1     M         0.931   0.934   0.944   1.187   1.191   1.199   0.961   0.963   0.974
2     P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
19    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
20    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
21    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
22    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
23    A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
24    D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
25    A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
26    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
27    A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
28    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
29    R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
30    D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
31    I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
32    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
33    D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
34    I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
35    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
36    I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
37    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
38    F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
39    A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
40    A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
41    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
42    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
43    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
44    N        -0.705  -0.700  -0.665  -1.001  -0.992  -0.923  -0.885  -0.874  -0.815
45    Y        -0.705  -0.700  -0.665  -0.721  -0.712  -0.651  -0.885  -0.874  -0.815
46    V        -1.662  -1.647  -1.605  -1.459  -1.432  -1.367  -1.500  -1.477  -1.411
47    F         0.931   0.934   0.944   1.029   1.035   1.045   0.961   0.963   0.974
48    P         0.931   0.934   0.944   1.039   1.042   1.055   0.961   0.963   0.974
49    L         0.931   0.934   0.944   0.516   0.522   0.548   0.961   0.963   0.974
50    T        -1.662  -1.647  -1.605  -1.786  -1.748  -1.684  -1.500  -1.477  -1.411
51    K        -0.571  -0.627  -0.640  -0.635  -0.729  -0.759  -0.680  -0.761  -0.777
52    L         0.931   0.934   0.944   0.516   0.522   0.548   0.961   0.963   0.974
53    P        -0.571  -0.538  -0.628  -0.531  -0.474  -0.642  -0.680  -0.628  -0.758
54    D         0.931   0.934   0.944   0.952   0.957   0.970   0.961   0.963   0.974
55    E        -0.571  -0.538  -0.628  -0.407  -0.360  -0.476  -0.680  -0.628  -0.758
56    L         0.931   0.934   0.944   0.516   0.522   0.548   0.961   0.963   0.974
57    M        -0.571  -0.521  -0.625  -0.868  -0.802  -0.890  -0.680  -0.601  -0.754
58    Q        -0.571  -0.627  -0.640  -0.341  -0.425  -0.448  -0.680  -0.761  -0.777
59    E         0.931   0.934   0.944   0.997   1.002   1.015   0.961   0.963   0.974
60    V        -0.571  -0.538  -0.628  -0.677  -0.610  -0.833  -0.680  -0.628  -0.758
61    F        -1.662  -1.647  -1.605  -1.924  -1.891  -1.817  -1.500  -1.477  -1.411
62    S        -0.571  -0.627  -0.640  -0.578  -0.660  -0.670  -0.680  -0.761  -0.777
63    H         0.931   0.934   0.944   1.160   1.164   1.172   0.961   0.963   0.974
64    L        -1.662  -1.647  -1.605  -1.659  -1.614  -1.561  -1.500  -1.477  -1.411
65    P         0.931   0.934   0.944   1.039   1.042   1.055   0.961   0.963   0.974
66    Q         0.931   0.934   0.944   1.112   1.118   1.126   0.961   0.963   0.974
67    P        -1.662  -1.647  -1.605  -1.436  -1.416  -1.345  -1.500  -1.477  -1.411
68    D         0.931   0.934   0.944   0.952   0.957   0.970   0.961   0.963   0.974
69    R         0.931   0.934   0.944   1.029   1.029   1.045   0.961   0.963   0.974
70    L         0.931   0.934   0.944   0.516   0.522   0.548   0.961   0.963   0.974
71    Q        -0.571  -0.521  -0.625  -0.555  -0.478  -0.624  -0.680  -0.601  -0.754
72    L         0.931   0.934   0.944   0.516   0.522   0.548   0.961   0.963   0.974
73    C         0.931   0.934   0.944   1.215   1.217   1.225   0.961   0.963   0.974
74    L         0.931   0.934   0.944   0.516   0.522   0.548   0.961   0.963   0.974
75    V         0.931   0.934   0.944   1.060   1.062   1.076   0.961   0.963   0.974
76    N         0.931   0.934   0.944   0.902   0.905   0.922   0.961   0.963   0.974
77    K         0.931   0.934   0.944   0.927   0.934   0.946   0.961   0.963   0.974
78    R         0.931   0.934   0.944   1.029   1.029   1.045   0.961   0.963   0.974
79    L        -0.571  -0.627  -0.640  -0.934  -1.003  -0.983  -0.680  -0.761  -0.777
80    N        -1.662  -1.647  -1.605  -1.571  -1.554  -1.476  -1.500  -1.477  -1.411
81    K        -0.571  -0.538  -0.628  -0.571  -0.518  -0.656  -0.680  -0.628  -0.758
82    I        -0.571  -0.521  -0.625  -1.042  -0.958  -1.103  -0.680  -0.601  -0.754
83    A        -0.571  -0.538  -0.628  -0.339  -0.286  -0.444  -0.680  -0.628  -0.758
84    T        -1.662  -1.647  -1.605  -1.856  -1.869  -1.752  -1.500  -1.477  -1.411
85    K        -0.571  -0.627  -0.640  -0.566  -0.651  -0.669  -0.680  -0.761  -0.777
86    L        -0.571  -0.627  -0.640  -1.042  -1.126  -1.124  -0.680  -0.761  -0.777
87    L        -0.571  -0.538  -0.628  -0.934  -0.887  -0.973  -0.680  -0.628  -0.758
88    Y         0.931   0.934   0.944   1.105   1.108   1.119   0.961   0.963   0.974
89    R         0.931   0.934   0.944   1.029   1.029   1.045   0.961   0.963   0.974
90    R         0.931   0.934   0.944   1.029   1.029   1.045   0.961   0.963   0.974
91    I         0.931   0.934   0.944   0.848   0.854   0.869   0.961   0.963   0.974
92    Y         0.931   0.934   0.944   1.105   1.108   1.119   0.961   0.963   0.974
93    L         0.931   0.934   0.944   0.516   0.522   0.548   0.961   0.963   0.974
94    N         0.931   0.934   0.944   0.902   0.905   0.922   0.961   0.963   0.974
95    D         0.931   0.934   0.944   0.952   0.957   0.970   0.961   0.963   0.974
96    S         0.931   0.934   0.944   0.891   0.896   0.911   0.961   0.963   0.974
97    N         0.931   0.934   0.944   0.902   0.905   0.922   0.961   0.963   0.974
98    V         0.931   0.934   0.944   1.060   1.062   1.076   0.961   0.963   0.974
99    V         0.931   0.934   0.944   1.060   1.062   1.076   0.961   0.963   0.974
100   K        -1.662  -1.647  -1.605  -1.574  -1.546  -1.478  -1.500  -1.477  -1.411
101   S         0.931   0.934   0.944   0.891   0.896   0.911   0.961   0.963   0.974
102   D         0.931   0.934   0.944   0.952   0.957   0.970   0.961   0.963   0.974
103   F        -0.571  -0.627  -0.640  -0.560  -0.662  -0.701  -0.680  -0.761  -0.777
