1     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
2     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    -        -0.108  -0.108  -0.091  -0.140  -0.135  -0.111  -0.299  -0.298  -0.270
18    -        -0.108  -0.108  -0.091  -0.237  -0.244  -0.207  -0.299  -0.298  -0.270
19    -        -0.108  -0.108  -0.091  -0.069  -0.070  -0.040  -0.299  -0.298  -0.270
20    -        -0.108  -0.108  -0.091  -0.269  -0.261  -0.240  -0.299  -0.298  -0.270
21    M         0.041   0.034  -0.005   0.113   0.112   0.054  -0.061  -0.072  -0.134
22    Q         0.041   0.034  -0.005  -0.028  -0.042  -0.118  -0.061  -0.072  -0.134
23    C        -1.179  -1.178  -1.162  -1.117  -1.107  -1.087  -1.013  -1.011  -0.982
24    N         0.041   0.025  -0.001  -0.086  -0.118  -0.178  -0.061  -0.086  -0.128
25    T        -1.179  -1.178  -1.162  -1.091  -1.077  -1.061  -1.013  -1.011  -0.982
26    S         1.722   1.724   1.741   1.430   1.423   1.460   1.843   1.844   1.866
27    -        -0.108  -0.108  -0.091  -0.335  -0.348  -0.306  -0.299  -0.298  -0.270
28    -        -0.108  -0.108  -0.091  -0.007  -0.013   0.022  -0.299  -0.298  -0.270
29    -        -0.108  -0.108  -0.091  -0.085  -0.102  -0.055  -0.299  -0.298  -0.270
30    I        -1.179  -1.178  -1.162  -0.897  -0.887  -0.867  -1.013  -1.011  -0.982
31    E         0.041   0.034  -0.005   0.026   0.018  -0.056  -0.061  -0.072  -0.134
32    D        -1.179  -1.178  -1.162  -1.117  -1.125  -1.087  -1.013  -1.011  -0.982
33    G        -1.179  -1.178  -1.162  -1.190  -1.191  -1.160  -1.013  -1.011  -0.982
34    L         1.722   1.724   1.741   1.678   1.685   1.708   1.843   1.844   1.866
35    D         0.041   0.025  -0.001   0.026   0.003  -0.049  -0.061  -0.086  -0.128
36    G        -1.179  -1.178  -1.162  -0.980  -0.992  -0.951  -1.013  -1.011  -0.982
37    G         1.722   1.724   1.741   1.876   1.876   1.905   1.843   1.844   1.866
38    D         0.041   0.068   0.006   0.026   0.075  -0.035  -0.061  -0.019  -0.115
39    I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
40    T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
41    F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
42    P        -0.108  -0.108  -0.091  -0.050  -0.052  -0.020  -0.299  -0.298  -0.270
43    S        -0.108  -0.108  -0.091  -0.602  -0.611  -0.572  -0.299  -0.298  -0.270
44    Y        -0.108  -0.108  -0.091   0.073   0.072   0.103  -0.299  -0.298  -0.270
45    S        -0.108  -0.108  -0.091  -0.345  -0.351  -0.316  -0.299  -0.298  -0.270
46    P        -0.108  -0.108  -0.091  -0.186  -0.180  -0.156  -0.299  -0.298  -0.270
47    E        -0.108  -0.108  -0.091  -0.122  -0.116  -0.092  -0.299  -0.298  -0.270
48    A        -0.108  -0.108  -0.091  -0.345  -0.351  -0.316  -0.299  -0.298  -0.270
49    E        -1.179  -1.178  -1.162  -1.442  -1.444  -1.413  -1.013  -1.011  -0.982
50    A        -1.179  -1.178  -1.162  -0.863  -0.865  -0.834  -1.013  -1.011  -0.982
51    Q         0.041   0.068   0.006  -0.110  -0.073  -0.164  -0.061  -0.019  -0.115
52    N         0.041   0.068   0.006   0.136   0.179   0.087  -0.061  -0.019  -0.115
53    R        -0.108  -0.108  -0.091  -0.086  -0.092  -0.057  -0.299  -0.298  -0.270
54    F         1.722   1.724   1.741   1.874   1.889   1.904   1.843   1.844   1.866
55    L         1.722   1.724   1.741   1.678   1.685   1.708   1.843   1.844   1.866
56    P         0.041   0.025  -0.001   0.213   0.194   0.154  -0.061  -0.086  -0.128
57    R        -1.179  -1.178  -1.162  -1.111  -1.110  -1.082  -1.013  -1.011  -0.982
58    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
