1     M         1.659   1.669   1.677   2.002   2.016   2.031   1.769   1.779   1.791
2     S         1.659   1.669   1.677   1.526   1.520   1.556   1.769   1.779   1.791
3     E        -0.003  -0.055  -0.059  -0.244  -0.348  -0.342  -0.103  -0.182  -0.189
4     D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     R         1.659   1.669   1.677   1.752   1.776   1.781   1.769   1.779   1.791
7     V        -0.003   0.016  -0.035   0.228   0.269   0.174  -0.103  -0.072  -0.152
8     I        -0.003   0.057  -0.018   0.228   0.334   0.204  -0.103  -0.009  -0.125
9     S         1.659   1.669   1.677   1.526   1.520   1.556   1.769   1.779   1.791
10    Q        -1.211  -1.200  -1.191  -1.220  -1.195  -1.187  -1.039  -1.021  -1.005
11    P        -0.003  -0.055  -0.059  -0.088  -0.176  -0.197  -0.103  -0.182  -0.189
12    I        -0.003  -0.055  -0.059   0.163   0.092   0.069  -0.103  -0.182  -0.189
13    E        -0.003  -0.055  -0.059  -0.108  -0.196  -0.182  -0.103  -0.182  -0.189
14    L         1.659   1.669   1.677   1.623   1.638   1.652   1.769   1.779   1.791
15    H        -0.003  -0.055  -0.059   0.383   0.311   0.298  -0.103  -0.182  -0.189
16    K        -0.003  -0.055  -0.059  -0.096  -0.164  -0.181  -0.103  -0.182  -0.189
17    L         1.659   1.669   1.677   1.623   1.638   1.652   1.769   1.779   1.791
18    S        -0.003  -0.055  -0.059  -0.203  -0.308  -0.299  -0.103  -0.182  -0.189
19    I        -0.003   0.016  -0.035   0.090   0.138   0.028  -0.103  -0.072  -0.152
20    V         1.659   1.669   1.677   1.878   1.893   1.907   1.769   1.779   1.791
21    D        -0.003  -0.055  -0.059  -0.024  -0.115  -0.128  -0.103  -0.182  -0.189
22    K         1.659   1.669   1.677   1.561   1.577   1.591   1.769   1.779   1.791
23    H        -1.211  -1.200  -1.191  -1.113  -1.128  -1.080  -1.039  -1.021  -1.005
24    -        -0.151  -0.146  -0.132  -0.279  -0.260  -0.247  -0.337  -0.327  -0.306
25    -        -0.151  -0.146  -0.132  -0.298  -0.289  -0.266  -0.337  -0.327  -0.306
26    -        -0.151  -0.146  -0.132  -0.327  -0.309  -0.295  -0.337  -0.327  -0.306
27    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
28    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
29    S        -1.211  -1.200  -1.191  -1.331  -1.333  -1.298  -1.039  -1.021  -1.005
30    Q        -1.211  -1.200  -1.191  -1.343  -1.340  -1.309  -1.039  -1.021  -1.005
31    G        -0.003  -0.055  -0.059   0.178   0.098   0.084  -0.103  -0.182  -0.189
32    Q        -1.211  -1.200  -1.191  -1.220  -1.196  -1.187  -1.039  -1.021  -1.005
33    Q        -1.211  -1.200  -1.191  -1.406  -1.420  -1.372  -1.039  -1.021  -1.005
34    Q        -0.003   0.016  -0.035   0.051   0.079   0.004  -0.103  -0.072  -0.152
35    Q        -1.211  -1.200  -1.191  -1.145  -1.135  -1.112  -1.039  -1.021  -1.005
36    P        -1.211  -1.200  -1.191  -0.978  -0.935  -0.946  -1.039  -1.021  -1.005
37    H        -0.003   0.016  -0.035   0.324   0.366   0.269  -0.103  -0.072  -0.152
38    Q        -1.211  -1.200  -1.191  -1.024  -0.990  -0.992  -1.039  -1.021  -1.005
39    K        -1.211  -1.200  -1.191  -1.209  -1.188  -1.176  -1.039  -1.021  -1.005
40    Q        -1.211  -1.200  -1.191  -1.406  -1.420  -1.372  -1.039  -1.021  -1.005
41    H        -1.211  -1.200  -1.191  -0.864  -0.840  -0.831  -1.039  -1.021  -1.005
42    E        -1.211  -1.200  -1.191  -1.156  -1.135  -1.123  -1.039  -1.021  -1.005
