1     M         0.895   0.920   0.977   1.194   1.222   1.281   0.937   0.970   1.050
2     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     -        -0.486  -0.439  -0.280  -0.936  -0.875  -0.593  -0.878  -0.806  -0.562
4     S        -0.971  -0.975  -0.975  -1.173  -1.137  -1.141  -1.125  -1.095  -1.052
5     R         0.200   0.322  -0.175   0.304   0.440  -0.183   0.220   0.382  -0.379
6     P         0.895   0.920   0.977   0.992   1.024   1.104   0.937   0.970   1.050
7     Q        -0.373  -0.405  -0.274  -0.336  -0.422  -0.247  -0.677  -0.745  -0.552
8     V         0.895   0.920   0.977   0.708   0.758   0.854   0.937   0.970   1.050
9     T        -0.971  -0.882  -0.979  -1.048  -0.939  -1.092  -1.125  -1.035  -1.057
10    V        -0.373  -0.405  -0.274  -0.610  -0.653  -0.434  -0.677  -0.745  -0.552
11    H        -2.561  -2.371  -2.255  -2.012  -1.788  -1.689  -2.021  -1.860  -1.626
12    S        -0.795  -0.901  -0.974  -0.729  -0.945  -0.996  -0.856  -1.032  -1.051
13    L        -1.831  -1.789  -1.527  -2.214  -2.209  -1.796  -1.752  -1.687  -1.359
14    T        -2.445  -2.236  -2.257  -1.940  -1.651  -1.764  -1.932  -1.729  -1.627
15    G         0.895   0.920   0.977   0.839   0.871   0.969   0.937   0.970   1.050
16    E        -1.218  -1.225  -1.016  -1.298  -1.359  -1.065  -1.394  -1.388  -1.100
17    A        -2.138  -2.033  -1.921  -2.177  -2.044  -1.768  -1.842  -1.719  -1.514
18    T        -1.394  -1.349  -1.486  -1.240  -1.194  -1.484  -1.304  -1.241  -1.318
19    A        -0.795  -0.844  -0.976  -0.792  -0.937  -1.157  -0.856  -0.976  -1.054
20    N        -2.138  -2.023  -1.913  -1.931  -1.777  -1.653  -1.842  -1.710  -1.508
21    A        -1.947  -1.613  -1.902  -1.616  -1.171  -1.612  -1.663  -1.319  -1.498
22    L        -1.394  -1.493  -1.496  -1.217  -1.357  -1.364  -1.304  -1.414  -1.331
23    P        -1.087  -1.150  -0.996  -1.187  -1.377  -1.191  -1.214  -1.299  -1.077
24    L         0.895   0.920   0.977   0.849   0.883   0.978   0.937   0.970   1.050
25    P         0.895   0.920   0.977   0.992   1.024   1.104   0.937   0.970   1.050
26    A        -0.795  -0.956  -0.963  -0.923  -1.156  -1.128  -0.856  -1.037  -1.034
27    V         0.895   0.920   0.977   0.708   0.758   0.854   0.937   0.970   1.050
28    F         0.895   0.920   0.977   1.109   1.140   1.206   0.937   0.970   1.050
29    S        -2.138  -2.066  -1.928  -2.335  -2.214  -2.009  -1.842  -1.745  -1.519
30    A         0.895   0.920   0.977   0.606   0.642   0.764   0.937   0.970   1.050
31    P         0.895   0.920   0.977   0.992   1.024   1.104   0.937   0.970   1.050
32    I        -0.160  -0.023  -0.208  -0.068   0.137  -0.238  -0.318  -0.107  -0.436
33    R         0.895   0.920   0.977   0.854   0.888   0.983   0.937   0.970   1.050
34    P         0.895   0.920   0.977   0.992   1.024   1.104   0.937   0.970   1.050
35    D         0.895   0.920   0.977   1.120   1.150   1.216   0.937   0.970   1.050
36    I        -0.473  -0.440  -0.280  -0.641  -0.587  -0.336  -0.856  -0.808  -0.561
37    V         0.895   0.920   0.977   0.708   0.758   0.854   0.937   0.970   1.050
38    H        -0.795  -0.956  -0.963  -0.508  -0.758  -0.874  -0.856  -1.037  -1.034
39    T        -0.467  -0.590  -0.933  -0.230  -0.380  -0.821  -0.408  -0.589  -0.996
40    V         0.895   0.920   0.977   0.708   0.758   0.854   0.937   0.970   1.050
41    F        -0.971  -1.043  -0.992  -0.649  -0.746  -0.650  -1.125  -1.199  -1.072
42    T        -0.373  -0.231  -0.249  -0.532  -0.274  -0.389  -0.677  -0.443  -0.507
43    S        -1.831  -1.753  -1.526  -2.081  -1.977  -1.633  -1.752  -1.654  -1.358
44    V         0.200  -0.037  -0.194   0.180  -0.074  -0.254   0.220  -0.130  -0.410
45    N        -0.473  -0.432  -0.277  -0.789  -0.792  -0.521  -0.856  -0.794  -0.556
46    K         0.895   0.920   0.977   0.754   0.791   0.894   0.937   0.970   1.050
47    N         0.895   0.920   0.977   1.000   1.037   1.111   0.937   0.970   1.050
