1     M         0.885   0.896   0.957   1.135   1.144   1.213   0.932   0.946   1.031
2     N        -0.378  -0.339  -0.241  -0.541  -0.476  -0.344  -0.738  -0.674  -0.536
3     R        -2.075  -1.941  -1.819  -2.040  -1.834  -1.655  -1.830  -1.700  -1.476
4     S        -2.075  -2.084  -1.828  -1.911  -1.914  -1.522  -1.830  -1.817  -1.483
5     P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     E        -1.554  -1.539  -1.427  -1.440  -1.405  -1.235  -1.540  -1.504  -1.311
8     F        -1.033  -1.082  -0.929  -0.822  -0.863  -0.657  -1.249  -1.282  -1.045
9     Q        -1.033  -0.983  -0.925  -1.180  -1.109  -0.991  -1.249  -1.185  -1.041
10    R        -1.762  -1.676  -1.442  -1.860  -1.709  -1.377  -1.740  -1.642  -1.326
11    Y        -0.975  -0.832  -0.909  -1.114  -0.949  -0.916  -1.183  -1.009  -1.023
12    A        -1.512  -1.608  -1.424  -1.638  -1.725  -1.433  -1.517  -1.581  -1.309
13    K        -1.100  -1.039  -0.931  -1.230  -1.134  -0.998  -1.294  -1.214  -1.047
14    A        -2.424  -2.429  -2.145  -2.381  -2.387  -1.966  -1.962  -1.941  -1.589
15    F        -1.318  -1.308  -1.406  -1.346  -1.355  -1.464  -1.249  -1.245  -1.290
16    Q        -1.033  -1.035  -0.922  -1.210  -1.190  -0.995  -1.249  -1.233  -1.037
17    K        -1.033  -0.930  -0.919  -1.221  -1.075  -1.009  -1.249  -1.132  -1.034
18    Q        -1.046  -1.086  -0.937  -1.257  -1.327  -1.115  -1.245  -1.281  -1.054
19    L        -2.075  -2.058  -1.826  -2.255  -2.204  -1.818  -1.830  -1.800  -1.482
20    S        -2.075  -1.991  -1.818  -2.124  -2.037  -1.716  -1.830  -1.743  -1.475
21    K        -1.175  -1.115  -0.940  -1.400  -1.309  -1.042  -1.394  -1.316  -1.059
22    V        -1.554  -1.530  -1.418  -1.791  -1.736  -1.540  -1.540  -1.495  -1.302
23    Q        -0.940  -0.930  -0.919  -1.026  -1.038  -1.017  -1.104  -1.106  -1.034
24    Q        -1.554  -1.562  -1.428  -1.584  -1.610  -1.397  -1.540  -1.541  -1.313
25    T        -1.554  -1.428  -1.423  -1.560  -1.425  -1.349  -1.540  -1.425  -1.309
26    G        -0.635  -0.654  -0.880  -0.566  -0.604  -0.989  -0.667  -0.693  -0.981
27    G         0.166   0.220  -0.151   0.245   0.311  -0.210   0.153   0.229  -0.375
28    R        -2.453  -2.447  -2.147  -2.314  -2.323  -1.864  -1.976  -1.952  -1.590
29    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
30    G        -1.762  -1.582  -1.788  -1.450  -1.200  -1.603  -1.517  -1.329  -1.451
31    Q        -1.968  -1.902  -1.802  -1.891  -1.811  -1.638  -1.740  -1.671  -1.463
32    V        -1.165  -0.960  -1.376  -0.990  -0.717  -1.331  -1.072  -0.832  -1.260
33    P        -1.512  -1.490  -1.418  -1.456  -1.436  -1.317  -1.517  -1.477  -1.304
34    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
35    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
36    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
37    S        -0.400  -0.403  -0.244  -0.549  -0.556  -0.300  -0.778  -0.792  -0.542
38    P         0.885   0.896   0.957   1.018   1.030   1.111   0.932   0.946   1.031
39    R        -0.772  -0.715  -0.902  -0.788  -0.707  -1.012  -0.849  -0.773  -1.010
40    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
41    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
42    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
43    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
