1     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
2     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    M         1.271   1.281   1.369   1.447   1.459   1.593   1.376   1.391   1.528
17    S        -0.470  -0.518  -0.429  -0.571  -0.645  -0.516  -0.702  -0.765  -0.632
18    T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
19    D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
20    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
21    T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
22    R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
23    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
24    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
25    Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
26    P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
27    I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
28    Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
29    I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
30    E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
31    K        -1.003  -0.969  -0.900  -0.987  -0.935  -0.857  -1.069  -1.037  -0.907
32    A        -0.279  -0.329  -0.372  -0.199  -0.288  -0.339  -0.431  -0.518  -0.554
33    S        -0.818  -0.729  -0.851  -0.661  -0.531  -0.698  -0.856  -0.750  -0.855
34    N        -0.818  -0.736  -0.849  -0.827  -0.712  -0.873  -0.856  -0.761  -0.849
35    D        -1.302  -1.361  -1.280  -1.205  -1.271  -1.124  -1.175  -1.223  -1.085
36    P        -1.414  -1.422  -1.284  -1.371  -1.369  -1.186  -1.281  -1.280  -1.089
37    T        -0.891  -0.909  -0.880  -0.920  -0.940  -0.916  -0.962  -0.975  -0.887
38    L        -0.592  -0.567  -0.444  -0.807  -0.753  -0.577  -0.856  -0.822  -0.650
39    L        -0.891  -0.844  -0.863  -1.046  -0.996  -0.940  -0.962  -0.913  -0.871
40    L        -0.592  -0.575  -0.439  -0.780  -0.755  -0.544  -0.856  -0.834  -0.644
41    N         1.271   1.281   1.369   1.214   1.225   1.370   1.376   1.391   1.528
42    H         1.271   1.281   1.369   1.375   1.391   1.524   1.376   1.391   1.528
43    T         0.622   0.570   0.389   0.775   0.712   0.436   0.632   0.551   0.212
44    C         0.132   0.109   0.221   0.204   0.164   0.317  -0.218  -0.269  -0.108
45    L        -0.279  -0.313  -0.374  -0.360  -0.430  -0.502  -0.431  -0.500  -0.557
46    R         1.271   1.281   1.369   1.400   1.413   1.548   1.376   1.391   1.528
47    V         0.078   0.090   0.215  -0.093  -0.071   0.120  -0.325  -0.306  -0.120
48    K         1.271   1.281   1.369   1.118   1.131   1.279   1.376   1.391   1.528
49    D         1.271   1.281   1.369   1.240   1.248   1.395   1.376   1.391   1.528
50    P         0.622   0.538   0.391   0.782   0.677   0.424   0.632   0.500   0.215
51    A        -0.279  -0.298  -0.355  -0.418  -0.434  -0.524  -0.431  -0.440  -0.526
52    R        -0.818  -0.831  -0.864  -0.786  -0.834  -0.886  -0.856  -0.876  -0.869
53    T         0.303   0.360   0.299   0.276   0.370   0.247   0.101   0.199   0.042
54    V        -0.407  -0.450  -0.394  -0.463  -0.515  -0.442  -0.643  -0.681  -0.588
55    K        -0.407  -0.390  -0.389  -0.532  -0.526  -0.496  -0.643  -0.631  -0.584
56    F         1.271   1.281   1.369   1.251   1.267   1.406   1.376   1.391   1.528
57    Y         1.271   1.281   1.369   1.344   1.361   1.495   1.376   1.391   1.528
58    T        -0.375  -0.352  -0.383  -0.320  -0.279  -0.353  -0.568  -0.527  -0.567
59    E         0.303   0.344   0.274   0.103   0.170   0.003   0.101   0.171  -0.005
60    H        -1.600  -1.638  -1.573  -1.324  -1.388  -1.337  -1.281  -1.313  -1.189
61    F         0.303   0.282   0.261   0.196   0.156   0.071   0.101   0.059  -0.031
