1     M         1.112   1.112   1.112   1.346   1.346   1.346   1.112   1.112   1.112
2     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     N        -0.897  -0.897  -0.897  -0.746  -0.746  -0.746  -0.897  -0.897  -0.897
5     T        -0.897  -0.897  -0.897  -1.000  -1.000  -1.000  -0.897  -0.897  -0.897
6     D        -0.897  -0.897  -0.897  -1.000  -1.000  -1.000  -0.897  -0.897  -0.897
7     S        -0.897  -0.897  -0.897  -0.978  -0.978  -0.978  -0.897  -0.897  -0.897
8     H        -0.897  -0.897  -0.897  -0.815  -0.815  -0.815  -0.897  -0.897  -0.897
9     N        -0.897  -0.897  -0.897  -1.022  -1.022  -1.022  -0.897  -0.897  -0.897
10    L        -0.897  -0.897  -0.897  -0.993  -0.993  -0.993  -0.897  -0.897  -0.897
11    S        -0.897  -0.897  -0.897  -1.074  -1.074  -1.074  -0.897  -0.897  -0.897
12    E        -0.897  -0.897  -0.897  -0.885  -0.885  -0.885  -0.897  -0.897  -0.897
13    P        -0.897  -0.897  -0.897  -0.787  -0.787  -0.787  -0.897  -0.897  -0.897
14    Y        -0.897  -0.897  -0.897  -0.928  -0.928  -0.928  -0.897  -0.897  -0.897
15    N        -0.897  -0.897  -0.897  -1.015  -1.015  -1.015  -0.897  -0.897  -0.897
16    I        -0.897  -0.897  -0.897  -0.964  -0.964  -0.964  -0.897  -0.897  -0.897
17    G        -0.897  -0.897  -0.897  -0.935  -0.935  -0.935  -0.897  -0.897  -0.897
18    G         1.112   1.112   1.112   1.048   1.048   1.048   1.112   1.112   1.112
19    Q        -0.897  -0.897  -0.897  -0.871  -0.871  -0.871  -0.897  -0.897  -0.897
20    K         1.112   1.112   1.112   1.048   1.048   1.048   1.112   1.112   1.112
21    Y        -0.897  -0.897  -0.897  -0.871  -0.871  -0.871  -0.897  -0.897  -0.897
22    I        -0.897  -0.897  -0.897  -0.957  -0.957  -0.957  -0.897  -0.897  -0.897
23    N        -0.897  -0.897  -0.897  -0.864  -0.864  -0.864  -0.897  -0.897  -0.897
24    M        -0.897  -0.897  -0.897  -0.725  -0.725  -0.725  -0.897  -0.897  -0.897
25    K        -0.897  -0.897  -0.897  -1.000  -1.000  -1.000  -0.897  -0.897  -0.897
26    K         1.112   1.112   1.112   1.048   1.048   1.048   1.112   1.112   1.112
27    K        -0.897  -0.897  -0.897  -0.794  -0.794  -0.794  -0.897  -0.897  -0.897
28    E        -0.897  -0.897  -0.897  -0.850  -0.850  -0.850  -0.897  -0.897  -0.897
29    D        -0.897  -0.897  -0.897  -0.759  -0.759  -0.759  -0.897  -0.897  -0.897
30    L        -0.897  -0.897  -0.897  -0.892  -0.892  -0.892  -0.897  -0.897  -0.897
31    G        -0.897  -0.897  -0.897  -0.773  -0.773  -0.773  -0.897  -0.897  -0.897
32    V         1.112   1.112   1.112   1.175   1.175   1.175   1.112   1.112   1.112
33    C        -0.897  -0.897  -0.897  -0.857  -0.857  -0.857  -0.897  -0.897  -0.897
34    Q        -0.897  -0.897  -0.897  -0.878  -0.878  -0.878  -0.897  -0.897  -0.897
35    P        -0.897  -0.897  -0.897  -0.907  -0.907  -0.907  -0.897  -0.897  -0.897
36    G        -0.897  -0.897  -0.897  -0.829  -0.829  -0.829  -0.897  -0.897  -0.897
37    L        -0.897  -0.897  -0.897  -1.022  -1.022  -1.022  -0.897  -0.897  -0.897
38    T         1.112   1.112   1.112   1.028   1.028   1.028   1.112   1.112   1.112
39    Q        -0.897  -0.897  -0.897  -0.808  -0.808  -0.808  -0.897  -0.897  -0.897
40    K         1.112   1.112   1.112   1.048   1.048   1.048   1.112   1.112   1.112
41    A        -0.897  -0.897  -0.897  -0.794  -0.794  -0.794  -0.897  -0.897  -0.897
42    F         1.112   1.112   1.112   1.146   1.146   1.146   1.112   1.112   1.112
43    T         1.112   1.112   1.112   1.028   1.028   1.028   1.112   1.112   1.112
44    V        -0.897  -0.897  -0.897  -0.971  -0.971  -0.971  -0.897  -0.897  -0.897
45    E        -0.897  -0.897  -0.897  -1.089  -1.089  -1.089  -0.897  -0.897  -0.897
