1     M         2.075   2.094   2.156   2.331   2.358   2.456   2.326   2.360   2.467
2     V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     S        -0.822  -0.796  -0.735  -0.950  -0.883  -0.821  -0.826  -0.797  -0.719
4     K        -0.822  -0.796  -0.735  -0.793  -0.747  -0.664  -0.826  -0.797  -0.719
5     T        -0.098  -0.075  -0.071  -0.191  -0.144  -0.146  -0.300  -0.274  -0.273
6     W        -0.709  -0.696  -0.662  -0.716  -0.704  -0.642  -0.700  -0.684  -0.638
7     I        -1.187  -1.214  -1.145  -1.042  -1.089  -0.985  -0.942  -0.967  -0.881
8     C        -1.187  -1.146  -1.145  -1.094  -1.054  -1.019  -0.942  -0.900  -0.881
9     G        -0.522  -0.457  -0.559  -0.446  -0.352  -0.532  -0.476  -0.397  -0.516
10    F        -0.704  -0.714  -0.653  -0.709  -0.726  -0.625  -0.709  -0.717  -0.637
11    I        -0.039  -0.049  -0.046  -0.204  -0.219  -0.211  -0.242  -0.261  -0.251
12    S        -0.704  -0.680  -0.674  -0.868  -0.841  -0.807  -0.709  -0.682  -0.657
13    I        -1.187  -1.189  -1.135  -0.917  -0.900  -0.826  -0.942  -0.944  -0.872
14    I        -0.704  -0.739  -0.658  -0.610  -0.637  -0.531  -0.709  -0.740  -0.641
15    T        -1.187  -1.199  -1.137  -1.076  -1.105  -1.009  -0.942  -0.953  -0.874
16    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    V        -1.187  -1.126  -1.137  -1.102  -1.011  -1.042  -0.942  -0.881  -0.874
18    V        -0.039  -0.027  -0.022  -0.167  -0.159  -0.148  -0.242  -0.225  -0.218
19    Q        -1.187  -1.189  -1.135  -1.139  -1.151  -1.057  -0.942  -0.944  -0.872
20    A         1.134   1.237   1.027   1.228   1.362   1.073   1.159   1.328   0.955
21    L        -1.187  -1.168  -1.161  -1.094  -1.070  -1.047  -0.942  -0.925  -0.896
22    S        -0.704  -0.701  -0.669  -0.838  -0.837  -0.777  -0.709  -0.700  -0.649
23    C         2.075   2.094   2.156   2.276   2.307   2.402   2.326   2.360   2.467
24    E        -1.187  -1.172  -1.136  -1.180  -1.139  -1.101  -0.942  -0.929  -0.873
25    K        -1.187  -1.175  -1.161  -1.160  -1.125  -1.116  -0.942  -0.932  -0.896
26    H        -0.704  -0.739  -0.695  -0.591  -0.624  -0.559  -0.709  -0.740  -0.678
27    D        -0.522  -0.571  -0.614  -0.389  -0.477  -0.555  -0.476  -0.539  -0.582
28    V        -0.098  -0.125  -0.085  -0.205  -0.269  -0.198  -0.300  -0.345  -0.294
29    L         1.134   1.026   0.974   1.075   0.920   0.827   1.159   0.972   0.857
30    K        -0.522  -0.503  -0.561  -0.558  -0.530  -0.628  -0.476  -0.452  -0.519
31    K        -0.704  -0.622  -0.662  -0.704  -0.592  -0.614  -0.709  -0.624  -0.644
32    Y         2.075   2.094   2.156   2.238   2.262   2.364   2.326   2.360   2.467
33    Q        -0.704  -0.670  -0.658  -0.589  -0.549  -0.499  -0.709  -0.672  -0.641
34    V        -0.039  -0.070  -0.042  -0.120  -0.166  -0.128  -0.242  -0.270  -0.235
35    G        -1.187  -1.212  -1.184  -1.114  -1.183  -1.140  -0.942  -0.965  -0.917
36    K        -1.187  -1.212  -1.184  -1.211  -1.239  -1.193  -0.942  -0.965  -0.917
37    F        -0.039  -0.033  -0.054  -0.090  -0.072  -0.122  -0.242  -0.229  -0.258
38    S        -0.039  -0.005  -0.009  -0.344  -0.275  -0.281  -0.242  -0.184  -0.188