104   M        -0.571  -0.627  -0.640  -0.321  -0.418  -0.451  -0.680  -0.761  -0.777
105   H        -0.571  -0.521  -0.625  -0.533  -0.459  -0.597  -0.680  -0.601  -0.754
106   L         0.931   0.934   0.944   0.516   0.522   0.548   0.961   0.963   0.974
107   A         0.931   0.934   0.944   1.167   1.170   1.179   0.961   0.963   0.974
108   I        -0.571  -0.538  -0.628  -0.629  -0.577  -0.702  -0.680  -0.628  -0.758
109   N         0.931   0.934   0.944   0.902   0.905   0.922   0.961   0.963   0.974
110   W         0.931   0.934   0.944   1.265   1.268   1.274   0.961   0.963   0.974
111   T        -0.571  -0.538  -0.628  -0.489  -0.432  -0.605  -0.680  -0.628  -0.758
112   L        -0.571  -0.627  -0.640  -0.910  -0.976  -0.954  -0.680  -0.761  -0.777
113   L        -0.571  -0.538  -0.628  -0.950  -0.899  -0.992  -0.680  -0.628  -0.758
114   N        -1.662  -1.647  -1.605  -1.606  -1.564  -1.510  -1.500  -1.477  -1.411
115   L        -1.662  -1.647  -1.605  -1.814  -1.740  -1.711  -1.500  -1.477  -1.411
116   P         0.931   0.934   0.944   1.039   1.042   1.055   0.961   0.963   0.974
117   S        -0.571  -0.627  -0.640  -0.599  -0.684  -0.698  -0.680  -0.761  -0.777
118   S        -1.662  -1.647  -1.605  -1.654  -1.630  -1.556  -1.500  -1.477  -1.411
119   L        -0.571  -0.627  -0.640  -0.966  -1.038  -1.025  -0.680  -0.761  -0.777
120   K        -1.662  -1.647  -1.605  -1.546  -1.499  -1.451  -1.500  -1.477  -1.411
121   E         0.931   0.934   0.944   0.997   1.002   1.015   0.961   0.963   0.974
122   E        -1.662  -1.647  -1.605  -1.445  -1.402  -1.353  -1.500  -1.477  -1.411
123   E        -0.571  -0.627  -0.640  -0.398  -0.472  -0.479  -0.680  -0.761  -0.777
124   S         0.931   0.934   0.944   0.891   0.896   0.911   0.961   0.963   0.974
125   R         0.931   0.934   0.944   1.029   1.029   1.045   0.961   0.963   0.974
126   D        -1.662  -1.647  -1.605  -1.327  -1.287  -1.239  -1.500  -1.477  -1.411
127   I        -0.571  -0.627  -0.640  -0.882  -1.003  -1.052  -0.680  -0.761  -0.777
128   A         0.931   0.934   0.944   1.167   1.170   1.179   0.961   0.963   0.974
129   N         0.931   0.934   0.944   0.902   0.905   0.922   0.961   0.963   0.974
130   C        -1.662  -1.647  -1.605  -1.178  -1.160  -1.095  -1.500  -1.477  -1.411
131   K         0.931   0.934   0.944   0.927   0.934   0.946   0.961   0.963   0.974
132   L         0.931   0.934   0.944   0.516   0.522   0.548   0.961   0.963   0.974
133   K        -1.662  -1.647  -1.605  -1.516  -1.493  -1.422  -1.500  -1.477  -1.411
134   K        -0.571  -0.627  -0.640  -0.806  -0.927  -0.984  -0.680  -0.761  -0.777
135   L         0.931   0.934   0.944   0.516   0.522   0.548   0.961   0.963   0.974
136   I         0.931   0.934   0.944   0.848   0.854   0.869   0.961   0.963   0.974
137   E        -1.662  -1.647  -1.605  -1.461  -1.438  -1.369  -1.500  -1.477  -1.411
138   T         0.931   0.934   0.944   1.085   1.087   1.099   0.961   0.963   0.974
139   L        -0.571  -0.538  -0.628  -0.950  -0.899  -0.992  -0.680  -0.628  -0.758
140   Q        -1.662  -1.647  -1.605  -1.445  -1.435  -1.353  -1.500  -1.477  -1.411
141   N        -0.571  -0.521  -0.625  -0.536  -0.453  -0.640  -0.680  -0.601  -0.754
142   N         0.931   0.934   0.944   0.902   0.905   0.922   0.961   0.963   0.974
143   I        -1.662  -1.647  -1.605  -1.681  -1.656  -1.582  -1.500  -1.477  -1.411
144   H        -0.571  -0.521  -0.625  -0.447  -0.370  -0.520  -0.680  -0.601  -0.754
145   I        -1.662  -1.647  -1.605  -1.681  -1.645  -1.582  -1.500  -1.477  -1.411
146   T        -0.571  -0.627  -0.640  -0.653  -0.784  -0.848  -0.680  -0.761  -0.777
147   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
148   E        -1.662  -1.647  -1.605  -1.507  -1.494  -1.414  -1.500  -1.477  -1.411
149   V        -1.662  -1.647  -1.605  -1.873  -1.842  -1.768  -1.500  -1.477  -1.411
150   I        -0.571  -0.538  -0.628  -0.629  -0.577  -0.702  -0.680  -0.628  -0.758
151   Q         0.931   0.934   0.944   1.112   1.118   1.126   0.961   0.963   0.974
152   W         0.931   0.934   0.944   1.265   1.268   1.274   0.961   0.963   0.974
153   I         0.931   0.934   0.944   0.848   0.854   0.869   0.961   0.963   0.974
154   R         0.931   0.934   0.944   1.029   1.029   1.045   0.961   0.963   0.974
155   I         0.931   0.934   0.944   0.848   0.854   0.869   0.961   0.963   0.974
156   N         0.931   0.934   0.944   0.902   0.905   0.922   0.961   0.963   0.974
157   W         0.931   0.934   0.944   1.265   1.268   1.274   0.961   0.963   0.974
158   D         0.931   0.934   0.944   0.952   0.957   0.970   0.961   0.963   0.974
159   L         0.931   0.934   0.944   0.516   0.522   0.548   0.961   0.963   0.974
160   D         0.931   0.934   0.944   0.952   0.957   0.970   0.961   0.963   0.974
161   S        -1.662  -1.647  -1.605  -1.632  -1.606  -1.535  -1.500  -1.477  -1.411
162   T        -1.662  -1.647  -1.605  -1.459  -1.442  -1.367  -1.500  -1.477  -1.411
163   L        -0.571  -0.627  -0.640  -1.002  -1.079  -1.072  -0.680  -0.761  -0.777
164   Q         0.931   0.934   0.944   1.112   1.118   1.126   0.961   0.963   0.974
165   R        -1.662  -1.647  -1.605  -1.470  -1.432  -1.377  -1.500  -1.477  -1.411
166   S        -1.662  -1.647  -1.605  -1.543  -1.514  -1.449  -1.500  -1.477  -1.411
167   I        -0.571  -0.521  -0.625  -0.531  -0.442  -0.644  -0.680  -0.601  -0.754
168   L         0.931   0.934   0.944   0.516   0.522   0.548   0.961   0.963   0.974
169   S        -1.662  -1.647  -1.605  -1.654  -1.620  -1.556  -1.500  -1.477  -1.411
170   I        -1.662  -1.647  -1.605  -1.814  -1.822  -1.711  -1.500  -1.477  -1.411
171   L         0.931   0.934   0.944   0.516   0.522   0.548   0.961   0.963   0.974
172   C         0.931   0.934   0.944   1.215   1.217   1.225   0.961   0.963   0.974
173   N        -1.662  -1.647  -1.605  -1.451  -1.421  -1.359  -1.500  -1.477  -1.411
174   Q        -1.662  -1.647  -1.605  -1.472  -1.440  -1.379  -1.500  -1.477  -1.411
175   G        -0.571  -0.627  -0.640  -0.342  -0.452  -0.502  -0.680  -0.761  -0.777
176   K        -0.571  -0.538  -0.628  -0.510  -0.458  -0.580  -0.680  -0.628  -0.758
177   S         0.931   0.934   0.944   0.891   0.896   0.911   0.961   0.963   0.974
178   L        -0.571  -0.627  -0.640  -1.042  -1.126  -1.124  -0.680  -0.761  -0.777
179   Q        -0.571  -0.627  -0.640  -0.483  -0.588  -0.634  -0.680  -0.761  -0.777
180   R         0.931   0.934   0.944   1.029   1.029   1.045   0.961   0.963   0.974
181   L         0.931   0.934   0.944   0.516   0.522   0.548   0.961   0.963   0.974
182   E         0.931   0.934   0.944   0.997   1.002   1.015   0.961   0.963   0.974
183   N         0.931   0.934   0.944   0.902   0.905   0.922   0.961   0.963   0.974
