1     M         0.959   0.977   1.029   1.138   1.162   1.223   1.006   1.028   1.100
2     S         0.959   0.977   1.029   1.005   1.032   1.106   1.006   1.028   1.100
3     T         0.006   0.108  -0.221   0.136   0.267  -0.211  -0.039   0.109  -0.407
4     D        -1.181  -1.110  -1.079  -1.241  -1.150  -1.076  -1.293  -1.209  -1.100
5     K         0.959   0.977   1.029   0.794   0.839   0.919   1.006   1.028   1.100
6     I         0.959   0.977   1.029   0.898   0.918   1.011   1.006   1.028   1.100
7     T         0.006   0.123  -0.219   0.136   0.286  -0.207  -0.039   0.130  -0.403
8     F         0.959   0.977   1.029   1.044   1.065   1.140   1.006   1.028   1.100
9     L         0.959   0.977   1.029   0.761   0.797   0.891   1.006   1.028   1.100
10    L        -0.876  -1.073  -1.068  -0.950  -1.235  -1.210  -0.875  -1.116  -1.084
11    N         0.959   0.977   1.029   1.069   1.091   1.162   1.006   1.028   1.100
12    W         0.959   0.977   1.029   1.209   1.232   1.285   1.006   1.028   1.100
13    Q        -1.181  -1.228  -1.086  -1.135  -1.219  -0.983  -1.293  -1.328  -1.108
14    P        -0.388  -0.245  -0.275  -0.557  -0.327  -0.378  -0.666  -0.428  -0.497
15    T        -0.388  -0.298  -0.292  -0.518  -0.367  -0.394  -0.666  -0.516  -0.527
16    P         0.959   0.977   1.029   1.014   1.040   1.113   1.006   1.028   1.100
17    Y         0.959   0.977   1.029   0.997   1.033   1.098   1.006   1.028   1.100
18    H         0.959   0.977   1.029   1.182   1.203   1.261   1.006   1.028   1.100
19    I        -1.670  -1.751  -1.647  -1.660  -1.840  -1.662  -1.502  -1.572  -1.392
20    P         0.959   0.977   1.029   1.014   1.040   1.113   1.006   1.028   1.100
21    I        -1.181  -1.176  -1.078  -1.340  -1.338  -1.188  -1.293  -1.255  -1.098
22    F        -0.388  -0.387  -0.310  -0.450  -0.452  -0.347  -0.666  -0.666  -0.558
23    L         0.006   0.123  -0.219  -0.120   0.043  -0.442  -0.039   0.130  -0.403
24    A         0.959   0.977   1.029   0.895   0.923   1.008   1.006   1.028   1.100
25    Q        -0.876  -0.731  -1.030  -0.598  -0.402  -0.851  -0.875  -0.680  -1.037
26    T        -1.670  -1.610  -1.629  -1.479  -1.416  -1.445  -1.502  -1.420  -1.375
27    K         0.006  -0.148  -0.241  -0.052  -0.244  -0.375  -0.039  -0.273  -0.441
28    G         0.959   0.977   1.029   0.863   0.884   0.980   1.006   1.028   1.100
29    Y        -0.388  -0.367  -0.307  -0.450  -0.417  -0.342  -0.666  -0.631  -0.553
30    F        -0.388  -0.402  -0.312  -0.428  -0.467  -0.345  -0.666  -0.691  -0.562
31    K         0.006  -0.148  -0.241  -0.093  -0.301  -0.467  -0.039  -0.273  -0.441
32    E        -0.876  -0.951  -1.049  -0.815  -0.925  -1.058  -0.875  -0.968  -1.061
33    Q        -0.507  -0.470  -0.320  -0.725  -0.672  -0.422  -0.875  -0.809  -0.574
34    G         0.006   0.083  -0.222   0.017   0.112  -0.292  -0.039   0.074  -0.409
35    L        -1.181  -1.014  -1.066  -1.405  -1.132  -1.191  -1.293  -1.066  -1.082
36    D        -0.876  -1.073  -1.068  -0.776  -1.077  -1.071  -0.875  -1.116  -1.084
37    I        -0.507  -0.448  -0.311  -0.773  -0.664  -0.439  -0.875  -0.771  -0.560
38    A         0.006   0.123  -0.219   0.035   0.189  -0.289  -0.039   0.130  -0.403
39    I         0.006  -0.072  -0.236  -0.011  -0.132  -0.423  -0.039  -0.154  -0.433
40    L         0.959   0.977   1.029   0.761   0.797   0.891   1.006   1.028   1.100
41    E         0.959   0.977   1.029   0.872   0.901   0.988   1.006   1.028   1.100
42    P         0.959   0.977   1.029   1.014   1.040   1.113   1.006   1.028   1.100
43    T        -1.181  -1.221  -1.085  -1.159  -1.219  -0.997  -1.293  -1.318  -1.106
