1     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
2     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
19    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
20    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
21    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
22    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
23    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
24    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
25    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
26    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
27    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
28    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
29    M         1.233   1.246   1.343   1.423   1.437   1.571   1.316   1.335   1.483
30    S         0.539   0.493   0.301   0.519   0.453   0.145   0.541   0.471   0.119
31    A        -1.622  -1.664  -1.451  -1.624  -1.696  -1.376  -1.430  -1.455  -1.185
32    S         0.312   0.418   0.253   0.256   0.390   0.178   0.183   0.353   0.032
33    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
34    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
35    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
36    K        -1.221  -1.263  -1.067  -1.331  -1.421  -1.123  -1.234  -1.276  -1.020
37    I        -0.617  -0.562  -0.522  -0.921  -0.846  -0.746  -0.852  -0.791  -0.688
38    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
39    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
40    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
41    L         0.539   0.417   0.294   0.494   0.339   0.154   0.541   0.352   0.106
42    S        -1.001  -1.000  -0.997  -0.982  -0.962  -0.967  -1.008  -0.996  -0.950
43    Q        -1.640  -1.640  -1.437  -1.484  -1.481  -1.171  -1.450  -1.441  -1.174
44    K        -1.079  -1.163  -1.030  -1.215  -1.337  -1.133  -1.118  -1.186  -0.985
45    I        -1.200  -1.238  -1.044  -1.395  -1.428  -1.135  -1.229  -1.254  -1.000
46    K        -0.122  -0.183  -0.414   0.039  -0.039  -0.352  -0.123  -0.214  -0.531
47    V        -0.561  -0.590  -0.515  -0.771  -0.812  -0.694  -0.786  -0.814  -0.679
48    A         0.539   0.417   0.294   0.420   0.260   0.079   0.541   0.352   0.106
49    L         0.539   0.493   0.301   0.530   0.482   0.253   0.541   0.471   0.119
50    V         0.015   0.018   0.143  -0.268  -0.267  -0.081  -0.344  -0.346  -0.174
51    Q         1.233   1.246   1.343   1.395   1.415   1.545   1.316   1.335   1.483
52    L         0.539   0.554   0.310   0.504   0.528   0.205   0.541   0.563   0.134
53    S        -1.001  -0.904  -0.978  -1.167  -1.019  -1.119  -1.008  -0.886  -0.926
54    G        -1.079  -1.163  -1.030  -1.271  -1.364  -1.141  -1.118  -1.186  -0.985
55    S        -0.561  -0.622  -0.518  -0.751  -0.815  -0.644  -0.786  -0.840  -0.681
56    S        -1.001  -1.039  -1.011  -1.158  -1.204  -1.140  -1.008  -1.036  -0.963
57    P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
58    D         1.233   1.246   1.343   1.214   1.230   1.378   1.316   1.335   1.483
59    K         1.233   1.246   1.343   1.192   1.216   1.357   1.316   1.335   1.483
60    M        -1.079  -1.030  -1.010  -1.276  -1.210  -1.103  -1.118  -1.063  -0.965
61    A         0.539   0.417   0.294   0.430   0.274   0.104   0.541   0.352   0.106
62    N         1.233   1.246   1.343   1.322   1.341   1.478   1.316   1.335   1.483
