1     M         1.151   1.171   1.219   1.290   1.324   1.389   1.240   1.265   1.330
2     L        -1.561  -1.510  -1.494  -1.560  -1.495  -1.477  -1.294  -1.237  -1.165
3     I        -1.949  -1.839  -1.767  -1.766  -1.631  -1.523  -1.496  -1.395  -1.266
4     S        -1.667  -1.526  -1.515  -1.662  -1.470  -1.436  -1.395  -1.267  -1.183
5     S        -1.667  -1.638  -1.524  -1.664  -1.606  -1.441  -1.395  -1.350  -1.189
6     R        -0.540  -0.419  -0.413  -0.729  -0.540  -0.534  -0.787  -0.610  -0.609
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    I        -1.011  -0.919  -0.892  -1.078  -0.926  -0.915  -1.102  -0.986  -0.923
13    V        -1.387  -1.307  -1.237  -1.516  -1.404  -1.307  -1.282  -1.193  -1.079
14    R        -0.603  -0.570  -0.464  -0.904  -0.862  -0.679  -0.878  -0.826  -0.680
15    S        -2.013  -1.956  -1.783  -1.954  -1.852  -1.625  -1.540  -1.475  -1.276
16    S        -1.691  -1.668  -1.538  -1.761  -1.709  -1.525  -1.407  -1.369  -1.198
17    L         0.178   0.272   0.231  -0.015   0.138   0.065  -0.084   0.080  -0.032
18    V        -1.369  -1.292  -1.229  -1.532  -1.423  -1.313  -1.275  -1.190  -1.074
19    N        -2.013  -1.956  -1.783  -1.790  -1.699  -1.472  -1.540  -1.475  -1.276
20    V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
21    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
22    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
23    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
24    P        -1.369  -1.334  -1.245  -1.445  -1.391  -1.257  -1.275  -1.224  -1.087
25    L        -0.144  -0.001  -0.328  -0.140   0.053  -0.403  -0.216  -0.015  -0.489
26    R        -1.248  -1.180  -1.209  -1.197  -1.098  -1.188  -1.143  -1.062  -1.054
27    L        -1.369  -1.385  -1.241  -1.535  -1.579  -1.358  -1.275  -1.266  -1.084
28    S        -1.691  -1.605  -1.519  -1.676  -1.566  -1.416  -1.407  -1.316  -1.184
29    R        -0.725  -0.699  -0.823  -0.596  -0.569  -0.772  -0.746  -0.714  -0.843
30    C        -0.725  -0.588  -0.812  -0.717  -0.523  -0.841  -0.746  -0.569  -0.832
31    F        -1.369  -1.288  -1.236  -1.371  -1.229  -1.156  -1.275  -1.180  -1.080
32    T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
33    Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
34    A        -0.821  -0.654  -0.833  -0.961  -0.707  -0.967  -0.888  -0.678  -0.858
35    H        -1.385  -1.374  -1.239  -1.400  -1.365  -1.171  -1.294  -1.260  -1.083
36    R        -1.667  -1.657  -1.522  -1.660  -1.674  -1.466  -1.395  -1.365  -1.188
37    A        -0.821  -0.864  -0.852  -0.935  -0.976  -0.960  -0.888  -0.914  -0.878
38    C        -1.561  -1.471  -1.498  -1.291  -1.174  -1.213  -1.294  -1.202  -1.169
39    K        -1.385  -1.348  -1.237  -1.496  -1.446  -1.283  -1.294  -1.240  -1.081
40    E        -1.561  -1.587  -1.521  -1.414  -1.476  -1.406  -1.294  -1.305  -1.186
41    E        -1.949  -1.789  -1.763  -1.820  -1.564  -1.571  -1.496  -1.351  -1.263
42    E        -1.561  -1.553  -1.508  -1.287  -1.279  -1.228  -1.294  -1.276  -1.176
43    V        -1.949  -1.895  -1.768  -1.943  -1.849  -1.676  -1.496  -1.437  -1.266
44    N        -0.045  -0.122  -0.354   0.114   0.019  -0.354  -0.078  -0.184  -0.525
45    S        -1.279  -1.252  -1.213  -1.276  -1.247  -1.149  -1.192  -1.158  -1.060
46    P        -1.279  -1.165  -1.204  -1.282  -1.108  -1.133  -1.192  -1.057  -1.050
47    L        -1.387  -1.383  -1.258  -1.466  -1.474  -1.264  -1.282  -1.265  -1.097
48    S        -0.869  -0.865  -0.865  -0.879  -0.884  -0.848  -0.922  -0.915  -0.891
