1     M         1.622   1.644   1.788   1.805   1.835   2.051   1.804   1.833   2.083
2     -        -0.419  -0.386  -0.448  -0.402  -0.358  -0.494  -0.487  -0.444  -0.532
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    P        -1.072  -1.080  -0.954  -1.111  -1.138  -0.956  -1.060  -1.054  -0.881
11    K        -0.980  -1.069  -0.937  -1.009  -1.117  -0.923  -0.965  -1.035  -0.866
12    F        -1.378  -1.298  -1.226  -1.301  -1.184  -1.082  -1.190  -1.108  -0.978
13    Y        -0.795  -0.734  -0.580  -0.937  -0.843  -0.633  -0.965  -0.884  -0.696
14    K        -0.783  -0.751  -0.852  -0.772  -0.737  -0.870  -0.741  -0.710  -0.775
15    L         1.622   1.644   1.788   1.412   1.449   1.669   1.804   1.833   2.083
16    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
19    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
20    S        -0.887  -0.886  -0.866  -0.850  -0.852  -0.802  -0.890  -0.876  -0.799
21    N        -0.490  -0.428  -0.466  -0.555  -0.468  -0.491  -0.666  -0.590  -0.577
22    G         1.622   1.644   1.788   1.580   1.610   1.832   1.804   1.833   2.083
23    F        -1.961  -1.871  -1.764  -1.710  -1.611  -1.411  -1.414  -1.334  -1.170
24    K        -1.378  -1.360  -1.247  -1.431  -1.398  -1.238  -1.190  -1.156  -0.994
25    I         1.047   0.990   0.867   1.139   1.078   0.937   1.131   1.036   0.777
26    P         1.047   1.116   0.877   1.164   1.254   0.938   1.131   1.231   0.796
27    S        -1.225  -1.288  -1.240  -1.081  -1.174  -1.118  -1.040  -1.092  -0.986
28    I        -0.304  -0.219  -0.401  -0.249  -0.106  -0.409  -0.366  -0.244  -0.478
29    A         0.033   0.026   0.029  -0.096  -0.083  -0.088  -0.217  -0.206  -0.220
30    L         0.491   0.358   0.165   0.468   0.317   0.061   0.532   0.337   0.014
31    G         1.622   1.644   1.788   1.580   1.610   1.832   1.804   1.833   2.083
32    T        -1.378  -1.441  -1.275  -1.299  -1.411  -1.191  -1.190  -1.215  -1.014
33    Y         1.047   0.981   0.861   1.187   1.118   0.967   1.131   1.021   0.764
34    D        -0.887  -0.859  -0.893  -0.763  -0.705  -0.745  -0.890  -0.857  -0.825
35    I        -0.980  -1.059  -0.936  -1.053  -1.171  -1.007  -0.965  -1.026  -0.864
36    P        -0.683  -0.896  -0.895  -0.467  -0.791  -0.860  -0.598  -0.834  -0.817
37    R        -1.345  -1.366  -1.241  -1.149  -1.183  -1.025  -1.153  -1.151  -0.985
38    S        -0.887  -0.929  -0.866  -0.828  -0.851  -0.772  -0.890  -0.899  -0.794
39    Q        -1.040  -0.953  -0.904  -1.210  -1.078  -0.988  -1.040  -0.944  -0.836
40    T         0.737   0.659   0.687   0.788   0.673   0.691   0.607   0.450   0.415
41    A        -1.345  -1.352  -1.259  -1.262  -1.260  -1.140  -1.153  -1.148  -1.001
42    E        -1.993  -1.925  -1.774  -1.869  -1.774  -1.567  -1.430  -1.365  -1.175
43    I        -1.133  -1.130  -0.953  -1.359  -1.360  -1.115  -1.115  -1.092  -0.881
44    V         1.622   1.644   1.788   1.581   1.612   1.833   1.804   1.833   2.083
45    Y        -0.887  -0.833  -0.853  -0.733  -0.672  -0.637  -0.890  -0.832  -0.788
46    E        -0.304  -0.408  -0.466  -0.226  -0.347  -0.443  -0.366  -0.486  -0.565
