1     M         2.377   2.399   2.483   2.692   2.724   2.869   2.724   2.762   2.914
2     V        -1.404  -1.399  -1.367  -1.463  -1.453  -1.406  -1.072  -1.064  -1.012
3     K         0.882   0.909   0.905   0.887   0.936   0.898   0.615   0.662   0.623
4     G         0.882   0.909   0.905   0.700   0.743   0.730   0.615   0.662   0.623
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     S        -0.753  -0.775  -0.761  -0.619  -0.639  -0.630  -0.693  -0.717  -0.686
7     V         1.201   1.268   1.136   0.886   0.983   0.787   1.205   1.320   1.070
8     H         1.201   1.241   1.128   1.618   1.681   1.515   1.205   1.274   1.055
9     L         0.796   0.781   0.837   0.269   0.253   0.333   0.446   0.408   0.484
10    W         2.377   2.399   2.483   2.759   2.794   2.937   2.724   2.762   2.914
11    G         2.377   2.399   2.483   2.608   2.641   2.782   2.724   2.762   2.914
12    K         0.144   0.124   0.066   0.057   0.035  -0.092   0.067   0.036  -0.049
13    D         0.144   0.124   0.066   0.269   0.238   0.138   0.067   0.036  -0.049
14    G        -0.066  -0.108  -0.075  -0.079  -0.167  -0.131  -0.242  -0.302  -0.258
15    K        -0.753  -0.747  -0.739  -0.697  -0.686  -0.672  -0.693  -0.684  -0.661
16    A        -0.753  -0.782  -0.763  -0.589  -0.655  -0.609  -0.693  -0.724  -0.688
17    S         1.201   1.141   1.109   1.044   0.940   0.855   1.205   1.097   1.020
18    L        -0.753  -0.788  -0.771  -0.931  -0.969  -0.923  -0.693  -0.731  -0.698
19    I         0.144   0.124   0.066   0.329   0.298   0.213   0.067   0.036  -0.049
20    S         2.377   2.399   2.483   2.291   2.324   2.456   2.724   2.762   2.914
21    V        -0.753  -0.747  -0.739  -0.445  -0.437  -0.416  -0.693  -0.684  -0.661
22    D        -0.753  -0.775  -0.761  -0.726  -0.759  -0.737  -0.693  -0.717  -0.686
23    S         0.796   0.781   0.837   0.663   0.649   0.743   0.446   0.408   0.484
24    I         1.201   1.141   1.109   1.247   1.140   1.062   1.205   1.097   1.020
25    A         2.377   2.399   2.483   2.544   2.573   2.716   2.724   2.762   2.914
26    L         0.144   0.069   0.038  -0.213  -0.325  -0.388   0.067  -0.043  -0.091
27    V        -1.404  -1.399  -1.367  -1.079  -1.076  -1.011  -1.072  -1.064  -1.012
28    W         1.201   1.182   1.111   1.622   1.597   1.490   1.205   1.170   1.023
29    F        -0.101  -0.067  -0.063  -0.409  -0.361  -0.346  -0.313  -0.271  -0.254
30    I         0.144   0.135   0.079  -0.078  -0.084  -0.157   0.067   0.051  -0.029
31    K         0.144   0.069   0.038   0.162   0.046  -0.006   0.067  -0.043  -0.091
32    L         0.882   0.905   0.924   0.451   0.483   0.507   0.615   0.654   0.662
33    C         0.882   0.905   0.924   1.078   1.117   1.138   0.615   0.654   0.662
34    T        -0.204  -0.198  -0.145  -0.534  -0.524  -0.451  -0.439  -0.430  -0.358
35    S        -0.204  -0.198  -0.145  -0.430  -0.421  -0.343  -0.439  -0.430  -0.358
36    E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
37    E        -0.204  -0.194  -0.145  -0.214  -0.194  -0.122  -0.439  -0.425  -0.358
38    A        -0.204  -0.194  -0.145  -0.206  -0.203  -0.113  -0.439  -0.425  -0.358
39    K        -0.880  -0.873  -0.833  -1.007  -0.999  -0.938  -0.835  -0.825  -0.767
40    S        -0.204  -0.197  -0.145  -0.511  -0.499  -0.427  -0.439  -0.430  -0.358
41    M         0.882   0.909   0.905   1.014   1.058   1.052   0.615   0.662   0.623
42    V        -0.204  -0.197  -0.145  -0.778  -0.781  -0.702  -0.439  -0.430  -0.358
43    A        -0.204  -0.197  -0.145  -0.120  -0.110  -0.025  -0.439  -0.430  -0.358
44    G        -0.753  -0.740  -0.752  -0.636  -0.624  -0.623  -0.693  -0.676  -0.676
45    L        -0.101  -0.064  -0.073  -0.222  -0.147  -0.195  -0.313  -0.265  -0.266
46    Q        -0.101  -0.129  -0.081  -0.145  -0.189  -0.110  -0.313  -0.343  -0.275
