1     M         2.012   2.044   2.124   2.256   2.307   2.432   2.243   2.291   2.428
2     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
19    N        -0.058  -0.090  -0.043  -0.267  -0.326  -0.268  -0.295  -0.344  -0.290
20    V         0.652   0.705   0.760   0.585   0.695   0.749   0.254   0.344   0.403
21    Q        -0.530  -0.619  -0.569  -0.492  -0.620  -0.564  -0.574  -0.659  -0.593
22    D         2.012   2.044   2.124   2.068   2.112   2.242   2.243   2.291   2.428
23    R         2.012   2.044   2.124   2.157   2.200   2.333   2.243   2.291   2.428
24    R         2.012   2.044   2.124   2.157   2.200   2.333   2.243   2.291   2.428
25    R         2.012   2.044   2.124   2.157   2.200   2.333   2.243   2.291   2.428
26    L         0.109   0.033   0.045  -0.113  -0.250  -0.240  -0.077  -0.187  -0.176
27    L         1.195   1.086   1.022   1.174   1.034   0.932   1.249   1.059   0.917
28    G         2.012   2.044   2.124   2.013   2.057   2.187   2.243   2.291   2.428
29    P         2.012   2.044   2.124   2.164   2.204   2.339   2.243   2.291   2.428
30    A        -0.136  -0.118  -0.058  -0.440  -0.424  -0.346  -0.409  -0.385  -0.311
31    A        -1.468  -1.398  -1.404  -1.396  -1.273  -1.312  -1.071  -1.004  -0.980
32    A         0.427   0.343   0.199   0.645   0.512   0.335   0.420   0.292   0.071
33    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
34    K        -0.925  -0.985  -1.008  -0.823  -0.921  -1.008  -0.740  -0.802  -0.804
35    P         2.012   2.044   2.124   2.164   2.204   2.339   2.243   2.291   2.428
36    M        -0.640  -0.667  -0.605  -0.518  -0.544  -0.438  -0.680  -0.711  -0.630
37    A        -1.192  -1.164  -1.093  -1.218  -1.189  -1.072  -1.005  -0.973  -0.883
38    F         0.120   0.008   0.032   0.344   0.167   0.175  -0.031  -0.199  -0.180
39    S        -0.058  -0.099  -0.043  -0.353  -0.421  -0.335  -0.295  -0.358  -0.290
40    N        -0.285  -0.298  -0.439  -0.104  -0.114  -0.341  -0.243  -0.264  -0.431
41    T        -0.530  -0.528  -0.527  -0.641  -0.637  -0.623  -0.574  -0.561  -0.544
42    T        -1.073  -1.056  -1.022  -0.949  -0.938  -0.863  -0.906  -0.882  -0.823
43    T        -0.925  -0.783  -0.938  -0.738  -0.503  -0.799  -0.740  -0.580  -0.733
44    H        -1.862  -1.839  -1.765  -1.544  -1.516  -1.402  -1.237  -1.212  -1.120
45    V        -1.862  -1.839  -1.765  -1.551  -1.519  -1.409  -1.237  -1.212  -1.120
46    P        -1.073  -1.049  -1.019  -0.830  -0.795  -0.746  -0.906  -0.875  -0.821
47    E        -0.925  -0.924  -0.985  -0.863  -0.890  -1.008  -0.740  -0.738  -0.781
48    K        -1.468  -1.404  -1.401  -1.309  -1.186  -1.215  -1.071  -1.010  -0.977
49    K        -0.530  -0.563  -0.547  -0.547  -0.578  -0.588  -0.574  -0.600  -0.572
50    S        -1.073  -1.087  -1.020  -1.099  -1.105  -1.005  -0.906  -0.910  -0.822
51    T        -1.468  -1.470  -1.405  -1.167  -1.206  -1.069  -1.071  -1.067  -0.981
52    D         0.109   0.056   0.066   0.104   0.025   0.031  -0.077  -0.136  -0.137
53    L         0.892   0.856   0.872   0.814   0.736   0.738   0.720   0.640   0.628
54    T        -0.640  -0.630  -0.581  -0.617  -0.609  -0.535  -0.680  -0.668  -0.603
55    P         0.120   0.048   0.053   0.054  -0.069  -0.087  -0.031  -0.141  -0.149
56    K        -0.640  -0.648  -0.589  -0.592  -0.609  -0.524  -0.680  -0.688  -0.611
