1     M         1.763   1.786   1.960   1.996   2.030   2.289   1.975   2.011   2.298
2     T         0.280   0.281   0.318   0.162   0.158   0.177  -0.001  -0.009  -0.015
3     T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     T        -1.147  -1.231  -1.098  -1.064  -1.204  -1.050  -0.986  -1.049  -0.877
6     T         0.193   0.106  -0.023   0.181   0.068  -0.156   0.090  -0.023  -0.207
7     V        -0.109   0.014  -0.093  -0.268  -0.082  -0.236  -0.340  -0.165  -0.306
8     F         0.729   0.684   0.465   0.736   0.680   0.365   0.718   0.639   0.233
9     V         0.561   0.629   0.443   0.478   0.546   0.292   0.421   0.502   0.191
10    S         0.939   0.915   0.946   0.845   0.803   0.788   0.785   0.721   0.646
11    G         1.763   1.786   1.960   1.792   1.824   2.089   1.975   2.011   2.298
12    A         0.577   0.439   0.102   0.647   0.480   0.026   0.685   0.487  -0.012
13    T         0.808   0.813   0.909   0.623   0.624   0.714   0.520   0.511   0.563
14    G         1.763   1.786   1.960   1.792   1.824   2.089   1.975   2.011   2.298
15    F         1.763   1.786   1.960   1.812   1.845   2.109   1.975   2.011   2.298
16    I         0.808   0.913   0.976   0.645   0.821   0.862   0.520   0.716   0.714
17    A         1.359   1.249   1.189   1.291   1.175   1.114   1.512   1.335   1.162
18    L        -0.640  -0.644  -0.554  -0.775  -0.825  -0.695  -0.770  -0.789  -0.646
19    H         0.964   0.945   0.604   1.317   1.304   0.887   1.082   1.053   0.482
20    I         0.044   0.059   0.226  -0.125  -0.130   0.108  -0.373  -0.351  -0.160
21    M        -0.477  -0.549  -0.485  -0.597  -0.700  -0.597  -0.604  -0.664  -0.574
22    N        -0.687  -0.740  -0.783  -0.652  -0.776  -0.860  -0.670  -0.746  -0.725
23    D         0.561   0.544   0.425   0.708   0.697   0.466   0.421   0.397   0.155
24    L         1.763   1.786   1.960   1.654   1.690   1.954   1.975   2.011   2.298
25    L         1.359   1.341   1.193   1.337   1.327   1.162   1.512   1.482   1.169
26    K        -0.633  -0.693  -0.732  -0.781  -0.840  -0.849  -0.670  -0.719  -0.680
27    A        -0.508  -0.467  -0.701  -0.510  -0.499  -0.767  -0.472  -0.459  -0.642
28    G         0.964   1.013   0.605   1.157   1.215   0.717   1.082   1.148   0.483
29    Y         0.655   0.660   0.850   0.621   0.615   0.885   0.189   0.176   0.427
30    T        -1.269  -1.246  -1.091  -1.281  -1.222  -0.997  -1.100  -1.073  -0.875
31    V         1.763   1.786   1.960   1.688   1.713   1.987   1.975   2.011   2.298
32    I         0.193   0.098  -0.017   0.272   0.154  -0.025   0.090  -0.031  -0.199
33    G         1.359   1.304   1.186   1.470   1.415   1.272   1.512   1.425   1.156
34    S         1.359   1.356   1.191   1.400   1.409   1.217   1.512   1.506   1.166
35    G         0.440   0.494   0.404   0.304   0.394   0.262   0.189   0.293   0.105
36    R         1.763   1.786   1.960   1.935   1.967   2.229   1.975   2.011   2.298
37    S        -0.016   0.050  -0.313   0.232   0.323  -0.144   0.024   0.117  -0.349
38    Q        -1.147  -1.217  -1.097  -1.031  -1.106  -0.974  -1.001  -1.045  -0.878
39    E        -0.907  -0.820  -0.831  -0.889  -0.770  -0.817  -0.869  -0.782  -0.762
40    K         1.763   1.786   1.960   1.642   1.676   1.942   1.975   2.011   2.298
41    N         0.440   0.438   0.379   0.233   0.235   0.157   0.189   0.184   0.060
42    D        -0.850  -0.843  -0.822  -0.876  -0.883  -0.869  -0.836  -0.843  -0.760
43    G        -1.356  -1.429  -1.315  -1.056  -1.185  -1.079  -1.067  -1.117  -0.951
44    L         0.939   0.959   0.983   0.787   0.814   0.809   0.785   0.808   0.729
45    L        -1.573  -1.615  -1.508  -1.551  -1.598  -1.398  -1.166  -1.187  -1.011
46    K        -0.481  -0.490  -0.482  -0.658  -0.646  -0.604  -0.637  -0.639  -0.576
47    K        -0.221  -0.295  -0.412  -0.244  -0.355  -0.543  -0.241  -0.341  -0.479
48    F         0.083  -0.042  -0.052   0.095  -0.034  -0.070  -0.108  -0.237  -0.266
