1     M         1.900   1.907   2.044   2.082   2.097   2.309   2.113   2.124   2.347
2     S         0.461   0.445   0.212   0.578   0.561   0.270   0.480   0.450   0.094
3     G        -1.491  -1.436  -1.389  -1.189  -1.125  -1.033  -1.154  -1.109  -1.007
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -         1.900   1.907   2.044   2.009   2.018   2.236   2.113   2.124   2.347
9     -         0.041  -0.066  -0.007   0.088  -0.087  -0.003  -0.139  -0.300  -0.239
10    -        -0.707  -0.629  -0.594  -0.647  -0.545  -0.499  -0.782  -0.693  -0.639
11    -         0.041   0.006   0.012  -0.298  -0.364  -0.348  -0.139  -0.195  -0.210
12    -         1.900   1.907   2.044   2.030   2.038   2.257   2.113   2.124   2.347
13    -         0.041   0.036   0.033   0.225   0.214   0.184  -0.139  -0.154  -0.179
14    -        -0.164  -0.170  -0.050  -0.264  -0.239  -0.059  -0.460  -0.462  -0.306
15    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
19    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
20    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
21    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
22    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
23    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
24    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
25    P        -0.599  -0.566  -0.541  -0.469  -0.435  -0.373  -0.677  -0.639  -0.585
26    P         1.163   1.139   0.994   1.405   1.375   1.182   1.234   1.194   0.904
27    P         1.900   1.907   2.044   2.045   2.056   2.271   2.113   2.124   2.347
28    P        -1.133  -1.052  -1.042  -1.021  -0.925  -0.901  -1.005  -0.934  -0.871
29    Y         1.098   1.184   0.974   1.258   1.371   1.071   1.129   1.265   0.867
30    E         0.030  -0.040   0.011   0.177   0.068   0.121  -0.185  -0.279  -0.226
31    E        -0.986  -0.876  -0.979  -0.597  -0.443  -0.601  -0.841  -0.722  -0.805
32    Q        -0.986  -1.034  -1.002  -0.722  -0.807  -0.802  -0.841  -0.892  -0.828
33    -        -1.606  -1.571  -1.446  -1.519  -1.456  -1.293  -1.238  -1.208  -1.048
34    -        -1.154  -1.094  -1.047  -0.906  -0.812  -0.767  -1.014  -0.958  -0.872
35    S         0.203   0.215   0.118   0.170   0.191   0.039   0.103   0.119  -0.049
36    S        -0.702  -0.714  -0.597  -0.744  -0.762  -0.583  -0.791  -0.801  -0.647
37    H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
38    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
39    Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
40    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
41    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
42    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
43    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
44    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
45    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
46    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
47    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
48    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
49    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
50    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
51    G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
52    Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
53    P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
54    A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
55    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
56    S        -0.164  -0.153  -0.058  -0.342  -0.352  -0.205  -0.460  -0.442  -0.318
57    Q         0.583   0.566   0.697   0.618   0.581   0.771   0.183   0.142   0.316
58    D         0.041   0.177   0.043   0.185   0.391   0.165  -0.139   0.063  -0.163