59    S         0.041   0.068   0.006  -0.198  -0.169  -0.244  -0.061  -0.019  -0.115
60    E         0.041   0.068   0.006  -0.001   0.047  -0.058  -0.061  -0.019  -0.115
61    F        -0.108  -0.108  -0.091  -0.116  -0.107  -0.086  -0.299  -0.298  -0.270
62    P        -1.179  -1.178  -1.162  -1.127  -1.116  -1.097  -1.013  -1.011  -0.982
63    S         1.722   1.724   1.741   1.430   1.423   1.460   1.843   1.844   1.866
64    V         1.722   1.724   1.741   1.769   1.776   1.799   1.843   1.844   1.866
65    R         1.722   1.724   1.741   1.661   1.659   1.691   1.843   1.844   1.866
66    Q         0.041   0.034  -0.005  -0.083  -0.096  -0.171  -0.061  -0.072  -0.134
67    L         1.722   1.724   1.741   1.678   1.685   1.708   1.843   1.844   1.866
68    V         1.722   1.724   1.741   1.769   1.776   1.799   1.843   1.844   1.866
69    I         1.722   1.724   1.741   1.868   1.866   1.897   1.843   1.844   1.866
70    S         0.041   0.068   0.006  -0.230  -0.198  -0.280  -0.061  -0.019  -0.115
71    K         0.041   0.068   0.006   0.083   0.129   0.004  -0.061  -0.019  -0.115
72    Q         1.722   1.724   1.741   1.560   1.553   1.589   1.843   1.844   1.866
73    K        -1.179  -1.178  -1.162  -1.030  -1.023  -1.000  -1.013  -1.011  -0.982
74    S        -1.179  -1.178  -1.162  -1.163  -1.168  -1.134  -1.013  -1.011  -0.982
75    R         1.722   1.724   1.741   1.661   1.659   1.691   1.843   1.844   1.866
76    R        -1.179  -1.178  -1.162  -1.010  -1.012  -0.980  -1.013  -1.011  -0.982
77    R        -1.179  -1.178  -1.162  -1.076  -1.065  -1.046  -1.013  -1.011  -0.982
78    R         0.041   0.025  -0.001   0.014  -0.011  -0.050  -0.061  -0.086  -0.128
79    E        -1.179  -1.178  -1.162  -1.148  -1.135  -1.118  -1.013  -1.011  -0.982
80    E        -1.179  -1.178  -1.162  -1.045  -1.044  -1.016  -1.013  -1.011  -0.982
81    N         1.722   1.724   1.741   1.736   1.743   1.766   1.843   1.844   1.866
82    V        -1.179  -1.178  -1.162  -1.232  -1.234  -1.203  -1.013  -1.011  -0.982
83    F         0.041   0.025  -0.001   0.177   0.155   0.096  -0.061  -0.086  -0.128
84    V         0.041   0.025  -0.001   0.195   0.180   0.138  -0.061  -0.086  -0.128
85    G         0.041   0.068   0.006   0.154   0.201   0.089  -0.061  -0.019  -0.115
86    K         0.041   0.025  -0.001   0.184   0.151   0.102  -0.061  -0.086  -0.128
87    M         1.722   1.724   1.741   1.980   1.988   2.010   1.843   1.844   1.866
88    E         1.722   1.724   1.741   1.678   1.683   1.708   1.843   1.844   1.866
89    D         1.722   1.724   1.741   1.736   1.740   1.766   1.843   1.844   1.866
90    V        -1.179  -1.178  -1.162  -1.184  -1.183  -1.155  -1.013  -1.011  -0.982
91    L         1.722   1.724   1.741   1.678   1.685   1.708   1.843   1.844   1.866
92    V         1.722   1.724   1.741   1.769   1.776   1.799   1.843   1.844   1.866
93    K         0.041   0.025  -0.001   0.184   0.151   0.102  -0.061  -0.086  -0.128
94    W         1.722   1.724   1.741   2.012   2.013   2.042   1.843   1.844   1.866
95    R         0.041   0.025  -0.001   0.068   0.040   0.010  -0.061  -0.086  -0.128
96    P         0.041   0.025  -0.001   0.079   0.054   0.001  -0.061  -0.086  -0.128
97    P         1.722   1.724   1.741   1.802   1.809   1.832   1.843   1.844   1.866
98    A         0.041   0.068   0.006   0.087   0.133   0.024  -0.061  -0.019  -0.115
99    S         1.722   1.724   1.741   1.430   1.423   1.460   1.843   1.844   1.866
100   S         1.722   1.724   1.741   1.430   1.423   1.460   1.843   1.844   1.866