57    G        -1.192  -1.172  -1.093  -1.259  -1.204  -1.114  -1.005  -0.980  -0.883
58    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
59    N        -1.095  -1.102  -1.041  -1.010  -1.022  -0.932  -0.915  -0.918  -0.836
60    E        -0.635  -0.582  -0.574  -0.854  -0.759  -0.752  -0.689  -0.630  -0.601
61    S        -1.555  -1.530  -1.457  -1.576  -1.519  -1.434  -1.140  -1.112  -1.021
62    E        -0.530  -0.421  -0.523  -0.641  -0.480  -0.619  -0.574  -0.438  -0.539
63    Q        -1.073  -1.059  -1.030  -0.824  -0.812  -0.741  -0.906  -0.884  -0.830
64    E         0.013   0.064   0.049  -0.264  -0.195  -0.189  -0.243  -0.184  -0.181
65    L        -1.073  -1.021  -1.016  -0.945  -0.850  -0.860  -0.906  -0.853  -0.818
66    S        -0.285  -0.280  -0.448   0.067   0.087  -0.205  -0.243  -0.242  -0.443
67    L         0.427   0.408   0.226   0.423   0.395   0.109   0.420   0.391   0.112
68    H         0.109   0.203   0.084   0.173   0.317   0.118  -0.077   0.065  -0.109
69    T         0.427   0.521   0.233   0.593   0.724   0.313   0.420   0.556   0.123
70    G         0.427   0.492   0.230   0.523   0.613   0.211   0.420   0.515   0.118
71    F        -0.679  -0.641  -0.606  -0.781  -0.738  -0.693  -0.740  -0.693  -0.636
72    I         0.013  -0.047   0.029  -0.240  -0.320  -0.197  -0.243  -0.304  -0.205
73    E        -1.073  -1.075  -1.025  -0.941  -0.946  -0.858  -0.906  -0.901  -0.826
74    N         1.195   1.086   1.022   1.251   1.114   0.973   1.249   1.059   0.917
75    C         0.821   0.909   0.873   0.846   0.964   0.925   0.586   0.739   0.631
76    N         1.195   1.086   1.022   1.251   1.114   0.973   1.249   1.059   0.917
77    G         2.012   2.044   2.124   2.013   2.057   2.187   2.243   2.291   2.428
78    S         2.012   2.044   2.124   1.787   1.839   1.959   2.243   2.291   2.428
79    A         1.195   1.253   1.044   1.277   1.346   1.039   1.249   1.338   0.959
80    L         0.821   0.909   0.873   0.903   1.058   0.958   0.586   0.739   0.631
81    V         0.821   0.909   0.873   0.605   0.743   0.669   0.586   0.739   0.631
82    E         2.012   2.044   2.124   2.039   2.088   2.213   2.243   2.291   2.428
83    A        -0.925  -0.866  -0.933  -0.861  -0.792  -0.872  -0.740  -0.673  -0.728
84    R        -0.748  -0.714  -0.647  -0.670  -0.620  -0.520  -0.802  -0.761  -0.676
85    S         0.632   0.661   0.744   0.244   0.275   0.403   0.213   0.254   0.369
86    L        -0.748  -0.714  -0.647  -1.034  -1.010  -0.887  -0.802  -0.761  -0.676
87    G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
88    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
89    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
90    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
91    H        -1.073  -1.074  -1.039  -0.895  -0.934  -0.882  -0.906  -0.899  -0.837
92    Q        -0.530  -0.586  -0.563  -0.356  -0.447  -0.425  -0.574  -0.632  -0.590
93    T        -0.285  -0.402  -0.466  -0.179  -0.388  -0.506  -0.243  -0.390  -0.464
94    S        -0.679  -0.637  -0.610  -1.023  -0.917  -0.899  -0.740  -0.690  -0.640
95    L         0.013   0.049   0.027  -0.317  -0.273  -0.281  -0.243  -0.199  -0.207
96    I        -1.073  -1.121  -1.059  -1.123  -1.215  -1.093  -0.906  -0.938  -0.855
97    T        -1.073  -1.121  -1.059  -1.024  -1.073  -0.995  -0.906  -0.938  -0.855