49    N        -0.640  -0.551  -0.518  -0.757  -0.605  -0.577  -0.770  -0.669  -0.603
50    N        -1.318  -1.299  -1.107  -1.362  -1.323  -1.043  -1.138  -1.112  -0.886
51    -        -0.525  -0.545  -0.524  -0.745  -0.787  -0.718  -0.669  -0.686  -0.613
52    -        -0.655  -0.697  -0.567  -0.721  -0.802  -0.615  -0.792  -0.824  -0.657
53    -        -1.378  -1.355  -1.135  -1.599  -1.573  -1.291  -1.177  -1.149  -0.905
54    N        -0.261  -0.303  -0.412  -0.225  -0.278  -0.419  -0.373  -0.410  -0.493
55    P        -0.525  -0.660  -0.934  -0.106  -0.284  -0.704  -0.307  -0.460  -0.721
56    K         0.193   0.180  -0.004   0.194   0.203  -0.057   0.090   0.099  -0.187
57    L         0.136   0.102  -0.005   0.181   0.148  -0.026   0.057   0.024  -0.179
58    S        -1.421  -1.380  -1.284  -1.394  -1.348  -1.255  -1.133  -1.096  -0.933
59    M        -0.481  -0.532  -0.492  -0.506  -0.539  -0.441  -0.637  -0.669  -0.584
60    E         0.729   0.614   0.452   0.770   0.593   0.318   0.718   0.505   0.210
61    I         0.165   0.194   0.319  -0.080  -0.067   0.119  -0.207  -0.201  -0.039
62    V         0.715   0.790   0.910   0.370   0.500   0.638   0.322   0.462   0.565
63    E        -1.022  -0.999  -0.850  -1.203  -1.175  -0.961  -1.001  -0.979  -0.784
64    D         1.763   1.786   1.960   1.763   1.793   2.060   1.975   2.011   2.298
65    I         0.655   0.676   0.854   0.338   0.353   0.603   0.189   0.212   0.435
66    A        -0.690  -0.699  -0.558  -0.720  -0.753  -0.549  -0.836  -0.837  -0.650
67    A        -1.364  -1.337  -1.290  -1.388  -1.369  -1.279  -1.100  -1.064  -0.936
68    P        -1.002  -1.098  -1.041  -0.942  -1.064  -1.044  -0.869  -0.938  -0.831
69    N        -1.117  -1.003  -1.044  -1.089  -0.962  -0.993  -1.001  -0.917  -0.843
70    A         0.625   0.650   0.849   0.166   0.196   0.483   0.123   0.154   0.424
71    F         1.116   1.155   1.088   1.184   1.237   1.108   1.115   1.174   0.955
72    D        -0.109   0.052  -0.080  -0.230   0.004  -0.178  -0.340  -0.132  -0.293
73    E        -1.212  -1.238  -1.267  -1.149  -1.227  -1.250  -0.935  -0.977  -0.917
74    V         0.044   0.135   0.238  -0.310  -0.169  -0.056  -0.373  -0.238  -0.141
75    F         0.561   0.423   0.384   0.593   0.367   0.256   0.421   0.187   0.079
76    K        -0.595  -0.543  -0.494  -0.776  -0.703  -0.618  -0.770  -0.707  -0.595
77    K         0.924   0.830   0.559   0.959   0.854   0.486   1.026   0.881   0.406
78    H         1.763   1.786   1.960   1.940   1.975   2.235   1.975   2.011   2.298
79    G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
80    K        -0.430  -0.453  -0.481  -0.393  -0.404  -0.518  -0.530  -0.538  -0.565
81    E         0.013   0.009  -0.052  -0.117  -0.112  -0.172  -0.241  -0.244  -0.276
82    I         0.083  -0.012  -0.051   0.017  -0.106  -0.207  -0.108  -0.211  -0.265
83    K        -1.002  -1.018  -1.032  -1.018  -1.056  -1.083  -0.869  -0.885  -0.822
84    I        -0.318  -0.407  -0.437  -0.248  -0.400  -0.431  -0.472  -0.560  -0.529
85    V         0.013  -0.006  -0.058  -0.134  -0.157  -0.186  -0.241  -0.250  -0.277
86    L         0.577   0.495   0.111   0.742   0.662   0.222   0.685   0.564   0.002
87    H         1.763   1.786   1.960   1.941   1.975   2.235   1.975   2.011   2.298
88    T         0.964   0.834   0.590   1.075   0.933   0.597   1.082   0.887   0.458
89    A         1.763   1.786   1.960   1.608   1.644   1.909   1.975   2.011   2.298
90    S         1.763   1.786   1.960   1.755   1.786   2.053   1.975   2.011   2.298
91    P         1.763   1.786   1.960   1.831   1.867   2.128   1.975   2.011   2.298
92    F         1.359   1.439   1.208   1.486   1.578   1.312   1.512   1.628   1.198
93    H        -0.481  -0.402  -0.224  -0.567  -0.449  -0.219  -0.770  -0.683  -0.473
94    F         0.193   0.153  -0.007   0.390   0.324   0.140   0.090   0.030  -0.199