184   V         0.931   0.934   0.944   1.060   1.062   1.076   0.961   0.963   0.974
185   T        -0.571  -0.538  -0.628  -0.508  -0.450  -0.629  -0.680  -0.628  -0.758
186   D         0.931   0.934   0.944   0.952   0.957   0.970   0.961   0.963   0.974
187   P         0.931   0.934   0.944   1.039   1.042   1.055   0.961   0.963   0.974
188   A        -1.662  -1.647  -1.605  -1.537  -1.519  -1.443  -1.500  -1.477  -1.411
189   C         0.931   0.934   0.944   1.215   1.217   1.225   0.961   0.963   0.974
190   N         0.931   0.934   0.944   0.902   0.905   0.922   0.961   0.963   0.974
191   D         0.931   0.934   0.944   0.952   0.957   0.970   0.961   0.963   0.974
192   I         0.931   0.934   0.944   0.848   0.854   0.869   0.961   0.963   0.974
193   I         0.931   0.934   0.944   0.848   0.854   0.869   0.961   0.963   0.974
194   S        -0.571  -0.521  -0.625  -0.414  -0.323  -0.531  -0.680  -0.601  -0.754
195   N        -0.571  -0.538  -0.628  -0.830  -0.762  -0.972  -0.680  -0.628  -0.758
196   G         0.931   0.934   0.944   1.245   1.248   1.255   0.961   0.963   0.974
197   H        -1.662  -1.647  -1.605  -1.582  -1.571  -1.486  -1.500  -1.477  -1.411
198   F        -1.662  -1.647  -1.605  -1.424  -1.392  -1.333  -1.500  -1.477  -1.411
199   S         0.931   0.934   0.944   0.891   0.896   0.911   0.961   0.963   0.974
200   R        -0.571  -0.538  -0.628  -0.415  -0.369  -0.495  -0.680  -0.628  -0.758
201   S        -1.662  -1.647  -1.605  -1.412  -1.374  -1.321  -1.500  -1.477  -1.411
202   N         0.931   0.934   0.944   0.902   0.905   0.922   0.961   0.963   0.974
203   V         0.931   0.934   0.944   1.060   1.062   1.076   0.961   0.963   0.974
204   S        -0.571  -0.521  -0.625  -0.489  -0.401  -0.600  -0.680  -0.601  -0.754
205   S         0.931   0.934   0.944   0.891   0.896   0.911   0.961   0.963   0.974
206   F         0.931   0.934   0.944   1.029   1.035   1.045   0.961   0.963   0.974
207   D         0.931   0.934   0.944   0.952   0.957   0.970   0.961   0.963   0.974
208   M        -0.571  -0.627  -0.640  -0.395  -0.501  -0.548  -0.680  -0.761  -0.777
209   A         0.931   0.934   0.944   1.167   1.170   1.179   0.961   0.963   0.974
210   P         0.931   0.934   0.944   1.039   1.042   1.055   0.961   0.963   0.974
211   P         0.931   0.934   0.944   1.039   1.042   1.055   0.961   0.963   0.974
212   N         0.931   0.934   0.944   0.902   0.905   0.922   0.961   0.963   0.974
213   S         0.931   0.934   0.944   0.891   0.896   0.911   0.961   0.963   0.974
214   L        -0.571  -0.627  -0.640  -0.868  -0.927  -0.899  -0.680  -0.761  -0.777
215   P         0.931   0.934   0.944   1.039   1.042   1.055   0.961   0.963   0.974
216   E         0.931   0.934   0.944   0.997   1.002   1.015   0.961   0.963   0.974
217   M        -1.662  -1.647  -1.605  -1.558  -1.508  -1.463  -1.500  -1.477  -1.411
218   V        -1.662  -1.647  -1.605  -1.576  -1.550  -1.480  -1.500  -1.477  -1.411
219   V         0.931   0.934   0.944   1.060   1.062   1.076   0.961   0.963   0.974
220   P        -0.571  -0.627  -0.640  -0.531  -0.633  -0.667  -0.680  -0.761  -0.777
221   E        -1.662  -1.647  -1.605  -1.461  -1.438  -1.369  -1.500  -1.477  -1.411
222   N        -1.662  -1.647  -1.605  -1.582  -1.544  -1.486  -1.500  -1.477  -1.411
223   Y         0.931   0.934   0.944   1.105   1.108   1.119   0.961   0.963   0.974
224   I        -0.571  -0.627  -0.640  -0.882  -1.003  -1.052  -0.680  -0.761  -0.777
225   P         0.931   0.934   0.944   1.039   1.042   1.055   0.961   0.963   0.974
226   N         0.931   0.934   0.944   0.902   0.905   0.922   0.961   0.963   0.974
227   L         0.931   0.934   0.944   0.516   0.522   0.548   0.961   0.963   0.974
228   T        -1.662  -1.647  -1.605  -1.457  -1.421  -1.365  -1.500  -1.477  -1.411
229   K        -1.662  -1.647  -1.605  -1.424  -1.389  -1.333  -1.500  -1.477  -1.411
230   Y         0.931   0.934   0.944   1.105   1.108   1.119   0.961   0.963   0.974
231   L         0.931   0.934   0.944   0.516   0.522   0.548   0.961   0.963   0.974
232   S        -1.662  -1.647  -1.605  -1.639  -1.614  -1.541  -1.500  -1.477  -1.411
233   Q         0.931   0.934   0.944   1.112   1.118   1.126   0.961   0.963   0.974
234   R         0.931   0.934   0.944   1.029   1.029   1.045   0.961   0.963   0.974
235   I         0.931   0.934   0.944   0.848   0.854   0.869   0.961   0.963   0.974
236   S         0.931   0.934   0.944   0.891   0.896   0.911   0.961   0.963   0.974
237   S         0.931   0.934   0.944   0.891   0.896   0.911   0.961   0.963   0.974
238   R        -1.662  -1.647  -1.605  -1.632  -1.614  -1.535  -1.500  -1.477  -1.411
239   L         0.931   0.934   0.944   0.516   0.522   0.548   0.961   0.963   0.974
240   S         0.931   0.934   0.944   0.891   0.896   0.911   0.961   0.963   0.974
241   H         0.931   0.934   0.944   1.160   1.164   1.172   0.961   0.963   0.974
242   M         0.931   0.934   0.944   1.187   1.191   1.199   0.961   0.963   0.974
243   T         0.931   0.934   0.944   1.085   1.087   1.099   0.961   0.963   0.974
244   L         0.931   0.934   0.944   0.516   0.522   0.548   0.961   0.963   0.974
245   F         0.931   0.934   0.944   1.029   1.035   1.045   0.961   0.963   0.974
246   I        -0.571  -0.627  -0.640  -0.568  -0.640  -0.641  -0.680  -0.761  -0.777
247   D         0.931   0.934   0.944   0.952   0.957   0.970   0.961   0.963   0.974
248   P         0.931   0.934   0.944   1.039   1.042   1.055   0.961   0.963   0.974
249   L        -0.571  -0.521  -0.625  -0.882  -0.778  -1.013  -0.680  -0.601  -0.754
250   K        -0.571  -0.627  -0.640  -0.533  -0.610  -0.625  -0.680  -0.761  -0.777
251   L         0.931   0.934   0.944   0.516   0.522   0.548   0.961   0.963   0.974
252   F         0.931   0.934   0.944   1.029   1.035   1.045   0.961   0.963   0.974
253   N         0.931   0.934   0.944   0.902   0.905   0.922   0.961   0.963   0.974
254   Y        -0.571  -0.627  -0.640  -0.325  -0.409  -0.426  -0.680  -0.761  -0.777
255   L        -0.571  -0.627  -0.640  -1.042  -1.126  -1.124  -0.680  -0.761  -0.777
256   Y         0.931   0.934   0.944   1.105   1.108   1.119   0.961   0.963   0.974
257   P         0.931   0.934   0.944   1.039   1.042   1.055   0.961   0.963   0.974
258   L         0.931   0.934   0.944   0.516   0.522   0.548   0.961   0.963   0.974
259   D        -1.662  -1.647  -1.605  -1.565  -1.523  -1.470  -1.500  -1.477  -1.411
260   I        -1.662  -1.647  -1.605  -1.621  -1.583  -1.524  -1.500  -1.477  -1.411
261   K         0.931   0.934   0.944   0.927   0.934   0.946   0.961   0.963   0.974
262   L         0.931   0.934   0.944   0.516   0.522   0.548   0.961   0.963   0.974
