1     M         1.642   1.665   1.759   1.858   1.891   2.037   1.815   1.849   1.999
2     K        -0.802  -0.754  -0.720  -0.919  -0.840  -0.787  -0.872  -0.815  -0.745
3     V        -0.802  -0.811  -0.739  -0.779  -0.794  -0.703  -0.872  -0.875  -0.764
4     E        -0.269  -0.275  -0.209  -0.587  -0.596  -0.517  -0.510  -0.527  -0.432
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
19    Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
20    E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
21    D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
22    D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
23    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
24    E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
25    G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
26    F        -0.105  -0.187  -0.166  -0.128  -0.279  -0.276  -0.268  -0.391  -0.371
27    S         1.642   1.665   1.759   1.707   1.742   1.886   1.815   1.849   1.999
28    F        -0.705  -0.738  -0.708  -0.778  -0.829  -0.787  -0.766  -0.798  -0.731
29    L         0.178   0.259   0.001   0.117   0.231  -0.164   0.145   0.261  -0.123
30    E        -0.705  -0.660  -0.687  -0.838  -0.781  -0.783  -0.766  -0.721  -0.710
31    I        -0.115  -0.175  -0.140  -0.289  -0.377  -0.367  -0.311  -0.379  -0.343
32    M         0.178   0.123  -0.027   0.291   0.194  -0.012   0.145   0.054  -0.165
33    D        -1.069  -1.096  -1.114  -0.889  -0.947  -0.960  -0.918  -0.946  -0.923
34    R        -0.115  -0.019  -0.109  -0.192  -0.040  -0.198  -0.311  -0.174  -0.293
35    V         0.178   0.203  -0.019   0.223   0.261  -0.039   0.145   0.179  -0.153
36    D         1.642   1.665   1.759   1.669   1.700   1.849   1.815   1.849   1.999
37    P        -0.479  -0.503  -0.614  -0.312  -0.360  -0.545  -0.463  -0.499  -0.615
38    L        -0.115  -0.096  -0.122  -0.200  -0.153  -0.215  -0.311  -0.273  -0.312
39    P         0.814   0.844   0.710   0.921   0.961   0.759   0.782   0.827   0.560
40    L        -0.642  -0.545  -0.654  -0.578  -0.421  -0.627  -0.665  -0.542  -0.662
41    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
42    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
43    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
44    D         0.608   0.674   0.610   0.581   0.683   0.559   0.420   0.532   0.367
45    F        -0.269  -0.291  -0.218  -0.326  -0.370  -0.261  -0.510  -0.548  -0.447
46    E         0.608   0.674   0.610   0.394   0.490   0.385   0.420   0.532   0.367
47    N        -0.269  -0.297  -0.212  -0.407  -0.467  -0.352  -0.510  -0.555  -0.438
48    Y         0.368   0.393   0.496   0.192   0.237   0.390  -0.045  -0.007   0.140
49    K        -0.269  -0.275  -0.209  -0.548  -0.561  -0.454  -0.510  -0.527  -0.432
50    N        -1.571  -1.489  -1.463  -1.251  -1.119  -1.103  -1.222  -1.143  -1.070
51    F        -1.069  -1.096  -1.114  -1.016  -1.060  -1.147  -0.918  -0.946  -0.923
52    K        -1.935  -1.900  -1.793  -1.614  -1.551  -1.407  -1.374  -1.338  -1.196
53    E        -0.705  -0.650  -0.676  -0.825  -0.717  -0.778  -0.766  -0.691  -0.697
54    G        -1.571  -1.553  -1.485  -1.366  -1.338  -1.251  -1.222  -1.200  -1.088
55    I        -0.705  -0.724  -0.704  -0.778  -0.796  -0.782  -0.766  -0.781  -0.727
56    Y         0.888   0.929   0.745   1.006   1.068   0.804   0.904   0.967   0.624
57    Y        -1.207  -1.239  -1.152  -1.112  -1.154  -1.010  -1.070  -1.088  -0.961
58    M        -0.341  -0.335  -0.234  -0.531  -0.521  -0.360  -0.614  -0.608  -0.469
59    C        -1.571  -1.527  -1.471  -1.433  -1.401  -1.292  -1.222  -1.179  -1.077