39    S        -0.039   0.003  -0.054  -0.233  -0.179  -0.264  -0.242  -0.194  -0.260
40    L        -1.187  -1.168  -1.161  -1.120  -1.088  -1.077  -0.942  -0.925  -0.896
41    T        -1.187  -1.212  -1.184  -0.951  -1.030  -1.025  -0.942  -0.965  -0.917
42    S         0.262   0.243   0.105   0.181   0.148  -0.069   0.225   0.196  -0.014
43    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
44    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
45    T        -0.522  -0.613  -0.623  -0.386  -0.520  -0.553  -0.476  -0.587  -0.593
46    E        -0.704  -0.739  -0.695  -0.763  -0.804  -0.738  -0.709  -0.740  -0.678
47    R        -1.187  -1.212  -1.184  -1.026  -1.056  -0.984  -0.942  -0.965  -0.917
48    D         0.262   0.211   0.117   0.340   0.265   0.126   0.225   0.144   0.004
49    T         2.075   2.094   2.156   2.063   2.096   2.189   2.326   2.360   2.467
50    P         2.075   2.094   2.156   2.221   2.238   2.347   2.326   2.360   2.467
51    P         2.075   2.094   2.156   2.221   2.238   2.347   2.326   2.360   2.467
52    S         1.134   1.237   1.027   1.049   1.183   0.906   1.159   1.328   0.955
53    T        -0.704  -0.659  -0.667  -0.641  -0.594  -0.610  -0.709  -0.657  -0.647
54    T         1.134   1.026   0.974   1.251   1.118   1.050   1.159   0.972   0.857
55    I        -0.704  -0.668  -0.671  -0.847  -0.802  -0.808  -0.709  -0.667  -0.651
56    E        -0.039  -0.070  -0.042  -0.031  -0.044   0.006  -0.242  -0.270  -0.235
57    K        -1.187  -1.212  -1.184  -1.049  -1.078  -1.051  -0.942  -0.965  -0.917
58    W         1.134   1.026   0.974   1.436   1.293   1.211   1.159   0.972   0.857
59    W        -0.704  -0.717  -0.665  -0.452  -0.487  -0.402  -0.709  -0.720  -0.647
60    I        -0.039   0.053  -0.014  -0.204  -0.057  -0.162  -0.242  -0.109  -0.204
61    N        -0.704  -0.746  -0.696  -0.770  -0.834  -0.743  -0.709  -0.747  -0.678
62    V        -0.039  -0.019  -0.049  -0.026  -0.009  -0.034  -0.242  -0.232  -0.256
63    C         2.075   2.094   2.156   2.276   2.307   2.402   2.326   2.360   2.467
64    E        -0.704  -0.717  -0.668  -0.631  -0.651  -0.562  -0.709  -0.720  -0.650
65    E        -1.187  -1.175  -1.161  -1.049  -1.066  -1.023  -0.942  -0.932  -0.896
66    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
67    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
68    H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
69    N        -0.704  -0.668  -0.671  -0.762  -0.713  -0.715  -0.709  -0.667  -0.651
70    V         0.262   0.217   0.104   0.181   0.099  -0.072   0.225   0.152  -0.017
71    E        -0.704  -0.670  -0.658  -0.682  -0.638  -0.600  -0.709  -0.669  -0.641
72    P        -0.709  -0.625  -0.673  -0.710  -0.596  -0.648  -0.700  -0.600  -0.650
73    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
74    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
75    P        -0.039  -0.070  -0.042   0.011  -0.034   0.007  -0.242  -0.270  -0.235
76    E        -0.704  -0.678  -0.652  -0.818  -0.773  -0.747  -0.709  -0.679  -0.635
77    E        -0.704  -0.624  -0.665  -0.463  -0.353  -0.387  -0.709  -0.627  -0.647
78    C         2.075   2.094   2.156   2.276   2.307   2.402   2.326   2.360   2.467