48    K         0.895   0.920   0.977   0.754   0.791   0.894   0.937   0.970   1.050
49    R         0.895   0.920   0.977   0.854   0.888   0.983   0.937   0.970   1.050
50    Q         0.895   0.920   0.977   1.047   1.080   1.152   0.937   0.970   1.050
51    A        -0.373  -0.405  -0.274  -0.722  -0.774  -0.526  -0.677  -0.745  -0.552
52    Y         0.895   0.920   0.977   1.160   1.194   1.251   0.937   0.970   1.050
53    A         0.200  -0.037  -0.194   0.033  -0.269  -0.487   0.220  -0.130  -0.410
54    V         0.895   0.920   0.977   0.708   0.758   0.854   0.937   0.970   1.050
55    S        -0.160  -0.148  -0.249  -0.266  -0.252  -0.515  -0.318  -0.306  -0.507
56    E        -0.467  -0.451  -0.923  -0.066  -0.064  -0.715  -0.408  -0.392  -0.983
57    K        -0.160  -0.148  -0.249  -0.257  -0.243  -0.388  -0.318  -0.306  -0.507
58    A         0.895   0.920   0.977   0.606   0.642   0.764   0.937   0.970   1.050
59    G         0.895   0.920   0.977   0.839   0.871   0.969   0.937   0.970   1.050
60    H         0.200   0.124  -0.185   0.571   0.484   0.014   0.220   0.112  -0.396
61    Q         0.895   0.920   0.977   1.047   1.080   1.152   0.937   0.970   1.050
62    T         0.895   0.920   0.977   0.954   0.993   1.070   0.937   0.970   1.050
63    S         0.895   0.920   0.977   0.858   0.903   0.985   0.937   0.970   1.050
64    A         0.895   0.920   0.977   0.606   0.642   0.764   0.937   0.970   1.050
65    E         0.895   0.920   0.977   1.038   1.069   1.144   0.937   0.970   1.050
66    S         0.895   0.920   0.977   0.858   0.903   0.985   0.937   0.970   1.050
67    W         0.895   0.920   0.977   1.175   1.207   1.265   0.937   0.970   1.050
68    G         0.895   0.920   0.977   0.839   0.871   0.969   0.937   0.970   1.050
69    T         0.895   0.920   0.977   0.954   0.993   1.070   0.937   0.970   1.050
70    G         0.895   0.920   0.977   0.839   0.871   0.969   0.937   0.970   1.050
71    R         0.895   0.920   0.977   0.854   0.888   0.983   0.937   0.970   1.050
72    A         0.895   0.920   0.977   0.606   0.642   0.764   0.937   0.970   1.050
73    V        -0.160  -0.100  -0.201  -0.347  -0.251  -0.420  -0.318  -0.229  -0.423
74    A         0.895   0.920   0.977   0.606   0.642   0.764   0.937   0.970   1.050
75    R         0.895   0.920   0.977   0.854   0.888   0.983   0.937   0.970   1.050
76    I         0.895   0.920   0.977   1.030   1.061   1.136   0.937   0.970   1.050
77    P         0.895   0.920   0.977   0.992   1.024   1.104   0.937   0.970   1.050
78    R         0.895   0.920   0.977   0.854   0.888   0.983   0.937   0.970   1.050
79    V         0.895   0.920   0.977   0.708   0.758   0.854   0.937   0.970   1.050
80    G         0.200  -0.037  -0.194   0.267  -0.041  -0.298   0.220  -0.130  -0.410
81    G         0.895   0.920   0.977   0.839   0.871   0.969   0.937   0.970   1.050
82    G         0.200   0.124  -0.185   0.267   0.176  -0.283   0.220   0.112  -0.396
83    G         0.895   0.920   0.977   0.839   0.871   0.969   0.937   0.970   1.050
84    T         0.895   0.920   0.977   0.954   0.993   1.070   0.937   0.970   1.050
85    G         0.200   0.328  -0.174   0.547   0.693  -0.041   0.220   0.389  -0.376
86    R         0.895   0.920   0.977   0.854   0.888   0.983   0.937   0.970   1.050
87    S         0.200  -0.037  -0.194   0.255  -0.069  -0.389   0.220  -0.130  -0.410
88    G         0.895   0.920   0.977   0.839   0.871   0.969   0.937   0.970   1.050
89    Q         0.895   0.920   0.977   1.047   1.080   1.152   0.937   0.970   1.050
90    G        -0.373  -0.314  -0.269  -0.798  -0.713  -0.616  -0.677  -0.584  -0.542
91    A         0.895   0.920   0.977   0.606   0.642   0.764   0.937   0.970   1.050
92    F         0.895   0.920   0.977   1.109   1.140   1.206   0.937   0.970   1.050
93    G         0.895   0.920   0.977   0.839   0.871   0.969   0.937   0.970   1.050
94    N         0.895   0.920   0.977   1.000   1.037   1.111   0.937   0.970   1.050