62    G         1.271   1.281   1.369   1.176   1.185   1.334   1.376   1.391   1.528
63    M         1.271   1.281   1.369   1.449   1.473   1.595   1.376   1.391   1.528
64    K         0.004  -0.000  -0.289  -0.022  -0.027  -0.457  -0.006  -0.014  -0.428
65    L         0.622   0.641   0.398   0.621   0.640   0.322   0.632   0.660   0.228
66    L         0.132   0.125   0.225  -0.121  -0.136   0.019  -0.218  -0.236  -0.102
67    S        -1.713  -1.681  -1.589  -1.703  -1.671  -1.554  -1.387  -1.359  -1.203
68    R        -1.414  -1.414  -1.284  -1.317  -1.313  -1.106  -1.281  -1.276  -1.089
69    K        -1.302  -1.305  -1.245  -1.326  -1.307  -1.197  -1.175  -1.170  -1.053
70    D        -1.414  -1.451  -1.291  -1.449  -1.483  -1.258  -1.281  -1.302  -1.095
71    F         1.271   1.281   1.369   1.251   1.267   1.406   1.376   1.391   1.528
72    E        -0.407  -0.385  -0.382  -0.497  -0.470  -0.444  -0.643  -0.621  -0.575
73    E        -0.407  -0.380  -0.391  -0.588  -0.552  -0.510  -0.643  -0.605  -0.584
74    A        -1.397  -1.425  -1.281  -1.259  -1.298  -1.117  -1.262  -1.279  -1.086
75    K         0.565   0.506   0.375   0.467   0.383   0.176   0.543   0.447   0.186
76    F         1.271   1.281   1.369   1.251   1.267   1.406   1.376   1.391   1.528
77    S        -0.592  -0.575  -0.441  -0.769  -0.745  -0.539  -0.856  -0.834  -0.646
78    L         0.622   0.641   0.398   0.618   0.639   0.314   0.632   0.660   0.228
79    Y         0.004  -0.029  -0.287   0.216   0.173  -0.228  -0.006  -0.057  -0.426
80    F        -0.279  -0.246  -0.356  -0.221  -0.167  -0.317  -0.431  -0.383  -0.528
81    L         1.271   1.281   1.369   1.178   1.187   1.336   1.376   1.391   1.528
82    S        -0.891  -0.896  -0.875  -0.925  -0.925  -0.902  -0.962  -0.961  -0.882
83    F         0.078   0.087   0.215  -0.132  -0.113   0.083  -0.325  -0.310  -0.121
84    P        -0.407  -0.354  -0.384  -0.512  -0.435  -0.470  -0.643  -0.568  -0.572
85    K        -1.713  -1.738  -1.591  -1.711  -1.746  -1.501  -1.387  -1.400  -1.204
86    D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
87    D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
88    I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
89    P        -0.223  -0.155  -0.344  -0.083   0.018  -0.299  -0.325  -0.228  -0.507
90    K        -0.928  -0.838  -0.874  -1.175  -1.018  -1.091  -0.984  -0.873  -0.877
91    N        -1.302  -1.291  -1.273  -1.296  -1.284  -1.257  -1.175  -1.169  -1.079
92    K        -2.011  -2.015  -1.859  -1.861  -1.869  -1.663  -1.494  -1.492  -1.291
93    N        -1.116  -1.090  -1.216  -0.947  -0.912  -1.095  -0.962  -0.934  -1.024
94    G        -1.600  -1.648  -1.585  -1.499  -1.564  -1.482  -1.281  -1.321  -1.199
95    E        -1.600  -1.493  -1.565  -1.544  -1.383  -1.516  -1.281  -1.179  -1.183
96    P        -2.011  -1.959  -1.847  -1.825  -1.739  -1.616  -1.494  -1.451  -1.284
97    D        -1.302  -1.338  -1.270  -1.297  -1.365  -1.250  -1.175  -1.206  -1.077
98    V        -0.818  -0.902  -0.873  -0.623  -0.740  -0.707  -0.856  -0.941  -0.875
99    F        -0.592  -0.589  -0.454  -0.695  -0.676  -0.469  -0.856  -0.850  -0.663
100   S        -1.414  -1.420  -1.293  -1.409  -1.430  -1.230  -1.281  -1.279  -1.096
101   A        -0.577  -0.460  -0.804  -0.272  -0.113  -0.644  -0.537  -0.391  -0.794
102   H        -1.116  -1.006  -1.215  -0.966  -0.816  -1.098  -0.962  -0.841  -1.023
103   G         1.271   1.281   1.369   1.176   1.185   1.334   1.376   1.391   1.528
104   V        -0.407  -0.443  -0.391  -0.463  -0.513  -0.439  -0.643  -0.682  -0.586
105   L         0.622   0.570   0.389   0.618   0.551   0.299   0.632   0.551   0.212