43    V        -1.211  -1.200  -1.191  -1.050  -1.026  -1.017  -1.039  -1.021  -1.005
44    Q        -1.211  -1.200  -1.191  -1.281  -1.283  -1.248  -1.039  -1.021  -1.005
45    P        -0.151  -0.146  -0.132  -0.255  -0.244  -0.223  -0.337  -0.327  -0.306
46    E        -0.003   0.016  -0.035  -0.228  -0.214  -0.283  -0.103  -0.072  -0.152
47    S         1.659   1.669   1.677   1.526   1.520   1.556   1.769   1.779   1.791
48    K        -1.211  -1.200  -1.191  -1.417  -1.410  -1.384  -1.039  -1.021  -1.005
49    S        -1.211  -1.200  -1.191  -1.161  -1.133  -1.128  -1.039  -1.021  -1.005
50    P        -1.211  -1.200  -1.191  -1.177  -1.167  -1.144  -1.039  -1.021  -1.005
51    R        -1.211  -1.200  -1.191  -1.270  -1.250  -1.237  -1.039  -1.021  -1.005
52    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
53    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
54    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
55    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
56    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
57    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
58    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
59    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
60    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
61    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
62    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
63    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
64    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
65    V        -1.211  -1.200  -1.191  -0.888  -0.864  -0.856  -1.039  -1.021  -1.005
66    T        -0.003   0.057  -0.018   0.178   0.282   0.154  -0.103  -0.009  -0.125
67    T        -0.003  -0.055  -0.059   0.074  -0.012  -0.026  -0.103  -0.182  -0.189
68    P         1.659   1.669   1.677   1.683   1.714   1.713   1.769   1.779   1.791
69    L        -1.211  -1.200  -1.191  -1.097  -1.057  -1.064  -1.039  -1.021  -1.005
70    K        -0.003  -0.055  -0.059  -0.203  -0.300  -0.306  -0.103  -0.182  -0.189
71    P        -0.003   0.016  -0.035  -0.020   0.030  -0.076  -0.103  -0.072  -0.152
72    K        -0.003   0.057  -0.018  -0.008   0.115  -0.038  -0.103  -0.009  -0.125
73    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
74    R         1.659   1.669   1.677   1.752   1.776   1.781   1.769   1.779   1.791
75    L        -1.211  -1.200  -1.191  -1.156  -1.104  -1.123  -1.039  -1.021  -1.005
76    A        -0.003   0.016  -0.035   0.243   0.271   0.192  -0.103  -0.072  -0.152
77    I        -1.211  -1.200  -1.191  -1.009  -0.989  -0.976  -1.039  -1.021  -1.005
78    P        -0.003  -0.055  -0.059  -0.072  -0.146  -0.178  -0.103  -0.182  -0.189
79    I         1.659   1.669   1.677   1.828   1.851   1.857   1.769   1.779   1.791
80    S        -1.211  -1.200  -1.191  -1.140  -1.119  -1.107  -1.039  -1.021  -1.005
81    S        -0.003  -0.055  -0.059  -0.190  -0.290  -0.284  -0.103  -0.182  -0.189
82    P        -0.003  -0.055  -0.059  -0.088  -0.176  -0.197  -0.103  -0.182  -0.189
83    Q        -1.211  -1.200  -1.191  -1.177  -1.162  -1.144  -1.039  -1.021  -1.005
84    R        -1.211  -1.200  -1.191  -1.150  -1.108  -1.117  -1.039  -1.021  -1.005
85    S        -0.151  -0.146  -0.132  -0.514  -0.518  -0.482  -0.337  -0.327  -0.306
86    T        -0.151  -0.146  -0.132  -0.350  -0.350  -0.318  -0.337  -0.327  -0.306
87    T        -1.211  -1.200  -1.191  -1.050  -1.038  -1.017  -1.039  -1.021  -1.005