59    G        -1.249  -1.221  -1.091  -1.116  -1.082  -0.890  -1.104  -1.076  -0.912
60    N        -0.707  -0.751  -0.639  -0.552  -0.606  -0.441  -0.782  -0.835  -0.690
61    A         0.041  -0.032  -0.010   0.224   0.101   0.130  -0.139  -0.250  -0.243
62    F         0.030   0.010   0.019   0.131   0.099   0.103  -0.185  -0.214  -0.209
63    I         0.030  -0.010   0.012  -0.324  -0.396  -0.406  -0.185  -0.246  -0.221
64    P         1.900   1.907   2.044   2.053   2.065   2.279   2.113   2.124   2.347
65    E         0.139   0.136   0.077   0.349   0.346   0.256  -0.023  -0.029  -0.122
66    D         1.163   1.079   0.982   1.438   1.341   1.221   1.234   1.095   0.881
67    F         1.900   1.907   2.044   1.832   1.837   2.058   2.113   2.124   2.347
68    K         1.900   1.907   2.044   2.132   2.146   2.359   2.113   2.124   2.347
69    Y        -0.201  -0.271  -0.427   0.162   0.065  -0.150  -0.149  -0.241  -0.434
70    S        -0.201  -0.272  -0.443  -0.042  -0.136  -0.369  -0.149  -0.243  -0.454
71    T         0.139   0.217   0.116   0.166   0.294   0.145  -0.023   0.103  -0.057
72    V        -1.024  -0.984  -0.985  -0.874  -0.825  -0.788  -0.903  -0.871  -0.819
73    V         1.900   1.907   2.044   1.890   1.902   2.116   2.113   2.124   2.347
74    I        -0.474  -0.467  -0.529  -0.503  -0.503  -0.631  -0.526  -0.523  -0.569
75    S        -0.474  -0.504  -0.526  -0.396  -0.436  -0.434  -0.526  -0.570  -0.567
76    C         1.163   1.171   0.999   1.532   1.546   1.316   1.234   1.246   0.915
77    E        -0.201  -0.272  -0.443   0.209   0.106  -0.153  -0.149  -0.243  -0.454
78    P        -1.491  -1.516  -1.418  -1.465  -1.453  -1.313  -1.154  -1.168  -1.028
79    I        -1.491  -1.500  -1.402  -1.330  -1.355  -1.255  -1.154  -1.156  -1.015
80    I         0.139   0.199   0.082  -0.120  -0.026  -0.252  -0.023   0.049  -0.120
81    R         1.900   1.907   2.044   2.117   2.131   2.343   2.113   2.124   2.347
82    Q        -0.813  -0.892  -0.955  -0.358  -0.480  -0.590  -0.651  -0.740  -0.780
83    R        -1.491  -1.508  -1.398  -1.337  -1.329  -1.123  -1.154  -1.162  -1.012
84    F         1.900   1.907   2.044   1.832   1.837   2.058   2.113   2.124   2.347
85    M        -0.006   0.004   0.013  -0.494  -0.502  -0.445  -0.274  -0.271  -0.232
86    H        -0.134  -0.133  -0.058   0.117   0.117   0.226  -0.400  -0.401  -0.315
87    K        -0.201  -0.230  -0.418   0.331   0.293   0.047  -0.149  -0.187  -0.422
88    V         1.900   1.907   2.044   1.890   1.902   2.116   2.113   2.124   2.347
89    Y         1.900   1.907   2.044   1.999   2.011   2.226   2.113   2.124   2.347
90    S        -0.006  -0.052   0.017  -0.201  -0.251  -0.141  -0.274  -0.320  -0.224
91    L         0.606   0.661   0.740   0.017   0.147   0.205   0.228   0.333   0.406
92    L         1.163   1.162   0.994   0.881   0.881   0.665   1.234   1.231   0.905
93    S        -0.006  -0.006   0.024  -0.258  -0.248  -0.242  -0.274  -0.264  -0.215
94    C        -1.491  -1.475  -1.405  -1.418  -1.385  -1.258  -1.154  -1.135  -1.018
95    Q         1.900   1.907   2.044   2.085   2.098   2.311   2.113   2.124   2.347
96    L         0.800   0.840   0.814   0.306   0.375   0.286   0.605   0.676   0.557
97    L        -1.491  -1.464  -1.394  -1.690  -1.669  -1.511  -1.154  -1.130  -1.010
98    A        -1.024  -1.052  -1.002  -0.988  -1.041  -0.999  -0.903  -0.920  -0.831
99    S         0.800   0.861   0.799   0.724   0.826   0.670   0.605   0.714   0.525
100   L        -1.491  -1.516  -1.418  -1.684  -1.744  -1.568  -1.154  -1.168  -1.028
101   S        -0.813  -0.798  -0.653  -1.333  -1.310  -1.107  -0.903  -0.886  -0.706
102   F        -0.134  -0.076  -0.039  -0.268  -0.185  -0.128  -0.400  -0.315  -0.286
103   C         0.461   0.490   0.222   0.737   0.781   0.420   0.480   0.520   0.110