47    G         1.047   1.154   0.881   1.089   1.212   0.872   1.131   1.287   0.803
48    V         0.203   0.360   0.113   0.091   0.302  -0.022   0.083   0.309  -0.074
49    K        -1.225  -1.277  -1.213  -1.159  -1.222  -1.142  -1.040  -1.077  -0.964
50    C        -1.378  -1.396  -1.247  -1.310  -1.340  -1.182  -1.190  -1.179  -0.993
51    G         1.622   1.644   1.788   1.580   1.610   1.832   1.804   1.833   2.083
52    Y         1.622   1.644   1.788   1.655   1.688   1.905   1.804   1.833   2.083
53    R         1.622   1.644   1.788   1.716   1.743   1.965   1.804   1.833   2.083
54    H         0.203   0.139   0.071   0.338   0.240   0.072   0.083  -0.011  -0.140
55    F         0.203   0.122   0.057   0.392   0.244   0.116   0.083  -0.057  -0.169
56    D         1.622   1.644   1.788   1.604   1.629   1.855   1.804   1.833   2.083
57    T         0.737   0.671   0.693   0.734   0.621   0.605   0.607   0.473   0.427
58    A         1.622   1.644   1.788   1.580   1.606   1.832   1.804   1.833   2.083
59    V        -0.445  -0.531  -0.497  -0.457  -0.567  -0.502  -0.591  -0.685  -0.610
60    L        -0.783  -0.937  -0.907  -0.818  -1.002  -0.931  -0.741  -0.895  -0.832
61    Y         1.622   1.644   1.788   1.655   1.688   1.905   1.804   1.833   2.083
62    G        -0.042  -0.176  -0.372   0.173   0.011  -0.261   0.008  -0.166  -0.433
63    N         1.622   1.644   1.788   1.678   1.712   1.928   1.804   1.833   2.083
64    E         1.622   1.644   1.788   1.554   1.593   1.806   1.804   1.833   2.083
65    K        -1.716  -1.668  -1.526  -1.604  -1.535  -1.354  -1.339  -1.284  -1.096
66    E        -0.304  -0.417  -0.467  -0.294  -0.458  -0.565  -0.366  -0.511  -0.568
67    V        -0.537  -0.636  -0.547  -0.528  -0.665  -0.539  -0.666  -0.782  -0.661
68    G        -0.042  -0.021  -0.351   0.152   0.182  -0.273   0.008   0.036  -0.405
69    D        -0.980  -0.930  -0.911  -0.918  -0.881  -0.856  -0.965  -0.928  -0.842
70    G         0.541   0.487   0.611   0.331   0.213   0.373   0.232   0.107   0.252
71    I         1.622   1.644   1.788   1.604   1.632   1.855   1.804   1.833   2.083
72    I        -0.980  -0.900  -0.914  -1.133  -1.066  -1.080  -0.965  -0.897  -0.845
73    K        -1.028  -1.049  -1.155  -0.864  -0.903  -1.070  -0.815  -0.833  -0.905
74    W         0.431   0.437   0.595   0.417   0.416   0.638   0.008   0.005   0.219
75    L        -0.042  -0.097  -0.358   0.018  -0.035  -0.363   0.008  -0.070  -0.414
76    N        -1.040  -1.032  -0.934  -1.133  -1.134  -0.972  -1.040  -1.018  -0.863
77    E         0.033  -0.030   0.017  -0.147  -0.235  -0.192  -0.217  -0.297  -0.245
78    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
79    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
80    D        -0.069   0.101   0.017  -0.128   0.154  -0.015  -0.334  -0.070  -0.224
81    P        -0.069  -0.097  -0.019  -0.214  -0.224  -0.170  -0.334  -0.353  -0.281
82    G        -0.637  -0.607  -0.532  -0.737  -0.698  -0.590  -0.793  -0.761  -0.646
83    N        -0.887  -0.751  -0.846  -0.822  -0.668  -0.749  -0.890  -0.764  -0.782
