1     M         1.055   1.071   1.116   1.191   1.214   1.271   1.110   1.133   1.194
2     S        -0.282  -0.486  -0.620  -0.116  -0.390  -0.622  -0.279  -0.552  -0.740
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     A        -0.582  -0.535  -0.618  -0.605  -0.492  -0.657  -0.706  -0.618  -0.737
9     V        -1.976  -2.022  -1.862  -1.716  -1.827  -1.591  -1.560  -1.577  -1.373
10    F        -0.771  -0.761  -0.682  -1.039  -0.982  -0.891  -0.983  -0.940  -0.824
11    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    N        -1.042  -1.043  -1.151  -0.795  -0.798  -1.057  -0.983  -0.982  -1.078
13    A        -1.266  -1.203  -1.168  -1.386  -1.310  -1.209  -1.262  -1.184  -1.096
14    T        -0.682  -0.706  -0.680  -0.633  -0.665  -0.650  -0.843  -0.858  -0.820
15    L        -1.762  -1.727  -1.560  -1.827  -1.720  -1.475  -1.541  -1.484  -1.271
16    S        -0.582  -0.439  -0.639  -0.605  -0.427  -0.709  -0.706  -0.541  -0.770
17    G        -1.661  -1.548  -1.519  -1.482  -1.343  -1.279  -1.453  -1.342  -1.239
18    L        -0.835  -0.820  -0.701  -1.209  -1.167  -0.966  -1.026  -1.009  -0.847
19    V        -1.227  -1.265  -1.159  -1.221  -1.251  -1.091  -1.240  -1.240  -1.087
20    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
21    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
22    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
23    Q        -2.095  -2.053  -1.863  -1.732  -1.704  -1.444  -1.667  -1.604  -1.374
24    A        -1.150  -1.104  -1.138  -1.168  -1.122  -1.113  -1.133  -1.088  -1.068
25    S        -1.661  -1.494  -1.527  -1.566  -1.340  -1.423  -1.453  -1.293  -1.245
26    T        -0.582  -0.650  -0.659  -0.515  -0.605  -0.655  -0.706  -0.781  -0.796
27    Y        -0.148  -0.129  -0.032  -0.419  -0.392  -0.256  -0.492  -0.473  -0.337
28    S        -1.780  -1.761  -1.544  -1.783  -1.728  -1.422  -1.560  -1.508  -1.260
29    Q        -1.976  -1.981  -1.847  -1.648  -1.713  -1.536  -1.560  -1.550  -1.363
30    T        -0.716  -0.746  -0.665  -0.778  -0.803  -0.680  -0.919  -0.923  -0.805
31    L        -0.716  -0.768  -0.680  -0.987  -1.008  -0.834  -0.919  -0.956  -0.823
32    Q        -1.661  -1.561  -1.516  -1.492  -1.357  -1.291  -1.453  -1.347  -1.237
33    N        -0.897  -1.115  -1.143  -0.526  -0.834  -0.934  -0.813  -1.061  -1.070
34    V        -1.465  -1.356  -1.185  -1.773  -1.628  -1.339  -1.453  -1.328  -1.112
35    A        -1.780  -1.593  -1.541  -1.722  -1.494  -1.384  -1.560  -1.392  -1.257
36    H        -1.661  -1.494  -1.527  -1.450  -1.226  -1.280  -1.453  -1.293  -1.245
37    Y        -2.410  -2.272  -2.110  -2.318  -2.097  -1.920  -1.774  -1.651  -1.442
38    Q        -1.346  -1.338  -1.178  -1.246  -1.243  -1.008  -1.347  -1.313  -1.106
39    P        -0.522  -0.638  -0.664  -0.454  -0.655  -0.741  -0.599  -0.759  -0.798
40    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
41    Q        -1.465  -1.504  -1.527  -1.135  -1.208  -1.304  -1.240  -1.274  -1.244
42    L         1.055   1.071   1.116   0.831   0.866   0.953   1.110   1.133   1.194
43    N         0.370   0.281   0.086   0.606   0.499   0.165   0.362   0.226  -0.124
44    F        -1.465  -1.480  -1.525  -1.364  -1.390  -1.440  -1.240  -1.248  -1.242
45    M        -1.150  -1.196  -1.157  -0.990  -1.096  -1.064  -1.133  -1.185  -1.087