106   E         1.271   1.281   1.369   1.176   1.188   1.334   1.376   1.391   1.528
107   L         1.271   1.281   1.369   1.178   1.187   1.336   1.376   1.391   1.528
108   T         0.303   0.331   0.300   0.376   0.419   0.361   0.101   0.148   0.045
109   H         0.622   0.538   0.391   0.818   0.716   0.492   0.632   0.500   0.215
110   N         1.271   1.281   1.369   1.214   1.225   1.370   1.376   1.391   1.528
111   W        -1.003  -1.014  -0.901  -0.870  -0.881  -0.726  -1.069  -1.067  -0.907
112   G         1.271   1.281   1.369   1.176   1.185   1.334   1.376   1.391   1.528
113   T        -0.279  -0.214  -0.352  -0.193  -0.101  -0.311  -0.431  -0.344  -0.521
114   E         1.271   1.281   1.369   1.176   1.188   1.334   1.376   1.391   1.528
115   K        -0.519  -0.538  -0.442  -0.764  -0.802  -0.674  -0.750  -0.776  -0.646
116   N         0.004  -0.023  -0.285   0.079   0.027  -0.385  -0.006  -0.049  -0.422
117   P        -1.003  -0.984  -0.905  -1.032  -1.009  -0.898  -1.069  -1.049  -0.914
118   D        -1.302  -1.298  -1.257  -1.318  -1.317  -1.248  -1.175  -1.163  -1.064
119   Y         0.004  -0.029  -0.287   0.230   0.190  -0.200  -0.006  -0.057  -0.426
120   K         0.004  -0.064  -0.288   0.016  -0.074  -0.375  -0.006  -0.103  -0.427
121   I        -0.818  -0.841  -0.864  -0.757  -0.780  -0.817  -0.856  -0.877  -0.865
122   N         0.004  -0.029  -0.287   0.130   0.080  -0.251  -0.006  -0.057  -0.426
123   N         1.271   1.281   1.369   1.214   1.225   1.370   1.376   1.391   1.528
124   G         1.271   1.281   1.369   1.176   1.185   1.334   1.376   1.391   1.528
125   N         1.271   1.281   1.369   1.214   1.225   1.370   1.376   1.391   1.528
126   E        -1.003  -1.045  -0.916  -1.149  -1.197  -0.986  -1.069  -1.103  -0.923
127   E         1.271   1.281   1.369   1.176   1.188   1.334   1.376   1.391   1.528
128   P         0.303   0.331   0.300   0.284   0.339   0.223   0.101   0.148   0.045
129   H        -0.577  -0.617  -0.821  -0.338  -0.404  -0.774  -0.537  -0.588  -0.814
130   R         1.271   1.281   1.369   1.400   1.413   1.548   1.376   1.391   1.528
131   G         1.271   1.281   1.369   1.176   1.185   1.334   1.376   1.391   1.528
132   F         1.271   1.281   1.369   1.251   1.267   1.406   1.376   1.391   1.528
133   G         1.271   1.281   1.369   1.176   1.185   1.334   1.376   1.391   1.528
134   H         1.271   1.281   1.369   1.375   1.391   1.524   1.376   1.391   1.528
135   I         0.622   0.570   0.389   0.757   0.700   0.432   0.632   0.551   0.212
136   C         1.271   1.281   1.369   1.473   1.488   1.618   1.376   1.391   1.528
137   F        -0.577  -0.591  -0.817  -0.364  -0.380  -0.690  -0.537  -0.554  -0.810
138   S         0.622   0.538   0.391   0.724   0.625   0.405   0.632   0.500   0.215
139   V         0.622   0.678   0.399   0.780   0.847   0.471   0.632   0.716   0.231
140   S        -0.279  -0.190  -0.358  -0.302  -0.173  -0.418  -0.431  -0.304  -0.531
141   D         0.303   0.371   0.303   0.179   0.284   0.152   0.101   0.218   0.051
142   I         0.303   0.292   0.265   0.256   0.240   0.133   0.101   0.078  -0.022
143   N        -0.279  -0.272  -0.355  -0.365  -0.334  -0.453  -0.431  -0.405  -0.525
144   K        -0.279  -0.317  -0.364  -0.297  -0.332  -0.466  -0.431  -0.469  -0.543
145   T        -1.116  -1.022  -1.195  -0.880  -0.744  -1.030  -0.962  -0.859  -1.004
146   C        -0.577  -0.533  -0.810  -0.191  -0.128  -0.577  -0.537  -0.481  -0.802
147   E        -1.302  -1.265  -1.252  -1.218  -1.143  -1.133  -1.175  -1.133  -1.060
148   E        -1.713  -1.692  -1.590  -1.488  -1.447  -1.357  -1.387  -1.368  -1.203
