1     M         1.582   1.599   1.679   1.736   1.760   1.881   1.723   1.747   1.876
2     -        -0.609  -0.594  -0.532  -0.893  -0.871  -0.774  -0.740  -0.720  -0.638
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
19    S        -0.184  -0.309  -0.411  -0.269  -0.440  -0.602  -0.202  -0.362  -0.491
20    I        -0.184  -0.267  -0.394  -0.059  -0.169  -0.378  -0.202  -0.308  -0.470
21    R         1.582   1.599   1.679   1.690   1.713   1.836   1.723   1.747   1.876
22    P         0.372   0.398   0.153   0.530   0.566   0.178   0.333   0.366  -0.010
23    A         1.582   1.599   1.679   1.577   1.592   1.724   1.723   1.747   1.876
24    T         0.657   0.633   0.619   0.555   0.505   0.413   0.440   0.386   0.305
25    H         1.582   1.599   1.679   1.690   1.715   1.836   1.723   1.747   1.876
26    A         1.582   1.599   1.679   1.577   1.592   1.724   1.723   1.747   1.876
27    G         1.582   1.599   1.679   1.550   1.567   1.697   1.723   1.747   1.876
28    S         0.657   0.723   0.648   0.380   0.484   0.354   0.440   0.556   0.364
29    W         1.582   1.599   1.679   1.782   1.806   1.926   1.723   1.747   1.876
30    Y         1.582   1.599   1.679   1.615   1.638   1.762   1.723   1.747   1.876
31    S         0.101   0.074   0.009  -0.180  -0.244  -0.323  -0.095  -0.156  -0.241
32    N        -0.876  -0.906  -0.866  -0.896  -0.965  -0.903  -0.843  -0.869  -0.795
33    R        -0.876  -0.801  -0.849  -0.824  -0.714  -0.776  -0.843  -0.766  -0.778
34    A        -0.128  -0.113  -0.076  -0.232  -0.216  -0.164  -0.415  -0.394  -0.357
35    Q        -1.268  -1.207  -1.189  -1.156  -1.079  -1.037  -1.057  -1.002  -0.938
36    E        -0.876  -0.841  -0.868  -0.903  -0.860  -0.882  -0.843  -0.811  -0.797
37    L         0.962   0.981   0.805   0.896   0.931   0.680   0.975   1.002   0.670
38    S        -0.591  -0.572  -0.532  -0.871  -0.843  -0.758  -0.736  -0.716  -0.645
39    Q        -1.268  -1.264  -1.196  -1.237  -1.258  -1.136  -1.057  -1.043  -0.943
40    Q         0.907   0.889   0.772   1.081   1.059   0.875   0.885   0.851   0.607
41    L         0.962   0.947   0.804   0.900   0.891   0.688   0.975   0.946   0.669
42    H        -1.161  -1.077  -1.147  -0.974  -0.852  -0.967  -0.950  -0.866  -0.899
43    T        -1.161  -1.183  -1.161  -0.939  -0.992  -0.981  -0.950  -0.968  -0.912
44    Y        -0.413  -0.364  -0.445  -0.314  -0.221  -0.365  -0.522  -0.445  -0.537
45    L        -0.413  -0.479  -0.477  -0.455  -0.524  -0.517  -0.522  -0.588  -0.578
46    I        -0.983  -0.913  -0.896  -1.184  -1.106  -1.047  -0.950  -0.888  -0.824
47    K        -0.641  -0.605  -0.543  -0.629  -0.572  -0.473  -0.791  -0.750  -0.656
48    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
49    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
50    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
51    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
52    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
53    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
54    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
55    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
56    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
57    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
58    S         0.019  -0.038  -0.029  -0.242  -0.325  -0.318  -0.193  -0.284  -0.287
59    T        -0.609  -0.606  -0.537  -0.873  -0.873  -0.751  -0.740  -0.738  -0.644
60    L        -1.065  -1.036  -0.937  -1.202  -1.123  -1.012  -1.014  -0.980  -0.857
61    K        -1.268  -1.226  -1.187  -1.229  -1.170  -1.110  -1.057  -1.015  -0.937
62    G        -1.553  -1.548  -1.464  -1.526  -1.536  -1.415  -1.164  -1.152  -1.039
63    P        -0.413  -0.344  -0.439  -0.304  -0.226  -0.337  -0.522  -0.445  -0.536