44    G         0.102  -0.067  -0.167   0.190  -0.032  -0.170   0.059  -0.207  -0.404
45    A        -1.165  -1.197  -1.395  -1.167  -1.229  -1.535  -1.072  -1.108  -1.279
46    F         0.166   0.083  -0.165   0.394   0.285  -0.139   0.153   0.028  -0.401
47    A        -1.968  -2.049  -1.814  -2.003  -2.082  -1.713  -1.740  -1.788  -1.473
48    G        -0.189  -0.199  -0.227  -0.321  -0.350  -0.457  -0.404  -0.428  -0.512
49    L        -1.512  -1.567  -1.415  -1.701  -1.759  -1.495  -1.517  -1.548  -1.301
50    G         0.166   0.083  -0.165   0.253   0.149  -0.212   0.153   0.028  -0.401
51    G         0.166   0.004  -0.147   0.213  -0.017  -0.295   0.153  -0.093  -0.370
52    L        -0.520  -0.536  -0.873  -0.519  -0.542  -0.982  -0.515  -0.542  -0.972
53    L        -1.165  -1.187  -1.399  -1.168  -1.220  -1.516  -1.072  -1.098  -1.283
54    L        -0.834  -0.906  -0.899  -1.079  -1.183  -1.189  -0.960  -1.034  -1.008
55    L         0.885   0.896   0.957   0.707   0.719   0.841   0.932   0.946   1.031
56    G        -0.520  -0.463  -0.869  -0.411  -0.341  -0.982  -0.515  -0.443  -0.967
57    G        -1.165  -1.198  -1.383  -1.058  -1.142  -1.479  -1.072  -1.122  -1.267
58    G        -0.975  -0.921  -0.913  -1.240  -1.188  -1.121  -1.183  -1.127  -1.028
59    A        -1.100  -1.080  -0.929  -1.346  -1.328  -1.061  -1.294  -1.269  -1.045
60    L        -2.093  -2.060  -1.823  -1.919  -1.827  -1.519  -1.851  -1.798  -1.479
61    F        -1.968  -2.046  -1.815  -1.923  -2.081  -1.753  -1.740  -1.786  -1.473
62    I        -1.968  -1.982  -1.806  -2.053  -2.111  -1.816  -1.740  -1.737  -1.467
63    N        -0.975  -1.020  -0.918  -1.046  -1.101  -0.933  -1.183  -1.221  -1.033
64    N        -1.165  -1.248  -1.389  -0.882  -1.010  -1.225  -1.072  -1.174  -1.273
65    A        -0.438  -0.388  -0.241  -0.819  -0.706  -0.471  -0.849  -0.764  -0.537
66    L         0.885   0.896   0.957   0.707   0.719   0.841   0.932   0.946   1.031
67    F         0.885   0.896   0.957   1.023   1.038   1.116   0.932   0.946   1.031
68    N         0.885   0.896   0.957   0.933   0.947   1.038   0.932   0.946   1.031
69    V         0.885   0.896   0.957   0.783   0.808   0.907   0.932   0.946   1.031
70    D         0.885   0.896   0.957   0.971   0.987   1.070   0.932   0.946   1.031
71    G         0.885   0.896   0.957   0.864   0.878   0.978   0.932   0.946   1.031
72    G         0.885   0.896   0.957   0.864   0.878   0.978   0.932   0.946   1.031
73    H        -0.834  -0.772  -0.898  -0.554  -0.453  -0.731  -0.960  -0.866  -1.006
74    R         0.885   0.896   0.957   0.819   0.837   0.938   0.932   0.946   1.031
75    A         0.885   0.896   0.957   0.726   0.741   0.857   0.932   0.946   1.031
76    I         0.885   0.896   0.957   0.858   0.875   0.972   0.932   0.946   1.031
77    V        -1.431  -1.451  -1.417  -1.467  -1.514  -1.406  -1.406  -1.442  -1.302
78    Y         0.885   0.896   0.957   1.099   1.109   1.181   0.932   0.946   1.031
79    S        -0.520  -0.600  -0.882  -0.352  -0.461  -0.914  -0.515  -0.622  -0.984
80    R         0.885   0.896   0.957   0.819   0.837   0.938   0.932   0.946   1.031
81    I        -0.520  -0.554  -0.875  -0.434  -0.483  -1.037  -0.515  -0.564  -0.975
82    H        -1.637  -1.544  -1.428  -1.539  -1.436  -1.215  -1.628  -1.523  -1.313
83    G         0.885   0.896   0.957   0.864   0.878   0.978   0.932   0.946   1.031