98    A         0.427   0.429   0.234   0.312   0.311   0.020   0.420   0.420   0.124
99    V         1.195   1.240   1.045   1.241   1.294   1.018   1.249   1.316   0.961
100   Y        -0.136  -0.126  -0.050   0.070   0.090   0.204  -0.409  -0.399  -0.302
101   G         2.012   2.044   2.124   2.013   2.057   2.187   2.243   2.291   2.428
102   P         2.012   2.044   2.124   2.164   2.204   2.339   2.243   2.291   2.428
103   R         1.195   1.287   1.054   1.430   1.546   1.241   1.249   1.392   0.978
104   S         0.109   0.072   0.074   0.094   0.057   0.031  -0.077  -0.110  -0.123
105   I        -0.530  -0.542  -0.540  -0.660  -0.675  -0.656  -0.574  -0.590  -0.566
106   R         1.195   1.086   1.022   1.446   1.299   1.220   1.249   1.059   0.917
107   G         1.195   1.086   1.022   1.302   1.159   1.078   1.249   1.059   0.917
108   S         1.195   1.147   1.042   1.033   0.973   0.808   1.249   1.163   0.955
109   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
110   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
111   F         2.012   2.044   2.124   2.214   2.268   2.390   2.243   2.291   2.428
112   T        -0.530  -0.558  -0.550  -0.614  -0.672  -0.644  -0.574  -0.596  -0.572
113   S        -0.530  -0.619  -0.569  -0.668  -0.776  -0.686  -0.574  -0.659  -0.593
114   Q        -1.073  -1.121  -1.059  -0.785  -0.852  -0.772  -0.906  -0.938  -0.855
115   G         0.427   0.375   0.209   0.567   0.466   0.224   0.420   0.337   0.087
116   T         0.109   0.099   0.053  -0.219  -0.271  -0.316  -0.077  -0.122  -0.164
117   I        -0.530  -0.428  -0.509  -0.635  -0.495  -0.593  -0.574  -0.453  -0.530
118   S         1.195   1.147   1.042   1.053   1.001   0.844   1.249   1.163   0.955
119   I        -0.530  -0.586  -0.563  -0.659  -0.752  -0.694  -0.574  -0.632  -0.590
120   Q        -0.530  -0.567  -0.562  -0.276  -0.324  -0.315  -0.574  -0.615  -0.589
121   L        -1.073  -1.121  -1.059  -0.876  -0.954  -0.840  -0.906  -0.938  -0.855
122   K         2.012   2.044   2.124   2.061   2.113   2.236   2.243   2.291   2.428
123   -         2.012   2.044   2.124   2.240   2.293   2.416   2.243   2.291   2.428
124   -         0.892   0.840   0.859   0.757   0.659   0.685   0.720   0.609   0.604
125   -         2.012   2.044   2.124   2.136   2.178   2.311   2.243   2.291   2.428
126   -        -0.748  -0.724  -0.647  -0.464  -0.448  -0.312  -0.802  -0.772  -0.676
127   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
128   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
129   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
130   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
131   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
132   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
133   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
134   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
135   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
136   N         0.285   0.223   0.120   0.365   0.288   0.108   0.213   0.116  -0.047
137   G        -0.002  -0.019   0.007  -0.102  -0.153  -0.094  -0.238  -0.267  -0.229
138   L        -0.635  -0.658  -0.594  -0.772  -0.813  -0.695  -0.689  -0.706  -0.621
139   L        -0.530  -0.565  -0.559  -0.687  -0.760  -0.739  -0.574  -0.612  -0.586
140   E         0.013  -0.011   0.020  -0.160  -0.197  -0.159  -0.243  -0.261  -0.214