88    N        -1.211  -1.200  -1.191  -1.292  -1.256  -1.259  -1.039  -1.021  -1.005
89    Q        -0.003   0.016  -0.035  -0.108  -0.085  -0.173  -0.103  -0.072  -0.152
90    S        -0.003   0.057  -0.018  -0.261  -0.181  -0.288  -0.103  -0.009  -0.125
91    P         1.659   1.669   1.677   1.621   1.633   1.651   1.769   1.779   1.791
92    V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
93    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
94    D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
95    H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
96    A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
97    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
98    P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
99    I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
100   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
101   T        -0.003   0.016  -0.035   0.024   0.068  -0.041  -0.103  -0.072  -0.152
102   D        -1.211  -1.200  -1.191  -1.377  -1.387  -1.344  -1.039  -1.021  -1.005
103   Q        -1.211  -1.200  -1.191  -1.383  -1.376  -1.349  -1.039  -1.021  -1.005
104   D        -0.003  -0.055  -0.059  -0.068  -0.172  -0.180  -0.103  -0.182  -0.189
105   L        -1.211  -1.200  -1.191  -1.030  -0.987  -0.997  -1.039  -1.021  -1.005
106   I        -1.211  -1.200  -1.191  -0.933  -0.887  -0.900  -1.039  -1.021  -1.005
107   Y        -0.003  -0.055  -0.059   0.299   0.211   0.198  -0.103  -0.182  -0.189
108   K         1.659   1.669   1.677   1.561   1.577   1.591   1.769   1.779   1.791
109   L        -0.003  -0.055  -0.059  -0.004  -0.071  -0.085  -0.103  -0.182  -0.189
110   A         1.659   1.669   1.677   1.870   1.875   1.899   1.769   1.779   1.791
111   A        -1.211  -1.200  -1.191  -1.237  -1.241  -1.204  -1.039  -1.021  -1.005
112   K        -0.003  -0.055  -0.059  -0.036  -0.101  -0.110  -0.103  -0.182  -0.189
113   H        -1.211  -1.200  -1.191  -1.113  -1.128  -1.080  -1.039  -1.021  -1.005
114   R        -0.003  -0.055  -0.059   0.063  -0.010  -0.033  -0.103  -0.182  -0.189
115   E         1.659   1.669   1.677   1.500   1.492   1.529   1.769   1.779   1.791
116   I         1.659   1.669   1.677   1.828   1.851   1.857   1.769   1.779   1.791
117   N        -1.211  -1.200  -1.191  -1.108  -1.078  -1.075  -1.039  -1.021  -1.005
118   E        -0.003  -0.055  -0.059  -0.190  -0.292  -0.279  -0.103  -0.182  -0.189
119   L        -0.003  -0.055  -0.059   0.129   0.073   0.070  -0.103  -0.182  -0.189
120   S        -0.003   0.057  -0.018  -0.261  -0.181  -0.288  -0.103  -0.009  -0.125
121   F        -1.211  -1.200  -1.191  -1.118  -1.123  -1.085  -1.039  -1.021  -1.005
122   K         1.659   1.669   1.677   1.561   1.577   1.591   1.769   1.779   1.791
123   L         1.659   1.669   1.677   1.623   1.638   1.652   1.769   1.779   1.791
124   E        -1.211  -1.200  -1.191  -1.248  -1.205  -1.215  -1.039  -1.021  -1.005
125   V        -1.211  -1.200  -1.191  -1.161  -1.171  -1.128  -1.039  -1.021  -1.005
126   A        -0.003  -0.055  -0.059   0.129   0.030   0.020  -0.103  -0.182  -0.189
127   Q        -1.211  -1.200  -1.191  -1.199  -1.180  -1.166  -1.039  -1.021  -1.005
128   K        -1.211  -1.200  -1.191  -1.140  -1.112  -1.107  -1.039  -1.021  -1.005
129   E         1.659   1.669   1.677   1.500   1.492   1.529   1.769   1.779   1.791
130   L         1.659   1.669   1.677   1.623   1.638   1.652   1.769   1.779   1.791