46    D        -0.897  -0.897  -0.897  -0.843  -0.843  -0.843  -0.897  -0.897  -0.897
47    K        -0.897  -0.897  -0.897  -0.935  -0.935  -0.935  -0.897  -0.897  -0.897
48    F        -0.897  -0.897  -0.897  -1.000  -1.000  -1.000  -0.897  -0.897  -0.897
49    D         1.112   1.112   1.112   1.146   1.146   1.146   1.112   1.112   1.112
50    Y        -0.897  -0.897  -0.897  -0.928  -0.928  -0.928  -0.897  -0.897  -0.897
51    K        -0.897  -0.897  -0.897  -1.074  -1.074  -1.074  -0.897  -0.897  -0.897
52    A        -0.897  -0.897  -0.897  -0.950  -0.950  -0.950  -0.897  -0.897  -0.897
53    I         1.112   1.112   1.112   1.107   1.107   1.107   1.112   1.112   1.112
54    I         1.112   1.112   1.112   1.107   1.107   1.107   1.112   1.112   1.112
55    E         1.112   1.112   1.112   1.019   1.019   1.019   1.112   1.112   1.112
56    K         1.112   1.112   1.112   1.048   1.048   1.048   1.112   1.112   1.112
57    M        -0.897  -0.897  -0.897  -0.843  -0.843  -0.843  -0.897  -0.897  -0.897
58    E         1.112   1.112   1.112   1.019   1.019   1.019   1.112   1.112   1.112
59    V        -0.897  -0.897  -0.897  -0.892  -0.892  -0.892  -0.897  -0.897  -0.897
60    Y         1.112   1.112   1.112   1.146   1.146   1.146   1.112   1.112   1.112
61    G         1.112   1.112   1.112   1.048   1.048   1.048   1.112   1.112   1.112
62    L        -0.897  -0.897  -0.897  -0.971  -0.971  -0.971  -0.897  -0.897  -0.897
63    C         1.112   1.112   1.112   1.336   1.336   1.336   1.112   1.112   1.112
64    V        -0.897  -0.897  -0.897  -0.850  -0.850  -0.850  -0.897  -0.897  -0.897
65    V         1.112   1.112   1.112   1.175   1.175   1.175   1.112   1.112   1.112
66    K        -0.897  -0.897  -0.897  -0.808  -0.808  -0.808  -0.897  -0.897  -0.897
67    N         1.112   1.112   1.112   1.117   1.117   1.117   1.112   1.112   1.112
68    F        -0.897  -0.897  -0.897  -0.993  -0.993  -0.993  -0.897  -0.897  -0.897
69    I         1.112   1.112   1.112   1.107   1.107   1.107   1.112   1.112   1.112
70    E        -0.897  -0.897  -0.897  -0.815  -0.815  -0.815  -0.897  -0.897  -0.897
71    T        -0.897  -0.897  -0.897  -1.022  -1.022  -1.022  -0.897  -0.897  -0.897
72    S        -0.897  -0.897  -0.897  -1.096  -1.096  -1.096  -0.897  -0.897  -0.897
73    R        -0.897  -0.897  -0.897  -0.808  -0.808  -0.808  -0.897  -0.897  -0.897
74    C         1.112   1.112   1.112   1.336   1.336   1.336   1.112   1.112   1.112
75    D         1.112   1.112   1.112   1.146   1.146   1.146   1.112   1.112   1.112
76    E        -0.897  -0.897  -0.897  -1.008  -1.008  -1.008  -0.897  -0.897  -0.897
77    I         1.112   1.112   1.112   1.107   1.107   1.107   1.112   1.112   1.112
78    L        -0.897  -0.897  -0.897  -0.971  -0.971  -0.971  -0.897  -0.897  -0.897
79    K        -0.897  -0.897  -0.897  -1.008  -1.008  -1.008  -0.897  -0.897  -0.897
80    E         1.112   1.112   1.112   1.019   1.019   1.019   1.112   1.112   1.112
81    I        -0.897  -0.897  -0.897  -1.022  -1.022  -1.022  -0.897  -0.897  -0.897
82    E        -0.897  -0.897  -0.897  -0.935  -0.935  -0.935  -0.897  -0.897  -0.897
83    P         1.112   1.112   1.112   1.261   1.261   1.261   1.112   1.112   1.112
84    H        -0.897  -0.897  -0.897  -0.746  -0.746  -0.746  -0.897  -0.897  -0.897
85    F         1.112   1.112   1.112   1.146   1.146   1.146   1.112   1.112   1.112
86    Y        -0.897  -0.897  -0.897  -0.843  -0.843  -0.843  -0.897  -0.897  -0.897
87    R         1.112   1.112   1.112   1.289   1.289   1.289   1.112   1.112   1.112
88    Y        -0.897  -0.897  -0.897  -0.843  -0.843  -0.843  -0.897  -0.897  -0.897
89    E         1.112   1.112   1.112   1.019   1.019   1.019   1.112   1.112   1.112