63    L         0.539   0.554   0.310   0.484   0.508   0.156   0.541   0.563   0.134
64    Q        -1.519  -1.478  -1.406  -1.437  -1.383  -1.281  -1.340  -1.304  -1.149
65    R        -1.200  -1.240  -1.051  -1.165  -1.218  -0.945  -1.229  -1.256  -1.006
66    A         0.015   0.065   0.166  -0.376  -0.294  -0.134  -0.344  -0.256  -0.130
67    A        -1.079  -1.130  -1.024  -1.183  -1.240  -1.060  -1.118  -1.157  -0.979
68    T        -1.959  -1.972  -1.762  -1.851  -1.891  -1.582  -1.561  -1.561  -1.292
69    F        -0.561  -0.559  -0.514  -0.662  -0.673  -0.602  -0.786  -0.789  -0.679
70    I        -0.043  -0.020   0.139  -0.378  -0.336  -0.086  -0.455  -0.418  -0.183
71    E        -1.519  -1.567  -1.424  -1.543  -1.624  -1.408  -1.340  -1.374  -1.163
72    R        -1.838  -1.682  -1.724  -1.570  -1.341  -1.435  -1.450  -1.304  -1.264
73    A         1.233   1.246   1.343   1.026   1.043   1.204   1.316   1.335   1.483
74    M        -0.760  -0.704  -0.547  -0.952  -0.898  -0.648  -1.008  -0.936  -0.716
75    K        -1.320  -1.250  -1.370  -1.090  -0.996  -1.173  -1.118  -1.044  -1.112
76    E        -2.278  -2.187  -2.028  -2.007  -1.857  -1.691  -1.672  -1.598  -1.372
77    Q        -0.710  -0.721  -0.562  -0.796  -0.811  -0.579  -0.950  -0.958  -0.735
78    P        -0.517  -0.448  -0.526  -0.478  -0.379  -0.523  -0.667  -0.571  -0.686
79    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
80    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
81    D        -1.001  -0.904  -0.985  -1.000  -0.850  -0.972  -1.008  -0.888  -0.934
82    T        -1.519  -1.513  -1.423  -1.560  -1.583  -1.464  -1.340  -1.335  -1.162
83    K        -0.561  -0.523  -0.508  -0.594  -0.549  -0.461  -0.786  -0.752  -0.672
84    L        -0.425  -0.543  -0.507  -0.576  -0.749  -0.711  -0.565  -0.716  -0.666
85    V         0.539   0.417   0.294   0.579   0.417   0.214   0.541   0.352   0.106
86    V         0.539   0.622   0.319   0.619   0.713   0.350   0.541   0.662   0.150
87    L         1.233   1.246   1.343   1.092   1.113   1.265   1.316   1.335   1.483
88    P         1.233   1.246   1.343   1.245   1.260   1.407   1.316   1.335   1.483
89    E         1.233   1.246   1.343   1.236   1.255   1.398   1.316   1.335   1.483
90    C        -0.122  -0.176  -0.416   0.262   0.174  -0.215  -0.123  -0.205  -0.534
91    F         1.233   1.246   1.343   1.285   1.304   1.443   1.316   1.335   1.483
92    N         1.233   1.246   1.343   1.322   1.341   1.478   1.316   1.335   1.483
93    S         0.539   0.614   0.315   0.519   0.609   0.172   0.541   0.650   0.144
94    P         1.233   1.246   1.343   1.245   1.260   1.407   1.316   1.335   1.483
95    Y         1.233   1.246   1.343   1.324   1.340   1.480   1.316   1.335   1.483
96    S        -1.001  -1.012  -1.016  -1.172  -1.213  -1.175  -1.008  -1.038  -0.971
97    T        -0.425  -0.503  -0.503  -0.387  -0.499  -0.470  -0.565  -0.674  -0.661
98    D        -0.744  -0.835  -0.967  -0.564  -0.704  -0.928  -0.676  -0.787  -0.912
99    Q        -1.320  -1.392  -1.396  -0.943  -1.053  -1.141  -1.118  -1.194  -1.136
100   F         1.233   1.246   1.343   1.285   1.304   1.443   1.316   1.335   1.483
101   R        -1.001  -1.091  -1.019  -0.867  -1.008  -0.937  -1.008  -1.105  -0.973
102   K        -1.519  -1.543  -1.416  -1.362  -1.381  -1.206  -1.340  -1.350  -1.155
103   Y         1.233   1.246   1.343   1.324   1.340   1.480   1.316   1.335   1.483