84    H        -1.471  -1.424  -1.270  -1.410  -1.364  -1.154  -1.265  -1.206  -1.012
85    K        -0.042  -0.049  -0.342   0.078   0.077  -0.329   0.008  -0.003  -0.393
86    R         1.622   1.644   1.788   1.716   1.743   1.965   1.804   1.833   2.083
87    E        -1.225  -1.227  -1.199  -1.163  -1.151  -1.138  -1.040  -1.022  -0.948
88    E         0.431   0.490   0.618   0.121   0.231   0.392   0.008   0.115   0.267
89    I         0.033   0.071   0.027  -0.072  -0.045  -0.064  -0.217  -0.186  -0.229
90    F         0.033  -0.017   0.020   0.196   0.128   0.187  -0.217  -0.283  -0.242
91    Y         0.203   0.073   0.034   0.296   0.105   0.003   0.083  -0.116  -0.203
92    T         1.047   1.034   0.873   1.183   1.175   0.986   1.131   1.106   0.788
93    T         0.541   0.487   0.611   0.399   0.276   0.433   0.232   0.107   0.252
94    K         1.622   1.644   1.788   1.507   1.543   1.761   1.804   1.833   2.083
95    L         1.047   1.034   0.873   0.924   0.919   0.706   1.131   1.106   0.788
96    W        -0.783  -0.937  -0.907  -0.474  -0.705  -0.701  -0.741  -0.895  -0.832
97    N         0.396   0.427   0.596   0.130   0.175   0.425  -0.067  -0.017   0.220
98    S        -0.980  -1.069  -0.937  -0.990  -1.121  -0.932  -0.965  -1.035  -0.866
99    Q        -0.445  -0.493  -0.500  -0.391  -0.487  -0.467  -0.591  -0.650  -0.613
100   N        -1.444  -1.390  -1.287  -1.339  -1.275  -1.116  -1.236  -1.175  -1.023
101   G         0.491   0.369   0.161   0.616   0.466   0.162   0.532   0.353   0.007
102   Y         1.047   1.120   0.879   1.172   1.264   0.959   1.131   1.237   0.799
103   K        -1.623  -1.581  -1.506  -1.515  -1.458  -1.339  -1.265  -1.216  -1.082
104   R        -1.623  -1.488  -1.498  -1.520  -1.347  -1.352  -1.265  -1.146  -1.074
105   A        -0.047  -0.028   0.017  -0.224  -0.154  -0.091  -0.366  -0.303  -0.237
106   K        -0.304  -0.426  -0.470  -0.294  -0.471  -0.533  -0.366  -0.528  -0.570
107   A        -0.980  -0.880  -0.892  -0.982  -0.872  -0.862  -0.965  -0.870  -0.824
108   A        -0.783  -0.817  -0.871  -0.738  -0.820  -0.912  -0.741  -0.785  -0.799
109   I         0.491   0.464   0.176   0.625   0.593   0.173   0.532   0.491   0.032
110   R        -1.225  -1.189  -0.983  -1.394  -1.333  -1.041  -1.190  -1.140  -0.905
111   Q        -1.961  -1.885  -1.757  -1.869  -1.778  -1.590  -1.414  -1.344  -1.166
112   C        -0.887  -0.872  -0.895  -0.681  -0.704  -0.687  -0.890  -0.867  -0.827
113   L        -0.059  -0.039  -0.023  -0.281  -0.264  -0.237  -0.292  -0.270  -0.282
114   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
115   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
116   N        -0.637  -0.510  -0.542  -0.716  -0.520  -0.594  -0.793  -0.626  -0.653
117   E        -0.783  -0.727  -0.819  -0.726  -0.611  -0.740  -0.741  -0.656  -0.739
118   V        -0.304  -0.429  -0.469  -0.257  -0.447  -0.520  -0.366  -0.530  -0.568
119   S        -1.285  -1.274  -1.224  -1.282  -1.268  -1.196  -1.115  -1.089  -0.974
120   G         0.541   0.636   0.673   0.341   0.500   0.511   0.232   0.405   0.384
121   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
