1     M         1.410   1.457   1.556   1.615   1.680   1.835   1.542   1.610   1.770
2     T        -0.382  -0.278  -0.348  -0.292  -0.151  -0.260  -0.585  -0.445  -0.527
3     S         0.110   0.166   0.307  -0.045   0.047   0.256  -0.319  -0.234  -0.026
4     Q         0.356   0.506   0.419   0.204   0.427   0.305   0.146   0.398   0.192
5     L         0.704   0.678   0.504   0.470   0.448   0.238   0.728   0.682   0.352
6     N        -0.603  -0.665  -0.813  -0.518  -0.602  -0.788  -0.552  -0.624  -0.781
7     E         1.410   1.457   1.556   1.268   1.340   1.505   1.542   1.610   1.770
8     L         1.410   1.457   1.556   1.078   1.146   1.324   1.542   1.610   1.770
9     V         0.704   0.678   0.504   0.777   0.752   0.490   0.728   0.682   0.352
10    E        -0.540  -0.561  -0.423  -0.642  -0.665  -0.498  -0.784  -0.813  -0.625
11    F         1.410   1.457   1.556   1.534   1.601   1.758   1.542   1.610   1.770
12    L         0.704   0.581   0.493   0.450   0.292   0.172   0.728   0.524   0.332
13    H         0.704   0.581   0.493   1.041   0.871   0.723   0.728   0.524   0.332
14    S         0.704   0.612   0.498   0.820   0.711   0.487   0.728   0.576   0.340
15    P        -0.278  -0.325  -0.330  -0.192  -0.250  -0.309  -0.435  -0.481  -0.501
16    Q        -0.278  -0.397  -0.366  -0.038  -0.244  -0.182  -0.435  -0.615  -0.554
17    P         0.704   0.581   0.493   0.936   0.767   0.628   0.728   0.524   0.332
18    A         0.031  -0.196  -0.282   0.272  -0.027  -0.156   0.030  -0.288  -0.425
19    V         0.704   0.581   0.493   0.777   0.617   0.471   0.728   0.524   0.332
20    R        -0.603  -0.456  -0.784  -0.313  -0.117  -0.622  -0.552  -0.367  -0.747
21    Q         0.031  -0.196  -0.282   0.342  -0.004  -0.196   0.030  -0.288  -0.425
22    I        -0.278  -0.397  -0.366  -0.440  -0.720  -0.686  -0.435  -0.615  -0.554
23    A         1.410   1.457   1.556   1.465   1.530   1.692   1.542   1.610   1.770
24    I        -0.603  -0.738  -0.835  -0.748  -0.938  -1.046  -0.552  -0.718  -0.807
25    D        -0.278  -0.439  -0.366  -0.406  -0.640  -0.523  -0.435  -0.654  -0.554
26    N         0.031  -0.112  -0.260   0.333   0.159  -0.073   0.030  -0.169  -0.393
27    L         1.410   1.457   1.556   1.078   1.146   1.324   1.542   1.610   1.770
28    V         0.704   0.612   0.498   0.732   0.595   0.369   0.728   0.576   0.340
29    G         0.356   0.253   0.333   0.512   0.313   0.416   0.146  -0.065   0.025
30    F         0.110   0.166   0.307   0.039   0.130   0.339  -0.319  -0.234  -0.027
31    S         0.704   0.612   0.498   0.860   0.766   0.584   0.728   0.576   0.340
32    A        -0.620  -0.528  -0.407  -0.653  -0.524  -0.338  -0.901  -0.766  -0.604
33    G         0.031  -0.196  -0.282   0.391   0.076  -0.089   0.030  -0.288  -0.425
34    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
35    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
36    P         0.216   0.347   0.344   0.192   0.408   0.357  -0.112   0.113   0.047
37    T        -1.067  -0.954  -0.908  -0.850  -0.694  -0.620  -1.133  -1.002  -0.893
38    S        -1.392  -1.410  -1.302  -1.138  -1.156  -0.996  -1.250  -1.232  -1.070
39    K        -1.840  -1.758  -1.637  -1.719  -1.606  -1.430  -1.483  -1.385  -1.201
40    V        -0.945  -1.006  -0.881  -1.064  -1.162  -0.967  -1.017  -1.042  -0.866
41    F         0.704   0.612   0.498   0.957   0.856   0.714   0.728   0.576   0.340
42    K        -0.278  -0.250  -0.302  -0.265  -0.176  -0.289  -0.435  -0.366  -0.456
43    N        -1.717  -1.741  -1.644  -1.179  -1.231  -1.087  -1.366  -1.366  -1.205
44    D         0.110   0.165   0.306  -0.209  -0.112   0.106  -0.319  -0.235  -0.028
45    S        -0.865  -0.925  -0.887  -0.848  -1.021  -0.969  -0.901  -0.969  -0.872
46    Y         0.031  -0.196  -0.282   0.319  -0.021  -0.234   0.030  -0.288  -0.425
47    R        -1.392  -1.356  -1.294  -1.333  -1.264  -1.146  -1.250  -1.185  -1.063
48    P        -0.417  -0.421  -0.352  -0.402  -0.393  -0.253  -0.668  -0.655  -0.537
49    I        -0.278  -0.237  -0.330  -0.378  -0.350  -0.537  -0.435  -0.418  -0.504
50    K         0.031   0.282  -0.194   0.117   0.471  -0.266   0.030   0.376  -0.298