49    S        -1.387  -1.322  -1.237  -1.464  -1.377  -1.233  -1.282  -1.208  -1.079
50    A        -1.763  -1.693  -1.545  -1.650  -1.539  -1.343  -1.462  -1.387  -1.203
51    A        -1.011  -0.937  -0.884  -1.122  -1.030  -0.916  -1.102  -1.014  -0.915
52    E        -1.763  -1.693  -1.545  -1.778  -1.665  -1.461  -1.462  -1.387  -1.203
53    Q        -1.691  -1.590  -1.521  -1.548  -1.411  -1.324  -1.407  -1.304  -1.186
54    P        -2.013  -1.951  -1.783  -1.861  -1.776  -1.538  -1.540  -1.472  -1.276
55    E        -1.691  -1.633  -1.525  -1.703  -1.607  -1.451  -1.407  -1.341  -1.189
56    Q        -1.103  -1.147  -1.202  -0.991  -1.093  -1.164  -0.990  -1.034  -1.047
57    K        -1.667  -1.652  -1.522  -1.601  -1.552  -1.362  -1.395  -1.361  -1.187
58    Y        -1.103  -1.202  -1.224  -0.849  -1.003  -1.047  -0.990  -1.088  -1.068
59    T         1.151   1.171   1.219   1.211   1.239   1.315   1.240   1.265   1.330
60    H         1.151   1.171   1.219   1.322   1.350   1.418   1.240   1.265   1.330
61    F         1.151   1.171   1.219   1.165   1.196   1.272   1.240   1.265   1.330
62    G         1.151   1.171   1.219   1.092   1.126   1.205   1.240   1.265   1.330
63    S        -0.433  -0.336  -0.399  -0.605  -0.432  -0.491  -0.686  -0.540  -0.594
64    K        -0.045  -0.087  -0.349   0.082   0.026  -0.370  -0.078  -0.148  -0.519
65    T         0.539   0.472   0.290   0.661   0.575   0.279   0.530   0.422   0.078
66    V         1.151   1.171   1.219   1.122   1.152   1.232   1.240   1.265   1.330
67    L        -1.385  -1.394  -1.245  -1.401  -1.393  -1.179  -1.294  -1.274  -1.087
68    K        -0.313  -0.332  -0.411  -0.338  -0.398  -0.506  -0.483  -0.545  -0.612
69    S        -0.821  -0.801  -0.853  -0.878  -0.840  -0.945  -0.888  -0.846  -0.880
70    T        -0.821  -0.724  -0.833  -0.827  -0.666  -0.853  -0.888  -0.756  -0.857
71    K         1.151   1.171   1.219   1.153   1.193   1.261   1.240   1.265   1.330
72    Q        -0.045  -0.100  -0.351   0.126   0.045  -0.314  -0.078  -0.165  -0.522
73    K        -0.595  -0.768  -0.860  -0.437  -0.676  -0.847  -0.584  -0.793  -0.886
74    L         0.539   0.416   0.281   0.522   0.362   0.158   0.530   0.329   0.061
75    V         1.151   1.171   1.219   1.122   1.152   1.232   1.240   1.265   1.330
76    G        -0.313  -0.425  -0.419  -0.408  -0.577  -0.585  -0.483  -0.627  -0.624
77    D        -0.997  -0.956  -0.888  -1.121  -1.044  -0.923  -1.091  -1.028  -0.919
78    V         1.151   1.171   1.219   1.122   1.152   1.232   1.240   1.265   1.330
79    F         1.151   1.171   1.219   1.165   1.196   1.272   1.240   1.265   1.330
80    S         0.539   0.416   0.281   0.511   0.352   0.152   0.530   0.329   0.061
81    S         1.151   1.171   1.219   1.047   1.077   1.163   1.240   1.265   1.330
82    V         1.151   1.171   1.219   1.122   1.152   1.232   1.240   1.265   1.330
83    A         1.151   1.171   1.219   1.110   1.130   1.221   1.240   1.265   1.330
84    N        -0.595  -0.706  -0.841  -0.548  -0.713  -0.910  -0.584  -0.724  -0.864
85    R        -0.821  -0.812  -0.853  -0.824  -0.808  -0.883  -0.888  -0.861  -0.879
86    Y         1.151   1.171   1.219   1.266   1.299   1.366   1.240   1.265   1.330
87    D         1.151   1.171   1.219   1.120   1.154   1.230   1.240   1.265   1.330
88    L        -1.279  -1.351  -1.236  -1.325  -1.414  -1.243  -1.192  -1.234  -1.079
89    M         1.151   1.171   1.219   1.290   1.324   1.389   1.240   1.265   1.330