263   Q         0.931   0.934   0.944   1.112   1.118   1.126   0.961   0.963   0.974
264   I         0.931   0.934   0.944   0.848   0.854   0.869   0.961   0.963   0.974
265   I        -0.571  -0.627  -0.640  -0.581  -0.655  -0.658  -0.680  -0.761  -0.777
266   D         0.931   0.934   0.944   0.952   0.957   0.970   0.961   0.963   0.974
267   L         0.931   0.934   0.944   0.516   0.522   0.548   0.961   0.963   0.974
268   K         0.931   0.934   0.944   0.927   0.934   0.946   0.961   0.963   0.974
269   L         0.931   0.934   0.944   0.516   0.522   0.548   0.961   0.963   0.974
270   H         0.931   0.934   0.944   1.160   1.164   1.172   0.961   0.963   0.974
271   W         0.931   0.934   0.944   1.265   1.268   1.274   0.961   0.963   0.974
272   R         0.931   0.934   0.944   1.029   1.029   1.045   0.961   0.963   0.974
273   R        -0.571  -0.627  -0.640  -0.525  -0.626  -0.655  -0.680  -0.761  -0.777
274   E         0.931   0.934   0.944   0.997   1.002   1.015   0.961   0.963   0.974
275   F        -0.571  -0.627  -0.640  -0.443  -0.529  -0.549  -0.680  -0.761  -0.777
276   Y        -0.571  -0.538  -0.628  -0.409  -0.354  -0.512  -0.680  -0.628  -0.758
277   N        -0.571  -0.521  -0.625  -0.526  -0.439  -0.631  -0.680  -0.601  -0.754
278   N        -1.662  -1.647  -1.605  -1.512  -1.482  -1.418  -1.500  -1.477  -1.411
279   D        -0.571  -0.538  -0.628  -0.596  -0.537  -0.695  -0.680  -0.628  -0.758
280   Y        -0.571  -0.627  -0.640  -0.372  -0.460  -0.486  -0.680  -0.761  -0.777
281   F         0.931   0.934   0.944   1.016   1.020   1.032   0.961   0.963   0.974
282   V        -0.705  -0.700  -0.665  -0.781  -0.772  -0.710  -0.885  -0.874  -0.815
283   K        -0.705  -0.700  -0.665  -0.816  -0.807  -0.744  -0.885  -0.874  -0.815
284   K        -0.705  -0.700  -0.665  -0.743  -0.734  -0.673  -0.885  -0.874  -0.815
285   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
286   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
287   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
288   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
289   I        -0.571  -0.627  -0.640  -0.882  -1.003  -1.052  -0.680  -0.761  -0.777
290   R        -0.571  -0.521  -0.625  -0.571  -0.490  -0.652  -0.680  -0.601  -0.754
291   P         0.931   0.934   0.944   1.039   1.042   1.055   0.961   0.963   0.974
292   G        -0.571  -0.627  -0.640  -0.500  -0.635  -0.711  -0.680  -0.761  -0.777
293   N        -0.571  -0.538  -0.628  -0.609  -0.556  -0.695  -0.680  -0.628  -0.758
294   -         0.931   0.934   0.944   1.114   1.118   1.128   0.961   0.963   0.974
295   -        -0.705  -0.700  -0.665  -0.668  -0.659  -0.600  -0.885  -0.874  -0.815
296   -        -0.705  -0.700  -0.665  -0.767  -0.758  -0.696  -0.885  -0.874  -0.815
297   P        -1.662  -1.647  -1.605  -1.632  -1.608  -1.535  -1.500  -1.477  -1.411
298   L         0.931   0.934   0.944   0.516   0.522   0.548   0.961   0.963   0.974
299   T         0.931   0.934   0.944   1.085   1.087   1.099   0.961   0.963   0.974
300   K         0.931   0.934   0.944   0.927   0.934   0.946   0.961   0.963   0.974
301   L         0.931   0.934   0.944   0.516   0.522   0.548   0.961   0.963   0.974
302   S         0.931   0.934   0.944   0.891   0.896   0.911   0.961   0.963   0.974
303   E        -0.571  -0.627  -0.640  -0.542  -0.637  -0.666  -0.680  -0.761  -0.777
304   V         0.931   0.934   0.944   1.060   1.062   1.076   0.961   0.963   0.974
305   F         0.931   0.934   0.944   1.029   1.035   1.045   0.961   0.963   0.974
306   D         0.931   0.934   0.944   0.952   0.957   0.970   0.961   0.963   0.974
307   K        -1.662  -1.647  -1.605  -1.646  -1.605  -1.548  -1.500  -1.477  -1.411
308   R         0.931   0.934   0.944   1.029   1.029   1.045   0.961   0.963   0.974
309   T        -0.571  -0.538  -0.628  -0.489  -0.432  -0.605  -0.680  -0.628  -0.758
310   L         0.931   0.934   0.944   0.516   0.522   0.548   0.961   0.963   0.974
311   K         0.931   0.934   0.944   0.927   0.934   0.946   0.961   0.963   0.974
312   I        -0.571  -0.627  -0.640  -0.629  -0.711  -0.719  -0.680  -0.761  -0.777
313   L         0.931   0.934   0.944   0.516   0.522   0.548   0.961   0.963   0.974
314   T         0.931   0.934   0.944   1.085   1.087   1.099   0.961   0.963   0.974
315   I         0.931   0.934   0.944   0.848   0.854   0.869   0.961   0.963   0.974
316   I         0.931   0.934   0.944   0.848   0.854   0.869   0.961   0.963   0.974
317   S         0.931   0.934   0.944   0.891   0.896   0.911   0.961   0.963   0.974
318   W         0.931   0.934   0.944   1.265   1.268   1.274   0.961   0.963   0.974
319   N         0.931   0.934   0.944   0.902   0.905   0.922   0.961   0.963   0.974
320   D        -0.571  -0.521  -0.625  -0.542  -0.456  -0.638  -0.680  -0.601  -0.754
321   T        -1.662  -1.647  -1.605  -1.619  -1.602  -1.522  -1.500  -1.477  -1.411
322   L         0.931   0.934   0.944   0.516   0.522   0.548   0.961   0.963   0.974
323   L        -1.662  -1.647  -1.605  -2.013  -1.961  -1.904  -1.500  -1.477  -1.411
324   K        -0.571  -0.538  -0.628  -0.635  -0.575  -0.736  -0.680  -0.628  -0.758
325   R         0.931   0.934   0.944   1.029   1.029   1.045   0.961   0.963   0.974
326   E         0.931   0.934   0.944   0.997   1.002   1.015   0.961   0.963   0.974
327   T        -1.662  -1.647  -1.605  -1.885  -1.896  -1.780  -1.500  -1.477  -1.411
328   E         0.931   0.934   0.944   0.997   1.002   1.015   0.961   0.963   0.974
329   M        -0.571  -0.521  -0.625  -0.568  -0.495  -0.624  -0.680  -0.601  -0.754
330   L        -0.571  -0.538  -0.628  -1.042  -0.987  -1.107  -0.680  -0.628  -0.758
331   K        -1.662  -1.647  -1.605  -1.539  -1.502  -1.445  -1.500  -1.477  -1.411
332   D        -0.571  -0.521  -0.625  -0.542  -0.456  -0.638  -0.680  -0.601  -0.754
333   F         0.931   0.934   0.944   1.029   1.035   1.045   0.961   0.963   0.974
334   K        -0.571  -0.627  -0.640  -0.536  -0.616  -0.630  -0.680  -0.761  -0.777
335   E         0.931   0.934   0.944   0.997   1.002   1.015   0.961   0.963   0.974
336   F         0.931   0.934   0.944   1.029   1.035   1.045   0.961   0.963   0.974
337   E        -1.662  -1.647  -1.605  -1.459  -1.431  -1.367  -1.500  -1.477  -1.411
338   N        -1.662  -1.647  -1.605  -1.541  -1.515  -1.447  -1.500  -1.477  -1.411
339   L        -0.571  -0.627  -0.640  -1.042  -1.126  -1.124  -0.680  -0.761  -0.777
340   E        -0.571  -0.627  -0.640  -0.507  -0.599  -0.620  -0.680  -0.761  -0.777
341   D         0.931   0.934   0.944   0.952   0.957   0.970   0.961   0.963   0.974
342   L         0.931   0.934   0.944   0.516   0.522   0.548   0.961   0.963   0.974