104   S         0.197   0.236   0.201  -0.076  -0.020  -0.096  -0.012   0.051  -0.065
105   E         1.233   1.246   1.343   1.236   1.255   1.398   1.316   1.335   1.483
106   V        -1.838  -1.853  -1.748  -1.629  -1.650  -1.521  -1.450  -1.461  -1.282
107   I         0.539   0.493   0.301   0.531   0.477   0.170   0.541   0.471   0.119
108   N        -1.221  -1.145  -1.040  -1.231  -1.126  -0.980  -1.234  -1.148  -0.992
109   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
110   P         0.539   0.417   0.294   0.650   0.490   0.296   0.541   0.352   0.106
111   K        -1.519  -1.418  -1.401  -1.447  -1.318  -1.253  -1.340  -1.238  -1.144
112   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
113   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
114   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
115   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
116   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
117   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
118   S        -0.760  -0.720  -0.559  -1.126  -1.064  -0.824  -1.008  -0.955  -0.731
119   T        -0.760  -0.708  -0.553  -0.898  -0.820  -0.589  -1.008  -0.941  -0.724
120   S         0.015   0.065   0.166  -0.226  -0.146   0.005  -0.344  -0.256  -0.130
121   V        -1.079  -1.163  -1.030  -1.045  -1.138  -0.929  -1.118  -1.186  -0.985
122   Q        -1.519  -1.486  -1.404  -1.210  -1.152  -1.072  -1.340  -1.301  -1.146
123   F        -1.001  -0.904  -0.978  -1.191  -1.037  -1.126  -1.008  -0.886  -0.926
124   L         1.233   1.246   1.343   1.092   1.113   1.265   1.316   1.335   1.483
125   S         0.539   0.556   0.308   0.543   0.560   0.216   0.541   0.565   0.132
126   N        -1.519  -1.496  -1.420  -1.508  -1.490  -1.363  -1.340  -1.309  -1.160
127   L        -0.682  -0.702  -0.559  -0.858  -0.869  -0.654  -0.897  -0.929  -0.731
128   A         1.233   1.246   1.343   1.026   1.043   1.204   1.316   1.335   1.483
129   N        -1.001  -0.905  -0.989  -0.866  -0.746  -0.812  -1.008  -0.905  -0.941
130   K        -0.425  -0.490  -0.507  -0.439  -0.558  -0.570  -0.565  -0.673  -0.666
131   F        -1.838  -1.827  -1.737  -1.287  -1.293  -1.175  -1.450  -1.440  -1.274
132   K        -1.001  -0.986  -0.995  -1.018  -0.993  -1.026  -1.008  -0.988  -0.949
133   I        -0.744  -0.788  -0.954  -0.638  -0.698  -0.973  -0.676  -0.734  -0.898
134   I        -1.200  -1.129  -1.033  -1.139  -1.029  -0.909  -1.229  -1.150  -0.987
135   L         0.197   0.284   0.240  -0.010   0.129   0.033  -0.012   0.132   0.007
136   V        -0.425  -0.487  -0.487  -0.466  -0.536  -0.567  -0.565  -0.631  -0.638
137   G         1.233   1.246   1.343   1.169   1.190   1.336   1.316   1.335   1.483
138   G         1.233   1.246   1.343   1.169   1.190   1.336   1.316   1.335   1.483
139   T         0.539   0.594   0.313   0.554   0.616   0.251   0.541   0.620   0.140
140   I         0.539   0.554   0.310   0.564   0.590   0.267   0.541   0.563   0.134
141   P         1.233   1.246   1.343   1.245   1.260   1.407   1.316   1.335   1.483
142   E         1.233   1.246   1.343   1.236   1.255   1.398   1.316   1.335   1.483
143   L        -0.527  -0.532  -0.508  -0.667  -0.682  -0.632  -0.707  -0.724  -0.668
144   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
145   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
146   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
147   D        -0.630  -0.587  -0.530  -0.748  -0.697  -0.605  -0.848  -0.804  -0.695