90    S        -0.897  -0.897  -0.897  -0.950  -0.950  -0.950  -0.897  -0.897  -0.897
91    W         1.112   1.112   1.112   1.448   1.448   1.448   1.112   1.112   1.112
92    Q        -0.897  -0.897  -0.897  -0.746  -0.746  -0.746  -0.897  -0.897  -0.897
93    G         1.112   1.112   1.112   1.048   1.048   1.048   1.112   1.112   1.112
94    S         1.112   1.112   1.112   0.929   0.929   0.929   1.112   1.112   1.112
95    P         1.112   1.112   1.112   1.261   1.261   1.261   1.112   1.112   1.112
96    F         1.112   1.112   1.112   1.146   1.146   1.146   1.112   1.112   1.112
97    P         1.112   1.112   1.112   1.261   1.261   1.261   1.112   1.112   1.112
98    K         1.112   1.112   1.112   1.048   1.048   1.048   1.112   1.112   1.112
99    E         1.112   1.112   1.112   1.019   1.019   1.019   1.112   1.112   1.112
100   T         1.112   1.112   1.112   1.028   1.028   1.028   1.112   1.112   1.112
101   T         1.112   1.112   1.112   1.028   1.028   1.028   1.112   1.112   1.112
102   V         1.112   1.112   1.112   1.175   1.175   1.175   1.112   1.112   1.112
103   A        -0.897  -0.897  -0.897  -0.773  -0.773  -0.773  -0.897  -0.897  -0.897
104   T         1.112   1.112   1.112   1.028   1.028   1.028   1.112   1.112   1.112
105   R         1.112   1.112   1.112   1.289   1.289   1.289   1.112   1.112   1.112
106   S         1.112   1.112   1.112   0.929   0.929   0.929   1.112   1.112   1.112
107   V        -0.897  -0.897  -0.897  -0.850  -0.850  -0.850  -0.897  -0.897  -0.897
108   L         1.112   1.112   1.112   0.939   0.939   0.939   1.112   1.112   1.112
109   H        -0.897  -0.897  -0.897  -0.815  -0.815  -0.815  -0.897  -0.897  -0.897
110   S         1.112   1.112   1.112   0.929   0.929   0.929   1.112   1.112   1.112
111   S        -0.897  -0.897  -0.897  -0.914  -0.914  -0.914  -0.897  -0.897  -0.897
112   T         1.112   1.112   1.112   1.028   1.028   1.028   1.112   1.112   1.112
113   V        -0.897  -0.897  -0.897  -0.978  -0.978  -0.978  -0.897  -0.897  -0.897
114   L        -0.897  -0.897  -0.897  -0.942  -0.942  -0.942  -0.897  -0.897  -0.897
115   K        -0.897  -0.897  -0.897  -0.914  -0.914  -0.914  -0.897  -0.897  -0.897
116   D        -0.897  -0.897  -0.897  -0.843  -0.843  -0.843  -0.897  -0.897  -0.897
117   V        -0.897  -0.897  -0.897  -0.850  -0.850  -0.850  -0.897  -0.897  -0.897
118   V        -0.897  -0.897  -0.897  -0.971  -0.971  -0.971  -0.897  -0.897  -0.897
119   C         1.112   1.112   1.112   1.336   1.336   1.336   1.112   1.112   1.112
120   D        -0.897  -0.897  -0.897  -0.864  -0.864  -0.864  -0.897  -0.897  -0.897
121   R        -0.897  -0.897  -0.897  -0.739  -0.739  -0.739  -0.897  -0.897  -0.897
122   M        -0.897  -0.897  -0.897  -0.843  -0.843  -0.843  -0.897  -0.897  -0.897
123   F         1.112   1.112   1.112   1.146   1.146   1.146   1.112   1.112   1.112
124   C        -0.897  -0.897  -0.897  -0.684  -0.684  -0.684  -0.897  -0.897  -0.897
125   D        -0.897  -0.897  -0.897  -0.725  -0.725  -0.725  -0.897  -0.897  -0.897
126   I        -0.897  -0.897  -0.897  -1.022  -1.022  -1.022  -0.897  -0.897  -0.897
127   S         1.112   1.112   1.112   0.929   0.929   0.929   1.112   1.112   1.112
128   K        -0.897  -0.897  -0.897  -1.074  -1.074  -1.074  -0.897  -0.897  -0.897
129   H        -0.897  -0.897  -0.897  -0.644  -0.644  -0.644  -0.897  -0.897  -0.897
130   F         1.112   1.112   1.112   1.146   1.146   1.146   1.112   1.112   1.112
131   L         1.112   1.112   1.112   0.939   0.939   0.939   1.112   1.112   1.112
132   N        -0.897  -0.897  -0.897  -1.022  -1.022  -1.022  -0.897  -0.897  -0.897