95    E        -0.744  -0.765  -0.777  -0.650  -0.710  -0.791  -0.704  -0.737  -0.713
96    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
97    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
98    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
99    T        -0.900  -0.874  -0.789  -1.080  -1.045  -0.938  -0.902  -0.869  -0.731
100   T        -0.024   0.029   0.213  -0.454  -0.358  -0.121  -0.472  -0.401  -0.182
101   N         0.504   0.576   0.440   0.553   0.649   0.412   0.388   0.493   0.193
102   F        -0.147  -0.168  -0.136  -0.167  -0.208  -0.187  -0.373  -0.406  -0.366
103   E        -0.012  -0.064  -0.113  -0.087  -0.184  -0.301  -0.174  -0.258  -0.331
104   K        -0.164  -0.296  -0.397  -0.170  -0.313  -0.496  -0.207  -0.337  -0.465
105   D        -0.109  -0.153  -0.075  -0.178  -0.220  -0.130  -0.340  -0.384  -0.300
106   L         0.131   0.225   0.340   0.008   0.116   0.301  -0.274  -0.139   0.001
107   L         0.964   0.871   0.588   1.012   0.914   0.538   1.082   0.946   0.454
108   T        -1.269  -1.250  -1.109  -1.283  -1.279  -1.109  -1.100  -1.081  -0.887
109   P         1.763   1.786   1.960   1.831   1.867   2.128   1.975   2.011   2.298
110   A         1.763   1.786   1.960   1.608   1.644   1.909   1.975   2.011   2.298
111   V        -0.012   0.079  -0.018  -0.088   0.037  -0.130  -0.174  -0.049  -0.206
112   N        -1.147  -1.098  -1.057  -1.034  -1.007  -0.904  -1.001  -0.970  -0.849
113   G         1.763   1.786   1.960   1.792   1.824   2.089   1.975   2.011   2.298
114   T         1.763   1.786   1.960   1.720   1.758   2.018   1.975   2.011   2.298
115   K        -0.690  -0.655  -0.544  -0.934  -0.891  -0.715  -0.836  -0.799  -0.639
116   S        -0.785  -0.792  -0.593  -1.008  -1.007  -0.759  -0.902  -0.904  -0.679
117   I         0.808   0.737   0.871   0.601   0.447   0.623   0.520   0.347   0.474
118   L         1.763   1.786   1.960   1.654   1.690   1.954   1.975   2.011   2.298
119   E         0.016   0.025   0.210  -0.309  -0.298  -0.038  -0.406  -0.404  -0.185
120   A        -0.687  -0.495  -0.713  -0.710  -0.457  -0.708  -0.670  -0.458  -0.647
121   I        -0.328  -0.310  -0.201  -0.646  -0.625  -0.481  -0.604  -0.585  -0.448
122   K        -0.318  -0.365  -0.430  -0.360  -0.405  -0.459  -0.472  -0.516  -0.522
123   K        -1.631  -1.635  -1.504  -1.555  -1.533  -1.367  -1.200  -1.190  -1.009
124   Y        -0.527  -0.591  -0.502  -0.382  -0.454  -0.349  -0.682  -0.727  -0.593
125   A         0.294   0.227   0.348  -0.029  -0.094   0.092  -0.108  -0.169  -0.003
126   A        -0.687  -0.715  -0.777  -0.592  -0.666  -0.763  -0.670  -0.711  -0.714
127   D        -0.164  -0.325  -0.412   0.033  -0.166  -0.317  -0.207  -0.386  -0.491
128   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
129   V         0.939   0.862   0.925   0.820   0.675   0.730   0.785   0.612   0.599
130   E        -0.592  -0.601  -0.720  -0.558  -0.555  -0.664  -0.604  -0.610  -0.662
131   K         0.345   0.311   0.357   0.274   0.201   0.277   0.123   0.027   0.037
132   V         0.561   0.609   0.430   0.515   0.548   0.321   0.421   0.464   0.160
133   I         1.116   1.152   1.032   1.079   1.118   0.928   1.115   1.168   0.835
134   V         0.358   0.400   0.369   0.172   0.235   0.187   0.024   0.090   0.038
135   T         1.763   1.786   1.960   1.720   1.758   2.018   1.975   2.011   2.298
136   S         1.763   1.786   1.960   1.755   1.786   2.053   1.975   2.011   2.298
137   S         1.763   1.786   1.960   1.755   1.786   2.053   1.975   2.011   2.298
138   T        -1.204  -1.130  -1.062  -1.102  -0.975  -0.937  -1.034  -0.951  -0.848
139   A         1.359   1.389   1.193   1.283   1.325   1.096   1.512   1.556   1.170
140   A         0.939   0.986   0.949   0.735   0.805   0.693   0.785   0.861   0.654
141   L        -0.318  -0.358  -0.412  -0.201  -0.255  -0.299  -0.472  -0.497  -0.499
142   V        -0.755  -0.820  -0.761  -0.675  -0.747  -0.649  -0.770  -0.801  -0.706