343   S         0.931   0.934   0.944   0.891   0.896   0.911   0.961   0.963   0.974
344   L         0.931   0.934   0.944   0.516   0.522   0.548   0.961   0.963   0.974
345   I         0.931   0.934   0.944   0.848   0.854   0.869   0.961   0.963   0.974
346   S         0.931   0.934   0.944   0.891   0.896   0.911   0.961   0.963   0.974
347   I        -0.571  -0.627  -0.640  -0.568  -0.640  -0.641  -0.680  -0.761  -0.777
348   K        -0.571  -0.627  -0.640  -0.571  -0.659  -0.676  -0.680  -0.761  -0.777
349   Q         0.931   0.934   0.944   1.112   1.118   1.126   0.961   0.963   0.974
350   D        -0.571  -0.627  -0.640  -0.607  -0.704  -0.732  -0.680  -0.761  -0.777
351   V        -1.662  -1.647  -1.605  -1.576  -1.546  -1.480  -1.500  -1.477  -1.411
352   H        -1.662  -1.647  -1.605  -1.391  -1.358  -1.301  -1.500  -1.477  -1.411
353   I        -0.571  -0.538  -0.628  -0.629  -0.577  -0.702  -0.680  -0.628  -0.758
354   L         0.931   0.934   0.944   0.516   0.522   0.548   0.961   0.963   0.974
355   V        -0.571  -0.627  -0.640  -0.531  -0.638  -0.676  -0.680  -0.761  -0.777
356   D        -1.662  -1.647  -1.605  -1.643  -1.610  -1.546  -1.500  -1.477  -1.411
357   L         0.931   0.934   0.944   0.516   0.522   0.548   0.961   0.963   0.974
358   F         0.931   0.934   0.944   1.029   1.035   1.045   0.961   0.963   0.974
359   S        -0.571  -0.627  -0.640  -0.652  -0.743  -0.766  -0.680  -0.761  -0.777
360   S        -1.662  -1.647  -1.605  -1.595  -1.564  -1.499  -1.500  -1.477  -1.411
361   L         0.931   0.934   0.944   0.516   0.522   0.548   0.961   0.963   0.974
362   T        -0.571  -0.521  -0.625  -0.545  -0.465  -0.620  -0.680  -0.601  -0.754
363   N        -0.571  -0.538  -0.628  -0.594  -0.544  -0.677  -0.680  -0.628  -0.758
364   L         0.931   0.934   0.944   0.516   0.522   0.548   0.961   0.963   0.974
365   K         0.931   0.934   0.944   0.927   0.934   0.946   0.961   0.963   0.974
366   R         0.931   0.934   0.944   1.029   1.029   1.045   0.961   0.963   0.974
367   L         0.931   0.934   0.944   0.516   0.522   0.548   0.961   0.963   0.974
368   K         0.931   0.934   0.944   0.927   0.934   0.946   0.961   0.963   0.974
369   M        -0.571  -0.627  -0.640  -0.310  -0.405  -0.437  -0.680  -0.761  -0.777
370   D         0.931   0.934   0.944   0.952   0.957   0.970   0.961   0.963   0.974
371   F         0.931   0.934   0.944   1.029   1.035   1.045   0.961   0.963   0.974
372   L         0.931   0.934   0.944   0.516   0.522   0.548   0.961   0.963   0.974
373   E        -0.571  -0.627  -0.640  -0.447  -0.527  -0.541  -0.680  -0.761  -0.777
374   E        -0.571  -0.538  -0.628  -0.542  -0.485  -0.643  -0.680  -0.628  -0.758
375   Y        -0.571  -0.627  -0.640  -0.409  -0.503  -0.534  -0.680  -0.761  -0.777
376   V        -0.571  -0.627  -0.640  -0.425  -0.517  -0.537  -0.680  -0.761  -0.777
377   P         0.931   0.934   0.944   1.039   1.042   1.055   0.961   0.963   0.974
378   E        -0.571  -0.627  -0.640  -0.447  -0.527  -0.541  -0.680  -0.761  -0.777
379   P         0.931   0.934   0.944   1.039   1.042   1.055   0.961   0.963   0.974
380   T        -0.571  -0.627  -0.640  -0.414  -0.508  -0.532  -0.680  -0.761  -0.777
381   N        -0.571  -0.521  -0.625  -0.663  -0.577  -0.754  -0.680  -0.601  -0.754
382   P        -0.571  -0.627  -0.640  -0.443  -0.533  -0.553  -0.680  -0.761  -0.777
383   H        -1.662  -1.647  -1.605  -1.410  -1.397  -1.319  -1.500  -1.477  -1.411
384   I        -0.571  -0.627  -0.640  -0.629  -0.711  -0.719  -0.680  -0.761  -0.777
385   F         0.931   0.934   0.944   1.029   1.035   1.045   0.961   0.963   0.974
386   L         0.931   0.934   0.944   0.516   0.522   0.548   0.961   0.963   0.974
387   S        -0.571  -0.538  -0.628  -0.539  -0.490  -0.605  -0.680  -0.628  -0.758
388   I         0.931   0.934   0.944   0.848   0.854   0.869   0.961   0.963   0.974
389   L         0.931   0.934   0.944   0.516   0.522   0.548   0.961   0.963   0.974
390   L         0.931   0.934   0.944   0.516   0.522   0.548   0.961   0.963   0.974
391   A        -0.571  -0.521  -0.625  -0.529  -0.456  -0.593  -0.680  -0.601  -0.754
392   C         0.931   0.934   0.944   1.215   1.217   1.225   0.961   0.963   0.974
393   S        -1.662  -1.647  -1.605  -1.639  -1.604  -1.541  -1.500  -1.477  -1.411
394   K        -1.662  -1.647  -1.605  -1.621  -1.587  -1.524  -1.500  -1.477  -1.411
395   L         0.931   0.934   0.944   0.516   0.522   0.548   0.961   0.963   0.974
396   Q         0.931   0.934   0.944   1.112   1.118   1.126   0.961   0.963   0.974
397   F         0.931   0.934   0.944   1.029   1.035   1.045   0.961   0.963   0.974
398   I        -0.571  -0.627  -0.640  -0.882  -1.003  -1.052  -0.680  -0.761  -0.777
399   D         0.931   0.934   0.944   0.952   0.957   0.970   0.961   0.963   0.974
400   L         0.931   0.934   0.944   0.516   0.522   0.548   0.961   0.963   0.974
401   R         0.931   0.934   0.944   1.029   1.029   1.045   0.961   0.963   0.974
402   Y        -0.571  -0.521  -0.625  -0.443  -0.363  -0.526  -0.680  -0.601  -0.754
403   D        -0.571  -0.521  -0.625  -0.542  -0.456  -0.638  -0.680  -0.601  -0.754
404   G        -0.571  -0.627  -0.640  -0.338  -0.447  -0.496  -0.680  -0.761  -0.777
405   L        -1.662  -1.647  -1.605  -1.902  -1.864  -1.796  -1.500  -1.477  -1.411
406   I        -0.571  -0.521  -0.625  -0.632  -0.541  -0.735  -0.680  -0.601  -0.754
407   P        -1.662  -1.647  -1.605  -1.795  -1.756  -1.693  -1.500  -1.477  -1.411
408   Q        -0.571  -0.538  -0.628  -0.398  -0.342  -0.500  -0.680  -0.628  -0.758
409   I         0.931   0.934   0.944   0.848   0.854   0.869   0.961   0.963   0.974
410   I         0.931   0.934   0.944   0.848   0.854   0.869   0.961   0.963   0.974
411   N        -1.662  -1.647  -1.605  -1.619  -1.600  -1.522  -1.500  -1.477  -1.411
412   I        -0.571  -0.538  -0.628  -0.882  -0.813  -1.020  -0.680  -0.628  -0.758
413   Q        -0.571  -0.627  -0.640  -0.417  -0.511  -0.547  -0.680  -0.761  -0.777
414   E        -0.571  -0.627  -0.640  -0.407  -0.483  -0.491  -0.680  -0.761  -0.777
415   N        -0.571  -0.521  -0.625  -0.663  -0.577  -0.754  -0.680  -0.601  -0.754
416   K        -0.571  -0.627  -0.640  -0.571  -0.659  -0.676  -0.680  -0.761  -0.777
417   F         0.931   0.934   0.944   1.029   1.035   1.045   0.961   0.963   0.974
418   Q        -1.662  -1.647  -1.605  -1.522  -1.504  -1.428  -1.500  -1.477  -1.411
419   L        -0.571  -0.627  -0.640  -0.950  -1.019  -1.004  -0.680  -0.761  -0.777
420   N        -1.662  -1.647  -1.605  -1.849  -1.859  -1.745  -1.500  -1.477  -1.411
421   Q        -0.571  -0.627  -0.640  -0.344  -0.428  -0.452  -0.680  -0.761  -0.777
422   Q        -1.662  -1.647  -1.605  -1.580  -1.562  -1.484  -1.500  -1.477  -1.411