51    D         0.704   0.581   0.493   0.668   0.530   0.429   0.728   0.524   0.332
52    I         0.704   0.824   0.522   0.450   0.609   0.218   0.728   0.906   0.384
53    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
54    I         0.031   0.078  -0.228   0.174   0.255  -0.210   0.030   0.094  -0.347
55    K        -1.840  -1.844  -1.657  -1.652  -1.626  -1.363  -1.483  -1.443  -1.216
56    M        -0.603  -0.485  -0.779  -0.732  -0.581  -0.943  -0.552  -0.401  -0.742
57    I        -1.515  -1.448  -1.311  -1.496  -1.436  -1.226  -1.366  -1.272  -1.081
58    M        -1.190  -1.176  -1.254  -0.976  -0.992  -1.092  -1.017  -0.996  -1.024
59    D        -1.190  -0.977  -1.218  -1.133  -0.824  -1.173  -1.017  -0.774  -0.989
60    P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
61    E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
62    H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
63    G        -1.717  -1.640  -1.622  -1.404  -1.274  -1.260  -1.366  -1.277  -1.188
64    T        -1.067  -0.836  -0.876  -0.925  -0.578  -0.635  -1.133  -0.844  -0.856
65    R        -0.417  -0.446  -0.349  -0.463  -0.467  -0.314  -0.668  -0.674  -0.534
66    V         0.110   0.171   0.309  -0.074   0.013   0.228  -0.319  -0.224  -0.023
67    I        -0.865  -0.713  -0.830  -0.962  -0.686  -0.896  -0.901  -0.697  -0.807
68    I        -0.278  -0.289  -0.351  -0.296  -0.364  -0.427  -0.435  -0.495  -0.532
69    Q        -1.067  -0.996  -0.915  -1.056  -1.016  -0.869  -1.133  -1.049  -0.901
70    Q         0.031  -0.140  -0.269   0.418   0.198  -0.003   0.030  -0.209  -0.406
71    G        -0.417  -0.321  -0.352  -0.455  -0.331  -0.315  -0.668  -0.551  -0.537
72    V        -0.865  -0.731  -0.855  -0.979  -0.899  -0.996  -0.901  -0.776  -0.838
73    T         1.410   1.457   1.556   1.545   1.610   1.769   1.542   1.610   1.770
74    I        -0.603  -0.718  -0.824  -0.382  -0.528  -0.694  -0.552  -0.697  -0.794
75    L         1.410   1.457   1.556   1.078   1.146   1.324   1.542   1.610   1.770
76    V        -0.540  -0.570  -0.424  -0.675  -0.756  -0.547  -0.784  -0.824  -0.627
77    N         1.410   1.457   1.556   1.527   1.599   1.751   1.542   1.610   1.770
78    L         0.704   0.612   0.498   0.450   0.333   0.179   0.728   0.576   0.340
79    S        -0.278  -0.396  -0.351  -0.022  -0.190  -0.183  -0.435  -0.585  -0.533
80    E        -0.603  -0.738  -0.835  -0.570  -0.749  -0.905  -0.552  -0.718  -0.807
81    D         0.031  -0.196  -0.282   0.008  -0.308  -0.461   0.030  -0.288  -0.425
82    K        -1.840  -1.748  -1.642  -2.021  -1.848  -1.676  -1.483  -1.375  -1.205
83    L        -1.515  -1.428  -1.313  -1.690  -1.576  -1.430  -1.366  -1.250  -1.082
84    V        -0.417  -0.421  -0.352  -0.411  -0.445  -0.338  -0.668  -0.655  -0.537
85    R         0.356   0.279   0.333   0.289   0.086   0.093   0.146  -0.014   0.025
86    N        -0.865  -0.912  -0.861  -0.881  -0.951  -0.924  -0.901  -0.919  -0.841
87    I        -1.717  -1.751  -1.645  -1.760  -1.745  -1.566  -1.366  -1.373  -1.206
88    I        -0.417  -0.480  -0.356  -0.787  -0.904  -0.709  -0.668  -0.721  -0.543
89    L        -0.945  -0.898  -0.862  -1.017  -0.907  -0.885  -1.017  -0.936  -0.845
90    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
91    D        -1.497  -1.479  -1.332  -1.691  -1.602  -1.400  -1.345  -1.298  -1.096
92    D         0.704   0.678   0.504   0.648   0.632   0.398   0.728   0.682   0.352
93    K        -1.515  -1.384  -1.319  -1.699  -1.502  -1.372  -1.366  -1.214  -1.086
94    K        -0.603  -0.689  -0.822  -0.515  -0.622  -0.794  -0.552  -0.656  -0.792
95    F         0.704   0.833   0.524   0.935   1.098   0.703   0.728   0.919   0.388
96    L         0.704   0.678   0.504   0.450   0.423   0.189   0.728   0.682   0.352
97    K        -1.392  -1.406  -1.296  -1.236  -1.219  -1.086  -1.250  -1.237  -1.067
98    F        -1.717  -1.747  -1.644  -1.404  -1.528  -1.389  -1.366  -1.370  -1.205
99    L         0.356   0.294   0.342  -0.050  -0.159  -0.080   0.146   0.014   0.043
100   V        -1.840  -1.779  -1.646  -1.760  -1.732  -1.491  -1.483  -1.401  -1.208
101   W        -1.392  -1.415  -1.307  -0.958  -0.989  -0.872  -1.250  -1.244  -1.076