133   E         1.112   1.112   1.112   1.019   1.019   1.019   1.112   1.112   1.112
134   E        -0.897  -0.897  -0.897  -1.096  -1.096  -1.096  -0.897  -0.897  -0.897
135   N         1.112   1.112   1.112   1.117   1.117   1.117   1.112   1.112   1.112
136   Y         1.112   1.112   1.112   1.146   1.146   1.146   1.112   1.112   1.112
137   F         1.112   1.112   1.112   1.146   1.146   1.146   1.112   1.112   1.112
138   A        -0.897  -0.897  -0.897  -0.577  -0.577  -0.577  -0.897  -0.897  -0.897
139   A        -0.897  -0.897  -0.897  -0.878  -0.878  -0.878  -0.897  -0.897  -0.897
140   G         1.112   1.112   1.112   1.048   1.048   1.048   1.112   1.112   1.112
141   K        -0.897  -0.897  -0.897  -0.935  -0.935  -0.935  -0.897  -0.897  -0.897
142   V        -0.897  -0.897  -0.897  -0.705  -0.705  -0.705  -0.897  -0.897  -0.897
143   I         1.112   1.112   1.112   1.107   1.107   1.107   1.112   1.112   1.112
144   N        -0.897  -0.897  -0.897  -0.759  -0.759  -0.759  -0.897  -0.897  -0.897
145   K        -0.897  -0.897  -0.897  -1.008  -1.008  -1.008  -0.897  -0.897  -0.897
146   C        -0.897  -0.897  -0.897  -0.773  -0.773  -0.773  -0.897  -0.897  -0.897
147   T        -0.897  -0.897  -0.897  -1.089  -1.089  -1.089  -0.897  -0.897  -0.897
148   S         1.112   1.112   1.112   0.929   0.929   0.929   1.112   1.112   1.112
149   D        -0.897  -0.897  -0.897  -0.843  -0.843  -0.843  -0.897  -0.897  -0.897
150   I         1.112   1.112   1.112   1.107   1.107   1.107   1.112   1.112   1.112
151   Q         1.112   1.112   1.112   1.308   1.308   1.308   1.112   1.112   1.112
152   L         1.112   1.112   1.112   0.939   0.939   0.939   1.112   1.112   1.112
153   N         1.112   1.112   1.112   1.117   1.117   1.117   1.112   1.112   1.112
154   S         1.112   1.112   1.112   0.929   0.929   0.929   1.112   1.112   1.112
155   G        -0.897  -0.897  -0.897  -0.864  -0.864  -0.864  -0.897  -0.897  -0.897
156   I         1.112   1.112   1.112   1.107   1.107   1.107   1.112   1.112   1.112
157   V        -0.897  -0.897  -0.897  -0.907  -0.907  -0.907  -0.897  -0.897  -0.897
158   Y         1.112   1.112   1.112   1.146   1.146   1.146   1.112   1.112   1.112
159   K         1.112   1.112   1.112   1.048   1.048   1.048   1.112   1.112   1.112
160   V         1.112   1.112   1.112   1.175   1.175   1.175   1.112   1.112   1.112
161   G         1.112   1.112   1.112   1.048   1.048   1.048   1.112   1.112   1.112
162   A        -0.897  -0.897  -0.897  -0.711  -0.711  -0.711  -0.897  -0.897  -0.897
163   G        -0.897  -0.897  -0.897  -0.935  -0.935  -0.935  -0.897  -0.897  -0.897
164   A         1.112   1.112   1.112   1.213   1.213   1.213   1.112   1.112   1.112
165   S        -0.897  -0.897  -0.897  -1.074  -1.074  -1.074  -0.897  -0.897  -0.897
166   D         1.112   1.112   1.112   1.146   1.146   1.146   1.112   1.112   1.112
167   Q         1.112   1.112   1.112   1.308   1.308   1.308   1.112   1.112   1.112
168   G        -0.897  -0.897  -0.897  -0.766  -0.766  -0.766  -0.897  -0.897  -0.897
169   Y         1.112   1.112   1.112   1.146   1.146   1.146   1.112   1.112   1.112
170   H         1.112   1.112   1.112   1.280   1.280   1.280   1.112   1.112   1.112
171   R         1.112   1.112   1.112   1.289   1.289   1.289   1.112   1.112   1.112
172   E         1.112   1.112   1.112   1.019   1.019   1.019   1.112   1.112   1.112
173   D         1.112   1.112   1.112   1.146   1.146   1.146   1.112   1.112   1.112
174   I        -0.897  -0.897  -0.897  -0.725  -0.725  -0.725  -0.897  -0.897  -0.897
175   V        -0.897  -0.897  -0.897  -0.850  -0.850  -0.850  -0.897  -0.897  -0.897
176   H         1.112   1.112   1.112   1.280   1.280   1.280   1.112   1.112   1.112