47    I         0.796   0.797   0.848   0.678   0.672   0.746   0.446   0.440   0.508
48    V         1.201   1.182   1.111   1.348   1.323   1.214   1.205   1.170   1.023
49    F        -0.753  -0.782  -0.763  -0.449  -0.494  -0.456  -0.693  -0.724  -0.688
50    S         1.201   1.241   1.128   1.175   1.233   1.073   1.205   1.274   1.055
51    N         1.201   1.141   1.109   1.225   1.133   1.067   1.205   1.097   1.020
52    N         2.377   2.399   2.483   2.406   2.441   2.574   2.724   2.762   2.914
53    T         1.201   1.141   1.109   1.350   1.256   1.202   1.205   1.097   1.020
54    D         0.144   0.069   0.038   0.309   0.196   0.142   0.067  -0.043  -0.091
55    L         1.201   1.241   1.128   0.890   0.948   0.780   1.205   1.274   1.055
56    S         1.201   1.141   1.109   1.175   1.089   1.043   1.205   1.097   1.020
57    S        -0.066  -0.079  -0.065  -0.018  -0.041  -0.040  -0.242  -0.262  -0.243
58    D        -0.880  -0.873  -0.833  -1.053  -1.037  -0.985  -0.835  -0.825  -0.767
59    G         1.201   1.182   1.111   1.453   1.426   1.311   1.205   1.170   1.023
60    K        -0.753  -0.727  -0.749  -0.677  -0.635  -0.664  -0.693  -0.660  -0.672
61    L         2.377   2.399   2.483   2.017   2.050   2.174   2.724   2.762   2.914
62    P         2.377   2.399   2.483   2.608   2.640   2.782   2.724   2.762   2.914
63    V         0.144   0.124   0.066   0.372   0.351   0.269   0.067   0.036  -0.049
64    L         2.377   2.399   2.483   2.017   2.050   2.174   2.724   2.762   2.914
65    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
66    I        -0.066  -0.088  -0.075  -0.056  -0.099  -0.079  -0.242  -0.275  -0.258
67    L        -1.404  -1.399  -1.367  -1.377  -1.363  -1.318  -1.072  -1.064  -1.012
68    D        -0.753  -0.727  -0.749  -0.713  -0.671  -0.718  -0.693  -0.660  -0.672
69    N        -0.101  -0.109  -0.077  -0.316  -0.326  -0.275  -0.313  -0.319  -0.270
70    G        -0.753  -0.782  -0.763  -0.586  -0.650  -0.614  -0.693  -0.724  -0.688
71    T        -0.753  -0.727  -0.749  -0.757  -0.723  -0.749  -0.693  -0.660  -0.672
72    K         0.144   0.204   0.094   0.172   0.259   0.095   0.067   0.156  -0.008
73    V        -0.753  -0.720  -0.735  -0.593  -0.542  -0.561  -0.693  -0.652  -0.656
74    S        -1.404  -1.399  -1.367  -1.127  -1.107  -1.060  -1.072  -1.064  -1.012
75    G         2.377   2.399   2.483   2.608   2.641   2.782   2.724   2.762   2.914
76    Y        -0.753  -0.754  -0.747  -0.718  -0.712  -0.721  -0.693  -0.692  -0.671
77    V        -1.404  -1.399  -1.367  -1.522  -1.509  -1.467  -1.072  -1.064  -1.012
78    N        -0.101  -0.109  -0.077  -0.364  -0.377  -0.331  -0.313  -0.319  -0.270
79    I         2.377   2.399   2.483   2.493   2.523   2.663   2.724   2.762   2.914
80    V         0.796   0.833   0.867   0.678   0.741   0.783   0.446   0.512   0.545
81    Q        -0.753  -0.688  -0.742  -0.533  -0.420  -0.515  -0.693  -0.613  -0.664
82    F        -0.101  -0.075  -0.066   0.043   0.074   0.114  -0.313  -0.279  -0.257
83    L         1.201   1.182   1.111   0.890   0.864   0.753   1.205   1.170   1.023
84    H        -0.753  -0.740  -0.752  -0.643  -0.641  -0.631  -0.693  -0.676  -0.676
85    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
86    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
87    I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
88    C        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
89    T        -0.066  -0.017  -0.044  -0.120  -0.054  -0.082  -0.242  -0.170  -0.212
90    S        -0.066  -0.071  -0.055  -0.463  -0.489  -0.486  -0.242  -0.249  -0.228
91    K        -0.880  -0.875  -0.833  -0.759  -0.743  -0.682  -0.835  -0.827  -0.767
92    Y        -0.880  -0.875  -0.833  -0.968  -0.944  -0.897  -0.835  -0.827  -0.767