84    V        -0.189  -0.272  -0.220  -0.358  -0.497  -0.432  -0.404  -0.554  -0.499
85    S        -0.975  -1.043  -0.912  -1.079  -1.148  -0.951  -1.183  -1.233  -1.025
86    S        -1.968  -1.973  -1.805  -1.755  -1.767  -1.548  -1.740  -1.728  -1.466
87    R        -1.512  -1.611  -1.417  -1.623  -1.769  -1.456  -1.517  -1.585  -1.303
88    I         0.885   0.896   0.957   0.858   0.875   0.972   0.932   0.946   1.031
89    F        -0.189  -0.033  -0.187  -0.001   0.228  -0.056  -0.404  -0.151  -0.440
90    N        -1.165  -1.030  -1.386  -0.816  -0.656  -1.213  -1.072  -0.925  -1.270
91    E         0.885   0.896   0.957   0.960   0.970   1.061   0.932   0.946   1.031
92    G         0.885   0.896   0.957   0.864   0.878   0.978   0.932   0.946   1.031
93    T         0.885   0.896   0.957   0.986   0.998   1.083   0.932   0.946   1.031
94    H         0.885   0.896   0.957   1.175   1.183   1.248   0.932   0.946   1.031
95    F        -0.834  -0.844  -0.908  -0.747  -0.754  -0.952  -0.960  -0.954  -1.020
96    I        -1.968  -2.048  -1.822  -2.002  -2.126  -1.783  -1.740  -1.787  -1.478
97    F         0.166   0.295  -0.148   0.251   0.403  -0.173   0.153   0.332  -0.370
98    P         0.885   0.896   0.957   1.030   1.043   1.121   0.932   0.946   1.031
99    W         0.885   0.896   0.957   1.190   1.200   1.261   0.932   0.946   1.031
100   L        -1.431  -1.312  -1.402  -1.340  -1.187  -1.383  -1.406  -1.291  -1.289
101   D        -0.975  -0.846  -0.910  -1.009  -0.837  -0.874  -1.183  -1.033  -1.023
102   T        -1.431  -1.334  -1.408  -1.316  -1.166  -1.304  -1.406  -1.286  -1.293
103   P         0.166   0.004  -0.147   0.381   0.152  -0.154   0.153  -0.093  -0.370
104   I         0.166   0.232  -0.153   0.217   0.304  -0.280   0.153   0.245  -0.379
105   I        -1.512  -1.611  -1.413  -1.598  -1.690  -1.372  -1.517  -1.585  -1.300
106   Y         0.885   0.896   0.957   1.099   1.109   1.181   0.932   0.946   1.031
107   D         0.885   0.896   0.957   0.971   0.987   1.070   0.932   0.946   1.031
108   V         0.885   0.896   0.957   0.783   0.808   0.907   0.932   0.946   1.031
109   R         0.885   0.896   0.957   0.819   0.837   0.938   0.932   0.946   1.031
110   A         0.885   0.896   0.957   0.726   0.741   0.857   0.932   0.946   1.031
111   K         0.885   0.896   0.957   0.884   0.898   0.995   0.932   0.946   1.031
112   P         0.885   0.896   0.957   1.030   1.043   1.121   0.932   0.946   1.031
113   R         0.166   0.220  -0.151   0.193   0.263  -0.266   0.153   0.229  -0.375
114   N         0.166   0.220  -0.151   0.318   0.383  -0.145   0.153   0.229  -0.375
115   V        -0.189  -0.250  -0.219  -0.358  -0.459  -0.430  -0.404  -0.516  -0.497
116   A        -0.378  -0.401  -0.244  -0.725  -0.764  -0.486  -0.738  -0.787  -0.541
117   S         0.885   0.896   0.957   0.896   0.914   1.005   0.932   0.946   1.031
118   L         0.885   0.896   0.957   0.707   0.719   0.841   0.932   0.946   1.031
119   T         0.885   0.896   0.957   0.986   0.998   1.083   0.932   0.946   1.031
120   G         0.885   0.896   0.957   0.864   0.878   0.978   0.932   0.946   1.031
121   T         0.885   0.896   0.957   0.986   0.998   1.083   0.932   0.946   1.031
122   K         0.885   0.896   0.957   0.884   0.898   0.995   0.932   0.946   1.031
123   D         0.885   0.896   0.957   0.971   0.987   1.070   0.932   0.946   1.031