102   K        -1.717  -1.743  -1.652  -1.641  -1.784  -1.624  -1.366  -1.367  -1.212
103   I        -0.278  -0.385  -0.347  -0.378  -0.568  -0.571  -0.435  -0.568  -0.527
104   V        -1.067  -1.058  -0.907  -0.968  -0.941  -0.750  -1.133  -1.091  -0.892
105   D        -0.417  -0.474  -0.362  -0.658  -0.725  -0.556  -0.668  -0.709  -0.551
106   L        -0.865  -0.763  -0.873  -1.072  -0.939  -0.994  -0.901  -0.815  -0.857
107   T        -1.840  -1.681  -1.640  -1.867  -1.718  -1.575  -1.483  -1.321  -1.203
108   N         0.031  -0.196  -0.282   0.301  -0.015  -0.178   0.030  -0.288  -0.425
109   P        -2.165  -2.097  -1.939  -1.774  -1.702  -1.479  -1.599  -1.514  -1.305
110   N        -0.865  -0.876  -0.848  -0.763  -0.772  -0.778  -0.901  -0.876  -0.824
111   A         0.704   0.850   0.529   0.847   1.033   0.609   0.728   0.944   0.398
112   D         0.704   0.581   0.493   0.648   0.503   0.381   0.728   0.524   0.332
113   I         0.169   0.314   0.369  -0.363  -0.125  -0.037  -0.203   0.051   0.095
114   M         0.031  -0.112  -0.260   0.420   0.236   0.003   0.030  -0.169  -0.393
115   C         0.704   0.581   0.493   1.049   0.895   0.731   0.728   0.524   0.332
116   I         0.169   0.165   0.307   0.042   0.048   0.271  -0.203  -0.237  -0.026
117   L         1.410   1.457   1.556   1.078   1.146   1.324   1.542   1.610   1.770
118   L         1.410   1.457   1.556   1.078   1.146   1.324   1.542   1.610   1.770
119   S        -1.067  -1.062  -0.915  -0.989  -0.953  -0.740  -1.133  -1.096  -0.901
120   N         1.410   1.457   1.556   1.527   1.599   1.751   1.542   1.610   1.770
121   L         1.410   1.457   1.556   1.078   1.146   1.324   1.542   1.610   1.770
122   A         0.031   0.013  -0.231   0.253   0.223  -0.118   0.030  -0.010  -0.351
123   K         1.410   1.457   1.556   1.409   1.492   1.639   1.542   1.610   1.770
124   D        -1.067  -1.056  -0.904  -1.231  -1.166  -0.942  -1.133  -1.085  -0.889
125   D         0.704   0.612   0.498   0.609   0.491   0.295   0.728   0.576   0.340
126   G        -1.840  -1.753  -1.638  -1.535  -1.417  -1.254  -1.483  -1.378  -1.202
127   I         0.031  -0.196  -0.282   0.129  -0.207  -0.399   0.030  -0.288  -0.425
128   L        -1.717  -1.759  -1.645  -1.496  -1.600  -1.491  -1.366  -1.379  -1.206
129   A        -1.840  -1.681  -1.640  -1.680  -1.419  -1.386  -1.483  -1.321  -1.203
130   V        -0.540  -0.565  -0.423  -0.869  -0.955  -0.772  -0.784  -0.817  -0.625
131   L         0.110   0.177   0.314  -0.331  -0.263  -0.030  -0.319  -0.212  -0.013
132   N        -0.603  -0.305  -0.761  -0.586  -0.177  -0.822  -0.552  -0.174  -0.720
133   I        -1.392  -1.484  -1.313  -1.173  -1.274  -1.045  -1.250  -1.294  -1.081
134   K        -1.840  -1.757  -1.642  -1.783  -1.606  -1.499  -1.483  -1.380  -1.205
135   R        -1.515  -1.452  -1.314  -1.448  -1.342  -1.148  -1.366  -1.279  -1.083
136   N        -1.515  -1.345  -1.313  -1.517  -1.233  -1.196  -1.366  -1.188  -1.082
137   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
138   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
139   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
140   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
141   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
142   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
143   D        -1.088  -1.021  -0.930  -1.403  -1.301  -1.176  -1.138  -1.043  -0.914
144   D         0.148   0.210   0.312  -0.167  -0.068   0.097  -0.245  -0.147  -0.017
145   G        -0.372  -0.339  -0.380  -0.553  -0.497  -0.584  -0.542  -0.493  -0.566
146   L        -1.088  -1.007  -0.934  -1.400  -1.290  -1.169  -1.138  -1.028  -0.918
147   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
148   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
149   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
150   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
151   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
152   N        -1.356  -1.273  -1.290  -1.045  -0.946  -0.967  -1.193  -1.103  -1.058
153   K        -1.717  -1.724  -1.639  -1.480  -1.526  -1.380  -1.366  -1.353  -1.201