101   H         0.041   0.068   0.006   0.254   0.299   0.190  -0.061  -0.019  -0.115
102   R         0.041   0.025  -0.001  -0.043  -0.071  -0.116  -0.061  -0.086  -0.128
103   G         1.722   1.724   1.741   1.876   1.876   1.905   1.843   1.844   1.866
104   A         0.041   0.034  -0.005   0.091   0.089   0.017  -0.061  -0.072  -0.134
105   I         0.041   0.034  -0.005   0.143   0.136   0.073  -0.061  -0.072  -0.134
106   E        -1.179  -1.178  -1.162  -1.086  -1.092  -1.056  -1.013  -1.011  -0.982
107   A         0.041   0.025  -0.001   0.128   0.103   0.057  -0.061  -0.086  -0.128
108   I         1.722   1.724   1.741   1.868   1.866   1.897   1.843   1.844   1.866
109   N         0.041   0.034  -0.005  -0.001  -0.007  -0.077  -0.061  -0.072  -0.134
110   G         1.722   1.724   1.741   1.876   1.876   1.905   1.843   1.844   1.866
111   T         0.041   0.068   0.006   0.143   0.192   0.094  -0.061  -0.019  -0.115
112   H         1.722   1.724   1.741   1.956   1.955   1.986   1.843   1.844   1.866
113   P         1.722   1.724   1.741   1.802   1.809   1.832   1.843   1.844   1.866
114   Y         1.722   1.724   1.741   1.940   1.939   1.970   1.843   1.844   1.866
115   Q         1.722   1.724   1.741   1.560   1.553   1.589   1.843   1.844   1.866
116   L        -0.108  -0.108  -0.091  -0.176  -0.161  -0.146  -0.299  -0.298  -0.270
117   S        -0.108  -0.108  -0.091  -0.361  -0.351  -0.331  -0.299  -0.298  -0.270
118   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
119   A         1.722   1.724   1.741   1.782   1.794   1.812   1.843   1.844   1.866
120   Q        -0.108  -0.108  -0.091  -0.384  -0.400  -0.355  -0.299  -0.298  -0.270
121   F        -0.108  -0.108  -0.091  -0.020  -0.009   0.009  -0.299  -0.298  -0.270
122   N        -0.108  -0.108  -0.091  -0.013  -0.009   0.016  -0.299  -0.298  -0.270
123   S        -0.108  -0.108  -0.091  -0.361  -0.351  -0.331  -0.299  -0.298  -0.270
124   R        -0.108  -0.108  -0.091  -0.244  -0.247  -0.215  -0.299  -0.298  -0.270
125   R        -0.108  -0.108  -0.091  -0.260  -0.255  -0.230  -0.299  -0.298  -0.270
126   S        -0.108  -0.108  -0.091  -0.153  -0.153  -0.124  -0.299  -0.298  -0.270
127   D         1.722   1.724   1.741   1.730   1.730   1.760   1.843   1.844   1.866
128   P         1.722   1.724   1.741   1.772   1.773   1.802   1.843   1.844   1.866
129   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
130   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
131   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
132   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
133   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
134   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
135   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
136   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
137   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
138   F        -1.179  -1.178  -1.162  -1.101  -1.099  -1.072  -1.013  -1.011  -0.982
139   G         0.041   0.025  -0.001   0.154   0.126   0.075  -0.061  -0.086  -0.128
140   S        -1.179  -1.178  -1.162  -1.243  -1.240  -1.213  -1.013  -1.011  -0.982
141   T        -1.179  -1.178  -1.162  -0.970  -0.963  -0.941  -1.013  -1.011  -0.982
142   K        -1.179  -1.178  -1.162  -1.163  -1.165  -1.134  -1.013  -1.011  -0.982
143   R        -1.179  -1.178  -1.162  -1.096  -1.088  -1.066  -1.013  -1.011  -0.982
144   D        -1.179  -1.178  -1.162  -1.335  -1.344  -1.306  -1.013  -1.011  -0.982
145   E         0.041   0.034  -0.005  -0.138  -0.155  -0.214  -0.061  -0.072  -0.134