131   K         1.659   1.669   1.677   1.561   1.577   1.591   1.769   1.779   1.791
132   Q        -0.003  -0.055  -0.059   0.063  -0.019  -0.017  -0.103  -0.182  -0.189
133   L         1.659   1.669   1.677   1.623   1.638   1.652   1.769   1.779   1.791
134   E        -0.003  -0.055  -0.059  -0.190  -0.292  -0.279  -0.103  -0.182  -0.189
135   L        -1.211  -1.200  -1.191  -1.343  -1.327  -1.309  -1.039  -1.021  -1.005
136   Q        -1.211  -1.200  -1.191  -1.383  -1.376  -1.349  -1.039  -1.021  -1.005
137   F        -1.211  -1.200  -1.191  -0.938  -0.921  -0.905  -1.039  -1.021  -1.005
138   K        -1.211  -1.200  -1.191  -1.113  -1.070  -1.080  -1.039  -1.021  -1.005
139   D        -1.211  -1.200  -1.191  -1.237  -1.195  -1.204  -1.039  -1.021  -1.005
140   T        -1.211  -1.200  -1.191  -1.092  -1.063  -1.059  -1.039  -1.021  -1.005
141   L        -0.003  -0.055  -0.059  -0.004  -0.071  -0.085  -0.103  -0.182  -0.189
142   P        -0.151  -0.146  -0.132  -0.255  -0.244  -0.223  -0.337  -0.327  -0.306
143   R        -0.151  -0.146  -0.132  -0.022  -0.011   0.010  -0.337  -0.327  -0.306
144   N        -0.151  -0.146  -0.132  -0.239  -0.228  -0.207  -0.337  -0.327  -0.306
145   G         1.659   1.669   1.677   1.774   1.786   1.803   1.769   1.779   1.791
146   Q        -0.151  -0.146  -0.132  -0.083  -0.072  -0.051  -0.337  -0.327  -0.306
147   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
148   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
149   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
150   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
151   N         1.659   1.669   1.677   1.505   1.506   1.535   1.769   1.779   1.791
152   Q         1.659   1.669   1.677   1.659   1.664   1.688   1.769   1.779   1.791
153   N         1.659   1.669   1.677   1.505   1.506   1.535   1.769   1.779   1.791
154   P        -0.003  -0.055  -0.059   0.071   0.009  -0.010  -0.103  -0.182  -0.189
155   S        -1.211  -1.200  -1.191  -1.161  -1.127  -1.128  -1.039  -1.021  -1.005
156   E        -0.003  -0.055  -0.059  -0.170  -0.263  -0.254  -0.103  -0.182  -0.189
157   Y        -1.211  -1.200  -1.191  -1.204  -1.232  -1.171  -1.039  -1.021  -1.005
158   L        -0.003  -0.055  -0.059  -0.040  -0.110  -0.127  -0.103  -0.182  -0.189
159   S        -0.003   0.016  -0.035  -0.129  -0.107  -0.176  -0.103  -0.072  -0.152
160   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
161   F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
162   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
163   K        -0.151  -0.146  -0.132  -0.377  -0.365  -0.344  -0.337  -0.327  -0.306
164   R         1.659   1.669   1.677   1.731   1.743   1.760   1.769   1.779   1.791
165   I        -0.151  -0.146  -0.132  -0.168  -0.157  -0.136  -0.337  -0.327  -0.306
166   Q         1.659   1.669   1.677   1.654   1.666   1.684   1.769   1.779   1.791
167   Q        -0.151  -0.146  -0.132  -0.360  -0.349  -0.328  -0.337  -0.327  -0.306
168   T        -0.151  -0.146  -0.132  -0.176  -0.165  -0.144  -0.337  -0.327  -0.306
169   F        -0.151  -0.146  -0.132   0.008   0.020   0.040  -0.337  -0.327  -0.306
170   V        -0.151  -0.146  -0.132  -0.223  -0.212  -0.191  -0.337  -0.327  -0.306
171   D        -0.151  -0.146  -0.132  -0.327  -0.316  -0.295  -0.337  -0.327  -0.306
172   V         1.659   1.669   1.677   1.870   1.882   1.899   1.769   1.779   1.791