148   P        -0.630  -0.600  -0.539  -0.715  -0.688  -0.568  -0.848  -0.816  -0.707
149   K        -1.959  -1.927  -1.758  -1.901  -1.851  -1.634  -1.561  -1.527  -1.290
150   T        -1.519  -1.580  -1.428  -1.365  -1.456  -1.279  -1.340  -1.382  -1.166
151   D         0.197   0.137   0.173   0.116   0.004   0.020  -0.012  -0.126  -0.117
152   K         0.539   0.556   0.308   0.609   0.637   0.303   0.541   0.565   0.132
153   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
154   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
155   I        -0.744  -0.883  -0.977  -0.626  -0.829  -0.987  -0.676  -0.843  -0.923
156   Y         0.539   0.606   0.318   0.735   0.815   0.422   0.541   0.638   0.150
157   N         1.233   1.246   1.343   1.322   1.341   1.478   1.316   1.335   1.483
158   T         1.233   1.246   1.343   1.269   1.291   1.429   1.316   1.335   1.483
159   S        -0.122  -0.228  -0.428  -0.034  -0.197  -0.468  -0.123  -0.271  -0.551
160   I        -0.744  -0.804  -0.962  -0.649  -0.721  -0.948  -0.676  -0.752  -0.907
161   I        -1.200  -1.183  -1.045  -1.355  -1.337  -1.140  -1.229  -1.209  -1.000
162   F         0.539   0.556   0.308   0.677   0.701   0.324   0.541   0.565   0.132
163   N        -1.001  -1.098  -1.008  -0.902  -1.044  -0.954  -1.008  -1.101  -0.961
164   E         0.015   0.060   0.157  -0.155  -0.081   0.048  -0.344  -0.267  -0.148
165   D        -1.200  -1.155  -1.044  -1.246  -1.213  -0.996  -1.229  -1.188  -0.999
166   G         1.233   1.246   1.343   1.169   1.190   1.336   1.316   1.335   1.483
167   K        -1.001  -0.931  -0.980  -0.985  -0.866  -0.963  -1.008  -0.913  -0.931
168   L         0.015  -0.006   0.137  -0.319  -0.369  -0.154  -0.344  -0.390  -0.185
169   I         0.539   0.493   0.301   0.531   0.477   0.170   0.541   0.471   0.119
170   D        -0.744  -0.642  -0.942  -0.764  -0.631  -1.062  -0.676  -0.553  -0.885
171   K        -0.744  -0.836  -0.969  -0.583  -0.723  -0.942  -0.676  -0.791  -0.915
172   H         1.233   1.246   1.343   1.404   1.423   1.553   1.316   1.335   1.483
173   R         1.233   1.246   1.343   1.320   1.334   1.476   1.316   1.335   1.483
174   K         1.233   1.246   1.343   1.192   1.216   1.357   1.316   1.335   1.483
175   V        -1.200  -1.223  -1.035  -1.473  -1.491  -1.225  -1.229  -1.237  -0.990
176   H         1.233   1.246   1.343   1.404   1.423   1.553   1.316   1.335   1.483
177   L         1.233   1.246   1.343   1.092   1.113   1.265   1.316   1.335   1.483
178   F         1.233   1.246   1.343   1.285   1.304   1.443   1.316   1.335   1.483
179   D         1.233   1.246   1.343   1.214   1.230   1.378   1.316   1.335   1.483
180   V         0.539   0.594   0.313   0.545   0.617   0.224   0.541   0.620   0.140
181   D         1.233   1.246   1.343   1.214   1.230   1.378   1.316   1.335   1.483
182   I         0.539   0.554   0.310   0.545   0.570   0.219   0.541   0.563   0.134
183   P         1.233   1.246   1.343   1.245   1.260   1.407   1.316   1.335   1.483
184   N        -0.043  -0.020   0.137  -0.263  -0.232   0.011  -0.455  -0.416  -0.186
185   G         0.015   0.016   0.141  -0.246  -0.247  -0.065  -0.344  -0.349  -0.177
186   I         0.539   0.417   0.294   0.545   0.391   0.193   0.541   0.352   0.106
187   S        -0.425  -0.503  -0.503  -0.406  -0.537  -0.572  -0.565  -0.674  -0.661
188   F         1.233   1.246   1.343   1.285   1.304   1.443   1.316   1.335   1.483