141   K        -0.925  -0.890  -0.971  -0.719  -0.661  -0.804  -0.740  -0.698  -0.767
142   Y        -1.073  -1.003  -1.035  -0.729  -0.623  -0.683  -0.906  -0.832  -0.834
143   N        -0.925  -0.984  -0.972  -0.765  -0.846  -0.852  -0.740  -0.801  -0.768
144   -        -0.748  -0.724  -0.647  -0.793  -0.748  -0.644  -0.802  -0.772  -0.676
145   -        -0.058  -0.015   0.002  -0.095  -0.018  -0.007  -0.295  -0.236  -0.224
146   -         0.632   0.665   0.746   0.550   0.623   0.741   0.213   0.264   0.373
147   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
148   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
149   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
150   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
151   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
152   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
153   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
154   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
155   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
156   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
157   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
158   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
159   T        -0.530  -0.586  -0.534  -0.648  -0.736  -0.669  -0.574  -0.631  -0.559
160   N        -0.925  -0.976  -0.981  -0.762  -0.842  -0.863  -0.740  -0.793  -0.777
161   E         0.013  -0.011   0.020  -0.240  -0.277  -0.230  -0.243  -0.261  -0.214
162   L        -0.530  -0.512  -0.542  -0.572  -0.513  -0.574  -0.574  -0.540  -0.562
163   K        -0.285  -0.310  -0.454   0.058   0.019  -0.147  -0.243  -0.278  -0.449
164   E        -0.530  -0.619  -0.569  -0.492  -0.607  -0.543  -0.574  -0.659  -0.593
165   V        -0.136  -0.122  -0.062  -0.478  -0.472  -0.391  -0.409  -0.392  -0.318
166   S        -0.285  -0.298  -0.439  -0.286  -0.317  -0.485  -0.243  -0.264  -0.431
167   S         0.109   0.137   0.062  -0.149  -0.122  -0.217  -0.077  -0.061  -0.153
168   F         0.013  -0.046   0.014   0.237   0.184   0.281  -0.243  -0.303  -0.222
169   L         1.195   1.147   1.042   1.170   1.106   0.957   1.249   1.163   0.955
170   M        -0.530  -0.504  -0.542  -0.378  -0.325  -0.349  -0.574  -0.534  -0.564
171   G        -0.285  -0.149  -0.436  -0.171   0.037  -0.441  -0.243  -0.067  -0.428
172   I        -1.073  -1.088  -1.046  -1.202  -1.226  -1.124  -0.906  -0.911  -0.843
173   F         0.013   0.049   0.028  -0.072  -0.039  -0.052  -0.243  -0.193  -0.203
174   N         0.013  -0.046   0.014  -0.175  -0.229  -0.141  -0.243  -0.303  -0.222
175   S        -0.530  -0.579  -0.547  -0.652  -0.723  -0.651  -0.574  -0.624  -0.571
176   V         0.013   0.081   0.031  -0.251  -0.187  -0.189  -0.243  -0.159  -0.200
177   V         0.427   0.513   0.243   0.407   0.527   0.125   0.420   0.545   0.138
178   N        -0.136  -0.145  -0.068  -0.456  -0.477  -0.387  -0.409  -0.423  -0.326
179   L         0.109   0.011   0.046  -0.049  -0.206  -0.151  -0.077  -0.209  -0.173
180   S        -0.285  -0.280  -0.448  -0.145  -0.139  -0.425  -0.243  -0.242  -0.443
181   R         0.652   0.669   0.744   0.524   0.544   0.661   0.254   0.272   0.371
182   Y         1.195   1.086   1.022   1.571   1.444   1.366   1.249   1.059   0.917
183   P         2.012   2.044   2.124   2.164   2.204   2.339   2.243   2.291   2.428
184   K         2.012   2.044   2.124   2.061   2.113   2.236   2.243   2.291   2.428