46    E         1.055   1.071   1.116   1.095   1.123   1.186   1.110   1.133   1.194
47    K        -0.716  -0.712  -0.665  -0.720  -0.692  -0.603  -0.919  -0.893  -0.805
48    Y        -0.716  -0.637  -0.648  -1.011  -0.857  -0.844  -0.919  -0.777  -0.779
49    W         1.055   1.071   1.116   1.118   1.136   1.206   1.110   1.133   1.194
50    A        -0.582  -0.625  -0.646  -0.715  -0.787  -0.837  -0.706  -0.744  -0.776
51    A        -0.148  -0.109  -0.027  -0.444  -0.386  -0.244  -0.492  -0.435  -0.327
52    W        -0.205  -0.149  -0.034  -0.416  -0.324  -0.142  -0.599  -0.509  -0.339
53    Y         0.370   0.320   0.087   0.437   0.381  -0.007   0.362   0.284  -0.122
54    S        -2.410  -2.285  -2.121  -2.161  -2.046  -1.775  -1.774  -1.663  -1.449
55    Y        -0.148  -0.160  -0.038  -0.315  -0.342  -0.145  -0.492  -0.530  -0.347
56    M        -0.282  -0.453  -0.619  -0.003  -0.249  -0.560  -0.279  -0.508  -0.739
57    N        -1.661  -1.698  -1.547  -1.412  -1.468  -1.287  -1.453  -1.462  -1.261
58    N         1.055   1.071   1.116   1.202   1.230   1.280   1.110   1.133   1.194
59    D         1.055   1.071   1.116   1.155   1.171   1.239   1.110   1.133   1.194
60    V        -0.716  -0.584  -0.665  -0.950  -0.773  -0.833  -0.919  -0.769  -0.804
61    L        -1.150  -1.221  -1.158  -1.371  -1.445  -1.328  -1.133  -1.186  -1.086
62    A         1.055   1.071   1.116   0.939   0.958   1.049   1.110   1.133   1.194
63    T         0.370   0.320   0.087   0.545   0.489   0.165   0.362   0.284  -0.122
64    G         1.055   1.071   1.116   1.093   1.118   1.184   1.110   1.133   1.194
65    L         0.370   0.320   0.087   0.234   0.183  -0.144   0.362   0.284  -0.122
66    M        -0.582  -0.562  -0.645  -0.554  -0.506  -0.730  -0.706  -0.664  -0.775
67    F        -0.582  -0.697  -0.676  -0.706  -0.878  -0.828  -0.706  -0.869  -0.818
68    F         1.055   1.071   1.116   0.920   0.958   1.032   1.110   1.133   1.194
69    L        -0.282  -0.317  -0.595  -0.364  -0.409  -0.801  -0.279  -0.330  -0.706
70    L        -0.282  -0.311  -0.597  -0.317  -0.341  -0.699  -0.279  -0.323  -0.709
71    H         1.055   1.071   1.116   1.033   1.057   1.131   1.110   1.133   1.194
72    E         1.055   1.071   1.116   1.095   1.123   1.186   1.110   1.133   1.194
73    F        -1.227  -1.196  -1.144  -1.440  -1.369  -1.302  -1.240  -1.177  -1.072
74    M        -1.465  -1.597  -1.533  -1.201  -1.449  -1.444  -1.240  -1.362  -1.249
75    Y         1.055   1.071   1.116   1.051   1.082   1.148   1.110   1.133   1.194
76    F         1.055   1.071   1.116   0.920   0.958   1.032   1.110   1.133   1.194
77    F        -0.148   0.018   0.022  -0.382  -0.061  -0.101  -0.492  -0.208  -0.237
78    R         1.055   1.071   1.116   1.185   1.203   1.266   1.110   1.133   1.194
79    C         0.370   0.281   0.086   0.660   0.544   0.210   0.362   0.226  -0.124
80    L        -0.582  -0.653  -0.661  -0.790  -0.892  -0.865  -0.706  -0.801  -0.799
81    P         1.055   1.071   1.116   1.099   1.122   1.190   1.110   1.133   1.194
82    W         1.055   1.071   1.116   1.118   1.136   1.206   1.110   1.133   1.194
83    F        -0.835  -0.604  -0.657  -0.950  -0.535  -0.708  -1.026  -0.713  -0.790
84    I         1.055   1.071   1.116   1.045   1.064   1.142   1.110   1.133   1.194
85    I         0.370   0.320   0.087   0.419   0.348  -0.045   0.362   0.284  -0.122