173   N         1.659   1.669   1.677   1.632   1.644   1.662   1.769   1.779   1.791
174   N        -0.151  -0.146  -0.132  -0.279  -0.268  -0.247  -0.337  -0.327  -0.306
175   S         1.659   1.669   1.677   1.532   1.544   1.562   1.769   1.779   1.791
176   P         1.659   1.669   1.677   1.621   1.633   1.651   1.769   1.779   1.791
177   N         1.659   1.669   1.677   1.632   1.644   1.662   1.769   1.779   1.791
178   M        -0.151  -0.146  -0.132   0.068   0.079   0.100  -0.337  -0.327  -0.306
179   L        -0.151  -0.146  -0.132  -0.168  -0.157  -0.136  -0.337  -0.327  -0.306
180   K        -0.151  -0.146  -0.132  -0.303  -0.292  -0.271  -0.337  -0.327  -0.306
181   G        -0.151  -0.146  -0.132  -0.145  -0.133  -0.113  -0.337  -0.327  -0.306
182   K         1.659   1.669   1.677   1.599   1.611   1.629   1.769   1.779   1.791
183   K        -0.151  -0.146  -0.132  -0.360  -0.349  -0.328  -0.337  -0.327  -0.306
184   S         1.659   1.669   1.677   1.532   1.544   1.562   1.769   1.779   1.791
185   I        -0.151  -0.146  -0.132   0.046   0.057   0.077  -0.337  -0.327  -0.306
186   N        -0.151  -0.146  -0.132  -0.426  -0.415  -0.394  -0.337  -0.327  -0.306
187   D        -0.151  -0.146  -0.132  -0.279  -0.268  -0.247  -0.337  -0.327  -0.306
188   F        -0.151  -0.146  -0.132  -0.106  -0.095  -0.074  -0.337  -0.327  -0.306
189   F        -0.151  -0.146  -0.132   0.008   0.020   0.040  -0.337  -0.327  -0.306
190   S        -0.151  -0.146  -0.132  -0.410  -0.398  -0.378  -0.337  -0.327  -0.306
191   K        -0.151  -0.146  -0.132  -0.303  -0.292  -0.271  -0.337  -0.327  -0.306
192   P        -0.151  -0.146  -0.132  -0.255  -0.244  -0.223  -0.337  -0.327  -0.306
193   N         1.659   1.669   1.677   1.632   1.644   1.662   1.769   1.779   1.791
194   N        -0.151  -0.146  -0.132  -0.247  -0.236  -0.215  -0.337  -0.327  -0.306
195   N        -0.151  -0.146  -0.132  -0.319  -0.308  -0.287  -0.337  -0.327  -0.306
196   V        -0.151  -0.146  -0.132   0.031   0.042   0.062  -0.337  -0.327  -0.306
197   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
198   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
199   N        -0.151  -0.146  -0.132  -0.247  -0.236  -0.215  -0.337  -0.327  -0.306
200   S         1.659   1.669   1.677   1.532   1.544   1.562   1.769   1.779   1.791
201   N        -0.151  -0.146  -0.132  -0.426  -0.415  -0.394  -0.337  -0.327  -0.306
202   I        -0.151  -0.146  -0.132  -0.271  -0.260  -0.239  -0.337  -0.327  -0.306
203   N        -0.151  -0.146  -0.132  -0.239  -0.228  -0.207  -0.337  -0.327  -0.306
204   N        -0.151  -0.146  -0.132  -0.279  -0.268  -0.247  -0.337  -0.327  -0.306
205   T        -0.151  -0.146  -0.132  -0.145  -0.133  -0.113  -0.337  -0.327  -0.306
206   L        -0.151  -0.146  -0.132  -0.207  -0.196  -0.175  -0.337  -0.327  -0.306
207   P        -0.151  -0.146  -0.132  -0.255  -0.244  -0.223  -0.337  -0.327  -0.306
208   N        -0.151  -0.146  -0.132  -0.279  -0.268  -0.247  -0.337  -0.327  -0.306
209   R         1.659   1.669   1.677   1.731   1.743   1.760   1.769   1.779   1.791
210   K        -0.151  -0.146  -0.132  -0.303  -0.292  -0.271  -0.337  -0.327  -0.306
211   P        -0.151  -0.146  -0.132  -0.106  -0.095  -0.074  -0.337  -0.327  -0.306
212   N        -0.151  -0.146  -0.132  -0.279  -0.268  -0.247  -0.337  -0.327  -0.306
213   P        -0.151  -0.146  -0.132  -0.255  -0.244  -0.223  -0.337  -0.327  -0.306
