1     M         1.537   1.549   1.659   1.772   1.787   1.962   1.696   1.714   1.896
2     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     T         0.129   0.135  -0.077   0.335   0.339   0.008   0.080   0.088  -0.235
9     V        -1.071  -1.039  -1.064  -1.027  -0.983  -1.064  -0.948  -0.912  -0.903
10    E        -1.630  -1.614  -1.474  -1.424  -1.389  -1.193  -1.303  -1.285  -1.109
11    Y        -1.308  -1.285  -1.155  -1.216  -1.197  -0.987  -1.183  -1.159  -0.989
12    T        -0.659  -0.617  -0.686  -0.601  -0.531  -0.689  -0.703  -0.649  -0.719
13    A        -1.222  -1.233  -1.134  -1.156  -1.185  -1.029  -1.103  -1.112  -0.971
14    S        -0.251  -0.204  -0.207  -0.246  -0.171  -0.160  -0.503  -0.433  -0.433
15    D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
19    Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
20    Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
21    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
22    E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
23    V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
24    N        -0.818  -0.811  -0.727  -0.951  -0.947  -0.814  -0.895  -0.884  -0.766
25    E        -1.308  -1.302  -1.155  -1.335  -1.322  -1.106  -1.183  -1.173  -0.989
26    Q        -0.818  -0.800  -0.748  -0.869  -0.844  -0.774  -0.895  -0.871  -0.791
27    I         0.652   0.672   0.572   0.538   0.571   0.335   0.545   0.576   0.345
28    A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
29    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
30    N         1.537   1.549   1.659   1.558   1.574   1.751   1.696   1.714   1.896
31    K        -0.818  -0.800  -0.748  -0.810  -0.775  -0.732  -0.895  -0.871  -0.791
32    A        -0.143  -0.112  -0.177  -0.111  -0.057  -0.174  -0.319  -0.274  -0.384
33    H        -0.143  -0.151  -0.196  -0.165  -0.187  -0.355  -0.319  -0.331  -0.412
34    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
35    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
36    E        -0.143  -0.149  -0.173  -0.163  -0.168  -0.239  -0.319  -0.328  -0.379
37    S         0.347   0.351   0.461   0.163   0.169   0.329  -0.031  -0.030   0.122
38    L         0.347   0.351   0.461  -0.135  -0.135   0.048  -0.031  -0.030   0.122
39    T        -0.818  -0.824  -0.743  -0.871  -0.883  -0.786  -0.895  -0.900  -0.784
40    H        -0.143  -0.136  -0.167  -0.080  -0.076  -0.170  -0.319  -0.309  -0.370
41    P         0.652   0.656   0.570   0.739   0.747   0.551   0.545   0.548   0.340
42    G         1.537   1.549   1.659   1.655   1.674   1.847   1.696   1.714   1.896
43    S         0.652   0.651   0.574   0.733   0.732   0.598   0.545   0.540   0.349
44    K        -0.143  -0.151  -0.196  -0.145  -0.160  -0.206  -0.319  -0.331  -0.412
45    V         1.537   1.549   1.659   1.629   1.644   1.821   1.696   1.714   1.896
46    T         0.652   0.651   0.574   0.743   0.742   0.585   0.545   0.540   0.349
47    F         0.347   0.351   0.461   0.005   0.007   0.155  -0.031  -0.030   0.122
48    P        -0.143  -0.132  -0.179  -0.103  -0.084  -0.215  -0.319  -0.303  -0.388
49    I        -1.308  -1.302  -1.155  -1.296  -1.284  -1.067  -1.183  -1.173  -0.989
50    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
51    D        -0.720  -0.733  -0.710  -0.834  -0.851  -0.784  -0.801  -0.820  -0.752
52    Q        -0.152  -0.184  -0.182  -0.051  -0.097  -0.112  -0.360  -0.398  -0.396
53    D        -0.720  -0.729  -0.701  -0.767  -0.777  -0.744  -0.801  -0.809  -0.742