86    D         1.055   1.071   1.116   1.155   1.171   1.239   1.110   1.133   1.194
87    Q        -0.835  -0.826  -0.700  -0.856  -0.900  -0.709  -1.026  -1.018  -0.846
88    I        -0.282  -0.486  -0.620  -0.150  -0.439  -0.677  -0.279  -0.552  -0.740
89    P         1.055   1.071   1.116   1.099   1.122   1.190   1.110   1.133   1.194
90    Y         0.370   0.281   0.086   0.476   0.377   0.091   0.362   0.226  -0.124
91    F         1.055   1.071   1.116   0.920   0.958   1.032   1.110   1.133   1.194
92    R        -0.582  -0.636  -0.659  -0.405  -0.491  -0.555  -0.706  -0.775  -0.797
93    R        -0.148  -0.095  -0.021  -0.264  -0.178  -0.072  -0.492  -0.409  -0.316
94    W         0.033   0.020  -0.008   0.037   0.004  -0.081  -0.172  -0.205  -0.292
95    K         1.055   1.071   1.116   1.068   1.097   1.162   1.110   1.133   1.194
96    L         0.033   0.223   0.067  -0.103   0.205  -0.084  -0.172   0.134  -0.157
97    Q         1.055   1.071   1.116   1.171   1.194   1.253   1.110   1.133   1.194
98    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
99    P        -1.150  -1.196  -1.155  -1.007  -1.066  -1.023  -1.133  -1.160  -1.083
100   T        -1.346  -1.365  -1.176  -1.400  -1.433  -1.157  -1.347  -1.338  -1.105
101   K         1.055   1.071   1.116   1.068   1.097   1.162   1.110   1.133   1.194
102   I        -0.582  -0.714  -0.677  -0.554  -0.765  -0.684  -0.706  -0.884  -0.818
103   P         1.055   1.071   1.116   1.099   1.122   1.190   1.110   1.133   1.194
104   S         0.033  -0.068  -0.021   0.000  -0.172  -0.118  -0.172  -0.360  -0.316
105   A        -2.410  -2.337  -2.122  -2.211  -2.151  -1.791  -1.774  -1.692  -1.449
106   K        -0.582  -0.714  -0.677  -0.583  -0.812  -0.744  -0.706  -0.884  -0.818
107   E         1.055   1.071   1.116   1.095   1.123   1.186   1.110   1.133   1.194
108   Q         1.055   1.071   1.116   1.171   1.194   1.253   1.110   1.133   1.194
109   L        -0.716  -0.667  -0.654  -0.940  -0.783  -0.809  -0.919  -0.812  -0.787
110   Y        -0.582  -0.302  -0.606  -0.566  -0.144  -0.633  -0.706  -0.326  -0.722
111   C         1.055   1.071   1.116   1.256   1.276   1.328   1.110   1.133   1.194
112   L        -0.897  -1.115  -1.143  -0.906  -1.205  -1.214  -0.813  -1.061  -1.070
113   K        -0.282  -0.486  -0.620  -0.086  -0.351  -0.564  -0.279  -0.552  -0.740
114   S        -0.582  -0.541  -0.659  -0.679  -0.706  -0.869  -0.706  -0.707  -0.797
115   V         1.055   1.071   1.116   1.076   1.096   1.170   1.110   1.133   1.194
116   L         1.055   1.071   1.116   0.831   0.866   0.953   1.110   1.133   1.194
117   L        -0.582  -0.562  -0.645  -0.770  -0.722  -0.823  -0.706  -0.664  -0.775
118   S         1.055   1.071   1.116   1.060   1.089   1.155   1.110   1.133   1.194
119   H         1.055   1.071   1.116   1.033   1.057   1.131   1.110   1.133   1.194
120   F         0.370   0.281   0.086   0.355   0.267   0.009   0.362   0.226  -0.124
121   L        -0.582  -0.697  -0.676  -0.740  -0.890  -0.796  -0.706  -0.869  -0.818
122   V         1.055   1.071   1.116   1.076   1.096   1.170   1.110   1.133   1.194
123   E         1.055   1.071   1.116   1.095   1.123   1.186   1.110   1.133   1.194
124   A         0.033  -0.068  -0.021  -0.208  -0.421  -0.361  -0.172  -0.360  -0.316