146   S        -1.179  -1.178  -1.162  -1.122  -1.123  -1.092  -1.013  -1.011  -0.982
147   V        -1.179  -1.178  -1.162  -1.086  -1.073  -1.056  -1.013  -1.011  -0.982
148   R        -1.179  -1.178  -1.162  -1.190  -1.209  -1.160  -1.013  -1.011  -0.982
149   S        -1.179  -1.178  -1.162  -1.397  -1.405  -1.367  -1.013  -1.011  -0.982
150   I         0.041   0.068   0.006   0.283   0.322   0.234  -0.061  -0.019  -0.115
151   V        -1.179  -1.178  -1.162  -1.020  -1.019  -0.990  -1.013  -1.011  -0.982
152   E         0.041   0.034  -0.005   0.026   0.018  -0.056  -0.061  -0.072  -0.134
153   S         0.041   0.025  -0.001  -0.198  -0.230  -0.255  -0.061  -0.086  -0.128
154   F         1.722   1.724   1.741   1.900   1.906   1.930   1.843   1.844   1.866
155   T         0.041   0.025  -0.001  -0.079  -0.104  -0.170  -0.061  -0.086  -0.128
156   D        -1.179  -1.178  -1.162  -0.956  -0.952  -0.926  -1.013  -1.011  -0.982
157   W         0.041   0.025  -0.001   0.272   0.240   0.187  -0.061  -0.086  -0.128
158   W         0.041   0.025  -0.001   0.411   0.388   0.346  -0.061  -0.086  -0.128
159   K         0.041   0.025  -0.001   0.139   0.103   0.051  -0.061  -0.086  -0.128
160   R         0.041   0.068   0.006  -0.043  -0.002  -0.103  -0.061  -0.019  -0.115
161   N         1.722   1.724   1.741   1.736   1.743   1.766   1.843   1.844   1.866
162   S         0.041   0.068   0.006  -0.198  -0.169  -0.244  -0.061  -0.019  -0.115
163   K        -1.179  -1.178  -1.162  -0.951  -0.948  -0.921  -1.013  -1.011  -0.982
164   M        -1.179  -1.178  -1.162  -0.863  -0.856  -0.834  -1.013  -1.011  -0.982
165   F        -0.108  -0.108  -0.091  -0.072  -0.054  -0.042  -0.299  -0.298  -0.270
166   F        -0.108  -0.108  -0.091  -0.161  -0.138  -0.131  -0.299  -0.298  -0.270
167   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
168   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
169   -        -0.108  -0.108  -0.091  -0.228  -0.227  -0.199  -0.299  -0.298  -0.270
170   -        -0.108  -0.108  -0.091  -0.253  -0.253  -0.223  -0.299  -0.298  -0.270
171   -         1.722   1.724   1.741   1.569   1.558   1.599   1.843   1.844   1.866
172   R        -1.179  -1.178  -1.162  -1.292  -1.291  -1.262  -1.013  -1.011  -0.982
173   D         0.041   0.068   0.006   0.128   0.172   0.079  -0.061  -0.019  -0.115
174   E         1.722   1.724   1.741   1.678   1.683   1.708   1.843   1.844   1.866
175   E         1.722   1.724   1.741   1.678   1.683   1.708   1.843   1.844   1.866
176   E         1.722   1.724   1.741   1.678   1.683   1.708   1.843   1.844   1.866
177   -        -0.108  -0.108  -0.091  -0.148  -0.127  -0.119  -0.299  -0.298  -0.270
178   -         1.722   1.724   1.741   1.603   1.605   1.633   1.843   1.844   1.866
179   -        -0.108  -0.108  -0.091  -0.109  -0.110  -0.079  -0.299  -0.298  -0.270
180   -        -0.108  -0.108  -0.091  -0.188  -0.194  -0.158  -0.299  -0.298  -0.270
181   -        -0.108  -0.108  -0.091  -0.462  -0.463  -0.432  -0.299  -0.298  -0.270
182   -         1.722   1.724   1.741   1.715   1.722   1.744   1.843   1.844   1.866
183   -         1.722   1.724   1.741   1.603   1.605   1.633   1.843   1.844   1.866
184   -        -0.108  -0.108  -0.091  -0.212  -0.227  -0.183  -0.299  -0.298  -0.270
185   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
186   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
187   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
188   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
189   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