93    E        -0.880  -0.875  -0.833  -1.036  -1.027  -0.967  -0.835  -0.827  -0.767
94    K        -0.880  -0.875  -0.833  -1.203  -1.211  -1.139  -0.835  -0.827  -0.767
95    G        -0.880  -0.875  -0.833  -0.814  -0.813  -0.739  -0.835  -0.827  -0.767
96    T         1.056   1.020   1.021   1.177   1.113   1.117   0.944   0.873   0.852
97    D         1.056   1.060   1.035   1.057   1.063   1.004   0.944   0.949   0.879
98    Y        -0.066  -0.017  -0.044  -0.328  -0.267  -0.286  -0.242  -0.170  -0.212
99    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
100   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
101   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
102   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
103   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
104   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
105   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
106   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
107   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
108   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
109   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
110   V        -0.204  -0.194  -0.145  -0.194  -0.183  -0.101  -0.439  -0.425  -0.358
111   R        -0.066  -0.000  -0.044   0.017   0.119   0.054  -0.242  -0.145  -0.212
112   K        -0.880  -0.873  -0.833  -1.062  -1.054  -0.993  -0.835  -0.825  -0.767
113   K         0.749   0.760   0.825   0.501   0.516   0.614   0.351   0.367   0.460
114   D         0.144   0.226   0.093   0.192   0.316   0.113   0.067   0.188  -0.009
115   R         0.144   0.135   0.079   0.224   0.207   0.137   0.067   0.051  -0.029
116   L         1.201   1.141   1.109   0.890   0.805   0.751   1.205   1.097   1.020
117   L        -0.753  -0.788  -0.771  -0.964  -1.014  -0.961  -0.693  -0.731  -0.698
118   E        -0.101  -0.070  -0.074  -0.332  -0.280  -0.296  -0.313  -0.273  -0.266
119   Y        -1.404  -1.399  -1.367  -1.587  -1.565  -1.535  -1.072  -1.064  -1.012
120   S        -0.101  -0.109  -0.077  -0.180  -0.181  -0.126  -0.313  -0.319  -0.270
121   L         1.201   1.241   1.128   0.904   0.961   0.799   1.205   1.274   1.055
122   L         0.144   0.146   0.065  -0.078  -0.078  -0.175   0.067   0.070  -0.050
123   N        -0.753  -0.754  -0.747  -0.702  -0.700  -0.693  -0.693  -0.692  -0.671
124   Y        -0.753  -0.734  -0.741  -0.656  -0.641  -0.641  -0.693  -0.668  -0.664
125   V        -0.753  -0.740  -0.752  -0.905  -0.877  -0.879  -0.693  -0.676  -0.676
126   D        -0.066  -0.090  -0.067  -0.140  -0.185  -0.164  -0.242  -0.277  -0.245
127   V        -0.753  -0.720  -0.735  -0.854  -0.802  -0.828  -0.693  -0.652  -0.656
128   E        -0.753  -0.788  -0.771  -0.873  -0.942  -0.922  -0.693  -0.731  -0.698
129   I         0.144   0.167   0.081  -0.115  -0.081  -0.200   0.067   0.101  -0.026
130   S        -0.753  -0.775  -0.761  -0.820  -0.849  -0.839  -0.693  -0.717  -0.686
131   R         0.144   0.167   0.081   0.356   0.388   0.265   0.067   0.101  -0.026
132   L        -0.101  -0.070  -0.074  -0.354  -0.294  -0.282  -0.313  -0.273  -0.266
133   T         0.796   0.805   0.849   0.650   0.662   0.717   0.446   0.458   0.510
134   D        -0.753  -0.720  -0.735  -0.582  -0.539  -0.542  -0.693  -0.652  -0.656
135   Y         2.377   2.399   2.483   2.501   2.534   2.672   2.724   2.762   2.914
136   Q         0.144   0.069   0.038   0.416   0.306   0.260   0.067  -0.043  -0.091
137   L         2.377   2.399   2.483   2.017   2.050   2.174   2.724   2.762   2.914
138   F         0.796   0.800   0.849   0.746   0.748   0.822   0.446   0.447   0.509
139   L         1.201   1.141   1.109   0.886   0.802   0.746   1.205   1.097   1.020
140   N         0.796   0.794   0.843   0.608   0.601   0.670   0.446   0.434   0.497
141   T        -1.404  -1.399  -1.367  -1.274  -1.278  -1.212  -1.072  -1.064  -1.012