122   L         1.005   0.999   0.843   0.870   0.873   0.656   1.065   1.050   0.729
123   Q        -0.980  -0.948  -0.898  -0.981  -0.930  -0.866  -0.965  -0.917  -0.825
124   Y         1.622   1.644   1.788   1.655   1.688   1.905   1.804   1.833   2.083
125   I         1.622   1.644   1.788   1.604   1.632   1.855   1.804   1.833   2.083
126   D         1.622   1.644   1.788   1.604   1.629   1.855   1.804   1.833   2.083
127   L         0.541   0.599   0.648   0.269   0.361   0.427   0.232   0.333   0.332
128   L         0.541   0.487   0.611   0.258   0.175   0.364   0.232   0.107   0.252
129   L         1.047   1.034   0.873   0.924   0.919   0.706   1.131   1.106   0.788
130   I         0.737   0.671   0.693   0.648   0.527   0.488   0.607   0.473   0.427
131   H         1.047   0.981   0.861   1.300   1.227   1.061   1.131   1.021   0.764
132   S         0.737   0.727   0.735   0.674   0.643   0.626   0.607   0.577   0.512
133   P         1.622   1.644   1.788   1.655   1.690   1.905   1.804   1.833   2.083
134   L        -0.304  -0.417  -0.467  -0.385  -0.538  -0.592  -0.366  -0.511  -0.568
135   E        -1.225  -1.082  -1.181  -1.090  -0.887  -1.025  -1.040  -0.888  -0.935
136   G         0.412   0.372   0.134   0.493   0.444   0.059   0.418   0.358  -0.034
137   S        -1.072  -1.037  -0.928  -1.145  -1.087  -0.915  -1.060  -1.012  -0.859
138   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
139   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
140   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
141   K        -0.527  -0.405  -0.480  -0.699  -0.529  -0.596  -0.691  -0.553  -0.588
142   L        -1.961  -1.931  -1.784  -1.956  -1.890  -1.710  -1.414  -1.371  -1.182
143   R         1.622   1.644   1.788   1.716   1.743   1.965   1.804   1.833   2.083
144   L         0.203   0.108   0.052   0.064  -0.077  -0.139   0.083  -0.076  -0.176
145   E        -0.783  -0.837  -0.874  -0.743  -0.832  -0.902  -0.741  -0.802  -0.803
146   T        -0.490  -0.480  -0.476  -0.582  -0.561  -0.538  -0.666  -0.629  -0.583
147   W         1.047   1.143   0.878   1.321   1.438   1.099   1.131   1.270   0.796
148   R         0.491   0.664   0.209   0.542   0.755   0.167   0.532   0.773   0.083
149   A         1.047   1.120   0.879   1.089   1.175   0.869   1.131   1.237   0.799
150   M        -0.490  -0.471  -0.478  -0.548  -0.536  -0.492  -0.666  -0.632  -0.590
151   Q        -0.445  -0.493  -0.500  -0.431  -0.525  -0.530  -0.591  -0.650  -0.613
152   E         0.203   0.146   0.055   0.160   0.090  -0.105   0.083   0.004  -0.173
153   A        -0.304  -0.414  -0.467  -0.240  -0.404  -0.509  -0.366  -0.509  -0.567
154   V         1.622   1.644   1.788   1.581   1.612   1.833   1.804   1.833   2.083
155   D         0.203   0.149   0.059   0.182   0.101  -0.105   0.083   0.006  -0.166
156   E        -1.225  -1.253  -1.214  -1.208  -1.247  -1.232  -1.040  -1.052  -0.964
157   G         1.622   1.644   1.788   1.580   1.610   1.832   1.804   1.833   2.083
158   L        -1.623  -1.584  -1.491  -1.665  -1.588  -1.462  -1.265  -1.212  -1.069
159   V        -0.047  -0.083   0.000  -0.290  -0.335  -0.219  -0.366  -0.398  -0.272
