0.556  -0.648  -0.221  -0.312  -0.439  -0.456  -0.529  -0.622
321   L        -1.237  -1.212  -1.162  -1.376  -1.340  -1.263  -1.063  -1.029  -0.939
322   K        -0.867  -0.790  -0.773  -1.002  -0.871  -0.839  -0.911  -0.826  -0.770
323   K         0.171   0.021  -0.062   0.148  -0.055  -0.184   0.152  -0.061  -0.189
324   K         0.892   0.835   0.699   0.816   0.749   0.554   0.911   0.813   0.552
325   R        -1.348  -1.313  -1.219  -1.421  -1.369  -1.229  -1.154  -1.108  -0.986
326   N        -0.117  -0.162  -0.190  -0.176  -0.270  -0.347  -0.261  -0.330  -0.375
327   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
328   V        -0.312  -0.343  -0.241  -0.423  -0.460  -0.309  -0.559  -0.587  -0.451
329   D         0.723   0.628   0.602   0.663   0.503   0.431   0.631   0.454   0.369
330   K         0.723   0.758   0.631   0.596   0.643   0.462   0.631   0.684   0.425
331   L        -0.117  -0.181  -0.195  -0.280  -0.373  -0.416  -0.261  -0.356  -0.382
332   D        -0.830  -0.836  -0.776  -0.982  -0.998  -0.921  -0.857  -0.856  -0.769
333   V        -0.117  -0.181  -0.195  -0.081  -0.181  -0.248  -0.261  -0.356  -0.382
334   F         1.658   1.690   1.768   1.707   1.756   1.883   1.822   1.868   1.997
335   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
336   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
337   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
338   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
339   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
340   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
341   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
342   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
343   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
344   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
345   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
346   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
347   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
348   S        -0.727  -0.654  -0.716  -0.672  -0.581  -0.609  -0.760  -0.689  -0.709
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P53123
Output conservation file - output/P53123
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
