1     M        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
2     E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
19    R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
20    R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
21    M        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
22    G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
23    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
24    R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
25    G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
26    W        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
27    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
28    A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
29    C        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
30    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
31    R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
32    P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
33    H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
34    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
35    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
36    G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
37    R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
38    I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
39    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
40    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
41    F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
42    M         1.609   1.609   1.609   1.902   1.917   1.902   1.609   1.609   1.609
43    S        -0.619  -0.619  -0.619  -0.897  -0.948  -0.897  -0.619  -0.619  -0.619
44    I         1.609   1.609   1.609   1.514   1.514   1.514   1.609   1.609   1.609
45    L        -0.619  -0.619  -0.619  -1.139  -1.130  -1.139  -0.619  -0.619  -0.619
46    F        -0.619  -0.619  -0.619  -0.786  -0.762  -0.786  -0.619  -0.619  -0.619
47    I         1.609   1.609   1.609   1.514   1.514   1.514   1.609   1.609   1.609
48    T        -0.619  -0.619  -0.619  -0.338  -0.343  -0.338  -0.619  -0.619  -0.619
49    S        -0.619  -0.619  -0.619  -0.897  -0.948  -0.897  -0.619  -0.619  -0.619
50    A        -0.619  -0.619  -0.619  -0.736  -0.688  -0.736  -0.619  -0.619  -0.619
51    E        -0.619  -0.619  -0.619  -0.816  -0.784  -0.816  -0.619  -0.619  -0.619
52    L         1.609   1.609   1.609   1.215   1.251   1.215   1.609   1.609   1.609
53    S        -0.619  -0.619  -0.619  -0.908  -0.926  -0.908  -0.619  -0.619  -0.619
54    S        -0.619  -0.619  -0.619  -0.562  -0.574  -0.562  -0.619  -0.619  -0.619
55    D        -0.619  -0.619  -0.619  -0.836  -0.871  -0.836  -0.619  -0.619  -0.619
56    V         1.609   1.609   1.609   1.527   1.485   1.527   1.609   1.609   1.609
57    S        -0.619  -0.619  -0.619  -0.897  -0.948  -0.897  -0.619  -0.619  -0.619
58    S         1.609   1.609   1.609   1.298   1.266   1.298   1.609   1.609   1.609
59    R        -0.619  -0.619  -0.619  -0.384  -0.343  -0.384  -0.619  -0.619  -0.619
60    E        -0.619  -0.619  -0.619  -0.458  -0.452  -0.458  -0.619  -0.619  -0.619
61    V        -0.619  -0.619  -0.619  -0.959  -0.959  -0.959  -0.619  -0.619  -0.619
62    Y        -0.619  -0.619  -0.619  -0.402  -0.402  -0.402  -0.619  -0.619  -0.619
63    M        -0.619  -0.619  -0.619  -0.668  -0.625  -0.668  -0.619  -0.619  -0.619
64    P         1.609   1.609   1.609   1.889   1.903   1.889   1.609   1.609   1.609