104   Y        -1.152  -1.141  -1.044  -1.306  -1.286  -1.157  -1.028  -1.017  -0.874
105   W        -0.474  -0.472  -0.528  -0.701  -0.698  -0.782  -0.526  -0.525  -0.571
106   A        -1.363  -1.407  -1.383  -1.381  -1.458  -1.432  -1.028  -1.069  -0.999
107   S        -1.024  -0.969  -0.980  -0.805  -0.727  -0.768  -0.903  -0.837  -0.809
108   V        -1.491  -1.479  -1.406  -1.605  -1.604  -1.443  -1.154  -1.139  -1.019
109   S        -1.024  -1.070  -0.992  -0.795  -0.836  -0.699  -0.903  -0.941  -0.824
110   T        -1.024  -0.947  -0.976  -0.731  -0.615  -0.665  -0.903  -0.822  -0.809
111   S        -0.685  -0.728  -0.605  -0.721  -0.768  -0.580  -0.777  -0.818  -0.659
112   L        -0.685  -0.666  -0.608  -1.193  -1.168  -1.042  -0.777  -0.755  -0.661
113   Q        -1.024  -1.027  -0.985  -0.652  -0.678  -0.598  -0.903  -0.907  -0.820
114   N        -1.830  -1.811  -1.711  -1.605  -1.597  -1.469  -1.280  -1.264  -1.121
115   F         0.606   0.610   0.721   0.566   0.565   0.709   0.228   0.231   0.367
116   I        -0.813  -0.773  -0.909  -0.702  -0.660  -0.820  -0.651  -0.613  -0.732
117   M        -1.491  -1.464  -1.387  -1.288  -1.254  -1.178  -1.154  -1.129  -1.005
118   S        -1.024  -1.021  -0.993  -0.884  -0.874  -0.794  -0.903  -0.898  -0.827
119   H        -0.006   0.004   0.036   0.241   0.274   0.340  -0.274  -0.248  -0.196
120   I        -0.685  -0.632  -0.586  -0.605  -0.521  -0.478  -0.777  -0.715  -0.637
121   A         0.800   0.821   0.796   0.977   1.011   0.924   0.605   0.640   0.520
122   L        -0.201  -0.272  -0.443  -0.354  -0.461  -0.681  -0.149  -0.243  -0.454
123   F        -1.491  -1.491  -1.388  -1.791  -1.812  -1.640  -1.154  -1.149  -1.006
124   Y        -0.685  -0.663  -0.585  -0.834  -0.804  -0.661  -0.777  -0.750  -0.637
125   I        -0.218  -0.208  -0.074  -0.798  -0.792  -0.604  -0.526  -0.513  -0.339
126   C        -1.024  -1.059  -1.018  -0.899  -0.942  -0.837  -0.903  -0.937  -0.849
127   M        -1.024  -0.973  -0.988  -1.208  -1.135  -1.190  -0.903  -0.857  -0.823
128   V        -0.557  -0.526  -0.530  -0.785  -0.735  -0.715  -0.651  -0.616  -0.579
129   V         0.139   0.110   0.057   0.145   0.076  -0.036  -0.023  -0.083  -0.158
130   S         0.461   0.441   0.206   0.545   0.528   0.202   0.480   0.450   0.085
131   L         0.606   0.651   0.737  -0.054   0.033   0.136   0.228   0.314   0.399
132   V        -0.006   0.021   0.037  -0.168  -0.121  -0.123  -0.274  -0.227  -0.191
133   S        -1.024  -1.059  -1.018  -0.957  -1.016  -0.928  -0.903  -0.937  -0.849
134   C        -0.218  -0.222  -0.092  -0.288  -0.322  -0.162  -0.526  -0.531  -0.364
135   I         0.461   0.386   0.186   0.363   0.264  -0.098   0.480   0.368   0.054
136   W        -0.685  -0.666  -0.608  -0.620  -0.591  -0.559  -0.777  -0.755  -0.661
137   L        -0.474  -0.393  -0.506  -0.701  -0.596  -0.690  -0.526  -0.426  -0.542
138   A        -1.152  -1.120  -1.047  -1.236  -1.220  -1.064  -1.028  -0.999  -0.877
139   V        -1.024  -1.013  -0.984  -0.881  -0.858  -0.819  -0.903  -0.894  -0.818
140   S         0.139   0.148   0.055   0.345   0.349   0.174  -0.023  -0.020  -0.157
141   P        -0.474  -0.415  -0.498  -0.208  -0.109  -0.205  -0.526  -0.442  -0.526
142   R        -1.024  -1.070  -1.008  -0.715  -0.793  -0.685  -0.903  -0.946  -0.840
143   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
144   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
145   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
146   Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
147   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
148   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
149   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