189   H        -0.744  -0.749  -0.949  -0.480  -0.494  -0.726  -0.676  -0.689  -0.893
190   E         1.233   1.246   1.343   1.236   1.255   1.398   1.316   1.335   1.483
191   S         0.539   0.606   0.318   0.529   0.608   0.199   0.541   0.638   0.150
192   E        -1.640  -1.577  -1.435  -1.687  -1.593  -1.398  -1.450  -1.391  -1.173
193   T        -0.122  -0.284  -0.439   0.064  -0.161  -0.441  -0.123  -0.344  -0.566
194   L         1.233   1.246   1.343   1.092   1.113   1.265   1.316   1.335   1.483
195   S         0.197   0.214   0.190   0.081   0.099   0.046  -0.012   0.012  -0.084
196   P        -0.561  -0.524  -0.508  -0.738  -0.696  -0.655  -0.786  -0.755  -0.671
197   G         1.233   1.246   1.343   1.169   1.190   1.336   1.316   1.335   1.483
198   E        -0.425  -0.377  -0.485  -0.384  -0.324  -0.474  -0.565  -0.507  -0.636
199   K        -0.122  -0.284  -0.439  -0.040  -0.271  -0.566  -0.123  -0.344  -0.566
200   S        -1.959  -1.937  -1.759  -1.914  -1.854  -1.581  -1.561  -1.536  -1.291
201   T         1.233   1.246   1.343   1.269   1.291   1.429   1.316   1.335   1.483
202   T        -1.200  -1.155  -1.034  -1.251  -1.177  -0.970  -1.229  -1.183  -0.988
203   I        -0.760  -0.708  -0.553  -0.959  -0.881  -0.657  -1.008  -0.941  -0.724
204   -        -0.006   0.066   0.166  -0.243  -0.109   0.021  -0.384  -0.254  -0.131
205   D        -0.561  -0.535  -0.507  -0.712  -0.669  -0.570  -0.786  -0.748  -0.668
206   T        -1.200  -1.151  -1.031  -1.228  -1.143  -0.974  -1.229  -1.170  -0.985
207   K        -1.079  -1.092  -1.022  -1.120  -1.127  -1.019  -1.118  -1.121  -0.978
208   Y        -0.122  -0.001  -0.387   0.135   0.287  -0.272  -0.123   0.039  -0.494
209   G         1.233   1.246   1.343   1.169   1.190   1.336   1.316   1.335   1.483
210   K        -0.425  -0.399  -0.462  -0.389  -0.332  -0.425  -0.565  -0.513  -0.600
211   F        -0.760  -0.713  -0.545  -0.968  -0.893  -0.646  -1.008  -0.949  -0.715
212   G         0.539   0.493   0.301   0.544   0.486   0.167   0.541   0.471   0.119
213   V        -0.043  -0.027   0.135  -0.418  -0.395  -0.132  -0.455  -0.431  -0.190
214   G         0.539   0.493   0.301   0.544   0.486   0.167   0.541   0.471   0.119
215   I         1.233   1.246   1.343   1.147   1.170   1.316   1.316   1.335   1.483
216   C         1.233   1.246   1.343   1.453   1.468   1.599   1.316   1.335   1.483
217   Y         1.233   1.246   1.343   1.324   1.340   1.480   1.316   1.335   1.483
218   D         1.233   1.246   1.343   1.214   1.230   1.378   1.316   1.335   1.483
219   M        -0.425  -0.357  -0.475  -0.434  -0.333  -0.511  -0.565  -0.463  -0.619
220   R         1.233   1.246   1.343   1.320   1.334   1.476   1.316   1.335   1.483
221   F         1.233   1.246   1.343   1.285   1.304   1.443   1.316   1.335   1.483
222   P         1.233   1.246   1.343   1.245   1.260   1.407   1.316   1.335   1.483
223   E         1.233   1.246   1.343   1.236   1.255   1.398   1.316   1.335   1.483
224   L        -0.122  -0.104  -0.409  -0.064  -0.039  -0.435  -0.123  -0.098  -0.524
225   A         1.233   1.246   1.343   1.026   1.043   1.204   1.316   1.335   1.483
226   M        -0.122  -0.042  -0.394   0.192   0.290  -0.284  -0.123  -0.017  -0.503
227   L        -0.744  -0.642  -0.942  -0.638  -0.494  -0.953  -0.676  -0.553  -0.885
228   S         0.197   0.271   0.218  -0.076   0.036  -0.065  -0.012   0.111  -0.033
229   A         0.197   0.284   0.240  -0.076   0.056  -0.026  -0.012   0.132   0.007