185   S         2.012   2.044   2.124   1.787   1.839   1.959   2.243   2.291   2.428
186   G         0.652   0.674   0.752   0.409   0.432   0.555   0.254   0.282   0.386
187   I         1.195   1.086   1.022   1.150   1.001   0.904   1.249   1.059   0.917
188   D         2.012   2.044   2.124   2.068   2.112   2.242   2.243   2.291   2.428
189   I         1.195   1.147   1.042   1.150   1.087   0.937   1.249   1.163   0.955
190   F        -0.285  -0.411  -0.464   0.021  -0.198  -0.301  -0.243  -0.401  -0.461
191   V         0.652   0.701   0.758   0.280   0.353   0.438   0.254   0.336   0.399
192   Y         0.109   0.203   0.084  -0.031   0.101  -0.048  -0.077   0.065  -0.109
193   L        -0.136  -0.102  -0.037  -0.507  -0.459  -0.364  -0.409  -0.362  -0.282
194   T        -0.530  -0.610  -0.554  -0.688  -0.814  -0.729  -0.574  -0.648  -0.576
195   Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
196   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
197   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
198   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
199   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
200   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
201   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
202   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
203   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
204   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
205   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
206   D        -0.925  -0.900  -0.988  -0.821  -0.801  -0.862  -0.740  -0.714  -0.784
207   D        -1.468  -1.426  -1.408  -1.556  -1.504  -1.462  -1.071  -1.031  -0.983
208   S        -1.073  -1.075  -1.025  -1.125  -1.127  -1.038  -0.906  -0.901  -0.826
209   Q        -1.073  -1.054  -1.018  -1.034  -0.969  -0.934  -0.906  -0.880  -0.820
210   S        -0.925  -0.909  -0.970  -0.819  -0.776  -0.917  -0.740  -0.722  -0.766
211   K        -0.925  -0.990  -0.974  -0.629  -0.745  -0.729  -0.740  -0.806  -0.770
212   M        -1.862  -1.839  -1.765  -1.554  -1.517  -1.412  -1.237  -1.212  -1.120
213   M        -1.468  -1.355  -1.404  -1.261  -1.088  -1.168  -1.071  -0.964  -0.980
214   S        -1.468  -1.415  -1.396  -1.499  -1.420  -1.388  -1.071  -1.019  -0.974
215   S        -0.461  -0.528  -0.534  -0.491  -0.589  -0.566  -0.464  -0.547  -0.546
216   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
217   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
218   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
219   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
220   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
221   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
222   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
223   Q        -0.635  -0.654  -0.604  -0.791  -0.810  -0.711  -0.689  -0.705  -0.633
224   I        -0.002  -0.076  -0.005  -0.320  -0.427  -0.323  -0.238  -0.331  -0.241
225   S        -1.095  -1.077  -1.065  -1.026  -0.965  -0.962  -0.915  -0.895  -0.859
226   S        -0.461  -0.364  -0.486  -0.371  -0.199  -0.414  -0.464  -0.340  -0.488
227   L        -0.002  -0.060   0.013  -0.299  -0.375  -0.276  -0.238  -0.305  -0.217
228   I         0.109   0.117   0.091  -0.113  -0.082  -0.153  -0.077  -0.048  -0.106
229   P        -0.925  -0.985  -1.008  -0.647  -0.784  -0.813  -0.740  -0.802  -0.804