150   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
151   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
152   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
153   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
154   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
155   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
156   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
157   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
158   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
159   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
160   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
161   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
162   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
163   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
164   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
165   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
166   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
167   R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
168   R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
169   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
170   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
171   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
172   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
173   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
174   W        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
175   Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
176   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
177   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
178   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
179   S         1.900   1.907   2.044   1.804   1.823   2.030   2.113   2.124   2.347
180   Y         0.461   0.434   0.208   0.749   0.711   0.407   0.480   0.439   0.089
181   K         0.461   0.482   0.206   0.839   0.866   0.528   0.480   0.509   0.084
182   Q        -1.830  -1.800  -1.718  -1.616  -1.543  -1.505  -1.280  -1.255  -1.127
183   K         0.139   0.148   0.055   0.391   0.395   0.287  -0.023  -0.020  -0.157
184   L         0.139   0.096   0.049  -0.146  -0.210  -0.225  -0.023  -0.097  -0.171
185   T        -0.813  -0.797  -0.655  -1.257  -1.225  -1.027  -0.903  -0.885  -0.708
186   L         0.139   0.100   0.058  -0.258  -0.331  -0.379  -0.023  -0.090  -0.154
187   L         1.900   1.907   2.044   1.527   1.539   1.754   2.113   2.124   2.347
188   S        -0.557  -0.610  -0.554  -0.669  -0.744  -0.683  -0.651  -0.699  -0.603
189   I        -0.685  -0.683  -0.609  -0.952  -0.994  -0.906  -0.777  -0.781  -0.664
190   F         1.900   1.907   2.044   1.832   1.837   2.058   2.113   2.124   2.347
191   T         1.900   1.907   2.044   1.920   1.931   2.147   2.113   2.124   2.347
192   L        -0.474  -0.527  -0.510  -0.829  -0.887  -0.853  -0.526  -0.579  -0.549
193   S        -0.474  -0.500  -0.524  -0.365  -0.448  -0.521  -0.526  -0.567  -0.565
194   E         1.163   1.162   0.994   1.457   1.460   1.258   1.234   1.231   0.905
195   A         0.139   0.159   0.063   0.173   0.182   0.040  -0.023  -0.020  -0.146
196   Y         0.800   0.752   0.774   0.716   0.614   0.558   0.605   0.511   0.475
197   C        -1.024  -0.974  -0.992  -0.888  -0.833  -0.817  -0.903  -0.857  -0.825
198   L         0.139   0.200   0.084  -0.307  -0.228  -0.402  -0.023   0.052  -0.114
199   S         0.544   0.554   0.694   0.256   0.277   0.480   0.103   0.117   0.310
200   L        -0.557  -0.545  -0.533  -0.728  -0.707  -0.729  -0.651  -0.634  -0.581
201   V        -0.557  -0.548  -0.540  -0.566  -0.558  -0.515  -0.651  -0.640  -0.589
202   T        -0.685  -0.724  -0.611  -0.604  -0.682  -0.546  -0.777  -0.812  -0.665