190   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
191   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
192   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
193   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
194   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
195   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
196   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
197   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
198   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
199   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
200   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
201   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
202   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
203   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
204   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
205   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
206   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
207   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
208   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
209   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
210   G         0.041   0.034  -0.005   0.117   0.111   0.048  -0.061  -0.072  -0.134
211   V         0.041   0.034  -0.005   0.075   0.077  -0.001  -0.061  -0.072  -0.134
212   R         0.041   0.034  -0.005  -0.036  -0.046  -0.117  -0.061  -0.072  -0.134
213   T         0.041   0.025  -0.001   0.121   0.104   0.057  -0.061  -0.086  -0.128
214   E        -1.179  -1.178  -1.162  -1.065  -1.057  -1.036  -1.013  -1.011  -0.982
215   H        -0.108  -0.108  -0.091  -0.206  -0.208  -0.176  -0.299  -0.298  -0.270
216   S        -0.108  -0.108  -0.091  -0.361  -0.351  -0.331  -0.299  -0.298  -0.270
217   A        -0.108  -0.108  -0.091  -0.229  -0.208  -0.199  -0.299  -0.298  -0.270
218   S        -0.108  -0.108  -0.091  -0.353  -0.351  -0.323  -0.299  -0.298  -0.270
219   Q        -0.108  -0.108  -0.091  -0.290  -0.295  -0.261  -0.299  -0.298  -0.270
220   D         0.041   0.034  -0.005   0.053   0.047  -0.025  -0.061  -0.072  -0.134
221   D        -1.179  -1.178  -1.162  -0.965  -0.954  -0.936  -1.013  -1.011  -0.982
222   Q        -1.179  -1.178  -1.162  -1.050  -1.055  -1.021  -1.013  -1.011  -0.982
223   E         0.041   0.025  -0.001  -0.001  -0.023  -0.071  -0.061  -0.086  -0.128
224   L         0.041   0.025  -0.001   0.083   0.064   0.025  -0.061  -0.086  -0.128
225   Q         0.041   0.034  -0.005   0.034   0.016  -0.059  -0.061  -0.072  -0.134
226   L        -1.179  -1.178  -1.162  -1.076  -1.065  -1.046  -1.013  -1.011  -0.982
227   F        -1.179  -1.178  -1.162  -1.025  -1.007  -0.995  -1.013  -1.011  -0.982
228   E        -1.179  -1.178  -1.162  -1.045  -1.039  -1.016  -1.013  -1.011  -0.982
229   E         0.041   0.068   0.006  -0.142  -0.093  -0.216  -0.061  -0.019  -0.115
230   D        -1.179  -1.178  -1.162  -1.254  -1.254  -1.224  -1.013  -1.011  -0.982
231   L        -1.179  -1.178  -1.162  -1.086  -1.077  -1.056  -1.013  -1.011  -0.982
232   F         0.041   0.034  -0.005   0.128   0.122   0.061  -0.061  -0.072  -0.134
233   S        -1.179  -1.178  -1.162  -1.319  -1.313  -1.289  -1.013  -1.011  -0.982
234   F        -1.179  -1.178  -1.162  -0.916  -0.908  -0.887  -1.013  -1.011  -0.982
235   H         0.041   0.034  -0.005   0.087   0.072   0.026  -0.061  -0.072  -0.134
236   L         0.041   0.025  -0.001  -0.142  -0.172  -0.231  -0.061  -0.086  -0.128
237   S        -1.179  -1.178  -1.162  -1.324  -1.323  -1.295  -1.013  -1.011  -0.982