143   T        -0.842  -0.800  -0.786  -0.824  -0.790  -0.691  -0.869  -0.833  -0.734
144   P        -1.644  -1.593  -1.499  -1.514  -1.468  -1.298  -1.214  -1.173  -1.005
145   T        -1.543  -1.557  -1.324  -1.440  -1.442  -1.136  -1.214  -1.205  -0.959
146   D        -1.217  -1.163  -1.062  -1.207  -1.148  -0.965  -1.062  -1.014  -0.853
147   M        -2.093  -2.033  -1.862  -1.776  -1.703  -1.514  -1.366  -1.323  -1.108
148   N        -1.573  -1.598  -1.476  -1.317  -1.358  -1.198  -1.166  -1.172  -0.991
149   K         0.577   0.413   0.105   0.815   0.630   0.215   0.685   0.457  -0.007
150   G        -0.016  -0.146  -0.374   0.267   0.107  -0.279   0.024  -0.134  -0.434
151   D        -0.328  -0.273  -0.189  -0.497  -0.411  -0.313  -0.604  -0.536  -0.428
152   L        -1.573  -1.564  -1.341  -1.493  -1.502  -1.243  -1.233  -1.211  -0.969
153   V        -0.271  -0.254  -0.153  -0.541  -0.513  -0.350  -0.571  -0.539  -0.398
154   I        -1.631  -1.572  -1.362  -1.566  -1.477  -1.178  -1.266  -1.219  -0.983
155   T        -0.012  -0.009  -0.084  -0.036  -0.010  -0.164  -0.174  -0.154  -0.290
156   E         1.763   1.786   1.960   1.723   1.764   2.021   1.975   2.011   2.298
157   E        -0.897  -0.862  -0.982  -0.832  -0.805  -0.987  -0.737  -0.706  -0.776
158   S        -0.230  -0.232  -0.143  -0.397  -0.400  -0.276  -0.505  -0.504  -0.386
159   W         1.763   1.786   1.960   1.998   2.032   2.291   1.975   2.011   2.298
160   N         1.763   1.786   1.960   1.791   1.825   2.088   1.975   2.011   2.298
161   K         0.199   0.145  -0.296   0.560   0.500  -0.113   0.322   0.251  -0.324
162   D        -0.271  -0.213  -0.119  -0.405  -0.335  -0.172  -0.571  -0.493  -0.357
163   T         0.729   0.738   0.493   0.792   0.796   0.453   0.718   0.711   0.283
164   W         0.136   0.062  -0.046   0.537   0.434   0.259   0.057  -0.053  -0.235
165   D         0.083   0.089  -0.046   0.043   0.048  -0.115  -0.108  -0.115  -0.266
166   S        -0.230  -0.259  -0.175  -0.272  -0.332  -0.245  -0.505  -0.547  -0.429
167   C         0.577   0.509   0.107   0.678   0.608   0.124   0.685   0.590  -0.004
168   Q        -0.566  -0.690  -0.759  -0.471  -0.648  -0.728  -0.505  -0.645  -0.691
169   A        -1.155  -1.272  -1.256  -0.911  -1.080  -1.136  -0.872  -0.968  -0.904
170   -         0.280   0.132   0.274   0.080  -0.165   0.013  -0.001  -0.232  -0.082
171   -         0.365   0.283   0.290   0.356   0.180   0.168   0.138  -0.036  -0.065
172   N         0.939   0.969   0.939   0.917   0.959   0.841   0.785   0.827   0.630
173   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
174   A        -0.687  -0.637  -0.758  -0.595  -0.554  -0.769  -0.670  -0.639  -0.702
175   V        -0.994  -0.984  -0.839  -1.098  -1.118  -0.892  -0.968  -0.961  -0.772
176   A        -0.640  -0.661  -0.551  -0.952  -0.988  -0.842  -0.770  -0.788  -0.641
177   A        -0.440  -0.329  -0.430  -0.594  -0.418  -0.553  -0.571  -0.421  -0.505
178   Y         1.763   1.786   1.960   1.949   1.980   2.243   1.975   2.011   2.298
179   C        -1.356  -1.344  -1.286  -1.047  -1.026  -0.908  -1.067  -1.068  -0.934
180   G         0.625   0.648   0.846   0.221   0.242   0.532   0.123   0.149   0.418
181   S         1.359   1.341   1.193   1.425   1.409   1.222   1.512   1.482   1.169
182   K         1.763   1.786   1.960   1.642   1.676   1.942   1.975   2.011   2.298
183   K        -0.440  -0.314  -0.438  -0.640  -0.486  -0.647  -0.571  -0.453  -0.527
184   F        -0.109  -0.108  -0.123  -0.050  -0.079  -0.066  -0.340  -0.343  -0.349
185   A         1.763   1.786   1.960   1.608   1.644   1.909   1.975   2.011   2.298
186   E         1.763   1.786   1.960   1.723   1.764   2.021   1.975   2.011   2.298
187   K         0.577   0.495   0.111   0.710   0.614   0.155   0.685   0.564   0.002
188   T         0.136   0.198   0.017   0.048   0.148  -0.154   0.057   0.148  -0.137
189   A         0.561   0.702   0.488   0.434   0.633   0.347   0.421   0.644   0.274