160   K         0.396   0.429   0.596   0.089   0.157   0.399  -0.067  -0.014   0.220
161   S        -0.783  -0.847  -0.852  -0.634  -0.710  -0.722  -0.741  -0.787  -0.775
162   I        -0.042  -0.184  -0.377   0.116  -0.078  -0.423   0.008  -0.176  -0.439
163   G         1.047   1.034   0.873   1.089   1.078   0.860   1.131   1.106   0.788
164   V         1.622   1.644   1.788   1.581   1.612   1.833   1.804   1.833   2.083
165   S         1.622   1.644   1.788   1.589   1.609   1.840   1.804   1.833   2.083
166   N         1.622   1.644   1.788   1.678   1.712   1.928   1.804   1.833   2.083
167   Y         1.047   0.990   0.867   1.187   1.128   0.977   1.131   1.036   0.777
168   G         1.622   1.644   1.788   1.580   1.610   1.832   1.804   1.833   2.083
169   K        -0.490  -0.448  -0.481  -0.639  -0.561  -0.546  -0.666  -0.603  -0.590
170   K        -0.047   0.045   0.020  -0.188  -0.074  -0.050  -0.366  -0.250  -0.243
171   H         1.622   1.644   1.788   1.777   1.807   2.024   1.804   1.833   2.083
172   I         0.431   0.428   0.593   0.041   0.004   0.236   0.008  -0.015   0.213
173   D        -0.735  -0.760  -0.591  -0.933  -0.963  -0.736  -0.890  -0.914  -0.709
174   E         1.047   1.116   0.877   1.077   1.170   0.877   1.131   1.231   0.796
175   L         0.203   0.139   0.071   0.083   0.004  -0.096   0.083  -0.011  -0.140
176   L        -0.304  -0.428  -0.466  -0.316  -0.456  -0.482  -0.366  -0.514  -0.559
177   N        -1.345  -1.289  -1.241  -1.337  -1.253  -1.235  -1.153  -1.080  -0.985
178   W        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
179   P        -1.378  -1.237  -1.243  -1.384  -1.209  -1.189  -1.190  -1.064  -0.990
180   E        -1.716  -1.678  -1.537  -1.611  -1.520  -1.348  -1.339  -1.291  -1.103
181   L        -1.225  -1.278  -1.242  -1.229  -1.282  -1.209  -1.040  -1.085  -0.988
182   K         1.047   1.120   0.879   1.024   1.118   0.818   1.131   1.237   0.799
183   H        -0.445  -0.441  -0.474  -0.395  -0.406  -0.395  -0.591  -0.593  -0.584
184   K        -0.304  -0.366  -0.433  -0.310  -0.367  -0.494  -0.366  -0.421  -0.518
185   P         1.622   1.644   1.788   1.655   1.690   1.905   1.804   1.833   2.083
186   V        -0.537  -0.581  -0.526  -0.582  -0.638  -0.593  -0.666  -0.713  -0.636
187   V         0.737   0.727   0.735   0.626   0.604   0.554   0.607   0.577   0.512
188   N         1.622   1.644   1.788   1.678   1.712   1.928   1.804   1.833   2.083
189   Q         1.622   1.644   1.788   1.707   1.741   1.956   1.804   1.833   2.083
190   I         1.047   1.051   0.876   1.113   1.122   0.888   1.131   1.133   0.794
191   E         1.622   1.644   1.788   1.554   1.593   1.806   1.804   1.833   2.083
192   I        -0.537  -0.636  -0.547  -0.631  -0.812  -0.684  -0.666  -0.782  -0.661
193   S         0.541   0.487   0.611   0.421   0.316   0.500   0.232   0.107   0.252
194   P         1.622   1.644   1.788   1.655   1.690   1.905   1.804   1.833   2.083
195   W         0.541   0.487   0.611   0.620   0.512   0.669   0.232   0.107   0.252
196   I        -0.887  -0.823  -0.876  -0.726  -0.665  -0.746  -0.890  -0.829  -0.809