44    N         0.006  -0.072  -0.236   0.192   0.077  -0.216  -0.039  -0.154  -0.433
45    P         0.959   0.977   1.029   1.014   1.040   1.113   1.006   1.028   1.100
46    S         0.959   0.977   1.029   1.005   1.032   1.106   1.006   1.028   1.100
47    D         0.959   0.977   1.029   0.923   0.950   1.033   1.006   1.028   1.100
48    V         0.959   0.977   1.029   0.988   1.017   1.091   1.006   1.028   1.100
49    T         0.959   0.977   1.029   0.997   1.021   1.098   1.006   1.028   1.100
50    E         0.006  -0.148  -0.241  -0.010  -0.233  -0.394  -0.039  -0.273  -0.441
51    L         0.006  -0.072  -0.236  -0.120  -0.222  -0.473  -0.039  -0.154  -0.433
52    I         0.006   0.083  -0.222   0.034   0.131  -0.299  -0.039   0.074  -0.409
53    G         0.959   0.977   1.029   0.863   0.884   0.980   1.006   1.028   1.100
54    S         0.959   0.977   1.029   1.005   1.032   1.106   1.006   1.028   1.100
55    G         0.959   0.977   1.029   0.863   0.884   0.980   1.006   1.028   1.100
56    K         0.959   0.977   1.029   0.794   0.839   0.919   1.006   1.028   1.100
57    V         0.006   0.123  -0.219   0.106   0.263  -0.258  -0.039   0.130  -0.403
58    D         0.959   0.977   1.029   0.923   0.950   1.033   1.006   1.028   1.100
59    M         0.006  -0.072  -0.236   0.229   0.110  -0.228  -0.039  -0.154  -0.433
60    G         0.959   0.977   1.029   0.863   0.884   0.980   1.006   1.028   1.100
61    L         0.006  -0.072  -0.236  -0.090  -0.184  -0.406  -0.039  -0.154  -0.433
62    K         0.959   0.977   1.029   0.794   0.839   0.919   1.006   1.028   1.100
63    A         0.959   0.977   1.029   0.895   0.923   1.008   1.006   1.028   1.100
64    M         0.959   0.977   1.029   1.138   1.162   1.223   1.006   1.028   1.100
65    I        -0.388  -0.291  -0.287  -0.566  -0.415  -0.410  -0.666  -0.503  -0.519
66    H         0.959   0.977   1.029   1.182   1.203   1.261   1.006   1.028   1.100
67    T         0.959   0.977   1.029   0.997   1.021   1.098   1.006   1.028   1.100
68    L         0.959   0.977   1.029   0.761   0.797   0.891   1.006   1.028   1.100
69    A         0.959   0.977   1.029   0.895   0.923   1.008   1.006   1.028   1.100
70    A         0.959   0.977   1.029   0.895   0.923   1.008   1.006   1.028   1.100
71    K         0.959   0.977   1.029   0.794   0.839   0.919   1.006   1.028   1.100
72    A         0.959   0.977   1.029   0.895   0.923   1.008   1.006   1.028   1.100
73    R         0.959   0.977   1.029   1.072   1.090   1.165   1.006   1.028   1.100
74    G         0.006  -0.072  -0.236   0.017  -0.091  -0.315  -0.039  -0.154  -0.433
75    F        -1.181  -1.028  -1.063  -1.224  -0.971  -1.066  -1.293  -1.076  -1.079
76    P         0.006   0.108  -0.221   0.136   0.273  -0.231  -0.039   0.109  -0.407
77    V         0.959   0.977   1.029   0.988   1.017   1.091   1.006   1.028   1.100
78    T         0.006  -0.072  -0.236   0.088  -0.029  -0.342  -0.039  -0.154  -0.433
79    S         0.959   0.977   1.029   1.005   1.032   1.106   1.006   1.028   1.100
80    V        -1.181  -1.194  -1.075  -1.260  -1.263  -1.064  -1.293  -1.271  -1.094
81    A        -0.388  -0.254  -0.278  -0.641  -0.420  -0.467  -0.666  -0.442  -0.502
82    S         0.959   0.977   1.029   1.005   1.032   1.106   1.006   1.028   1.100
83    L         0.959   0.977   1.029   0.761   0.797   0.891   1.006   1.028   1.100
84    L         0.959   0.977   1.029   0.761   0.797   0.891   1.006   1.028   1.100
85    D         0.006  -0.148  -0.241   0.076  -0.136  -0.275  -0.039  -0.273  -0.441
86    E         0.959   0.977   1.029   0.872   0.901   0.988   1.006   1.028   1.100
87    P         0.959   0.977   1.029   1.014   1.040   1.113   1.006   1.028   1.100