54    I        -0.152  -0.187  -0.176  -0.287  -0.351  -0.363  -0.360  -0.422  -0.392
55    S         0.479   0.492   0.497   0.479   0.511   0.471   0.227   0.247   0.197
56    A        -1.203  -1.152  -1.109  -1.148  -1.079  -1.000  -1.095  -1.048  -0.950
57    T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
58    P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
59    Q        -0.251  -0.217  -0.204  -0.312  -0.251  -0.276  -0.503  -0.452  -0.431
60    N        -0.813  -0.775  -0.725  -0.976  -0.917  -0.824  -0.903  -0.860  -0.767
61    P        -1.203  -1.228  -1.132  -1.274  -1.324  -1.172  -1.095  -1.112  -0.969
62    N         0.543   0.495   0.511   0.520   0.436   0.420   0.347   0.252   0.224
63    L        -1.104  -1.161  -1.106  -1.259  -1.323  -1.177  -1.003  -1.051  -0.946
64    K        -0.361  -0.373  -0.589  -0.266  -0.297  -0.599  -0.328  -0.342  -0.602
65    V         0.368   0.360   0.460   0.175   0.144   0.293   0.009  -0.012   0.120
66    F         0.237   0.149  -0.040   0.399   0.280  -0.070   0.234   0.109  -0.179
67    F         0.543   0.571   0.522   0.557   0.607   0.483   0.347   0.394   0.247
68    F         0.871   0.836   0.675   1.043   1.008   0.768   0.909   0.853   0.543
69    D         1.537   1.549   1.659   1.422   1.442   1.617   1.696   1.714   1.896
70    I         0.871   0.820   0.677   0.890   0.821   0.571   0.909   0.826   0.547
71    D         1.537   1.549   1.659   1.422   1.442   1.617   1.696   1.714   1.896
72    N         1.537   1.549   1.659   1.605   1.623   1.797   1.696   1.714   1.896
73    C         0.871   0.836   0.675   1.185   1.145   0.911   0.909   0.853   0.543
74    L         1.537   1.549   1.659   1.304   1.324   1.500   1.696   1.714   1.896
75    Y         1.537   1.549   1.659   1.588   1.597   1.780   1.696   1.714   1.896
76    K        -0.607  -0.593  -0.639  -0.536  -0.484  -0.577  -0.665  -0.634  -0.668
77    S        -0.301  -0.259  -0.204  -0.457  -0.401  -0.308  -0.553  -0.492  -0.425
78    S         0.871   0.836   0.675   1.032   0.992   0.725   0.909   0.853   0.543
79    T        -0.914  -0.962  -1.043  -0.742  -0.826  -1.017  -0.778  -0.829  -0.882
80    R        -0.054  -0.115  -0.151   0.005  -0.105  -0.173  -0.216  -0.304  -0.354
81    I         0.543   0.522   0.513   0.457   0.418   0.377   0.347   0.303   0.228
82    H         0.237   0.197  -0.030   0.492   0.433   0.073   0.234   0.178  -0.165
83    D        -0.361  -0.446  -0.583  -0.329  -0.447  -0.656  -0.328  -0.434  -0.595
84    L         0.368   0.360   0.460   0.044   0.036   0.211   0.009  -0.012   0.120
85    M         1.537   1.549   1.659   1.772   1.787   1.962   1.696   1.714   1.896
86    Q        -0.607  -0.629  -0.666  -0.436  -0.481  -0.541  -0.665  -0.697  -0.703
87    Q        -1.526  -1.546  -1.451  -1.398  -1.438  -1.313  -1.228  -1.237  -1.093
88    S        -1.220  -1.200  -1.125  -1.281  -1.258  -1.143  -1.115  -1.093  -0.964
89    I         1.537   1.549   1.659   1.525   1.544   1.718   1.696   1.714   1.896
90    L        -1.411  -1.414  -1.414  -1.225  -1.230  -1.297  -1.115  -1.116  -1.062
91    R        -1.526  -1.519  -1.432  -1.379  -1.383  -1.254  -1.228  -1.218  -1.079
92    F         0.543   0.552   0.521   0.527   0.534   0.462   0.347   0.359   0.245
93    F         1.537   1.549   1.659   1.635   1.662   1.827   1.696   1.714   1.896
94    Q        -1.104  -1.121  -1.098  -0.975  -1.004  -0.966  -1.003  -1.015  -0.938