142   K        -0.753  -0.754  -0.747  -0.805  -0.811  -0.800  -0.693  -0.692  -0.671
143   N         1.201   1.141   1.109   1.288   1.203   1.157   1.205   1.097   1.020
144   Y         2.377   2.399   2.483   2.501   2.534   2.672   2.724   2.762   2.914
145   N        -0.753  -0.788  -0.771  -0.688  -0.741  -0.713  -0.693  -0.731  -0.698
146   E        -0.753  -0.788  -0.771  -0.779  -0.844  -0.813  -0.693  -0.731  -0.698
147   Y         0.144   0.114   0.071   0.337   0.288   0.228   0.067   0.022  -0.042
148   T         2.377   2.399   2.483   2.510   2.541   2.681   2.724   2.762   2.914
149   K         0.144   0.226   0.093   0.299   0.438   0.196   0.067   0.188  -0.009
150   K         1.201   1.141   1.109   1.248   1.163   1.123   1.205   1.097   1.020
151   L        -0.753  -0.754  -0.747  -0.950  -0.938  -0.925  -0.693  -0.692  -0.671
152   F         0.144   0.204   0.094   0.253   0.353   0.144   0.067   0.156  -0.008
153   S         1.201   1.141   1.109   1.140   1.051   0.993   1.205   1.097   1.020
154   K        -1.404  -1.399  -1.367  -1.365  -1.367  -1.306  -1.072  -1.064  -1.012
155   L         0.144   0.069   0.038  -0.112  -0.214  -0.255   0.067  -0.043  -0.091
156   L         1.201   1.141   1.109   0.944   0.867   0.828   1.205   1.097   1.020
157   Y        -0.101  -0.070  -0.074   0.058   0.103   0.125  -0.313  -0.273  -0.266
158   F         1.201   1.254   1.134   1.518   1.591   1.445   1.205   1.296   1.067
159   P         1.201   1.141   1.109   1.363   1.256   1.179   1.205   1.097   1.020
160   M         0.796   0.828   0.866   0.906   0.960   1.016   0.446   0.503   0.544
161   W        -0.753  -0.788  -0.771  -0.319  -0.373  -0.347  -0.693  -0.731  -0.698
162   Y         1.201   1.241   1.128   1.392   1.450   1.295   1.205   1.274   1.055
163   N         2.377   2.399   2.483   2.406   2.441   2.574   2.724   2.762   2.914
164   T        -0.753  -0.788  -0.771  -0.543  -0.600  -0.564  -0.693  -0.731  -0.698
165   P         0.144   0.114   0.071   0.366   0.306   0.237   0.067   0.022  -0.042
166   L        -0.753  -0.788  -0.771  -1.087  -1.129  -1.102  -0.693  -0.731  -0.698
167   Q        -1.404  -1.399  -1.367  -1.312  -1.295  -1.251  -1.072  -1.064  -1.012
168   L        -0.101  -0.075  -0.070  -0.426  -0.397  -0.380  -0.313  -0.280  -0.262
169   R         1.201   1.182   1.111   1.467   1.444   1.335   1.205   1.170   1.023
170   S        -0.753  -0.788  -0.771  -0.825  -0.879  -0.851  -0.693  -0.731  -0.698
171   Q         0.796   0.828   0.866   0.800   0.853   0.908   0.446   0.503   0.544
172   A         2.377   2.399   2.483   2.544   2.573   2.716   2.724   2.762   2.914
173   R        -0.101  -0.108  -0.072  -0.120  -0.135  -0.075  -0.313  -0.318  -0.264
174   E         1.201   1.141   1.109   1.248   1.159   1.111   1.205   1.097   1.020
175   N        -0.753  -0.740  -0.752  -0.724  -0.684  -0.742  -0.693  -0.676  -0.676
176   C         1.201   1.182   1.111   1.605   1.578   1.471   1.205   1.170   1.023
177   E        -1.404  -1.399  -1.367  -1.120  -1.098  -1.054  -1.072  -1.064  -1.012
178   E        -0.753  -0.775  -0.761  -0.626  -0.659  -0.640  -0.693  -0.717  -0.686
179   I        -0.066  -0.108  -0.075  -0.234  -0.327  -0.290  -0.242  -0.302  -0.258
180   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
181   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
182   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
183   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
184   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
185   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
186   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
187   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
188   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
189   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