60    T        -0.705  -0.752  -0.702  -0.608  -0.669  -0.574  -0.766  -0.812  -0.725
61    H         0.888   0.765   0.714   1.136   0.954   0.845   0.904   0.694   0.567
62    D         0.178   0.183  -0.017   0.281   0.283  -0.039   0.145   0.151  -0.150
63    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
64    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
65    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
66    G        -0.479  -0.490  -0.624  -0.285  -0.298  -0.488  -0.463  -0.483  -0.627
67    T        -0.341  -0.292  -0.217  -0.589  -0.528  -0.402  -0.614  -0.544  -0.446
68    K        -1.207  -1.126  -1.132  -1.206  -1.078  -1.096  -1.070  -0.988  -0.944
69    I        -0.204  -0.171  -0.167  -0.510  -0.456  -0.443  -0.463  -0.421  -0.387
70    G         1.642   1.665   1.759   1.652   1.687   1.832   1.815   1.849   1.999
71    F         0.387   0.427   0.512   0.192   0.267   0.384  -0.007   0.061   0.173
72    V        -0.115  -0.086  -0.125  -0.335  -0.282  -0.367  -0.311  -0.256  -0.316
73    L        -1.207  -1.207  -1.139  -1.237  -1.240  -1.113  -1.070  -1.062  -0.950
74    K        -0.705  -0.738  -0.705  -0.738  -0.800  -0.750  -0.766  -0.793  -0.728
75    F        -1.207  -1.208  -1.130  -1.266  -1.273  -1.144  -1.070  -1.062  -0.942
76    A        -0.204  -0.142  -0.159  -0.443  -0.370  -0.353  -0.463  -0.388  -0.378
77    I        -1.069  -0.933  -1.065  -1.090  -0.890  -1.095  -0.918  -0.766  -0.876
78    N        -1.935  -1.900  -1.793  -1.779  -1.737  -1.571  -1.374  -1.338  -1.196
79    E        -0.479  -0.490  -0.624  -0.481  -0.506  -0.689  -0.463  -0.483  -0.627
80    M        -0.843  -0.787  -0.741  -0.978  -0.920  -0.808  -0.918  -0.856  -0.767
81    E        -1.207  -1.239  -1.130  -1.130  -1.163  -1.008  -1.070  -1.088  -0.943
82    T        -1.571  -1.460  -1.470  -1.422  -1.257  -1.274  -1.222  -1.116  -1.076
83    V        -0.705  -0.735  -0.707  -0.912  -0.963  -0.899  -0.766  -0.796  -0.731
84    C        -1.207  -1.174  -1.130  -0.921  -0.900  -0.809  -1.070  -1.031  -0.942
85    S        -1.207  -1.217  -1.135  -1.113  -1.130  -0.998  -1.070  -1.070  -0.946
86    E        -0.297  -0.241  -0.207  -0.570  -0.468  -0.416  -0.566  -0.490  -0.435
87    I        -0.269  -0.177  -0.190  -0.637  -0.471  -0.535  -0.510  -0.375  -0.405
88    F        -0.906  -0.865  -0.772  -1.080  -1.018  -0.878  -0.975  -0.925  -0.797
89    E        -0.906  -0.865  -0.772  -1.187  -1.099  -0.984  -0.975  -0.925  -0.797
90    E        -0.269  -0.291  -0.218  -0.480  -0.496  -0.385  -0.510  -0.548  -0.447
91    T         0.608   0.702   0.614   0.439   0.582   0.436   0.420   0.583   0.376
92    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
93    F        -0.479  -0.562  -0.642  -0.390  -0.541  -0.708  -0.463  -0.569  -0.648
94    Q        -1.571  -1.564  -1.480  -1.471  -1.434  -1.314  -1.222  -1.209  -1.084
95    L        -0.843  -0.795  -0.735  -1.131  -1.051  -0.953  -0.918  -0.865  -0.762
96    D         0.178   0.239  -0.005   0.322   0.407   0.050   0.145   0.233  -0.132
97    E        -1.207  -1.195  -1.136  -1.326  -1.327  -1.207  -1.070  -1.053  -0.947
98    S        -1.207  -1.174  -1.123  -1.125  -1.068  -0.995  -1.070  -1.031  -0.937
99    R        -1.571  -1.539  -1.482  -1.440  -1.392  -1.311  -1.222  -1.189  -1.085
100   H        -1.069  -1.071  -1.108  -0.802  -0.815  -0.830  -0.918  -0.919  -0.918
101   E        -0.479  -0.377  -0.604  -0.365  -0.211  -0.594  -0.463  -0.332  -0.603
102   L        -0.204  -0.142  -0.159  -0.561  -0.472  -0.471  -0.463  -0.385  -0.377
103   R        -1.207  -1.207  -1.139  -1.116  -1.143  -1.012  -1.070  -1.062  -0.950
104   F        -0.204  -0.267  -0.182  -0.380  -0.470  -0.352  -0.463  -0.526  -0.405