95    M         0.895   0.920   0.977   1.194   1.222   1.281   0.937   0.970   1.050
96    C         0.895   0.920   0.977   1.229   1.259   1.312   0.937   0.970   1.050
97    R         0.895   0.920   0.977   0.854   0.888   0.983   0.937   0.970   1.050
98    G        -0.373  -0.405  -0.274  -0.571  -0.651  -0.447  -0.677  -0.745  -0.552
99    G         0.895   0.920   0.977   0.839   0.871   0.969   0.937   0.970   1.050
100   R         0.895   0.920   0.977   0.854   0.888   0.983   0.937   0.970   1.050
101   M         0.895   0.920   0.977   1.194   1.222   1.281   0.937   0.970   1.050
102   F         0.895   0.920   0.977   1.109   1.140   1.206   0.937   0.970   1.050
103   A         0.895   0.920   0.977   0.606   0.642   0.764   0.937   0.970   1.050
104   P         0.895   0.920   0.977   0.992   1.024   1.104   0.937   0.970   1.050
105   T         0.895   0.920   0.977   0.954   0.993   1.070   0.937   0.970   1.050
106   K         0.895   0.920   0.977   0.754   0.791   0.894   0.937   0.970   1.050
107   T         0.200  -0.037  -0.194   0.404   0.117  -0.133   0.220  -0.130  -0.410
108   W         0.895   0.920   0.977   1.175   1.207   1.265   0.937   0.970   1.050
109   R         0.895   0.920   0.977   0.854   0.888   0.983   0.937   0.970   1.050
110   K         0.200   0.310  -0.171   0.181   0.311  -0.329   0.220   0.366  -0.372
111   W         0.895   0.920   0.977   1.175   1.207   1.265   0.937   0.970   1.050
112   N        -0.473  -0.364  -0.266  -0.445  -0.256  -0.151  -0.856  -0.673  -0.536
113   V         0.895   0.920   0.977   0.708   0.758   0.854   0.937   0.970   1.050
114   K         0.895   0.920   0.977   0.754   0.791   0.894   0.937   0.970   1.050
115   V         0.895   0.920   0.977   0.708   0.758   0.854   0.937   0.970   1.050
116   N         0.895   0.920   0.977   1.000   1.037   1.111   0.937   0.970   1.050
117   H        -0.971  -0.935  -0.971  -0.754  -0.688  -0.778  -1.125  -1.034  -1.046
118   N         0.200  -0.037  -0.194   0.426   0.116  -0.176   0.220  -0.130  -0.410
119   E         0.200  -0.037  -0.194   0.489   0.196  -0.061   0.220  -0.130  -0.410
120   K         0.895   0.920   0.977   0.754   0.791   0.894   0.937   0.970   1.050
121   R         0.895   0.920   0.977   0.854   0.888   0.983   0.937   0.970   1.050
122   Y         0.200  -0.037  -0.194   0.617   0.330   0.059   0.220  -0.130  -0.410
123   A         0.895   0.920   0.977   0.606   0.642   0.764   0.937   0.970   1.050
124   T        -0.160  -0.100  -0.201  -0.054   0.029  -0.145  -0.318  -0.229  -0.423
125   A         0.200   0.248  -0.170   0.033   0.093  -0.449   0.220   0.284  -0.370
126   S         0.895   0.920   0.977   0.858   0.903   0.985   0.937   0.970   1.050
127   A         0.895   0.920   0.977   0.606   0.642   0.764   0.937   0.970   1.050
128   I        -0.795  -0.956  -0.963  -0.627  -0.861  -0.963  -0.856  -1.037  -1.034
129   A         0.895   0.920   0.977   0.606   0.642   0.764   0.937   0.970   1.050
130   A         0.895   0.920   0.977   0.606   0.642   0.764   0.937   0.970   1.050
131   T         0.200   0.328  -0.174   0.298   0.453  -0.209   0.220   0.389  -0.376
132   A        -0.160  -0.100  -0.201  -0.451  -0.369  -0.507  -0.318  -0.229  -0.423
133   V         0.200  -0.037  -0.194   0.103  -0.216  -0.515   0.220  -0.130  -0.410
134   A        -1.218  -1.080  -0.989  -1.479  -1.309  -1.115  -1.394  -1.212  -1.068
135   S        -0.160  -0.326  -0.269  -0.159  -0.421  -0.347  -0.318  -0.606  -0.543
136   L         0.895   0.920   0.977   0.849   0.883   0.978   0.937   0.970   1.050
137   V        -0.373  -0.405  -0.274  -0.697  -0.761  -0.544  -0.677  -0.745  -0.552
138   L         0.200  -0.037  -0.194   0.321   0.048  -0.144   0.220  -0.130  -0.410
139   A         0.895   0.920   0.977   0.606   0.642   0.764   0.937   0.970   1.050
140   R         0.895   0.920   0.977   0.854   0.888   0.983   0.937   0.970   1.050