230   R         1.233   1.246   1.343   1.320   1.334   1.476   1.316   1.335   1.483
231   K        -0.425  -0.395  -0.490  -0.388  -0.362  -0.468  -0.565  -0.547  -0.644
232   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
233   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
234   G         0.197   0.284   0.240   0.122   0.252   0.174  -0.012   0.132   0.007
235   A        -0.682  -0.681  -0.543  -0.902  -0.881  -0.654  -0.897  -0.902  -0.710
236   F         0.539   0.417   0.294   0.676   0.515   0.299   0.541   0.352   0.106
237   A         0.539   0.417   0.294   0.423   0.263   0.085   0.541   0.352   0.106
238   M         0.539   0.493   0.301   0.807   0.744   0.415   0.541   0.471   0.119
239   I        -0.425  -0.399  -0.462  -0.470  -0.416  -0.524  -0.565  -0.513  -0.600
240   Y         1.233   1.246   1.343   1.324   1.340   1.480   1.316   1.335   1.483
241   P         1.233   1.246   1.343   1.245   1.260   1.407   1.316   1.335   1.483
242   S         0.197   0.271   0.218   0.064   0.182   0.058  -0.012   0.111  -0.033
243   A         1.233   1.246   1.343   1.026   1.043   1.204   1.316   1.335   1.483
244   F         1.233   1.246   1.343   1.285   1.304   1.443   1.316   1.335   1.483
245   N         1.233   1.246   1.343   1.322   1.341   1.478   1.316   1.335   1.483
246   T         0.539   0.417   0.294   0.654   0.493   0.267   0.541   0.352   0.106
247   V        -0.425  -0.500  -0.492  -0.399  -0.502  -0.542  -0.565  -0.650  -0.644
248   T         1.233   1.246   1.343   1.269   1.291   1.429   1.316   1.335   1.483
249   G         1.233   1.246   1.343   1.169   1.190   1.336   1.316   1.335   1.483
250   P         1.233   1.246   1.343   1.245   1.260   1.407   1.316   1.335   1.483
251   L         0.539   0.614   0.315   0.525   0.615   0.263   0.541   0.650   0.144
252   H         1.233   1.246   1.343   1.404   1.423   1.553   1.316   1.335   1.483
253   W         1.233   1.246   1.343   1.493   1.510   1.636   1.316   1.335   1.483
254   H        -0.744  -0.882  -0.981  -0.310  -0.507  -0.676  -0.676  -0.842  -0.928
255   L         1.233   1.246   1.343   1.092   1.113   1.265   1.316   1.335   1.483
256   L         0.539   0.493   0.301   0.521   0.472   0.232   0.541   0.471   0.119
257   A         0.539   0.493   0.301   0.420   0.362   0.090   0.541   0.471   0.119
258   R        -0.122  -0.114  -0.405   0.156   0.167  -0.252  -0.123  -0.114  -0.519
259   S         0.197   0.271   0.218  -0.076   0.036  -0.065  -0.012   0.111  -0.033
260   R         1.233   1.246   1.343   1.320   1.334   1.476   1.316   1.335   1.483
261   A         0.197   0.248   0.202  -0.076  -0.001  -0.093  -0.012   0.071  -0.062
262   V        -0.122  -0.106  -0.411   0.023   0.045  -0.374  -0.123  -0.105  -0.527
263   D         1.233   1.246   1.343   1.214   1.230   1.378   1.316   1.335   1.483
264   N         1.233   1.246   1.343   1.322   1.341   1.478   1.316   1.335   1.483
265   Q        -0.043  -0.027   0.135  -0.162  -0.135   0.108  -0.455  -0.431  -0.189
266   V        -1.519  -1.455  -1.408  -1.403  -1.315  -1.242  -1.340  -1.283  -1.150
267   Y         0.015   0.022   0.150  -0.061  -0.056   0.120  -0.344  -0.337  -0.162
268   V         0.015   0.063   0.156  -0.188  -0.108   0.020  -0.344  -0.260  -0.150
269   M        -1.519  -1.466  -1.414  -1.585  -1.553  -1.418  -1.340  -1.298  -1.156
270   L        -0.122  -0.230  -0.425  -0.086  -0.216  -0.506  -0.123  -0.273  -0.546