65    I         1.609   1.609   1.609   1.514   1.514   1.514   1.609   1.609   1.609
66    F        -0.619  -0.619  -0.619  -0.514  -0.533  -0.514  -0.619  -0.619  -0.619
67    N        -0.619  -0.619  -0.619  -0.412  -0.412  -0.412  -0.619  -0.619  -0.619
68    N         1.609   1.609   1.609   1.593   1.571   1.593   1.609   1.609   1.609
69    K        -0.619  -0.619  -0.619  -0.449  -0.402  -0.449  -0.619  -0.619  -0.619
70    L         1.609   1.609   1.609   1.215   1.251   1.215   1.609   1.609   1.609
71    S        -0.619  -0.619  -0.619  -0.756  -0.773  -0.756  -0.619  -0.619  -0.619
72    F         1.609   1.609   1.609   1.749   1.739   1.749   1.609   1.609   1.609
73    K        -0.619  -0.619  -0.619  -0.600  -0.605  -0.600  -0.619  -0.619  -0.619
74    V        -0.619  -0.619  -0.619  -0.959  -0.959  -0.959  -0.619  -0.619  -0.619
75    P        -0.619  -0.619  -0.619  -0.133  -0.113  -0.133  -0.619  -0.619  -0.619
76    P         1.609   1.609   1.609   1.889   1.903   1.889   1.609   1.609   1.609
77    I        -0.619  -0.619  -0.619  -0.477  -0.482  -0.477  -0.619  -0.619  -0.619
78    K         1.609   1.609   1.609   1.619   1.627   1.619   1.609   1.609   1.609
79    R        -0.619  -0.619  -0.619  -0.449  -0.402  -0.449  -0.619  -0.619  -0.619
80    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
81    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
82    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
83    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
84    G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
85    A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
86    A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
87    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
88    Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
89    E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
90    D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
91    F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
92    E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
93    Y        -0.619  -0.619  -0.619  -0.142  -0.141  -0.142  -0.619  -0.619  -0.619
94    S        -0.619  -0.619  -0.619  -0.756  -0.773  -0.756  -0.619  -0.619  -0.619
95    S        -0.619  -0.619  -0.619  -0.897  -0.948  -0.897  -0.619  -0.619  -0.619
96    N        -0.619  -0.619  -0.619  -0.619  -0.646  -0.619  -0.619  -0.619  -0.619
97    N        -0.619  -0.619  -0.619  -0.514  -0.512  -0.514  -0.619  -0.619  -0.619
98    S         1.609   1.609   1.609   1.298   1.266   1.298   1.609   1.609   1.609
99    A        -0.619  -0.619  -0.619  -0.677  -0.678  -0.677  -0.619  -0.619  -0.619
100   S        -0.619  -0.619  -0.619  -0.836  -0.871  -0.836  -0.619  -0.619  -0.619
101   D        -0.619  -0.619  -0.619  -0.458  -0.452  -0.458  -0.619  -0.619  -0.619
102   G        -0.619  -0.619  -0.619  -0.727  -0.730  -0.727  -0.619  -0.619  -0.619
103   A        -0.619  -0.619  -0.619  -0.677  -0.678  -0.677  -0.619  -0.619  -0.619
104   F        -0.619  -0.619  -0.619  -0.311  -0.323  -0.311  -0.619  -0.619  -0.619
105   C        -0.619  -0.619  -0.619  -0.204  -0.198  -0.204  -0.619  -0.619  -0.619
106   T         1.609   1.609   1.609   1.711   1.711   1.711   1.609   1.609   1.609
107   V        -0.619  -0.619  -0.619  -0.402  -0.422  -0.402  -0.619  -0.619  -0.619
108   F         1.609   1.609   1.609   1.749   1.739   1.749   1.609   1.609   1.609
109   N        -0.619  -0.619  -0.619  -0.543  -0.553  -0.543  -0.619  -0.619  -0.619