177   H         1.112   1.112   1.112   1.280   1.280   1.280   1.112   1.112   1.112
178   T        -0.897  -0.897  -0.897  -0.950  -0.950  -0.950  -0.897  -0.897  -0.897
179   T        -0.897  -0.897  -0.897  -0.957  -0.957  -0.957  -0.897  -0.897  -0.897
180   H         1.112   1.112   1.112   1.280   1.280   1.280   1.112   1.112   1.112
181   Q        -0.897  -0.897  -0.897  -0.815  -0.815  -0.815  -0.897  -0.897  -0.897
182   A        -0.897  -0.897  -0.897  -0.885  -0.885  -0.885  -0.897  -0.897  -0.897
183   C        -0.897  -0.897  -0.897  -0.725  -0.725  -0.725  -0.897  -0.897  -0.897
184   E        -0.897  -0.897  -0.897  -0.935  -0.935  -0.935  -0.897  -0.897  -0.897
185   R        -0.897  -0.897  -0.897  -0.822  -0.822  -0.822  -0.897  -0.897  -0.897
186   F        -0.897  -0.897  -0.897  -0.843  -0.843  -0.843  -0.897  -0.897  -0.897
187   Q        -0.897  -0.897  -0.897  -0.794  -0.794  -0.794  -0.897  -0.897  -0.897
188   Y         1.112   1.112   1.112   1.146   1.146   1.146   1.112   1.112   1.112
189   G         1.112   1.112   1.112   1.048   1.048   1.048   1.112   1.112   1.112
190   T        -0.897  -0.897  -0.897  -1.089  -1.089  -1.089  -0.897  -0.897  -0.897
191   E         1.112   1.112   1.112   1.019   1.019   1.019   1.112   1.112   1.112
192   T         1.112   1.112   1.112   1.028   1.028   1.028   1.112   1.112   1.112
193   M        -0.897  -0.897  -0.897  -0.843  -0.843  -0.843  -0.897  -0.897  -0.897
194   V        -0.897  -0.897  -0.897  -0.971  -0.971  -0.971  -0.897  -0.897  -0.897
195   G         1.112   1.112   1.112   1.048   1.048   1.048   1.112   1.112   1.112
196   L         1.112   1.112   1.112   0.939   0.939   0.939   1.112   1.112   1.112
197   G        -0.897  -0.897  -0.897  -1.074  -1.074  -1.074  -0.897  -0.897  -0.897
198   V        -0.897  -0.897  -0.897  -0.850  -0.850  -0.850  -0.897  -0.897  -0.897
199   A         1.112   1.112   1.112   1.213   1.213   1.213   1.112   1.112   1.112
200   F        -0.897  -0.897  -0.897  -0.993  -0.993  -0.993  -0.897  -0.897  -0.897
201   T         1.112   1.112   1.112   1.028   1.028   1.028   1.112   1.112   1.112
202   D         1.112   1.112   1.112   1.146   1.146   1.146   1.112   1.112   1.112
203   M        -0.897  -0.897  -0.897  -0.780  -0.780  -0.780  -0.897  -0.897  -0.897
204   N        -0.897  -0.897  -0.897  -0.950  -0.950  -0.950  -0.897  -0.897  -0.897
205   K         1.112   1.112   1.112   1.048   1.048   1.048   1.112   1.112   1.112
206   E        -0.897  -0.897  -0.897  -0.885  -0.885  -0.885  -0.897  -0.897  -0.897
207   N         1.112   1.112   1.112   1.117   1.117   1.117   1.112   1.112   1.112
208   G         1.112   1.112   1.112   1.048   1.048   1.048   1.112   1.112   1.112
209   S        -0.897  -0.897  -0.897  -0.950  -0.950  -0.950  -0.897  -0.897  -0.897
210   T         1.112   1.112   1.112   1.028   1.028   1.028   1.112   1.112   1.112
211   R         1.112   1.112   1.112   1.289   1.289   1.289   1.112   1.112   1.112
212   M        -0.897  -0.897  -0.897  -0.677  -0.677  -0.677  -0.897  -0.897  -0.897
213   I         1.112   1.112   1.112   1.107   1.107   1.107   1.112   1.112   1.112
214   V        -0.897  -0.897  -0.897  -0.739  -0.739  -0.739  -0.897  -0.897  -0.897
215   G         1.112   1.112   1.112   1.048   1.048   1.048   1.112   1.112   1.112
216   S         1.112   1.112   1.112   0.929   0.929   0.929   1.112   1.112   1.112
217   H         1.112   1.112   1.112   1.280   1.280   1.280   1.112   1.112   1.112
218   L         1.112   1.112   1.112   0.939   0.939   0.939   1.112   1.112   1.112
219   W         1.112   1.112   1.112   1.448   1.448   1.448   1.112   1.112   1.112