149   L         0.622   0.640   0.400   0.609   0.628   0.296   0.632   0.659   0.233
150   E         0.303   0.331   0.300   0.122   0.165   0.085   0.101   0.148   0.045
151   S        -1.116  -1.092  -1.212  -0.966  -0.930  -1.165  -0.962  -0.936  -1.020
152   Q        -2.011  -1.959  -1.847  -1.965  -1.893  -1.722  -1.494  -1.451  -1.284
153   G         0.622   0.657   0.402   0.596   0.636   0.271   0.632   0.684   0.235
154   V         0.622   0.570   0.389   0.780   0.714   0.454   0.632   0.551   0.212
155   K         0.303   0.283   0.263   0.100   0.066   0.015   0.101   0.061  -0.027
156   F         1.271   1.281   1.369   1.251   1.267   1.406   1.376   1.391   1.528
157   K         0.078   0.087   0.215  -0.164  -0.145   0.053  -0.325  -0.310  -0.121
158   K         1.271   1.281   1.369   1.118   1.131   1.279   1.376   1.391   1.528
159   R         0.132   0.179   0.245  -0.126  -0.054   0.053  -0.218  -0.132  -0.063
160   L         1.271   1.281   1.369   1.178   1.187   1.336   1.376   1.391   1.528
161   S         0.132   0.165   0.236  -0.017   0.045   0.134  -0.218  -0.159  -0.080
162   E         0.622   0.685   0.402   0.659   0.734   0.331   0.632   0.726   0.236
163   G         1.271   1.281   1.369   1.176   1.185   1.334   1.376   1.391   1.528
164   R         0.004  -0.046  -0.288   0.250   0.174  -0.226  -0.006  -0.079  -0.427
165   Q         0.132   0.115   0.221   0.166   0.141   0.283  -0.218  -0.256  -0.109
166   K         0.622   0.660   0.401   0.571   0.617   0.294   0.632   0.689   0.233
167   D        -0.592  -0.606  -0.457  -0.798  -0.813  -0.581  -0.856  -0.871  -0.666
168   I         1.271   1.281   1.369   1.314   1.334   1.466   1.376   1.391   1.528
169   A         1.271   1.281   1.369   1.315   1.331   1.468   1.376   1.391   1.528
170   F         1.271   1.281   1.369   1.251   1.267   1.406   1.376   1.391   1.528
171   A         1.271   1.281   1.369   1.315   1.331   1.468   1.376   1.391   1.528
172   L         1.271   1.281   1.369   1.178   1.187   1.336   1.376   1.391   1.528
173   G         0.622   0.685   0.402   0.659   0.733   0.331   0.632   0.726   0.236
174   P         1.271   1.281   1.369   1.362   1.383   1.512   1.376   1.391   1.528
175   D         0.303   0.333   0.275   0.196   0.239   0.108   0.101   0.152  -0.003
176   G         0.622   0.538   0.391   0.601   0.487   0.265   0.632   0.500   0.215
177   Y         1.271   1.281   1.369   1.344   1.361   1.495   1.376   1.391   1.528
178   W         1.271   1.281   1.369   1.486   1.499   1.631   1.376   1.391   1.528
179   I         0.622   0.570   0.389   0.756   0.699   0.431   0.632   0.551   0.212
180   E         1.271   1.281   1.369   1.176   1.188   1.334   1.376   1.391   1.528
181   L         0.622   0.570   0.389   0.618   0.551   0.299   0.632   0.551   0.212
182   I         0.622   0.538   0.391   0.756   0.658   0.434   0.632   0.500   0.215
183   T        -1.713  -1.724  -1.592  -1.558  -1.588  -1.362  -1.387  -1.391  -1.204
184   Y        -1.302  -1.348  -1.257  -1.140  -1.184  -1.032  -1.175  -1.208  -1.064
185   S        -1.713  -1.691  -1.589  -1.716  -1.691  -1.534  -1.387  -1.367  -1.203
186   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
187   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
188   R        -0.818  -0.745  -0.854  -0.766  -0.663  -0.779  -0.856  -0.761  -0.854
189   E        -1.269  -1.261  -1.261  -1.262  -1.249  -1.265  -1.123  -1.114  -1.067
190   G        -0.715  -0.692  -0.841  -0.775  -0.742  -0.980  -0.706  -0.678  -0.838
191   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
192   Q        -1.416  -1.407  -1.288  -1.292  -1.295  -1.123  -1.269  -1.258  -1.090