110   A        -0.619  -0.619  -0.619  -0.248  -0.217  -0.248  -0.619  -0.619  -0.619
111   G        -0.619  -0.619  -0.619  -0.514  -0.512  -0.514  -0.619  -0.619  -0.619
112   M        -0.619  -0.619  -0.619  -0.320  -0.304  -0.320  -0.619  -0.619  -0.619
113   N         1.609   1.609   1.609   1.593   1.571   1.593   1.609   1.609   1.609
114   D        -0.619  -0.619  -0.619  -0.677  -0.688  -0.677  -0.619  -0.619  -0.619
115   A        -0.619  -0.619  -0.619  -0.449  -0.422  -0.449  -0.619  -0.619  -0.619
116   S        -0.619  -0.619  -0.619  -0.677  -0.678  -0.677  -0.619  -0.619  -0.619
117   R        -0.619  -0.619  -0.619  -0.449  -0.402  -0.449  -0.619  -0.619  -0.619
118   E        -0.619  -0.619  -0.619  -0.533  -0.543  -0.533  -0.619  -0.619  -0.619
119   V        -0.619  -0.619  -0.619  -0.959  -0.959  -0.959  -0.619  -0.619  -0.619
120   V        -0.619  -0.619  -0.619  -0.514  -0.543  -0.514  -0.619  -0.619  -0.619
121   F         1.609   1.609   1.609   1.749   1.739   1.749   1.609   1.609   1.609
122   E        -0.619  -0.619  -0.619  -0.816  -0.784  -0.816  -0.619  -0.619  -0.619
123   I         1.609   1.609   1.609   1.514   1.514   1.514   1.609   1.609   1.609
124   H        -0.619  -0.619  -0.619  -0.284  -0.275  -0.284  -0.619  -0.619  -0.619
125   V        -0.619  -0.619  -0.619  -0.736  -0.762  -0.736  -0.619  -0.619  -0.619
126   M        -0.619  -0.619  -0.619  -0.320  -0.304  -0.320  -0.619  -0.619  -0.619
127   D        -0.619  -0.619  -0.619  -0.533  -0.543  -0.533  -0.619  -0.619  -0.619
128   V        -0.619  -0.619  -0.619  -0.562  -0.594  -0.562  -0.619  -0.619  -0.619
129   L        -0.619  -0.619  -0.619  -0.816  -0.784  -0.816  -0.619  -0.619  -0.619
130   Q        -0.619  -0.619  -0.619  -0.449  -0.442  -0.449  -0.619  -0.619  -0.619
131   E        -0.619  -0.619  -0.619  -0.257  -0.246  -0.257  -0.619  -0.619  -0.619
132   E        -0.619  -0.619  -0.619  -0.524  -0.512  -0.524  -0.619  -0.619  -0.619
133   T        -0.619  -0.619  -0.619  -0.590  -0.615  -0.590  -0.619  -0.619  -0.619
134   D        -0.619  -0.619  -0.619  -0.619  -0.646  -0.619  -0.619  -0.619  -0.619
135   S        -0.619  -0.619  -0.619  -0.897  -0.948  -0.897  -0.619  -0.619  -0.619
136   S        -0.619  -0.619  -0.619  -0.836  -0.871  -0.836  -0.619  -0.619  -0.619
137   R         1.609   1.609   1.609   1.813   1.863   1.813   1.609   1.609   1.609
138   F         1.609   1.609   1.609   1.749   1.739   1.749   1.609   1.609   1.609
139   G         1.609   1.609   1.609   1.749   1.767   1.749   1.609   1.609   1.609
140   G        -0.619  -0.619  -0.619  -0.302  -0.275  -0.302  -0.619  -0.619  -0.619
141   T         1.609   1.609   1.609   1.711   1.711   1.711   1.609   1.609   1.609
142   S        -0.619  -0.619  -0.619  -0.756  -0.773  -0.756  -0.619  -0.619  -0.619
143   H        -0.619  -0.619  -0.619  -0.571  -0.584  -0.571  -0.619  -0.619  -0.619
144   E        -0.619  -0.619  -0.619  -0.756  -0.773  -0.756  -0.619  -0.619  -0.619
145   R        -0.619  -0.619  -0.619  -0.449  -0.402  -0.449  -0.619  -0.619  -0.619
146   G         1.609   1.609   1.609   1.749   1.767   1.749   1.609   1.609   1.609
147   R        -0.619  -0.619  -0.619  -0.449  -0.402  -0.449  -0.619  -0.619  -0.619
148   Q         1.609   1.609   1.609   1.813   1.808   1.813   1.609   1.609   1.609
149   S        -0.619  -0.619  -0.619  -0.897  -0.948  -0.897  -0.619  -0.619  -0.619
150   L        -0.619  -0.619  -0.619  -0.959  -0.959  -0.959  -0.619  -0.619  -0.619