220   G         1.112   1.112   1.112   1.048   1.048   1.048   1.112   1.112   1.112
221   P         1.112   1.112   1.112   1.261   1.261   1.261   1.112   1.112   1.112
222   H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
223   D        -0.897  -0.897  -0.897  -0.864  -0.864  -0.864  -0.897  -0.897  -0.897
224   S        -0.897  -0.897  -0.897  -0.892  -0.892  -0.892  -0.897  -0.897  -0.897
225   C         1.112   1.112   1.112   1.336   1.336   1.336   1.112   1.112   1.112
226   G        -0.897  -0.897  -0.897  -0.829  -0.829  -0.829  -0.897  -0.897  -0.897
227   N        -0.897  -0.897  -0.897  -0.864  -0.864  -0.864  -0.897  -0.897  -0.897
228   F        -0.897  -0.897  -0.897  -0.864  -0.864  -0.864  -0.897  -0.897  -0.897
229   D        -0.897  -0.897  -0.897  -0.864  -0.864  -0.864  -0.897  -0.897  -0.897
230   K        -0.897  -0.897  -0.897  -1.008  -1.008  -1.008  -0.897  -0.897  -0.897
231   R        -0.897  -0.897  -0.897  -0.808  -0.808  -0.808  -0.897  -0.897  -0.897
232   M        -0.897  -0.897  -0.897  -0.718  -0.718  -0.718  -0.897  -0.897  -0.897
233   E        -0.897  -0.897  -0.897  -0.885  -0.885  -0.885  -0.897  -0.897  -0.897
234   F        -0.897  -0.897  -0.897  -0.705  -0.705  -0.705  -0.897  -0.897  -0.897
235   H        -0.897  -0.897  -0.897  -0.746  -0.746  -0.746  -0.897  -0.897  -0.897
236   V        -0.897  -0.897  -0.897  -0.971  -0.971  -0.971  -0.897  -0.897  -0.897
237   N        -0.897  -0.897  -0.897  -0.957  -0.957  -0.957  -0.897  -0.897  -0.897
238   V        -0.897  -0.897  -0.897  -0.971  -0.971  -0.971  -0.897  -0.897  -0.897
239   A        -0.897  -0.897  -0.897  -0.885  -0.885  -0.885  -0.897  -0.897  -0.897
240   K         1.112   1.112   1.112   1.048   1.048   1.048   1.112   1.112   1.112
241   G         1.112   1.112   1.112   1.048   1.048   1.048   1.112   1.112   1.112
242   D         1.112   1.112   1.112   1.146   1.146   1.146   1.112   1.112   1.112
243   A        -0.897  -0.897  -0.897  -0.657  -0.657  -0.657  -0.897  -0.897  -0.897
244   V        -0.897  -0.897  -0.897  -0.773  -0.773  -0.773  -0.897  -0.897  -0.897
245   L        -0.897  -0.897  -0.897  -0.993  -0.993  -0.993  -0.897  -0.897  -0.897
246   F        -0.897  -0.897  -0.897  -0.871  -0.871  -0.871  -0.897  -0.897  -0.897
247   L         1.112   1.112   1.112   0.939   0.939   0.939   1.112   1.112   1.112
248   G         1.112   1.112   1.112   1.048   1.048   1.048   1.112   1.112   1.112
249   S         1.112   1.112   1.112   0.929   0.929   0.929   1.112   1.112   1.112
250   L        -0.897  -0.897  -0.897  -1.081  -1.081  -1.081  -0.897  -0.897  -0.897
251   Y         1.112   1.112   1.112   1.146   1.146   1.146   1.112   1.112   1.112
252   H         1.112   1.112   1.112   1.280   1.280   1.280   1.112   1.112   1.112
253   A         1.112   1.112   1.112   1.213   1.213   1.213   1.112   1.112   1.112
254   A         1.112   1.112   1.112   1.213   1.213   1.213   1.112   1.112   1.112
255   S         1.112   1.112   1.112   0.929   0.929   0.929   1.112   1.112   1.112
256   A        -0.897  -0.897  -0.897  -0.950  -0.950  -0.950  -0.897  -0.897  -0.897
257   N         1.112   1.112   1.112   1.117   1.117   1.117   1.112   1.112   1.112
258   R        -0.897  -0.897  -0.897  -0.597  -0.597  -0.597  -0.897  -0.897  -0.897
259   T         1.112   1.112   1.112   1.028   1.028   1.028   1.112   1.112   1.112
260   S         1.112   1.112   1.112   0.929   0.929   0.929   1.112   1.112   1.112
261   Q        -0.897  -0.897  -0.897  -0.815  -0.815  -0.815  -0.897  -0.897  -0.897
262   D         1.112   1.112   1.112   1.146   1.146   1.146   1.112   1.112   1.112
263   R         1.112   1.112   1.112   1.289   1.289   1.289   1.112   1.112   1.112