154   E        -0.417  -0.294  -0.338  -0.727  -0.546  -0.597  -0.668  -0.517  -0.520
155   V        -0.603  -0.712  -0.829  -0.486  -0.692  -0.899  -0.552  -0.690  -0.801
156   F         0.031  -0.196  -0.282   0.299  -0.017  -0.194   0.030  -0.288  -0.425
157   K        -0.278  -0.383  -0.349  -0.350  -0.522  -0.533  -0.435  -0.573  -0.530
158   S         0.704   0.581   0.493   0.820   0.663   0.478   0.728   0.524   0.332
159   L        -1.717  -1.619  -1.611  -1.688  -1.582  -1.609  -1.366  -1.260  -1.179
160   R        -0.417  -0.459  -0.357  -0.479  -0.507  -0.349  -0.668  -0.695  -0.544
161   A        -0.865  -0.892  -0.856  -0.923  -0.966  -0.966  -0.901  -0.895  -0.836
162   M         0.169   0.317   0.357   0.042   0.282   0.329  -0.203   0.057   0.072
163   D         0.704   0.581   0.493   0.648   0.503   0.381   0.728   0.524   0.332
164   C        -0.278  -0.397  -0.366   0.013  -0.186  -0.163  -0.435  -0.615  -0.554
165   L         1.410   1.457   1.556   1.078   1.146   1.324   1.542   1.610   1.770
166   M         1.410   1.457   1.556   1.615   1.680   1.835   1.542   1.610   1.770
167   D         1.410   1.457   1.556   1.256   1.330   1.494   1.542   1.610   1.770
168   C         0.356   0.253   0.333   0.427   0.164   0.210   0.146  -0.065   0.025
169   F         1.410   1.457   1.556   1.534   1.601   1.758   1.542   1.610   1.770
170   V         1.410   1.457   1.556   1.403   1.471   1.634   1.542   1.610   1.770
171   K         1.410   1.457   1.556   1.409   1.492   1.639   1.542   1.610   1.770
172   G         1.410   1.457   1.556   1.608   1.673   1.829   1.542   1.610   1.770
173   Y        -0.865  -0.891  -0.882  -0.620  -0.703  -0.668  -0.901  -0.938  -0.867
174   D         0.704   0.678   0.504   0.650   0.634   0.404   0.728   0.682   0.352
175   K        -0.865  -0.913  -0.885  -0.617  -0.689  -0.634  -0.901  -0.957  -0.870
176   K        -1.190  -1.200  -1.257  -0.965  -0.963  -1.079  -1.017  -1.026  -1.027
177   L         0.031  -0.196  -0.282  -0.135  -0.426  -0.531   0.030  -0.288  -0.425
178   T         0.704   0.824   0.522   0.920   1.079   0.677   0.728   0.906   0.384
179   K        -0.865  -0.803  -0.852  -0.981  -0.927  -1.021  -0.901  -0.829  -0.835
180   Y        -0.278  -0.356  -0.333  -0.044  -0.130  -0.129  -0.435  -0.525  -0.507
181   A         0.704   0.678   0.504   0.847   0.822   0.567   0.728   0.682   0.352
182   S        -0.865  -0.704  -0.839  -0.785  -0.588  -0.772  -0.901  -0.724  -0.820
183   F         0.169   0.187   0.308   0.163   0.178   0.343  -0.203  -0.192  -0.024
184   N         0.704   0.824   0.522   0.648   0.809   0.425   0.728   0.906   0.384
185   Y         0.704   0.612   0.498   0.987   0.884   0.696   0.728   0.576   0.340
186   L         1.410   1.457   1.556   1.078   1.146   1.324   1.542   1.610   1.770
187   A         0.169   0.215   0.317   0.015   0.086   0.223  -0.203  -0.137  -0.006
188   F        -0.278  -0.343  -0.335  -0.068  -0.145  -0.175  -0.435  -0.508  -0.509
189   F         0.356   0.253   0.333   0.394   0.182   0.275   0.146  -0.065   0.025
190   F         1.410   1.457   1.556   1.534   1.601   1.758   1.542   1.610   1.770
191   A         1.410   1.457   1.556   1.465   1.530   1.692   1.542   1.610   1.770
192   D         1.410   1.457   1.556   1.256   1.330   1.494   1.542   1.610   1.770
193   I        -0.945  -0.883  -0.862  -1.221  -1.137  -1.050  -1.017  -0.923  -0.845
194   S         0.704   0.612   0.498   0.860   0.766   0.584   0.728   0.576   0.340
195   R         0.704   0.581   0.493   0.903   0.738   0.586   0.728   0.524   0.332
196   F         0.031  -0.003  -0.238   0.361   0.317   0.010   0.030  -0.029  -0.362
197   K        -0.865  -0.862  -0.885  -0.981  -1.023  -1.088  -0.901  -0.910  -0.869
198   L        -1.515  -1.440  -1.319  -1.523  -1.414  -1.291  -1.366  -1.262  -1.086
199   G         0.704   0.581   0.493   0.981   0.816   0.657   0.728   0.524   0.332
200   R         1.410   1.457   1.556   1.529   1.591   1.753   1.542   1.610   1.770
201   M        -1.840  -1.847  -1.653  -1.690  -1.675  -1.404  -1.483  -1.445  -1.213
202   Y         1.410   1.457   1.556   1.595   1.673   1.817   1.542   1.610   1.770
203   F         1.410   1.457   1.556   1.534   1.601   1.758   1.542   1.610   1.770