64    I        -0.021  -0.027  -0.003  -0.173  -0.163  -0.127  -0.308  -0.303  -0.266
65    H        -1.161  -1.062  -1.143  -0.972  -0.818  -0.975  -0.950  -0.851  -0.896
66    N         0.372   0.517   0.164   0.473   0.652   0.184   0.333   0.541   0.008
67    A         0.372   0.343   0.137   0.492   0.446   0.151   0.333   0.289  -0.034
68    R         0.962   0.981   0.805   1.139   1.165   0.914   0.975   1.002   0.670
69    I        -0.413  -0.469  -0.480  -0.384  -0.468  -0.465  -0.522  -0.594  -0.586
70    I        -0.021  -0.037  -0.017  -0.281  -0.284  -0.250  -0.308  -0.320  -0.285
71    I         0.962   0.947   0.804   1.006   0.996   0.790   0.975   0.946   0.669
72    C        -0.483  -0.474  -0.484  -0.684  -0.686  -0.638  -0.629  -0.618  -0.593
73    P         1.582   1.599   1.679   1.655   1.675   1.801   1.723   1.747   1.876
74    H         1.582   1.599   1.679   1.690   1.715   1.836   1.723   1.747   1.876
75    A         1.582   1.599   1.679   1.577   1.592   1.724   1.723   1.747   1.876
76    G         1.582   1.599   1.679   1.550   1.567   1.697   1.723   1.747   1.876
77    Y         0.372   0.381   0.151   0.520   0.532   0.193   0.333   0.344  -0.011
78    R        -1.268  -1.284  -1.203  -1.149  -1.197  -1.068  -1.057  -1.059  -0.949
79    Y         1.582   1.599   1.679   1.615   1.638   1.762   1.723   1.747   1.876
80    C        -0.021  -0.002  -0.006  -0.213  -0.192  -0.173  -0.308  -0.267  -0.266
81    G         1.582   1.599   1.679   1.550   1.567   1.697   1.723   1.747   1.876
82    P        -0.698  -0.682  -0.807  -0.475  -0.458  -0.666  -0.629  -0.608  -0.728
83    T        -0.876  -0.942  -0.888  -0.669  -0.741  -0.656  -0.843  -0.897  -0.814
84    M        -0.198  -0.204  -0.104  -0.391  -0.411  -0.261  -0.522  -0.528  -0.397
85    A         0.372   0.312   0.134   0.447   0.352   0.061   0.333   0.244  -0.038
86    Y        -1.161  -1.143  -1.172  -0.915  -0.876  -0.923  -0.950  -0.932  -0.921
87    S        -0.698  -0.679  -0.574  -0.971  -0.931  -0.783  -0.843  -0.818  -0.686
88    Y         0.494   0.508   0.574   0.370   0.390   0.481   0.119   0.139   0.212
89    A        -1.161  -1.193  -1.178  -1.017  -1.076  -1.062  -0.950  -0.975  -0.926
90    S        -0.876  -0.905  -0.876  -0.957  -0.969  -0.937  -0.843  -0.857  -0.801
91    L         0.101   0.115   0.041   0.049   0.081  -0.011  -0.095  -0.066  -0.186
92    D         1.582   1.599   1.679   1.602   1.620   1.749   1.723   1.747   1.876
93    L        -0.198  -0.170  -0.083  -0.416  -0.363  -0.232  -0.522  -0.484  -0.369
94    N        -0.876  -0.860  -0.866  -1.016  -1.001  -0.961  -0.843  -0.823  -0.794
95    R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
96    N         0.442   0.458   0.553   0.238   0.265   0.408   0.012   0.036   0.169
97    V         0.101   0.130   0.030   0.086   0.105  -0.031  -0.095  -0.074  -0.209
98    K         0.962   0.927   0.795   1.027   0.982   0.814   0.975   0.914   0.652
99    R         1.582   1.599   1.679   1.690   1.713   1.836   1.723   1.747   1.876
100   I        -0.413  -0.364  -0.445  -0.399  -0.304  -0.434  -0.522  -0.445  -0.537
101   F         0.962   0.981   0.805   1.121   1.144   0.896   0.975   1.002   0.670
102   I         0.101   0.043   0.009   0.002  -0.085  -0.172  -0.095  -0.181  -0.241
103   L         0.372   0.343   0.137   0.403   0.376   0.104   0.333   0.289  -0.034
104   G         1.582   1.599   1.679   1.550   1.567   1.697   1.723   1.747   1.876
105   P         1.582   1.599   1.679   1.655   1.675   1.801   1.723   1.747   1.876
106   S         1.582   1.599   1.679   1.352   1.378   1.503   1.723   1.747   1.876
107   H         1.582   1.599   1.679   1.690   1.715   1.836   1.723   1.747   1.876
108   H         0.962   0.886   0.793   1.148   1.053   0.912   0.975   0.845   0.647