95    T        -1.220  -1.203  -1.113  -1.263  -1.257  -1.075  -1.115  -1.097  -0.955
96    H        -1.104  -1.072  -1.073  -1.011  -0.978  -0.929  -1.003  -0.964  -0.917
97    L         0.871   0.918   0.686   0.717   0.781   0.479   0.909   0.982   0.564
98    K        -1.104  -1.058  -1.075  -0.958  -0.885  -0.906  -1.003  -0.954  -0.919
99    L         0.871   0.820   0.677   0.700   0.636   0.427   0.909   0.826   0.547
100   S        -0.798  -0.769  -0.721  -0.935  -0.894  -0.787  -0.890  -0.865  -0.764
101   P        -1.526  -1.507  -1.443  -1.468  -1.446  -1.285  -1.228  -1.209  -1.087
102   E         0.871   0.912   0.687   0.969   1.034   0.717   0.909   0.973   0.566
103   D        -0.607  -0.623  -0.656  -0.657  -0.680  -0.698  -0.665  -0.683  -0.691
104   A         1.537   1.549   1.659   1.590   1.603   1.783   1.696   1.714   1.896
105   H        -1.104  -1.114  -1.088  -0.924  -0.945  -0.893  -1.003  -1.010  -0.931
106   V        -0.798  -0.769  -0.721  -0.835  -0.797  -0.702  -0.890  -0.865  -0.764
107   L         1.537   1.549   1.659   1.304   1.324   1.500   1.696   1.714   1.896
108   N        -0.301  -0.266  -0.225  -0.295  -0.243  -0.197  -0.553  -0.503  -0.455
109   N        -1.833  -1.813  -1.714  -1.661  -1.630  -1.487  -1.340  -1.321  -1.176
110   S        -1.411  -1.414  -1.414  -1.145  -1.155  -1.151  -1.115  -1.116  -1.062
111   Y         1.537   1.549   1.659   1.588   1.597   1.780   1.696   1.714   1.896
112   Y         1.537   1.549   1.659   1.588   1.597   1.780   1.696   1.714   1.896
113   K        -0.054  -0.067  -0.144  -0.089  -0.118  -0.196  -0.216  -0.235  -0.347
114   E        -1.104  -1.117  -1.091  -0.931  -0.942  -0.889  -1.003  -1.010  -0.933
115   Y         1.537   1.549   1.659   1.588   1.597   1.780   1.696   1.714   1.896
116   G         1.537   1.549   1.659   1.645   1.663   1.837   1.696   1.714   1.896
117   L         0.543   0.495   0.511   0.214   0.132   0.134   0.347   0.252   0.224
118   A         1.537   1.549   1.659   1.590   1.603   1.783   1.696   1.714   1.896
119   I         0.871   0.836   0.675   0.890   0.845   0.567   0.909   0.853   0.543
120   R        -0.682  -0.679  -0.683  -0.739  -0.734  -0.749  -0.778  -0.771  -0.725
121   G         1.537   1.549   1.659   1.645   1.663   1.837   1.696   1.714   1.896
122   L         1.537   1.549   1.659   1.304   1.324   1.500   1.696   1.714   1.896
123   V         0.237   0.233  -0.031   0.393   0.373  -0.037   0.234   0.228  -0.166
124   M        -0.607  -0.538  -0.655  -0.609  -0.527  -0.714  -0.665  -0.591  -0.690
125   F        -0.054   0.005  -0.119   0.071   0.145  -0.029  -0.216  -0.141  -0.303
126   H         0.871   0.912   0.687   1.099   1.149   0.842   0.909   0.973   0.566
127   K        -1.104  -1.071  -1.067  -0.995  -0.940  -0.931  -1.003  -0.971  -0.912
128   V         0.368   0.392   0.470   0.146   0.185   0.297   0.009   0.053   0.141
129   N         0.871   0.947   0.690   0.830   0.929   0.589   0.909   1.026   0.571
130   A        -0.054  -0.074  -0.141  -0.026  -0.050  -0.170  -0.216  -0.235  -0.340
131   L        -0.798  -0.815  -0.714  -1.020  -1.049  -0.871  -0.890  -0.902  -0.759
132   E         0.368   0.366   0.459   0.079   0.079   0.188   0.009   0.001   0.119
133   Y         1.537   1.549   1.659   1.588   1.597   1.780   1.696   1.714   1.896
134   N         0.871   0.820   0.677   0.988   0.919   0.686   0.909   0.826   0.547
135   R        -1.526  -1.520  -1.431  -1.289  -1.276  -1.137  -1.228  -1.218  -1.078