204   I        -0.278  -0.427  -0.366  -0.290  -0.525  -0.434  -0.435  -0.643  -0.553
205   E        -0.417  -0.427  -0.342  -0.525  -0.470  -0.360  -0.668  -0.635  -0.518
206   E        -1.190  -1.193  -1.259  -1.132  -1.202  -1.236  -1.017  -1.019  -1.029
207   Q         1.410   1.457   1.556   1.604   1.670   1.825   1.542   1.610   1.770
208   E        -0.865  -0.908  -0.866  -0.973  -1.026  -0.964  -0.901  -0.914  -0.845
209   Y         1.410   1.457   1.556   1.595   1.673   1.817   1.542   1.610   1.770
210   D         1.410   1.457   1.556   1.256   1.330   1.494   1.542   1.610   1.770
211   G        -0.865  -0.950  -0.876  -0.726  -0.835  -0.779  -0.901  -0.962  -0.856
212   V         0.704   0.678   0.504   0.732   0.695   0.382   0.728   0.682   0.352
213   V        -0.417  -0.423  -0.352  -0.558  -0.553  -0.421  -0.668  -0.659  -0.537
214   P         1.410   1.457   1.556   1.554   1.613   1.777   1.542   1.610   1.770
215   I         0.031   0.026  -0.233   0.117   0.124  -0.333   0.030   0.015  -0.354
216   S         0.031  -0.140  -0.269   0.274   0.069  -0.135   0.030  -0.209  -0.406
217   K         1.410   1.457   1.556   1.409   1.492   1.639   1.542   1.610   1.770
218   L         0.031  -0.003  -0.238  -0.171  -0.223  -0.544   0.030  -0.029  -0.362
219   L         0.031  -0.196  -0.282  -0.170  -0.484  -0.611   0.030  -0.288  -0.425
220   V         0.704   0.678   0.504   0.799   0.775   0.541   0.728   0.682   0.352
221   F         1.410   1.457   1.556   1.534   1.601   1.758   1.542   1.610   1.770
222   T         1.410   1.457   1.556   1.545   1.610   1.769   1.542   1.610   1.770
223   E         1.410   1.457   1.556   1.268   1.340   1.505   1.542   1.610   1.770
224   K         0.565   0.440   0.395   0.599   0.424   0.335   0.508   0.282   0.145
225   Y        -0.278  -0.397  -0.366  -0.044  -0.233  -0.204  -0.435  -0.615  -0.554
226   D         0.356   0.253   0.333   0.126  -0.055   0.054   0.146  -0.065   0.025
227   A        -0.278  -0.059  -0.270  -0.264   0.086  -0.282  -0.435  -0.117  -0.412
228   K        -0.603  -0.846  -0.861  -0.511  -0.919  -1.019  -0.552  -0.838  -0.837
229   V        -0.865  -0.771  -0.837  -0.884  -0.759  -0.894  -0.901  -0.761  -0.812
230   R         1.410   1.457   1.556   1.529   1.591   1.753   1.542   1.610   1.770
231   R         1.410   1.457   1.556   1.529   1.591   1.753   1.542   1.610   1.770
232   E         0.031  -0.196  -0.282   0.047  -0.254  -0.388   0.030  -0.288  -0.425
233   G         1.410   1.457   1.556   1.608   1.673   1.829   1.542   1.610   1.770
234   V         1.410   1.457   1.556   1.403   1.471   1.634   1.542   1.610   1.770
235   A         1.410   1.457   1.556   1.465   1.530   1.692   1.542   1.610   1.770
236   S         0.031   0.058  -0.230   0.263   0.302  -0.098   0.030   0.056  -0.349
237   T         0.356   0.253   0.333   0.405   0.196   0.284   0.146  -0.065   0.025
238   I         1.410   1.457   1.556   1.405   1.483   1.636   1.542   1.610   1.770
239   K         1.410   1.457   1.556   1.409   1.492   1.639   1.542   1.610   1.770
240   N         1.410   1.457   1.556   1.527   1.599   1.751   1.542   1.610   1.770
241   S         0.031  -0.196  -0.282   0.231  -0.072  -0.253   0.030  -0.288  -0.425
242   L         0.031  -0.196  -0.282  -0.148  -0.451  -0.561   0.030  -0.288  -0.425
243   F         1.410   1.457   1.556   1.534   1.601   1.758   1.542   1.610   1.770
244   D         1.410   1.457   1.556   1.256   1.330   1.494   1.542   1.610   1.770
245   S        -0.540  -0.559  -0.422  -0.613  -0.660  -0.463  -0.784  -0.810  -0.623
246   E        -1.392  -1.294  -1.306  -1.422  -1.262  -1.265  -1.250  -1.144  -1.075
247   T        -1.840  -1.791  -1.649  -1.578  -1.512  -1.305  -1.483  -1.409  -1.210
248   H         0.704   0.612   0.498   1.060   0.943   0.777   0.728   0.576   0.340
249   E        -1.392  -1.481  -1.321  -1.320  -1.416  -1.175  -1.250  -1.291  -1.087
250   R        -1.392  -1.389  -1.301  -1.265  -1.268  -1.126  -1.250  -1.216  -1.070
251   L        -0.278  -0.249  -0.337  -0.579  -0.557  -0.613  -0.435  -0.439  -0.514
252   L         0.031  -0.112  -0.260  -0.132  -0.311  -0.493   0.030  -0.169  -0.393