264   V        -0.897  -0.897  -0.897  -0.850  -0.850  -0.850  -0.897  -0.897  -0.897
265   A        -0.897  -0.897  -0.897  -0.878  -0.878  -0.878  -0.897  -0.897  -0.897
266   G        -0.897  -0.897  -0.897  -1.074  -1.074  -1.074  -0.897  -0.897  -0.897
267   Y        -0.897  -0.897  -0.897  -0.843  -0.843  -0.843  -0.897  -0.897  -0.897
268   F        -0.897  -0.897  -0.897  -0.843  -0.843  -0.843  -0.897  -0.897  -0.897
269   F         1.112   1.112   1.112   1.146   1.146   1.146   1.112   1.112   1.112
270   M         1.112   1.112   1.112   1.346   1.346   1.346   1.112   1.112   1.112
271   T         1.112   1.112   1.112   1.028   1.028   1.028   1.112   1.112   1.112
272   K         1.112   1.112   1.112   1.048   1.048   1.048   1.112   1.112   1.112
273   S         1.112   1.112   1.112   0.929   0.929   0.929   1.112   1.112   1.112
274   Y         1.112   1.112   1.112   1.146   1.146   1.146   1.112   1.112   1.112
275   L         1.112   1.112   1.112   0.939   0.939   0.939   1.112   1.112   1.112
276   K         1.112   1.112   1.112   1.048   1.048   1.048   1.112   1.112   1.112
277   P        -0.897  -0.897  -0.897  -0.644  -0.644  -0.644  -0.897  -0.897  -0.897
278   E         1.112   1.112   1.112   1.019   1.019   1.019   1.112   1.112   1.112
279   E         1.112   1.112   1.112   1.019   1.019   1.019   1.112   1.112   1.112
280   N         1.112   1.112   1.112   1.117   1.117   1.117   1.112   1.112   1.112
281   L        -0.897  -0.897  -0.897  -0.993  -0.993  -0.993  -0.897  -0.897  -0.897
282   H        -0.897  -0.897  -0.897  -0.746  -0.746  -0.746  -0.897  -0.897  -0.897
283   L         1.112   1.112   1.112   0.939   0.939   0.939   1.112   1.112   1.112
284   G        -0.897  -0.897  -0.897  -0.914  -0.914  -0.914  -0.897  -0.897  -0.897
285   T        -0.897  -0.897  -0.897  -1.000  -1.000  -1.000  -0.897  -0.897  -0.897
286   D        -0.897  -0.897  -0.897  -0.864  -0.864  -0.864  -0.897  -0.897  -0.897
287   L        -0.897  -0.897  -0.897  -0.971  -0.971  -0.971  -0.897  -0.897  -0.897
288   R        -0.897  -0.897  -0.897  -0.892  -0.892  -0.892  -0.897  -0.897  -0.897
289   V        -0.897  -0.897  -0.897  -0.822  -0.822  -0.822  -0.897  -0.897  -0.897
290   F         1.112   1.112   1.112   1.146   1.146   1.146   1.112   1.112   1.112
291   K        -0.897  -0.897  -0.897  -1.000  -1.000  -1.000  -0.897  -0.897  -0.897
292   G        -0.897  -0.897  -0.897  -0.986  -0.986  -0.986  -0.897  -0.897  -0.897
293   L        -0.897  -0.897  -0.897  -0.993  -0.993  -0.993  -0.897  -0.897  -0.897
294   P        -0.897  -0.897  -0.897  -0.914  -0.914  -0.914  -0.897  -0.897  -0.897
295   L        -0.897  -0.897  -0.897  -1.015  -1.015  -1.015  -0.897  -0.897  -0.897
296   E        -0.897  -0.897  -0.897  -0.964  -0.964  -0.964  -0.897  -0.897  -0.897
297   A         1.112   1.112   1.112   1.213   1.213   1.213   1.112   1.112   1.112
298   L         1.112   1.112   1.112   0.939   0.939   0.939   1.112   1.112   1.112
299   Q        -0.897  -0.897  -0.897  -0.624  -0.624  -0.624  -0.897  -0.897  -0.897
300   L         1.112   1.112   1.112   0.939   0.939   0.939   1.112   1.112   1.112
301   L         1.112   1.112   1.112   0.939   0.939   0.939   1.112   1.112   1.112
302   G         1.112   1.112   1.112   1.048   1.048   1.048   1.112   1.112   1.112
303   L         1.112   1.112   1.112   0.939   0.939   0.939   1.112   1.112   1.112
304   G        -0.897  -0.897  -0.897  -0.914  -0.914  -0.914  -0.897  -0.897  -0.897
305   I        -0.897  -0.897  -0.897  -1.022  -1.022  -1.022  -0.897  -0.897  -0.897
306   S         1.112   1.112   1.112   0.929   0.929   0.929   1.112   1.112   1.112
307   E         1.112   1.112   1.112   1.019   1.019   1.019   1.112   1.112   1.112