197   M        -0.537  -0.636  -0.547  -0.417  -0.603  -0.506  -0.666  -0.782  -0.661
198   R         0.033  -0.029  -0.001   0.097  -0.011   0.055  -0.217  -0.322  -0.270
199   Q         0.491   0.369   0.161   0.741   0.593   0.271   0.532   0.353   0.007
200   E        -0.047  -0.083   0.000  -0.297  -0.333  -0.211  -0.366  -0.398  -0.272
201   L        -0.047  -0.082  -0.007  -0.401  -0.414  -0.286  -0.366  -0.396  -0.279
202   A        -0.537  -0.636  -0.547  -0.540  -0.693  -0.554  -0.666  -0.782  -0.661
203   D        -0.550  -0.572  -0.801  -0.321  -0.367  -0.716  -0.441  -0.467  -0.716
204   Y        -0.537  -0.497  -0.488  -0.417  -0.349  -0.352  -0.666  -0.594  -0.590
205   C         1.622   1.644   1.788   1.807   1.836   2.053   1.804   1.833   2.083
206   K        -0.980  -1.033  -0.923  -1.157  -1.204  -1.062  -0.965  -1.003  -0.851
207   S        -0.304  -0.271  -0.422  -0.278  -0.241  -0.481  -0.366  -0.322  -0.510
208   K        -0.887  -0.836  -0.880  -0.838  -0.756  -0.788  -0.890  -0.839  -0.813
209   G        -0.200  -0.198  -0.078  -0.394  -0.392  -0.237  -0.516  -0.507  -0.369
210   L        -0.059   0.066   0.018  -0.226  -0.014  -0.167  -0.292  -0.104  -0.222
211   V        -1.471  -1.450  -1.464  -1.227  -1.200  -1.255  -1.115  -1.087  -1.045
212   V         0.203   0.076   0.030   0.174  -0.027  -0.154   0.083  -0.114  -0.211
213   E         1.047   0.990   0.867   1.063   1.006   0.825   1.131   1.036   0.777
214   A         0.737   0.727   0.735   0.697   0.677   0.669   0.607   0.577   0.512
215   F         1.047   1.154   0.881   1.187   1.311   0.998   1.131   1.287   0.803
216   A         0.541   0.514   0.625   0.335   0.265   0.409   0.232   0.164   0.283
217   P         1.622   1.644   1.788   1.655   1.690   1.905   1.804   1.833   2.083
218   L         1.047   1.147   0.880   0.947   1.068   0.774   1.131   1.277   0.801
219   C        -0.980  -1.003  -0.910  -0.894  -0.922  -0.807  -0.965  -0.966  -0.842
220   H         0.541   0.521   0.626   0.570   0.523   0.642   0.232   0.178   0.284
221   G         1.622   1.644   1.788   1.580   1.610   1.832   1.804   1.833   2.083
222   Y        -1.623  -1.673  -1.527  -1.397  -1.465  -1.282  -1.265  -1.283  -1.096
223   K         0.541   0.504   0.613   0.319   0.255   0.402   0.232   0.143   0.258
224   M        -0.304  -0.279  -0.102  -0.521  -0.473  -0.212  -0.666  -0.628  -0.404
225   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
226   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
227   T        -1.285  -1.245  -1.197  -1.254  -1.201  -1.127  -1.115  -1.066  -0.953
228   N        -0.795  -0.779  -0.588  -0.902  -0.874  -0.600  -0.965  -0.936  -0.707
229   P        -0.042  -0.120  -0.362   0.187   0.082  -0.309   0.008  -0.098  -0.419
230   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
231   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
232   D        -1.378  -1.408  -1.253  -1.418  -1.434  -1.240  -1.190  -1.183  -0.996
233   L        -0.059  -0.011   0.003  -0.289  -0.221  -0.208  -0.292  -0.223  -0.242
234   L        -1.040  -1.002  -0.909  -1.180  -1.126  -0.957  -1.040  -0.991  -0.843