141   G         0.895   0.920   0.977   0.839   0.871   0.969   0.937   0.970   1.050
142   H         0.895   0.920   0.977   1.121   1.155   1.217   0.937   0.970   1.050
143   R         0.200  -0.037  -0.194   0.307   0.019  -0.204   0.220  -0.130  -0.410
144   V        -0.160  -0.100  -0.201  -0.294  -0.201  -0.338  -0.318  -0.229  -0.423
145   E         0.200  -0.037  -0.194   0.466   0.155  -0.139   0.220  -0.130  -0.410
146   K        -1.831  -1.753  -1.526  -1.789  -1.671  -1.343  -1.752  -1.654  -1.358
147   I        -0.473  -0.436  -0.280  -0.700  -0.658  -0.425  -0.856  -0.801  -0.562
148   P        -0.795  -0.757  -0.952  -0.687  -0.624  -1.048  -0.856  -0.780  -1.020
149   E         0.200   0.322  -0.175   0.466   0.605  -0.104   0.220   0.382  -0.379
150   I        -1.218  -1.035  -0.988  -1.419  -1.160  -1.079  -1.394  -1.148  -1.066
151   P         0.895   0.920   0.977   0.992   1.024   1.104   0.937   0.970   1.050
152   L         0.895   0.920   0.977   0.849   0.883   0.978   0.937   0.970   1.050
153   V         0.895   0.920   0.977   0.708   0.758   0.854   0.937   0.970   1.050
154   V         0.895   0.920   0.977   0.708   0.758   0.854   0.937   0.970   1.050
155   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
156   S        -0.795  -0.658  -0.935  -0.699  -0.515  -0.959  -0.856  -0.684  -0.999
157   T        -2.022  -1.971  -1.922  -1.708  -1.726  -1.674  -1.752  -1.691  -1.514
158   D        -0.971  -0.914  -0.981  -0.918  -0.945  -0.946  -1.125  -1.079  -1.059
159   L        -1.716  -1.683  -1.516  -1.654  -1.560  -1.335  -1.663  -1.592  -1.348
160   E        -0.971  -1.090  -0.985  -0.799  -0.958  -0.841  -1.125  -1.224  -1.064
161   S         0.200  -0.037  -0.194   0.283  -0.017  -0.291   0.220  -0.130  -0.410
162   I        -1.716  -1.683  -1.516  -1.663  -1.640  -1.388  -1.663  -1.592  -1.348
163   Q        -1.525  -1.556  -1.510  -1.303  -1.347  -1.306  -1.483  -1.496  -1.344
164   K         0.895   0.920   0.977   0.754   0.791   0.894   0.937   0.970   1.050
165   T         0.895   0.920   0.977   0.954   0.993   1.070   0.937   0.970   1.050
166   K         0.200  -0.037  -0.194   0.150  -0.182  -0.476   0.220  -0.130  -0.410
167   E        -0.971  -1.108  -0.988  -0.738  -0.910  -0.753  -1.125  -1.250  -1.068
168   A         0.895   0.920   0.977   0.606   0.642   0.764   0.937   0.970   1.050
169   V        -0.467  -0.601  -0.933  -0.410  -0.598  -1.011  -0.408  -0.600  -0.996
170   A         0.895   0.920   0.977   0.606   0.642   0.764   0.937   0.970   1.050
171   A        -1.218  -1.130  -1.001  -1.678  -1.532  -1.321  -1.394  -1.286  -1.082
172   L         0.895   0.920   0.977   0.849   0.883   0.978   0.937   0.970   1.050
173   K         0.895   0.920   0.977   0.754   0.791   0.894   0.937   0.970   1.050
174   A        -0.160  -0.100  -0.201  -0.391  -0.312  -0.415  -0.318  -0.229  -0.423
175   V        -0.160  -0.100  -0.201  -0.294  -0.201  -0.338  -0.318  -0.229  -0.423
176   G        -0.160  -0.100  -0.201  -0.244  -0.163  -0.356  -0.318  -0.229  -0.423
177   A         0.895   0.920   0.977   0.606   0.642   0.764   0.937   0.970   1.050
178   H        -1.087  -1.103  -0.987  -0.827  -0.897  -0.782  -1.214  -1.233  -1.067
179   S        -1.831  -1.721  -1.528  -2.128  -1.992  -1.705  -1.752  -1.624  -1.360
180   D         0.895   0.920   0.977   1.120   1.150   1.216   0.937   0.970   1.050
181   L        -0.160   0.004  -0.210  -0.347  -0.100  -0.436  -0.318  -0.066  -0.439
182   L        -2.138  -2.182  -1.918  -2.058  -2.109  -1.792  -1.842  -1.832  -1.512
183   K         0.200   0.124  -0.185   0.181   0.093  -0.354   0.220   0.112  -0.396
184   V         0.200  -0.037  -0.194   0.103  -0.216  -0.515   0.220  -0.130  -0.410
185   L        -2.138  -2.134  -1.928  -2.204  -2.273  -1.953  -1.842  -1.809  -1.519
186   K        -0.795  -0.956  -0.963  -0.840  -1.097  -1.138  -0.856  -1.037  -1.034
187   S         0.895   0.920   0.977   0.858   0.903   0.985   0.937   0.970   1.050