88    F         0.959   0.977   1.029   1.044   1.065   1.140   1.006   1.028   1.100
89    T         0.959   0.977   1.029   0.997   1.021   1.098   1.006   1.028   1.100
90    G         0.959   0.977   1.029   0.863   0.884   0.980   1.006   1.028   1.100
91    V        -0.876  -0.951  -1.049  -0.783  -0.926  -1.120  -0.875  -0.968  -1.061
92    L        -1.670  -1.766  -1.648  -1.672  -1.825  -1.582  -1.502  -1.586  -1.393
93    Y         0.006  -0.148  -0.241   0.134  -0.076  -0.250  -0.039  -0.273  -0.441
94    L         0.959   0.977   1.029   0.761   0.797   0.891   1.006   1.028   1.100
95    K        -0.507  -0.458  -0.315  -0.936  -0.841  -0.599  -0.875  -0.788  -0.567
96    G         0.006  -0.072  -0.236  -0.024  -0.139  -0.403  -0.039  -0.154  -0.433
97    S         0.006  -0.148  -0.241   0.157  -0.056  -0.212  -0.039  -0.273  -0.441
98    G         0.959   0.977   1.029   0.863   0.884   0.980   1.006   1.028   1.100
99    I         0.959   0.977   1.029   0.898   0.918   1.011   1.006   1.028   1.100
100   T         0.959   0.977   1.029   1.002   1.027   1.102   1.006   1.028   1.100
101   E        -2.343  -2.297  -2.095  -2.088  -2.027  -1.743  -1.920  -1.853  -1.574
102   D         0.959   0.977   1.029   0.923   0.950   1.033   1.006   1.028   1.100
103   F         0.959   0.977   1.029   1.044   1.065   1.140   1.006   1.028   1.100
104   Q        -2.343  -2.317  -2.094  -2.064  -2.075  -1.736  -1.920  -1.867  -1.573
105   S         0.006  -0.148  -0.241   0.128  -0.097  -0.276  -0.039  -0.273  -0.441
106   L         0.006  -0.148  -0.241  -0.120  -0.337  -0.482  -0.039  -0.273  -0.441
107   K         0.959   0.977   1.029   0.794   0.839   0.919   1.006   1.028   1.100
108   G         0.959   0.977   1.029   0.863   0.884   0.980   1.006   1.028   1.100
109   K         0.959   0.977   1.029   0.794   0.839   0.919   1.006   1.028   1.100
110   K        -0.507  -0.444  -0.310  -0.785  -0.639  -0.435  -0.875  -0.763  -0.557
111   I         0.959   0.977   1.029   0.898   0.918   1.011   1.006   1.028   1.100
112   G         0.959   0.977   1.029   0.863   0.884   0.980   1.006   1.028   1.100
113   Y         0.959   0.977   1.029   0.997   1.033   1.098   1.006   1.028   1.100
114   V         0.959   0.977   1.029   0.988   1.017   1.091   1.006   1.028   1.100
115   G         0.959   0.977   1.029   0.863   0.884   0.980   1.006   1.028   1.100
116   E         0.959   0.977   1.029   0.872   0.901   0.988   1.006   1.028   1.100
117   F         0.959   0.977   1.029   1.044   1.065   1.140   1.006   1.028   1.100
118   G         0.959   0.977   1.029   0.863   0.884   0.980   1.006   1.028   1.100
119   K         0.959   0.977   1.029   0.794   0.839   0.919   1.006   1.028   1.100
120   I         0.959   0.977   1.029   0.898   0.918   1.011   1.006   1.028   1.100
121   Q         0.959   0.977   1.029   1.078   1.104   1.170   1.006   1.028   1.100
122   I        -0.876  -0.951  -1.049  -0.850  -0.998  -1.146  -0.875  -0.968  -1.061
123   D         0.959   0.977   1.029   0.923   0.950   1.033   1.006   1.028   1.100
124   E         0.006  -0.148  -0.241  -0.005  -0.225  -0.382  -0.039  -0.273  -0.441
125   L         0.959   0.977   1.029   0.761   0.797   0.891   1.006   1.028   1.100
126   T         0.006  -0.148  -0.241   0.159  -0.051  -0.195  -0.039  -0.273  -0.441
127   K        -0.388  -0.452  -0.319  -0.653  -0.746  -0.519  -0.666  -0.777  -0.573
128   H         0.006  -0.148  -0.241   0.279   0.039  -0.190  -0.039  -0.273  -0.441
129   Y         0.006  -0.148  -0.241   0.144  -0.063  -0.229  -0.039  -0.273  -0.441
130   G         0.959   0.977   1.029   0.863   0.884   0.980   1.006   1.028   1.100