190   W        -0.016   0.033  -0.320   0.429   0.512  -0.013   0.024   0.091  -0.358
191   E         0.310   0.336   0.363   0.067   0.107   0.173  -0.075  -0.042   0.023
192   F         1.116   1.057   1.007   1.229   1.151   1.061   1.115   0.997   0.781
193   L        -0.508  -0.364  -0.678  -0.402  -0.220  -0.596  -0.472  -0.305  -0.613
194   K        -0.440  -0.364  -0.440  -0.560  -0.433  -0.512  -0.571  -0.472  -0.523
195   E        -1.212  -1.121  -1.073  -1.169  -1.075  -0.950  -1.067  -0.998  -0.865
196   N        -0.336  -0.443  -0.440  -0.398  -0.504  -0.485  -0.505  -0.589  -0.530
197   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
198   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
199   S         0.358   0.346   0.352   0.110   0.091   0.132   0.024  -0.001   0.011
200   V         0.198   0.185   0.259   0.110   0.066   0.098  -0.108  -0.144  -0.106
201   K        -1.479  -1.382  -1.289  -1.358  -1.255  -1.073  -1.166  -1.092  -0.934
202   F         1.116   1.057   1.007   1.229   1.151   1.061   1.115   0.997   0.781
203   T        -1.204  -1.178  -1.083  -1.171  -1.170  -1.042  -1.034  -1.020  -0.868
204   L         0.808   0.834   0.928   0.568   0.605   0.705   0.520   0.555   0.606
205   S         0.351   0.155  -0.006   0.485   0.253  -0.016   0.355   0.089  -0.178
206   T         0.440   0.501   0.435   0.403   0.511   0.410   0.189   0.316   0.175
207   I         0.625   0.648   0.846   0.256   0.279   0.580   0.123   0.149   0.418
208   N         1.763   1.786   1.960   1.791   1.825   2.088   1.975   2.011   2.298
209   P         1.763   1.786   1.960   1.831   1.867   2.128   1.975   2.011   2.298
210   G        -0.965  -0.918  -0.839  -1.122  -1.040  -0.937  -0.968  -0.921  -0.778
211   F        -0.414  -0.441  -0.479  -0.180  -0.206  -0.351  -0.472  -0.498  -0.555
212   V         0.808   0.913   0.976   0.601   0.762   0.827   0.520   0.716   0.714
213   F         0.561   0.532   0.464   0.616   0.624   0.488   0.421   0.409   0.230
214   G         1.763   1.786   1.960   1.792   1.824   2.089   1.975   2.011   2.298
215   P         1.763   1.786   1.960   1.831   1.867   2.128   1.975   2.011   2.298
216   Q        -0.777  -0.854  -0.799  -0.605  -0.675  -0.603  -0.803  -0.850  -0.738
217   M        -0.850  -0.848  -0.799  -0.903  -0.908  -0.855  -0.836  -0.828  -0.737
218   F        -0.690  -0.661  -0.561  -0.825  -0.755  -0.622  -0.836  -0.807  -0.654
219   A        -1.029  -1.043  -0.869  -1.199  -1.192  -0.947  -1.001  -1.001  -0.796
220   D        -1.147  -1.186  -1.076  -1.106  -1.136  -0.967  -1.001  -1.020  -0.861
221   S        -0.566  -0.713  -0.759  -0.415  -0.639  -0.790  -0.505  -0.658  -0.689
222   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
223   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
224   K        -1.002  -0.927  -0.837  -1.064  -0.975  -0.820  -1.001  -0.941  -0.777
225   H        -1.326  -1.347  -1.267  -1.279  -1.296  -1.176  -1.067  -1.072  -0.922
226   G        -0.336  -0.329  -0.420  -0.492  -0.457  -0.517  -0.505  -0.483  -0.510
227   I         0.808   0.825   0.900   0.568   0.589   0.651   0.520   0.537   0.541
228   N         1.763   1.786   1.960   1.791   1.825   2.088   1.975   2.011   2.298
229   T         1.359   1.439   1.208   1.390   1.488   1.212   1.512   1.628   1.198
230   S         1.763   1.786   1.960   1.755   1.786   2.053   1.975   2.011   2.298
231   S         0.345   0.393   0.380   0.299   0.361   0.266   0.123   0.179   0.078
232   G        -0.288  -0.290  -0.199  -0.411  -0.399  -0.287  -0.538  -0.537  -0.437
233   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
234   I        -0.164  -0.113  -0.353  -0.037   0.040  -0.297  -0.207  -0.139  -0.417
235   V        -0.481  -0.505  -0.460  -0.595  -0.626  -0.536  -0.637  -0.655  -0.553
236   S        -1.147  -1.152  -1.059  -1.083  -1.059  -0.955  -1.001  -0.991  -0.850
237   E        -2.087  -2.035  -1.854  -1.989  -1.936  -1.681  -1.365  -1.325  -1.104