109   I        -0.021  -0.066  -0.016  -0.148  -0.196  -0.117  -0.308  -0.355  -0.285
110   Y         1.582   1.599   1.679   1.607   1.629   1.753   1.723   1.747   1.876
111   F         0.657   0.606   0.617   0.636   0.531   0.501   0.440   0.333   0.301
112   K         0.372   0.312   0.134   0.476   0.394   0.135   0.333   0.244  -0.038
113   N         0.155   0.104   0.025   0.248   0.175  -0.004   0.012  -0.069  -0.204
114   Q        -1.268  -1.221  -1.190  -1.190  -1.134  -1.086  -1.057  -1.014  -0.939
115   I        -0.591  -0.547  -0.533  -0.603  -0.532  -0.502  -0.736  -0.693  -0.645
116   L         0.101   0.064   0.012  -0.027  -0.091  -0.150  -0.095  -0.164  -0.237
117   V         0.101   0.059   0.020   0.040  -0.033  -0.112  -0.095  -0.160  -0.224
118   S         0.962   0.981   0.805   0.810   0.839   0.608   0.975   1.002   0.670
119   A        -1.268  -1.249  -1.190  -1.133  -1.109  -1.021  -1.057  -1.034  -0.939
120   F         0.372   0.362   0.140   0.589   0.571   0.248   0.333   0.317  -0.029
121   S        -1.268  -1.269  -1.199  -1.280  -1.284  -1.153  -1.057  -1.049  -0.945
122   E        -0.876  -0.942  -0.888  -0.903  -1.005  -0.953  -0.843  -0.897  -0.814
123   L        -0.413  -0.355  -0.453  -0.358  -0.256  -0.412  -0.522  -0.447  -0.549
124   E         0.101   0.057   0.004   0.012  -0.091  -0.176  -0.095  -0.177  -0.247
125   T         1.582   1.599   1.679   1.620   1.646   1.767   1.723   1.747   1.876
126   P         1.582   1.599   1.679   1.655   1.675   1.801   1.723   1.747   1.876
127   L         0.494   0.532   0.585   0.304   0.379   0.426   0.119   0.187   0.235
128   G         1.582   1.599   1.679   1.550   1.567   1.697   1.723   1.747   1.876
129   N        -0.021  -0.003  -0.015  -0.069  -0.062  -0.058  -0.308  -0.295  -0.286
130   L        -0.184  -0.171  -0.367  -0.154  -0.125  -0.413  -0.202  -0.183  -0.435
131   K        -0.591  -0.609  -0.523  -0.622  -0.645  -0.512  -0.736  -0.743  -0.633
132   V         1.582   1.599   1.679   1.586   1.606   1.733   1.723   1.747   1.876
133   D         1.582   1.599   1.679   1.602   1.620   1.749   1.723   1.747   1.876
134   T        -0.591  -0.588  -0.530  -0.682  -0.680  -0.590  -0.736  -0.724  -0.641
135   D        -0.876  -0.890  -0.858  -0.912  -0.934  -0.908  -0.843  -0.850  -0.787
136   L        -0.591  -0.608  -0.526  -0.771  -0.782  -0.659  -0.736  -0.742  -0.637
137   C        -0.876  -0.895  -0.872  -0.642  -0.673  -0.651  -0.843  -0.857  -0.800
138   K        -0.876  -0.886  -0.864  -0.768  -0.783  -0.734  -0.843  -0.853  -0.794
139   T        -0.591  -0.544  -0.513  -0.650  -0.584  -0.521  -0.736  -0.680  -0.622
140   L         1.582   1.599   1.679   1.447   1.479   1.597   1.723   1.747   1.876
141   I        -1.268  -1.256  -1.189  -1.200  -1.157  -1.062  -1.057  -1.040  -0.938
142   Q        -1.268  -1.269  -1.193  -1.169  -1.183  -1.050  -1.057  -1.049  -0.941
143   K        -1.065  -1.039  -0.937  -1.322  -1.311  -1.130  -1.014  -0.983  -0.857
144   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
145   Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
146   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
147   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
148   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
149   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
150   K        -0.983  -0.909  -0.896  -1.135  -1.041  -0.984  -0.950  -0.883  -0.824
151   K        -1.268  -1.276  -1.201  -1.109  -1.109  -0.978  -1.057  -1.053  -0.947
152   L        -0.591  -0.588  -0.530  -0.828  -0.817  -0.754  -0.736  -0.724  -0.641
153   F         0.372   0.361   0.143   0.591   0.575   0.257   0.333   0.316  -0.025
154   K        -0.698  -0.736  -0.812  -0.588  -0.675  -0.785  -0.629  -0.672  -0.734