131   M        -0.388  -0.452  -0.319  -0.446  -0.623  -0.437  -0.666  -0.777  -0.573
132   K        -1.181  -1.199  -1.077  -1.296  -1.280  -1.117  -1.293  -1.278  -1.096
133   P         0.959   0.977   1.029   1.014   1.040   1.113   1.006   1.028   1.100
134   E        -2.343  -2.297  -2.095  -2.250  -2.192  -1.890  -1.920  -1.853  -1.574
135   D         0.959   0.977   1.029   0.923   0.950   1.033   1.006   1.028   1.100
136   Y         0.959   0.977   1.029   0.997   1.033   1.098   1.006   1.028   1.100
137   T        -0.876  -0.731  -1.030  -0.727  -0.525  -0.995  -0.875  -0.680  -1.037
138   A         0.006   0.123  -0.219   0.036   0.190  -0.285  -0.039   0.130  -0.403
139   V         0.006  -0.148  -0.241   0.106  -0.122  -0.300  -0.039  -0.273  -0.441
140   R         0.959   0.977   1.029   1.072   1.090   1.165   1.006   1.028   1.100
141   C         0.959   0.977   1.029   1.122   1.148   1.208   1.006   1.028   1.100
142   G         0.959   0.977   1.029   0.863   0.884   0.980   1.006   1.028   1.100
143   M         0.959   0.977   1.029   1.138   1.162   1.223   1.006   1.028   1.100
144   N         0.959   0.977   1.029   1.069   1.091   1.162   1.006   1.028   1.100
145   V         0.006  -0.148  -0.241   0.106  -0.122  -0.300  -0.039  -0.273  -0.441
146   A         0.006  -0.072  -0.236   0.035  -0.068  -0.318  -0.039  -0.154  -0.433
147   K         0.006  -0.148  -0.241  -0.064  -0.259  -0.402  -0.039  -0.273  -0.441
148   Y        -0.388  -0.452  -0.319  -0.518  -0.655  -0.453  -0.666  -0.777  -0.573
149   I         0.959   0.977   1.029   0.898   0.918   1.011   1.006   1.028   1.100
150   I         0.006   0.083  -0.222  -0.011   0.091  -0.395  -0.039   0.074  -0.409
151   E        -0.876  -1.073  -1.068  -0.847  -1.138  -1.146  -0.875  -1.116  -1.084
152   D         0.006   0.172  -0.212  -0.013   0.197  -0.338  -0.039   0.198  -0.393
153   K        -1.181  -1.145  -1.087  -1.429  -1.378  -1.229  -1.293  -1.247  -1.108
154   I         0.959   0.977   1.029   0.898   0.918   1.011   1.006   1.028   1.100
155   D         0.959   0.977   1.029   0.923   0.950   1.033   1.006   1.028   1.100
156   A        -0.876  -0.951  -1.049  -0.795  -0.930  -1.046  -0.875  -0.968  -1.061
157   G         0.959   0.977   1.029   0.863   0.884   0.980   1.006   1.028   1.100
158   I         0.006   0.108  -0.221   0.034   0.162  -0.297  -0.039   0.109  -0.407
159   G         0.959   0.977   1.029   0.863   0.884   0.980   1.006   1.028   1.100
160   I         0.006  -0.072  -0.236  -0.011  -0.132  -0.423  -0.039  -0.154  -0.433
161   E         0.959   0.977   1.029   0.872   0.901   0.988   1.006   1.028   1.100
162   C         0.006  -0.072  -0.236   0.272   0.166  -0.113  -0.039  -0.154  -0.433
163   M        -1.181  -1.172  -1.077  -1.124  -1.095  -0.981  -1.293  -1.249  -1.096
164   Q         0.959   0.977   1.029   1.078   1.104   1.170   1.006   1.028   1.100
165   Q         0.006  -0.072  -0.236   0.242   0.140  -0.117  -0.039  -0.154  -0.433
166   V         0.959   0.977   1.029   0.988   1.017   1.091   1.006   1.028   1.100
167   E         0.006   0.108  -0.221   0.027   0.161  -0.280  -0.039   0.109  -0.407
168   L         0.959   0.977   1.029   0.761   0.797   0.891   1.006   1.028   1.100
169   E         0.959   0.977   1.029   0.872   0.901   0.988   1.006   1.028   1.100
170   E        -0.876  -0.918  -1.045  -0.815  -0.881  -1.052  -0.875  -0.930  -1.055
171   Y        -1.181  -1.145  -1.087  -1.095  -1.024  -0.951  -1.293  -1.247  -1.108
172   L         0.006  -0.148  -0.241  -0.073  -0.268  -0.378  -0.039  -0.273  -0.441
173   A        -1.854  -1.828  -1.651  -1.950  -1.901  -1.590  -1.711  -1.657  -1.396