79    K        -0.522  -0.498  -0.617  -0.333  -0.311  -0.537  -0.476  -0.447  -0.585
80    K        -1.187  -1.214  -1.145  -1.253  -1.305  -1.195  -0.942  -0.967  -0.881
81    N         0.262   0.243   0.105   0.339   0.310   0.080   0.225   0.196  -0.014
82    D        -0.039  -0.070  -0.042  -0.248  -0.272  -0.237  -0.242  -0.270  -0.235
83    M        -0.704  -0.668  -0.671  -0.670  -0.617  -0.593  -0.709  -0.667  -0.651
84    L        -1.187  -1.214  -1.145  -0.999  -1.031  -0.924  -0.942  -0.967  -0.881
85    C         2.075   2.094   2.156   2.276   2.307   2.402   2.326   2.360   2.467
86    G         1.134   1.122   0.990   1.122   1.103   0.925   1.159   1.137   0.886
87    L        -0.221  -0.203  -0.135  -0.472  -0.448  -0.343  -0.476  -0.452  -0.364
88    T         0.262   0.148   0.074   0.411   0.242   0.137   0.225   0.056  -0.060
89    D        -1.187  -1.172  -1.136  -1.052  -1.006  -0.964  -0.942  -0.929  -0.873
90    V         0.627   0.643   0.711   0.362   0.385   0.489   0.225   0.248   0.344
91    I        -1.187  -1.126  -1.137  -1.171  -1.081  -1.099  -0.942  -0.881  -0.874
92    L         0.262   0.293   0.135   0.328   0.369   0.157   0.225   0.268   0.030
93    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
94    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
95    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
96    P        -0.522  -0.434  -0.570  -0.350  -0.216  -0.465  -0.476  -0.368  -0.529
97    G        -0.522  -0.499  -0.610  -0.538  -0.526  -0.697  -0.476  -0.454  -0.577
98    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
99    K         0.262   0.293   0.135   0.218   0.266   0.019   0.225   0.268   0.030
100   D         0.262   0.308   0.144   0.306   0.379   0.121   0.225   0.291   0.043
101   A        -1.187  -1.214  -1.145  -0.874  -0.919  -0.807  -0.942  -0.967  -0.881
102   I        -0.039  -0.033  -0.054  -0.167  -0.156  -0.196  -0.242  -0.229  -0.258
103   T         0.089   0.019  -0.004   0.077  -0.047  -0.093  -0.027  -0.134  -0.175
104   T         0.627   0.643   0.711   0.264   0.286   0.393   0.225   0.248   0.344
105   Q        -0.039  -0.026  -0.054  -0.010   0.014  -0.038  -0.242  -0.222  -0.258
106   I        -0.039  -0.003  -0.016  -0.176  -0.111  -0.145  -0.242  -0.180  -0.207
107   I        -0.704  -0.668  -0.671  -0.572  -0.497  -0.503  -0.709  -0.667  -0.651
108   D        -0.522  -0.499  -0.610  -0.468  -0.430  -0.621  -0.476  -0.454  -0.577
109   F         1.134   1.122   0.990   1.291   1.283   1.080   1.159   1.137   0.886
110   D        -1.670  -1.640  -1.580  -1.465  -1.418  -1.335  -1.176  -1.149  -1.073
111   K        -0.704  -0.700  -0.668  -0.911  -0.902  -0.845  -0.709  -0.704  -0.651
112   N        -0.704  -0.713  -0.668  -0.864  -0.897  -0.809  -0.709  -0.714  -0.651
113   I        -1.187  -1.212  -1.184  -1.066  -1.094  -1.041  -0.942  -0.965  -0.917
114   G        -0.704  -0.668  -0.671  -0.612  -0.572  -0.595  -0.709  -0.667  -0.651
115   F        -1.187  -1.212  -1.184  -1.029  -1.046  -0.987  -0.942  -0.965  -0.917
116   N        -0.704  -0.644  -0.668  -0.528  -0.444  -0.473  -0.709  -0.647  -0.651