155   P        -0.413  -0.441  -0.467  -0.423  -0.471  -0.546  -0.522  -0.553  -0.570
156   M         0.962   0.886   0.793   1.184   1.087   0.937   0.975   0.845   0.647
157   D        -0.413  -0.446  -0.462  -0.580  -0.606  -0.615  -0.522  -0.543  -0.557
158   H        -1.268  -1.281  -1.205  -1.226  -1.257  -1.131  -1.057  -1.058  -0.950
159   D        -0.021  -0.036  -0.012  -0.127  -0.150  -0.098  -0.308  -0.326  -0.281
160   T        -0.483  -0.501  -0.479  -0.511  -0.528  -0.488  -0.629  -0.640  -0.587
161   D         1.582   1.599   1.679   1.602   1.620   1.749   1.723   1.747   1.876
162   M        -0.876  -0.898  -0.851  -0.768  -0.800  -0.733  -0.843  -0.854  -0.779
163   A        -0.698  -0.710  -0.805  -0.551  -0.583  -0.746  -0.629  -0.645  -0.727
164   E         1.582   1.599   1.679   1.582   1.609   1.729   1.723   1.747   1.876
165   H         1.582   1.599   1.679   1.690   1.715   1.836   1.723   1.747   1.876
166   S         0.962   0.886   0.793   0.835   0.749   0.640   0.975   0.845   0.647
167   L         0.494   0.514   0.579   0.225   0.260   0.354   0.119   0.151   0.224
168   E         1.582   1.599   1.679   1.582   1.609   1.729   1.723   1.747   1.876
169   M         1.582   1.599   1.679   1.736   1.760   1.881   1.723   1.747   1.876
170   Q         0.442   0.460   0.554   0.352   0.381   0.520   0.012   0.038   0.170
171   L        -0.876  -0.855  -0.856  -0.790  -0.762  -0.759  -0.843  -0.819  -0.786
172   P         1.582   1.599   1.679   1.655   1.675   1.801   1.723   1.747   1.876
173   M        -0.483  -0.543  -0.501  -0.392  -0.474  -0.424  -0.629  -0.680  -0.610
174   L         0.657   0.702   0.669   0.450   0.532   0.447   0.440   0.517   0.406
175   V        -0.641  -0.591  -0.545  -0.615  -0.539  -0.466  -0.791  -0.738  -0.658
176   E        -1.293  -1.280  -1.217  -1.124  -1.117  -1.016  -1.070  -1.054  -0.959
177   T        -0.967  -0.976  -0.908  -0.897  -0.900  -0.786  -0.930  -0.932  -0.832
178   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
179   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
180   W        -0.876  -0.812  -0.848  -0.921  -0.830  -0.905  -0.843  -0.764  -0.774
181   R        -0.128  -0.146  -0.087  -0.193  -0.234  -0.171  -0.415  -0.444  -0.374
182   E        -1.161  -1.088  -1.141  -0.912  -0.799  -0.912  -0.950  -0.875  -0.894
183   I        -1.268  -1.276  -1.201  -1.263  -1.263  -1.166  -1.057  -1.053  -0.947
184   S        -1.553  -1.555  -1.458  -1.431  -1.429  -1.313  -1.164  -1.157  -1.035
185   L        -1.161  -1.183  -1.174  -1.046  -1.081  -1.038  -0.950  -0.966  -0.923
186   D        -0.698  -0.602  -0.793  -0.584  -0.443  -0.745  -0.629  -0.519  -0.714
187   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
188   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
189   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
190   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
191   T        -1.553  -1.515  -1.456  -1.351  -1.285  -1.224  -1.164  -1.128  -1.033
192   V        -0.021  -0.010  -0.014  -0.110  -0.098  -0.087  -0.308  -0.297  -0.283
193   K         0.372   0.325   0.136   0.459   0.395   0.108   0.333   0.260  -0.035
194   V         0.657   0.755   0.693   0.564   0.725   0.603   0.440   0.615   0.455
195   F        -0.413  -0.320  -0.432  -0.424  -0.286  -0.450  -0.522  -0.407  -0.522
196   P         1.582   1.599   1.679   1.655   1.675   1.801   1.723   1.747   1.876
197   M        -0.413  -0.384  -0.460  -0.455  -0.401  -0.513  -0.522  -0.482  -0.559
198   M         0.494   0.493   0.564   0.361   0.348   0.421   0.119   0.107   0.191
199   V         0.494   0.508   0.574   0.282   0.305   0.387   0.119   0.139   0.212
200   S         0.494   0.472   0.556   0.072   0.030   0.166   0.119   0.065   0.175