238   P         0.041   0.034  -0.005   0.202   0.191   0.124  -0.061  -0.072  -0.134
239   N        -1.179  -1.178  -1.162  -1.200  -1.192  -1.171  -1.013  -1.011  -0.982
240   D         1.722   1.724   1.741   1.736   1.740   1.766   1.843   1.844   1.866
241   M        -1.179  -1.178  -1.162  -1.015  -1.001  -0.985  -1.013  -1.011  -0.982
242   S         0.041   0.025  -0.001  -0.130  -0.160  -0.178  -0.061  -0.086  -0.128
243   T         0.041   0.034  -0.005   0.056   0.055  -0.021  -0.061  -0.072  -0.134
244   R        -1.179  -1.178  -1.162  -1.292  -1.290  -1.262  -1.013  -1.011  -0.982
245   N        -1.179  -1.178  -1.162  -1.005  -0.997  -0.975  -1.013  -1.011  -0.982
246   S        -1.179  -1.178  -1.162  -1.195  -1.198  -1.165  -1.013  -1.011  -0.982
247   E         0.041   0.034  -0.005  -0.259  -0.277  -0.330  -0.061  -0.072  -0.134
248   H        -1.179  -1.178  -1.162  -0.990  -0.977  -0.961  -1.013  -1.011  -0.982
249   Q        -0.108  -0.108  -0.091  -0.198  -0.216  -0.169  -0.299  -0.298  -0.270
250   V         1.722   1.724   1.741   1.720   1.719   1.750   1.843   1.844   1.866
251   Q        -0.108  -0.108  -0.091  -0.497  -0.509  -0.467  -0.299  -0.298  -0.270
252   T        -0.108  -0.108  -0.091  -0.353  -0.351  -0.323  -0.299  -0.298  -0.270
253   P        -0.108  -0.108  -0.091  -0.275  -0.287  -0.245  -0.299  -0.298  -0.270
254   V        -0.108  -0.108  -0.091  -0.116  -0.122  -0.086  -0.299  -0.298  -0.270
255   L         0.041   0.034  -0.005   0.034   0.034  -0.049  -0.061  -0.072  -0.134
256   F         0.041   0.025  -0.001   0.232   0.208   0.159  -0.061  -0.086  -0.128
257   P        -1.179  -1.178  -1.162  -0.980  -0.967  -0.951  -1.013  -1.011  -0.982
258   Y         0.041   0.034  -0.005   0.206   0.193   0.139  -0.061  -0.072  -0.134
259   E        -1.179  -1.178  -1.162  -1.158  -1.150  -1.129  -1.013  -1.011  -0.982
260   A         0.041   0.034  -0.005   0.143   0.136   0.067  -0.061  -0.072  -0.134
261   P        -1.179  -1.178  -1.162  -0.956  -0.950  -0.926  -1.013  -1.011  -0.982
262   T         0.041   0.068   0.006   0.075   0.131   0.019  -0.061  -0.019  -0.115
263   R        -1.179  -1.178  -1.162  -1.065  -1.069  -1.036  -1.013  -1.011  -0.982
264   T         0.041   0.025  -0.001   0.143   0.128   0.083  -0.061  -0.086  -0.128
265   K        -1.179  -1.178  -1.162  -0.980  -0.974  -0.951  -1.013  -1.011  -0.982
266   Q         0.041   0.034  -0.005   0.034   0.022  -0.059  -0.061  -0.072  -0.134
267   N         0.041   0.034  -0.005   0.113   0.102   0.033  -0.061  -0.072  -0.134
268   P        -0.108  -0.108  -0.091  -0.146  -0.138  -0.116  -0.299  -0.298  -0.270
269   A        -0.108  -0.108  -0.091  -0.183  -0.176  -0.154  -0.299  -0.298  -0.270
270   E        -0.108  -0.108  -0.091  -0.298  -0.303  -0.268  -0.299  -0.298  -0.270
271   R         1.722   1.724   1.741   1.647   1.643   1.676   1.843   1.844   1.866
272   K        -0.108  -0.108  -0.091  -0.146  -0.145  -0.116  -0.299  -0.298  -0.270
273   V        -0.108  -0.108  -0.091  -0.283  -0.287  -0.253  -0.299  -0.298  -0.270
274   I        -0.108  -0.108  -0.091  -0.214  -0.223  -0.184  -0.299  -0.298  -0.270
275   E        -0.108  -0.108  -0.091  -0.384  -0.400  -0.355  -0.299  -0.298  -0.270
276   I        -0.108  -0.108  -0.091  -0.176  -0.161  -0.146  -0.299  -0.298  -0.270
277   G        -0.108  -0.108  -0.091  -0.198  -0.216  -0.169  -0.299  -0.298  -0.270
278   D        -0.108  -0.108  -0.091  -0.306  -0.319  -0.276  -0.299  -0.298  -0.270
279   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
280   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