188   K        -0.160  -0.100  -0.201  -0.300  -0.216  -0.381  -0.318  -0.229  -0.423
189   K         0.200   0.124  -0.185   0.194   0.111  -0.311   0.220   0.112  -0.396
190   L        -0.467  -0.430  -0.925  -0.217  -0.189  -0.758  -0.408  -0.368  -0.985
191   R         0.895   0.920   0.977   0.854   0.888   0.983   0.937   0.970   1.050
192   A         0.895   0.920   0.977   0.606   0.642   0.764   0.937   0.970   1.050
193   G         0.895   0.920   0.977   0.839   0.871   0.969   0.937   0.970   1.050
194   K         0.895   0.920   0.977   0.754   0.791   0.894   0.937   0.970   1.050
195   G         0.895   0.920   0.977   0.839   0.871   0.969   0.937   0.970   1.050
196   K         0.895   0.920   0.977   0.754   0.791   0.894   0.937   0.970   1.050
197   Y        -0.373  -0.221  -0.243  -0.420  -0.207  -0.226  -0.677  -0.425  -0.495
198   R         0.895   0.920   0.977   0.854   0.888   0.983   0.937   0.970   1.050
199   N        -0.795  -0.893  -0.959  -0.571  -0.668  -0.812  -0.856  -0.954  -1.029
200   R         0.895   0.920   0.977   0.854   0.888   0.983   0.937   0.970   1.050
201   R         0.895   0.920   0.977   0.854   0.888   0.983   0.937   0.970   1.050
202   W        -1.293  -1.211  -1.015  -1.032  -0.926  -0.673  -1.483  -1.371  -1.099
203   T        -0.795  -0.956  -0.963  -0.700  -0.925  -1.016  -0.856  -1.037  -1.034
204   Q         0.895   0.920   0.977   1.047   1.080   1.152   0.937   0.970   1.050
205   R         0.895   0.920   0.977   0.854   0.888   0.983   0.937   0.970   1.050
206   R         0.895   0.920   0.977   0.854   0.888   0.983   0.937   0.970   1.050
207   G         0.895   0.920   0.977   0.839   0.871   0.969   0.937   0.970   1.050
208   P         0.895   0.920   0.977   0.992   1.024   1.104   0.937   0.970   1.050
209   L         0.895   0.920   0.977   0.849   0.883   0.978   0.937   0.970   1.050
210   V         0.895   0.920   0.977   0.708   0.758   0.854   0.937   0.970   1.050
211   V         0.895   0.920   0.977   0.708   0.758   0.854   0.937   0.970   1.050
212   Y        -0.160  -0.100  -0.201   0.165   0.243   0.046  -0.318  -0.229  -0.423
213   A        -1.218  -1.165  -0.987  -1.545  -1.437  -1.141  -1.394  -1.320  -1.067
214   E        -0.795  -0.893  -0.959  -0.550  -0.722  -0.896  -0.856  -0.954  -1.029
215   D        -0.467  -0.770  -0.950   0.023  -0.371  -0.680  -0.408  -0.797  -1.018
216   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
217   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
218   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
219   N        -1.394  -1.442  -1.510  -1.212  -1.391  -1.517  -1.304  -1.381  -1.344
220   G         0.200  -0.037  -0.194   0.301   0.019  -0.185   0.220  -0.130  -0.410
221   I        -0.795  -0.848  -0.978  -0.605  -0.777  -0.997  -0.856  -0.980  -1.056
222   V        -0.467  -0.601  -0.933  -0.394  -0.558  -0.968  -0.408  -0.600  -0.996
223   K         0.895   0.920   0.977   0.754   0.791   0.894   0.937   0.970   1.050
224   A         0.200  -0.037  -0.194   0.030  -0.277  -0.495   0.220  -0.130  -0.410
225   L        -0.473  -0.366  -0.263  -0.548  -0.346  -0.235  -0.856  -0.675  -0.532
226   R         0.895   0.920   0.977   0.854   0.888   0.983   0.937   0.970   1.050
227   N         0.895   0.920   0.977   1.000   1.037   1.111   0.937   0.970   1.050
228   V        -0.473  -0.432  -0.277  -0.753  -0.644  -0.409  -0.856  -0.794  -0.556
229   P         0.895   0.920   0.977   0.992   1.024   1.104   0.937   0.970   1.050
230   G         0.895   0.920   0.977   0.839   0.871   0.969   0.937   0.970   1.050
231   V         0.895   0.920   0.977   0.708   0.758   0.854   0.937   0.970   1.050
232   E         0.895   0.920   0.977   1.038   1.069   1.144   0.937   0.970   1.050
233   T        -0.160  -0.100  -0.201  -0.054   0.029  -0.145  -0.318  -0.229  -0.423
234   A        -1.716  -1.728  -1.523  -1.991  -1.936  -1.564  -1.663  -1.640  -1.356
235   N        -1.640  -1.600  -1.521  -1.367  -1.344  -1.229  -1.573  -1.532  -1.354