125   I        -0.835  -0.826  -0.700  -1.009  -1.001  -0.818  -1.026  -1.018  -0.846
126   P         0.033  -0.068  -0.021   0.057  -0.114  -0.057  -0.172  -0.360  -0.316
127   I         1.055   1.071   1.116   1.045   1.064   1.142   1.110   1.133   1.194
128   W         1.055   1.071   1.116   1.118   1.136   1.206   1.110   1.133   1.194
129   T        -1.346  -1.320  -1.177  -1.538  -1.535  -1.302  -1.347  -1.297  -1.106
130   F         1.055   1.071   1.116   0.920   0.958   1.032   1.110   1.133   1.194
131   H        -0.282  -0.453  -0.619  -0.133  -0.359  -0.617  -0.279  -0.508  -0.739
132   P         1.055   1.071   1.116   1.099   1.122   1.190   1.110   1.133   1.194
133   M        -1.150  -1.196  -1.155  -1.074  -1.133  -1.125  -1.133  -1.160  -1.083
134   C         0.370   0.281   0.086   0.644   0.520   0.168   0.362   0.226  -0.124
135   E        -1.661  -1.707  -1.541  -1.473  -1.552  -1.339  -1.453  -1.460  -1.256
136   K        -1.150  -1.215  -1.157  -1.054  -1.162  -1.053  -1.133  -1.202  -1.087
137   L        -1.346  -1.320  -1.177  -1.696  -1.636  -1.400  -1.347  -1.297  -1.106
138   G         1.055   1.071   1.116   1.093   1.118   1.184   1.110   1.133   1.194
139   I         0.033  -0.068  -0.021  -0.103  -0.320  -0.280  -0.172  -0.360  -0.316
140   T        -0.582  -0.502  -0.619  -0.533  -0.387  -0.574  -0.706  -0.574  -0.739
141   V        -1.661  -1.688  -1.543  -1.586  -1.627  -1.435  -1.453  -1.454  -1.257
142   E        -1.976  -1.986  -1.848  -1.682  -1.715  -1.539  -1.560  -1.553  -1.364
143   V         0.370   0.434   0.103   0.480   0.557   0.088   0.362   0.452  -0.093
144   P         1.055   1.071   1.116   1.099   1.122   1.190   1.110   1.133   1.194
145   F         1.055   1.071   1.116   0.920   0.958   1.032   1.110   1.133   1.194
146   P         1.055   1.071   1.116   1.099   1.122   1.190   1.110   1.133   1.194
147   S        -1.150  -1.109  -1.153  -1.053  -1.028  -1.048  -1.133  -1.106  -1.083
148   L        -1.227  -1.281  -1.155  -1.399  -1.449  -1.222  -1.240  -1.260  -1.085
149   K        -1.661  -1.610  -1.521  -1.470  -1.370  -1.262  -1.453  -1.374  -1.239
150   T        -1.150  -0.931  -1.109  -1.042  -0.714  -0.974  -1.133  -0.861  -1.034
151   M         0.370   0.320   0.087   0.594   0.531   0.154   0.362   0.284  -0.122
152   A        -1.661  -1.623  -1.537  -1.743  -1.679  -1.495  -1.453  -1.401  -1.252
153   L        -1.661  -1.632  -1.541  -1.784  -1.742  -1.561  -1.453  -1.407  -1.256
154   E        -0.835  -0.742  -0.679  -0.856  -0.733  -0.660  -1.026  -0.913  -0.820
155   I        -0.582  -0.521  -0.655  -0.658  -0.593  -0.798  -0.706  -0.636  -0.790
156   G        -1.465  -1.418  -1.506  -1.288  -1.240  -1.317  -1.240  -1.201  -1.225
157   L        -0.582  -0.593  -0.644  -0.784  -0.781  -0.838  -0.706  -0.703  -0.773
158   F         1.055   1.071   1.116   0.920   0.958   1.032   1.110   1.133   1.194
159   F         1.055   1.071   1.116   0.920   0.958   1.032   1.110   1.133   1.194
160   V         0.033   0.030  -0.006  -0.045  -0.062  -0.174  -0.172  -0.188  -0.288
161   L        -0.282  -0.317  -0.595  -0.291  -0.324  -0.641  -0.279  -0.330  -0.706
162   E         1.055   1.071   1.116   1.095   1.123   1.186   1.110   1.133   1.194
163   D         1.055   1.071   1.116   1.155   1.171   1.239   1.110   1.133   1.194