124   L         0.885   0.896   0.957   0.707   0.719   0.841   0.932   0.946   1.031
125   Q         0.885   0.896   0.957   0.907   0.929   1.014   0.932   0.946   1.031
126   M         0.885   0.896   0.957   1.135   1.144   1.213   0.932   0.946   1.031
127   V         0.885   0.896   0.957   0.783   0.808   0.907   0.932   0.946   1.031
128   N         0.885   0.896   0.957   0.933   0.947   1.038   0.932   0.946   1.031
129   I         0.885   0.896   0.957   0.858   0.875   0.972   0.932   0.946   1.031
130   T         0.166   0.004  -0.147   0.366   0.151  -0.108   0.153  -0.093  -0.370
131   C         0.885   0.896   0.957   1.201   1.210   1.270   0.932   0.946   1.031
132   R         0.885   0.896   0.957   0.819   0.837   0.938   0.932   0.946   1.031
133   V         0.885   0.896   0.957   0.783   0.808   0.907   0.932   0.946   1.031
134   L         0.885   0.896   0.957   0.707   0.719   0.841   0.932   0.946   1.031
135   S        -0.520  -0.409  -0.864  -0.290  -0.154  -0.739  -0.515  -0.372  -0.960
136   R        -0.189  -0.113  -0.198  -0.314  -0.195  -0.351  -0.404  -0.282  -0.460
137   P         0.885   0.896   0.957   1.030   1.043   1.121   0.932   0.946   1.031
138   D        -1.431  -1.416  -1.413  -1.274  -1.232  -1.262  -1.406  -1.365  -1.298
139   V        -0.378  -0.331  -0.236  -0.695  -0.606  -0.460  -0.738  -0.661  -0.527
140   V        -3.086  -2.979  -2.648  -2.501  -2.325  -1.944  -2.185  -2.097  -1.723
141   Q        -0.975  -0.925  -0.917  -1.171  -1.137  -1.043  -1.183  -1.130  -1.032
142   L         0.885   0.896   0.957   0.707   0.719   0.841   0.932   0.946   1.031
143   P         0.885   0.896   0.957   1.030   1.043   1.121   0.932   0.946   1.031
144   T        -1.762  -1.836  -1.799  -1.378  -1.522  -1.468  -1.517  -1.591  -1.459
145   I         0.885   0.896   0.957   0.858   0.875   0.972   0.932   0.946   1.031
146   Y         0.885   0.896   0.957   1.099   1.109   1.181   0.932   0.946   1.031
147   R         0.166   0.169  -0.157   0.196   0.205  -0.267   0.153   0.156  -0.386
148   T         0.885   0.896   0.957   0.986   0.998   1.083   0.932   0.946   1.031
149   L         0.885   0.896   0.957   0.707   0.719   0.841   0.932   0.946   1.031
150   G         0.885   0.896   0.957   0.864   0.878   0.978   0.932   0.946   1.031
151   Q        -2.424  -2.384  -2.136  -2.329  -2.270  -1.956  -1.962  -1.911  -1.584
152   D         0.166   0.220  -0.151   0.344   0.414  -0.145   0.153   0.229  -0.375
153   Y         0.885   0.896   0.957   1.099   1.109   1.181   0.932   0.946   1.031
154   D         0.166   0.220  -0.151   0.355   0.423  -0.115   0.153   0.229  -0.375
155   E         0.885   0.896   0.957   0.960   0.970   1.061   0.932   0.946   1.031
156   R        -0.189  -0.113  -0.198  -0.314  -0.195  -0.351  -0.404  -0.282  -0.460
157   V         0.885   0.896   0.957   0.783   0.808   0.907   0.932   0.946   1.031
158   L         0.885   0.896   0.957   0.707   0.719   0.841   0.932   0.946   1.031
159   P         0.885   0.896   0.957   1.030   1.043   1.121   0.932   0.946   1.031
160   S         0.885   0.896   0.957   0.896   0.914   1.005   0.932   0.946   1.031
161   I         0.166   0.169  -0.157   0.206   0.212  -0.319   0.153   0.156  -0.386
162   V         0.885   0.896   0.957   0.783   0.808   0.907   0.932   0.946   1.031
163   N         0.885   0.896   0.957   0.933   0.947   1.038   0.932   0.946   1.031