90    N         1.151   1.171   1.219   1.188   1.222   1.293   1.240   1.265   1.330
91    D         1.151   1.171   1.219   1.120   1.154   1.230   1.240   1.265   1.330
92    V        -0.045  -0.229  -0.374   0.017  -0.256  -0.517  -0.078  -0.337  -0.554
93    M         1.151   1.171   1.219   1.290   1.324   1.389   1.240   1.265   1.330
94    S         1.151   1.171   1.219   1.047   1.077   1.163   1.240   1.265   1.330
95    L        -0.313  -0.305  -0.412  -0.399  -0.423  -0.523  -0.483  -0.501  -0.614
96    G         1.151   1.171   1.219   1.092   1.126   1.205   1.240   1.265   1.330
97    I        -0.045  -0.091  -0.347   0.102   0.050  -0.318  -0.078  -0.153  -0.516
98    H         1.151   1.171   1.219   1.322   1.350   1.418   1.240   1.265   1.330
99    R         1.151   1.171   1.219   1.195   1.222   1.300   1.240   1.265   1.330
100   L        -0.313  -0.289  -0.394  -0.395  -0.393  -0.485  -0.483  -0.471  -0.590
101   W         1.151   1.171   1.219   1.391   1.421   1.482   1.240   1.265   1.330
102   K         1.151   1.171   1.219   1.153   1.193   1.261   1.240   1.265   1.330
103   D        -0.595  -0.551  -0.813  -0.468  -0.412  -0.795  -0.584  -0.530  -0.832
104   H        -0.045  -0.122  -0.354   0.242   0.135  -0.255  -0.078  -0.184  -0.525
105   F         1.151   1.171   1.219   1.165   1.196   1.272   1.240   1.265   1.330
106   I         0.075   0.054   0.150  -0.149  -0.208  -0.051  -0.280  -0.333  -0.189
107   N        -1.103  -1.141  -1.194  -0.893  -0.992  -1.052  -0.990  -1.028  -1.039
108   K        -0.891  -0.943  -0.879  -0.943  -1.014  -0.911  -0.990  -1.019  -0.909
109   L         1.151   1.171   1.219   1.061   1.091   1.175   1.240   1.265   1.330
110   D         0.075   0.054   0.150  -0.140  -0.182  -0.025  -0.280  -0.333  -0.189
111   A         0.075   0.054   0.150  -0.113  -0.164   0.014  -0.280  -0.333  -0.189
112   G         1.151   1.171   1.219   1.092   1.126   1.205   1.240   1.265   1.330
113   K        -0.926  -1.000  -0.902  -0.900  -1.000  -0.861  -1.010  -1.070  -0.932
114   R         0.484   0.327   0.247   0.566   0.324   0.158   0.446   0.178  -0.003
115   P         0.484   0.453   0.264   0.633   0.580   0.267   0.446   0.390   0.031
116   N        -0.433  -0.492  -0.427  -0.601  -0.674  -0.586  -0.686  -0.734  -0.636
117   S        -0.045  -0.117  -0.346  -0.033  -0.135  -0.473  -0.078  -0.186  -0.515
118   T        -0.313  -0.356  -0.409  -0.321  -0.412  -0.509  -0.483  -0.549  -0.610
119   T        -1.561  -1.556  -1.513  -1.383  -1.421  -1.344  -1.294  -1.278  -1.180
120   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
121   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
122   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
123   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
124   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
125   P         0.539   0.538   0.296   0.726   0.723   0.383   0.530   0.526   0.090
126   L        -0.045  -0.229  -0.374   0.024  -0.213  -0.407  -0.078  -0.337  -0.554
127   N        -1.667  -1.622  -1.520  -1.523  -1.446  -1.332  -1.395  -1.337  -1.186
128   F         0.237   0.142   0.169   0.176   0.002   0.018   0.024  -0.160  -0.152
129   I         0.075   0.160   0.195  -0.213  -0.063  -0.014  -0.280  -0.127  -0.102
130   D         1.151   1.171   1.219   1.120   1.154   1.230   1.240   1.265   1.330
131   V         0.539   0.416   0.281   0.577   0.414   0.194   0.530   0.329   0.061
132   A         1.151   1.171   1.219   1.110   1.130   1.221   1.240   1.265   1.330