164   T        -0.716  -0.568  -0.650  -0.823  -0.641  -0.682  -0.919  -0.752  -0.789
165   W         1.055   1.071   1.116   1.118   1.136   1.206   1.110   1.133   1.194
166   H         1.055   1.071   1.116   1.033   1.057   1.131   1.110   1.133   1.194
167   Y         1.055   1.071   1.116   1.051   1.082   1.148   1.110   1.133   1.194
168   W         1.055   1.071   1.116   1.118   1.136   1.206   1.110   1.133   1.194
169   A        -1.227  -1.263  -1.157  -1.453  -1.471  -1.297  -1.240  -1.243  -1.087
170   H         1.055   1.071   1.116   1.033   1.057   1.131   1.110   1.133   1.194
171   R         1.055   1.071   1.116   1.185   1.203   1.266   1.110   1.133   1.194
172   L        -0.835  -0.822  -0.709  -1.192  -1.173  -0.968  -1.026  -1.008  -0.857
173   F        -0.205  -0.154  -0.035  -0.726  -0.627  -0.418  -0.599  -0.518  -0.341
174   H         1.055   1.071   1.116   1.033   1.057   1.131   1.110   1.133   1.194
175   Y         0.370   0.434   0.103   0.453   0.542   0.063   0.362   0.452  -0.093
176   G         1.055   1.071   1.116   1.093   1.118   1.184   1.110   1.133   1.194
177   V        -0.582  -0.730  -0.677  -0.542  -0.781  -0.705  -0.706  -0.898  -0.818
178   F         0.370   0.281   0.086   0.293   0.185  -0.153   0.362   0.226  -0.124
179   Y         1.055   1.071   1.116   1.051   1.082   1.148   1.110   1.133   1.194
180   K         0.370   0.242   0.084   0.492   0.337   0.100   0.362   0.164  -0.126
181   Y        -0.897  -1.115  -1.143  -0.757  -1.103  -1.209  -0.813  -1.061  -1.070
182   I         1.055   1.071   1.116   1.045   1.064   1.142   1.110   1.133   1.194
183   H         1.055   1.071   1.116   1.033   1.057   1.131   1.110   1.133   1.194
184   K         1.055   1.071   1.116   1.068   1.097   1.162   1.110   1.133   1.194
185   Q        -0.282  -0.486  -0.620  -0.010  -0.299  -0.547  -0.279  -0.552  -0.740
186   H         1.055   1.071   1.116   1.033   1.057   1.131   1.110   1.133   1.194
187   H         1.055   1.071   1.116   1.033   1.057   1.131   1.110   1.133   1.194
188   R         0.370   0.281   0.086   0.597   0.481   0.171   0.362   0.226  -0.124
189   Y         1.055   1.071   1.116   1.051   1.082   1.148   1.110   1.133   1.194
190   A         0.033  -0.068  -0.021  -0.133  -0.313  -0.234  -0.172  -0.360  -0.316
191   A         1.055   1.071   1.116   0.939   0.958   1.049   1.110   1.133   1.194
192   P         1.055   1.071   1.116   1.099   1.122   1.190   1.110   1.133   1.194
193   F         1.055   1.071   1.116   0.920   0.958   1.032   1.110   1.133   1.194
194   G         1.055   1.071   1.116   1.093   1.118   1.184   1.110   1.133   1.194
195   L         1.055   1.071   1.116   0.831   0.866   0.953   1.110   1.133   1.194
196   S        -0.912  -0.810  -0.704  -1.113  -0.941  -0.798  -1.133  -1.001  -0.851
197   A         1.055   1.071   1.116   0.939   0.958   1.049   1.110   1.133   1.194
198   E         1.055   1.071   1.116   1.095   1.123   1.186   1.110   1.133   1.194
199   Y         1.055   1.071   1.116   1.051   1.082   1.148   1.110   1.133   1.194
200   A         1.055   1.071   1.116   0.939   0.958   1.049   1.110   1.133   1.194
201   H         0.370   0.281   0.086   0.438   0.328   0.027   0.362   0.226  -0.124
202   P         1.055   1.071   1.116   1.099   1.122   1.190   1.110   1.133   1.194
203   A        -1.346  -1.233  -1.166  -1.542  -1.406  -1.282  -1.347  -1.235  -1.096