201   H        -0.876  -0.942  -0.888  -0.737  -0.834  -0.752  -0.843  -0.897  -0.814
202   N        -0.591  -0.603  -0.539  -0.596  -0.630  -0.534  -0.736  -0.745  -0.651
203   S        -0.184  -0.169  -0.383  -0.258  -0.235  -0.539  -0.202  -0.183  -0.456
204   V        -1.553  -1.572  -1.474  -1.441  -1.489  -1.338  -1.164  -1.168  -1.046
205   D        -1.268  -1.250  -1.188  -1.125  -1.105  -0.993  -1.057  -1.034  -0.937
206   V        -0.876  -0.942  -0.888  -0.904  -0.995  -0.917  -0.843  -0.897  -0.814
207   D        -0.876  -0.879  -0.877  -0.812  -0.821  -0.813  -0.843  -0.846  -0.805
208   R        -1.268  -1.224  -1.187  -1.076  -1.019  -0.941  -1.057  -1.013  -0.937
209   C        -1.553  -1.471  -1.453  -1.387  -1.265  -1.243  -1.164  -1.092  -1.031
210   I        -0.591  -0.615  -0.532  -0.779  -0.810  -0.691  -0.736  -0.756  -0.644
211   G        -0.128  -0.123  -0.071  -0.304  -0.309  -0.234  -0.415  -0.410  -0.350
212   N        -0.591  -0.545  -0.519  -0.771  -0.714  -0.663  -0.736  -0.681  -0.630
213   I        -1.268  -1.229  -1.187  -1.350  -1.278  -1.224  -1.057  -1.019  -0.937
214   L         1.582   1.599   1.679   1.447   1.479   1.597   1.723   1.747   1.876
215   S        -0.591  -0.578  -0.533  -0.886  -0.860  -0.779  -0.736  -0.719  -0.646
216   E        -0.413  -0.355  -0.453  -0.324  -0.232  -0.378  -0.522  -0.447  -0.549
217   Y         1.582   1.599   1.679   1.615   1.638   1.762   1.723   1.747   1.876
218   I        -0.591  -0.541  -0.527  -0.764  -0.696  -0.642  -0.736  -0.684  -0.639
219   K        -0.483  -0.534  -0.492  -0.547  -0.618  -0.541  -0.629  -0.672  -0.601
220   D         0.962   1.005   0.810   1.068   1.118   0.871   0.975   1.040   0.679
221   P         0.494   0.495   0.565   0.333   0.330   0.429   0.119   0.112   0.195
222   N        -0.698  -0.750  -0.818  -0.570  -0.665  -0.785  -0.629  -0.688  -0.740
223   N         0.962   0.981   0.805   1.132   1.161   0.917   0.975   1.002   0.670
224   L        -0.876  -0.879  -0.877  -0.983  -0.995  -0.970  -0.843  -0.846  -0.805
225   F         1.582   1.599   1.679   1.673   1.691   1.818   1.723   1.747   1.876
226   I         0.657   0.627   0.620   0.564   0.516   0.469   0.440   0.375   0.308
227   V         0.372   0.461   0.163   0.444   0.569   0.129   0.333   0.459   0.007
228   S         1.582   1.599   1.679   1.352   1.378   1.503   1.723   1.747   1.876
229   S         0.962   0.947   0.804   0.810   0.796   0.607   0.975   0.946   0.669
230   D         1.582   1.599   1.679   1.602   1.620   1.749   1.723   1.747   1.876
231   F         1.582   1.599   1.679   1.673   1.691   1.818   1.723   1.747   1.876
232   C         1.582   1.599   1.679   1.780   1.804   1.924   1.723   1.747   1.876
233   H         1.582   1.599   1.679   1.690   1.715   1.836   1.723   1.747   1.876
234   W         1.582   1.599   1.679   1.782   1.806   1.926   1.723   1.747   1.876
235   G         1.582   1.599   1.679   1.550   1.567   1.697   1.723   1.747   1.876
236   R        -0.413  -0.466  -0.471  -0.392  -0.458  -0.491  -0.522  -0.573  -0.570
237   R         0.657   0.606   0.617   0.724   0.635   0.626   0.440   0.333   0.301
238   F         0.962   0.886   0.793   1.129   1.028   0.894   0.975   0.845   0.647
239   Q        -0.698  -0.671  -0.800  -0.545  -0.506  -0.699  -0.629  -0.601  -0.721
240   Y         1.582   1.599   1.679   1.615   1.638   1.762   1.723   1.747   1.876
241   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
242   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
243   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
244   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
245   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
246   T         0.372   0.275   0.129   0.562   0.435   0.229   0.333   0.189  -0.046