423   C         0.931   0.934   0.944   1.215   1.217   1.225   0.961   0.963   0.974
424   N        -1.662  -1.647  -1.605  -1.443  -1.405  -1.351  -1.500  -1.477  -1.411
425   C         0.931   0.934   0.944   1.215   1.217   1.225   0.961   0.963   0.974
426   T        -1.662  -1.647  -1.605  -1.589  -1.567  -1.493  -1.500  -1.477  -1.411
427   N        -1.662  -1.647  -1.605  -1.704  -1.671  -1.604  -1.500  -1.477  -1.411
428   C         0.931   0.934   0.944   1.215   1.217   1.225   0.961   0.963   0.974
429   Q        -1.662  -1.647  -1.605  -1.422  -1.414  -1.331  -1.500  -1.477  -1.411
430   I        -0.571  -0.521  -0.625  -0.439  -0.346  -0.560  -0.680  -0.601  -0.754
431   V         0.931   0.934   0.944   1.060   1.062   1.076   0.961   0.963   0.974
432   F         0.931   0.934   0.944   1.029   1.035   1.045   0.961   0.963   0.974
433   S        -1.662  -1.647  -1.605  -1.543  -1.501  -1.449  -1.500  -1.477  -1.411
434   D        -0.571  -0.538  -0.628  -0.607  -0.550  -0.709  -0.680  -0.628  -0.758
435   I         0.931   0.934   0.944   0.848   0.854   0.869   0.961   0.963   0.974
436   L         0.931   0.934   0.944   0.516   0.522   0.548   0.961   0.963   0.974
437   K        -0.571  -0.627  -0.640  -0.536  -0.616  -0.630  -0.680  -0.761  -0.777
438   G        -0.571  -0.538  -0.628  -0.316  -0.258  -0.441  -0.680  -0.628  -0.758
439   K         0.931   0.934   0.944   0.927   0.934   0.946   0.961   0.963   0.974
440   I        -0.571  -0.627  -0.640  -0.643  -0.726  -0.738  -0.680  -0.761  -0.777
441   F         0.931   0.934   0.944   1.029   1.035   1.045   0.961   0.963   0.974
442   M        -1.662  -1.647  -1.605  -1.393  -1.389  -1.303  -1.500  -1.477  -1.411
443   F        -0.571  -0.627  -0.640  -0.541  -0.640  -0.676  -0.680  -0.761  -0.777
444   P        -1.662  -1.647  -1.605  -1.589  -1.572  -1.493  -1.500  -1.477  -1.411
445   E        -0.571  -0.627  -0.640  -0.554  -0.649  -0.680  -0.680  -0.761  -0.777
446   D         0.931   0.934   0.944   0.952   0.957   0.970   0.961   0.963   0.974
447   Y        -0.571  -0.627  -0.640  -0.338  -0.422  -0.442  -0.680  -0.761  -0.777
448   Y        -1.662  -1.647  -1.605  -1.447  -1.424  -1.355  -1.500  -1.477  -1.411
449   I        -0.571  -0.538  -0.628  -0.882  -0.813  -1.020  -0.680  -0.628  -0.758
450   H        -1.662  -1.647  -1.605  -1.488  -1.469  -1.395  -1.500  -1.477  -1.411
451   D         0.931   0.934   0.944   0.952   0.957   0.970   0.961   0.963   0.974
452   L        -0.571  -0.538  -0.628  -1.042  -0.987  -1.107  -0.680  -0.628  -0.758
453   Q        -1.662  -1.647  -1.605  -1.445  -1.435  -1.353  -1.500  -1.477  -1.411
454   D         0.931   0.934   0.944   0.952   0.957   0.970   0.961   0.963   0.974
455   I        -0.571  -0.627  -0.640  -0.882  -1.003  -1.052  -0.680  -0.761  -0.777
456   A        -0.571  -0.627  -0.640  -0.432  -0.541  -0.589  -0.680  -0.761  -0.777
457   A         0.931   0.934   0.944   1.167   1.170   1.179   0.961   0.963   0.974
458   K         0.931   0.934   0.944   0.927   0.934   0.946   0.961   0.963   0.974
459   D         0.931   0.934   0.944   0.952   0.957   0.970   0.961   0.963   0.974
460   I         0.931   0.934   0.944   0.848   0.854   0.869   0.961   0.963   0.974
461   F         0.931   0.934   0.944   1.029   1.035   1.045   0.961   0.963   0.974
462   K        -0.571  -0.627  -0.640  -0.545  -0.627  -0.642  -0.680  -0.761  -0.777
463   M         0.931   0.934   0.944   1.187   1.191   1.199   0.961   0.963   0.974
464   M         0.931   0.934   0.944   1.187   1.191   1.199   0.961   0.963   0.974
465   K        -0.571  -0.538  -0.628  -0.571  -0.518  -0.656  -0.680  -0.628  -0.758
466   Y         0.931   0.934   0.944   1.105   1.108   1.119   0.961   0.963   0.974
467   L         0.931   0.934   0.944   0.516   0.522   0.548   0.961   0.963   0.974
468   S         0.931   0.934   0.944   0.891   0.896   0.911   0.961   0.963   0.974
469   L         0.931   0.934   0.944   0.516   0.522   0.548   0.961   0.963   0.974
470   L         0.931   0.934   0.944   0.516   0.522   0.548   0.961   0.963   0.974
471   P         0.931   0.934   0.944   1.039   1.042   1.055   0.961   0.963   0.974
472   Y         0.931   0.934   0.944   1.105   1.108   1.119   0.961   0.963   0.974
473   S         0.931   0.934   0.944   0.891   0.896   0.911   0.961   0.963   0.974
474   K         0.931   0.934   0.944   0.927   0.934   0.946   0.961   0.963   0.974
475   A         0.931   0.934   0.944   1.167   1.170   1.179   0.961   0.963   0.974
476   C        -0.571  -0.627  -0.640  -0.310  -0.409  -0.448  -0.680  -0.761  -0.777
477   D         0.931   0.934   0.944   0.952   0.957   0.970   0.961   0.963   0.974
478   A        -1.662  -1.647  -1.605  -1.403  -1.404  -1.313  -1.500  -1.477  -1.411
479   Y         0.931   0.934   0.944   1.105   1.108   1.119   0.961   0.963   0.974
480   P         0.931   0.934   0.944   1.039   1.042   1.055   0.961   0.963   0.974
481   S         0.931   0.934   0.944   0.891   0.896   0.911   0.961   0.963   0.974
482   V         0.931   0.934   0.944   1.060   1.062   1.076   0.961   0.963   0.974
483   R         0.931   0.934   0.944   1.029   1.029   1.045   0.961   0.963   0.974
484   T         0.931   0.934   0.944   1.085   1.087   1.099   0.961   0.963   0.974
485   Q         0.931   0.934   0.944   1.112   1.118   1.126   0.961   0.963   0.974
486   P         0.931   0.934   0.944   1.039   1.042   1.055   0.961   0.963   0.974
487   M         0.931   0.934   0.944   1.187   1.191   1.199   0.961   0.963   0.974
488   N         0.931   0.934   0.944   0.902   0.905   0.922   0.961   0.963   0.974
489   L         0.931   0.934   0.944   0.516   0.522   0.548   0.961   0.963   0.974
490   T        -0.571  -0.627  -0.640  -0.489  -0.594  -0.631  -0.680  -0.761  -0.777
491   N        -1.662  -1.647  -1.605  -1.637  -1.609  -1.539  -1.500  -1.477  -1.411
492   F         0.931   0.934   0.944   1.029   1.035   1.045   0.961   0.963   0.974
493   V         0.931   0.934   0.944   1.060   1.062   1.076   0.961   0.963   0.974
494   T        -0.571  -0.538  -0.628  -0.489  -0.432  -0.605  -0.680  -0.628  -0.758
495   K         0.931   0.934   0.944   0.927   0.934   0.946   0.961   0.963   0.974
496   M        -0.571  -0.521  -0.625  -0.568  -0.495  -0.624  -0.680  -0.601  -0.754
497   N         0.931   0.934   0.944   0.902   0.905   0.922   0.961   0.963   0.974
498   R        -1.662  -1.647  -1.605  -1.428  -1.412  -1.337  -1.500  -1.477  -1.411
499   N        -0.571  -0.627  -0.640  -0.558  -0.641  -0.649  -0.680  -0.761  -0.777
500   L        -1.662  -1.647  -1.605  -2.013  -1.961  -1.904  -1.500  -1.477  -1.411
501   L        -0.571  -0.627  -0.640  -0.950  -1.023  -1.004  -0.680  -0.761  -0.777