281   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
282   -         1.722   1.724   1.741   1.726   1.722   1.756   1.843   1.844   1.866
283   -         1.722   1.724   1.741   1.682   1.687   1.711   1.843   1.844   1.866
284   G         0.041   0.025  -0.001   0.180   0.153   0.104  -0.061  -0.086  -0.128
285   E        -1.179  -1.178  -1.162  -1.091  -1.088  -1.061  -1.013  -1.011  -0.982
286   E        -1.179  -1.178  -1.162  -0.960  -0.946  -0.931  -1.013  -1.011  -0.982
287   L        -1.179  -1.178  -1.162  -1.086  -1.072  -1.056  -1.013  -1.011  -0.982
288   S        -1.179  -1.178  -1.162  -1.313  -1.319  -1.284  -1.013  -1.011  -0.982
289   I         0.041   0.025  -0.001   0.173   0.145   0.097  -0.061  -0.086  -0.128
290   Y         0.041   0.025  -0.001   0.106   0.066   0.009  -0.061  -0.086  -0.128
291   R        -1.179  -1.178  -1.162  -1.292  -1.297  -1.262  -1.013  -1.011  -0.982
292   D        -1.179  -1.178  -1.162  -1.005  -0.996  -0.975  -1.013  -1.011  -0.982
293   V         0.041   0.025  -0.001   0.087   0.070   0.015  -0.061  -0.086  -0.128
294   Y         1.722   1.724   1.741   1.940   1.939   1.970   1.843   1.844   1.866
295   S        -1.179  -1.178  -1.162  -1.143  -1.143  -1.113  -1.013  -1.011  -0.982
296   N        -1.179  -1.178  -1.162  -0.931  -0.926  -0.901  -1.013  -1.011  -0.982
297   P         1.722   1.724   1.741   1.802   1.809   1.832   1.843   1.844   1.866
298   I         0.041   0.068   0.006   0.188   0.231   0.128  -0.061  -0.019  -0.115
299   P         1.722   1.724   1.741   1.802   1.809   1.832   1.843   1.844   1.866
300   V         0.041   0.025  -0.001   0.003  -0.025  -0.081  -0.061  -0.086  -0.128
301   S        -1.179  -1.178  -1.162  -1.111  -1.117  -1.082  -1.013  -1.011  -0.982
302   Y         1.722   1.724   1.741   1.940   1.939   1.970   1.843   1.844   1.866
303   L         1.722   1.724   1.741   1.678   1.685   1.708   1.843   1.844   1.866
304   D         0.041   0.034  -0.005   0.113   0.108   0.033  -0.061  -0.072  -0.134
305   T        -1.179  -1.178  -1.162  -0.936  -0.923  -0.906  -1.013  -1.011  -0.982
306   L         0.041   0.034  -0.005  -0.259  -0.276  -0.330  -0.061  -0.072  -0.134
307   N         0.041   0.025  -0.001  -0.028  -0.056  -0.111  -0.061  -0.086  -0.128
308   L        -1.179  -1.178  -1.162  -1.243  -1.242  -1.213  -1.013  -1.011  -0.982
309   N        -1.179  -1.178  -1.162  -1.206  -1.207  -1.176  -1.013  -1.011  -0.982
310   H        -1.179  -1.178  -1.162  -1.025  -1.029  -0.995  -1.013  -1.011  -0.982
311   S        -1.179  -1.178  -1.162  -1.335  -1.338  -1.306  -1.013  -1.011  -0.982
312   M        -1.179  -1.178  -1.162  -0.825  -0.820  -0.796  -1.013  -1.011  -0.982
313   S         0.041   0.025  -0.001  -0.230  -0.261  -0.292  -0.061  -0.086  -0.128
314   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
315   R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
316   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
317   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
318   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
319   Q         0.041   0.025  -0.001  -0.110  -0.140  -0.176  -0.061  -0.086  -0.128
320   Q         0.041   0.025  -0.001  -0.094  -0.124  -0.158  -0.061  -0.086  -0.128
321   Q        -1.179  -1.178  -1.162  -1.238  -1.229  -1.208  -1.013  -1.011  -0.982
322   Q        -1.179  -1.178  -1.162  -1.402  -1.400  -1.373  -1.013  -1.011  -0.982
323   Q         0.041   0.025  -0.001  -0.255  -0.297  -0.341  -0.061  -0.086  -0.128
324   R         1.722   1.724   1.741   1.661   1.659   1.691   1.843   1.844   1.866