193   E        -1.023  -1.036  -0.913  -1.049  -1.078  -0.908  -1.073  -1.087  -0.917
194   Y        -1.416  -1.432  -1.288  -1.440  -1.462  -1.257  -1.269  -1.281  -1.090
195   P        -1.003  -0.964  -0.905  -1.197  -1.149  -1.033  -1.069  -1.025  -0.912
196   K        -0.818  -0.816  -0.862  -0.802  -0.775  -0.894  -0.856  -0.842  -0.863
197   G        -1.414  -1.363  -1.280  -1.611  -1.540  -1.417  -1.281  -1.238  -1.086
198   S        -2.011  -2.010  -1.850  -1.829  -1.831  -1.614  -1.494  -1.489  -1.286
199   V        -1.302  -1.281  -1.254  -1.234  -1.202  -1.183  -1.175  -1.146  -1.061
200   G        -1.414  -1.417  -1.284  -1.449  -1.444  -1.226  -1.281  -1.276  -1.089
201   N        -0.577  -0.562  -0.807  -0.343  -0.324  -0.724  -0.537  -0.523  -0.797
202   K         0.078   0.091   0.217  -0.186  -0.151   0.043  -0.325  -0.303  -0.117
203   F        -0.279  -0.304  -0.362  -0.303  -0.322  -0.412  -0.431  -0.456  -0.536
204   N         1.271   1.281   1.369   1.214   1.225   1.370   1.376   1.391   1.528
205   H         1.271   1.281   1.369   1.375   1.391   1.524   1.376   1.391   1.528
206   T         1.271   1.281   1.369   1.341   1.355   1.491   1.376   1.391   1.528
207   M         1.271   1.281   1.369   1.449   1.473   1.595   1.376   1.391   1.528
208   I        -0.592  -0.592  -0.452  -0.754  -0.757  -0.554  -0.856  -0.853  -0.660
209   R         1.271   1.281   1.369   1.400   1.413   1.548   1.376   1.391   1.528
210   I         0.622   0.685   0.402   0.776   0.851   0.465   0.632   0.726   0.236
211   K         1.271   1.281   1.369   1.118   1.131   1.279   1.376   1.391   1.528
212   N         0.622   0.685   0.402   0.665   0.738   0.343   0.632   0.726   0.236
213   P         0.622   0.570   0.389   0.782   0.721   0.420   0.632   0.551   0.212
214   T        -0.818  -0.799  -0.861  -0.944  -0.951  -0.982  -0.856  -0.854  -0.865
215   R        -0.577  -0.562  -0.807  -0.499  -0.482  -0.789  -0.537  -0.523  -0.797
216   S         1.271   1.281   1.369   1.281   1.300   1.434   1.376   1.391   1.528
217   L         0.303   0.264   0.269   0.169   0.102   0.094   0.101   0.027  -0.015
218   E        -0.577  -0.686  -0.814  -0.523  -0.685  -0.903  -0.537  -0.671  -0.805
219   F         1.271   1.281   1.369   1.251   1.267   1.406   1.376   1.391   1.528
220   Y         1.271   1.281   1.369   1.344   1.361   1.495   1.376   1.391   1.528
221   Q        -0.375  -0.367  -0.393  -0.233  -0.218  -0.271  -0.568  -0.552  -0.580
222   N        -0.407  -0.395  -0.398  -0.637  -0.641  -0.605  -0.643  -0.638  -0.595
223   V         0.303   0.264   0.269   0.260   0.182   0.131   0.101   0.027  -0.015
224   L         0.622   0.570   0.389   0.638   0.575   0.348   0.632   0.551   0.212
225   G         1.271   1.281   1.369   1.176   1.185   1.334   1.376   1.391   1.528
226   M         0.622   0.657   0.402   0.879   0.934   0.546   0.632   0.684   0.235
227   K         0.622   0.641   0.398   0.571   0.594   0.289   0.632   0.660   0.228
228   L         0.004  -0.046  -0.288   0.071   0.001  -0.332  -0.006  -0.079  -0.427
229   L        -0.818  -0.907  -0.870  -0.855  -0.975  -0.911  -0.856  -0.948  -0.875
230   R        -0.519  -0.521  -0.430  -0.551  -0.562  -0.457  -0.750  -0.754  -0.631
231   T         0.004  -0.046  -0.288   0.201   0.124  -0.259  -0.006  -0.079  -0.427
232   S         0.004  -0.126  -0.302   0.180   0.015  -0.252  -0.006  -0.188  -0.447
233   E        -0.818  -0.819  -0.856  -0.907  -0.926  -0.971  -0.856  -0.864  -0.860
234   H         0.622   0.570   0.389   0.814   0.753   0.479   0.632   0.551   0.212
235   E        -0.577  -0.670  -0.817  -0.505  -0.638  -0.874  -0.537  -0.652  -0.809