164   E         0.885   0.896   0.957   0.960   0.970   1.061   0.932   0.946   1.031
165   V         0.885   0.896   0.957   0.783   0.808   0.907   0.932   0.946   1.031
166   L         0.885   0.896   0.957   0.707   0.719   0.841   0.932   0.946   1.031
167   K         0.885   0.896   0.957   0.884   0.898   0.995   0.932   0.946   1.031
168   A        -0.378  -0.267  -0.222  -0.664  -0.443  -0.422  -0.738  -0.545  -0.502
169   V         0.885   0.896   0.957   0.783   0.808   0.907   0.932   0.946   1.031
170   V         0.885   0.896   0.957   0.783   0.808   0.907   0.932   0.946   1.031
171   A         0.885   0.896   0.957   0.726   0.741   0.857   0.932   0.946   1.031
172   Q         0.885   0.896   0.957   0.907   0.929   1.014   0.932   0.946   1.031
173   F         0.885   0.896   0.957   1.023   1.038   1.116   0.932   0.946   1.031
174   N         0.885   0.896   0.957   0.933   0.947   1.038   0.932   0.946   1.031
175   A         0.885   0.896   0.957   0.726   0.741   0.857   0.932   0.946   1.031
176   S         0.885   0.896   0.957   0.896   0.914   1.005   0.932   0.946   1.031
177   Q         0.885   0.896   0.957   0.907   0.929   1.014   0.932   0.946   1.031
178   L         0.885   0.896   0.957   0.707   0.719   0.841   0.932   0.946   1.031
179   I         0.885   0.896   0.957   0.858   0.875   0.972   0.932   0.946   1.031
180   T         0.885   0.896   0.957   0.986   0.998   1.083   0.932   0.946   1.031
181   Q         0.885   0.896   0.957   0.907   0.929   1.014   0.932   0.946   1.031
182   R         0.885   0.896   0.957   0.819   0.837   0.938   0.932   0.946   1.031
183   E         0.885   0.896   0.957   0.960   0.970   1.061   0.932   0.946   1.031
184   K        -0.975  -0.964  -0.910  -1.103  -1.043  -0.910  -1.183  -1.134  -1.023
185   V         0.885   0.896   0.957   0.783   0.808   0.907   0.932   0.946   1.031
186   S         0.166   0.083  -0.165   0.247   0.137  -0.298   0.153   0.028  -0.401
187   R         0.166   0.083  -0.165   0.193   0.089  -0.291   0.153   0.028  -0.401
188   L         0.885   0.896   0.957   0.707   0.719   0.841   0.932   0.946   1.031
189   I        -0.378  -0.267  -0.222  -0.695  -0.488  -0.435  -0.738  -0.545  -0.502
190   R        -0.189  -0.144  -0.216  -0.314  -0.244  -0.384  -0.404  -0.333  -0.492
191   E         0.166   0.294  -0.148   0.346   0.493  -0.114   0.153   0.331  -0.370
192   N         0.166   0.169  -0.157   0.310   0.315  -0.177   0.153   0.156  -0.386
193   L         0.885   0.896   0.957   0.707   0.719   0.841   0.932   0.946   1.031
194   V        -1.431  -1.564  -1.418  -1.476  -1.636  -1.414  -1.406  -1.527  -1.303
195   R        -0.378  -0.406  -0.244  -0.648  -0.708  -0.432  -0.738  -0.797  -0.542
196   R         0.885   0.896   0.957   0.819   0.837   0.938   0.932   0.946   1.031
197   A         0.885   0.896   0.957   0.726   0.741   0.857   0.932   0.946   1.031
198   S        -1.431  -1.399  -1.412  -1.460  -1.487  -1.454  -1.406  -1.394  -1.298
199   K        -1.431  -1.361  -1.411  -1.360  -1.333  -1.297  -1.406  -1.362  -1.297
200   F         0.885   0.896   0.957   1.023   1.038   1.116   0.932   0.946   1.031
201   N         0.885   0.896   0.957   0.933   0.947   1.038   0.932   0.946   1.031
202   I         0.166   0.220  -0.151   0.217   0.289  -0.276   0.153   0.229  -0.375