325   Q         1.722   1.724   1.741   1.560   1.553   1.589   1.843   1.844   1.866
326   Q        -1.179  -1.178  -1.162  -1.096  -1.092  -1.066  -1.013  -1.011  -0.982
327   Q        -1.179  -1.178  -1.162  -1.238  -1.230  -1.208  -1.013  -1.011  -0.982
328   Q         0.041   0.068   0.006  -0.005   0.023  -0.046  -0.061  -0.019  -0.115
329   Y        -1.179  -1.178  -1.162  -0.912  -0.907  -0.882  -1.013  -1.011  -0.982
330   V         0.041   0.034  -0.005  -0.214  -0.230  -0.279  -0.061  -0.072  -0.134
331   D         0.041   0.034  -0.005  -0.110  -0.127  -0.182  -0.061  -0.072  -0.134
332   S        -1.179  -1.178  -1.162  -1.286  -1.287  -1.256  -1.013  -1.011  -0.982
333   S        -1.179  -1.178  -1.162  -1.243  -1.247  -1.213  -1.013  -1.011  -0.982
334   S         0.041   0.068   0.006  -0.162  -0.134  -0.204  -0.061  -0.019  -0.115
335   A        -0.108  -0.108  -0.091  -0.146  -0.138  -0.116  -0.299  -0.298  -0.270
336   F        -0.108  -0.108  -0.091  -0.161  -0.138  -0.131  -0.299  -0.298  -0.270
337   Q        -1.179  -1.178  -1.162  -0.931  -0.936  -0.901  -1.013  -1.011  -0.982
338   C         0.041   0.034  -0.005  -0.075  -0.091  -0.120  -0.061  -0.072  -0.134
339   C         1.722   1.724   1.741   2.051   2.053   2.081   1.843   1.844   1.866
340   T         0.041   0.034  -0.005  -0.226  -0.240  -0.293  -0.061  -0.072  -0.134
341   D        -0.108  -0.108  -0.091  -0.306  -0.319  -0.276  -0.299  -0.298  -0.270
342   S        -0.108  -0.108  -0.091  -0.353  -0.351  -0.323  -0.299  -0.298  -0.270
343   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
344   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
345   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
346   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
347   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
348   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
349   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
350   N        -1.179  -1.178  -1.162  -1.324  -1.326  -1.295  -1.013  -1.011  -0.982
351   W         1.722   1.724   1.741   2.012   2.013   2.042   1.843   1.844   1.866
352   A        -1.179  -1.178  -1.162  -1.281  -1.273  -1.251  -1.013  -1.011  -0.982
353   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
354   R        -0.108  -0.108  -0.091  -0.237  -0.231  -0.207  -0.299  -0.298  -0.270
355   I         1.722   1.724   1.741   1.854   1.857   1.884   1.843   1.844   1.866
356   F        -0.108  -0.108  -0.091   0.080   0.095   0.110  -0.299  -0.298  -0.270
357   F        -0.108  -0.108  -0.091  -0.094  -0.076  -0.064  -0.299  -0.298  -0.270
358   C         1.722   1.724   1.741   2.051   2.053   2.081   1.843   1.844   1.866
359   H        -1.179  -1.178  -1.162  -0.897  -0.884  -0.867  -1.013  -1.011  -0.982
360   H         0.041   0.034  -0.005   0.162   0.160   0.098  -0.061  -0.072  -0.134
361   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
362   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
363   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
364   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
365   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
366   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
367   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
368   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
369   D        -0.108  -0.108  -0.091  -0.183  -0.184  -0.154  -0.299  -0.298  -0.270
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P48568
Output conservation file - output/P48568
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