133   G         1.151   1.171   1.219   1.092   1.126   1.205   1.240   1.265   1.330
134   G         1.151   1.171   1.219   1.092   1.126   1.205   1.240   1.265   1.330
135   S         0.024   0.058   0.155  -0.268  -0.201  -0.038  -0.382  -0.325  -0.179
136   G         1.151   1.171   1.219   1.092   1.126   1.205   1.240   1.265   1.330
137   D         1.151   1.171   1.219   1.120   1.154   1.230   1.240   1.265   1.330
138   I         1.151   1.171   1.219   1.149   1.181   1.257   1.240   1.265   1.330
139   A         1.151   1.171   1.219   1.110   1.130   1.221   1.240   1.265   1.330
140   F         1.151   1.171   1.219   1.165   1.196   1.272   1.240   1.265   1.330
141   G         0.075   0.054   0.150  -0.160  -0.204  -0.037  -0.280  -0.333  -0.189
142   L        -0.313  -0.446  -0.433  -0.405  -0.593  -0.559  -0.483  -0.660  -0.642
143   L         1.151   1.171   1.219   1.061   1.091   1.175   1.240   1.265   1.330
144   D        -0.595  -0.721  -0.838  -0.442  -0.610  -0.785  -0.584  -0.740  -0.861
145   H        -0.595  -0.653  -0.812  -0.252  -0.349  -0.603  -0.584  -0.659  -0.831
146   A         1.151   1.171   1.219   1.110   1.130   1.221   1.240   1.265   1.330
147   E        -0.595  -0.768  -0.860  -0.384  -0.618  -0.775  -0.584  -0.793  -0.886
148   S        -1.949  -1.917  -1.778  -1.789  -1.746  -1.551  -1.496  -1.452  -1.273
149   K        -0.595  -0.768  -0.860  -0.431  -0.681  -0.836  -0.584  -0.793  -0.886
150   F        -0.997  -0.981  -0.901  -0.982  -0.956  -0.812  -1.091  -1.060  -0.932
151   G        -0.313  -0.185  -0.354  -0.328  -0.141  -0.372  -0.483  -0.292  -0.528
152   D         0.539   0.416   0.281   0.580   0.424   0.207   0.530   0.329   0.061
153   T        -0.997  -1.037  -0.898  -1.033  -1.085  -0.877  -1.091  -1.110  -0.930
154   E        -1.561  -1.597  -1.529  -1.427  -1.508  -1.430  -1.294  -1.312  -1.192
155   S        -0.045  -0.229  -0.374  -0.031  -0.289  -0.513  -0.078  -0.337  -0.554
156   T        -0.821  -0.824  -0.877  -0.747  -0.786  -0.845  -0.888  -0.905  -0.908
157   M         0.237   0.142   0.169   0.289   0.106   0.101   0.024  -0.160  -0.152
158   D        -0.821  -0.757  -0.847  -0.751  -0.649  -0.777  -0.888  -0.795  -0.873
159   I         0.024   0.050   0.150  -0.260  -0.218  -0.050  -0.382  -0.340  -0.189
160   V        -0.433  -0.501  -0.431  -0.648  -0.754  -0.636  -0.686  -0.749  -0.642
161   D         1.151   1.171   1.219   1.120   1.154   1.230   1.240   1.265   1.330
162   I         1.151   1.171   1.219   1.149   1.181   1.257   1.240   1.265   1.330
163   N         1.151   1.171   1.219   1.188   1.222   1.293   1.240   1.265   1.330
164   P         0.539   0.634   0.308   0.702   0.816   0.345   0.530   0.670   0.111
165   D        -0.045  -0.172  -0.364   0.037  -0.143  -0.450  -0.078  -0.259  -0.540
166   M         1.151   1.171   1.219   1.290   1.324   1.389   1.240   1.265   1.330
167   L         1.151   1.171   1.219   1.061   1.091   1.175   1.240   1.265   1.330
168   K        -0.540  -0.568  -0.471  -0.761  -0.841  -0.693  -0.787  -0.826  -0.691
169   E         0.237   0.142   0.169   0.183   0.006   0.015   0.024  -0.160  -0.152
170   G         1.151   1.171   1.219   1.092   1.126   1.205   1.240   1.265   1.330
171   E        -0.045  -0.229  -0.374   0.083  -0.178  -0.451  -0.078  -0.337  -0.554
172   K        -1.103  -1.155  -1.215  -0.897  -0.968  -1.061  -0.990  -1.042  -1.059
173   R         1.151   1.171   1.219   1.195   1.222   1.300   1.240   1.265   1.330
174   A        -0.540  -0.540  -0.460  -0.775  -0.814  -0.676  -0.787  -0.789  -0.676