236   V         0.895   0.920   0.977   0.708   0.758   0.854   0.937   0.970   1.050
237   A        -2.138  -2.061  -1.929  -2.194  -2.012  -1.821  -1.842  -1.743  -1.520
238   S        -1.831  -1.751  -1.525  -1.866  -1.796  -1.493  -1.752  -1.653  -1.357
239   L         0.895   0.920   0.977   0.849   0.883   0.978   0.937   0.970   1.050
240   N        -0.373  -0.238  -0.249  -0.430  -0.205  -0.288  -0.677  -0.455  -0.507
241   L         0.895   0.920   0.977   0.849   0.883   0.978   0.937   0.970   1.050
242   L         0.895   0.920   0.977   0.849   0.883   0.978   0.937   0.970   1.050
243   Q         0.895   0.920   0.977   1.047   1.080   1.152   0.937   0.970   1.050
244   L         0.895   0.920   0.977   0.849   0.883   0.978   0.937   0.970   1.050
245   A         0.895   0.920   0.977   0.606   0.642   0.764   0.937   0.970   1.050
246   P         0.895   0.920   0.977   0.992   1.024   1.104   0.937   0.970   1.050
247   G         0.895   0.920   0.977   0.839   0.871   0.969   0.937   0.970   1.050
248   A        -0.971  -1.043  -0.992  -1.296  -1.387  -1.241  -1.125  -1.199  -1.072
249   H         0.895   0.920   0.977   1.121   1.155   1.217   0.937   0.970   1.050
250   L         0.895   0.920   0.977   0.849   0.883   0.978   0.937   0.970   1.050
251   G         0.895   0.920   0.977   0.839   0.871   0.969   0.937   0.970   1.050
252   R         0.895   0.920   0.977   0.854   0.888   0.983   0.937   0.970   1.050
253   F         0.895   0.920   0.977   1.109   1.140   1.206   0.937   0.970   1.050
254   V        -0.160  -0.252  -0.263  -0.294  -0.422  -0.423  -0.318  -0.479  -0.531
255   I         0.200  -0.037  -0.194   0.440   0.115  -0.206   0.220  -0.130  -0.410
256   W         0.895   0.920   0.977   1.175   1.207   1.265   0.937   0.970   1.050
257   T         0.895   0.920   0.977   0.954   0.993   1.070   0.937   0.970   1.050
258   E        -1.716  -1.762  -1.519  -1.589  -1.664  -1.336  -1.663  -1.662  -1.352
259   A        -1.293  -1.230  -1.015  -1.700  -1.626  -1.267  -1.483  -1.394  -1.098
260   A         0.895   0.920   0.977   0.606   0.642   0.764   0.937   0.970   1.050
261   F         0.200  -0.037  -0.194   0.557   0.260  -0.013   0.220  -0.130  -0.410
262   T        -2.868  -2.774  -2.552  -2.587  -2.512  -2.226  -2.111  -2.015  -1.714
263   K        -1.716  -1.729  -1.524  -1.832  -1.792  -1.488  -1.663  -1.631  -1.357
264   L         0.895   0.920   0.977   0.849   0.883   0.978   0.937   0.970   1.050
265   D         0.895   0.920   0.977   1.120   1.150   1.216   0.937   0.970   1.050
266   Q        -1.525  -1.653  -1.515  -1.428  -1.632  -1.435  -1.483  -1.561  -1.348
267   V        -0.160  -0.141  -0.250  -0.294  -0.258  -0.408  -0.318  -0.295  -0.509
268   W        -1.218  -1.168  -0.992  -0.893  -0.838  -0.618  -1.394  -1.324  -1.072
269   G         0.200  -0.037  -0.194   0.290  -0.001  -0.220   0.220  -0.130  -0.410
270   S         0.895   0.920   0.977   0.858   0.903   0.985   0.937   0.970   1.050
271   E        -1.176  -1.110  -0.991  -1.014  -0.936  -0.782  -1.332  -1.241  -1.069
272   T        -0.423  -0.406  -0.278  -0.566  -0.557  -0.380  -0.765  -0.747  -0.557
273   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
274   V        -0.898  -0.837  -0.962  -1.064  -0.969  -1.193  -0.992  -0.895  -1.033
275   A        -0.225  -0.133  -0.234  -0.572  -0.427  -0.598  -0.425  -0.282  -0.480
276   S        -0.225  -0.218  -0.230  -0.245  -0.238  -0.264  -0.425  -0.421  -0.474
277   S        -2.211  -2.163  -1.941  -2.235  -2.214  -1.931  -1.899  -1.825  -1.528
278   K         0.895   0.920   0.977   0.754   0.791   0.894   0.937   0.970   1.050
279   V        -2.138  -1.923  -1.925  -2.242  -1.934  -1.979  -1.842  -1.634  -1.517
280   G        -0.160  -0.100  -0.201  -0.174  -0.096  -0.248  -0.318  -0.229  -0.423
281   Y         0.200  -0.037  -0.194   0.617   0.330   0.059   0.220  -0.130  -0.410