253   K        -0.865  -0.883  -0.888  -0.885  -1.023  -1.053  -0.901  -0.929  -0.872
254   D        -0.278  -0.254  -0.346  -0.490  -0.537  -0.601  -0.435  -0.459  -0.525
255   E        -0.278  -0.363  -0.339  -0.418  -0.549  -0.517  -0.435  -0.535  -0.515
256   K        -0.945  -1.038  -0.888  -1.118  -1.223  -0.999  -1.017  -1.072  -0.873
257   I         0.704   0.581   0.493   0.779   0.626   0.472   0.728   0.524   0.332
258   N         1.410   1.457   1.556   1.527   1.599   1.751   1.542   1.610   1.770
259   L        -0.278  -0.376  -0.347  -0.634  -0.772  -0.708  -0.435  -0.560  -0.528
260   L         1.410   1.457   1.556   1.078   1.146   1.324   1.542   1.610   1.770
261   P         1.410   1.457   1.556   1.554   1.613   1.777   1.542   1.610   1.770
262   Y         0.356   0.405   0.371   0.494   0.574   0.469   0.146   0.219   0.099
263   I         0.704   0.612   0.498   0.734   0.608   0.371   0.728   0.576   0.340
264   L         0.704   0.678   0.504   0.483   0.463   0.268   0.728   0.682   0.352
265   L         1.410   1.457   1.556   1.078   1.146   1.324   1.542   1.610   1.770
266   P         1.410   1.457   1.556   1.554   1.613   1.777   1.542   1.610   1.770
267   I         0.110   0.166   0.307  -0.432  -0.350  -0.119  -0.319  -0.234  -0.027
268   A         0.704   0.581   0.493   0.869   0.718   0.600   0.728   0.524   0.332
269   S         0.169   0.314   0.369   0.140   0.400   0.444  -0.203   0.051   0.095
270   A        -0.417  -0.427  -0.342  -0.384  -0.353  -0.224  -0.668  -0.635  -0.518
271   K         0.169   0.314   0.369  -0.190   0.064   0.128  -0.203   0.051   0.095
272   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
273   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
274   E         0.704   0.581   0.493   0.641   0.484   0.346   0.728   0.524   0.332
275   I        -0.382  -0.490  -0.377  -0.602  -0.775  -0.641  -0.585  -0.718  -0.568
276   D         0.031  -0.196  -0.282   0.047  -0.246  -0.372   0.030  -0.288  -0.425
277   E         0.704   0.678   0.504   0.663   0.644   0.418   0.728   0.682   0.352
278   E         0.169   0.217   0.319  -0.275  -0.201  -0.057  -0.203  -0.134  -0.002
279   D         0.169   0.182   0.307  -0.279  -0.279  -0.085  -0.203  -0.202  -0.026
280   M         0.031  -0.140  -0.269   0.378   0.137  -0.105   0.030  -0.209  -0.406
281   F         0.031  -0.196  -0.282   0.213  -0.159  -0.394   0.030  -0.288  -0.425
282   N        -0.865  -1.008  -0.891  -0.815  -1.044  -0.910  -0.901  -1.033  -0.875
283   L         0.356   0.253   0.333   0.025  -0.124   0.036   0.146  -0.065   0.025
284   P         0.031  -0.196  -0.282   0.278  -0.080  -0.270   0.030  -0.288  -0.425
285   D        -0.278  -0.363  -0.339  -0.486  -0.590  -0.578  -0.435  -0.535  -0.515
286   E         0.704   0.581   0.493   0.619   0.452   0.294   0.728   0.524   0.332
287   L         1.410   1.457   1.556   1.078   1.146   1.324   1.542   1.610   1.770
288   Q         1.410   1.457   1.556   1.604   1.670   1.825   1.542   1.610   1.770
289   L         1.410   1.457   1.556   1.078   1.146   1.324   1.542   1.610   1.770
290   L         1.410   1.457   1.556   1.078   1.146   1.324   1.542   1.610   1.770
291   P         0.704   0.678   0.504   0.947   0.915   0.673   0.728   0.682   0.352
292   E        -1.515  -1.414  -1.315  -1.565  -1.395  -1.264  -1.366  -1.242  -1.083
293   D         1.410   1.457   1.556   1.256   1.330   1.494   1.542   1.610   1.770
294   K         1.410   1.457   1.556   1.409   1.492   1.639   1.542   1.610   1.770
295   E        -1.392  -1.362  -1.294  -1.328  -1.235  -1.136  -1.250  -1.188  -1.063
296   R         1.410   1.457   1.556   1.529   1.591   1.753   1.542   1.610   1.770
297   D         0.169   0.188   0.309  -0.279  -0.265  -0.081  -0.203  -0.190  -0.022
298   P         0.704   0.678   0.504   0.909   0.870   0.583   0.728   0.682   0.352
299   I        -1.067  -0.834  -0.882  -1.412  -1.025  -1.155  -1.133  -0.843  -0.865
300   P        -1.392  -1.395  -1.303  -1.211  -1.242  -1.118  -1.250  -1.228  -1.073
301   A        -1.840  -1.757  -1.638  -1.705  -1.579  -1.427  -1.483  -1.382  -1.202
302   I         0.031   0.019  -0.235   0.128   0.129  -0.314   0.030  -0.001  -0.357