190   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
191   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
192   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
193   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
194   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
195   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
196   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
197   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
198   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
199   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
200   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
201   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
202   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
203   I        -0.753  -0.727  -0.749  -0.624  -0.571  -0.639  -0.693  -0.660  -0.672
204   G        -0.753  -0.688  -0.742  -0.560  -0.458  -0.540  -0.693  -0.613  -0.664
205   S        -0.753  -0.734  -0.741  -0.702  -0.674  -0.673  -0.693  -0.668  -0.664
206   L        -0.753  -0.782  -0.763  -1.036  -1.075  -1.036  -0.693  -0.724  -0.688
207   T        -0.753  -0.775  -0.761  -0.622  -0.679  -0.653  -0.693  -0.717  -0.686
208   L         0.144   0.204   0.094  -0.193  -0.102  -0.276   0.067   0.156  -0.008
209   E        -0.753  -0.782  -0.763  -0.684  -0.729  -0.693  -0.693  -0.724  -0.688
210   D        -0.101  -0.064  -0.073  -0.261  -0.205  -0.212  -0.313  -0.265  -0.266
211   D        -0.753  -0.754  -0.747  -0.658  -0.651  -0.652  -0.693  -0.692  -0.671
212   E         0.144   0.124   0.066   0.124   0.085  -0.016   0.067   0.036  -0.049
213   E        -0.101  -0.129  -0.081  -0.159  -0.188  -0.110  -0.313  -0.343  -0.275
214   F        -0.880  -0.873  -0.833  -0.926  -0.913  -0.854  -0.835  -0.825  -0.767
215   V        -0.880  -0.873  -0.833  -0.845  -0.838  -0.771  -0.835  -0.825  -0.767
216   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
217   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
218   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
219   E         1.056   1.088   1.021   1.037   1.083   0.981   0.944   1.000   0.852
220   S        -0.066  -0.079  -0.065  -0.069  -0.078  -0.080  -0.242  -0.262  -0.243
221   K        -0.066  -0.023  -0.055  -0.158  -0.080  -0.162  -0.242  -0.179  -0.228
222   A        -0.204  -0.194  -0.145  -0.544  -0.532  -0.461  -0.439  -0.425  -0.358
223   M        -0.880  -0.873  -0.833  -0.713  -0.703  -0.635  -0.835  -0.825  -0.767
224   E         1.056   1.091   1.025   1.052   1.103   1.006   0.944   1.006   0.860
225   S        -0.880  -0.873  -0.833  -0.935  -0.915  -0.864  -0.835  -0.825  -0.767
226   A        -0.066  -0.088  -0.075   0.106   0.079   0.087  -0.242  -0.275  -0.258
227   S        -0.880  -0.873  -0.833  -0.831  -0.806  -0.756  -0.835  -0.825  -0.767
228   Q        -0.066  -0.079  -0.065  -0.174  -0.213  -0.181  -0.242  -0.262  -0.243
229   L         1.056   0.999   0.997   0.677   0.595   0.576   0.944   0.835   0.805
230   A         1.201   1.141   1.109   1.363   1.263   1.206   1.205   1.097   1.020
231   Q         0.144   0.069   0.038   0.425   0.313   0.272   0.067  -0.043  -0.091
232   S         1.201   1.141   1.109   1.192   1.109   1.067   1.205   1.097   1.020
233   K         1.201   1.182   1.111   1.169   1.137   1.013   1.205   1.170   1.023
234   T        -0.101  -0.070  -0.074  -0.444  -0.425  -0.412  -0.313  -0.273  -0.266
235   F         0.144   0.069   0.038   0.475   0.361   0.327   0.067  -0.043  -0.091
236   K        -0.753  -0.788  -0.771  -0.742  -0.800  -0.765  -0.693  -0.731  -0.698
237   I        -0.753  -0.788  -0.771  -0.715  -0.761  -0.759  -0.693  -0.731  -0.698
238   A        -1.404  -1.399  -1.367  -1.148  -1.155  -1.082  -1.072  -1.064  -1.012
239   H        -1.404  -1.399  -1.367  -1.158  -1.173  -1.093  -1.072  -1.064  -1.012