502   E        -1.662  -1.647  -1.605  -1.735  -1.679  -1.635  -1.500  -1.477  -1.411
503   Y         0.931   0.934   0.944   1.105   1.108   1.119   0.961   0.963   0.974
504   R        -0.571  -0.627  -0.640  -0.525  -0.626  -0.655  -0.680  -0.761  -0.777
505   N        -1.662  -1.647  -1.605  -1.602  -1.581  -1.505  -1.500  -1.477  -1.411
506   S        -0.571  -0.627  -0.640  -0.529  -0.603  -0.608  -0.680  -0.761  -0.777
507   K        -0.705  -0.700  -0.665  -0.764  -0.755  -0.693  -0.885  -0.874  -0.815
508   S         0.931   0.934   0.944   0.867   0.871   0.888   0.961   0.963   0.974
509   Q         0.931   0.934   0.944   1.101   1.105   1.115   0.961   0.963   0.974
510   L         0.931   0.934   0.944   0.556   0.561   0.586   0.961   0.963   0.974
511   V         0.931   0.934   0.944   1.087   1.091   1.101   0.961   0.963   0.974
512   P        -0.705  -0.700  -0.665  -0.785  -0.776  -0.713  -0.885  -0.874  -0.815
513   K         0.931   0.934   0.944   0.906   0.910   0.926   0.961   0.963   0.974
514   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
515   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
516   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
517   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
518   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
519   H         0.931   0.934   0.944   1.168   1.172   1.180   0.961   0.963   0.974
520   Q        -0.705  -0.700  -0.665  -0.629  -0.620  -0.562  -0.885  -0.874  -0.815
521   H        -0.705  -0.700  -0.665  -0.746  -0.737  -0.675  -0.885  -0.874  -0.815
522   S         0.931   0.934   0.944   0.887   0.892   0.908   0.961   0.963   0.974
523   T         0.931   0.934   0.944   1.051   1.056   1.067   0.961   0.963   0.974
524   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
525   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
526   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
527   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
528   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
529   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
530   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
531   H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
532   M        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
533   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
534   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
535   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
536   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
537   M        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
538   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
539   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
540   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
541   D        -0.705  -0.700  -0.665  -0.894  -0.885  -0.820  -0.885  -0.874  -0.815
542   D        -0.705  -0.700  -0.665  -0.795  -0.786  -0.723  -0.885  -0.874  -0.815
543   D        -0.705  -0.700  -0.665  -0.705  -0.696  -0.636  -0.885  -0.874  -0.815
544   D         0.931   0.934   0.944   0.935   0.939   0.954   0.961   0.963   0.974
545   D         0.931   0.934   0.944   0.935   0.939   0.954   0.961   0.963   0.974
546   D        -0.705  -0.700  -0.665  -0.795  -0.786  -0.723  -0.885  -0.874  -0.815
547   D         0.931   0.934   0.944   0.935   0.939   0.954   0.961   0.963   0.974
548   E        -0.705  -0.700  -0.665  -0.795  -0.786  -0.723  -0.885  -0.874  -0.815
549   I        -0.705  -0.700  -0.665  -0.862  -0.853  -0.788  -0.885  -0.874  -0.815
550   N         0.931   0.934   0.944   0.886   0.891   0.907   0.961   0.963   0.974
551   A        -0.705  -0.700  -0.665  -0.750  -0.741  -0.680  -0.885  -0.874  -0.815
552   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
553   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
554   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
555   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
556   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
557   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
558   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
559   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
560   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
561   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
562   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
563   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
564   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
565   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
566   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
567   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
568   L        -0.705  -0.700  -0.665  -1.060  -1.050  -0.980  -0.885  -0.874  -0.815
569   E        -0.705  -0.700  -0.665  -0.628  -0.619  -0.561  -0.885  -0.874  -0.815
570   L         0.931   0.934   0.944   0.556   0.561   0.586   0.961   0.963   0.974
571   P         0.931   0.934   0.944   1.039   1.042   1.055   0.961   0.963   0.974
572   H        -0.571  -0.627  -0.640  -0.439  -0.547  -0.595  -0.680  -0.761  -0.777
573   E        -0.571  -0.538  -0.628  -0.507  -0.455  -0.599  -0.680  -0.628  -0.758
574   S        -0.571  -0.521  -0.625  -0.531  -0.443  -0.637  -0.680  -0.601  -0.754
575   L        -0.571  -0.627  -0.640  -1.042  -1.126  -1.124  -0.680  -0.761  -0.777
576   T         0.931   0.934   0.944   1.085   1.087   1.099   0.961   0.963   0.974
577   K        -0.571  -0.627  -0.640  -0.586  -0.673  -0.695  -0.680  -0.761  -0.777
578   R        -1.662  -1.647  -1.605  -1.624  -1.607  -1.526  -1.500  -1.477  -1.411
579   D         0.931   0.934   0.944   0.952   0.957   0.970   0.961   0.963   0.974
580   I        -0.571  -0.627  -0.640  -0.629  -0.711  -0.719  -0.680  -0.761  -0.777
581   I        -0.571  -0.538  -0.628  -0.629  -0.577  -0.702  -0.680  -0.628  -0.758
582   M        -0.571  -0.521  -0.625  -0.497  -0.421  -0.561  -0.680  -0.601  -0.754
583   C         0.931   0.934   0.944   1.215   1.217   1.225   0.961   0.963   0.974
584   Y         0.931   0.934   0.944   1.105   1.108   1.119   0.961   0.963   0.974
585   H         0.931   0.934   0.944   1.160   1.164   1.172   0.961   0.963   0.974
586   A         0.931   0.934   0.944   1.167   1.170   1.179   0.961   0.963   0.974
587   L        -0.571  -0.627  -0.640  -0.868  -0.927  -0.899  -0.680  -0.761  -0.777
588   I        -0.571  -0.627  -0.640  -0.629  -0.711  -0.719  -0.680  -0.761  -0.777
589   H         0.931   0.934   0.944   1.160   1.164   1.172   0.961   0.963   0.974
590   H         0.931   0.934   0.944   1.160   1.164   1.172   0.961   0.963   0.974
591   F        -0.571  -0.627  -0.640  -0.536  -0.635  -0.670  -0.680  -0.761  -0.777
592   K         0.931   0.934   0.944   0.927   0.934   0.946   0.961   0.963   0.974