117   V         0.627   0.643   0.711   0.483   0.500   0.609   0.225   0.248   0.344
118   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
119   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
120   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
121   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
122   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
123   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
124   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
125   E        -0.522  -0.539  -0.573  -0.370  -0.395  -0.462  -0.476  -0.502  -0.533
126   E         0.262   0.394   0.132   0.374   0.565   0.162   0.225   0.416   0.026
127   T        -1.187  -1.175  -1.161  -1.173  -1.173  -1.157  -0.942  -0.932  -0.896
128   E        -0.522  -0.565  -0.581  -0.367  -0.439  -0.472  -0.476  -0.531  -0.543
129   S        -0.704  -0.624  -0.665  -0.808  -0.689  -0.735  -0.709  -0.627  -0.647
130   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
131   A         0.745   0.779   0.787   0.536   0.583   0.592   0.458   0.517   0.498
132   L        -0.039  -0.005  -0.009  -0.167  -0.099  -0.100  -0.242  -0.184  -0.188
133   T        -0.704  -0.670  -0.658  -0.881  -0.838  -0.817  -0.709  -0.669  -0.641
134   L        -0.522  -0.521  -0.557  -0.426  -0.427  -0.498  -0.476  -0.480  -0.514
135   T        -1.187  -1.139  -1.149  -0.953  -0.897  -0.926  -0.942  -0.897  -0.885
136   L        -0.039  -0.033  -0.054   0.004   0.021  -0.022  -0.242  -0.229  -0.258
137   K         0.089   0.037  -0.013  -0.101  -0.192  -0.305  -0.027  -0.105  -0.189
138   G         2.075   2.094   2.156   1.970   1.994   2.096   2.326   2.360   2.467
139   A         0.262   0.148   0.074   0.410   0.231   0.114   0.225   0.056  -0.060
140   T        -1.187  -1.212  -1.184  -1.026  -1.063  -1.025  -0.942  -0.965  -0.917
141   W         2.075   2.094   2.156   2.276   2.307   2.402   2.326   2.360   2.467
142   G         2.075   2.094   2.156   1.970   1.994   2.096   2.326   2.360   2.467
143   A        -0.039   0.056   0.007  -0.268  -0.128  -0.176  -0.242  -0.107  -0.165
144   N        -0.522  -0.565  -0.581  -0.301  -0.368  -0.381  -0.476  -0.531  -0.543
145   S        -1.187  -1.212  -1.184  -1.258  -1.298  -1.269  -0.942  -0.965  -0.917
146   F        -0.704  -0.668  -0.671  -0.762  -0.712  -0.697  -0.709  -0.667  -0.651
147   D         0.745   0.777   0.769   0.559   0.611   0.579   0.458   0.511   0.461
148   A         1.134   1.026   0.974   1.248   1.094   1.019   1.159   0.972   0.857
149   K        -0.704  -0.668  -0.671  -0.762  -0.704  -0.721  -0.709  -0.667  -0.651
150   L         0.262   0.163   0.082   0.275   0.129   0.001   0.225   0.077  -0.049
151   E        -1.187  -1.126  -1.137  -0.945  -0.877  -0.869  -0.942  -0.881  -0.874
152   F        -0.039  -0.060  -0.053   0.033  -0.000   0.008  -0.242  -0.279  -0.261
153   Q        -0.522  -0.550  -0.577  -0.261  -0.319  -0.382  -0.476  -0.515  -0.538
154   C         2.075   2.094   2.156   2.276   2.307   2.402   2.326   2.360   2.467
155   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
156   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
157   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