105   K        -1.069  -1.096  -1.114  -0.984  -1.034  -1.081  -0.918  -0.946  -0.923
106   S        -1.207  -1.241  -1.131  -1.091  -1.142  -0.971  -1.070  -1.090  -0.944
107   E        -1.571  -1.578  -1.482  -1.463  -1.457  -1.307  -1.222  -1.220  -1.085
108   -        -0.105  -0.093  -0.123  -0.252  -0.245  -0.293  -0.268  -0.259  -0.308
109   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
110   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
111   -         0.608   0.540   0.579   0.549   0.429   0.469   0.420   0.283   0.306
112   D        -0.341  -0.280  -0.220  -0.489  -0.388  -0.307  -0.614  -0.526  -0.449
113   F        -0.479  -0.562  -0.642  -0.306  -0.429  -0.573  -0.463  -0.569  -0.648
114   D        -0.115  -0.043  -0.125  -0.276  -0.167  -0.260  -0.311  -0.204  -0.317
115   H        -0.705  -0.663  -0.699  -0.765  -0.734  -0.743  -0.766  -0.726  -0.723
116   R         1.642   1.665   1.759   1.718   1.746   1.898   1.815   1.849   1.999
117   N        -0.479  -0.578  -0.644  -0.258  -0.410  -0.531  -0.463  -0.588  -0.651
118   N        -1.571  -1.574  -1.496  -1.418  -1.450  -1.324  -1.222  -1.217  -1.096
119   L         0.178   0.178  -0.016   0.171   0.166  -0.100   0.145   0.144  -0.148
120   I        -1.069  -1.071  -1.108  -1.007  -1.029  -1.122  -0.918  -0.919  -0.918
121   D        -1.207  -1.195  -1.136  -1.218  -1.216  -1.091  -1.070  -1.053  -0.947
122   Q        -1.207  -1.113  -1.128  -1.294  -1.149  -1.157  -1.070  -0.978  -0.941
123   L         0.542   0.618   0.603   0.288   0.412   0.366   0.297   0.429   0.354
124   A        -0.705  -0.729  -0.681  -0.635  -0.675  -0.571  -0.766  -0.782  -0.702
125   R        -1.935  -1.900  -1.793  -1.663  -1.627  -1.456  -1.374  -1.338  -1.196
126   K        -0.115  -0.099  -0.142  -0.206  -0.221  -0.255  -0.311  -0.310  -0.347
127   M        -0.115  -0.030  -0.130   0.014   0.142  -0.020  -0.311  -0.194  -0.327
128   Y         0.888   0.969   0.755   1.035   1.138   0.847   0.904   1.030   0.642
129   L        -1.935  -1.900  -1.793  -1.876  -1.856  -1.668  -1.374  -1.338  -1.196
130   E        -1.207  -1.113  -1.128  -1.122  -0.954  -1.012  -1.070  -0.978  -0.941
131   S        -0.705  -0.770  -0.711  -0.725  -0.833  -0.758  -0.766  -0.824  -0.733
132   S        -1.571  -1.553  -1.485  -1.543  -1.521  -1.432  -1.222  -1.200  -1.088
133   L         0.387   0.427   0.512   0.082   0.164   0.274  -0.007   0.061   0.173
134   S        -1.571  -1.575  -1.478  -1.319  -1.342  -1.182  -1.222  -1.218  -1.082
135   G        -1.207  -1.239  -1.152  -1.273  -1.319  -1.163  -1.070  -1.088  -0.961
136   V        -0.705  -0.619  -0.676  -0.931  -0.796  -0.866  -0.766  -0.659  -0.694
137   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
138   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
139   K         0.888   0.867   0.732   0.937   0.913   0.686   0.904   0.867   0.600
140   G         0.178   0.093  -0.040   0.306   0.184  -0.022   0.145   0.015  -0.185
141   W         1.642   1.665   1.759   1.892   1.923   2.071   1.815   1.849   1.999
142   R         1.642   1.665   1.759   1.718   1.746   1.898   1.815   1.849   1.999
143   N         0.888   0.935   0.747   1.049   1.120   0.845   0.904   0.976   0.628
144   E         1.642   1.665   1.759   1.494   1.529   1.676   1.815   1.849   1.999
145   K         0.387   0.398   0.498   0.048   0.056   0.202  -0.007   0.004   0.144
146   Y         0.888   0.765   0.714   1.039   0.888   0.820   0.904   0.694   0.567
147   A        -0.115  -0.164  -0.137  -0.105  -0.181  -0.142  -0.311  -0.361  -0.333
148   V         0.888   0.867   0.732   0.844   0.818   0.618   0.904   0.867   0.600