175   M        -0.891  -0.876  -0.866  -0.864  -0.857  -0.810  -0.990  -0.953  -0.895
176   E        -1.279  -1.296  -1.229  -1.293  -1.339  -1.249  -1.192  -1.194  -1.074
177   Q        -1.385  -1.327  -1.237  -1.318  -1.255  -1.093  -1.294  -1.224  -1.081
178   G        -0.609  -0.527  -0.457  -0.785  -0.631  -0.546  -0.888  -0.772  -0.672
179   K        -1.279  -1.353  -1.246  -1.108  -1.213  -1.059  -1.192  -1.236  -1.088
180   Y         0.338   0.311   0.209   0.439   0.397   0.190   0.202   0.149  -0.074
181   F        -1.279  -1.259  -1.221  -1.229  -1.220  -1.178  -1.192  -1.158  -1.067
182   K        -1.103  -1.162  -1.205  -0.921  -1.009  -1.114  -0.990  -1.048  -1.050
183   D        -0.821  -0.860  -0.871  -0.862  -0.924  -0.922  -0.888  -0.929  -0.902
184   P        -0.821  -0.911  -0.874  -0.773  -0.917  -0.898  -0.888  -0.966  -0.903
185   R         0.539   0.416   0.281   0.645   0.472   0.245   0.530   0.329   0.061
186   V        -0.045  -0.172  -0.364   0.024  -0.162  -0.482  -0.078  -0.259  -0.540
187   R        -1.561  -1.585  -1.523  -1.397  -1.468  -1.382  -1.294  -1.303  -1.187
188   F         1.151   1.171   1.219   1.165   1.196   1.272   1.240   1.265   1.330
189   L        -0.045  -0.046  -0.322   0.002  -0.005  -0.379  -0.078  -0.084  -0.480
190   V         0.237   0.142   0.169   0.145  -0.023   0.003   0.024  -0.160  -0.152
191   S        -0.045  -0.100  -0.351   0.172   0.083  -0.347  -0.078  -0.165  -0.522
192   N         1.151   1.171   1.219   1.188   1.222   1.293   1.240   1.265   1.330
193   G         0.075   0.054   0.150  -0.206  -0.267  -0.097  -0.280  -0.333  -0.189
194   E         1.151   1.171   1.219   1.180   1.214   1.286   1.240   1.265   1.330
195   K        -1.103  -1.147  -1.202  -0.924  -1.014  -1.130  -0.990  -1.034  -1.047
196   L         0.237   0.324   0.236   0.123   0.255   0.124   0.024   0.171  -0.023
197   E        -0.045  -0.100  -0.351   0.052  -0.024  -0.394  -0.078  -0.165  -0.522
198   E        -0.821  -0.735  -0.839  -0.716  -0.597  -0.771  -0.888  -0.788  -0.867
199   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
200   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
201   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
202   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
203   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
204   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
205   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
206   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
207   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
208   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
209   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
210   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
211   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
212   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
213   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
214   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
215   I         0.539   0.416   0.281   0.600   0.436   0.208   0.530   0.329   0.061
216   D        -0.313  -0.181  -0.377  -0.245  -0.047  -0.367  -0.483  -0.291  -0.562
217   S         0.075   0.160   0.195  -0.215  -0.049  -0.017  -0.280  -0.127  -0.102
218   D        -0.540  -0.522  -0.447  -0.669  -0.642  -0.543  -0.787  -0.763  -0.658
219   S         1.151   1.171   1.219   1.047   1.077   1.163   1.240   1.265   1.330
220   K        -0.595  -0.768  -0.860  -0.437  -0.688  -0.848  -0.584  -0.793  -0.886