236   S        -1.302  -1.261  -1.256  -1.354  -1.302  -1.278  -1.175  -1.133  -1.063
237   A         0.622   0.538   0.391   0.735   0.626   0.381   0.632   0.500   0.215
238   K         0.622   0.570   0.389   0.538   0.469   0.195   0.632   0.551   0.212
239   F         1.271   1.281   1.369   1.251   1.267   1.406   1.376   1.391   1.528
240   T         0.622   0.570   0.389   0.766   0.699   0.413   0.632   0.551   0.212
241   L         0.622   0.538   0.391   0.603   0.489   0.267   0.632   0.500   0.215
242   Y         1.271   1.281   1.369   1.344   1.361   1.495   1.376   1.391   1.528
243   F         1.271   1.281   1.369   1.251   1.267   1.406   1.376   1.391   1.528
244   L         1.271   1.281   1.369   1.178   1.187   1.336   1.376   1.391   1.528
245   G         0.004  -0.063  -0.294   0.060  -0.033  -0.362  -0.006  -0.102  -0.435
246   Y         1.271   1.281   1.369   1.344   1.361   1.495   1.376   1.391   1.528
247   G        -1.414  -1.416  -1.281  -1.574  -1.567  -1.366  -1.281  -1.277  -1.087
248   V        -1.713  -1.736  -1.602  -1.573  -1.614  -1.458  -1.387  -1.399  -1.212
249   -         0.495   0.474   0.348   0.474   0.443   0.219   0.431   0.395   0.135
250   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
251   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
252   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
253   P        -1.416  -1.408  -1.302  -1.447  -1.439  -1.253  -1.269  -1.259  -1.103
254   K        -1.416  -1.417  -1.297  -1.505  -1.510  -1.315  -1.269  -1.268  -1.099
255   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
256   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
257   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
258   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
259   T        -1.738  -1.731  -1.607  -1.620  -1.631  -1.483  -1.400  -1.391  -1.215
260   D        -1.269  -1.301  -1.262  -1.144  -1.187  -1.144  -1.123  -1.155  -1.067
261   S        -1.397  -1.369  -1.285  -1.423  -1.384  -1.227  -1.262  -1.233  -1.089
262   V        -1.713  -1.681  -1.589  -1.399  -1.352  -1.248  -1.387  -1.359  -1.203
263   F        -1.414  -1.427  -1.284  -1.424  -1.423  -1.212  -1.281  -1.284  -1.089
264   S        -0.592  -0.567  -0.444  -0.871  -0.830  -0.651  -0.856  -0.822  -0.650
265   C        -0.577  -0.477  -0.793  -0.246  -0.115  -0.578  -0.537  -0.413  -0.781
266   E         0.622   0.640   0.400   0.633   0.655   0.356   0.632   0.659   0.233
267   S         0.303   0.360   0.299   0.156   0.242   0.129   0.101   0.199   0.042
268   V        -0.407  -0.352  -0.385  -0.550  -0.477  -0.483  -0.643  -0.567  -0.576
269   L         0.303   0.331   0.300   0.169   0.210   0.149   0.101   0.148   0.045
270   E         1.271   1.281   1.369   1.176   1.188   1.334   1.376   1.391   1.528
271   L         1.271   1.281   1.369   1.178   1.187   1.336   1.376   1.391   1.528
272   T         1.271   1.281   1.369   1.341   1.355   1.491   1.376   1.391   1.528
273   H         0.622   0.570   0.389   0.838   0.781   0.537   0.632   0.551   0.212
274   N         1.271   1.281   1.369   1.214   1.225   1.370   1.376   1.391   1.528
275   W         0.622   0.570   0.389   0.928   0.865   0.589   0.632   0.551   0.212
276   G         1.271   1.281   1.369   1.176   1.185   1.334   1.376   1.391   1.528
277   T         1.271   1.281   1.369   1.341   1.355   1.491   1.376   1.391   1.528
278   E         1.271   1.281   1.369   1.176   1.188   1.334   1.376   1.391   1.528
279   N        -1.003  -1.005  -0.915  -1.207  -1.230  -1.078  -1.069  -1.071  -0.922
280   D         0.132   0.130   0.225  -0.140  -0.157  -0.020  -0.218  -0.227  -0.102
281   P        -1.302  -1.358  -1.259  -1.180  -1.259  -1.148  -1.175  -1.219  -1.067