136   L        -0.607  -0.649  -0.677  -0.855  -0.917  -0.919  -0.665  -0.711  -0.716
137   V         1.537   1.549   1.659   1.608   1.617   1.800   1.696   1.714   1.896
138   D         1.537   1.549   1.659   1.422   1.442   1.617   1.696   1.714   1.896
139   D         0.871   0.820   0.677   0.848   0.789   0.608   0.909   0.826   0.547
140   S         0.368   0.380   0.461   0.246   0.268   0.368   0.009   0.029   0.121
141   L         1.537   1.549   1.659   1.304   1.324   1.500   1.696   1.714   1.896
142   P         0.543   0.548   0.547   0.524   0.541   0.475   0.347   0.353   0.296
143   L         1.537   1.549   1.659   1.304   1.324   1.500   1.696   1.714   1.896
144   Q        -1.104  -1.144  -1.099  -1.023  -1.101  -1.041  -1.003  -1.038  -0.941
145   D        -1.220  -1.200  -1.125  -1.310  -1.282  -1.141  -1.115  -1.093  -0.964
146   I         0.368   0.360   0.460   0.146   0.123   0.278   0.009  -0.012   0.120
147   L         0.543   0.513   0.514   0.214   0.163   0.138   0.347   0.286   0.229
148   K         0.871   0.873   0.686   0.894   0.890   0.655   0.909   0.912   0.564
149   P        -0.607  -0.676  -0.670  -0.511  -0.613  -0.615  -0.665  -0.739  -0.704
150   D        -0.054  -0.039  -0.130  -0.179  -0.150  -0.279  -0.216  -0.189  -0.325
151   I        -1.833  -1.781  -1.715  -1.860  -1.749  -1.705  -1.340  -1.296  -1.176
152   P        -1.526  -1.534  -1.432  -1.505  -1.514  -1.368  -1.228  -1.229  -1.079
153   L         0.871   0.918   0.686   0.730   0.792   0.508   0.909   0.982   0.564
154   R         0.871   0.871   0.678   1.059   1.056   0.766   0.909   0.909   0.549
155   N        -0.798  -0.758  -0.712  -0.872  -0.812  -0.733  -0.890  -0.852  -0.756
156   M        -0.798  -0.767  -0.718  -0.849  -0.804  -0.753  -0.890  -0.857  -0.763
157   L         0.871   0.836   0.675   0.717   0.679   0.461   0.909   0.853   0.543
158   L        -0.798  -0.792  -0.714  -0.937  -0.924  -0.822  -0.890  -0.880  -0.758
159   R        -0.914  -0.962  -1.058  -0.654  -0.735  -0.917  -0.778  -0.828  -0.897
160   L         0.312   0.321   0.447  -0.179  -0.165   0.038  -0.103  -0.090   0.093
161   R        -0.301  -0.314  -0.229  -0.472  -0.514  -0.415  -0.553  -0.573  -0.462
162   Q        -0.503  -0.548  -0.642  -0.355  -0.426  -0.571  -0.507  -0.567  -0.667
163   S        -0.251  -0.250  -0.203  -0.250  -0.257  -0.162  -0.503  -0.511  -0.431
164   G        -0.143  -0.151  -0.196  -0.093  -0.108  -0.221  -0.319  -0.331  -0.412
165   K        -0.361  -0.330  -0.569  -0.252  -0.221  -0.545  -0.328  -0.288  -0.577
166   I        -0.798  -0.808  -0.725  -0.916  -0.930  -0.807  -0.890  -0.894  -0.769
167   D        -0.361  -0.448  -0.603  -0.311  -0.432  -0.652  -0.328  -0.436  -0.619
168   K         0.543   0.548   0.547   0.404   0.399   0.387   0.347   0.353   0.296
169   L        -0.607  -0.620  -0.664  -0.711  -0.719  -0.708  -0.665  -0.679  -0.697
170   W         1.537   1.549   1.659   1.832   1.848   2.021   1.696   1.714   1.896
171   L         0.871   0.820   0.677   0.700   0.636   0.427   0.909   0.826   0.547
172   F         0.543   0.548   0.547   0.564   0.576   0.539   0.347   0.353   0.296
173   T         1.537   1.549   1.659   1.652   1.669   1.844   1.696   1.714   1.896
174   N         1.537   1.549   1.659   1.605   1.623   1.797   1.696   1.714   1.896
175   A         1.537   1.549   1.659   1.590   1.603   1.783   1.696   1.714   1.896
176   Y         1.537   1.549   1.659   1.588   1.597   1.780   1.696   1.714   1.896