204   E         1.055   1.071   1.116   1.095   1.123   1.186   1.110   1.133   1.194
205   T        -0.716  -0.696  -0.654  -0.778  -0.715  -0.660  -0.919  -0.848  -0.787
206   L        -1.346  -1.310  -1.160  -1.476  -1.391  -1.194  -1.347  -1.282  -1.089
207   S        -0.148   0.018   0.022  -0.540  -0.255  -0.245  -0.492  -0.208  -0.237
208   L         1.055   1.071   1.116   0.831   0.866   0.953   1.110   1.133   1.194
209   G         1.055   1.071   1.116   1.093   1.118   1.184   1.110   1.133   1.194
210   F        -1.465  -1.597  -1.533  -1.464  -1.683  -1.617  -1.240  -1.362  -1.249
211   G         1.055   1.071   1.116   1.093   1.118   1.184   1.110   1.133   1.194
212   T         1.055   1.071   1.116   1.112   1.135   1.201   1.110   1.133   1.194
213   V         1.055   1.071   1.116   1.076   1.096   1.170   1.110   1.133   1.194
214   G         0.370   0.242   0.084   0.479   0.306   0.023   0.362   0.164  -0.126
215   M        -1.227  -1.285  -1.166  -1.154  -1.234  -1.062  -1.240  -1.260  -1.094
216   P         1.055   1.071   1.116   1.099   1.122   1.190   1.110   1.133   1.194
217   I         0.370   0.242   0.084   0.419   0.233  -0.049   0.362   0.164  -0.126
218   L        -1.661  -1.632  -1.541  -1.786  -1.722  -1.575  -1.453  -1.407  -1.256
219   Y        -0.148   0.018   0.022  -0.291   0.001  -0.023  -0.492  -0.208  -0.237
220   V        -0.148  -0.129  -0.032  -0.220  -0.196  -0.042  -0.492  -0.473  -0.337
221   M        -1.150  -1.244  -1.157  -1.076  -1.209  -1.133  -1.133  -1.210  -1.085
222   Y        -1.227  -1.265  -1.159  -1.347  -1.398  -1.273  -1.240  -1.240  -1.087
223   T         1.055   1.071   1.116   1.112   1.135   1.201   1.110   1.133   1.194
224   G        -0.582  -0.695  -0.662  -0.541  -0.711  -0.691  -0.706  -0.846  -0.801
225   K        -0.716  -0.588  -0.665  -0.647  -0.502  -0.571  -0.919  -0.785  -0.805
226   L         1.055   1.071   1.116   0.831   0.866   0.953   1.110   1.133   1.194
227   H         1.055   1.071   1.116   1.033   1.057   1.131   1.110   1.133   1.194
228   L         1.055   1.071   1.116   0.831   0.866   0.953   1.110   1.133   1.194
229   F        -0.282  -0.486  -0.620  -0.277  -0.553  -0.778  -0.279  -0.552  -0.740
230   T         1.055   1.071   1.116   1.112   1.135   1.201   1.110   1.133   1.194
231   L        -0.912  -0.867  -0.708  -1.175  -1.044  -0.803  -1.133  -1.068  -0.856
232   C        -0.835  -0.857  -0.711  -0.791  -0.871  -0.678  -1.026  -1.056  -0.860
233   V        -0.716  -0.596  -0.664  -0.862  -0.710  -0.792  -0.919  -0.790  -0.805
234   W         1.055   1.071   1.116   1.118   1.136   1.206   1.110   1.133   1.194
235   I         1.055   1.071   1.116   1.045   1.064   1.142   1.110   1.133   1.194
236   T        -0.897  -0.967  -1.118  -0.665  -0.785  -1.053  -0.813  -0.895  -1.043
237   L         0.370   0.510   0.104   0.257   0.430  -0.060   0.362   0.556  -0.091
238   R         1.055   1.071   1.116   1.185   1.203   1.266   1.110   1.133   1.194
239   L         1.055   1.071   1.116   0.831   0.866   0.953   1.110   1.133   1.194
240   F         1.055   1.071   1.116   0.920   0.958   1.032   1.110   1.133   1.194
241   Q         1.055   1.071   1.116   1.171   1.194   1.253   1.110   1.133   1.194
242   A         1.055   1.071   1.116   0.939   0.958   1.049   1.110   1.133   1.194