203   L        -1.024  -1.036  -1.004  -1.251  -1.273  -1.214  -0.903  -0.914  -0.835
204   A        -0.557  -0.566  -0.539  -0.768  -0.796  -0.784  -0.651  -0.657  -0.589
205   Y        -0.685  -0.663  -0.604  -0.777  -0.737  -0.646  -0.777  -0.751  -0.656
206   D        -0.474  -0.499  -0.500  -0.191  -0.216  -0.221  -0.526  -0.539  -0.529
207   K        -0.813  -0.877  -0.958  -0.573  -0.664  -0.745  -0.651  -0.724  -0.783
208   D        -1.830  -1.817  -1.706  -1.256  -1.226  -1.083  -1.280  -1.267  -1.118
209   T        -0.218  -0.201  -0.079  -0.563  -0.539  -0.361  -0.526  -0.505  -0.346
210   V        -0.006   0.038   0.028  -0.340  -0.292  -0.326  -0.274  -0.236  -0.213
211   L         0.461   0.596   0.236   0.211   0.389  -0.122   0.480   0.670   0.130
212   S        -1.152  -1.148  -1.047  -1.061  -1.052  -0.917  -1.028  -1.020  -0.877
213   A         1.900   1.907   2.044   1.926   1.935   2.152   2.113   2.124   2.347
214   L         0.139   0.250   0.094  -0.052   0.136  -0.191  -0.023   0.136  -0.100
215   L        -0.813  -0.892  -0.955  -0.940  -1.061  -1.119  -0.651  -0.740  -0.780
216   I         0.461   0.504   0.226   0.408   0.483   0.057   0.480   0.538   0.115
217   T         1.900   1.907   2.044   1.920   1.931   2.147   2.113   2.124   2.347
218   T        -0.474  -0.409  -0.486  -0.790  -0.709  -0.793  -0.526  -0.452  -0.515
219   I        -0.685  -0.687  -0.592  -0.850  -0.840  -0.725  -0.777  -0.777  -0.645
220   V        -0.006   0.022   0.026  -0.340  -0.271  -0.312  -0.274  -0.225  -0.207
221   V         0.139   0.137   0.057   0.030   0.018  -0.131  -0.023  -0.028  -0.153
222   V        -0.006   0.015   0.030  -0.277  -0.226  -0.210  -0.274  -0.238  -0.205
223   G         0.461   0.386   0.186   0.701   0.603   0.293   0.480   0.368   0.054
224   V         0.139   0.128   0.063  -0.270  -0.284  -0.401  -0.023  -0.034  -0.142
225   S         0.800   0.816   0.817   0.724   0.750   0.706   0.605   0.631   0.562
226   L        -0.474  -0.466  -0.518  -0.849  -0.844  -0.924  -0.526  -0.531  -0.558
227   T         0.139   0.137   0.057   0.075   0.062  -0.057  -0.023  -0.028  -0.153
228   A         0.461   0.357   0.186   0.592   0.441   0.140   0.480   0.327   0.054
229   L        -0.006   0.002   0.009  -0.369  -0.371  -0.294  -0.274  -0.265  -0.232
230   S         0.606   0.610   0.721   0.501   0.506   0.644   0.228   0.231   0.367
231   E         0.139   0.080   0.066   0.202   0.118   0.085  -0.023  -0.098  -0.137
232   R         0.139   0.128   0.063   0.458   0.449   0.357  -0.023  -0.034  -0.142
233   F         0.139   0.080   0.066   0.249   0.174   0.148  -0.023  -0.098  -0.137
234   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
235   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
236   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
237   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
238   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
239   S         0.800   0.816   0.817   0.856   0.886   0.833   0.605   0.631   0.562
240   A         0.139   0.147   0.077   0.009   0.012  -0.136  -0.023  -0.009  -0.121
241   T        -0.474  -0.499  -0.500  -0.482  -0.490  -0.510  -0.526  -0.539  -0.529
242   S        -0.201  -0.297  -0.431   0.001  -0.115  -0.280  -0.149  -0.274  -0.439
243   I        -0.474  -0.527  -0.527  -0.335  -0.433  -0.475  -0.526  -0.585  -0.564
244   Y        -1.024  -1.034  -1.019  -0.701  -0.714  -0.679  -0.903  -0.903  -0.848
245   Y        -0.474  -0.471  -0.529  -0.299  -0.298  -0.382  -0.526  -0.524  -0.569
246   W        -1.024  -1.034  -1.019  -0.787  -0.798  -0.820  -0.903  -0.903  -0.848
247   L         0.800   0.888   0.869   0.367   0.503   0.462   0.605   0.764   0.664
248   N        -1.024  -1.013  -1.012  -0.736  -0.721  -0.722  -0.903  -0.888  -0.844