158   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
159   N        -0.522  -0.560  -0.606  -0.423  -0.499  -0.556  -0.476  -0.526  -0.573
160   D        -0.704  -0.701  -0.669  -0.821  -0.797  -0.743  -0.709  -0.700  -0.649
161   N        -0.221  -0.195  -0.121  -0.506  -0.468  -0.361  -0.476  -0.442  -0.346
162   M        -1.289  -1.257  -1.200  -1.244  -1.185  -1.115  -1.036  -1.005  -0.931
163   K        -1.187  -1.168  -1.161  -1.125  -1.096  -1.075  -0.942  -0.925  -0.896
164   Q        -1.670  -1.640  -1.580  -1.548  -1.524  -1.418  -1.176  -1.149  -1.073
165   D        -0.522  -0.565  -0.581  -0.418  -0.484  -0.510  -0.476  -0.531  -0.543
166   E        -0.039  -0.044  -0.028  -0.207  -0.222  -0.207  -0.242  -0.252  -0.224
167   L         0.745   0.823   0.838   0.554   0.684   0.698   0.458   0.601   0.599
168   T        -0.522  -0.550  -0.577  -0.331  -0.388  -0.412  -0.476  -0.515  -0.538
169   S        -1.187  -1.212  -1.184  -1.189  -1.219  -1.187  -0.942  -0.965  -0.917
170   H        -1.187  -1.214  -1.145  -0.919  -0.996  -0.889  -0.942  -0.967  -0.881
171   T        -1.187  -1.212  -1.184  -0.987  -1.058  -1.041  -0.942  -0.965  -0.917
172   W         1.134   1.026   0.974   1.399   1.245   1.151   1.159   0.972   0.857
173   A        -1.187  -1.212  -1.184  -1.117  -1.174  -1.117  -0.942  -0.965  -0.917
174   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
175   D        -0.522  -0.576  -0.586  -0.519  -0.614  -0.645  -0.476  -0.544  -0.549
176   K        -1.187  -1.214  -1.145  -1.065  -1.090  -0.991  -0.942  -0.967  -0.881
177   S        -0.704  -0.619  -0.651  -0.559  -0.443  -0.475  -0.709  -0.621  -0.634
178   I        -0.704  -0.710  -0.686  -0.732  -0.722  -0.671  -0.709  -0.712  -0.668
179   Q        -0.522  -0.571  -0.614  -0.474  -0.548  -0.602  -0.476  -0.539  -0.582
180   L        -0.039   0.003  -0.031  -0.204  -0.155  -0.189  -0.242  -0.208  -0.231
181   T        -1.187  -1.212  -1.184  -1.186  -1.223  -1.164  -0.942  -0.965  -0.917
182   L        -1.187  -1.165  -1.132  -0.781  -0.734  -0.712  -0.942  -0.922  -0.869
183   K         0.745   0.744   0.765   0.405   0.402   0.406   0.458   0.449   0.453
184   G         0.627   0.643   0.711   0.312   0.334   0.439   0.225   0.248   0.344
185   P         0.745   0.823   0.838   0.689   0.824   0.836   0.458   0.601   0.599
186   S        -0.039  -0.026  -0.054  -0.144  -0.126  -0.164  -0.242  -0.222  -0.258
187   G         0.627   0.643   0.711   0.341   0.356   0.468   0.225   0.248   0.344
188   C         2.075   2.094   2.156   2.276   2.307   2.402   2.326   2.360   2.467
189   L        -0.039  -0.033  -0.054  -0.200  -0.179  -0.240  -0.242  -0.229  -0.258
190   K        -0.704  -0.746  -0.696  -0.717  -0.762  -0.676  -0.709  -0.747  -0.678
191   S        -0.039  -0.003  -0.013  -0.287  -0.214  -0.257  -0.242  -0.185  -0.205
192   K         0.627   0.655   0.719   0.212   0.264   0.361   0.225   0.271   0.361
193   D        -1.187  -1.139  -1.149  -1.180  -1.118  -1.144  -0.942  -0.897  -0.885
194   D         0.262   0.148   0.074   0.259   0.078  -0.066   0.225   0.056  -0.060
195   D        -0.704  -0.739  -0.695  -0.773  -0.800  -0.725  -0.709  -0.740  -0.678