238   L        -0.230  -0.215  -0.143  -0.597  -0.591  -0.468  -0.505  -0.497  -0.384
239   I         0.561   0.525   0.404   0.481   0.391   0.241   0.421   0.311   0.109
240   H        -1.212  -1.150  -1.092  -1.226  -1.144  -1.005  -1.067  -1.018  -0.877
241   S        -0.603  -0.653  -0.549  -0.755  -0.841  -0.708  -0.737  -0.791  -0.640
242   K         0.351   0.267   0.080   0.393   0.304   0.031   0.355   0.252  -0.044
243   V        -0.508  -0.531  -0.704  -0.307  -0.345  -0.609  -0.472  -0.506  -0.642
244   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
245   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
246   G        -0.221  -0.302  -0.402  -0.066  -0.176  -0.388  -0.241  -0.330  -0.467
247   G        -0.842  -0.871  -0.797  -0.799  -0.834  -0.732  -0.869  -0.873  -0.738
248   E        -1.299  -1.208  -1.252  -1.151  -1.009  -1.143  -1.034  -0.948  -0.908
249   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
250   F        -0.503  -0.562  -0.511  -0.487  -0.560  -0.510  -0.644  -0.692  -0.603
251   Y        -1.930  -1.910  -1.709  -1.773  -1.732  -1.503  -1.328  -1.302  -1.072
252   N        -1.217  -1.200  -1.090  -1.147  -1.128  -1.013  -1.062  -1.038  -0.873
253   Y        -1.668  -1.617  -1.510  -1.429  -1.378  -1.251  -1.233  -1.190  -1.014
254   C        -0.373  -0.463  -0.685  -0.237  -0.356  -0.636  -0.274  -0.391  -0.611
255   G        -0.373  -0.460  -0.690  -0.037  -0.146  -0.461  -0.274  -0.376  -0.612
256   P        -1.935  -1.883  -1.697  -1.559  -1.505  -1.258  -1.332  -1.291  -1.067
257   F        -0.481  -0.504  -0.445  -0.337  -0.335  -0.206  -0.637  -0.649  -0.537
258   I         0.345   0.353   0.367   0.287   0.259   0.272   0.123   0.106   0.055
259   D         1.763   1.786   1.960   1.763   1.793   2.060   1.975   2.011   2.298
260   V         1.763   1.786   1.960   1.688   1.713   1.987   1.975   2.011   2.298
261   R         1.763   1.786   1.960   1.935   1.967   2.229   1.975   2.011   2.298
262   D         1.359   1.381   1.196   1.446   1.474   1.274   1.512   1.543   1.175
263   V         0.808   0.913   0.976   0.687   0.833   0.925   0.520   0.716   0.714
264   S         1.359   1.356   1.191   1.288   1.295   1.109   1.512   1.506   1.166
265   K         0.013  -0.010  -0.053  -0.101  -0.134  -0.153  -0.241  -0.264  -0.277
266   A         0.729   0.812   0.565   0.664   0.780   0.449   0.718   0.846   0.415
267   H         1.763   1.786   1.960   1.941   1.975   2.235   1.975   2.011   2.298
268   L        -0.069  -0.076  -0.137  -0.138  -0.166  -0.330  -0.207  -0.227  -0.354
269   V        -1.174  -1.234  -1.085  -1.191  -1.236  -0.995  -1.034  -1.059  -0.870
270   A         1.116   1.195   1.154   1.007   1.114   1.069   1.115   1.244   1.090
271   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
272   I         0.235   0.237   0.288   0.021   0.025   0.068  -0.075  -0.074  -0.064
273   E        -1.147  -0.944  -1.030  -1.127  -0.837  -0.949  -1.001  -0.815  -0.821
274   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
275   P        -1.002  -1.034  -1.037  -0.875  -0.923  -0.956  -0.869  -0.888  -0.828
276   E        -0.165  -0.138  -0.130  -0.410  -0.390  -0.355  -0.439  -0.424  -0.369
277   C        -0.603  -0.620  -0.540  -0.763  -0.788  -0.675  -0.737  -0.742  -0.630
278   T        -0.839  -1.001  -1.033  -0.641  -0.857  -0.954  -0.704  -0.842  -0.822
279   G        -0.165  -0.097  -0.094  -0.216  -0.146  -0.092  -0.439  -0.370  -0.328
280   Q        -0.568  -0.565  -0.486  -0.593  -0.586  -0.454  -0.737  -0.718  -0.585
281   R         1.763   1.786   1.960   1.935   1.967   2.229   1.975   2.011   2.298
282   L         0.964   0.834   0.590   1.037   0.904   0.615   1.082   0.887   0.458
283   V        -0.546  -0.527  -0.484  -0.583  -0.550  -0.443  -0.704  -0.665  -0.579
284   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
285   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