240   K        -0.753  -0.740  -0.752  -1.115  -1.099  -1.111  -0.693  -0.676  -0.676
241   N        -0.753  -0.720  -0.735  -0.684  -0.620  -0.668  -0.693  -0.652  -0.656
242   K         1.201   1.141   1.109   1.191   1.096   1.041   1.205   1.097   1.020
243   I        -0.753  -0.775  -0.761  -0.649  -0.701  -0.682  -0.693  -0.717  -0.686
244   K         0.796   0.813   0.852   0.659   0.684   0.729   0.446   0.473   0.516
245   G        -1.404  -1.399  -1.367  -1.195  -1.208  -1.131  -1.072  -1.064  -1.012
246   K        -0.753  -0.754  -0.747  -0.688  -0.694  -0.671  -0.693  -0.692  -0.671
247   Q        -0.753  -0.754  -0.747  -0.628  -0.627  -0.626  -0.693  -0.692  -0.671
248   E        -0.753  -0.782  -0.763  -0.840  -0.894  -0.870  -0.693  -0.724  -0.688
249   L         1.201   1.141   1.109   0.851   0.760   0.696   1.205   1.097   1.020
250   Q        -0.101  -0.129  -0.081  -0.154  -0.198  -0.117  -0.313  -0.343  -0.275
251   Q        -0.753  -0.747  -0.739  -0.751  -0.743  -0.731  -0.693  -0.684  -0.661
252   V        -0.101  -0.070  -0.074  -0.439  -0.390  -0.425  -0.313  -0.273  -0.266
253   K         0.796   0.805   0.849   0.625   0.637   0.705   0.446   0.458   0.510
254   Y        -0.753  -0.747  -0.739  -0.852  -0.833  -0.843  -0.693  -0.684  -0.661
255   N         0.144   0.069   0.038   0.155   0.035  -0.034   0.067  -0.043  -0.091
256   L        -1.404  -1.399  -1.367  -1.296  -1.253  -1.235  -1.072  -1.064  -1.012
257   Q        -0.753  -0.727  -0.749  -0.577  -0.534  -0.577  -0.693  -0.660  -0.672
258   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
259   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
260   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
261   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
262   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
263   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
264   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
265   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
266   F         0.796   0.837   0.873   0.746   0.813   0.867   0.446   0.521   0.559
267   D        -0.753  -0.727  -0.749  -0.505  -0.470  -0.488  -0.693  -0.660  -0.672
268   N        -1.404  -1.399  -1.367  -1.129  -1.125  -1.063  -1.072  -1.064  -1.012
269   R        -0.101  -0.130  -0.076  -0.072  -0.098  -0.011  -0.313  -0.345  -0.269
270   L         0.144   0.069   0.038  -0.046  -0.140  -0.168   0.067  -0.043  -0.091
271   Q        -0.753  -0.727  -0.749  -0.825  -0.780  -0.841  -0.693  -0.660  -0.672
272   S        -0.753  -0.688  -0.742  -0.748  -0.629  -0.743  -0.693  -0.613  -0.664
273   C        -1.404  -1.399  -1.367  -0.982  -0.983  -0.911  -1.072  -1.064  -1.012
274   V        -0.753  -0.775  -0.761  -0.946  -0.964  -0.933  -0.693  -0.717  -0.686
275   S        -1.404  -1.399  -1.367  -1.204  -1.186  -1.140  -1.072  -1.064  -1.012
276   N         0.144   0.146   0.065   0.327   0.336   0.230   0.067   0.070  -0.050
277   W         1.056   0.999   0.997   1.427   1.335   1.327   0.944   0.835   0.805
278   L        -0.880  -0.873  -0.833  -1.094  -1.058  -1.027  -0.835  -0.825  -0.767
279   A        -0.753  -0.775  -0.761  -0.700  -0.729  -0.696  -0.693  -0.717  -0.686
280   A         0.144   0.146   0.065   0.351   0.349   0.224   0.067   0.070  -0.050
281   R        -0.753  -0.788  -0.771  -0.642  -0.715  -0.693  -0.693  -0.731  -0.698
282   K        -0.753  -0.740  -0.752  -0.586  -0.559  -0.580  -0.693  -0.676  -0.676
283   K        -0.753  -0.727  -0.749  -0.875  -0.834  -0.873  -0.693  -0.660  -0.672
284   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
285   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
286   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
287   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