282   T        -2.138  -2.135  -1.928  -1.907  -1.885  -1.669  -1.842  -1.809  -1.519
283   L         0.895   0.920   0.977   0.849   0.883   0.978   0.937   0.970   1.050
284   P         0.895   0.920   0.977   0.992   1.024   1.104   0.937   0.970   1.050
285   S        -1.087  -1.150  -0.996  -1.191  -1.379  -1.144  -1.214  -1.299  -1.077
286   H         0.200   0.328  -0.174   0.461   0.603  -0.029   0.220   0.389  -0.376
287   I         0.200  -0.037  -0.194   0.440   0.115  -0.206   0.220  -0.130  -0.410
288   I        -0.795  -0.938  -0.978  -0.627  -0.880  -1.016  -0.856  -1.040  -1.056
289   S        -0.373  -0.414  -0.280  -0.669  -0.800  -0.605  -0.677  -0.762  -0.562
290   T        -0.971  -1.046  -0.978  -0.847  -0.896  -0.826  -1.125  -1.161  -1.054
291   S        -1.218  -1.031  -0.994  -1.544  -1.287  -1.188  -1.394  -1.145  -1.074
292   D         0.895   0.920   0.977   1.120   1.150   1.216   0.937   0.970   1.050
293   V        -0.467  -0.580  -0.935  -0.410  -0.577  -1.015  -0.408  -0.578  -0.999
294   T         0.200   0.124  -0.185   0.382   0.298  -0.190   0.220   0.112  -0.396
295   R         0.895   0.920   0.977   0.854   0.888   0.983   0.937   0.970   1.050
296   I        -0.473  -0.407  -0.276  -0.641  -0.551  -0.339  -0.856  -0.749  -0.555
297   I         0.895   0.920   0.977   1.030   1.061   1.136   0.937   0.970   1.050
298   N         0.200   0.124  -0.185   0.451   0.368  -0.081   0.220   0.112  -0.396
299   S         0.895   0.920   0.977   0.858   0.903   0.985   0.937   0.970   1.050
300   S        -2.138  -2.033  -1.921  -2.012  -1.839  -1.674  -1.842  -1.719  -1.514
301   E         0.895   0.920   0.977   1.038   1.069   1.144   0.937   0.970   1.050
302   I        -0.160  -0.023  -0.208  -0.068   0.137  -0.238  -0.318  -0.107  -0.436
303   Q         0.895   0.920   0.977   1.047   1.080   1.152   0.937   0.970   1.050
304   S        -0.373  -0.231  -0.249  -0.669  -0.403  -0.516  -0.677  -0.443  -0.507
305   A        -1.218  -1.100  -0.996  -1.517  -1.321  -1.188  -1.394  -1.248  -1.076
306   I        -0.971  -0.906  -0.976  -1.164  -1.112  -1.078  -1.125  -1.077  -1.056
307   R        -0.373  -0.356  -0.269  -0.605  -0.600  -0.485  -0.677  -0.659  -0.542
308   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
309   P        -0.373  -0.288  -0.259  -0.541  -0.397  -0.437  -0.677  -0.539  -0.524
310   A         0.200  -0.037  -0.194   0.019  -0.297  -0.534   0.220  -0.130  -0.410
311   G         0.200   0.124  -0.185   0.254   0.158  -0.326   0.220   0.112  -0.396
312   Q        -1.640  -1.738  -1.518  -1.310  -1.430  -1.142  -1.573  -1.637  -1.351
313   A        -2.138  -2.032  -1.919  -2.209  -2.072  -1.845  -1.842  -1.716  -1.513
314   T        -1.947  -2.030  -1.925  -1.688  -1.852  -1.706  -1.663  -1.718  -1.516
315   Q        -1.394  -1.593  -1.512  -1.104  -1.385  -1.312  -1.304  -1.490  -1.344
316   K         0.895   0.920   0.977   0.754   0.791   0.894   0.937   0.970   1.050
317   R         0.145   0.227  -0.191   0.203   0.304  -0.324   0.143   0.255  -0.406
318   T        -1.176  -1.191  -0.998  -1.345  -1.405  -1.135  -1.332  -1.347  -1.080
319   H        -0.467  -0.770  -0.950   0.036  -0.353  -0.646  -0.408  -0.797  -1.018
320   V         0.200   0.124  -0.185   0.158   0.089  -0.316   0.220   0.112  -0.396
321   L        -1.027  -1.025  -0.981  -1.034  -0.991  -0.935  -1.214  -1.171  -1.060
322   K         0.895   0.920   0.977   0.754   0.791   0.894   0.937   0.970   1.050
323   K         0.200   0.124  -0.185   0.226   0.151  -0.207   0.220   0.112  -0.396
324   N         0.895   0.920   0.977   1.000   1.037   1.111   0.937   0.970   1.050
325   P         0.895   0.920   0.977   0.992   1.024   1.104   0.937   0.970   1.050
326   L         0.895   0.920   0.977   0.849   0.883   0.978   0.937   0.970   1.050
327   K         0.200  -0.037  -0.194   0.181  -0.124  -0.368   0.220  -0.130  -0.410
328   N         0.895   0.920   0.977   1.000   1.037   1.111   0.937   0.970   1.050