177   K         0.543   0.513   0.514   0.383   0.320   0.293   0.347   0.286   0.229
178   N         0.237   0.149  -0.040   0.439   0.320   0.042   0.234   0.109  -0.179
179   H         1.537   1.549   1.659   1.692   1.705   1.883   1.696   1.714   1.896
180   A         0.543   0.547   0.520   0.532   0.532   0.466   0.347   0.350   0.242
181   I        -0.914  -0.942  -1.044  -1.040  -1.079  -1.240  -0.778  -0.809  -0.882
182   R         1.537   1.549   1.659   1.670   1.683   1.861   1.696   1.714   1.896
183   C         0.368   0.416   0.483   0.305   0.377   0.482   0.009   0.100   0.167
184   L        -0.798  -0.817  -0.719  -1.031  -1.068  -0.918  -0.890  -0.905  -0.762
185   R        -0.376  -0.364  -0.241  -0.555  -0.554  -0.353  -0.665  -0.647  -0.480
186   L        -0.054  -0.100  -0.140  -0.293  -0.350  -0.399  -0.216  -0.274  -0.334
187   L         0.871   0.836   0.675   0.712   0.671   0.452   0.909   0.853   0.543
188   G         0.871   0.871   0.678   1.046   1.051   0.768   0.909   0.909   0.549
189   I         0.237   0.205  -0.030   0.302   0.260  -0.128   0.234   0.189  -0.164
190   A        -0.798  -0.828  -0.730  -0.894  -0.943  -0.806  -0.890  -0.918  -0.774
191   D         1.537   1.549   1.659   1.422   1.442   1.617   1.696   1.714   1.896
192   L        -0.361  -0.411  -0.591  -0.410  -0.468  -0.706  -0.328  -0.390  -0.604
193   F         0.871   0.836   0.675   1.032   0.997   0.742   0.909   0.853   0.543
194   D         0.871   0.871   0.678   0.824   0.830   0.555   0.909   0.909   0.549
195   G         1.537   1.549   1.659   1.645   1.663   1.837   1.696   1.714   1.896
196   L         0.312   0.321   0.447  -0.179  -0.163   0.036  -0.103  -0.090   0.093
197   T         1.537   1.549   1.659   1.652   1.669   1.844   1.696   1.714   1.896
198   Y         0.871   0.882   0.687   1.000   1.009   0.752   0.909   0.926   0.566
199   C         1.537   1.549   1.659   1.772   1.791   1.962   1.696   1.714   1.896
200   D         1.537   1.549   1.659   1.422   1.442   1.617   1.696   1.714   1.896
201   Y         1.537   1.549   1.659   1.588   1.597   1.780   1.696   1.714   1.896
202   S        -0.607  -0.642  -0.652  -0.501  -0.556  -0.574  -0.665  -0.705  -0.687
203   R        -1.526  -1.519  -1.432  -1.254  -1.258  -1.121  -1.228  -1.218  -1.079
204   T        -1.411  -1.405  -1.405  -1.223  -1.231  -1.259  -1.115  -1.107  -1.055
205   D        -0.185  -0.149  -0.170  -0.342  -0.273  -0.307  -0.441  -0.394  -0.390
206   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
207   L         0.543   0.548   0.547   0.214   0.224   0.199   0.347   0.353   0.296
208   V        -0.607  -0.593  -0.639  -0.652  -0.618  -0.708  -0.665  -0.634  -0.668
209   C         0.871   0.820   0.677   1.177   1.113   0.896   0.909   0.826   0.547
210   K         1.537   1.549   1.659   1.476   1.486   1.670   1.696   1.714   1.896
211   P         1.537   1.549   1.659   1.655   1.683   1.846   1.696   1.714   1.896
212   H        -0.798  -0.788  -0.723  -0.785  -0.758  -0.687  -0.890  -0.869  -0.766
213   V        -0.607  -0.567  -0.630  -0.498  -0.416  -0.532  -0.665  -0.605  -0.658
214   K        -1.104  -1.021  -1.060  -1.159  -1.030  -1.088  -1.003  -0.921  -0.906
215   A        -0.301  -0.320  -0.232  -0.344  -0.382  -0.237  -0.553  -0.581  -0.466
216   F         0.871   0.820   0.677   1.040   0.983   0.766   0.909   0.826   0.547
217   E        -0.054  -0.058  -0.137  -0.089  -0.088  -0.236  -0.216  -0.220  -0.330