149   W         0.542   0.604   0.594   0.559   0.656   0.633   0.297   0.404   0.336
150   -         0.608   0.540   0.579   0.668   0.546   0.572   0.420   0.283   0.306
151   V        -0.204  -0.267  -0.182  -0.400  -0.477  -0.339  -0.463  -0.526  -0.405
152   N        -1.207  -1.147  -1.125  -1.167  -1.072  -1.052  -1.070  -1.009  -0.938
153   K        -0.705  -0.660  -0.679  -0.624  -0.558  -0.575  -0.766  -0.706  -0.701
154   K        -0.843  -0.797  -0.741  -1.083  -1.026  -0.937  -0.918  -0.867  -0.767
155   P         0.178   0.035  -0.061   0.278   0.047  -0.145   0.145  -0.066  -0.216
156   Y         0.888   0.765   0.714   0.980   0.805   0.701   0.904   0.694   0.567
157   V        -0.115  -0.117  -0.155  -0.225  -0.255  -0.258  -0.311  -0.341  -0.366
158   L         0.178   0.112  -0.038   0.196   0.096  -0.091   0.145   0.041  -0.182
159   V        -0.115  -0.096  -0.122  -0.206  -0.155  -0.199  -0.311  -0.273  -0.312
160   E         1.642   1.665   1.759   1.494   1.529   1.676   1.815   1.849   1.999
161   R         1.642   1.665   1.759   1.718   1.746   1.898   1.815   1.849   1.999
162   A         0.888   0.935   0.747   1.027   1.075   0.822   0.904   0.976   0.628
163   V        -0.843  -0.870  -0.743  -1.085  -1.120  -0.927  -0.918  -0.932  -0.769
164   A        -0.705  -0.774  -0.701  -0.605  -0.690  -0.576  -0.766  -0.829  -0.723
165   G        -0.115  -0.086  -0.125  -0.225  -0.162  -0.238  -0.311  -0.256  -0.316
166   V        -0.115  -0.043  -0.125  -0.360  -0.248  -0.368  -0.311  -0.204  -0.317
167   L        -0.204  -0.146  -0.160  -0.442  -0.340  -0.349  -0.463  -0.389  -0.378
168   G         1.642   1.665   1.759   1.652   1.687   1.832   1.815   1.849   1.999
169   I        -0.204  -0.267  -0.182  -0.452  -0.530  -0.396  -0.463  -0.526  -0.405
170   I        -0.204  -0.267  -0.167  -0.452  -0.530  -0.375  -0.463  -0.525  -0.387
171   T         0.888   0.765   0.714   1.005   0.834   0.757   0.904   0.694   0.567
172   Y         1.642   1.665   1.759   1.688   1.725   1.868   1.815   1.849   1.999
173   G         1.642   1.665   1.759   1.652   1.687   1.832   1.815   1.849   1.999
174   I         0.888   0.969   0.755   0.844   0.951   0.655   0.904   1.030   0.642
175   H         1.642   1.665   1.759   1.851   1.884   2.030   1.815   1.849   1.999
176   I        -0.115  -0.186  -0.146  -0.206  -0.284  -0.246  -0.311  -0.396  -0.350
177   N         0.888   0.867   0.732   1.027   1.006   0.779   0.904   0.867   0.600
178   G         0.888   0.765   0.714   0.974   0.806   0.727   0.904   0.694   0.567
179   Y         0.387   0.389   0.494   0.192   0.191   0.347  -0.007  -0.015   0.135
180   V        -0.705  -0.681  -0.686  -0.786  -0.759  -0.725  -0.766  -0.742  -0.709
181   L        -0.705  -0.663  -0.699  -0.708  -0.657  -0.711  -0.766  -0.726  -0.723
182   D        -0.705  -0.770  -0.711  -0.695  -0.783  -0.696  -0.766  -0.824  -0.733
183   P        -1.571  -1.564  -1.480  -1.412  -1.381  -1.250  -1.222  -1.209  -1.084
184   K        -1.207  -1.205  -1.127  -1.089  -1.090  -0.953  -1.070  -1.061  -0.940
185   S        -0.115  -0.142  -0.157  -0.101  -0.177  -0.177  -0.311  -0.370  -0.369
186   K        -0.705  -0.656  -0.687  -0.650  -0.574  -0.610  -0.766  -0.706  -0.709
187   K        -1.207  -1.226  -1.147  -1.236  -1.254  -1.139  -1.070  -1.078  -0.956
188   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
189   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
190   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
191   V        -0.705  -0.665  -0.689  -0.899  -0.836  -0.867  -0.766  -0.714  -0.711
192   Q        -0.115  -0.113  -0.152  -0.111  -0.142  -0.153  -0.311  -0.337  -0.362