151   G        -0.619  -0.619  -0.619  -0.514  -0.512  -0.514  -0.619  -0.619  -0.619
152   F        -0.619  -0.619  -0.619  -0.293  -0.284  -0.293  -0.619  -0.619  -0.619
153   S        -0.619  -0.619  -0.619  -0.836  -0.871  -0.836  -0.619  -0.619  -0.619
154   V        -0.619  -0.619  -0.619  -0.736  -0.762  -0.736  -0.619  -0.619  -0.619
155   F        -0.619  -0.619  -0.619  -0.311  -0.323  -0.311  -0.619  -0.619  -0.619
156   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
157   N        -0.619  -0.619  -0.619  -0.619  -0.646  -0.619  -0.619  -0.619  -0.619
158   K        -0.619  -0.619  -0.619  -0.524  -0.512  -0.524  -0.619  -0.619  -0.619
159   N        -0.619  -0.619  -0.619  -0.619  -0.646  -0.619  -0.619  -0.619  -0.619
160   G        -0.619  -0.619  -0.619  -0.357  -0.343  -0.357  -0.619  -0.619  -0.619
161   D        -0.619  -0.619  -0.619  -0.619  -0.646  -0.619  -0.619  -0.619  -0.619
162   L         1.609   1.609   1.609   1.215   1.251   1.215   1.609   1.609   1.609
163   L        -0.619  -0.619  -0.619  -0.959  -0.959  -0.959  -0.619  -0.619  -0.619
164   R        -0.619  -0.619  -0.619  -0.311  -0.275  -0.311  -0.619  -0.619  -0.619
165   S         1.609   1.609   1.609   1.298   1.266   1.298   1.609   1.609   1.609
166   K        -0.619  -0.619  -0.619  -0.449  -0.402  -0.449  -0.619  -0.619  -0.619
167   K        -0.619  -0.619  -0.619  -0.347  -0.333  -0.347  -0.619  -0.619  -0.619
168   N        -0.619  -0.619  -0.619  -0.514  -0.512  -0.514  -0.619  -0.619  -0.619
169   L         1.609   1.609   1.609   1.215   1.251   1.215   1.609   1.609   1.609
170   A        -0.619  -0.619  -0.619  -0.384  -0.363  -0.384  -0.619  -0.619  -0.619
171   S        -0.619  -0.619  -0.619  -0.846  -0.882  -0.846  -0.619  -0.619  -0.619
172   G         1.609   1.609   1.609   1.749   1.767   1.749   1.609   1.609   1.609
173   T        -0.619  -0.619  -0.619  -0.458  -0.452  -0.458  -0.619  -0.619  -0.619
174   S        -0.619  -0.619  -0.619  -0.756  -0.773  -0.756  -0.619  -0.619  -0.619
175   V         1.609   1.609   1.609   1.527   1.485   1.527   1.609   1.609   1.609
176   I        -0.619  -0.619  -0.619  -0.970  -0.937  -0.970  -0.619  -0.619  -0.619
177   E        -0.619  -0.619  -0.619  -0.338  -0.343  -0.338  -0.619  -0.619  -0.619
178   V         1.609   1.609   1.609   1.527   1.485   1.527   1.609   1.609   1.609
179   N        -0.619  -0.619  -0.619  -0.846  -0.882  -0.846  -0.619  -0.619  -0.619
180   P        -0.619  -0.619  -0.619  -0.458  -0.472  -0.458  -0.619  -0.619  -0.619
181   G        -0.619  -0.619  -0.619  -0.311  -0.304  -0.311  -0.619  -0.619  -0.619
182   N        -0.619  -0.619  -0.619  -0.543  -0.553  -0.543  -0.619  -0.619  -0.619
183   C        -0.619  -0.619  -0.619  -0.107  -0.094  -0.107  -0.619  -0.619  -0.619
184   N        -0.619  -0.619  -0.619  -0.467  -0.482  -0.467  -0.619  -0.619  -0.619
185   E        -0.619  -0.619  -0.619  -0.543  -0.553  -0.543  -0.619  -0.619  -0.619
186   F         1.609   1.609   1.609   1.749   1.739   1.749   1.609   1.609   1.609
187   L        -0.619  -0.619  -0.619  -0.736  -0.709  -0.736  -0.619  -0.619  -0.619
188   I         1.609   1.609   1.609   1.514   1.514   1.514   1.609   1.609   1.609
189   C         1.609   1.609   1.609   1.965   1.971   1.965   1.609   1.609   1.609
190   F        -0.619  -0.619  -0.619  -0.786  -0.762  -0.786  -0.619  -0.619  -0.619
191   I         1.609   1.609   1.609   1.514   1.514   1.514   1.609   1.609   1.609
192   N         1.609   1.609   1.609   1.593   1.571   1.593   1.609   1.609   1.609