218   K         0.237   0.182  -0.027   0.314   0.234  -0.049   0.234   0.156  -0.160
219   A        -0.054  -0.100  -0.140   0.034  -0.032  -0.083  -0.216  -0.274  -0.334
220   M        -0.301  -0.270  -0.211  -0.294  -0.238  -0.189  -0.553  -0.509  -0.435
221   K        -1.104  -1.078  -1.081  -1.109  -1.063  -1.105  -1.003  -0.973  -0.924
222   E        -0.301  -0.300  -0.223  -0.509  -0.498  -0.400  -0.553  -0.551  -0.453
223   S        -0.376  -0.364  -0.241  -0.493  -0.477  -0.287  -0.665  -0.647  -0.480
224   G        -0.054  -0.058  -0.137   0.033   0.027  -0.117  -0.216  -0.220  -0.330
225   L         0.312   0.325   0.449  -0.115  -0.082   0.115  -0.103  -0.081   0.097
226   A        -1.220  -1.188  -1.124  -1.237  -1.196  -1.067  -1.115  -1.085  -0.964
227   R        -0.607  -0.528  -0.648  -0.703  -0.601  -0.736  -0.665  -0.577  -0.678
228   Y        -1.526  -1.510  -1.438  -1.398  -1.390  -1.239  -1.228  -1.208  -1.083
229   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
230   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
231   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
232   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
233   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
234   E        -0.914  -0.888  -1.033  -0.711  -0.673  -0.948  -0.778  -0.750  -0.872
235   N        -1.104  -1.124  -1.097  -1.138  -1.193  -1.152  -1.003  -1.022  -0.939
236   A        -0.376  -0.364  -0.241  -0.381  -0.351  -0.167  -0.665  -0.647  -0.480
237   Y         0.237   0.149  -0.040   0.439   0.315   0.060   0.234   0.109  -0.179
238   F         0.871   0.912   0.687   1.040   1.102   0.783   0.909   0.973   0.566
239   I         0.368   0.403   0.473   0.175   0.236   0.323   0.009   0.075   0.147
240   D         1.537   1.549   1.659   1.422   1.442   1.617   1.696   1.714   1.896
241   D         1.537   1.549   1.659   1.422   1.442   1.617   1.696   1.714   1.896
242   S         1.537   1.549   1.659   1.650   1.673   1.841   1.696   1.714   1.896
243   G        -0.798  -0.828  -0.730  -0.839  -0.890  -0.735  -0.890  -0.918  -0.774
244   K        -0.607  -0.571  -0.654  -0.808  -0.747  -0.849  -0.665  -0.616  -0.687
245   N         1.537   1.549   1.659   1.605   1.623   1.797   1.696   1.714   1.896
246   I        -0.054  -0.058  -0.137  -0.058  -0.064  -0.152  -0.216  -0.220  -0.330
247   E        -0.361  -0.319  -0.576  -0.319  -0.279  -0.672  -0.328  -0.277  -0.586
248   T        -1.104  -1.148  -1.094  -1.005  -1.078  -1.004  -1.003  -1.041  -0.937
249   G        -0.301  -0.260  -0.224  -0.372  -0.309  -0.263  -0.553  -0.494  -0.454
250   I        -1.526  -1.530  -1.432  -1.519  -1.519  -1.361  -1.228  -1.224  -1.079
251   K        -0.607  -0.608  -0.656  -0.645  -0.660  -0.691  -0.665  -0.673  -0.691
252   L         0.543   0.495   0.511   0.253   0.179   0.194   0.347   0.252   0.224
253   G         0.871   0.882   0.687   1.065   1.081   0.824   0.909   0.926   0.566
254   M        -1.104  -1.036  -1.077  -0.945  -0.833  -0.918  -1.003  -0.932  -0.921
255   K        -1.526  -1.515  -1.442  -1.382  -1.376  -1.239  -1.228  -1.214  -1.086
256   T        -1.553  -1.566  -1.454  -1.468  -1.501  -1.303  -1.242  -1.249  -1.094
257   C        -1.220  -1.212  -1.127  -1.041  -1.041  -0.891  -1.115  -1.103  -0.966
258   I        -0.185  -0.223  -0.177  -0.338  -0.390  -0.297  -0.441  -0.482  -0.401
259   H         0.237   0.149  -0.040   0.533   0.411   0.137   0.234   0.109  -0.179
260   L         0.237   0.239  -0.046   0.132   0.139  -0.257   0.234   0.238  -0.189