235   K        -1.133  -1.121  -0.956  -1.326  -1.293  -1.063  -1.115  -1.087  -0.883
236   V        -0.200  -0.176  -0.051  -0.489  -0.452  -0.305  -0.516  -0.477  -0.329
237   C        -0.550  -0.308  -0.756  -0.314  -0.013  -0.610  -0.441  -0.150  -0.664
238   K        -1.028  -0.948  -1.133  -0.864  -0.757  -1.037  -0.815  -0.726  -0.883
239   E         0.541   0.665   0.702   0.252   0.473   0.479   0.232   0.462   0.445
240   V        -0.304  -0.205  -0.407  -0.221  -0.068  -0.412  -0.366  -0.222  -0.483
241   D        -0.887  -0.774  -0.849  -0.846  -0.680  -0.781  -0.890  -0.765  -0.782
242   R        -1.225  -1.103  -1.192  -1.091  -0.957  -1.009  -1.040  -0.923  -0.946
243   N        -0.795  -0.699  -0.570  -0.953  -0.820  -0.635  -0.965  -0.854  -0.687
244   P        -0.783  -0.753  -0.851  -0.626  -0.592  -0.751  -0.741  -0.706  -0.779
245   G         0.541   0.665   0.702   0.331   0.540   0.556   0.232   0.462   0.445
246   Q         1.622   1.644   1.788   1.707   1.741   1.956   1.804   1.833   2.083
247   V        -0.642  -0.561  -0.531  -0.919  -0.800  -0.760  -0.815  -0.723  -0.648
248   L         1.047   0.990   0.867   0.947   0.895   0.756   1.131   1.036   0.777
249   I         1.047   1.002   0.863   1.113   1.061   0.867   1.131   1.055   0.769
250   R         0.737   0.822   0.748   0.782   0.911   0.742   0.607   0.751   0.539
251   W         1.047   0.990   0.867   1.321   1.260   1.082   1.131   1.036   0.777
252   S         0.491   0.407   0.184   0.639   0.532   0.238   0.532   0.408   0.044
253   L         0.491   0.418   0.180   0.435   0.352   0.006   0.532   0.424   0.037
254   Q         0.737   0.727   0.735   0.797   0.779   0.744   0.607   0.577   0.512
255   H         0.033   0.021   0.030  -0.068  -0.060  -0.036  -0.217  -0.210  -0.218
256   G         1.622   1.644   1.788   1.580   1.610   1.832   1.804   1.833   2.083
257   Y        -0.059  -0.127  -0.040   0.007  -0.095   0.019  -0.292  -0.398  -0.310
258   L        -0.047  -0.059   0.007  -0.369  -0.357  -0.257  -0.366  -0.360  -0.259
259   P         0.491   0.377   0.165   0.685   0.548   0.221   0.532   0.365   0.014
260   L         0.541   0.514   0.625   0.182   0.132   0.277   0.232   0.164   0.283
261   P         1.047   0.981   0.861   1.167   1.095   0.918   1.131   1.021   0.764
262   K         1.622   1.644   1.788   1.507   1.543   1.761   1.804   1.833   2.083
263   T         0.431   0.424   0.592   0.179   0.137   0.389   0.008  -0.023   0.212
264   K        -0.980  -1.007  -0.936  -1.049  -1.100  -0.965  -0.965  -0.992  -0.864
265   T        -0.783  -0.801  -0.875  -0.654  -0.711  -0.822  -0.741  -0.772  -0.804
266   V        -0.244  -0.255  -0.085  -0.515  -0.529  -0.298  -0.591  -0.596  -0.380
267   K        -1.716  -1.679  -1.536  -1.676  -1.603  -1.414  -1.339  -1.289  -1.103
268   R         1.047   0.981   0.861   1.248   1.173   1.024   1.131   1.021   0.764
269   L        -0.042  -0.194  -0.374   0.003  -0.176  -0.416   0.008  -0.189  -0.435
270   E        -1.225  -1.200  -1.191  -1.287  -1.243  -1.282  -1.040  -0.994  -0.941
271   G        -0.445  -0.392  -0.455  -0.537  -0.487  -0.543  -0.591  -0.541  -0.562