308   P         1.112   1.112   1.112   1.261   1.261   1.261   1.112   1.112   1.112
309   F         1.112   1.112   1.112   1.146   1.146   1.146   1.112   1.112   1.112
310   C         1.112   1.112   1.112   1.336   1.336   1.336   1.112   1.112   1.112
311   G         1.112   1.112   1.112   1.048   1.048   1.048   1.112   1.112   1.112
312   H         1.112   1.112   1.112   1.280   1.280   1.280   1.112   1.112   1.112
313   I        -0.897  -0.897  -0.897  -0.725  -0.725  -0.725  -0.897  -0.897  -0.897
314   D         1.112   1.112   1.112   1.146   1.146   1.146   1.112   1.112   1.112
315   Y         1.112   1.112   1.112   1.146   1.146   1.146   1.112   1.112   1.112
316   K        -0.897  -0.897  -0.897  -0.766  -0.766  -0.766  -0.897  -0.897  -0.897
317   S        -0.897  -0.897  -0.897  -1.022  -1.022  -1.022  -0.897  -0.897  -0.897
318   P         1.112   1.112   1.112   1.261   1.261   1.261   1.112   1.112   1.112
319   G        -0.897  -0.897  -0.897  -0.942  -0.942  -0.942  -0.897  -0.897  -0.897
320   H        -0.897  -0.897  -0.897  -0.892  -0.892  -0.892  -0.897  -0.897  -0.897
321   L         1.112   1.112   1.112   0.939   0.939   0.939   1.112   1.112   1.112
322   I        -0.897  -0.897  -0.897  -0.871  -0.871  -0.871  -0.897  -0.897  -0.897
323   S        -0.897  -0.897  -0.897  -1.089  -1.089  -1.089  -0.897  -0.897  -0.897
324   S        -0.897  -0.897  -0.897  -0.950  -0.950  -0.950  -0.897  -0.897  -0.897
325   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
326   S         1.112   1.112   1.112   0.929   0.929   0.929   1.112   1.112   1.112
327   L        -0.897  -0.897  -0.897  -1.156  -1.156  -1.156  -0.897  -0.897  -0.897
328   F         1.112   1.112   1.112   1.146   1.146   1.146   1.112   1.112   1.112
329   E         1.112   1.112   1.112   1.019   1.019   1.019   1.112   1.112   1.112
330   N        -0.897  -0.897  -0.897  -0.957  -0.957  -0.957  -0.897  -0.897  -0.897
331   D        -0.897  -0.897  -0.897  -1.000  -1.000  -1.000  -0.897  -0.897  -0.897
332   I        -0.897  -0.897  -0.897  -0.957  -0.957  -0.957  -0.897  -0.897  -0.897
333   E        -0.897  -0.897  -0.897  -0.850  -0.850  -0.850  -0.897  -0.897  -0.897
334   K         1.112   1.112   1.112   1.048   1.048   1.048   1.112   1.112   1.112
335   G        -0.897  -0.897  -0.897  -0.914  -0.914  -0.914  -0.897  -0.897  -0.897
336   Y        -0.897  -0.897  -0.897  -0.725  -0.725  -0.725  -0.897  -0.897  -0.897
337   Y        -0.897  -0.897  -0.897  -0.864  -0.864  -0.864  -0.897  -0.897  -0.897
338   G        -0.897  -0.897  -0.897  -0.986  -0.986  -0.986  -0.897  -0.897  -0.897
339   E        -0.897  -0.897  -0.897  -0.957  -0.957  -0.957  -0.897  -0.897  -0.897
340   T        -0.897  -0.897  -0.897  -0.928  -0.928  -0.928  -0.897  -0.897  -0.897
341   I        -0.897  -0.897  -0.897  -0.957  -0.957  -0.957  -0.897  -0.897  -0.897
342   R        -0.897  -0.897  -0.897  -0.829  -0.829  -0.829  -0.897  -0.897  -0.897
343   V        -0.897  -0.897  -0.897  -0.907  -0.907  -0.907  -0.897  -0.897  -0.897
344   N        -0.897  -0.897  -0.897  -0.892  -0.892  -0.892  -0.897  -0.897  -0.897
345   Y         1.112   1.112   1.112   1.146   1.146   1.146   1.112   1.112   1.112
346   G        -0.897  -0.897  -0.897  -0.829  -0.829  -0.829  -0.897  -0.897  -0.897
347   S         1.112   1.112   1.112   0.929   0.929   0.929   1.112   1.112   1.112
348   T        -0.897  -0.897  -0.897  -0.928  -0.928  -0.928  -0.897  -0.897  -0.897
349   Q        -0.897  -0.897  -0.897  -0.808  -0.808  -0.808  -0.897  -0.897  -0.897
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P47181
Output conservation file - output/P47181
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