230   H        -1.073  -1.121  -1.059  -0.640  -0.736  -0.644  -0.906  -0.938  -0.855
231   C         0.109   0.102   0.080   0.241   0.247   0.186  -0.077  -0.074  -0.116
232   I         0.427   0.396   0.226   0.433   0.387   0.139   0.420   0.374   0.113
233   T        -0.679  -0.656  -0.599  -0.829  -0.788  -0.696  -0.740  -0.711  -0.632
234   S         0.013  -0.046   0.014  -0.110  -0.170  -0.083  -0.243  -0.303  -0.222
235   I        -0.530  -0.501  -0.558  -0.631  -0.599  -0.654  -0.574  -0.553  -0.585
236   T         0.013  -0.011   0.020  -0.290  -0.329  -0.271  -0.243  -0.261  -0.214
237   L        -0.136  -0.132  -0.057  -0.277  -0.282  -0.155  -0.409  -0.406  -0.310
238   A         2.012   2.044   2.124   2.049   2.083   2.223   2.243   2.291   2.428
239   L         2.012   2.044   2.124   1.908   1.955   2.081   2.243   2.291   2.428
240   A         0.013   0.078   0.042  -0.157  -0.080  -0.106  -0.243  -0.165  -0.187
241   D         2.012   2.044   2.124   2.068   2.112   2.242   2.243   2.291   2.428
242   A         0.652   0.674   0.752   0.285   0.305   0.424   0.254   0.282   0.386
243   G         1.195   1.287   1.054   1.287   1.404   1.101   1.249   1.392   0.978
244   I         1.195   1.147   1.042   1.135   1.071   0.910   1.249   1.163   0.955
245   E         1.195   1.086   1.022   1.313   1.169   1.075   1.249   1.059   0.917
246   L        -0.679  -0.642  -0.605  -0.694  -0.587  -0.554  -0.740  -0.693  -0.637
247   V        -0.679  -0.688  -0.605  -0.845  -0.857  -0.729  -0.740  -0.739  -0.635
248   D         2.012   2.044   2.124   2.068   2.112   2.242   2.243   2.291   2.428
249   M        -0.530  -0.540  -0.552  -0.648  -0.657  -0.647  -0.574  -0.576  -0.575
250   A         0.109   0.192   0.104   0.020   0.141   0.005  -0.077   0.051  -0.079
251   G        -0.679  -0.643  -0.603  -0.899  -0.853  -0.780  -0.740  -0.701  -0.634
252   A         0.109   0.056   0.066  -0.022  -0.098  -0.107  -0.077  -0.136  -0.137
253   G         2.012   2.044   2.124   2.013   2.057   2.187   2.243   2.291   2.428
254   E        -0.530  -0.570  -0.541  -0.505  -0.594  -0.553  -0.574  -0.617  -0.566
255   A        -0.530  -0.476  -0.542  -0.458  -0.419  -0.449  -0.574  -0.520  -0.569
256   N        -0.925  -1.003  -0.991  -0.745  -0.872  -0.857  -0.740  -0.819  -0.787
257   -         2.012   2.044   2.124   1.915   1.966   2.089   2.243   2.291   2.428
258   -        -0.748  -0.724  -0.647  -0.839  -0.806  -0.690  -0.802  -0.772  -0.676
259   -        -0.058  -0.029   0.000   0.047   0.088   0.118  -0.295  -0.255  -0.227
260   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
261   -        -0.058  -0.104  -0.037  -0.374  -0.446  -0.330  -0.295  -0.365  -0.281
262   -        -0.058  -0.015   0.002  -0.170  -0.107  -0.089  -0.295  -0.236  -0.224
263   -        -0.748  -0.724  -0.647  -0.799  -0.762  -0.650  -0.802  -0.772  -0.676
264   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
265   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
266   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
267   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
268   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
269   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
270   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
271   -        -0.058   0.046   0.003  -0.141   0.020  -0.056  -0.295  -0.143  -0.223