329   K         0.895   0.920   0.977   0.754   0.791   0.894   0.937   0.970   1.050
330   Q        -0.160  -0.100  -0.201  -0.077   0.006  -0.249  -0.318  -0.229  -0.423
331   V         0.200   0.124  -0.185   0.159   0.091  -0.312   0.220   0.112  -0.396
332   L         0.895   0.920   0.977   0.849   0.883   0.978   0.937   0.970   1.050
333   L        -0.467  -0.392  -0.926  -0.327  -0.235  -1.063  -0.408  -0.311  -0.987
334   R         0.895   0.920   0.977   0.854   0.888   0.983   0.937   0.970   1.050
335   L         0.895   0.920   0.977   0.849   0.883   0.978   0.937   0.970   1.050
336   N         0.895   0.920   0.977   1.000   1.037   1.111   0.937   0.970   1.050
337   P         0.895   0.920   0.977   0.992   1.024   1.104   0.937   0.970   1.050
338   Y         0.895   0.920   0.977   1.160   1.194   1.251   0.937   0.970   1.050
339   A         0.200   0.124  -0.185   0.033  -0.054  -0.474   0.220   0.112  -0.396
340   K         0.200  -0.037  -0.194   0.150  -0.182  -0.476   0.220  -0.130  -0.410
341   V        -1.218  -1.210  -1.012  -1.662  -1.602  -1.275  -1.394  -1.370  -1.095
342   F        -0.373  -0.292  -0.260  -0.190  -0.076  -0.066  -0.677  -0.547  -0.526
343   A        -0.795  -0.658  -0.935  -1.031  -0.853  -1.211  -0.856  -0.684  -0.999
344   A        -0.467  -0.770  -0.950  -0.525  -0.936  -1.148  -0.408  -0.797  -1.018
345   E        -0.795  -0.824  -0.953  -0.543  -0.586  -0.852  -0.856  -0.873  -1.021
346   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
347   K         0.895   0.920   0.977   0.754   0.791   0.894   0.937   0.970   1.050
348   L        -0.467  -0.334  -0.905  -0.287  -0.128  -0.916  -0.408  -0.240  -0.960
349   G        -0.160  -0.100  -0.201  -0.174  -0.096  -0.248  -0.318  -0.229  -0.423
350   S        -0.467  -0.662  -0.930  -0.243  -0.483  -0.851  -0.408  -0.669  -0.992
351   K        -2.138  -2.045  -1.928  -2.179  -1.984  -1.802  -1.842  -1.736  -1.519
352   K         0.895   0.920   0.977   0.754   0.791   0.894   0.937   0.970   1.050
353   A        -1.831  -1.746  -1.525  -2.039  -1.832  -1.555  -1.752  -1.648  -1.358
354   E        -2.022  -1.801  -1.907  -1.710  -1.446  -1.590  -1.752  -1.553  -1.503
355   K        -0.971  -1.058  -0.978  -1.048  -1.158  -1.022  -1.125  -1.178  -1.054
356   T        -1.525  -1.554  -1.501  -1.700  -1.761  -1.608  -1.483  -1.494  -1.336
357   G        -2.445  -2.337  -2.259  -2.435  -2.292  -2.101  -1.932  -1.829  -1.628
358   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
359   T        -1.753  -1.626  -1.526  -1.919  -1.758  -1.598  -1.685  -1.535  -1.358
360   K         0.078  -0.180  -0.224   0.065  -0.280  -0.332   0.048  -0.358  -0.463
361   P        -0.691  -0.992  -0.985  -0.401  -0.867  -0.886  -0.693  -1.091  -1.062
362   A        -1.008  -1.164  -0.997  -1.235  -1.519  -1.307  -1.138  -1.310  -1.078
363   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
364   -        -1.119  -1.141  -0.996  -1.327  -1.337  -1.099  -1.282  -1.281  -1.075
365   A        -1.087  -0.944  -0.960  -1.339  -1.140  -1.126  -1.214  -1.022  -1.031
366   V        -1.831  -1.718  -1.527  -1.949  -1.779  -1.495  -1.752  -1.622  -1.359
367   F         0.200   0.322  -0.175   0.507   0.651  -0.141   0.220   0.382  -0.379
368   A        -2.445  -2.413  -2.259  -2.322  -2.288  -2.033  -1.932  -1.878  -1.629
369   E        -1.947  -1.951  -1.917  -1.490  -1.548  -1.474  -1.663  -1.663  -1.512
370   T        -1.525  -1.653  -1.515  -1.555  -1.701  -1.462  -1.483  -1.561  -1.348
371   L         0.895   0.920   0.977   0.849   0.883   0.978   0.937   0.970   1.050
372   K        -0.795  -0.956  -0.963  -0.727  -0.919  -0.891  -0.856  -1.037  -1.034
373   H        -1.119  -1.167  -1.008  -0.869  -0.937  -0.729  -1.282  -1.318  -1.090
374   D        -0.971  -1.046  -0.978  -0.764  -0.832  -0.750  -1.125  -1.161  -1.054
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P49626
Output conservation file - output/P49626
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