243   V         0.033  -0.033  -0.018  -0.005  -0.134  -0.135  -0.172  -0.298  -0.310
244   D         1.055   1.071   1.116   1.155   1.171   1.239   1.110   1.133   1.194
245   S        -0.148  -0.141  -0.038  -0.401  -0.415  -0.253  -0.492  -0.495  -0.347
246   H         1.055   1.071   1.116   1.033   1.057   1.131   1.110   1.133   1.194
247   S         0.370   0.242   0.084   0.448   0.277   0.003   0.362   0.164  -0.126
248   G         1.055   1.071   1.116   1.093   1.118   1.184   1.110   1.133   1.194
249   Y         1.055   1.071   1.116   1.051   1.082   1.148   1.110   1.133   1.194
250   D        -0.148  -0.109  -0.027  -0.236  -0.181  -0.071  -0.492  -0.435  -0.327
251   F         1.055   1.071   1.116   0.920   0.958   1.032   1.110   1.133   1.194
252   P         1.055   1.071   1.116   1.099   1.122   1.190   1.110   1.133   1.194
253   W        -0.282  -0.418  -0.614  -0.083  -0.280  -0.623  -0.279  -0.460  -0.732
254   S         1.055   1.071   1.116   1.060   1.089   1.155   1.110   1.133   1.194
255   L         1.055   1.071   1.116   0.831   0.866   0.953   1.110   1.133   1.194
256   N        -0.716  -0.743  -0.678  -0.696  -0.716  -0.615  -0.919  -0.930  -0.821
257   K        -0.716  -0.650  -0.667  -0.801  -0.719  -0.680  -0.919  -0.844  -0.809
258   I         0.370   0.526   0.108   0.324   0.523  -0.035   0.362   0.577  -0.085
259   M        -0.282  -0.090  -0.567  -0.323  -0.083  -0.672  -0.279  -0.033  -0.669
260   P         1.055   1.071   1.116   1.099   1.122   1.190   1.110   1.133   1.194
261   F         0.033  -0.052  -0.020  -0.157  -0.297  -0.254  -0.172  -0.331  -0.314
262   W         1.055   1.071   1.116   1.118   1.136   1.206   1.110   1.133   1.194
263   A        -0.282  -0.248  -0.591  -0.206  -0.168  -0.603  -0.279  -0.248  -0.701
264   G         1.055   1.071   1.116   1.093   1.118   1.184   1.110   1.133   1.194
265   A         1.055   1.071   1.116   0.939   0.958   1.049   1.110   1.133   1.194
266   E        -0.205  -0.149  -0.034  -0.358  -0.261  -0.085  -0.599  -0.509  -0.339
267   H         1.055   1.071   1.116   1.033   1.057   1.131   1.110   1.133   1.194
268   H         1.055   1.071   1.116   1.033   1.057   1.131   1.110   1.133   1.194
269   D         1.055   1.071   1.116   1.155   1.171   1.239   1.110   1.133   1.194
270   L        -1.150  -1.221  -1.158  -1.265  -1.336  -1.204  -1.133  -1.186  -1.086
271   H         1.055   1.071   1.116   1.033   1.057   1.131   1.110   1.133   1.194
272   H         1.055   1.071   1.116   1.033   1.057   1.131   1.110   1.133   1.194
273   H        -0.897  -1.115  -1.143  -0.661  -0.954  -0.990  -0.813  -1.061  -1.070
274   Y        -0.897  -1.031  -1.121  -0.726  -0.928  -1.106  -0.813  -0.971  -1.046
275   F         1.055   1.071   1.116   0.920   0.958   1.032   1.110   1.133   1.194
276   I        -0.282  -0.453  -0.619  -0.125  -0.360  -0.618  -0.279  -0.508  -0.739
277   G         0.370   0.242   0.084   0.512   0.351   0.109   0.362   0.164  -0.126
278   N        -0.282  -0.170  -0.589   0.025   0.175  -0.458  -0.279  -0.133  -0.698
279   Y         0.370   0.242   0.084   0.437   0.271  -0.011   0.362   0.164  -0.126
280   A        -0.148  -0.129  -0.032  -0.444  -0.422  -0.252  -0.492  -0.473  -0.337
281   S         1.055   1.071   1.116   1.060   1.089   1.155   1.110   1.133   1.194