303   I        -0.865  -0.749  -0.852  -0.850  -0.687  -0.868  -0.901  -0.788  -0.834
304   C         0.031  -0.196  -0.282   0.372   0.020  -0.218   0.030  -0.288  -0.425
305   C        -0.865  -0.586  -0.811  -0.690  -0.277  -0.597  -0.901  -0.549  -0.782
306   H         0.704   0.612   0.498   0.990   0.844   0.608   0.728   0.576   0.340
307   L         0.704   0.612   0.498   0.450   0.333   0.179   0.728   0.576   0.340
308   E         1.410   1.457   1.556   1.268   1.340   1.505   1.542   1.610   1.770
309   S         0.356   0.253   0.333   0.374   0.203   0.300   0.146  -0.065   0.025
310   I         0.169   0.314   0.369  -0.363  -0.125  -0.037  -0.203   0.051   0.095
311   L         0.031  -0.196  -0.282  -0.145  -0.449  -0.553   0.030  -0.288  -0.425
312   L         1.410   1.457   1.556   1.078   1.146   1.324   1.542   1.610   1.770
313   L         1.410   1.457   1.556   1.078   1.146   1.324   1.542   1.610   1.770
314   C         0.169   0.165   0.307   0.232   0.183   0.392  -0.203  -0.237  -0.026
315   T         0.704   0.612   0.498   0.927   0.808   0.628   0.728   0.576   0.340
316   T         0.704   0.678   0.504   0.927   0.901   0.639   0.728   0.682   0.352
317   H        -0.278  -0.052  -0.274  -0.151   0.186  -0.126  -0.435  -0.103  -0.416
318   A         0.110   0.166   0.307  -0.247  -0.168   0.060  -0.319  -0.234  -0.027
319   G        -0.417  -0.357  -0.330  -0.340  -0.205  -0.166  -0.668  -0.548  -0.503
320   R         1.410   1.457   1.556   1.529   1.591   1.753   1.542   1.610   1.770
321   E         0.704   0.581   0.493   0.619   0.452   0.294   0.728   0.524   0.332
322   Y        -0.603  -0.718  -0.824  -0.246  -0.451  -0.635  -0.552  -0.697  -0.794
323   L         0.110   0.198   0.324  -0.267  -0.044   0.134  -0.319  -0.170   0.006
324   R         1.410   1.457   1.556   1.529   1.591   1.753   1.542   1.610   1.770
325   D        -1.392  -1.363  -1.290  -1.377  -1.275  -1.221  -1.250  -1.186  -1.060
326   K         0.031  -0.196  -0.282   0.185  -0.114  -0.276   0.030  -0.288  -0.425
327   S         0.031   0.026  -0.233   0.255   0.255  -0.119   0.030   0.015  -0.354
328   V         1.410   1.457   1.556   1.403   1.471   1.634   1.542   1.610   1.770
329   Y         1.410   1.457   1.556   1.595   1.673   1.817   1.542   1.610   1.770
330   P         0.704   0.833   0.524   0.936   1.094   0.680   0.728   0.919   0.388
331   L         0.110   0.201   0.328  -0.432  -0.213  -0.029  -0.319  -0.164   0.014
332   V         0.110   0.168   0.308  -0.192  -0.098   0.119  -0.319  -0.231  -0.025
333   R         0.704   0.833   0.524   0.903   1.068   0.640   0.728   0.919   0.388
334   E         1.410   1.457   1.556   1.268   1.340   1.505   1.542   1.610   1.770
335   L         0.031   0.019  -0.235  -0.106  -0.130  -0.404   0.030  -0.001  -0.357
336   H         1.410   1.457   1.556   1.660   1.719   1.878   1.542   1.610   1.770
337   K         0.356   0.253   0.333   0.170  -0.073  -0.010   0.146  -0.065   0.025
338   N        -0.603  -0.537  -0.795  -0.292  -0.211  -0.604  -0.552  -0.478  -0.761
339   V        -0.865  -0.705  -0.832  -0.770  -0.524  -0.677  -0.901  -0.685  -0.808
340   E        -0.865  -0.897  -0.884  -0.995  -1.081  -0.983  -0.901  -0.944  -0.868
341   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
342   N        -0.865  -0.587  -0.813  -0.988  -0.578  -0.917  -0.901  -0.549  -0.785
343   E         0.031   0.119  -0.223   0.032   0.163  -0.328   0.030   0.147  -0.339
344   D        -1.392  -1.415  -1.307  -1.475  -1.503  -1.284  -1.250  -1.244  -1.076
345   I         0.169   0.217   0.319  -0.071   0.005   0.143  -0.203  -0.134  -0.002
346   G        -1.392  -1.324  -1.302  -1.067  -0.990  -0.963  -1.250  -1.172  -1.072
347   E         0.169   0.217   0.319  -0.275  -0.201  -0.057  -0.203  -0.134  -0.002
348   L        -0.603  -0.846  -0.861  -0.738  -1.081  -1.059  -0.552  -0.838  -0.837
349   C         0.704   0.869   0.526   1.050   1.266   0.788   0.728   0.971   0.392
350   Y        -0.865  -0.779  -0.846  -0.893  -0.802  -0.834  -0.901  -0.781  -0.823
351   R         0.704   0.612   0.498   0.930   0.818   0.660   0.728   0.576   0.340
352   I        -0.620  -0.537  -0.405  -1.104  -1.006  -0.785  -0.901  -0.778  -0.601