193   F        -0.115  -0.122  -0.160  -0.110  -0.155  -0.178  -0.311  -0.347  -0.373
194   W         1.642   1.665   1.759   1.892   1.923   2.071   1.815   1.849   1.999
195   V         0.542   0.586   0.577   0.316   0.386   0.345   0.297   0.371   0.303
196   P         1.642   1.665   1.759   1.692   1.724   1.872   1.815   1.849   1.999
197   R         0.542   0.475   0.528   0.496   0.359   0.418   0.297   0.157   0.205
198   R         1.642   1.665   1.759   1.718   1.746   1.898   1.815   1.849   1.999
199   S         0.888   0.867   0.732   1.028   1.003   0.808   0.904   0.867   0.600
200   K        -0.115  -0.096  -0.122  -0.161  -0.137  -0.195  -0.311  -0.273  -0.312
201   T         0.888   0.929   0.745   0.997   1.051   0.792   0.904   0.967   0.624
202   K         1.642   1.665   1.759   1.652   1.688   1.832   1.815   1.849   1.999
203   Q         0.178   0.123  -0.027   0.378   0.289   0.093   0.145   0.054  -0.165
204   T         1.642   1.665   1.759   1.683   1.713   1.863   1.815   1.849   1.999
205   W         0.387   0.398   0.498   0.356   0.364   0.508  -0.007   0.004   0.144
206   P         1.642   1.665   1.759   1.692   1.724   1.872   1.815   1.849   1.999
207   L        -0.705  -0.663  -0.699  -0.750  -0.690  -0.749  -0.766  -0.726  -0.723
208   M        -0.479  -0.435  -0.593  -0.190  -0.122  -0.411  -0.463  -0.405  -0.590
209   L         1.642   1.665   1.759   1.506   1.538   1.688   1.815   1.849   1.999
210   D         1.642   1.665   1.759   1.669   1.700   1.849   1.815   1.849   1.999
211   N         1.642   1.665   1.759   1.735   1.775   1.914   1.815   1.849   1.999
212   I        -0.705  -0.738  -0.705  -0.748  -0.794  -0.757  -0.766  -0.793  -0.728
213   I         0.542   0.604   0.594   0.316   0.417   0.377   0.297   0.404   0.336
214   A         1.642   1.665   1.759   1.716   1.732   1.896   1.815   1.849   1.999
215   G         1.642   1.665   1.759   1.652   1.687   1.832   1.815   1.849   1.999
216   G         1.642   1.665   1.759   1.652   1.687   1.832   1.815   1.849   1.999
217   L         0.178   0.183  -0.017   0.117   0.121  -0.195   0.145   0.151  -0.150
218   G         0.888   0.765   0.714   0.998   0.844   0.775   0.904   0.694   0.567
219   Y         0.178   0.093  -0.040   0.369   0.245   0.061   0.145   0.015  -0.185
220   P         0.888   0.765   0.714   1.017   0.852   0.772   0.904   0.694   0.567
221   Y        -0.479  -0.578  -0.644  -0.301  -0.475  -0.566  -0.463  -0.588  -0.651
222   G         0.178   0.035  -0.061   0.303   0.097  -0.061   0.145  -0.066  -0.216
223   I        -0.115  -0.199  -0.153  -0.259  -0.379  -0.338  -0.311  -0.416  -0.360
224   Y        -1.207  -1.207  -1.139  -1.052  -1.048  -0.966  -1.070  -1.062  -0.950
225   E         1.642   1.665   1.759   1.494   1.529   1.676   1.815   1.849   1.999
226   T         0.888   0.765   0.714   1.037   0.880   0.821   0.904   0.694   0.567
227   V         0.178   0.178  -0.016   0.157   0.154  -0.146   0.145   0.144  -0.148
228   L        -0.705  -0.679  -0.690  -0.870  -0.813  -0.852  -0.766  -0.725  -0.711
229   K         0.888   0.765   0.714   0.974   0.810   0.728   0.904   0.694   0.567
230   E         1.642   1.665   1.759   1.494   1.529   1.676   1.815   1.849   1.999
231   S        -0.115  -0.173  -0.137   0.082   0.001   0.034  -0.311  -0.376  -0.334
232   M        -1.571  -1.568  -1.488  -1.298  -1.308  -1.205  -1.222  -1.212  -1.090
233   E         1.642   1.665   1.759   1.494   1.529   1.676   1.815   1.849   1.999
234   E         1.642   1.665   1.759   1.494   1.529   1.676   1.815   1.849   1.999
235   A         1.642   1.665   1.759   1.716   1.732   1.896   1.815   1.849   1.999