221   D         1.151   1.171   1.219   1.120   1.154   1.230   1.240   1.265   1.330
222   I        -0.997  -1.006  -0.900  -1.146  -1.155  -0.974  -1.091  -1.081  -0.931
223   Y         1.151   1.171   1.219   1.266   1.299   1.366   1.240   1.265   1.330
224   T         1.151   1.171   1.219   1.211   1.239   1.315   1.240   1.265   1.330
225   V         0.075   0.072   0.150  -0.149  -0.168  -0.049  -0.280  -0.297  -0.189
226   S         0.075   0.160   0.195  -0.224  -0.072  -0.026  -0.280  -0.127  -0.102
227   F         1.151   1.171   1.219   1.165   1.196   1.272   1.240   1.265   1.330
228   G         1.151   1.171   1.219   1.092   1.126   1.205   1.240   1.265   1.330
229   I         1.151   1.171   1.219   1.149   1.181   1.257   1.240   1.265   1.330
230   R         1.151   1.171   1.219   1.195   1.222   1.300   1.240   1.265   1.330
231   N         1.151   1.171   1.219   1.188   1.222   1.293   1.240   1.265   1.330
232   F         0.539   0.472   0.290   0.655   0.582   0.337   0.530   0.422   0.078
233   T         0.539   0.416   0.281   0.651   0.478   0.235   0.530   0.329   0.061
234   D        -0.433  -0.475  -0.422  -0.544  -0.579  -0.471  -0.686  -0.723  -0.631
235   I         1.151   1.171   1.219   1.149   1.181   1.257   1.240   1.265   1.330
236   Q         0.075   0.054   0.150   0.033  -0.027   0.124  -0.280  -0.333  -0.189
237   K         0.075   0.085   0.153  -0.167  -0.161  -0.052  -0.280  -0.271  -0.184
238   G        -0.313  -0.426  -0.433  -0.423  -0.618  -0.628  -0.483  -0.642  -0.642
239   L         1.151   1.171   1.219   1.061   1.091   1.175   1.240   1.265   1.330
240   N        -0.313  -0.446  -0.433  -0.292  -0.493  -0.491  -0.483  -0.660  -0.642
241   T        -0.595  -0.704  -0.825  -0.377  -0.541  -0.741  -0.584  -0.721  -0.846
242   A         1.151   1.171   1.219   1.110   1.130   1.221   1.240   1.265   1.330
243   Y         0.539   0.538   0.296   0.745   0.753   0.409   0.530   0.526   0.090
244   R         1.151   1.171   1.219   1.195   1.222   1.300   1.240   1.265   1.330
245   V         1.151   1.171   1.219   1.122   1.152   1.232   1.240   1.265   1.330
246   L         1.151   1.171   1.219   1.061   1.091   1.175   1.240   1.265   1.330
247   K         0.539   0.600   0.311   0.614   0.705   0.292   0.530   0.621   0.118
248   P         1.151   1.171   1.219   1.253   1.275   1.354   1.240   1.265   1.330
249   G         1.151   1.171   1.219   1.092   1.126   1.205   1.240   1.265   1.330
250   G         1.151   1.171   1.219   1.092   1.126   1.205   1.240   1.265   1.330
251   I         0.075   0.054   0.150  -0.149  -0.208  -0.051  -0.280  -0.333  -0.189
252   F         1.151   1.171   1.219   1.165   1.196   1.272   1.240   1.265   1.330
253   Y        -0.821  -0.757  -0.847  -0.834  -0.752  -0.880  -0.888  -0.795  -0.873
254   C         1.151   1.171   1.219   1.393   1.423   1.484   1.240   1.265   1.330
255   L         1.151   1.171   1.219   1.061   1.091   1.175   1.240   1.265   1.330
256   E         1.151   1.171   1.219   1.180   1.214   1.286   1.240   1.265   1.330
257   F         1.151   1.171   1.219   1.165   1.196   1.272   1.240   1.265   1.330
258   S         1.151   1.171   1.219   1.047   1.077   1.163   1.240   1.265   1.330
259   K         0.237   0.324   0.236   0.207   0.350   0.196   0.024   0.171  -0.023
260   I        -0.433  -0.472  -0.419  -0.610  -0.647  -0.564  -0.686  -0.701  -0.622
261   E        -0.433  -0.434  -0.407  -0.560  -0.525  -0.475  -0.686  -0.655  -0.609
262   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