174   K        -1.365  -1.277  -1.105  -1.658  -1.471  -1.224  -1.502  -1.374  -1.128
175   Q         0.006   0.108  -0.221   0.175   0.318  -0.232  -0.039   0.109  -0.407
176   G         0.959   0.977   1.029   0.863   0.884   0.980   1.006   1.028   1.100
177   R         0.006   0.083  -0.222   0.170   0.271  -0.239  -0.039   0.074  -0.409
178   P        -0.507  -0.472  -0.320  -0.735  -0.682  -0.429  -0.875  -0.813  -0.575
179   A        -2.832  -2.724  -2.458  -2.648  -2.490  -2.114  -2.129  -2.013  -1.691
180   S        -1.670  -1.610  -1.629  -1.523  -1.443  -1.510  -1.502  -1.420  -1.375
181   D         0.959   0.977   1.029   0.923   0.950   1.033   1.006   1.028   1.100
182   A        -0.388  -0.452  -0.319  -0.568  -0.687  -0.463  -0.666  -0.777  -0.573
183   K        -0.388  -0.452  -0.319  -0.619  -0.701  -0.473  -0.666  -0.777  -0.573
184   M         0.959   0.977   1.029   1.138   1.162   1.223   1.006   1.028   1.100
185   L         0.959   0.977   1.029   0.761   0.797   0.891   1.006   1.028   1.100
186   R         0.959   0.977   1.029   1.072   1.090   1.165   1.006   1.028   1.100
187   I         0.959   0.977   1.029   0.898   0.918   1.011   1.006   1.028   1.100
188   D         0.959   0.977   1.029   0.923   0.950   1.033   1.006   1.028   1.100
189   K        -1.181  -1.258  -1.089  -1.407  -1.486  -1.198  -1.293  -1.356  -1.110
190   L         0.959   0.977   1.029   0.761   0.797   0.891   1.006   1.028   1.100
191   A         0.959   0.977   1.029   0.895   0.923   1.008   1.006   1.028   1.100
192   C        -1.181  -1.199  -1.077  -1.199  -1.212  -1.004  -1.293  -1.278  -1.096
193   L         0.959   0.977   1.029   0.761   0.797   0.891   1.006   1.028   1.100
194   G         0.959   0.977   1.029   0.863   0.884   0.980   1.006   1.028   1.100
195   C         0.959   0.977   1.029   1.122   1.148   1.208   1.006   1.028   1.100
196   C         0.959   0.977   1.029   1.122   1.148   1.208   1.006   1.028   1.100
197   C         0.959   0.977   1.029   1.122   1.148   1.208   1.006   1.028   1.100
198   F         0.959   0.977   1.029   1.044   1.065   1.140   1.006   1.028   1.100
199   C         0.959   0.977   1.029   1.122   1.148   1.208   1.006   1.028   1.100
200   T         0.006  -0.072  -0.236   0.136   0.028  -0.238  -0.039  -0.154  -0.433
201   V         0.006   0.172  -0.212   0.034   0.240  -0.283  -0.039   0.198  -0.393
202   L         0.959   0.977   1.029   0.761   0.797   0.891   1.006   1.028   1.100
203   Y         0.959   0.977   1.029   0.997   1.033   1.098   1.006   1.028   1.100
204   I         0.959   0.977   1.029   0.898   0.918   1.011   1.006   1.028   1.100
205   C        -1.181  -1.142  -1.069  -1.237  -1.184  -1.064  -1.293  -1.209  -1.085
206   N         0.006  -0.148  -0.241   0.242   0.033  -0.113  -0.039  -0.273  -0.441
207   D         0.006  -0.072  -0.236   0.036  -0.074  -0.354  -0.039  -0.154  -0.433
208   E        -1.181  -1.176  -1.078  -1.407  -1.366  -1.210  -1.293  -1.255  -1.098
209   F         0.959   0.977   1.029   1.044   1.065   1.140   1.006   1.028   1.100
210   L        -0.507  -0.444  -0.310  -0.940  -0.811  -0.580  -0.875  -0.763  -0.557
211   K        -1.181  -1.142  -1.069  -1.384  -1.277  -1.171  -1.293  -1.209  -1.085
212   K        -1.854  -1.801  -1.648  -1.998  -1.899  -1.642  -1.711  -1.630  -1.393
213   N         0.006  -0.148  -0.241   0.242   0.033  -0.113  -0.039  -0.273  -0.441
214   P         0.006   0.083  -0.222   0.153   0.255  -0.199  -0.039   0.074  -0.409
215   E        -1.854  -1.710  -1.648  -1.875  -1.657  -1.525  -1.711  -1.539  -1.394
216   K         0.006   0.083  -0.222  -0.088   0.035  -0.423  -0.039   0.074  -0.409