282   N        -0.818  -0.859  -0.854  -0.885  -0.963  -0.971  -0.856  -0.901  -0.858
283   F         0.622   0.538   0.391   0.698   0.598   0.386   0.632   0.500   0.215
284   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
285   H        -1.713  -1.684  -1.595  -1.646  -1.599  -1.459  -1.387  -1.362  -1.206
286   Y         1.271   1.281   1.369   1.344   1.361   1.495   1.376   1.391   1.528
287   H         1.271   1.281   1.369   1.375   1.391   1.524   1.376   1.391   1.528
288   N         0.622   0.660   0.401   0.658   0.703   0.360   0.632   0.689   0.233
289   G         1.271   1.281   1.369   1.176   1.185   1.334   1.376   1.391   1.528
290   N         1.271   1.281   1.369   1.214   1.225   1.370   1.376   1.391   1.528
291   S        -0.891  -0.855  -0.868  -0.916  -0.871  -0.848  -0.962  -0.923  -0.876
292   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
293   E        -1.302  -1.341  -1.266  -1.287  -1.335  -1.227  -1.175  -1.206  -1.072
294   P         0.132   0.125   0.225  -0.031  -0.049   0.075  -0.218  -0.236  -0.102
295   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
296   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
297   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
298   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
299   Q         0.622   0.538   0.391   0.840   0.729   0.465   0.632   0.500   0.215
300   G         1.271   1.281   1.369   1.176   1.185   1.334   1.376   1.391   1.528
301   Y         0.132   0.134   0.226  -0.008  -0.007   0.110  -0.218  -0.220  -0.100
302   G         1.271   1.281   1.369   1.176   1.185   1.334   1.376   1.391   1.528
303   H         1.271   1.281   1.369   1.375   1.391   1.524   1.376   1.391   1.528
304   I        -0.818  -0.855  -0.869  -0.722  -0.764  -0.811  -0.856  -0.891  -0.871
305   C         0.622   0.641   0.398   0.911   0.938   0.582   0.632   0.660   0.228
306   I         0.078   0.087   0.215  -0.093  -0.076   0.120  -0.325  -0.310  -0.120
307   S         0.622   0.641   0.398   0.724   0.754   0.416   0.632   0.660   0.228
308   C        -0.407  -0.392  -0.400  -0.332  -0.332  -0.334  -0.643  -0.635  -0.597
309   D        -0.818  -0.755  -0.852  -0.905  -0.800  -0.974  -0.856  -0.776  -0.854
310   D         0.303   0.230   0.262   0.196   0.058   0.082   0.101  -0.036  -0.029
311   A        -0.407  -0.375  -0.397  -0.415  -0.380  -0.384  -0.643  -0.619  -0.593
312   G        -1.003  -1.039  -0.906  -1.157  -1.216  -1.025  -1.069  -1.097  -0.914
313   A        -0.407  -0.362  -0.387  -0.566  -0.488  -0.505  -0.643  -0.583  -0.579
314   L        -0.592  -0.567  -0.444  -0.827  -0.776  -0.596  -0.856  -0.822  -0.650
315   C         1.271   1.281   1.369   1.473   1.488   1.618   1.376   1.391   1.528
316   K        -1.713  -1.694  -1.584  -1.726  -1.698  -1.511  -1.387  -1.369  -1.199
317   E        -0.279  -0.369  -0.383  -0.353  -0.488  -0.520  -0.431  -0.550  -0.569
318   I        -0.519  -0.551  -0.446  -0.663  -0.724  -0.595  -0.750  -0.795  -0.652
319   E         0.303   0.322   0.273   0.134   0.162   0.049   0.101   0.132  -0.007
320   V        -1.713  -1.715  -1.593  -1.719  -1.734  -1.509  -1.387  -1.385  -1.205
321   K        -1.414  -1.379  -1.278  -1.594  -1.550  -1.364  -1.281  -1.249  -1.085
322   Y         0.112   0.114   0.225  -0.041  -0.038   0.115  -0.257  -0.258  -0.101
323   G         0.409   0.407   0.299   0.347   0.335   0.171   0.288   0.281   0.043
324   D         0.409   0.394   0.303   0.370   0.340   0.158   0.288   0.259   0.051
325   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
326   K        -0.375  -0.375  -0.388  -0.642  -0.658  -0.668  -0.568  -0.577  -0.575