288   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
289   L         1.201   1.182   1.111   0.915   0.892   0.790   1.205   1.170   1.023
290   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
291   D        -0.880  -0.873  -0.833  -0.765  -0.757  -0.689  -0.835  -0.825  -0.767
292   S         0.144   0.146   0.065   0.173   0.175   0.067   0.067   0.070  -0.050
293   V        -1.404  -1.399  -1.367  -1.256  -1.248  -1.194  -1.072  -1.064  -1.012
294   I        -0.753  -0.727  -0.749  -0.555  -0.512  -0.540  -0.693  -0.660  -0.672
295   L         0.796   0.837   0.873   0.233   0.323   0.340   0.446   0.521   0.559
296   S        -0.101  -0.130  -0.076  -0.169  -0.213  -0.129  -0.313  -0.345  -0.269
297   S         0.144   0.204   0.094   0.127   0.215   0.053   0.067   0.156  -0.008
298   D         0.144   0.146   0.065   0.301   0.301   0.176   0.067   0.070  -0.050
299   L        -0.101  -0.129  -0.081  -0.457  -0.477  -0.410  -0.313  -0.343  -0.275
300   L         0.144   0.124   0.066  -0.120  -0.144  -0.226   0.067   0.036  -0.049
301   F         0.796   0.797   0.848   0.502   0.485   0.539   0.446   0.440   0.508
302   L        -0.753  -0.740  -0.752  -0.677  -0.630  -0.683  -0.693  -0.676  -0.676
303   A         1.201   1.241   1.128   1.363   1.421   1.239   1.205   1.274   1.055
304   N        -0.101  -0.068  -0.073   0.041   0.095   0.089  -0.313  -0.272  -0.266
305   L         0.144   0.146   0.065  -0.078  -0.078  -0.175   0.067   0.070  -0.050
306   Y        -0.753  -0.782  -0.763  -0.584  -0.624  -0.597  -0.693  -0.724  -0.688
307   V        -0.753  -0.788  -0.771  -0.690  -0.763  -0.728  -0.693  -0.731  -0.698
308   Q         1.201   1.182   1.111   1.312   1.277   1.131   1.205   1.170   1.023
309   L        -0.101  -0.109  -0.077  -0.294  -0.281  -0.239  -0.313  -0.319  -0.270
310   G        -1.404  -1.399  -1.367  -1.319  -1.345  -1.258  -1.072  -1.064  -1.012
311   -        -0.204  -0.197  -0.145  -0.337  -0.318  -0.248  -0.439  -0.429  -0.358
312   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
313   L         2.377   2.399   2.483   2.017   2.050   2.174   2.724   2.762   2.914
314   P         2.377   2.399   2.483   2.608   2.640   2.782   2.724   2.762   2.914
315   D         0.144   0.204   0.094   0.293   0.386   0.214   0.067   0.156  -0.008
316   G         0.882   0.876   0.895   0.903   0.887   0.896   0.615   0.598   0.602
317   N        -0.753  -0.782  -0.763  -0.522  -0.546  -0.514  -0.693  -0.724  -0.688
318   R        -1.404  -1.399  -1.367  -1.331  -1.305  -1.270  -1.072  -1.064  -1.012
319   I         0.144   0.124   0.066   0.155   0.126  -0.008   0.067   0.036  -0.049
320   R        -0.753  -0.788  -0.771  -0.357  -0.413  -0.366  -0.693  -0.731  -0.698
321   S        -0.753  -0.788  -0.771  -0.810  -0.852  -0.834  -0.693  -0.731  -0.698
322   K        -0.753  -0.740  -0.752  -0.728  -0.733  -0.739  -0.693  -0.676  -0.676
323   L         2.377   2.399   2.483   2.017   2.050   2.174   2.724   2.762   2.914
324   E         0.144   0.226   0.093   0.167   0.290   0.089   0.067   0.188  -0.009
325   Q        -1.404  -1.399  -1.367  -1.598  -1.613  -1.545  -1.072  -1.064  -1.012
326   T        -0.753  -0.688  -0.742  -0.598  -0.512  -0.565  -0.693  -0.613  -0.664
327   F        -0.753  -0.734  -0.741  -0.550  -0.517  -0.532  -0.693  -0.668  -0.664
328   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
329   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
330   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
331   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
332   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
333   N        -0.101  -0.109  -0.077  -0.099  -0.101  -0.051  -0.313  -0.319  -0.270
334   S        -0.753  -0.788  -0.771  -0.688  -0.735  -0.694  -0.693  -0.731  -0.698
335   M        -0.753  -0.727  -0.749  -0.888  -0.863  -0.858  -0.693  -0.660  -0.672