214   P        -0.151  -0.146  -0.132  -0.287  -0.276  -0.255  -0.337  -0.327  -0.306
215   P        -0.151  -0.146  -0.132  -0.344  -0.333  -0.312  -0.337  -0.327  -0.306
216   N        -0.151  -0.146  -0.132  -0.279  -0.268  -0.247  -0.337  -0.327  -0.306
217   R        -0.003  -0.055  -0.059  -0.036  -0.134  -0.149  -0.103  -0.182  -0.189
218   S        -0.003  -0.055  -0.059  -0.203  -0.308  -0.299  -0.103  -0.182  -0.189
219   Q        -1.211  -1.200  -1.191  -1.009  -0.984  -0.976  -1.039  -1.021  -1.005
220   R        -1.211  -1.200  -1.191  -1.050  -1.044  -1.017  -1.039  -1.021  -1.005
221   M        -1.211  -1.200  -1.191  -0.908  -0.908  -0.875  -1.039  -1.021  -1.005
222   Q        -1.211  -1.200  -1.191  -1.040  -1.020  -1.007  -1.039  -1.021  -1.005
223   N        -1.211  -1.200  -1.191  -1.215  -1.219  -1.182  -1.039  -1.021  -1.005
224   I        -0.003   0.057  -0.018   0.220   0.318   0.197  -0.103  -0.009  -0.125
225   A        -0.003  -0.055  -0.059   0.086  -0.029  -0.030  -0.103  -0.182  -0.189
226   P         1.659   1.669   1.677   1.683   1.714   1.713   1.769   1.779   1.791
227   S        -1.211  -1.200  -1.191  -1.275  -1.286  -1.242  -1.039  -1.021  -1.005
228   R        -1.211  -1.200  -1.191  -1.220  -1.201  -1.187  -1.039  -1.021  -1.005
229   S        -0.003   0.016  -0.035  -0.072  -0.060  -0.113  -0.103  -0.072  -0.152
230   S        -1.211  -1.200  -1.191  -1.326  -1.308  -1.293  -1.039  -1.021  -1.005
231   E        -1.211  -1.200  -1.191  -1.337  -1.304  -1.304  -1.039  -1.021  -1.005
232   S        -0.003  -0.055  -0.059  -0.084  -0.171  -0.159  -0.103  -0.182  -0.189
233   T        -1.211  -1.200  -1.191  -1.097  -1.104  -1.064  -1.039  -1.021  -1.005
234   P        -0.003   0.016  -0.035   0.121   0.172   0.081  -0.103  -0.072  -0.152
235   T        -1.211  -1.200  -1.191  -1.129  -1.110  -1.096  -1.039  -1.021  -1.005
236   S        -0.003   0.016  -0.035  -0.165  -0.151  -0.217  -0.103  -0.072  -0.152
237   G        -1.211  -1.200  -1.191  -1.071  -1.047  -1.038  -1.039  -1.021  -1.005
238   P        -1.211  -1.200  -1.191  -0.825  -0.767  -0.792  -1.039  -1.021  -1.005
239   P        -0.003  -0.055  -0.059  -0.072  -0.146  -0.178  -0.103  -0.182  -0.189
240   L        -0.003   0.016  -0.035  -0.072  -0.026  -0.126  -0.103  -0.072  -0.152
241   L        -0.003  -0.055  -0.059   0.051  -0.006  -0.021  -0.103  -0.182  -0.189
242   P        -0.003  -0.055  -0.059  -0.072  -0.146  -0.178  -0.103  -0.182  -0.189
243   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
244   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
245   P         1.659   1.669   1.677   1.621   1.633   1.651   1.769   1.779   1.791
246   R         1.659   1.669   1.677   1.731   1.743   1.760   1.769   1.779   1.791
247   N        -0.151  -0.146  -0.132  -0.401  -0.390  -0.369  -0.337  -0.327  -0.306
248   T        -0.151  -0.146  -0.132  -0.255  -0.244  -0.223  -0.337  -0.327  -0.306
249   M        -0.151  -0.146  -0.132  -0.083  -0.072  -0.051  -0.337  -0.327  -0.306
250   K         1.659   1.669   1.677   1.599   1.611   1.629   1.769   1.779   1.791
251   N         1.659   1.669   1.677   1.632   1.644   1.662   1.769   1.779   1.791
252   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
253   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
254   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
255   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
256   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