236   N        -0.705  -0.736  -0.706  -0.680  -0.716  -0.670  -0.766  -0.791  -0.728
237   L         1.642   1.665   1.759   1.506   1.538   1.688   1.815   1.849   1.999
238   E        -0.705  -0.670  -0.685  -0.847  -0.796  -0.798  -0.766  -0.733  -0.708
239   K        -0.705  -0.677  -0.690  -0.853  -0.810  -0.805  -0.766  -0.724  -0.710
240   S        -0.843  -0.871  -0.739  -0.958  -0.964  -0.780  -0.918  -0.933  -0.767
241   V        -1.207  -1.241  -1.149  -1.236  -1.280  -1.139  -1.070  -1.090  -0.958
242   I         0.387   0.427   0.512   0.031   0.097   0.224  -0.007   0.061   0.173
243   E        -1.069  -1.060  -1.090  -1.004  -0.994  -1.005  -0.918  -0.909  -0.900
244   D        -1.207  -1.226  -1.147  -1.126  -1.143  -1.027  -1.070  -1.078  -0.956
245   N        -0.115  -0.086  -0.125  -0.007   0.049  -0.015  -0.311  -0.256  -0.316
246   I        -0.479  -0.562  -0.642  -0.426  -0.562  -0.726  -0.463  -0.569  -0.648
247   K        -0.115  -0.101  -0.129  -0.144  -0.112  -0.164  -0.311  -0.281  -0.328
248   A        -0.115  -0.173  -0.137  -0.143  -0.241  -0.203  -0.311  -0.376  -0.334
249   T        -0.705  -0.670  -0.685  -0.771  -0.754  -0.745  -0.766  -0.733  -0.708
250   G         0.888   0.765   0.714   1.007   0.856   0.792   0.904   0.694   0.567
251   S        -0.115  -0.171  -0.136  -0.260  -0.333  -0.283  -0.311  -0.372  -0.334
252   V         0.888   0.765   0.714   0.844   0.673   0.588   0.904   0.694   0.567
253   S         0.178   0.112  -0.038   0.321   0.223  -0.038   0.145   0.041  -0.182
254   Y         1.642   1.665   1.759   1.688   1.725   1.868   1.815   1.849   1.999
255   L        -0.705  -0.663  -0.687  -0.811  -0.763  -0.747  -0.766  -0.725  -0.710
256   Y         0.542   0.601   0.568   0.483   0.584   0.492   0.297   0.399   0.284
257   F        -1.069  -1.096  -1.114  -1.008  -1.052  -1.136  -0.918  -0.946  -0.923
258   T        -0.705  -0.681  -0.673  -0.630  -0.598  -0.561  -0.766  -0.728  -0.693
259   G        -1.207  -1.231  -1.137  -1.166  -1.198  -1.051  -1.070  -1.082  -0.949
260   D        -0.115  -0.178  -0.143  -0.207  -0.306  -0.283  -0.311  -0.383  -0.347
261   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
262   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
263   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
264   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
265   K        -0.807  -0.757  -0.721  -0.812  -0.733  -0.692  -0.863  -0.803  -0.741
266   F        -0.105  -0.195  -0.166  -0.124  -0.289  -0.277  -0.268  -0.402  -0.371
267   N        -1.316  -1.286  -1.179  -1.343  -1.287  -1.139  -1.161  -1.125  -0.983
268   K        -1.316  -1.286  -1.179  -1.213  -1.173  -1.009  -1.161  -1.125  -0.983
269   E         0.814   0.844   0.710   0.737   0.781   0.610   0.782   0.827   0.560
270   S        -0.642  -0.690  -0.699  -0.595  -0.680  -0.729  -0.665  -0.722  -0.715
271   D        -0.843  -0.809  -0.736  -0.906  -0.861  -0.738  -0.918  -0.878  -0.763
272   F        -1.571  -1.568  -1.488  -1.491  -1.534  -1.387  -1.222  -1.212  -1.090
273   I         0.542   0.618   0.603   0.373   0.507   0.440   0.297   0.429   0.354
274   V        -0.705  -0.736  -0.706  -0.630  -0.671  -0.642  -0.766  -0.791  -0.728
275   G         0.387   0.427   0.512   0.171   0.242   0.363  -0.007   0.061   0.173
276   E         1.642   1.665   1.759   1.494   1.529   1.676   1.815   1.849   1.999
277   V         0.888   0.765   0.714   0.892   0.738   0.684   0.904   0.694   0.567
278   Q         0.542   0.514   0.542   0.361   0.318   0.364   0.297   0.233   0.233
279   Y         0.888   0.765   0.714   1.039   0.888   0.820   0.904   0.694   0.567