193   L        -0.619  -0.619  -0.619  -0.786  -0.762  -0.786  -0.619  -0.619  -0.619
194   V        -0.619  -0.619  -0.619  -0.897  -0.948  -0.897  -0.619  -0.619  -0.619
195   Y        -0.619  -0.619  -0.619  -0.687  -0.667  -0.687  -0.619  -0.619  -0.619
196   D         1.609   1.609   1.609   1.606   1.585   1.606   1.609   1.609   1.609
197   G        -0.619  -0.619  -0.619  -0.727  -0.730  -0.727  -0.619  -0.619  -0.619
198   S         1.609   1.609   1.609   1.298   1.266   1.298   1.609   1.609   1.609
199   W         1.609   1.609   1.609   1.990   1.997   1.990   1.609   1.609   1.609
200   S        -0.619  -0.619  -0.619  -0.846  -0.882  -0.846  -0.619  -0.619  -0.619
201   S        -0.619  -0.619  -0.619  -0.677  -0.678  -0.677  -0.619  -0.619  -0.619
202   I         1.609   1.609   1.609   1.514   1.514   1.514   1.609   1.609   1.609
203   D         1.609   1.609   1.609   1.606   1.585   1.606   1.609   1.609   1.609
204   T        -0.619  -0.619  -0.619  -0.756  -0.773  -0.756  -0.619  -0.619  -0.619
205   E        -0.619  -0.619  -0.619  -0.590  -0.615  -0.590  -0.619  -0.619  -0.619
206   K         1.609   1.609   1.609   1.619   1.627   1.619   1.609   1.609   1.609
207   S        -0.619  -0.619  -0.619  -0.677  -0.699  -0.677  -0.619  -0.619  -0.619
208   V         1.609   1.609   1.609   1.527   1.485   1.527   1.609   1.609   1.609
209   T        -0.619  -0.619  -0.619  -0.384  -0.363  -0.384  -0.619  -0.619  -0.619
210   I         1.609   1.609   1.609   1.514   1.514   1.514   1.609   1.609   1.609
211   K        -0.619  -0.619  -0.619  -0.826  -0.838  -0.826  -0.619  -0.619  -0.619
212   M        -0.619  -0.619  -0.619  -0.458  -0.442  -0.458  -0.619  -0.619  -0.619
213   T         1.609   1.609   1.609   1.711   1.711   1.711   1.609   1.609   1.609
214   Y        -0.619  -0.619  -0.619  -0.629  -0.657  -0.629  -0.619  -0.619  -0.619
215   N         1.609   1.609   1.609   1.593   1.571   1.593   1.609   1.609   1.609
216   D         1.609   1.609   1.609   1.606   1.585   1.606   1.609   1.609   1.609
217   K        -0.619  -0.619  -0.619  -0.887  -0.849  -0.887  -0.619  -0.619  -0.619
218   L        -0.619  -0.619  -0.619  -0.970  -0.937  -0.970  -0.619  -0.619  -0.619
219   D        -0.619  -0.619  -0.619  -0.458  -0.472  -0.458  -0.619  -0.619  -0.619
220   P        -0.619  -0.619  -0.619  -0.393  -0.372  -0.393  -0.619  -0.619  -0.619
221   D        -0.619  -0.619  -0.619  -0.458  -0.472  -0.458  -0.619  -0.619  -0.619
222   M        -0.619  -0.619  -0.619  -0.384  -0.363  -0.384  -0.619  -0.619  -0.619
223   L        -0.619  -0.619  -0.619  -0.600  -0.563  -0.600  -0.619  -0.619  -0.619
224   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
225   H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
226   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
227   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
228   N        -0.619  -0.619  -0.619  -0.619  -0.646  -0.619  -0.619  -0.619  -0.619
229   Q        -0.619  -0.619  -0.619  -0.736  -0.709  -0.736  -0.619  -0.619  -0.619
230   M        -0.619  -0.619  -0.619  -0.458  -0.442  -0.458  -0.619  -0.619  -0.619
231   T         1.609   1.609   1.609   1.711   1.711   1.711   1.609   1.609   1.609
232   P        -0.619  -0.619  -0.619  -0.402  -0.402  -0.402  -0.619  -0.619  -0.619
233   Q        -0.619  -0.619  -0.619  -0.458  -0.472  -0.458  -0.619  -0.619  -0.619
234   V        -0.619  -0.619  -0.619  -0.668  -0.709  -0.668  -0.619  -0.619  -0.619