261   V         0.237   0.205  -0.030   0.434   0.386   0.048   0.234   0.189  -0.164
262   E         0.871   0.836   0.675   0.966   0.934   0.691   0.909   0.853   0.543
263   N        -1.833  -1.818  -1.732  -1.865  -1.824  -1.667  -1.340  -1.325  -1.188
264   E        -0.914  -0.842  -1.021  -0.715  -0.603  -0.927  -0.778  -0.696  -0.859
265   V        -1.104  -1.123  -1.084  -1.034  -1.081  -1.007  -1.003  -1.020  -0.928
266   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
267   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
268   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
269   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
270   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
271   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
272   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
273   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
274   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
275   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
276   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
277   N        -1.630  -1.610  -1.474  -1.741  -1.668  -1.506  -1.303  -1.282  -1.109
278   E         0.412   0.451   0.489   0.196   0.272   0.282   0.097   0.168   0.180
279   I        -1.526  -1.533  -1.432  -1.379  -1.381  -1.223  -1.228  -1.228  -1.079
280   L        -0.798  -0.783  -0.722  -1.039  -1.013  -0.882  -0.890  -0.876  -0.765
281   G        -0.607  -0.629  -0.666  -0.470  -0.508  -0.554  -0.665  -0.697  -0.703
282   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
283   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
284   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
285   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
286   Q        -1.220  -1.232  -1.117  -1.130  -1.145  -0.959  -1.115  -1.119  -0.958
287   T        -0.607  -0.620  -0.664  -0.550  -0.569  -0.629  -0.665  -0.679  -0.697
288   P         0.237   0.190  -0.028   0.506   0.458   0.142   0.234   0.167  -0.162
289   E        -0.853  -0.833  -0.739  -0.931  -0.894  -0.750  -0.948  -0.923  -0.784
290   G        -0.607  -0.584  -0.661  -0.555  -0.523  -0.636  -0.665  -0.638  -0.693
291   A        -1.220  -1.230  -1.125  -1.245  -1.258  -1.093  -1.115  -1.116  -0.965
292   I        -1.833  -1.854  -1.727  -1.568  -1.602  -1.393  -1.340  -1.350  -1.184
293   V        -0.682  -0.706  -0.684  -0.717  -0.747  -0.679  -0.778  -0.796  -0.727
294   I         0.871   0.873   0.686   0.890   0.896   0.588   0.909   0.912   0.564
295   S        -0.798  -0.793  -0.719  -0.832  -0.819  -0.703  -0.890  -0.881  -0.763
296   D        -0.914  -0.926  -1.024  -0.857  -0.876  -1.011  -0.778  -0.789  -0.863
297   I         0.871   0.871   0.678   0.890   0.894   0.573   0.909   0.909   0.549
298   L        -1.220  -1.247  -1.117  -1.240  -1.255  -1.070  -1.115  -1.130  -0.958
299   E        -0.607  -0.630  -0.651  -0.751  -0.775  -0.812  -0.665  -0.682  -0.686
300   L         0.871   0.820   0.677   0.717   0.658   0.465   0.909   0.826   0.547
301   P        -0.914  -0.935  -1.030  -0.690  -0.719  -0.912  -0.778  -0.799  -0.868
302   H        -0.607  -0.614  -0.651  -0.599  -0.616  -0.635  -0.665  -0.669  -0.686
303   V        -0.376  -0.381  -0.257  -0.676  -0.706  -0.521  -0.665  -0.670  -0.501
304   V        -1.526  -1.500  -1.428  -1.439  -1.410  -1.261  -1.228  -1.203  -1.076
305   S         0.003  -0.002  -0.119   0.114   0.103  -0.117  -0.103  -0.113  -0.297
306   D         0.412   0.431   0.481   0.158   0.200   0.225   0.097   0.129   0.163
307   L         0.412   0.405   0.468  -0.013  -0.033   0.062   0.097   0.078   0.137
308   F         1.537   1.549   1.659   1.653   1.671   1.845   1.696   1.714   1.896
309   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
310   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
311   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
312   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
313   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
314   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
315   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
316   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
317   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
318   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
319   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
320   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
321   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
322   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
323   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
324   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
325   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
326   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
327   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
328   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
329   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
330   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
331   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
332   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
333   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
334   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
335   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
336   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
337   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
338   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
339   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
340   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
341   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
342   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
343   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
344   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
345   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
346   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
347   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
348   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
349   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
350   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
351   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
352   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
353   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
354   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
355   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
356   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
357   -        -1.222  -1.218  -1.124  -1.253  -1.244  -1.083  -1.103  -1.096  -0.961
358   -        -1.630  -1.618  -1.474  -1.531  -1.489  -1.299  -1.303  -1.288  -1.109
359   -        -0.659  -0.683  -0.670  -0.594  -0.633  -0.612  -0.703  -0.732  -0.700
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P53078
Output conservation file - output/P53078
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