280   V        -0.115  -0.047  -0.123  -0.248  -0.147  -0.274  -0.311  -0.221  -0.319
281   Y         0.178   0.183  -0.017   0.373   0.389   0.103   0.145   0.151  -0.150
282   D         1.642   1.665   1.759   1.669   1.700   1.849   1.815   1.849   1.999
283   L         0.178   0.271   0.006   0.117   0.247  -0.156   0.145   0.278  -0.116
284   K        -0.115  -0.031  -0.117  -0.316  -0.181  -0.307  -0.311  -0.183  -0.308
285   L        -0.204  -0.207  -0.166  -0.386  -0.385  -0.293  -0.463  -0.457  -0.385
286   S        -0.115  -0.096  -0.143  -0.141  -0.138  -0.188  -0.311  -0.306  -0.348
287   E        -1.571  -1.544  -1.475  -1.505  -1.471  -1.347  -1.222  -1.192  -1.080
288   D        -0.705  -0.674  -0.682  -0.782  -0.717  -0.721  -0.766  -0.718  -0.700
289   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
290   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
291   I        -0.705  -0.671  -0.673  -0.789  -0.731  -0.710  -0.766  -0.713  -0.693
292   I        -0.479  -0.517  -0.617  -0.442  -0.514  -0.705  -0.463  -0.514  -0.618
293   P         1.642   1.665   1.759   1.706   1.737   1.886   1.815   1.849   1.999
294   K        -1.571  -1.578  -1.482  -1.531  -1.573  -1.413  -1.222  -1.220  -1.085
295   P         1.642   1.665   1.759   1.692   1.724   1.872   1.815   1.849   1.999
296   N        -1.069  -1.096  -1.114  -0.861  -0.916  -0.954  -0.918  -0.946  -0.923
297   D         1.642   1.665   1.759   1.669   1.700   1.849   1.815   1.849   1.999
298   G         1.642   1.665   1.759   1.652   1.687   1.832   1.815   1.849   1.999
299   E         1.642   1.665   1.759   1.494   1.529   1.676   1.815   1.849   1.999
300   V         0.542   0.618   0.603   0.348   0.459   0.430   0.297   0.429   0.354
301   E         0.888   0.929   0.745   0.808   0.867   0.610   0.904   0.967   0.624
302   S        -0.115  -0.032  -0.104  -0.085   0.049  -0.046  -0.311  -0.186  -0.284
303   F         1.642   1.665   1.759   1.692   1.730   1.872   1.815   1.849   1.999
304   N        -1.571  -1.566  -1.492  -1.371  -1.376  -1.268  -1.222  -1.210  -1.093
305   L         0.888   0.935   0.747   0.815   0.879   0.614   0.904   0.976   0.628
306   F        -0.705  -0.722  -0.682  -0.716  -0.716  -0.626  -0.766  -0.776  -0.702
307   S        -0.705  -0.750  -0.697  -0.697  -0.765  -0.682  -0.766  -0.810  -0.720
308   L         0.387   0.427   0.512  -0.051   0.019   0.142  -0.007   0.061   0.173
309   Q        -0.705  -0.738  -0.708  -0.605  -0.683  -0.643  -0.766  -0.798  -0.731
310   E        -0.115  -0.098  -0.125  -0.222  -0.193  -0.213  -0.311  -0.276  -0.321
311   T        -0.115  -0.173  -0.137  -0.283  -0.363  -0.315  -0.311  -0.376  -0.334
312   I        -0.705  -0.736  -0.706  -0.858  -0.877  -0.834  -0.766  -0.791  -0.728
313   N        -1.069  -1.089  -1.089  -0.966  -1.006  -1.024  -0.918  -0.939  -0.900
314   A        -1.069  -1.096  -1.114  -0.873  -0.931  -0.962  -0.918  -0.946  -0.923
315   L         0.888   0.867   0.732   0.815   0.789   0.590   0.904   0.867   0.600
316   R        -1.571  -1.530  -1.475  -1.455  -1.404  -1.318  -1.222  -1.181  -1.080
317   K        -1.069  -1.106  -1.103  -0.860  -0.912  -0.934  -0.918  -0.956  -0.913
318   K        -0.341  -0.272  -0.225  -0.506  -0.385  -0.332  -0.614  -0.515  -0.456
319   E         0.178   0.035  -0.061   0.175  -0.012  -0.152   0.145  -0.066  -0.216
320   F         0.888   0.765   0.714   1.044   0.893   0.825   0.904   0.694   0.567
321   K         1.642   1.665   1.759   1.652   1.688   1.832   1.815   1.849   1.999
322   P         1.642   1.665   1.759   1.692   1.724   1.872   1.815   1.849   1.999
323   N         1.642   1.665   1.759   1.735   1.775   1.914   1.815   1.849   1.999