235   V        -0.619  -0.619  -0.619  -0.959  -0.959  -0.959  -0.619  -0.619  -0.619
236   K        -0.619  -0.619  -0.619  -0.610  -0.615  -0.610  -0.619  -0.619  -0.619
237   A        -0.619  -0.619  -0.619  -0.736  -0.688  -0.736  -0.619  -0.619  -0.619
238   L         1.609   1.609   1.609   1.215   1.251   1.215   1.609   1.609   1.609
239   N        -0.619  -0.619  -0.619  -0.846  -0.882  -0.846  -0.619  -0.619  -0.619
240   T        -0.619  -0.619  -0.619  -0.384  -0.382  -0.384  -0.619  -0.619  -0.619
241   V        -0.619  -0.619  -0.619  -0.562  -0.574  -0.562  -0.619  -0.619  -0.619
242   S        -0.619  -0.619  -0.619  -0.677  -0.657  -0.677  -0.619  -0.619  -0.619
243   D         1.609   1.609   1.609   1.606   1.585   1.606   1.609   1.609   1.609
244   G        -0.619  -0.619  -0.619  -0.505  -0.502  -0.505  -0.619  -0.619  -0.619
245   L         1.609   1.609   1.609   1.215   1.251   1.215   1.609   1.609   1.609
246   F         1.609   1.609   1.609   1.749   1.739   1.749   1.609   1.609   1.609
247   Q        -0.619  -0.619  -0.619  -0.677  -0.699  -0.677  -0.619  -0.619  -0.619
248   I        -0.619  -0.619  -0.619  -0.970  -0.937  -0.970  -0.619  -0.619  -0.619
249   V         1.609   1.609   1.609   1.527   1.485   1.527   1.609   1.609   1.609
250   S         1.609   1.609   1.609   1.298   1.266   1.298   1.609   1.609   1.609
251   D        -0.619  -0.619  -0.619  -0.458  -0.452  -0.458  -0.619  -0.619  -0.619
252   T        -0.619  -0.619  -0.619  -0.533  -0.543  -0.533  -0.619  -0.619  -0.619
253   T        -0.619  -0.619  -0.619  -0.756  -0.773  -0.756  -0.619  -0.619  -0.619
254   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
255   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
256   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
257   L         1.609   1.609   1.609   1.215   1.251   1.215   1.609   1.609   1.609
258   L        -0.619  -0.619  -0.619  -0.629  -0.594  -0.629  -0.619  -0.619  -0.619
259   Q        -0.619  -0.619  -0.619  -0.311  -0.294  -0.311  -0.619  -0.619  -0.619
260   M        -0.619  -0.619  -0.619  -0.668  -0.625  -0.668  -0.619  -0.619  -0.619
261   E        -0.619  -0.619  -0.619  -0.533  -0.543  -0.533  -0.619  -0.619  -0.619
262   S        -0.619  -0.619  -0.619  -0.897  -0.948  -0.897  -0.619  -0.619  -0.619
263   D         1.609   1.609   1.609   1.606   1.585   1.606   1.609   1.609   1.609
264   R        -0.619  -0.619  -0.619  -0.213  -0.169  -0.213  -0.619  -0.619  -0.619
265   R         1.609   1.609   1.609   1.813   1.863   1.813   1.609   1.609   1.609
266   D        -0.619  -0.619  -0.619  -0.619  -0.646  -0.619  -0.619  -0.619  -0.619
267   I        -0.619  -0.619  -0.619  -0.970  -0.937  -0.970  -0.619  -0.619  -0.619
268   N         1.609   1.609   1.609   1.593   1.571   1.593   1.609   1.609   1.609
269   E         1.609   1.609   1.609   1.711   1.711   1.711   1.609   1.609   1.609
270   A        -0.619  -0.619  -0.619  -0.677  -0.678  -0.677  -0.619  -0.619  -0.619
271   T         1.609   1.609   1.609   1.711   1.711   1.711   1.609   1.609   1.609
272   Y        -0.619  -0.619  -0.619  -0.311  -0.323  -0.311  -0.619  -0.619  -0.619
273   S         1.609   1.609   1.609   1.298   1.266   1.298   1.609   1.609   1.609
274   Y         1.609   1.609   1.609   1.877   1.863   1.877   1.609   1.609   1.609
275   L         1.609   1.609   1.609   1.215   1.251   1.215   1.609   1.609   1.609
276   I        -0.619  -0.619  -0.619  -0.970  -0.937  -0.970  -0.619  -0.619  -0.619