271   C         1.233   1.246   1.343   1.453   1.468   1.599   1.316   1.335   1.483
272   S         0.539   0.417   0.294   0.519   0.345   0.132   0.541   0.352   0.106
273   P         1.233   1.246   1.343   1.245   1.260   1.407   1.316   1.335   1.483
274   A         1.233   1.246   1.343   1.026   1.043   1.204   1.316   1.335   1.483
275   R         0.539   0.554   0.310   0.747   0.764   0.442   0.541   0.563   0.134
276   N        -0.744  -0.641  -0.950  -0.550  -0.417  -0.874  -0.676  -0.551  -0.893
277   L        -1.959  -1.972  -1.762  -1.888  -1.882  -1.584  -1.561  -1.561  -1.292
278   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
279   Q        -1.001  -1.040  -1.013  -0.924  -0.992  -0.917  -1.008  -1.060  -0.968
280   S        -0.682  -0.681  -0.543  -0.980  -1.014  -0.804  -0.897  -0.902  -0.710
281   S        -1.001  -1.081  -1.017  -1.025  -1.149  -1.050  -1.008  -1.091  -0.971
282   Y         1.233   1.246   1.343   1.324   1.340   1.480   1.316   1.335   1.483
283   H        -0.043  -0.018   0.139  -0.044  -0.002   0.222  -0.455  -0.414  -0.181
284   A         0.539   0.417   0.294   0.417   0.254   0.069   0.541   0.352   0.106
285   Y        -0.425  -0.469  -0.498  -0.209  -0.279  -0.309  -0.565  -0.640  -0.655
286   G         1.233   1.246   1.343   1.169   1.190   1.336   1.316   1.335   1.483
287   H         1.233   1.246   1.343   1.404   1.423   1.553   1.316   1.335   1.483
288   S         1.233   1.246   1.343   1.144   1.157   1.314   1.316   1.335   1.483
289   I        -0.122  -0.194  -0.423  -0.098  -0.192  -0.530  -0.123  -0.228  -0.544
290   V        -0.122  -0.160  -0.420   0.028  -0.024  -0.378  -0.123  -0.174  -0.540
291   V        -0.425  -0.350  -0.471  -0.516  -0.417  -0.631  -0.565  -0.474  -0.616
292   D         0.539   0.614   0.315   0.631   0.719   0.334   0.541   0.650   0.144
293   P         1.233   1.246   1.343   1.245   1.260   1.407   1.316   1.335   1.483
294   R        -1.959  -1.933  -1.754  -1.673  -1.640  -1.401  -1.561  -1.532  -1.287
295   G         0.539   0.493   0.301   0.544   0.486   0.167   0.541   0.471   0.119
296   K        -1.320  -1.212  -1.367  -1.118  -0.963  -1.211  -1.118  -1.005  -1.109
297   I         0.197   0.109   0.167   0.056  -0.096  -0.036  -0.012  -0.175  -0.128
298   V        -0.425  -0.403  -0.488  -0.545  -0.525  -0.666  -0.565  -0.548  -0.640
299   A        -0.122  -0.160  -0.420  -0.126  -0.177  -0.495  -0.123  -0.174  -0.540
300   E         0.539   0.417   0.294   0.646   0.493   0.300   0.541   0.352   0.106
301   A         0.539   0.417   0.294   0.435   0.282   0.116   0.541   0.352   0.106
302   G        -0.561  -0.598  -0.513  -0.714  -0.763  -0.609  -0.786  -0.826  -0.678
303   E        -0.122  -0.104  -0.409   0.032   0.057  -0.414  -0.123  -0.098  -0.524
304   G        -1.838  -1.888  -1.744  -1.655  -1.746  -1.540  -1.450  -1.490  -1.279
305   E         0.539   0.417   0.294   0.642   0.487   0.292   0.541   0.352   0.106
306   E        -0.425  -0.544  -0.503  -0.400  -0.578  -0.546  -0.565  -0.717  -0.661
307   I        -0.122  -0.104  -0.409  -0.037  -0.008  -0.446  -0.123  -0.098  -0.524
308   I        -0.561  -0.492  -0.496  -0.794  -0.680  -0.670  -0.786  -0.694  -0.654
309   Y        -0.425  -0.433  -0.482  -0.312  -0.318  -0.435  -0.565  -0.564  -0.631
310   A         0.539   0.556   0.308   0.417   0.438   0.094   0.541   0.565   0.132
311   E        -0.425  -0.428  -0.491  -0.397  -0.432  -0.511  -0.565  -0.593  -0.645