247   G         0.101   0.098   0.036   0.013   0.012  -0.108  -0.095  -0.088  -0.194
248   Y         0.962   0.886   0.793   1.049   0.947   0.791   0.975   0.845   0.647
249   V        -0.021  -0.028  -0.018  -0.233  -0.239  -0.217  -0.308  -0.313  -0.287
250   G        -1.553  -1.572  -1.474  -1.428  -1.430  -1.312  -1.164  -1.168  -1.046
251   S        -0.413  -0.424  -0.472  -0.577  -0.601  -0.626  -0.522  -0.548  -0.576
252   K        -0.967  -0.977  -0.892  -1.018  -1.021  -0.913  -0.930  -0.931  -0.818
253   E        -0.698  -0.763  -0.821  -0.551  -0.646  -0.760  -0.629  -0.700  -0.743
254   E        -1.268  -1.304  -1.213  -1.101  -1.139  -1.002  -1.057  -1.074  -0.956
255   L        -1.161  -1.183  -1.174  -1.041  -1.048  -1.031  -0.950  -0.966  -0.923
256   N        -0.967  -0.945  -0.890  -0.920  -0.881  -0.798  -0.930  -0.905  -0.817
257   D        -0.876  -0.890  -0.853  -0.787  -0.813  -0.755  -0.843  -0.850  -0.782
258   A        -0.983  -0.947  -0.896  -1.152  -1.118  -1.012  -0.950  -0.912  -0.824
259   I        -0.876  -0.859  -0.851  -1.004  -0.963  -0.959  -0.843  -0.811  -0.776
260   Q        -0.967  -0.957  -0.892  -0.983  -0.970  -0.888  -0.930  -0.916  -0.818
261   E        -0.967  -1.001  -0.916  -1.025  -1.080  -0.963  -0.930  -0.951  -0.839
262   E        -0.967  -0.991  -0.903  -0.865  -0.881  -0.745  -0.930  -0.943  -0.827
263   T        -0.609  -0.650  -0.560  -0.709  -0.776  -0.670  -0.740  -0.786  -0.670
264   E         0.759   0.687   0.674   0.741   0.623   0.579   0.628   0.488   0.416
265   V        -0.519  -0.555  -0.520  -0.625  -0.674  -0.629  -0.651  -0.690  -0.630
266   E        -0.462  -0.505  -0.516  -0.454  -0.525  -0.565  -0.558  -0.614  -0.619
267   M        -0.985  -1.007  -0.924  -0.889  -0.925  -0.839  -0.938  -0.954  -0.846
268   L         0.907   0.829   0.761   0.823   0.720   0.608   0.885   0.748   0.586
269   T        -0.462  -0.543  -0.516  -0.386  -0.519  -0.492  -0.558  -0.657  -0.619
270   A        -1.365  -1.336  -1.233  -1.192  -1.150  -1.002  -1.128  -1.097  -0.971
271   R        -0.413  -0.440  -0.477  -0.377  -0.433  -0.529  -0.522  -0.558  -0.582
272   S         0.101   0.099   0.022  -0.088  -0.095  -0.180  -0.095  -0.113  -0.222
273   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
274   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
275   K        -1.161  -1.221  -1.177  -1.012  -1.102  -1.044  -0.950  -1.000  -0.925
276   L        -1.161  -1.193  -1.178  -1.049  -1.092  -1.045  -0.950  -0.975  -0.926
277   S        -0.591  -0.616  -0.540  -0.830  -0.848  -0.714  -0.736  -0.757  -0.653
278   H        -0.983  -1.003  -0.900  -0.999  -1.021  -0.869  -0.950  -0.955  -0.827
279   H        -0.876  -0.916  -0.880  -0.803  -0.877  -0.850  -0.843  -0.877  -0.808
280   Q        -1.268  -1.276  -1.201  -1.137  -1.164  -1.068  -1.057  -1.053  -0.947
281   V        -0.413  -0.439  -0.467  -0.436  -0.456  -0.510  -0.522  -0.541  -0.566
282   P         0.372   0.365   0.142   0.582   0.567   0.254   0.333   0.320  -0.027
283   I         1.582   1.599   1.679   1.553   1.584   1.701   1.723   1.747   1.876
284   W         0.101   0.109   0.052   0.206   0.233   0.152  -0.095  -0.063  -0.168
285   Q        -0.128  -0.123  -0.077  -0.245  -0.251  -0.177  -0.415  -0.413  -0.358
286   S         0.962   0.886   0.793   0.805   0.710   0.578   0.975   0.845   0.647
287   I         1.582   1.599   1.679   1.553   1.584   1.701   1.723   1.747   1.876
288   E         0.372   0.257   0.113   0.453   0.291   0.031   0.333   0.163  -0.070
289   I        -0.876  -0.942  -0.888  -0.909  -0.985  -0.907  -0.843  -0.897  -0.814
290   M         0.657   0.755   0.693   0.512   0.664   0.566   0.440   0.615   0.455
291   D         1.582   1.599   1.679   1.602   1.620   1.749   1.723   1.747   1.876