277   V        -0.619  -0.619  -0.619  -0.514  -0.523  -0.514  -0.619  -0.619  -0.619
278   G        -0.619  -0.619  -0.619  -0.496  -0.472  -0.496  -0.619  -0.619  -0.619
279   F        -0.619  -0.619  -0.619  -0.562  -0.594  -0.562  -0.619  -0.619  -0.619
280   V        -0.619  -0.619  -0.619  -0.590  -0.615  -0.590  -0.619  -0.619  -0.619
281   S        -0.619  -0.619  -0.619  -0.908  -0.926  -0.908  -0.619  -0.619  -0.619
282   L         1.609   1.609   1.609   1.215   1.251   1.215   1.609   1.609   1.609
283   M        -0.619  -0.619  -0.619  -0.293  -0.284  -0.293  -0.619  -0.619  -0.619
284   V        -0.619  -0.619  -0.619  -0.402  -0.422  -0.402  -0.619  -0.619  -0.619
285   A        -0.619  -0.619  -0.619  -0.524  -0.502  -0.524  -0.619  -0.619  -0.619
286   Q        -0.619  -0.619  -0.619  -0.524  -0.523  -0.524  -0.619  -0.619  -0.619
287   L        -0.619  -0.619  -0.619  -0.786  -0.741  -0.786  -0.619  -0.619  -0.619
288   I        -0.619  -0.619  -0.619  -0.736  -0.762  -0.736  -0.619  -0.619  -0.619
289   S        -0.619  -0.619  -0.619  -0.562  -0.574  -0.562  -0.619  -0.619  -0.619
290   N        -0.619  -0.619  -0.619  -0.366  -0.372  -0.366  -0.619  -0.619  -0.619
291   I        -0.619  -0.619  -0.619  -0.970  -0.937  -0.970  -0.619  -0.619  -0.619
292   I        -0.619  -0.619  -0.619  -0.970  -0.937  -0.970  -0.619  -0.619  -0.619
293   V         1.609   1.609   1.609   1.527   1.485   1.527   1.609   1.609   1.609
294   T        -0.619  -0.619  -0.619  -0.430  -0.432  -0.430  -0.619  -0.619  -0.619
295   T        -0.619  -0.619  -0.619  -0.329  -0.314  -0.329  -0.619  -0.619  -0.619
296   Y        -0.619  -0.619  -0.619  -0.477  -0.482  -0.477  -0.619  -0.619  -0.619
297   L         1.609   1.609   1.609   1.215   1.251   1.215   1.609   1.609   1.609
298   I        -0.619  -0.619  -0.619  -0.970  -0.937  -0.970  -0.619  -0.619  -0.619
299   I        -0.619  -0.619  -0.619  -0.477  -0.482  -0.477  -0.619  -0.619  -0.619
300   K        -0.619  -0.619  -0.619  -0.449  -0.402  -0.449  -0.619  -0.619  -0.619
301   I         1.609   1.609   1.609   1.514   1.514   1.514   1.609   1.609   1.609
302   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
303   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
304   K         1.609   1.609   1.609   1.619   1.627   1.619   1.609   1.609   1.609
305   S        -0.619  -0.619  -0.619  -0.727  -0.730  -0.727  -0.619  -0.619  -0.619
306   N        -0.619  -0.619  -0.619  -0.467  -0.482  -0.467  -0.619  -0.619  -0.619
307   P         1.609   1.609   1.609   1.889   1.903   1.889   1.609   1.609   1.609
308   S        -0.619  -0.619  -0.619  -0.756  -0.773  -0.756  -0.619  -0.619  -0.619
309   S        -0.619  -0.619  -0.619  -0.826  -0.838  -0.826  -0.619  -0.619  -0.619
310   H        -0.619  -0.619  -0.619  -0.366  -0.372  -0.366  -0.619  -0.619  -0.619
311   I        -0.619  -0.619  -0.619  -0.668  -0.657  -0.668  -0.619  -0.619  -0.619
312   K        -0.619  -0.619  -0.619  -0.610  -0.615  -0.610  -0.619  -0.619  -0.619
313   K         1.609   1.609   1.609   1.619   1.627   1.619   1.609   1.609   1.609
314   K        -0.619  -0.619  -0.619  -0.668  -0.657  -0.668  -0.619  -0.619  -0.619
315   G        -0.619  -0.619  -0.619  -0.496  -0.472  -0.496  -0.619  -0.619  -0.619
316   L        -0.619  -0.619  -0.619  -0.736  -0.667  -0.736  -0.619  -0.619  -0.619
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P53117
Output conservation file - output/P53117
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