312   L         0.539   0.417   0.294   0.484   0.327   0.130   0.541   0.352   0.106
313   D         0.539   0.554   0.310   0.619   0.637   0.295   0.541   0.563   0.134
314   P        -0.122  -0.114  -0.405   0.045   0.050  -0.391  -0.123  -0.114  -0.519
315   E        -1.320  -1.346  -1.383  -1.091  -1.148  -1.228  -1.118  -1.149  -1.124
316   V        -1.079  -1.086  -1.013  -1.218  -1.208  -1.077  -1.118  -1.112  -0.968
317   I        -0.561  -0.619  -0.513  -0.768  -0.807  -0.621  -0.786  -0.835  -0.674
318   E        -1.519  -1.509  -1.413  -1.482  -1.475  -1.366  -1.340  -1.320  -1.152
319   S        -1.640  -1.594  -1.434  -1.671  -1.595  -1.386  -1.450  -1.405  -1.172
320   F        -0.744  -0.641  -0.950  -0.720  -0.586  -0.991  -0.676  -0.551  -0.893
321   R         1.233   1.246   1.343   1.320   1.334   1.476   1.316   1.335   1.483
322   Q        -1.838  -1.852  -1.744  -1.460  -1.496  -1.405  -1.450  -1.461  -1.279
323   A        -1.001  -1.040  -1.003  -1.077  -1.122  -1.078  -1.008  -1.037  -0.955
324   V         0.197   0.155   0.175   0.056  -0.016  -0.021  -0.012  -0.093  -0.113
325   P         1.233   1.246   1.343   1.245   1.260   1.407   1.316   1.335   1.483
326   L        -0.682  -0.715  -0.565  -0.923  -0.994  -0.786  -0.897  -0.944  -0.738
327   T        -1.519  -1.576  -1.430  -1.247  -1.317  -1.125  -1.340  -1.378  -1.167
328   K        -1.519  -1.443  -1.404  -1.322  -1.211  -1.169  -1.340  -1.257  -1.144
329   Q         1.233   1.246   1.343   1.395   1.415   1.545   1.316   1.335   1.483
330   R         1.233   1.246   1.343   1.320   1.334   1.476   1.316   1.335   1.483
331   R         0.539   0.606   0.318   0.718   0.798   0.388   0.541   0.638   0.150
332   F         1.233   1.246   1.343   1.285   1.304   1.443   1.316   1.335   1.483
333   D         1.233   1.246   1.343   1.214   1.230   1.378   1.316   1.335   1.483
334   V        -0.561  -0.534  -0.498  -0.785  -0.738  -0.687  -0.786  -0.746  -0.658
335   Y         1.233   1.246   1.343   1.324   1.340   1.480   1.316   1.335   1.483
336   S        -1.200  -1.150  -1.041  -1.292  -1.242  -1.065  -1.229  -1.182  -0.996
337   D         0.539   0.417   0.294   0.619   0.460   0.269   0.541   0.352   0.106
338   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
339   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
340   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
341   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
342   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
343   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
344   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
345   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
346   V         0.539   0.417   0.294   0.586   0.427   0.230   0.541   0.352   0.106
347   N        -0.122  -0.194  -0.423  -0.029  -0.139  -0.450  -0.123  -0.228  -0.544
348   A        -1.959  -1.972  -1.762  -1.921  -1.929  -1.617  -1.561  -1.561  -1.292
349   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
350   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
351   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
352   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
353   H        -1.838  -1.868  -1.738  -1.605  -1.652  -1.479  -1.450  -1.474  -1.275
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P49954
Output conservation file - output/P49954
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