292   R        -0.876  -0.915  -0.858  -0.738  -0.788  -0.688  -0.843  -0.869  -0.787
293   Y        -0.876  -0.917  -0.879  -0.876  -0.947  -0.905  -0.843  -0.877  -0.807
294   A         0.101   0.007   0.001   0.063  -0.094  -0.113  -0.095  -0.231  -0.253
295   M         0.962   1.005   0.810   1.170   1.229   0.938   0.975   1.040   0.679
296   K        -1.268  -1.220  -1.186  -1.098  -1.042  -0.962  -1.057  -1.011  -0.936
297   T        -0.413  -0.398  -0.456  -0.472  -0.459  -0.557  -0.522  -0.503  -0.556
298   L        -0.198  -0.204  -0.104  -0.514  -0.514  -0.368  -0.522  -0.528  -0.397
299   S        -0.698  -0.761  -0.822  -0.773  -0.868  -0.952  -0.629  -0.698  -0.745
300   D        -1.553  -1.471  -1.453  -1.360  -1.241  -1.221  -1.164  -1.092  -1.031
301   T        -0.591  -0.581  -0.526  -0.652  -0.635  -0.550  -0.736  -0.713  -0.637
302   P        -0.698  -0.646  -0.805  -0.735  -0.669  -0.871  -0.629  -0.573  -0.727
303   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
304   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
305   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
306   R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
307   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
308   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
309   Y         0.101   0.030   0.010   0.047  -0.056  -0.130  -0.095  -0.192  -0.239
310   D        -0.876  -0.839  -0.848  -0.919  -0.879  -0.876  -0.843  -0.804  -0.778
311   A        -0.876  -0.801  -0.845  -0.874  -0.755  -0.840  -0.843  -0.756  -0.775
312   W         0.372   0.257   0.113   0.711   0.557   0.331   0.333   0.163  -0.070
313   K        -0.413  -0.454  -0.478  -0.496  -0.567  -0.603  -0.522  -0.569  -0.582
314   Q        -0.591  -0.630  -0.535  -0.665  -0.744  -0.616  -0.736  -0.769  -0.648
315   Y         0.962   0.886   0.793   1.063   0.966   0.821   0.975   0.845   0.647
316   L        -0.021  -0.020  -0.013  -0.238  -0.213  -0.178  -0.308  -0.298  -0.279
317   E        -0.876  -0.790  -0.844  -0.896  -0.754  -0.849  -0.843  -0.741  -0.770
318   I        -0.876  -0.946  -0.870  -0.871  -0.970  -0.861  -0.843  -0.901  -0.799
319   T         0.657   0.725   0.648   0.555   0.676   0.479   0.440   0.559   0.364
320   G        -0.698  -0.786  -0.825  -0.571  -0.696  -0.777  -0.629  -0.724  -0.748
321   N         1.582   1.599   1.679   1.674   1.700   1.820   1.723   1.747   1.876
322   T         1.582   1.599   1.679   1.620   1.646   1.767   1.723   1.747   1.876
323   I         0.962   0.886   0.793   1.006   0.916   0.771   0.975   0.845   0.647
324   C         1.582   1.599   1.679   1.780   1.804   1.924   1.723   1.747   1.876
325   G         1.582   1.599   1.679   1.550   1.567   1.697   1.723   1.747   1.876
326   E        -0.198  -0.161  -0.080  -0.279  -0.209  -0.092  -0.522  -0.470  -0.365
327   K        -0.184  -0.282  -0.406  -0.009  -0.145  -0.314  -0.202  -0.328  -0.485
328   P         1.582   1.599   1.679   1.655   1.675   1.801   1.723   1.747   1.876
329   I         0.962   0.947   0.804   0.987   0.976   0.751   0.975   0.946   0.669
330   S        -0.876  -0.858  -0.847  -1.043  -0.979  -0.985  -0.843  -0.810  -0.772
331   V        -0.021  -0.039  -0.019  -0.194  -0.212  -0.192  -0.308  -0.324  -0.288
332   I        -0.413  -0.442  -0.465  -0.439  -0.484  -0.524  -0.522  -0.558  -0.568
333   L        -0.184  -0.186  -0.368  -0.142  -0.133  -0.396  -0.202  -0.205  -0.436
334   S        -0.983  -0.988  -0.899  -1.010  -1.021  -0.878  -0.950  -0.944  -0.826
335   A        -0.413  -0.439  -0.467  -0.486  -0.518  -0.581  -0.522  -0.541  -0.566
336   L         0.657   0.645   0.625   0.512   0.501   0.460   0.440   0.410   0.318
337   S         0.101   0.208   0.045  -0.007   0.166  -0.119  -0.095   0.060  -0.183