282   S         1.055   1.071   1.116   1.060   1.089   1.155   1.110   1.133   1.194
283   F         1.055   1.071   1.116   0.920   0.958   1.032   1.110   1.133   1.194
284   R         1.055   1.071   1.116   1.185   1.203   1.266   1.110   1.133   1.194
285   W         1.055   1.071   1.116   1.118   1.136   1.206   1.110   1.133   1.194
286   W         1.055   1.071   1.116   1.118   1.136   1.206   1.110   1.133   1.194
287   D         1.055   1.071   1.116   1.155   1.171   1.239   1.110   1.133   1.194
288   Y        -0.716  -0.768  -0.680  -0.938  -1.002  -0.872  -0.919  -0.956  -0.823
289   C        -0.716  -0.613  -0.653  -0.690  -0.553  -0.586  -0.919  -0.784  -0.790
290   L         1.055   1.071   1.116   0.831   0.866   0.953   1.110   1.133   1.194
291   D         0.370   0.242   0.084   0.561   0.388   0.128   0.362   0.164  -0.126
292   T         1.055   1.071   1.116   1.112   1.135   1.201   1.110   1.133   1.194
293   E         0.370   0.242   0.084   0.514   0.356   0.111   0.362   0.164  -0.126
294   S        -0.582  -0.535  -0.618  -0.662  -0.566  -0.677  -0.706  -0.618  -0.737
295   G         0.370   0.242   0.084   0.519   0.364   0.127   0.362   0.164  -0.126
296   P        -0.282  -0.486  -0.620  -0.077  -0.357  -0.591  -0.279  -0.552  -0.740
297   E        -1.150  -1.221  -1.158  -1.091  -1.196  -1.143  -1.133  -1.186  -1.086
298   A        -0.282  -0.353  -0.595  -0.216  -0.313  -0.629  -0.279  -0.381  -0.707
299   K        -0.282  -0.486  -0.620  -0.155  -0.452  -0.725  -0.279  -0.552  -0.740
300   A        -1.227  -1.051  -1.134  -1.318  -1.070  -1.134  -1.240  -1.055  -1.065
301   S        -1.346  -1.206  -1.160  -1.464  -1.265  -1.163  -1.347  -1.184  -1.090
302   R         1.055   1.071   1.116   1.185   1.203   1.266   1.110   1.133   1.194
303   E         0.236   0.088   0.017   0.343   0.136   0.000   0.160  -0.087  -0.247
304   E        -0.784  -0.758  -0.699  -0.779  -0.740  -0.639  -0.979  -0.949  -0.845
305   R         0.033   0.113   0.035   0.107   0.227   0.062  -0.172  -0.045  -0.214
306   M        -1.150  -1.196  -1.157  -1.049  -1.192  -1.115  -1.133  -1.185  -1.087
307   K         0.033  -0.052  -0.020  -0.047  -0.215  -0.202  -0.172  -0.331  -0.314
308   K        -2.095  -1.871  -1.842  -2.045  -1.747  -1.680  -1.667  -1.475  -1.360
309   R        -0.897  -0.801  -1.091  -0.675  -0.577  -0.981  -0.813  -0.710  -1.015
310   A        -0.282  -0.347  -0.597  -0.239  -0.338  -0.683  -0.279  -0.375  -0.710
311   E         0.033  -0.033  -0.018  -0.021  -0.154  -0.177  -0.172  -0.298  -0.310
312   N        -1.626  -1.511  -1.522  -1.440  -1.343  -1.318  -1.401  -1.293  -1.240
313   N        -1.042  -0.997  -1.120  -0.903  -0.864  -1.064  -0.983  -0.940  -1.046
314   A        -0.582  -0.559  -0.657  -0.662  -0.656  -0.742  -0.706  -0.695  -0.794
315   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
316   K         1.055   1.071   1.116   1.068   1.097   1.162   1.110   1.133   1.194
317   K         1.055   1.071   1.116   1.068   1.097   1.162   1.110   1.133   1.194
318   T        -1.346  -1.191  -1.151  -1.370  -1.164  -1.051  -1.347  -1.170  -1.080
319   N        -1.346  -1.353  -1.178  -1.344  -1.340  -1.110  -1.347  -1.327  -1.106
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P53045
Output conservation file - output/P53045
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