217   V         0.006  -0.148  -0.241   0.106  -0.122  -0.300  -0.039  -0.273  -0.441
218   R        -0.388  -0.349  -0.303  -0.621  -0.551  -0.464  -0.666  -0.601  -0.546
219   K        -0.388  -0.452  -0.319  -0.706  -0.816  -0.590  -0.666  -0.777  -0.573
220   F         0.959   0.977   1.029   1.044   1.065   1.140   1.006   1.028   1.100
221   L         0.006  -0.072  -0.236  -0.070  -0.159  -0.363  -0.039  -0.154  -0.433
222   K        -1.181  -1.130  -1.087  -1.291  -1.203  -1.075  -1.293  -1.233  -1.108
223   A         0.959   0.977   1.029   0.895   0.923   1.008   1.006   1.028   1.100
224   I        -0.876  -0.854  -1.039  -0.793  -0.776  -1.030  -0.875  -0.841  -1.049
225   K         0.006  -0.148  -0.241  -0.029  -0.210  -0.325  -0.039  -0.273  -0.441
226   K        -1.181  -1.221  -1.081  -1.310  -1.346  -1.110  -1.293  -1.307  -1.101
227   A         0.959   0.977   1.029   0.895   0.923   1.008   1.006   1.028   1.100
228   T         0.959   0.977   1.029   0.997   1.021   1.098   1.006   1.028   1.100
229   D         0.006  -0.148  -0.241   0.015  -0.221  -0.412  -0.039  -0.273  -0.441
230   Y        -1.670  -1.751  -1.647  -1.540  -1.676  -1.561  -1.502  -1.572  -1.392
231   V        -1.181  -1.110  -1.079  -1.141  -1.049  -0.987  -1.293  -1.209  -1.100
232   L         0.959   0.977   1.029   0.761   0.797   0.891   1.006   1.028   1.100
233   A        -0.876  -0.931  -1.047  -0.823  -0.930  -1.092  -0.875  -0.945  -1.058
234   D        -1.181  -1.172  -1.077  -1.123  -1.107  -0.941  -1.293  -1.249  -1.096
235   P         0.959   0.977   1.029   1.014   1.040   1.113   1.006   1.028   1.100
236   V        -2.343  -2.234  -2.083  -2.239  -2.073  -1.879  -1.920  -1.795  -1.565
237   K        -1.670  -1.564  -1.620  -1.516  -1.359  -1.528  -1.502  -1.374  -1.367
238   A         0.006  -0.148  -0.241   0.033  -0.183  -0.330  -0.039  -0.273  -0.441
239   W         0.006  -0.148  -0.241   0.343   0.119  -0.084  -0.039  -0.273  -0.441
240   K        -0.876  -0.718  -1.028  -0.950  -0.707  -1.182  -0.875  -0.663  -1.035
241   E         0.006   0.108  -0.221  -0.005   0.134  -0.346  -0.039   0.109  -0.407
242   Y         0.959   0.977   1.029   0.997   1.033   1.098   1.006   1.028   1.100
243   I        -1.854  -1.740  -1.644  -1.880  -1.733  -1.555  -1.711  -1.579  -1.390
244   D        -0.876  -0.951  -1.049  -0.702  -0.805  -0.913  -0.875  -0.968  -1.061
245   F         0.959   0.977   1.029   1.044   1.065   1.140   1.006   1.028   1.100
246   K         0.959   0.977   1.029   0.794   0.839   0.919   1.006   1.028   1.100
247   P         0.006  -0.148  -0.241   0.166  -0.049  -0.204  -0.039  -0.273  -0.441
248   Q        -1.670  -1.766  -1.648  -1.428  -1.615  -1.459  -1.502  -1.586  -1.393
249   L        -0.388  -0.254  -0.278  -0.446  -0.198  -0.320  -0.666  -0.442  -0.502
250   N        -1.854  -1.705  -1.648  -1.777  -1.603  -1.459  -1.711  -1.535  -1.394
251   N        -1.854  -1.702  -1.642  -1.759  -1.566  -1.440  -1.711  -1.547  -1.389
252   D        -1.181  -1.025  -1.066  -1.328  -1.087  -1.115  -1.293  -1.079  -1.082
253   L         0.959   0.977   1.029   0.761   0.797   0.891   1.006   1.028   1.100
254   S        -1.181  -1.199  -1.077  -1.071  -1.066  -0.891  -1.293  -1.278  -1.096
255   Y        -1.854  -1.705  -1.648  -1.712  -1.488  -1.405  -1.711  -1.535  -1.394
256   K         0.006  -0.148  -0.241  -0.093  -0.301  -0.467  -0.039  -0.273  -0.441
257   Q        -1.670  -1.599  -1.628  -1.435  -1.349  -1.432  -1.502  -1.409  -1.374
258   Y         0.006   0.172  -0.212   0.181   0.390  -0.162  -0.039   0.198  -0.393
259   Q        -0.507  -0.451  -0.313  -0.725  -0.649  -0.417  -0.875  -0.775  -0.562
260   R         0.959   0.977   1.029   1.072   1.090   1.165   1.006   1.028   1.100