327   I        -0.519  -0.551  -0.446  -0.626  -0.687  -0.552  -0.750  -0.795  -0.652
328   Q        -1.302  -1.361  -1.280  -1.159  -1.248  -1.172  -1.175  -1.223  -1.085
329   W         0.303   0.264   0.269   0.445   0.374   0.322   0.101   0.027  -0.015
330   S        -0.592  -0.563  -0.455  -0.863  -0.826  -0.646  -0.856  -0.817  -0.664
331   P        -0.891  -0.854  -0.883  -0.977  -0.939  -0.952  -0.962  -0.920  -0.889
332   K        -0.279  -0.312  -0.368  -0.342  -0.377  -0.426  -0.431  -0.468  -0.548
333   F        -0.592  -0.567  -0.444  -0.762  -0.734  -0.530  -0.856  -0.822  -0.650
334   N        -1.003  -1.005  -0.915  -1.127  -1.130  -0.994  -1.069  -1.071  -0.923
335   Q        -0.818  -0.843  -0.871  -0.712  -0.785  -0.866  -0.856  -0.898  -0.875
336   G         1.271   1.281   1.369   1.176   1.185   1.334   1.376   1.391   1.528
337   R        -0.592  -0.574  -0.452  -0.843  -0.799  -0.632  -0.856  -0.831  -0.660
338   M        -0.279  -0.214  -0.352  -0.119  -0.011  -0.268  -0.431  -0.344  -0.521
339   K         1.271   1.281   1.369   1.118   1.131   1.279   1.376   1.391   1.528
340   N        -1.116  -1.141  -1.234  -0.970  -1.015  -1.159  -0.962  -0.989  -1.041
341   I        -0.279  -0.303  -0.363  -0.266  -0.284  -0.416  -0.431  -0.453  -0.542
342   A         1.271   1.281   1.369   1.315   1.331   1.468   1.376   1.391   1.528
343   F         1.271   1.281   1.369   1.251   1.267   1.406   1.376   1.391   1.528
344   L        -0.407  -0.440  -0.395  -0.532  -0.572  -0.489  -0.643  -0.677  -0.590
345   K        -0.592  -0.567  -0.444  -0.894  -0.856  -0.653  -0.856  -0.822  -0.650
346   D         1.271   1.281   1.369   1.240   1.248   1.395   1.376   1.391   1.528
347   P         1.271   1.281   1.369   1.362   1.383   1.512   1.376   1.391   1.528
348   D         1.271   1.281   1.369   1.240   1.248   1.395   1.376   1.391   1.528
349   G         0.303   0.230   0.262   0.134  -0.001   0.028   0.101  -0.036  -0.029
350   Y         1.271   1.281   1.369   1.344   1.361   1.495   1.376   1.391   1.528
351   S         0.132   0.109   0.221   0.060   0.029   0.201  -0.218  -0.269  -0.108
352   I         0.622   0.538   0.391   0.756   0.658   0.434   0.632   0.500   0.215
353   E         1.271   1.281   1.369   1.176   1.188   1.334   1.376   1.391   1.528
354   V        -0.279  -0.304  -0.362  -0.223  -0.256  -0.380  -0.431  -0.456  -0.536
355   V        -0.407  -0.390  -0.395  -0.463  -0.445  -0.446  -0.643  -0.629  -0.591
356   P        -1.116  -1.189  -1.239  -0.861  -0.971  -1.108  -0.962  -1.040  -1.046
357   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
358   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
359   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
360   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
361   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
362   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
363   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
364   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
365   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
366   H        -1.738  -1.750  -1.606  -1.622  -1.659  -1.474  -1.400  -1.405  -1.214
367   G        -0.928  -0.941  -0.899  -0.911  -0.927  -0.824  -0.984  -0.999  -0.906
368   L        -0.458  -0.442  -0.411  -0.638  -0.610  -0.542  -0.706  -0.684  -0.609
369   I        -1.414  -1.420  -1.283  -1.498  -1.492  -1.292  -1.281  -1.279  -1.088
370   A        -2.011  -2.015  -1.859  -1.785  -1.816  -1.594  -1.494  -1.492  -1.291
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P50107
Output conservation file - output/P50107
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