338   K        -1.161  -1.141  -1.146  -1.055  -1.005  -1.052  -0.950  -0.927  -0.899
339   I        -1.161  -1.143  -1.172  -0.986  -0.952  -1.028  -0.950  -0.932  -0.921
340   R        -0.876  -0.828  -0.847  -0.758  -0.704  -0.716  -0.843  -0.796  -0.777
341   D        -1.619  -1.591  -1.484  -1.441  -1.409  -1.247  -1.210  -1.181  -1.052
342   A        -0.967  -0.931  -0.889  -1.131  -1.086  -0.997  -0.930  -0.892  -0.816
343   G        -0.985  -0.989  -0.904  -1.076  -1.068  -0.965  -0.938  -0.937  -0.827
344   P        -0.609  -0.585  -0.530  -0.886  -0.844  -0.762  -0.740  -0.708  -0.636
345   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
346   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
347   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
348   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
349   S        -0.605  -0.553  -0.528  -0.853  -0.787  -0.724  -0.748  -0.690  -0.638
350   G        -0.605  -0.604  -0.530  -0.783  -0.778  -0.684  -0.748  -0.741  -0.640
351   I        -0.985  -0.965  -0.903  -1.012  -0.985  -0.894  -0.938  -0.914  -0.826
352   K        -1.553  -1.524  -1.454  -1.405  -1.369  -1.261  -1.164  -1.133  -1.032
353   F         0.962   0.947   0.804   1.106   1.084   0.866   0.975   0.946   0.669
354   Q        -0.591  -0.603  -0.532  -0.564  -0.575  -0.480  -0.736  -0.741  -0.644
355   W         0.657   0.596   0.611   0.810   0.701   0.692   0.440   0.315   0.289
356   P        -0.413  -0.408  -0.456  -0.398  -0.374  -0.456  -0.522  -0.498  -0.551
357   N        -1.268  -1.273  -1.193  -1.160  -1.176  -1.050  -1.057  -1.052  -0.941
358   Y         1.582   1.599   1.679   1.615   1.638   1.762   1.723   1.747   1.876
359   S         0.372   0.257   0.113   0.285   0.138  -0.062   0.333   0.163  -0.070
360   Q         0.962   0.886   0.793   1.168   1.075   0.943   0.975   0.845   0.647
361   S         1.582   1.599   1.679   1.352   1.378   1.503   1.723   1.747   1.876
362   S         0.494   0.486   0.564   0.142   0.134   0.259   0.119   0.092   0.193
363   H        -1.268  -1.241  -1.189  -1.042  -1.015  -0.934  -1.057  -1.028  -0.938
364   V         0.962   0.981   0.805   1.067   1.091   0.879   0.975   1.002   0.670
365   T        -1.553  -1.471  -1.453  -1.239  -1.125  -1.087  -1.164  -1.092  -1.031
366   S        -0.983  -0.969  -0.898  -1.165  -1.127  -1.006  -0.950  -0.928  -0.824
367   I        -1.161  -1.193  -1.178  -0.998  -1.032  -1.025  -0.950  -0.975  -0.926
368   D        -1.161  -1.077  -1.147  -1.142  -1.029  -1.092  -0.950  -0.866  -0.899
369   D         0.494   0.524   0.580   0.312   0.361   0.431   0.119   0.172   0.225
370   S         0.372   0.275   0.129   0.275   0.149  -0.057   0.333   0.189  -0.046
371   S         1.582   1.599   1.679   1.352   1.378   1.503   1.723   1.747   1.876
372   V         1.582   1.599   1.679   1.586   1.606   1.733   1.723   1.747   1.876
373   S         1.582   1.599   1.679   1.352   1.378   1.503   1.723   1.747   1.876
374   Y         1.582   1.599   1.679   1.615   1.638   1.762   1.723   1.747   1.876
375   A         0.962   0.886   0.793   1.030   0.924   0.794   0.975   0.845   0.647
376   S         0.372   0.398   0.153   0.270   0.306  -0.030   0.333   0.366  -0.010
377   G         0.657   0.596   0.611   0.557   0.440   0.444   0.440   0.315   0.289
378   Y         0.372   0.312   0.134   0.549   0.472   0.216   0.333   0.244  -0.038
379   V        -0.876  -0.886  -0.864  -0.890  -0.939  -0.888  -0.843  -0.853  -0.794
380   T        -1.365  -1.337  -1.233  -1.186  -1.167  -0.995  -1.128  -1.098  -0.971
381   I         0.841   0.916   0.744   0.740   0.842   0.584   0.773   0.896   0.554
382   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P47085
Output conservation file - output/P47085
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