263   N        -0.045  -0.229  -0.374   0.150  -0.089  -0.306  -0.078  -0.337  -0.554
264   P        -0.045  -0.122  -0.354   0.165   0.049  -0.331  -0.078  -0.184  -0.525
265   L        -0.821  -0.806  -0.841  -0.896  -0.869  -0.905  -0.888  -0.860  -0.869
266   M        -0.821  -0.796  -0.853  -0.850  -0.813  -0.886  -0.888  -0.844  -0.879
267   D        -0.313  -0.396  -0.421  -0.369  -0.497  -0.547  -0.483  -0.594  -0.626
268   F        -1.667  -1.682  -1.536  -1.533  -1.539  -1.332  -1.395  -1.381  -1.197
269   A        -0.821  -0.894  -0.875  -0.896  -1.027  -0.995  -0.888  -0.962  -0.906
270   Y         1.151   1.171   1.219   1.266   1.299   1.366   1.240   1.265   1.330
271   Q        -0.595  -0.768  -0.860  -0.313  -0.573  -0.755  -0.584  -0.793  -0.886
272   Q        -0.313  -0.170  -0.368  -0.231  -0.018  -0.331  -0.483  -0.279  -0.547
273   W         0.024   0.050   0.150   0.018   0.059   0.206  -0.382  -0.341  -0.190
274   A         0.075   0.160   0.195  -0.246  -0.099  -0.046  -0.280  -0.127  -0.102
275   -         1.151   1.171   1.219   1.166   1.198   1.273   1.240   1.265   1.330
276   K        -0.891  -0.831  -0.865  -1.000  -0.920  -0.910  -0.990  -0.917  -0.897
277   V        -0.891  -0.978  -0.878  -1.065  -1.182  -1.015  -0.990  -1.052  -0.909
278   L         0.237   0.170   0.176   0.076  -0.045  -0.049   0.024  -0.108  -0.139
279   P         1.151   1.171   1.219   1.253   1.275   1.354   1.240   1.265   1.330
280   V        -0.433  -0.384  -0.408  -0.640  -0.543  -0.538  -0.686  -0.595  -0.607
281   M        -0.045  -0.229  -0.374   0.192  -0.074  -0.363  -0.078  -0.337  -0.554
282   G         1.151   1.171   1.219   1.092   1.126   1.205   1.240   1.265   1.330
283   S        -0.433  -0.432  -0.414  -0.521  -0.474  -0.453  -0.686  -0.653  -0.616
284   M        -0.891  -0.784  -0.859  -1.006  -0.871  -0.914  -0.990  -0.875  -0.891
285   I         0.075   0.107   0.156  -0.159  -0.106  -0.040  -0.280  -0.228  -0.178
286   A         1.151   1.171   1.219   1.110   1.130   1.221   1.240   1.265   1.330
287   N         0.075   0.054   0.150  -0.130  -0.194  -0.045  -0.280  -0.333  -0.189
288   D         1.151   1.171   1.219   1.120   1.154   1.230   1.240   1.265   1.330
289   Y        -0.433  -0.432  -0.414  -0.490  -0.476  -0.461  -0.686  -0.653  -0.616
290   D        -0.595  -0.557  -0.791  -0.451  -0.395  -0.732  -0.584  -0.537  -0.807
291   S         1.151   1.171   1.219   1.047   1.077   1.163   1.240   1.265   1.330
292   Y         1.151   1.171   1.219   1.266   1.299   1.366   1.240   1.265   1.330
293   Q         0.237   0.241   0.196   0.296   0.299   0.183   0.024   0.023  -0.098
294   Y         1.151   1.171   1.219   1.266   1.299   1.366   1.240   1.265   1.330
295   L         1.151   1.171   1.219   1.061   1.091   1.175   1.240   1.265   1.330
296   V         1.151   1.171   1.219   1.122   1.152   1.232   1.240   1.265   1.330
297   E         1.151   1.171   1.219   1.180   1.214   1.286   1.240   1.265   1.330
298   S         1.151   1.171   1.219   1.047   1.077   1.163   1.240   1.265   1.330
299   I         1.151   1.171   1.219   1.149   1.181   1.257   1.240   1.265   1.330
300   E        -0.313  -0.252  -0.374  -0.307  -0.201  -0.412  -0.483  -0.382  -0.557
301   R         0.539   0.629   0.308   0.651   0.765   0.308   0.530   0.663   0.111
302   F         1.151   1.171   1.219   1.165   1.196   1.272   1.240   1.265   1.330
303   P         1.151   1.171   1.219   1.253   1.275   1.354   1.240   1.265   1.330