272   -         0.632   0.654   0.739   0.157   0.189   0.318   0.213   0.241   0.359
273   -         0.892   0.882   0.872   0.933   0.905   0.885   0.720   0.688   0.628
274   -        -0.748  -0.724  -0.647  -0.920  -0.891  -0.772  -0.802  -0.772  -0.676
275   -        -0.058  -0.029   0.000  -0.280  -0.237  -0.194  -0.295  -0.255  -0.227
276   -        -0.748  -0.724  -0.647  -0.896  -0.859  -0.748  -0.802  -0.772  -0.676
277   -        -0.748  -0.724  -0.647  -0.920  -0.910  -0.772  -0.802  -0.772  -0.676
278   -         0.892   0.882   0.872   0.891   0.863   0.829   0.720   0.688   0.628
279   -        -0.058  -0.104  -0.037  -0.123  -0.205  -0.117  -0.295  -0.365  -0.281
280   -        -0.058   0.046   0.003  -0.267  -0.069  -0.203  -0.295  -0.143  -0.223
281   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
282   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
283   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
284   -         0.892   0.840   0.859   0.691   0.596   0.621   0.720   0.609   0.604
285   G        -0.530  -0.548  -0.553  -0.500  -0.521  -0.528  -0.574  -0.582  -0.574
286   T        -0.679  -0.640  -0.606  -0.758  -0.683  -0.629  -0.740  -0.698  -0.637
287   V         0.109   0.056   0.066   0.046  -0.008   0.004  -0.077  -0.136  -0.137
288   V         0.427   0.384   0.214   0.523   0.435   0.194   0.420   0.349   0.094
289   S         0.821   0.789   0.793   0.509   0.447   0.443   0.586   0.511   0.471
290   F         0.821   0.747   0.791   0.991   0.868   0.925   0.586   0.428   0.467
291   I         0.013  -0.046   0.014  -0.077  -0.138  -0.064  -0.243  -0.303  -0.222
292   K        -1.073  -1.121  -1.059  -0.905  -0.956  -0.857  -0.906  -0.938  -0.855
293   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
294   N        -1.468  -1.474  -1.418  -1.249  -1.265  -1.174  -1.071  -1.071  -0.991
295   G        -0.530  -0.619  -0.569  -0.575  -0.694  -0.642  -0.574  -0.659  -0.593
296   E        -1.073  -1.054  -1.030  -0.765  -0.733  -0.679  -0.906  -0.881  -0.829
297   E         1.195   1.147   1.042   1.312   1.254   1.105   1.249   1.163   0.955
298   I         0.821   0.803   0.800   0.585   0.542   0.516   0.586   0.538   0.485
299   V         1.195   1.086   1.022   1.265   1.109   1.024   1.249   1.059   0.917
300   G         1.195   1.086   1.022   1.280   1.135   1.036   1.249   1.059   0.917
301   F        -0.530  -0.625  -0.549  -0.418  -0.555  -0.463  -0.574  -0.667  -0.575
302   W         2.012   2.044   2.124   2.338   2.389   2.515   2.243   2.291   2.428
303   K        -1.073  -1.046  -1.036  -1.007  -0.950  -0.973  -0.906  -0.872  -0.834
304   D         0.013  -0.046   0.014  -0.071  -0.146  -0.049  -0.243  -0.303  -0.222
305   D         0.109   0.215   0.069   0.075   0.233   0.010  -0.077   0.074  -0.137
306   G        -0.679  -0.636  -0.600  -0.730  -0.678  -0.608  -0.740  -0.695  -0.632
307   D        -0.635  -0.617  -0.593  -0.610  -0.579  -0.536  -0.689  -0.663  -0.620
308   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
309   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
310   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
311   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
312   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
313   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
314   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