203   L        -0.520  -0.398  -0.860  -0.485  -0.342  -0.887  -0.515  -0.358  -0.955
204   L         0.885   0.896   0.957   0.707   0.719   0.841   0.932   0.946   1.031
205   D         0.885   0.896   0.957   0.971   0.987   1.070   0.932   0.946   1.031
206   D         0.885   0.896   0.957   0.971   0.987   1.070   0.932   0.946   1.031
207   V         0.885   0.896   0.957   0.783   0.808   0.907   0.932   0.946   1.031
208   S         0.885   0.896   0.957   0.896   0.914   1.005   0.932   0.946   1.031
209   I        -0.438  -0.388  -0.241  -0.862  -0.788  -0.520  -0.849  -0.764  -0.537
210   T         0.885   0.896   0.957   0.986   0.998   1.083   0.932   0.946   1.031
211   Y        -0.834  -0.872  -0.907  -0.505  -0.594  -0.628  -0.960  -1.047  -1.018
212   M        -0.520  -0.745  -0.877  -0.156  -0.502  -0.833  -0.515  -0.814  -0.977
213   T        -0.520  -0.745  -0.877  -0.281  -0.608  -0.886  -0.515  -0.814  -0.977
214   F         0.885   0.896   0.957   1.023   1.038   1.116   0.932   0.946   1.031
215   S         0.885   0.896   0.957   0.896   0.914   1.005   0.932   0.946   1.031
216   P         0.885   0.896   0.957   1.030   1.043   1.121   0.932   0.946   1.031
217   E         0.885   0.896   0.957   0.960   0.970   1.061   0.932   0.946   1.031
218   F         0.885   0.896   0.957   1.023   1.038   1.116   0.932   0.946   1.031
219   T        -0.189  -0.113  -0.198  -0.149  -0.032  -0.219  -0.404  -0.282  -0.460
220   N        -1.100  -0.941  -0.927  -1.351  -1.103  -1.061  -1.294  -1.077  -1.042
221   A         0.166   0.232  -0.153   0.101   0.184  -0.340   0.153   0.245  -0.379
222   V         0.885   0.896   0.957   0.783   0.808   0.907   0.932   0.946   1.031
223   E         0.885   0.896   0.957   0.960   0.970   1.061   0.932   0.946   1.031
224   A         0.885   0.896   0.957   0.726   0.741   0.857   0.932   0.946   1.031
225   K         0.885   0.896   0.957   0.884   0.898   0.995   0.932   0.946   1.031
226   Q         0.885   0.896   0.957   0.907   0.929   1.014   0.932   0.946   1.031
227   I         0.166   0.083  -0.165   0.217   0.110  -0.304   0.153   0.028  -0.401
228   A         0.885   0.896   0.957   0.726   0.741   0.857   0.932   0.946   1.031
229   Q         0.885   0.896   0.957   0.907   0.929   1.014   0.932   0.946   1.031
230   Q         0.885   0.896   0.957   0.907   0.929   1.014   0.932   0.946   1.031
231   D        -0.189  -0.230  -0.230  -0.143  -0.217  -0.259  -0.404  -0.481  -0.516
232   A         0.885   0.896   0.957   0.726   0.741   0.857   0.932   0.946   1.031
233   Q         0.885   0.896   0.957   0.907   0.929   1.014   0.932   0.946   1.031
234   R         0.166   0.232  -0.153   0.193   0.277  -0.270   0.153   0.245  -0.379
235   A         0.885   0.896   0.957   0.726   0.741   0.857   0.932   0.946   1.031
236   A         0.166   0.004  -0.147   0.114  -0.091  -0.293   0.153  -0.093  -0.370
237   F         0.885   0.896   0.957   1.023   1.038   1.116   0.932   0.946   1.031
238   V        -0.975  -1.062  -0.915  -1.157  -1.233  -0.967  -1.183  -1.262  -1.030
239   V         0.885   0.896   0.957   0.783   0.808   0.907   0.932   0.946   1.031
240   D         0.885   0.896   0.957   0.971   0.987   1.070   0.932   0.946   1.031
241   K        -0.189  -0.272  -0.220  -0.272  -0.429  -0.377  -0.404  -0.554  -0.499
242   A         0.885   0.896   0.957   0.726   0.741   0.857   0.932   0.946   1.031