196   K         2.075   2.094   2.156   1.918   1.956   2.044   2.326   2.360   2.467
197   K         0.089   0.004  -0.013   0.029  -0.082  -0.121  -0.027  -0.154  -0.189
198   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
199   N        -0.709  -0.742  -0.691  -0.795  -0.864  -0.796  -0.700  -0.737  -0.670
200   G         0.089   0.018  -0.000  -0.020  -0.145  -0.180  -0.027  -0.134  -0.170
201   D         0.089   0.018  -0.000   0.035  -0.081  -0.125  -0.027  -0.134  -0.170
202   G        -1.289  -1.264  -1.200  -1.290  -1.246  -1.160  -1.036  -1.011  -0.931
203   D         0.669   0.664   0.720   0.343   0.317   0.402   0.309   0.289   0.363
204   N         2.075   2.094   2.156   2.055   2.078   2.181   2.326   2.360   2.467
205   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
206   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
207   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
208   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
209   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
210   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
211   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
212   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
213   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
214   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
215   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
216   G         0.669   0.705   0.742   0.527   0.585   0.629   0.309   0.371   0.407
217   K        -0.709  -0.625  -0.673  -0.642  -0.513  -0.591  -0.700  -0.600  -0.650
218   D         0.262   0.293   0.135   0.340   0.385   0.153   0.225   0.268   0.030
219   G        -0.039  -0.005  -0.009  -0.270  -0.200  -0.201  -0.242  -0.184  -0.188
220   D         0.262   0.293   0.135   0.404   0.444   0.241   0.225   0.268   0.030
221   S        -0.522  -0.498  -0.617  -0.531  -0.492  -0.717  -0.476  -0.447  -0.585
222   E        -0.522  -0.571  -0.614  -0.368  -0.452  -0.516  -0.476  -0.539  -0.582
223   G         1.134   1.026   0.974   1.083   0.919   0.834   1.159   0.972   0.857
224   K        -0.704  -0.739  -0.695  -0.829  -0.879  -0.828  -0.709  -0.740  -0.678
225   K        -0.704  -0.746  -0.696  -0.967  -1.027  -0.947  -0.709  -0.747  -0.678
226   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
227   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
228   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
229   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
230   A        -0.098  -0.131  -0.085  -0.233  -0.303  -0.246  -0.300  -0.353  -0.294
231   G        -0.098  -0.131  -0.085  -0.276  -0.332  -0.262  -0.300  -0.353  -0.294
232   G        -0.822  -0.792  -0.735  -1.169  -1.127  -1.039  -0.826  -0.792  -0.719
233   T        -0.039  -0.026  -0.054   0.040   0.063  -0.004  -0.242  -0.222  -0.258
234   S         0.627   0.643   0.711   0.193   0.210   0.321   0.225   0.248   0.344
235   W         2.075   2.094   2.156   2.276   2.307   2.402   2.326   2.360   2.467
236   F         1.134   1.139   0.998   1.279   1.296   1.075   1.159   1.167   0.902
237   T         1.134   1.139   0.998   1.200   1.213   1.006   1.159   1.167   0.902