286   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
287   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
288   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
289   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
290   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
291   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
292   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
293   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
294   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
295   L         0.351   0.235   0.060   0.435   0.299   0.041   0.355   0.210  -0.073
296   S        -1.147  -1.103  -1.058  -0.921  -0.908  -0.874  -1.001  -0.975  -0.850
297   E        -1.212  -1.215  -1.106  -1.346  -1.367  -1.225  -1.067  -1.062  -0.887
298   G        -0.012   0.145  -0.052  -0.006   0.237  -0.107  -0.174   0.053  -0.246
299   L        -0.525  -0.696  -0.954  -0.271  -0.501  -0.902  -0.307  -0.501  -0.740
300   F         0.964   1.080   0.626   1.184   1.312   0.788   1.082   1.243   0.519
301   C        -0.592  -0.642  -0.534  -0.399  -0.518  -0.457  -0.670  -0.739  -0.617
302   C        -0.907  -0.877  -0.817  -0.900  -0.850  -0.790  -0.869  -0.834  -0.749
303   Q         0.351   0.235   0.060   0.655   0.535   0.246   0.355   0.210  -0.073
304   E        -0.566  -0.599  -0.740  -0.367  -0.415  -0.613  -0.505  -0.545  -0.672
305   I         0.083   0.115  -0.034   0.071   0.117  -0.060  -0.108  -0.067  -0.246
306   V        -0.477  -0.565  -0.471  -0.635  -0.719  -0.614  -0.604  -0.674  -0.559
307   D        -0.221  -0.300  -0.398  -0.044  -0.145  -0.337  -0.241  -0.318  -0.459
308   I         0.351   0.253   0.002   0.529   0.383   0.010   0.355   0.207  -0.171
309   L        -0.690  -0.629  -0.540  -0.951  -0.883  -0.703  -0.836  -0.776  -0.633
310   N         1.116   0.995   1.000   1.206   1.041   1.024   1.115   0.879   0.765
311   E        -0.318  -0.248  -0.402  -0.426  -0.330  -0.440  -0.472  -0.388  -0.490
312   E        -0.447  -0.441  -0.248  -0.766  -0.756  -0.489  -0.731  -0.728  -0.500
313   F        -0.147   0.034  -0.076  -0.214   0.067  -0.133  -0.373  -0.126  -0.278
314   P         1.359   1.381   1.196   1.512   1.546   1.333   1.512   1.543   1.175
315   Q        -0.012  -0.079  -0.106  -0.004  -0.076  -0.150  -0.174  -0.250  -0.324
316   L        -0.221  -0.313  -0.408  -0.156  -0.263  -0.424  -0.241  -0.335  -0.469
317   K        -0.373  -0.426  -0.676  -0.170  -0.247  -0.561  -0.274  -0.341  -0.597
318   G         1.116   0.995   1.000   1.180   1.000   0.961   1.115   0.879   0.765
319   K         0.577   0.531   0.131   0.678   0.616   0.097   0.685   0.609   0.031
320   I         1.359   1.304   1.186   1.453   1.392   1.245   1.512   1.425   1.156
321   A         0.345   0.354   0.366   0.171   0.168   0.158   0.123   0.107   0.055
322   T        -0.813  -0.751  -0.562  -1.042  -0.954  -0.708  -0.935  -0.872  -0.655
323   G         0.577   0.488   0.116   0.847   0.742   0.265   0.685   0.553   0.009
324   E        -1.421  -1.379  -1.276  -1.342  -1.299  -1.161  -1.133  -1.096  -0.927
325   P         0.351   0.235   0.060   0.578   0.444   0.151   0.355   0.210  -0.073
326   A        -0.850  -0.859  -0.787  -0.916  -0.926  -0.875  -0.836  -0.836  -0.726
327   T        -1.147  -1.091  -1.029  -1.123  -1.020  -0.960  -1.001  -0.929  -0.821
328   G        -0.900  -0.926  -0.809  -0.811  -0.863  -0.714  -0.902  -0.909  -0.746
329   P        -1.059  -1.119  -1.071  -1.002  -1.099  -1.093  -0.902  -0.959  -0.859
330   S        -0.992  -1.010  -0.862  -1.205  -1.207  -0.956  -0.986  -0.991  -0.794
331   F        -1.248  -1.286  -1.283  -1.128  -1.211  -1.200  -0.986  -1.017  -0.929
332   L        -0.817  -0.882  -1.024  -0.689  -0.799  -1.054  -0.644  -0.725  -0.811
333   E        -1.380  -1.382  -1.263  -1.429  -1.424  -1.260  -1.100  -1.085  -0.918
334   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
335   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