243   R        -0.834  -0.718  -0.894  -0.889  -0.718  -0.954  -0.960  -0.804  -1.000
244   Q         0.166   0.004  -0.147   0.317   0.127  -0.090   0.153  -0.093  -0.370
245   E         0.885   0.896   0.957   0.960   0.970   1.061   0.932   0.946   1.031
246   K         0.885   0.896   0.957   0.884   0.898   0.995   0.932   0.946   1.031
247   Q         0.885   0.896   0.957   0.907   0.929   1.014   0.932   0.946   1.031
248   G        -0.834  -0.843  -0.903  -0.877  -0.883  -1.020  -0.960  -0.954  -1.012
249   M        -1.431  -1.492  -1.412  -1.246  -1.328  -1.295  -1.406  -1.453  -1.297
250   V        -0.378  -0.388  -0.241  -0.695  -0.714  -0.469  -0.738  -0.764  -0.537
251   V         0.885   0.896   0.957   0.783   0.808   0.907   0.932   0.946   1.031
252   R        -0.189  -0.219  -0.214  -0.272  -0.331  -0.365  -0.404  -0.461  -0.488
253   A         0.885   0.896   0.957   0.726   0.741   0.857   0.932   0.946   1.031
254   Q         0.166   0.239  -0.148   0.282   0.381  -0.186   0.153   0.256  -0.370
255   G         0.885   0.896   0.957   0.864   0.878   0.978   0.932   0.946   1.031
256   E         0.885   0.896   0.957   0.960   0.970   1.061   0.932   0.946   1.031
257   A         0.166   0.004  -0.147   0.096  -0.119  -0.344   0.153  -0.093  -0.370
258   K        -0.378  -0.406  -0.244  -0.625  -0.702  -0.430  -0.738  -0.797  -0.542
259   S         0.166   0.004  -0.147   0.247   0.023  -0.262   0.153  -0.093  -0.370
260   A         0.885   0.896   0.957   0.726   0.741   0.857   0.932   0.946   1.031
261   E        -0.189  -0.242  -0.216  -0.171  -0.269  -0.268  -0.404  -0.502  -0.491
262   L         0.885   0.896   0.957   0.707   0.719   0.841   0.932   0.946   1.031
263   I         0.166   0.239  -0.148   0.217   0.313  -0.271   0.153   0.256  -0.370
264   G         0.885   0.896   0.957   0.864   0.878   0.978   0.932   0.946   1.031
265   E        -0.189  -0.113  -0.215  -0.150  -0.039  -0.235  -0.404  -0.283  -0.490
266   A         0.885   0.896   0.957   0.726   0.741   0.857   0.932   0.946   1.031
267   I         0.885   0.896   0.957   0.858   0.875   0.972   0.932   0.946   1.031
268   K         0.885   0.896   0.957   0.884   0.898   0.995   0.932   0.946   1.031
269   K         0.166   0.004  -0.147   0.265   0.052  -0.189   0.153  -0.093  -0.370
270   S         0.166   0.004  -0.147   0.269   0.057  -0.199   0.153  -0.093  -0.370
271   R        -0.975  -1.015  -0.903  -1.112  -1.112  -0.934  -1.183  -1.191  -1.014
272   D        -0.520  -0.745  -0.877  -0.276  -0.594  -0.848  -0.515  -0.814  -0.977
273   Y         0.166   0.004  -0.147   0.491   0.280   0.015   0.153  -0.093  -0.370
274   V         0.166   0.004  -0.147   0.152  -0.053  -0.300   0.153  -0.093  -0.370
275   E         0.885   0.896   0.957   0.960   0.970   1.061   0.932   0.946   1.031
276   L         0.885   0.896   0.957   0.707   0.719   0.841   0.932   0.946   1.031
277   K         0.166   0.004  -0.147   0.249   0.028  -0.234   0.153  -0.093  -0.370
278   R        -0.189  -0.307  -0.227  -0.314  -0.524  -0.402  -0.404  -0.617  -0.510
279   L         0.885   0.896   0.957   0.707   0.719   0.841   0.932   0.946   1.031
280   D        -0.189  -0.307  -0.227  -0.143  -0.353  -0.253  -0.404  -0.617  -0.510
281   T         0.166   0.083  -0.165   0.366   0.258  -0.140   0.153   0.028  -0.401
282   A         0.885   0.896   0.957   0.726   0.741   0.857   0.932   0.946   1.031