261   C         0.006  -0.072  -0.236   0.259   0.152  -0.140  -0.039  -0.154  -0.433
262   Y        -0.507  -0.471  -0.320  -0.660  -0.601  -0.361  -0.875  -0.811  -0.574
263   A         0.959   0.977   1.029   0.895   0.923   1.008   1.006   1.028   1.100
264   Y         0.959   0.977   1.029   0.997   1.033   1.098   1.006   1.028   1.100
265   F         0.959   0.977   1.029   1.044   1.065   1.140   1.006   1.028   1.100
266   S         0.959   0.977   1.029   1.005   1.032   1.106   1.006   1.028   1.100
267   S        -1.854  -1.820  -1.651  -1.804  -1.736  -1.474  -1.711  -1.648  -1.396
268   S        -0.388  -0.452  -0.319  -0.497  -0.639  -0.430  -0.666  -0.777  -0.573
269   L         0.006  -0.148  -0.241  -0.120  -0.337  -0.482  -0.039  -0.273  -0.441
270   Y        -0.876  -1.073  -1.068  -0.741  -1.038  -1.088  -0.875  -1.116  -1.084
271   N         0.959   0.977   1.029   1.069   1.091   1.162   1.006   1.028   1.100
272   V         0.959   0.977   1.029   0.988   1.017   1.091   1.006   1.028   1.100
273   H        -0.876  -1.073  -1.068  -0.542  -0.861  -0.924  -0.875  -1.116  -1.084
274   R         0.959   0.977   1.029   1.072   1.090   1.165   1.006   1.028   1.100
275   D         0.959   0.977   1.029   0.923   0.950   1.033   1.006   1.028   1.100
276   W         0.959   0.977   1.029   1.209   1.232   1.285   1.006   1.028   1.100
277   K        -1.854  -1.898  -1.658  -1.821  -1.848  -1.492  -1.711  -1.713  -1.402
278   K         0.959   0.977   1.029   0.794   0.839   0.919   1.006   1.028   1.100
279   V         0.959   0.977   1.029   0.988   1.017   1.091   1.006   1.028   1.100
280   T         0.006   0.083  -0.222   0.149   0.247  -0.186  -0.039   0.074  -0.409
281   G        -1.854  -1.769  -1.646  -1.898  -1.764  -1.594  -1.711  -1.602  -1.392
282   Y         0.959   0.977   1.029   0.997   1.033   1.098   1.006   1.028   1.100
283   G         0.006  -0.148  -0.241   0.003  -0.217  -0.351  -0.039  -0.273  -0.441
284   K         0.006  -0.072  -0.236  -0.051  -0.133  -0.365  -0.039  -0.154  -0.433
285   R         0.959   0.977   1.029   1.072   1.090   1.165   1.006   1.028   1.100
286   L         0.959   0.977   1.029   0.761   0.797   0.891   1.006   1.028   1.100
287   A        -1.854  -1.670  -1.647  -1.987  -1.729  -1.661  -1.711  -1.510  -1.393
288   I         0.006  -0.072  -0.236   0.034  -0.078  -0.323  -0.039  -0.154  -0.433
289   L         0.006  -0.148  -0.241  -0.120  -0.337  -0.482  -0.039  -0.273  -0.441
290   P         0.006  -0.072  -0.236   0.153   0.047  -0.225  -0.039  -0.154  -0.433
291   P        -1.670  -1.658  -1.634  -1.459  -1.450  -1.437  -1.502  -1.476  -1.380
292   D         0.006   0.083  -0.222   0.076   0.177  -0.244  -0.039   0.074  -0.409
293   Y        -0.507  -0.448  -0.311  -0.660  -0.555  -0.343  -0.875  -0.771  -0.560
294   V        -1.854  -1.801  -1.647  -1.925  -1.840  -1.609  -1.711  -1.628  -1.393
295   S        -0.507  -0.444  -0.310  -0.676  -0.567  -0.357  -0.875  -0.763  -0.557
296   N         0.959   0.977   1.029   1.069   1.091   1.162   1.006   1.028   1.100
297   Y         0.006  -0.148  -0.241   0.159  -0.039  -0.195  -0.039  -0.273  -0.441
298   T         0.006   0.123  -0.219   0.136   0.286  -0.207  -0.039   0.130  -0.403
299   N         0.959   0.977   1.029   1.069   1.091   1.162   1.006   1.028   1.100
300   E         0.006  -0.148  -0.241  -0.017  -0.244  -0.409  -0.039  -0.273  -0.441
301   Y         0.006  -0.072  -0.236   0.144   0.048  -0.221  -0.039  -0.154  -0.433
302   L         0.959   0.977   1.029   0.761   0.797   0.891   1.006   1.028   1.100
303   S        -0.876  -1.073  -1.068  -0.704  -1.008  -1.029  -0.875  -1.116  -1.084