324   C         0.888   0.867   0.732   1.223   1.196   0.990   0.904   0.867   0.600
325   A         0.387   0.431   0.511   0.191   0.257   0.380  -0.007   0.069   0.171
326   L         0.888   0.765   0.714   0.798   0.619   0.526   0.904   0.694   0.567
327   V         0.387   0.399   0.496   0.052   0.063   0.204  -0.007   0.005   0.140
328   M        -0.479  -0.413  -0.609  -0.188  -0.088  -0.437  -0.463  -0.378  -0.609
329   V        -0.705  -0.706  -0.689  -0.929  -0.953  -0.904  -0.766  -0.770  -0.713
330   D         0.542   0.586   0.577   0.390   0.464   0.398   0.297   0.371   0.303
331   F         1.642   1.665   1.759   1.692   1.730   1.872   1.815   1.849   1.999
332   L         0.888   0.765   0.714   0.825   0.658   0.580   0.904   0.694   0.567
333   I         0.542   0.510   0.540   0.373   0.304   0.308   0.297   0.224   0.229
334   R         1.642   1.665   1.759   1.718   1.746   1.898   1.815   1.849   1.999
335   H         0.178   0.178  -0.016   0.503   0.504   0.204   0.145   0.144  -0.148
336   G         1.642   1.665   1.759   1.652   1.687   1.832   1.815   1.849   1.999
337   Y         0.178   0.035  -0.061   0.298   0.086  -0.103   0.145  -0.066  -0.216
338   I         0.888   0.765   0.714   0.953   0.790   0.701   0.904   0.694   0.567
339   T         0.178   0.178  -0.016   0.336   0.334   0.046   0.145   0.144  -0.148
340   P         0.178   0.178  -0.016   0.319   0.312   0.010   0.145   0.144  -0.148
341   E         1.642   1.665   1.759   1.494   1.529   1.676   1.815   1.849   1.999
342   N         0.047   0.103  -0.062   0.152   0.240  -0.038  -0.045   0.037  -0.218
343   E         0.178   0.203  -0.019   0.176   0.215  -0.087   0.145   0.179  -0.153
344   P         0.888   0.957   0.746   0.978   1.073   0.751   0.904   1.011   0.627
345   N         0.178   0.035  -0.061   0.409   0.220   0.059   0.145  -0.066  -0.216
346   Y         1.642   1.665   1.759   1.688   1.725   1.868   1.815   1.849   1.999
347   L        -0.479  -0.578  -0.644  -0.522  -0.683  -0.792  -0.463  -0.588  -0.651
348   E        -0.479  -0.582  -0.637  -0.496  -0.653  -0.731  -0.463  -0.593  -0.643
349   L         0.178   0.123  -0.027   0.252   0.175  -0.081   0.145   0.054  -0.165
350   V        -0.705  -0.782  -0.704  -0.881  -0.988  -0.876  -0.766  -0.839  -0.727
351   T        -1.069  -1.110  -1.101  -0.803  -0.867  -0.845  -0.918  -0.959  -0.911
352   R         0.888   0.867   0.732   1.063   1.036   0.863   0.904   0.867   0.600
353   M        -0.705  -0.770  -0.711  -0.416  -0.517  -0.429  -0.766  -0.824  -0.733
354   H         1.642   1.665   1.759   1.851   1.884   2.030   1.815   1.849   1.999
355   R         0.888   0.964   0.748   1.011   1.110   0.790   0.904   1.023   0.629
356   R        -1.935  -1.900  -1.793  -1.464  -1.416  -1.259  -1.374  -1.338  -1.196
357   L        -0.705  -0.734  -0.691  -0.746  -0.793  -0.714  -0.766  -0.787  -0.711
358   P         0.888   0.765   0.714   1.014   0.842   0.765   0.904   0.694   0.567
359   F         1.642   1.665   1.759   1.692   1.730   1.872   1.815   1.849   1.999
360   P         0.888   0.964   0.748   1.014   1.111   0.820   0.904   1.023   0.629
361   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
362   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
363   T        -0.807  -0.829  -0.747  -0.876  -0.916  -0.812  -0.863  -0.886  -0.770
364   L        -0.705  -0.731  -0.691  -0.738  -0.757  -0.661  -0.766  -0.783  -0.711
365   N        -1.207  -1.231  -1.139  -1.094  -1.133  -0.996  -1.070  -1.082  -0.950
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P47173
Output conservation file - output/P47173
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