304   D        -0.997  -0.971  -0.888  -1.174  -1.133  -0.998  -1.091  -1.047  -0.919
305   Q         0.539   0.472   0.290   0.728   0.641   0.336   0.530   0.422   0.078
306   E         0.539   0.472   0.290   0.635   0.558   0.264   0.530   0.422   0.078
307   T        -1.279  -1.270  -1.226  -1.165  -1.161  -1.084  -1.192  -1.165  -1.070
308   F         1.151   1.171   1.219   1.165   1.196   1.272   1.240   1.265   1.330
309   K        -0.540  -0.579  -0.471  -0.697  -0.776  -0.610  -0.787  -0.838  -0.691
310   S        -1.279  -1.283  -1.234  -1.354  -1.353  -1.254  -1.192  -1.184  -1.078
311   M         1.151   1.171   1.219   1.290   1.324   1.389   1.240   1.265   1.330
312   I         1.151   1.171   1.219   1.149   1.181   1.257   1.240   1.265   1.330
313   E        -0.045  -0.172  -0.364   0.114  -0.062  -0.361  -0.078  -0.259  -0.540
314   K         0.075   0.054   0.150  -0.147  -0.198  -0.050  -0.280  -0.333  -0.189
315   A         1.151   1.171   1.219   1.110   1.130   1.221   1.240   1.265   1.330
316   G         1.151   1.171   1.219   1.092   1.126   1.205   1.240   1.265   1.330
317   F         1.151   1.171   1.219   1.165   1.196   1.272   1.240   1.265   1.330
318   K        -1.385  -1.355  -1.248  -1.305  -1.269  -1.098  -1.294  -1.246  -1.090
319   -        -0.564  -0.510  -0.451  -0.852  -0.772  -0.660  -0.836  -0.762  -0.665
320   -        -0.564  -0.565  -0.459  -0.773  -0.790  -0.619  -0.836  -0.823  -0.674
321   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
322   S        -0.609  -0.601  -0.471  -0.908  -0.890  -0.684  -0.888  -0.868  -0.691
323   A        -1.949  -1.925  -1.776  -1.767  -1.729  -1.514  -1.496  -1.456  -1.272
324   G         1.151   1.171   1.219   1.092   1.126   1.205   1.240   1.265   1.330
325   Y         1.151   1.171   1.219   1.266   1.299   1.366   1.240   1.265   1.330
326   E         0.539   0.538   0.296   0.635   0.645   0.275   0.530   0.526   0.090
327   S        -0.821  -0.907  -0.861  -0.836  -0.946  -0.905  -0.888  -0.961  -0.889
328   L         1.151   1.171   1.219   1.061   1.091   1.175   1.240   1.265   1.330
329   T         0.237   0.246   0.185   0.189   0.196   0.037   0.024   0.033  -0.120
330   F         0.539   0.416   0.281   0.611   0.446   0.211   0.530   0.329   0.061
331   G         1.151   1.171   1.219   1.092   1.126   1.205   1.240   1.265   1.330
332   I         0.075   0.108   0.159  -0.159  -0.103  -0.034  -0.280  -0.226  -0.171
333   C        -0.433  -0.336  -0.399  -0.479  -0.356  -0.434  -0.686  -0.540  -0.594
334   A         0.237   0.324   0.236   0.090   0.224   0.060   0.024   0.171  -0.023
335   I         0.539   0.538   0.296   0.600   0.606   0.237   0.530   0.526   0.090
336   H         1.151   1.171   1.219   1.322   1.350   1.418   1.240   1.265   1.330
337   W        -0.891  -0.977  -0.884  -0.782  -0.900  -0.777  -0.990  -1.051  -0.915
338   G         1.151   1.171   1.219   1.092   1.126   1.205   1.240   1.265   1.330
339   I        -0.433  -0.499  -0.426  -0.573  -0.639  -0.512  -0.686  -0.745  -0.636
340   K         1.151   1.171   1.219   1.153   1.193   1.261   1.240   1.265   1.330
341   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
342   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
343   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
344   V        -1.279  -1.213  -1.215  -1.345  -1.249  -1.228  -1.192  -1.113  -1.060
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P49017
Output conservation file - output/P49017
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