304   W         0.959   0.977   1.029   1.209   1.232   1.285   1.006   1.028   1.100
305   P        -1.181  -1.227  -1.086  -1.270  -1.361  -1.141  -1.293  -1.326  -1.108
306   E        -0.388  -0.452  -0.319  -0.695  -0.844  -0.621  -0.666  -0.777  -0.573
307   P        -0.876  -1.073  -1.068  -0.676  -0.977  -0.987  -0.875  -1.116  -1.084
308   E        -1.854  -1.676  -1.647  -1.934  -1.639  -1.595  -1.711  -1.514  -1.393
309   E         0.006  -0.148  -0.241  -0.005  -0.225  -0.382  -0.039  -0.273  -0.441
310   V        -0.876  -1.073  -1.068  -0.731  -1.039  -1.060  -0.875  -1.116  -1.084
311   S        -1.854  -1.828  -1.651  -1.921  -1.897  -1.626  -1.711  -1.657  -1.396
312   D         0.959   0.977   1.029   0.923   0.950   1.033   1.006   1.028   1.100
313   P         0.959   0.977   1.029   1.014   1.040   1.113   1.006   1.028   1.100
314   L        -1.854  -1.839  -1.651  -1.917  -1.845  -1.565  -1.711  -1.664  -1.397
315   E        -1.670  -1.432  -1.612  -1.720  -1.362  -1.664  -1.502  -1.225  -1.359
316   A        -0.876  -1.073  -1.068  -0.861  -1.177  -1.198  -0.875  -1.116  -1.084
317   Q         0.959   0.977   1.029   1.078   1.104   1.170   1.006   1.028   1.100
318   R        -2.343  -2.326  -2.097  -2.173  -2.211  -1.861  -1.920  -1.874  -1.575
319   L        -0.876  -1.073  -1.068  -0.930  -1.216  -1.174  -0.875  -1.116  -1.084
320   M        -0.388  -0.406  -0.314  -0.387  -0.449  -0.340  -0.666  -0.699  -0.564
321   A        -1.854  -1.807  -1.648  -2.075  -1.973  -1.724  -1.711  -1.635  -1.394
322   I        -1.854  -1.676  -1.647  -2.065  -1.783  -1.715  -1.711  -1.514  -1.393
323   H        -0.876  -1.073  -1.068  -0.594  -0.935  -1.021  -0.875  -1.116  -1.084
324   Q         0.959   0.977   1.029   1.078   1.104   1.170   1.006   1.028   1.100
325   E        -0.876  -1.073  -1.068  -0.884  -1.192  -1.215  -0.875  -1.116  -1.084
326   K        -1.670  -1.546  -1.623  -1.648  -1.456  -1.590  -1.502  -1.356  -1.369
327   C        -0.876  -1.073  -1.068  -0.600  -0.919  -0.965  -0.875  -1.116  -1.084
328   R        -1.181  -1.148  -1.073  -1.341  -1.281  -1.149  -1.293  -1.217  -1.090
329   Q        -2.343  -2.234  -2.083  -2.022  -1.860  -1.674  -1.920  -1.795  -1.565
330   E        -1.670  -1.597  -1.629  -1.420  -1.351  -1.440  -1.502  -1.417  -1.375
331   G         0.959   0.977   1.029   0.863   0.884   0.980   1.006   1.028   1.100
332   T         0.006   0.172  -0.212   0.002   0.208  -0.307  -0.039   0.198  -0.393
333   F        -1.181  -1.221  -1.081  -1.149  -1.197  -0.999  -1.293  -1.307  -1.101
334   K        -1.854  -1.792  -1.646  -1.778  -1.656  -1.418  -1.711  -1.621  -1.392
335   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
336   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
337   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
338   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
339   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
340   R         0.959   0.977   1.029   1.072   1.090   1.165   1.006   1.028   1.100
341   L        -0.876  -0.931  -1.047  -0.926  -1.003  -1.139  -0.875  -0.945  -1.058
342   A        -1.854  -1.794  -1.647  -1.876  -1.765  -1.549  -1.711  -1.620  -1.393
343   L        -0.876  -0.918  -1.045  -0.958  -1.034  -1.191  -0.875  -0.930  -1.055
344   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
345   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
346   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
347   A        -1.670  -1.631  -1.628  -1.668  -1.648  -1.638  -1.502  -1.450  -1.374
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P47183
Output conservation file - output/P47183
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