283   R         0.166   0.294  -0.148   0.193   0.349  -0.260   0.153   0.331  -0.370
284   D        -0.834  -0.776  -0.894  -0.762  -0.667  -0.906  -0.960  -0.858  -1.000
285   I         0.885   0.896   0.957   0.858   0.875   0.972   0.932   0.946   1.031
286   A         0.885   0.896   0.957   0.726   0.741   0.857   0.932   0.946   1.031
287   K        -1.968  -1.803  -1.801  -1.781  -1.524  -1.519  -1.740  -1.561  -1.462
288   I         0.166   0.169  -0.157   0.217   0.225  -0.288   0.153   0.156  -0.386
289   L         0.166   0.083  -0.165   0.076  -0.033  -0.392   0.153   0.028  -0.401
290   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
291   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
292   A        -0.189  -0.245  -0.218  -0.401  -0.498  -0.449  -0.404  -0.507  -0.494
293   S        -2.424  -2.310  -2.135  -2.360  -2.202  -1.968  -1.962  -1.857  -1.583
294   S         0.166   0.083  -0.165   0.266   0.162  -0.240   0.153   0.028  -0.401
295   P        -1.165  -1.362  -1.404  -0.818  -1.120  -1.249  -1.072  -1.299  -1.288
296   N         0.885   0.896   0.957   0.933   0.947   1.038   0.932   0.946   1.031
297   R        -0.378  -0.388  -0.241  -0.648  -0.675  -0.428  -0.738  -0.764  -0.537
298   V        -0.975  -1.001  -0.919  -1.241  -1.263  -1.134  -1.183  -1.192  -1.035
299   I        -1.637  -1.568  -1.431  -1.723  -1.619  -1.415  -1.628  -1.565  -1.316
300   L         0.885   0.896   0.957   0.707   0.719   0.841   0.932   0.946   1.031
301   D         0.166   0.004  -0.147   0.351   0.141  -0.120   0.153  -0.093  -0.370
302   N        -0.520  -0.745  -0.877  -0.336  -0.669  -0.930  -0.515  -0.814  -0.977
303   E        -0.975  -1.052  -0.916  -0.985  -1.081  -0.878  -1.183  -1.247  -1.031
304   A        -1.512  -1.520  -1.422  -1.593  -1.564  -1.411  -1.517  -1.500  -1.307
305   L         0.885   0.896   0.957   0.707   0.719   0.841   0.932   0.946   1.031
306   L         0.166   0.083  -0.165   0.077  -0.033  -0.389   0.153   0.028  -0.401
307   L         0.885   0.896   0.957   0.707   0.719   0.841   0.932   0.946   1.031
308   N         0.166   0.004  -0.147   0.319   0.109  -0.135   0.153  -0.093  -0.370
309   T        -0.834  -0.992  -0.916  -0.761  -1.010  -0.929  -0.960  -1.158  -1.029
310   V        -1.762  -1.840  -1.803  -1.706  -1.826  -1.814  -1.517  -1.597  -1.463
311   V        -1.554  -1.629  -1.427  -1.583  -1.671  -1.349  -1.540  -1.598  -1.312
312   D         0.885   0.896   0.957   0.973   0.991   1.072   0.932   0.946   1.031
313   A        -2.453  -2.436  -2.147  -2.424  -2.396  -1.947  -1.976  -1.944  -1.590
314   R         0.885   0.896   0.957   0.821   0.840   0.940   0.932   0.946   1.031
315   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
316   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
317   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
318   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
319   R        -0.772  -0.675  -0.887  -0.710  -0.576  -0.927  -0.849  -0.724  -0.990
320   G        -0.070   0.048  -0.184  -0.060   0.107  -0.279  -0.208  -0.025  -0.434
321   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
322   K        -0.189  -0.199  -0.227  -0.235  -0.259  -0.330  -0.404  -0.428  -0.512
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P50085
Output conservation file - output/P50085
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