593   S        -0.571  -0.627  -0.640  -0.652  -0.743  -0.766  -0.680  -0.761  -0.777
594   I        -0.571  -0.521  -0.625  -0.508  -0.418  -0.623  -0.680  -0.601  -0.754
595   Y         0.931   0.934   0.944   1.105   1.108   1.119   0.961   0.963   0.974
596   V        -1.662  -1.647  -1.605  -1.440  -1.414  -1.349  -1.500  -1.477  -1.411
597   T         0.931   0.934   0.944   1.085   1.087   1.099   0.961   0.963   0.974
598   F        -0.571  -0.627  -0.640  -0.560  -0.662  -0.701  -0.680  -0.761  -0.777
599   L         0.931   0.934   0.944   0.516   0.522   0.548   0.961   0.963   0.974
600   K        -1.662  -1.647  -1.605  -1.639  -1.619  -1.541  -1.500  -1.477  -1.411
601   S        -1.662  -1.647  -1.605  -1.518  -1.502  -1.424  -1.500  -1.477  -1.411
602   F        -0.571  -0.627  -0.640  -0.707  -0.833  -0.895  -0.680  -0.761  -0.777
603   P        -0.571  -0.627  -0.640  -0.515  -0.613  -0.646  -0.680  -0.761  -0.777
604   H        -1.662  -1.647  -1.605  -1.474  -1.453  -1.381  -1.500  -1.477  -1.411
605   L         0.931   0.934   0.944   0.516   0.522   0.548   0.961   0.963   0.974
606   R         0.931   0.934   0.944   1.029   1.029   1.045   0.961   0.963   0.974
607   F        -0.571  -0.627  -0.640  -0.443  -0.529  -0.549  -0.680  -0.761  -0.777
608   L         0.931   0.934   0.944   0.516   0.522   0.548   0.961   0.963   0.974
609   M        -0.571  -0.627  -0.640  -0.321  -0.418  -0.451  -0.680  -0.761  -0.777
610   L         0.931   0.934   0.944   0.516   0.522   0.548   0.961   0.963   0.974
611   N         0.931   0.934   0.944   0.902   0.905   0.922   0.961   0.963   0.974
612   D         0.931   0.934   0.944   0.952   0.957   0.970   0.961   0.963   0.974
613   I        -0.571  -0.627  -0.640  -0.629  -0.711  -0.719  -0.680  -0.761  -0.777
614   P         0.931   0.934   0.944   1.039   1.042   1.055   0.961   0.963   0.974
615   T        -0.571  -0.627  -0.640  -0.344  -0.427  -0.442  -0.680  -0.761  -0.777
616   I         0.931   0.934   0.944   0.848   0.854   0.869   0.961   0.963   0.974
617   V        -0.571  -0.538  -0.628  -0.425  -0.375  -0.517  -0.680  -0.628  -0.758
618   M        -1.662  -1.647  -1.605  -1.677  -1.700  -1.578  -1.500  -1.477  -1.411
619   E         0.931   0.934   0.944   0.997   1.002   1.015   0.961   0.963   0.974
620   E        -0.571  -0.627  -0.640  -0.507  -0.599  -0.620  -0.680  -0.761  -0.777
621   N        -1.662  -1.647  -1.605  -1.637  -1.604  -1.539  -1.500  -1.477  -1.411
622   N        -0.571  -0.521  -0.625  -0.338  -0.247  -0.461  -0.680  -0.601  -0.754
623   E        -0.571  -0.627  -0.640  -0.443  -0.524  -0.537  -0.680  -0.761  -0.777
624   R         0.931   0.934   0.944   1.029   1.029   1.045   0.961   0.963   0.974
625   I        -0.571  -0.627  -0.640  -0.629  -0.711  -0.719  -0.680  -0.761  -0.777
626   F        -0.571  -0.627  -0.640  -0.473  -0.563  -0.588  -0.680  -0.761  -0.777
627   E        -1.662  -1.647  -1.605  -1.443  -1.416  -1.351  -1.500  -1.477  -1.411
628   P         0.931   0.934   0.944   1.039   1.042   1.055   0.961   0.963   0.974
629   V        -0.571  -0.538  -0.628  -0.531  -0.473  -0.649  -0.680  -0.628  -0.758
630   F         0.931   0.934   0.944   1.029   1.035   1.045   0.961   0.963   0.974
631   Y        -0.571  -0.627  -0.640  -0.409  -0.503  -0.534  -0.680  -0.761  -0.777
632   H        -0.571  -0.627  -0.640  -0.415  -0.521  -0.564  -0.680  -0.761  -0.777
633   Y        -1.662  -1.647  -1.605  -1.606  -1.590  -1.510  -1.500  -1.477  -1.411
634   D        -0.571  -0.521  -0.625  -0.316  -0.227  -0.435  -0.680  -0.601  -0.754
635   Y         0.931   0.934   0.944   1.105   1.108   1.119   0.961   0.963   0.974
636   K        -0.571  -0.538  -0.628  -0.533  -0.478  -0.608  -0.680  -0.628  -0.758
637   S        -0.571  -0.538  -0.628  -0.578  -0.527  -0.653  -0.680  -0.628  -0.758
638   N         0.931   0.934   0.944   0.902   0.905   0.922   0.961   0.963   0.974
639   L        -0.571  -0.627  -0.640  -0.868  -0.927  -0.899  -0.680  -0.761  -0.777
640   Y        -1.662  -1.647  -1.605  -1.287  -1.254  -1.200  -1.500  -1.477  -1.411
641   G        -0.571  -0.627  -0.640  -0.338  -0.447  -0.496  -0.680  -0.761  -0.777
642   W         0.931   0.934   0.944   1.271   1.275   1.280   0.961   0.963   0.974
643   S         0.931   0.934   0.944   0.867   0.871   0.888   0.961   0.963   0.974
644   K         0.931   0.934   0.944   0.906   0.910   0.926   0.961   0.963   0.974
645   E        -0.705  -0.700  -0.665  -0.675  -0.666  -0.607  -0.885  -0.874  -0.815
646   S        -0.705  -0.700  -0.665  -0.834  -0.825  -0.761  -0.885  -0.874  -0.815
647   N        -0.705  -0.700  -0.665  -0.902  -0.892  -0.827  -0.885  -0.874  -0.815
648   K         0.931   0.934   0.944   0.906   0.910   0.926   0.961   0.963   0.974
649   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
650   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
651   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
652   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
653   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
654   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
655   N         0.931   0.934   0.944   0.886   0.891   0.907   0.961   0.963   0.974
656   N        -0.705  -0.700  -0.665  -0.774  -0.765  -0.703  -0.885  -0.874  -0.815
657   N         0.931   0.934   0.944   0.886   0.891   0.907   0.961   0.963   0.974
658   N        -0.705  -0.700  -0.665  -0.736  -0.727  -0.666  -0.885  -0.874  -0.815
659   N        -0.705  -0.700  -0.665  -0.931  -0.921  -0.855  -0.885  -0.874  -0.815
660   N        -0.705  -0.700  -0.665  -0.830  -0.821  -0.758  -0.885  -0.874  -0.815
661   S        -0.705  -0.700  -0.665  -0.813  -0.804  -0.740  -0.885  -0.874  -0.815
662   D        -0.705  -0.700  -0.665  -0.880  -0.871  -0.806  -0.885  -0.874  -0.815
663   T        -0.705  -0.700  -0.665  -0.740  -0.731  -0.670  -0.885  -0.874  -0.815
664   I        -0.705  -0.700  -0.665  -0.809  -0.800  -0.737  -0.885  -0.874  -0.815
665   A         0.931   0.934   0.944   1.129   1.133   1.142   0.961   0.963   0.974
666   R        -0.705  -0.700  -0.665  -0.764  -0.755  -0.693  -0.885  -0.874  -0.815
667   I        -0.705  -0.700  -0.665  -0.945  -0.935  -0.869  -0.885  -0.874  -0.815
668   A         0.931   0.934   0.944   1.129   1.133   1.142   0.961   0.963   0.974
669   T         0.931   0.934   0.944   1.077   1.081   1.092   0.961   0.963   0.974
670   V         0.931   0.934   0.944   1.087   1.091   1.101   0.961   0.963   0.974
671   M        -1.662  -1.647  -1.605  -1.391  -1.355  -1.301  -1.500  -1.477  -1.411
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P47005
Output conservation file - output/P47005
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