336   S        -0.753  -0.688  -0.742  -1.087  -0.993  -1.069  -0.693  -0.613  -0.664
337   N        -0.753  -0.775  -0.761  -0.668  -0.703  -0.688  -0.693  -0.717  -0.686
338   K        -0.753  -0.788  -0.771  -0.665  -0.714  -0.677  -0.693  -0.731  -0.698
339   I        -0.753  -0.754  -0.747  -0.842  -0.845  -0.857  -0.693  -0.692  -0.671
340   D        -0.753  -0.734  -0.741  -0.688  -0.653  -0.675  -0.693  -0.668  -0.664
341   D         0.144   0.135   0.079   0.192   0.175   0.091   0.067   0.051  -0.029
342   F        -0.753  -0.734  -0.741  -0.700  -0.660  -0.698  -0.693  -0.668  -0.664
343   V        -0.753  -0.734  -0.741  -0.490  -0.458  -0.459  -0.693  -0.668  -0.664
344   H        -0.753  -0.727  -0.749  -0.608  -0.580  -0.588  -0.693  -0.660  -0.672
345   R         1.201   1.268   1.136   1.246   1.339   1.161   1.205   1.320   1.070
346   P        -0.753  -0.775  -0.761  -0.579  -0.622  -0.588  -0.693  -0.717  -0.686
347   S        -1.404  -1.399  -1.367  -1.223  -1.195  -1.160  -1.072  -1.064  -1.012
348   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
349   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
350   -        -0.066  -0.049  -0.052  -0.117  -0.092  -0.101  -0.242  -0.217  -0.223
351   N        -0.753  -0.747  -0.739  -0.820  -0.817  -0.798  -0.693  -0.684  -0.661
352   N        -0.753  -0.782  -0.763  -0.681  -0.730  -0.692  -0.693  -0.724  -0.688
353   L         0.144   0.156   0.083  -0.184  -0.165  -0.281   0.067   0.085  -0.024
354   E        -0.753  -0.688  -0.742  -0.749  -0.651  -0.730  -0.693  -0.613  -0.664
355   Q        -0.753  -0.720  -0.735  -0.579  -0.523  -0.545  -0.693  -0.652  -0.656
356   R         1.201   1.141   1.109   1.438   1.348   1.291   1.205   1.097   1.020
357   D        -0.753  -0.788  -0.771  -0.635  -0.684  -0.666  -0.693  -0.731  -0.698
358   P         2.377   2.399   2.483   2.608   2.640   2.782   2.724   2.762   2.914
359   Q        -1.404  -1.399  -1.367  -1.370  -1.394  -1.311  -1.072  -1.064  -1.012
360   F         0.796   0.781   0.837   0.829   0.795   0.885   0.446   0.408   0.484
361   R        -0.753  -0.782  -0.763  -0.684  -0.739  -0.725  -0.693  -0.724  -0.688
362   E         1.201   1.141   1.109   1.248   1.159   1.111   1.205   1.097   1.020
363   Q        -1.404  -1.399  -1.367  -1.156  -1.145  -1.091  -1.072  -1.064  -1.012
364   G         0.796   0.781   0.837   0.847   0.813   0.902   0.446   0.408   0.484
365   N        -0.753  -0.788  -0.771  -0.954  -1.041  -1.022  -0.693  -0.731  -0.698
366   V        -0.101  -0.129  -0.081  -0.359  -0.386  -0.315  -0.313  -0.343  -0.275
367   V        -0.101  -0.108  -0.072  -0.121  -0.129  -0.068  -0.313  -0.318  -0.264
368   M        -1.404  -1.399  -1.367  -1.197  -1.195  -1.133  -1.072  -1.064  -1.012
369   S        -0.753  -0.788  -0.771  -0.690  -0.726  -0.696  -0.693  -0.731  -0.698
370   L         0.144   0.156   0.083  -0.147  -0.129  -0.236   0.067   0.085  -0.024
371   Y        -0.753  -0.688  -0.742  -0.795  -0.696  -0.780  -0.693  -0.613  -0.664
372   N        -0.101  -0.129  -0.072  -0.150  -0.182  -0.094  -0.313  -0.344  -0.265
373   L        -1.404  -1.399  -1.367  -1.287  -1.254  -1.226  -1.072  -1.064  -1.012
374   A        -0.101  -0.068  -0.073  -0.432  -0.398  -0.386  -0.313  -0.272  -0.266
375   C        -0.753  -0.688  -0.742  -0.440  -0.338  -0.415  -0.693  -0.613  -0.664
376   K        -0.880  -0.873  -0.833  -0.862  -0.845  -0.789  -0.835  -0.825  -0.767
377   Y        -0.204  -0.194  -0.145  -0.214  -0.210  -0.122  -0.439  -0.425  -0.358
378   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
379   I        -0.101  -0.064  -0.073  -0.121  -0.065  -0.071  -0.313  -0.265  -0.266
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P50110
Output conservation file - output/P50110
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