257   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
258   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
259   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
260   E         1.659   1.669   1.677   1.544   1.546   1.574   1.769   1.779   1.791
261   N         1.659   1.669   1.677   1.505   1.506   1.535   1.769   1.779   1.791
262   T        -0.151  -0.146  -0.132  -0.041  -0.025  -0.009  -0.337  -0.327  -0.306
263   P        -0.151  -0.146  -0.132  -0.407  -0.399  -0.375  -0.337  -0.327  -0.306
264   F        -0.003  -0.055  -0.059   0.186   0.100   0.073  -0.103  -0.182  -0.189
265   L        -0.003   0.016  -0.035   0.051   0.093   0.011  -0.103  -0.072  -0.152
266   Q        -1.211  -1.200  -1.191  -1.303  -1.279  -1.270  -1.039  -1.021  -1.005
267   R        -1.211  -1.200  -1.191  -1.314  -1.301  -1.281  -1.039  -1.021  -1.005
268   I        -0.003  -0.055  -0.059   0.063  -0.023  -0.049  -0.103  -0.182  -0.189
269   L        -1.211  -1.200  -1.191  -0.938  -0.884  -0.905  -1.039  -1.021  -1.005
270   N        -1.211  -1.200  -1.191  -1.292  -1.269  -1.259  -1.039  -1.021  -1.005
271   K        -0.003  -0.055  -0.059  -0.112  -0.186  -0.200  -0.103  -0.182  -0.189
272   F         1.659   1.669   1.677   1.944   1.973   1.974   1.769   1.779   1.791
273   N        -1.211  -1.200  -1.191  -0.989  -0.952  -0.956  -1.039  -1.021  -1.005
274   Q        -1.211  -1.200  -1.191  -1.209  -1.180  -1.176  -1.039  -1.021  -1.005
275   M        -0.003  -0.055  -0.059   0.239   0.138   0.123  -0.103  -0.182  -0.189
276   N        -1.211  -1.200  -1.191  -1.150  -1.117  -1.117  -1.039  -1.021  -1.005
277   M        -1.211  -1.200  -1.191  -1.097  -1.117  -1.064  -1.039  -1.021  -1.005
278   E        -0.003  -0.055  -0.059  -0.190  -0.292  -0.279  -0.103  -0.182  -0.189
279   E         1.659   1.669   1.677   1.500   1.492   1.529   1.769   1.779   1.791
280   D        -1.211  -1.200  -1.191  -1.281  -1.270  -1.248  -1.039  -1.021  -1.005
281   E        -0.003   0.016  -0.035  -0.170  -0.153  -0.218  -0.103  -0.072  -0.152
282   F        -0.003  -0.055  -0.059   0.354   0.290   0.270  -0.103  -0.182  -0.189
283   D         1.659   1.669   1.677   1.717   1.734   1.747   1.769   1.779   1.791
284   D         1.659   1.669   1.677   1.717   1.734   1.747   1.769   1.779   1.791
285   L        -1.211  -1.200  -1.191  -1.040  -0.997  -1.007  -1.039  -1.021  -1.005
286   L        -0.003   0.016  -0.035  -0.024   0.015  -0.072  -0.103  -0.072  -0.152
287   E        -0.151  -0.146  -0.132  -0.193  -0.189  -0.161  -0.337  -0.327  -0.306
288   K         1.659   1.669   1.677   1.557   1.572   1.586   1.769   1.779   1.791
289   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
290   R        -0.003   0.016  -0.035   0.094   0.142   0.042  -0.103  -0.072  -0.152
291   K        -1.211  -1.200  -1.191  -1.417  -1.403  -1.384  -1.039  -1.021  -1.005
292   S        -0.003   0.057  -0.018  -0.170  -0.074  -0.198  -0.103  -0.009  -0.125
293   K        -1.211  -1.200  -1.191  -0.973  -0.931  -0.941  -1.039  -1.021  -1.005
294   K        -0.003  -0.055  -0.059  -0.060  -0.124  -0.138  -0.103  -0.182  -0.189
295   D        -0.003  -0.055  -0.059   0.152   0.091   0.078  -0.103  -0.182  -0.189
296   H        -0.003   0.016  -0.035   0.201   0.248   0.132  -0.103  -0.072  -0.152
297   Y        -0.003  -0.055  -0.059   0.368   0.295   0.281  -0.103  -0.182  -0.189