336   N        -1.269  -1.215  -1.105  -1.288  -1.218  -1.033  -1.100  -1.062  -0.887
337   S        -1.636  -1.626  -1.640  -1.342  -1.334  -1.412  -1.100  -1.094  -1.027
338   C        -0.850  -0.720  -0.785  -0.779  -0.611  -0.704  -0.836  -0.710  -0.724
339   K        -0.965  -0.874  -0.808  -0.946  -0.859  -0.741  -0.968  -0.880  -0.748
340   F        -1.269  -1.268  -1.117  -1.021  -1.054  -0.835  -1.100  -1.092  -0.895
341   D         0.351   0.409   0.096   0.554   0.628   0.228   0.355   0.440  -0.020
342   N         0.199   0.344  -0.248   0.534   0.695  -0.036   0.322   0.500  -0.263
343   S        -0.325  -0.301  -0.208  -0.525  -0.496  -0.417  -0.571  -0.543  -0.449
344   K        -1.820  -1.759  -1.665  -1.752  -1.694  -1.532  -1.266  -1.221  -1.049
345   T         0.939   0.897   0.918   0.845   0.773   0.731   0.785   0.684   0.583
346   K        -0.777  -0.705  -0.737  -0.759  -0.670  -0.690  -0.803  -0.735  -0.684
347   K        -0.535  -0.618  -0.509  -0.612  -0.724  -0.593  -0.637  -0.722  -0.598
348   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
349   L         0.520   0.561   0.111   0.617   0.669   0.061   0.608   0.659   0.002
350   L         0.729   0.828   0.571   0.725   0.857   0.530   0.718   0.867   0.425
351   G        -0.727  -0.656  -0.543  -0.901  -0.797  -0.640  -0.869  -0.793  -0.635
352   F        -0.393  -0.304  -0.204  -0.550  -0.417  -0.276  -0.670  -0.563  -0.445
353   Q        -0.785  -0.743  -0.559  -0.970  -0.912  -0.675  -0.902  -0.860  -0.651
354   F        -0.184  -0.187  -0.151  -0.103  -0.118  -0.046  -0.472  -0.481  -0.394
355   Y        -0.261  -0.358  -0.426  -0.100  -0.207  -0.270  -0.373  -0.470  -0.509
356   N        -0.748  -0.707  -0.543  -0.846  -0.800  -0.586  -0.869  -0.829  -0.632
357   L         0.351   0.239   0.022   0.413   0.287  -0.055   0.355   0.217  -0.141
358   K        -0.373  -0.215  -0.645  -0.122   0.087  -0.492  -0.274  -0.081  -0.568
359   D        -0.690  -0.674  -0.557  -0.813  -0.789  -0.593  -0.836  -0.824  -0.650
360   C        -0.440  -0.543  -0.489  -0.403  -0.503  -0.409  -0.571  -0.669  -0.581
361   I         0.358   0.282   0.369   0.166   0.086   0.232   0.024  -0.058   0.035
362   V        -0.937  -0.827  -0.814  -0.994  -0.841  -0.817  -0.935  -0.819  -0.750
363   D         1.763   1.786   1.960   1.763   1.793   2.060   1.975   2.011   2.298
364   T         0.165   0.194   0.319  -0.048  -0.044   0.122  -0.207  -0.201  -0.039
365   A         0.100   0.117   0.237  -0.297  -0.291  -0.143  -0.274  -0.267  -0.143
366   A        -0.204  -0.134  -0.179  -0.433  -0.343  -0.474  -0.406  -0.326  -0.412
367   Q         0.577   0.439   0.102   0.936   0.772   0.282   0.685   0.487  -0.012
368   M        -0.603  -0.657  -0.550  -0.427  -0.544  -0.377  -0.737  -0.794  -0.641
369   L        -0.718  -0.784  -0.967  -0.506  -0.594  -0.851  -0.538  -0.612  -0.755
370   E        -0.687  -0.579  -0.724  -0.664  -0.500  -0.750  -0.670  -0.549  -0.658
371   V        -1.481  -1.476  -1.316  -1.302  -1.300  -1.063  -1.176  -1.160  -0.954
372   Q        -1.668  -1.688  -1.509  -1.519  -1.545  -1.288  -1.233  -1.231  -1.013
373   N        -1.421  -1.386  -1.290  -1.390  -1.362  -1.163  -1.133  -1.096  -0.935
374   E        -0.129  -0.076  -0.089  -0.159  -0.057  -0.100  -0.321  -0.232  -0.285
375   A        -1.601  -1.596  -1.379  -1.563  -1.592  -1.363  -1.240  -1.228  -0.992
376   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
377   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
378   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
379   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
380   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
381   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
382   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
383   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P53111
Output conservation file - output/P53111
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