238   W         2.075   2.094   2.156   2.276   2.307   2.402   2.326   2.360   2.467
239   L         0.745   0.823   0.838   0.516   0.650   0.660   0.458   0.601   0.599
240   F         2.075   2.094   2.156   2.155   2.191   2.281   2.326   2.360   2.467
241   L        -0.522  -0.498  -0.617  -0.341  -0.302  -0.488  -0.476  -0.447  -0.585
242   Y        -0.039  -0.070  -0.042   0.085   0.049   0.086  -0.242  -0.270  -0.235
243   A        -0.039  -0.070  -0.042  -0.135  -0.164  -0.126  -0.242  -0.270  -0.235
244   L        -0.522  -0.498  -0.617  -0.455  -0.420  -0.620  -0.476  -0.447  -0.585
245   L         1.134   1.139   0.998   1.109   1.125   0.922   1.159   1.167   0.902
246   F         1.134   1.026   0.974   1.280   1.130   1.036   1.159   0.972   0.857
247   T        -0.704  -0.739  -0.695  -0.772  -0.818  -0.743  -0.709  -0.740  -0.678
248   L        -0.704  -0.746  -0.696  -0.887  -0.938  -0.851  -0.709  -0.747  -0.678
249   I         1.134   1.026   0.974   1.211   1.062   0.976   1.159   0.972   0.857
250   Y         2.075   2.094   2.156   2.238   2.262   2.364   2.326   2.360   2.467
251   L         0.627   0.643   0.711   0.314   0.344   0.442   0.225   0.248   0.344
252   M        -0.221  -0.202  -0.132  -0.243  -0.219  -0.123  -0.476  -0.451  -0.361
253   V         0.627   0.643   0.711   0.285   0.301   0.413   0.225   0.248   0.344
254   V        -0.704  -0.739  -0.695  -0.793  -0.842  -0.764  -0.709  -0.740  -0.678
255   S         0.627   0.643   0.711   0.293   0.310   0.420   0.225   0.248   0.344
256   F        -0.039   0.003  -0.054   0.182   0.234   0.161  -0.242  -0.194  -0.260
257   L        -0.704  -0.739  -0.695  -0.611  -0.654  -0.574  -0.709  -0.740  -0.678
258   N         0.745   0.823   0.838   0.701   0.821   0.843   0.458   0.601   0.599
259   T         0.627   0.643   0.711   0.508   0.530   0.635   0.225   0.248   0.344
260   R        -1.187  -1.175  -1.161  -1.013  -1.006  -1.021  -0.942  -0.932  -0.896
261   G        -0.704  -0.739  -0.695  -0.782  -0.802  -0.728  -0.709  -0.740  -0.678
262   G         2.075   2.094   2.156   1.992   2.022   2.118   2.326   2.360   2.467
263   S         0.669   0.703   0.758   0.308   0.353   0.444   0.309   0.367   0.438
264   F         0.669   0.703   0.758   0.556   0.614   0.693   0.309   0.367   0.438
265   Q        -0.130  -0.131  -0.101  -0.102  -0.095  -0.053  -0.363  -0.362  -0.320
266   D         2.075   2.094   2.156   2.010   2.042   2.135   2.326   2.360   2.467
267   F         1.134   1.026   0.974   1.333   1.198   1.123   1.159   0.972   0.857
268   R        -0.039  -0.070  -0.042   0.152   0.103   0.137  -0.242  -0.270  -0.235
269   A        -0.704  -0.659  -0.667  -0.786  -0.711  -0.695  -0.709  -0.657  -0.647
270   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
271   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
272   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
273   E         1.134   1.026   0.974   1.229   1.079   0.992   1.159   0.972   0.857
274   F        -0.039  -0.070  -0.042  -0.084  -0.118  -0.092  -0.242  -0.270  -0.235
275   I        -0.039   0.000  -0.018  -0.199  -0.155  -0.165  -0.242  -0.199  -0.210
276   Q        -0.522  -0.560  -0.606  -0.268  -0.330  -0.385  -0.476  -0.526  -0.573