272   N         1.047   0.981   0.861   1.191   1.117   0.940   1.131   1.021   0.764
273   L        -0.304  -0.354  -0.443  -0.441  -0.523  -0.657  -0.366  -0.439  -0.537
274   A         0.412   0.533   0.180   0.520   0.671   0.175   0.418   0.589   0.038
275   A         0.491   0.639   0.209   0.611   0.790   0.224   0.532   0.737   0.083
276   Y        -0.783  -0.660  -0.826  -0.544  -0.352  -0.665  -0.741  -0.581  -0.745
277   N        -0.445  -0.399  -0.461  -0.445  -0.377  -0.442  -0.591  -0.527  -0.566
278   F         1.047   1.147   0.880   1.311   1.421   1.113   1.131   1.277   0.801
279   E        -0.304  -0.347  -0.447  -0.301  -0.335  -0.532  -0.366  -0.406  -0.541
280   L         0.203   0.201   0.060   0.063   0.027  -0.129   0.083   0.039  -0.164
281   S        -0.304  -0.405  -0.463  -0.199  -0.336  -0.471  -0.366  -0.481  -0.561
282   D        -1.623  -1.571  -1.506  -1.540  -1.470  -1.413  -1.265  -1.211  -1.079
283   E        -0.047  -0.033   0.009  -0.264  -0.232  -0.139  -0.366  -0.340  -0.261
284   Q        -0.642  -0.672  -0.544  -0.772  -0.805  -0.633  -0.815  -0.825  -0.659
285   M        -0.047   0.010   0.009  -0.092  -0.030  -0.003  -0.366  -0.302  -0.261
286   K        -1.285  -1.241  -1.217  -1.315  -1.220  -1.184  -1.115  -1.057  -0.967
287   F        -1.961  -1.858  -1.762  -1.789  -1.686  -1.501  -1.414  -1.327  -1.169
288   L         0.203   0.354   0.109   0.064   0.270  -0.044   0.083   0.302  -0.080
289   D        -0.304  -0.437  -0.460  -0.201  -0.386  -0.437  -0.366  -0.525  -0.552
290   H        -1.716  -1.716  -1.551  -1.511  -1.523  -1.311  -1.339  -1.314  -1.113
291   P        -0.047  -0.088  -0.011  -0.292  -0.349  -0.209  -0.366  -0.403  -0.285
292   D        -0.042   0.100  -0.317   0.161   0.337  -0.230   0.008   0.192  -0.360
293   A        -0.200  -0.230  -0.079  -0.464  -0.535  -0.322  -0.516  -0.565  -0.372
294   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
295   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
296   Y        -0.042  -0.221  -0.401   0.212  -0.018  -0.319   0.008  -0.223  -0.471
297   E        -1.378  -1.421  -1.257  -1.491  -1.551  -1.322  -1.190  -1.201  -1.001
298   P        -1.028  -1.200  -1.219  -0.666  -0.902  -0.954  -0.815  -0.981  -0.964
299   T        -0.042  -0.134  -0.370   0.172   0.049  -0.345   0.008  -0.111  -0.431
300   D         0.203   0.121   0.066   0.215   0.099  -0.013   0.083  -0.035  -0.148
301   W         1.047   0.981   0.861   1.321   1.249   1.072   1.131   1.021   0.764
302   E        -0.047  -0.082  -0.007  -0.269  -0.294  -0.164  -0.366  -0.396  -0.279
303   C         0.396   0.444   0.607   0.260   0.331   0.563  -0.067   0.020   0.244
304   T         1.047   0.990   0.867   1.183   1.124   0.978   1.131   1.036   0.777
305   D        -0.244  -0.167  -0.070  -0.491  -0.379  -0.235  -0.591  -0.485  -0.360
306   A        -0.042  -0.179  -0.367   0.160  -0.017  -0.283   0.008  -0.170  -0.427
307   P         0.203   0.128   0.053   0.259   0.134  -0.020   0.083  -0.047  -0.175
308   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P47137
Output conservation file - output/P47137
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