249   W        -1.024  -1.062  -1.011  -0.656  -0.716  -0.647  -0.903  -0.936  -0.841
250   G        -1.491  -1.493  -1.403  -1.214  -1.237  -1.080  -1.154  -1.153  -1.017
251   L         1.163   1.237   1.014   0.886   0.976   0.705   1.234   1.348   0.942
252   W         1.163   1.163   1.001   1.451   1.454   1.185   1.234   1.233   0.918
253   I        -1.024  -1.046  -0.994  -1.075  -1.115  -1.105  -0.903  -0.921  -0.828
254   M         0.800   0.802   0.809   0.436   0.439   0.459   0.605   0.605   0.546
255   I         1.163   1.163   1.001   1.063   1.074   0.846   1.234   1.233   0.918
256   G         0.461   0.386   0.186   0.619   0.508   0.133   0.480   0.368   0.054
257   M        -1.152  -1.145  -1.053  -0.921  -0.932  -0.802  -1.028  -1.016  -0.881
258   G        -0.201  -0.297  -0.431   0.093  -0.038  -0.263  -0.149  -0.274  -0.439
259   L        -0.006   0.005   0.033  -0.542  -0.527  -0.481  -0.274  -0.245  -0.198
260   T        -0.685  -0.674  -0.590  -0.940  -0.919  -0.800  -0.777  -0.760  -0.640
261   A        -1.491  -1.453  -1.381  -1.302  -1.269  -1.139  -1.154  -1.122  -1.001
262   L        -1.363  -1.407  -1.383  -1.174  -1.275  -1.338  -1.028  -1.069  -0.999
263   L         0.461   0.550   0.245   0.491   0.603   0.144   0.480   0.606   0.144
264   F        -0.474  -0.447  -0.520  -0.636  -0.620  -0.777  -0.526  -0.510  -0.561
265   G         0.139   0.128   0.063   0.358   0.351   0.270  -0.023  -0.034  -0.142
266   W        -1.024  -0.996  -0.986  -0.765  -0.757  -0.683  -0.903  -0.872  -0.819
267   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
268   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
269   H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
270   S        -0.474  -0.466  -0.518  -0.444  -0.449  -0.476  -0.526  -0.531  -0.558
271   S         0.461   0.357   0.186   0.555   0.427   0.188   0.480   0.327   0.054
272   K        -1.830  -1.808  -1.725  -1.322  -1.319  -1.195  -1.280  -1.262  -1.131
273   F        -1.363  -1.408  -1.366  -1.095  -1.196  -1.188  -1.028  -1.069  -0.984
274   N        -0.134  -0.159  -0.065  -0.007  -0.051   0.078  -0.400  -0.440  -0.325
275   L        -0.474  -0.429  -0.502  -0.700  -0.650  -0.703  -0.526  -0.482  -0.541
276   L        -1.024  -1.055  -0.991  -1.368  -1.417  -1.318  -0.903  -0.927  -0.823
277   Y         0.461   0.357   0.186   0.740   0.597   0.355   0.480   0.327   0.054
278   G        -0.134  -0.149  -0.070  -0.319  -0.344  -0.231  -0.400  -0.426  -0.332
279   W        -0.557  -0.509  -0.542  -0.404  -0.340  -0.396  -0.651  -0.605  -0.591
280   L        -0.685  -0.699  -0.604  -1.174  -1.189  -1.037  -0.777  -0.794  -0.659
281   G         1.163   1.171   0.999   1.347   1.365   1.135   1.234   1.246   0.915
282   A         0.461   0.357   0.186   0.650   0.506   0.253   0.480   0.327   0.054
283   I        -0.006   0.007   0.025  -0.574  -0.548  -0.497  -0.274  -0.252  -0.215
284   L        -0.218  -0.172  -0.064  -0.798  -0.713  -0.559  -0.526  -0.469  -0.326
285   F         1.900   1.907   2.044   1.832   1.837   2.058   2.113   2.124   2.347
286   T        -0.006  -0.061   0.003  -0.148  -0.200  -0.074  -0.274  -0.337  -0.242
287   A        -0.557  -0.546  -0.543  -0.667  -0.626  -0.619  -0.651  -0.635  -0.592
288   Y         1.900   1.907   2.044   1.999   2.011   2.226   2.113   2.124   2.347
289   L         0.800   0.816   0.817   0.433   0.468   0.387   0.605   0.631   0.562
290   F        -0.134  -0.075  -0.006  -0.740  -0.640  -0.553  -0.400  -0.316  -0.238
291   I        -0.557  -0.595  -0.538  -0.714  -0.750  -0.644  -0.651  -0.683  -0.587
292   D         1.900   1.907   2.044   2.056   2.071   2.282   2.113   2.124   2.347
293   T         1.900   1.907   2.044   1.920   1.931   2.147   2.113   2.124   2.347