277   R        -0.039  -0.070  -0.042   0.147   0.135   0.179  -0.242  -0.270  -0.235
278   S        -0.704  -0.746  -0.696  -0.767  -0.834  -0.763  -0.709  -0.747  -0.678
279   T        -0.522  -0.499  -0.610  -0.417  -0.392  -0.573  -0.476  -0.454  -0.577
280   Q        -0.704  -0.670  -0.658  -0.718  -0.683  -0.632  -0.709  -0.672  -0.641
281   F         0.669   0.703   0.758   0.455   0.519   0.594   0.309   0.367   0.438
282   L         0.262   0.243   0.105   0.294   0.270   0.065   0.225   0.196  -0.014
283   T        -0.039  -0.070  -0.042  -0.126  -0.130  -0.092  -0.242  -0.270  -0.235
284   S        -0.704  -0.739  -0.695  -0.900  -0.956  -0.876  -0.709  -0.740  -0.678
285   L         1.134   1.026   0.974   1.100   0.952   0.868   1.159   0.972   0.857
286   P         2.075   2.094   2.156   2.221   2.238   2.347   2.326   2.360   2.467
287   E        -1.187  -1.212  -1.184  -1.015  -1.029  -0.963  -0.942  -0.965  -0.917
288   F         1.134   1.026   0.974   1.279   1.131   1.034   1.159   0.972   0.857
289   C        -1.187  -1.182  -1.132  -1.015  -1.023  -0.931  -0.942  -0.938  -0.868
290   K         0.745   0.739   0.769   0.584   0.582   0.626   0.458   0.439   0.462
291   E         1.134   1.026   0.974   1.229   1.079   0.992   1.159   0.972   0.857
292   V        -0.039  -0.070  -0.042  -0.167  -0.210  -0.173  -0.242  -0.270  -0.235
293   V        -0.039  -0.026  -0.054  -0.114  -0.094  -0.134  -0.242  -0.222  -0.258
294   S        -1.187  -1.212  -1.184  -1.116  -1.161  -1.142  -0.942  -0.965  -0.917
295   R         1.134   1.205   1.009   1.120   1.219   0.973   1.159   1.275   0.922
296   I        -0.704  -0.746  -0.696  -0.644  -0.707  -0.638  -0.709  -0.747  -0.678
297   L        -0.221  -0.195  -0.121  -0.479  -0.440  -0.329  -0.476  -0.442  -0.346
298   G         1.134   1.139   0.998   1.115   1.120   0.927   1.159   1.167   0.902
299   R        -0.704  -0.646  -0.651  -0.605  -0.537  -0.534  -0.709  -0.646  -0.634
300   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
301   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
302   S         0.900   0.810   0.839   0.673   0.531   0.563   0.750   0.575   0.600
303   T        -0.098  -0.099  -0.071  -0.415  -0.429  -0.384  -0.300  -0.310  -0.273
304   A         0.745   0.771   0.779   0.476   0.509   0.520   0.458   0.501   0.481
305   Q        -0.221  -0.194  -0.119  -0.361  -0.339  -0.222  -0.476  -0.440  -0.343
306   R         2.075   2.094   2.156   2.280   2.309   2.405   2.326   2.360   2.467
307   G         1.134   1.026   0.974   1.114   0.962   0.887   1.159   0.972   0.857
308   G         0.745   0.823   0.838   0.533   0.656   0.677   0.458   0.601   0.599
309   Y         2.075   2.094   2.156   2.238   2.262   2.364   2.326   2.360   2.467
310   S         2.075   2.094   2.156   1.904   1.930   2.030   2.326   2.360   2.467
311   A         2.075   2.094   2.156   2.102   2.126   2.228   2.326   2.360   2.467
312   V         2.075   2.094   2.156   2.028   2.053   2.153   2.326   2.360   2.467
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P46989
Output conservation file - output/P46989
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