353   V         1.410   1.457   1.556   1.403   1.471   1.634   1.542   1.610   1.770
354   N         0.110   0.166   0.307   0.041   0.127   0.341  -0.319  -0.234  -0.027
355   M         0.704   0.581   0.493   0.988   0.821   0.663   0.728   0.524   0.332
356   L         1.410   1.457   1.556   1.078   1.146   1.324   1.542   1.610   1.770
357   M         0.031   0.026  -0.233   0.369   0.353  -0.059   0.030   0.015  -0.354
358   R         1.410   1.457   1.556   1.529   1.591   1.753   1.542   1.610   1.770
359   G         0.169   0.314   0.369  -0.090   0.132   0.221  -0.203   0.051   0.095
360   E         0.704   0.850   0.529   0.619   0.818   0.359   0.728   0.944   0.398
361   P        -0.417  -0.308  -0.348  -0.413  -0.300  -0.305  -0.668  -0.547  -0.534
362   G        -1.515  -1.436  -1.308  -1.439  -1.346  -1.134  -1.366  -1.263  -1.078
363   A        -1.840  -1.688  -1.643  -1.726  -1.526  -1.428  -1.483  -1.330  -1.205
364   G        -1.840  -1.605  -1.635  -1.649  -1.393  -1.329  -1.483  -1.262  -1.200
365   A        -1.392  -1.475  -1.310  -1.406  -1.588  -1.340  -1.250  -1.285  -1.077
366   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
367   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
368   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
369   M        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
370   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
371   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
372   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
373   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
374   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
375   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
376   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
377   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
378   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
379   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
380   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
381   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
382   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
383   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
384   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
385   E        -0.985  -0.929  -0.881  -1.236  -1.158  -1.057  -1.041  -0.964  -0.864
386   S        -1.868  -1.751  -1.640  -1.791  -1.625  -1.453  -1.497  -1.368  -1.202
387   E        -1.356  -1.391  -1.304  -1.391  -1.421  -1.313  -1.193  -1.211  -1.071
388   E        -1.392  -1.407  -1.297  -1.369  -1.337  -1.197  -1.250  -1.238  -1.068
389   E        -1.392  -1.416  -1.297  -1.577  -1.608  -1.421  -1.250  -1.245  -1.068
390   E        -0.603  -0.846  -0.861  -0.546  -0.882  -0.909  -0.552  -0.838  -0.837
391   D        -1.392  -1.484  -1.313  -1.373  -1.469  -1.257  -1.250  -1.294  -1.081
392   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
393   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
394   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
395   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
396   D        -1.190  -1.315  -1.286  -1.164  -1.343  -1.315  -1.017  -1.137  -1.054
397   D         0.031  -0.003  -0.238  -0.002  -0.062  -0.411   0.030  -0.029  -0.362
398   E        -0.417  -0.354  -0.326  -0.781  -0.626  -0.588  -0.668  -0.543  -0.498
399   E         0.169   0.213   0.319  -0.279  -0.212  -0.060  -0.203  -0.141  -0.003
400   D         1.410   1.457   1.556   1.256   1.330   1.494   1.542   1.610   1.770
401   E        -1.515  -1.525  -1.323  -1.679  -1.712  -1.416  -1.366  -1.329  -1.090
402   I        -0.278  -0.133  -0.301  -0.378  -0.155  -0.476  -0.435  -0.243  -0.460
403   V         0.704   0.850   0.529   0.808   0.989   0.601   0.728   0.944   0.398
404   E         1.410   1.457   1.556   1.268   1.340   1.505   1.542   1.610   1.770
405   V         0.356   0.517   0.426   0.269   0.522   0.351   0.146   0.416   0.206
406   A        -1.497  -1.498  -1.327  -1.775  -1.786  -1.526  -1.345  -1.311  -1.093
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P48362
Output conservation file - output/P48362
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