294   Q         1.163   1.079   0.982   1.455   1.353   1.224   1.234   1.095   0.881
295   L        -1.024  -0.986  -0.987  -1.000  -0.965  -0.866  -0.903  -0.871  -0.821
296   I         1.163   1.171   0.999   1.072   1.094   0.861   1.234   1.246   0.915
297   F        -0.685  -0.694  -0.610  -0.902  -0.971  -0.874  -0.777  -0.789  -0.663
298   R         0.139   0.139   0.100   0.476   0.500   0.456  -0.023  -0.003  -0.082
299   K         0.139   0.139   0.100   0.399   0.430   0.359  -0.023  -0.003  -0.082
300   V        -0.134  -0.134  -0.058  -0.409  -0.404  -0.340  -0.400  -0.403  -0.314
301   Y        -0.813  -0.877  -0.958  -0.345  -0.465  -0.647  -0.651  -0.724  -0.783
302   P        -0.134  -0.082  -0.022  -0.318  -0.209  -0.174  -0.400  -0.327  -0.263
303   D         0.139   0.081   0.047   0.360   0.274   0.223  -0.023  -0.114  -0.170
304   E         0.139   0.209   0.110   0.388   0.503   0.370  -0.023   0.092  -0.066
305   E         0.461   0.377   0.183   0.783   0.666   0.359   0.480   0.356   0.049
306   V         0.606   0.637   0.728   0.217   0.277   0.395   0.228   0.285   0.381
307   R        -1.491  -1.471  -1.400  -1.063  -1.025  -0.939  -1.154  -1.136  -1.015
308   C        -0.557  -0.554  -0.552  -0.390  -0.393  -0.381  -0.651  -0.648  -0.602
309   A        -0.201  -0.154  -0.408   0.065   0.107  -0.228  -0.149  -0.097  -0.409
310   M        -0.218  -0.212  -0.091  -0.605  -0.593  -0.470  -0.526  -0.519  -0.362
311   M        -0.557  -0.549  -0.537  -0.542  -0.504  -0.481  -0.651  -0.638  -0.585
312   L         1.163   1.162   0.994   0.854   0.856   0.610   1.234   1.231   0.905
313   Y         1.900   1.907   2.044   1.999   2.011   2.226   2.113   2.124   2.347
314   L         1.163   1.163   1.001   0.881   0.883   0.676   1.234   1.233   0.918
315   D         1.900   1.907   2.044   2.056   2.071   2.282   2.113   2.124   2.347
316   I         1.163   1.079   0.982   1.063   0.962   0.814   1.234   1.095   0.881
317   V        -0.006   0.029   0.040  -0.540  -0.473  -0.448  -0.274  -0.227  -0.193
318   N         1.900   1.907   2.044   2.056   2.068   2.282   2.113   2.124   2.347
319   L         1.900   1.907   2.044   1.527   1.539   1.754   2.113   2.124   2.347
320   F         1.900   1.907   2.044   1.832   1.837   2.058   2.113   2.124   2.347
321   L         1.163   1.079   0.982   0.854   0.743   0.589   1.234   1.095   0.881
322   S        -1.491  -1.496  -1.402  -1.214  -1.201  -1.050  -1.154  -1.153  -1.015
323   I         1.163   1.237   1.014   1.072   1.173   0.884   1.234   1.348   0.942
324   L         1.900   1.907   2.044   1.527   1.539   1.754   2.113   2.124   2.347
325   R         1.163   1.079   0.982   1.499   1.400   1.279   1.234   1.095   0.881
326   I         1.900   1.907   2.044   1.716   1.738   1.943   2.113   2.124   2.347
327   L         1.163   1.139   0.994   0.911   0.886   0.727   1.234   1.194   0.904
328   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
329   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
330   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
331   N        -0.599  -0.626  -0.558  -0.454  -0.488  -0.379  -0.677  -0.705  -0.603
332   S        -0.557  -0.567  -0.547  -0.546  -0.553  -0.516  -0.651  -0.658  -0.596
333   N         0.461   0.463   0.220   0.842   0.847   0.544   0.480   0.482   0.106
334   D        -1.024  -1.045  -1.009  -0.633  -0.666  -0.615  -0.903  -0.924  -0.842
335   D         0.606   0.605   0.708   0.603   0.600   0.740   0.228   0.220   0.339
336   N        -0.006   0.016   0.036   0.116   0.157   0.213  -0.274  -0.236  -0.196
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P48558
Output conservation file - output/P48558
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