298   Y        -0.003  -0.055  -0.059   0.299   0.211   0.198  -0.103  -0.182  -0.189
299   I        -0.003  -0.055  -0.059   0.205   0.137   0.119  -0.103  -0.182  -0.189
300   K        -0.003   0.016  -0.035  -0.052  -0.016  -0.095  -0.103  -0.072  -0.152
301   E        -0.003  -0.055  -0.059  -0.228  -0.335  -0.323  -0.103  -0.182  -0.189
302   N        -1.211  -1.200  -1.191  -1.071  -1.033  -1.038  -1.039  -1.021  -1.005
303   L        -0.003   0.016  -0.035   0.067   0.099   0.029  -0.103  -0.072  -0.152
304   G        -0.003  -0.055  -0.059   0.094  -0.004  -0.015  -0.103  -0.182  -0.189
305   Y         1.659   1.669   1.677   1.977   1.987   2.006   1.769   1.779   1.791
306   E        -0.003   0.016  -0.035  -0.170  -0.153  -0.218  -0.103  -0.072  -0.152
307   Y        -0.003   0.016  -0.035   0.250   0.282   0.187  -0.103  -0.072  -0.152
308   D         1.659   1.669   1.677   1.717   1.734   1.747   1.769   1.779   1.791
309   E        -0.003  -0.055  -0.059  -0.137  -0.225  -0.216  -0.103  -0.182  -0.189
310   V        -0.151  -0.146  -0.132   0.055   0.081   0.086  -0.337  -0.327  -0.306
311   R        -0.151  -0.146  -0.132  -0.303  -0.293  -0.271  -0.337  -0.327  -0.306
312   S        -0.151  -0.146  -0.132  -0.514  -0.518  -0.482  -0.337  -0.327  -0.306
313   E        -0.003  -0.055  -0.059  -0.186  -0.274  -0.274  -0.103  -0.182  -0.189
314   D         1.659   1.669   1.677   1.717   1.734   1.747   1.769   1.779   1.791
315   E        -0.003  -0.055  -0.059  -0.190  -0.292  -0.279  -0.103  -0.182  -0.189
316   D         1.659   1.669   1.677   1.717   1.734   1.747   1.769   1.779   1.791
317   D        -1.211  -1.200  -1.191  -1.259  -1.245  -1.226  -1.039  -1.021  -1.005
318   E        -0.003  -0.055  -0.059  -0.228  -0.335  -0.323  -0.103  -0.182  -0.189
319   E        -0.003   0.057  -0.018  -0.068   0.040  -0.099  -0.103  -0.009  -0.125
320   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
321   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
322   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
323   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
324   F        -1.211  -1.200  -1.191  -1.150  -1.150  -1.117  -1.039  -1.021  -1.005
325   E        -0.003  -0.055  -0.059  -0.170  -0.263  -0.254  -0.103  -0.182  -0.189
326   P        -1.211  -1.200  -1.191  -1.004  -0.973  -0.971  -1.039  -1.021  -1.005
327   M        -0.003   0.057  -0.018   0.261   0.363   0.244  -0.103  -0.009  -0.125
328   G        -0.151  -0.146  -0.132  -0.247  -0.236  -0.215  -0.337  -0.327  -0.306
329   D         1.659   1.669   1.677   1.731   1.743   1.760   1.769   1.779   1.791
330   I         1.659   1.669   1.677   1.838   1.850   1.867   1.769   1.779   1.791
331   P         1.659   1.669   1.677   1.621   1.633   1.651   1.769   1.779   1.791
332   V        -0.151  -0.146  -0.132  -0.075  -0.064  -0.043  -0.337  -0.327  -0.306
333   H        -0.151  -0.146  -0.132  -0.022  -0.011   0.010  -0.337  -0.327  -0.306
334   L         1.659   1.669   1.677   1.676   1.688   1.706   1.769   1.779   1.791
335   F         1.659   1.669   1.677   1.923   1.935   1.952   1.769   1.779   1.791
336   K         1.659   1.669   1.677   1.599   1.611   1.629   1.769   1.779   1.791
337   R         1.659   1.669   1.677   1.731   1.743   1.760   1.769   1.779   1.791
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P47129
Output conservation file - output/P47129
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