315   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
316   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
317   -         0.892   0.882   0.872   0.737   0.713   0.679   0.720   0.688   0.628
318   -        -0.058  -0.104  -0.037  -0.237  -0.313  -0.246  -0.295  -0.365  -0.281
319   D        -0.925  -0.900  -0.988  -0.745  -0.719  -0.858  -0.740  -0.714  -0.784
320   E        -0.530  -0.504  -0.509  -0.718  -0.676  -0.672  -0.574  -0.535  -0.528
321   D        -0.285  -0.264  -0.435  -0.065  -0.025  -0.300  -0.243  -0.216  -0.426
322   L        -0.530  -0.413  -0.525  -0.455  -0.233  -0.458  -0.574  -0.431  -0.544
323   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
324   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
325   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
326   L        -1.073  -1.001  -1.023  -1.145  -1.033  -1.087  -0.906  -0.836  -0.824
327   E        -0.136  -0.126  -0.064  -0.192  -0.170  -0.080  -0.409  -0.396  -0.320
328   C         0.109   0.118   0.094   0.047   0.058   0.022  -0.077  -0.047  -0.094
329   L         0.427   0.429   0.234   0.452   0.465   0.182   0.420   0.420   0.124
330   D         0.013   0.041   0.040  -0.112  -0.076  -0.070  -0.243  -0.207  -0.192
331   R        -1.073  -0.977  -1.020  -0.949  -0.816  -0.862  -0.906  -0.812  -0.821
332   C         0.427   0.263   0.185   0.820   0.578   0.444   0.420   0.179   0.050
333   K        -0.530  -0.619  -0.569  -0.540  -0.666  -0.613  -0.574  -0.659  -0.593
334   E        -0.925  -0.923  -0.965  -0.749  -0.730  -0.826  -0.740  -0.737  -0.761
335   Q        -0.530  -0.548  -0.553  -0.228  -0.242  -0.263  -0.574  -0.582  -0.574
336   Y         0.013  -0.011   0.020  -0.114  -0.162  -0.101  -0.243  -0.261  -0.214
337   N        -0.530  -0.504  -0.542  -0.533  -0.467  -0.539  -0.574  -0.534  -0.564
338   R        -1.468  -1.441  -1.402  -1.339  -1.343  -1.249  -1.071  -1.043  -0.978
339   Y        -0.530  -0.548  -0.553  -0.512  -0.541  -0.534  -0.574  -0.582  -0.574
340   R         0.427   0.354   0.196   0.710   0.603   0.364   0.420   0.308   0.068
341   D        -1.468  -1.474  -1.405  -1.254  -1.266  -1.164  -1.071  -1.070  -0.981
342   L        -0.679  -0.637  -0.610  -0.858  -0.785  -0.741  -0.740  -0.690  -0.640
343   M         0.013   0.071   0.042  -0.068   0.011  -0.037  -0.243  -0.176  -0.188
344   I        -1.073  -1.038  -1.031  -0.954  -0.891  -0.872  -0.906  -0.867  -0.830
345   S        -1.073  -1.071  -1.025  -1.113  -1.105  -1.024  -0.906  -0.897  -0.826
346   C         0.109   0.039   0.052   0.378   0.269   0.284  -0.077  -0.177  -0.167
347   L         2.012   2.044   2.124   1.908   1.955   2.081   2.243   2.291   2.428
348   M        -1.095  -1.075  -1.046  -1.090  -1.058  -1.012  -0.915  -0.890  -0.841
349   N        -0.002   0.019   0.011  -0.157  -0.121  -0.168  -0.238  -0.226  -0.224
350   Q        -0.640  -0.636  -0.583  -0.530  -0.533  -0.463  -0.680  -0.673  -0.605
351   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
352   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
353   E        -0.640  -0.644  -0.616  -0.829  -0.844  -0.774  -0.680  -0.684  -0.642
354   T        -1.555  -1.530  -1.457  -1.323  -1.292  -1.179  -1.140  -1.112  -1.021
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P48240
Output conservation file - output/P48240
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
